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Long-term effect of stent placement in 115 patients with Budd-Chiari syndrome 被引量:38
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作者 Chun-QingZhang Li-NaFu +5 位作者 LinXu Guo-QuanZhang TaoJia Ji-YongLiu Cheng-YongQin Ju-RenZhu 《World Journal of Gastroenterology》 SCIE CAS CSCD 2003年第11期2587-2591,共5页
AIM: To report the long-term effect of stent placement in 115 patients with Budd-Chiari syndrome (BCS).METHODS: One hundred and fifteen patients with BCS were treated by percutaneous stent placement. One hundred and t... AIM: To report the long-term effect of stent placement in 115 patients with Budd-Chiari syndrome (BCS).METHODS: One hundred and fifteen patients with BCS were treated by percutaneous stent placement. One hundred and two patients had IVC stent placement, 30 patients had HV stent placement, 17 of them underwent both IVC stent and HV stent. All the procedures were performed with guidance of ultrasound.RESULTS: The successful rates in placing IVC stent and HV stent were 94 % (96/102) and 87 % (26/30), respectively.Ninety-seven patients with 112 stents (90 IVC stents, 22 HV stents) were followed up. 96.7 %(87/90) IVC stents and 90.9 %(20/22) HV stents remained patent during follow up periods (mean 49 months, 45 months, respectively). Five of 112 stents in the 97 patients developed occlusion. Absence of anticoagulants after the procedure and types of obstruction (segmental and occlusive) before the procedure were related to a higher incidence of stent occlusion.CONCLUSION: Patients with BCS caused by short length obstruction can be treated by IVC stent placement, HV stent placement or both IVC and HV stent placement depending on the sites of obstruction. The long-term effect is satisfactory.Anticoagulants are strongly recommended after the procedure especially for BCS patients caused by segmental occlusion. 展开更多
关键词 布加综合征 支架置入术 长期疗效 hv支架 抗凝血剂
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RGD肽联合转化生长因子-β_1对组织工程瓣膜构建的影响 被引量:11
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作者 史嘉玮 董念国 +1 位作者 孙宗全 仇玉明 《中华医学杂志》 CAS CSCD 北大核心 2006年第29期2074-2077,共4页
细胞对支架的黏附和生长是构建组织工程心脏瓣膜(tissue engineering heart valve,TEHV)的关键环节。去细胞瓣被认为是一种较理想的TEHV支架,本实验率先采用RGD肽(精-甘-天冬氨酸,Arg-Gly-Asp)表面修饰以促进细胞黏附,联合种植... 细胞对支架的黏附和生长是构建组织工程心脏瓣膜(tissue engineering heart valve,TEHV)的关键环节。去细胞瓣被认为是一种较理想的TEHV支架,本实验率先采用RGD肽(精-甘-天冬氨酸,Arg-Gly-Asp)表面修饰以促进细胞黏附,联合种植转化生长因子-β1(TGF-β1)基因转染细胞以促进细胞及细胞外基质(ECM)增生,观察两种生物活性分子对去细胞瓣体外构建TEHV的影响。 展开更多
关键词 转化生长因子-β1(TGF-β1) RGD肽 联合种植 组织工程瓣膜 细胞外基质(ECM) 组织工程心脏瓣膜 基因转染细胞 生物活性分子 hv支架 细胞黏附
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