The degree of processing is rarely considered an independent factor in the health effects of fruit juices and beverages(FJBs)consumption.In fact,the consumption of ultra-processed foods has been shown to pose health r...The degree of processing is rarely considered an independent factor in the health effects of fruit juices and beverages(FJBs)consumption.In fact,the consumption of ultra-processed foods has been shown to pose health risks.In this study,we first integrated 4 systems used to classify the degree of food processing and then classified FJBs into three major categories,low(minimal),moderate and high.Second,we compared the differences in attitudes towards FJBs in dietary guidelines.Third,we integrated the results of existing epidemiological surveys,randomized controlled trials,and animal experiments to explore the health risks associated with consuming FJBs.Deepening the processing of FJBs has been found to lead to an increased risk of diseases.Dietary pattern,nutrients,addition agents and consumer preferences may be influential factors.Finally,we investigated whether there were any changes in the health benefits of 100%fruit juices produced by different processing methods.In conclusion,minimally/moderately processed 100%fruit juices provide more health benefits than highly processed fruit beverages.The results support the need to consider the extent of FJBs processing in future studies to adjust official nutritional recommendations for beverage consumption.展开更多
Objective:The Delphi method was used to propose health effect evaluation indicators to assess foods for special medical purposes(FSMPs).This lays the foundation for the formation of a big data model for human health t...Objective:The Delphi method was used to propose health effect evaluation indicators to assess foods for special medical purposes(FSMPs).This lays the foundation for the formation of a big data model for human health testing,as well as a big data platform for the health and safety evaluation of special medical foods.Methods:The Delphi method was used to conduct two rounds of expert consultation on the constructed FSMP health effect evaluation indicators.Results:Ten major items were identified after two rounds of expert consultation.Among these,there were 10 primary entries,32 secondary entries,50 tertiary entries,and 28 quaternary entries.Conclusion:The complete list of evaluation indicators contains 10 entries,which can comprehensively and systematically monitor adverse reactions to the use of FSMPs.The present findings lay the foundation for a big data platform to evaluate the health and safety of special foods.展开更多
The frequency and scale of Harmful Algal Bloom (HAB) and marine algal toxin incidents have been increasing and spreading in the past two decades, causing damages to the marine environment and threatening human life th...The frequency and scale of Harmful Algal Bloom (HAB) and marine algal toxin incidents have been increasing and spreading in the past two decades, causing damages to the marine environment and threatening human life through contaminated seafood. To better understand the effect of HAB and marine algal toxins on marine environment and human health in China, this paper overviews HAB occurrence and marine algal toxin incidents, as well as their environmental and health effects in this country. HAB has been increasing rapidly along the Chinese coast since the 1970s, and at least 512 documented HAB events have occurred from 1952 to 2002 in the Chinese mainland. It has been found that PSP and DSP toxins are distributed widely along both the northern and southern Chinese coasts. The HAB and marine algal toxin events during the 1990s in China were summarized, showing that the HAB and algal toxins resulted in great damages to local fisheries, marine culture, quality of marine environment, and human health. Therefore, to protect the coastal environment and human health, attention to HAB and marine algal toxins is urgently needed from the environmental and epidemiologicalview.展开更多
Forest bathing trip is a short, leisurely visit to forest. In this study we determined the health effects of forest bathing trip on elderly patients with chronic obstructive pulmonary disease （COPD）. The patients we...Forest bathing trip is a short, leisurely visit to forest. In this study we determined the health effects of forest bathing trip on elderly patients with chronic obstructive pulmonary disease （COPD）. The patients were randomly divided into two groups. One group was sent to forest, and the other was sent to an urban area as control. Flow cytometry, ELISA, and profile of mood states （POMS） evaluation were performed. In the forest group,展开更多
The effects of airborne particulate matter （PM） trace elements on health are widely concerned nowadays. Many achievements have been made while many unknowns exist. This article reports the recent research progresses...The effects of airborne particulate matter （PM） trace elements on health are widely concerned nowadays. Many achievements have been made while many unknowns exist. This article reports the recent research progresses, describes the effects of exposure to PM trace elements on health epidemiological evidence, toxicology findings, and raises some questions for future studies.展开更多
A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR...A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR),-GT, GPT and AKP, were employed in the present survey among occupationally vinyl chloride (VC) exposed workers and inhabitants living in VC polluted area in a polyvinyl chloride (PVC) factory. The results showed that the serum lysozyme (S-LZM) activities in Group 3 (adult inhabitants exposed to 0.20 mg/m3 VC for at least 8 years), Group 2 (workers exposed to 4.1 mg/m3for at least 7 years occupationally), Group 1 (workers exposed to 25.7 mg/m3 for at least 2 years) were significantly higher than control. G-banding CA analysis showed that the total chromosome breakage rates in both Groups 1 and 2 were higher, but no difference existed between Group 3 and control. Only Group 1 was observed having higher SCEs, CA level and lower TcTR than control. AKP levels in Groups 1 and 2 were higher than control,but noγ-GT and GPT differences were found among groups. The study also suggests that G-banding CA analysis is more sensitive than CA and SCEs展开更多
In this work, the specific activities of natural radionuclides, namely <sup>238</sup>U series, <sup>232</sup>Th series and <sup>40</sup>K, have been measured in collected sedimentar...In this work, the specific activities of natural radionuclides, namely <sup>238</sup>U series, <sup>232</sup>Th series and <sup>40</sup>K, have been measured in collected sedimentary phosphate deposits samples from El-Hamraween, El-Quser and Safaga phosphate mines in Egypt. HPGe γ-spectrometry was used. This study was undertaken to estimate the radiation hazard indices in phosphate mining at the studied mines on their occupational workers, to establish correlation relationships between the some measured heavy metals such as As, Cd and Pb in blood workers and their concentration in phosphate rock ores and to determinate the biomarkers in the blood workers such as malondialdehyde (MDA) and superoxide dismutase (SOD). The phosphate mine sample of El-Hamrawein has the lowest activity concentration of <sup>226</sup>Ra, <sup>232</sup>Th and <sup>40</sup>K in comparison to the phosphate mine samples of El-Quseir and Safaga (El-Hamrawein kg<sup>-</sup>1</sup><sup></sup>, 122.4 to 188.3 Bq·kg<sup>-</sup>1</sup></sup> and 115.4 to 165.8 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. For <sup>232</sup>Th activity concentrations varied from 135.6 to 212.3 Bq·kg<sup>-</sup>1</sup></sup>, 112.8 to 167.4 Bq·kg<sup>-</sup>1</sup></sup> and 132.8 to 188.6 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. For <sup>40</sup>K activity concentrations varied from 225.2 to 312.8 Bq·kg<sup>-</sup>1</sup>, 168.7 to 268.9 Bq·kg<sup>-</sup>1</sup></sup> and 95.2 to 155.8 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. The workers of old ages have higher concentration of the investigated heavy metals than those of young ages. There is a good relation between the concentration of the investigated metals in phosphate mine samples and their concentration in blood of the occupational workers in these mines.展开更多
Xanthates are organic synthesized substances with a potentially wide range of applications. They may serve as essential components of many compounds or materials that also play a vital role in various industrial and s...Xanthates are organic synthesized substances with a potentially wide range of applications. They may serve as essential components of many compounds or materials that also play a vital role in various industrial and socio-economic processes. Addressing the question of the use of xanthates without considering their toxicity, and their decomposition process and products would be ecologically and healthily less sustainable. To date, related information is still dispersed and less known to the public. Therefore, this work provides a comprehensive overview of the existing information on the essentiality, fate, ecotoxicity, and health effects of xanthates and associated compounds. According to available information from scientific, technical, and professional circles, xanthates are diverse, usually with a carbon chain of two to six carbon atoms. They play a crucial role in the sectors of the mining and mineral processing industry, agriculture, wastewater treatment, metal protection, rubber vulcanization, the pharmaceutical industry, and medicine. Xanthates’ degradation under different factors and mechanisms, which determine their fate in the environment, leads to the formation of toxic substances, mainly carbon disulfide, carbonyl sulfide, hydrogen sulfide, and hydrogen peroxide. Xanthates and xanthates degradation products are seriously hazardous to humans, animals, soil and aquatic organisms, enzymatic system, etc. Simultaneous exposure to xanthates and metals results in the magnification or reduction of their toxicity level, depending on the exposed organisms. Such toxicological dimensions should attract more scientific and public attention for more safe production, use, storage, and disposal of xanthates. Due to the high affinity of xanthates for metal, xanthates-modified compounds are efficient metal chelating agents. Such a property should be explored to develop potentially low-cost and effective alternatives for metal removal and recovery from contaminated media. The same applies to developing appropriate methods for the evaluation and management of the simultaneous presence of xanthates and metals in the environment.展开更多
Introduction: Working in a noisy environment is a risk for employee hearing health. Standard threshold shift (STS) can be used as a screening method to detect early indications of hearing deterioration. Objective: To ...Introduction: Working in a noisy environment is a risk for employee hearing health. Standard threshold shift (STS) can be used as a screening method to detect early indications of hearing deterioration. Objective: To investigate health effects related to STS in motor compressor workers. Methods: A cross sectional study of 464 motor compressor workers was conducted including hearing health examination by audiometer, and noise level in the workplace was monitored. Workers who reported having hobbies relating to noise, e.g. gun shooting, or a personal history of disease relating to the ear were excluded. The relationship between health effects and workers with STS was studied. Results: There were more men 81.90% (aged range 31-40 years old) than women working for the company. The average continuous noise level in the workplace was 84.14 ± 5.21 dB(A). The study showed that working at the factory for more than 14 years (OR= 3.84, 95%CI 1.54-9.56) and being exposed to noise at least 8 hours a day (OR = 2.12, 95%CI = 1.02-4.40) effected to STS. Workers with STS showed significant communication difficulties (OR = 1.89, 95%CI = 1.03-3.49) and stress/nausea more than workers without STS (OR = 1.54, 95%CI = 0.90-2.65) although not statistically significant. Conclusions: Workers exposed to continuous noise in the motor compressor industry are at risk of STS. Duration of exposure to noise is a key factor in respect of harm to hearing health. STS could be used as a tool to screen workers who have hearing health problems.展开更多
The objective of this paper is the valuation of radiological health effects of Yatagan Power Plant. To this aim the radiation dose calculations are carried out for the population living within 80 km radius of the plan...The objective of this paper is the valuation of radiological health effects of Yatagan Power Plant. To this aim the radiation dose calculations are carried out for the population living within 80 km radius of the plant. The average of the maximum measured specific isotopes 238U, 232Th and 226Ra in the flying ash samples are considered as radioactive sources. Based on the dose calculations, first the stochastic health effects and then monetary health effects are estimated. The estimated total collective dose and economic value of the pre-dicted health effects are 0.3098 man Sv/y and 14791 US$/y respectively. The results obtained from the dose calculations are lower than the limits of International Commission of Radiation Protection (ICRP) and it does not pose any risk for public health. Monetary value of health risks is also negligible in comparison to the av-erage yearly sales revenue of the plant which is 250 million US$.展开更多
Introduction: Khat chewing is believed to be rapidly increasing worldwide. Worldwide, it is estimated that 10 million people consume khat daily. Khat chewing practice renders certain influence on physical and psycholo...Introduction: Khat chewing is believed to be rapidly increasing worldwide. Worldwide, it is estimated that 10 million people consume khat daily. Khat chewing practice renders certain influence on physical and psychological well being of the community and it can cause more serious adverse psychiatric, cardiovascular, dental and gastrointestinal effects. The recent sharp increase in khat consumption may not only affect the health of individuals but could also have serious socio-economic consequences. This study was conducted to assess prevalence of khat chewing practice, its associated factors and perceived health effects among communities in Dera woreda, Amhara region, Ethiopia 2013. Methods: Community-based cross-sectional study was conducted by using both quantitative and qualitative method of data. The sample size for quantitative was determined by using single population proportion formula and the households were selected by systematic sampling method and in the selected household, one respondent was selected by lottery among members of household aged 15 years and above. Data were collected by means of a pretested questionnaire;analysis was carried out using SPSS version 16. For the qualitative part ten in-depth interviews were conducted on purposely selected individuals and sample size for this method was determined through continuing to interview participants until no new information was obtained. Results: The response rate was 98.3%. Current prevalence of khat chewing practice was 17%. Males were more likely to chew khat (AOR, 18.53;95%CI, 7.20-47.66) compared to females. Muslims were more likely to chew khat (AOR, 4.34;95%CI, 2.07-9.11) compared to Orthodox Christians. Respondents who had family member chewing khat were more likely to chew khat (AOR, 2.67;95%CI, 1.15-6.21) compared to family member without a chewer. Among all the respondents, 92.8% perceived the health effects of khat chewing practice. Respondents who did not perceive health effect of khat were 5 times more likely to chew khat (AOR = 5.10, 95%CI;1.64-15.5) compared to those who perceived health effect of khat. Conclusions: The prevalence of khat chewing practice was 17% with high proportion of the khat chewers found in the urban setting. Sex, religion, residence, family chewing habit and perceived health effect were significantly associated factors with khat chewing practice. In this study 92.8% of the respondents perceived that khat chewing practice had harmful effects on health and the perceived health effects reported were sleeping disorder, hallucination, tooth staining, anxiety, and loss of appetite, depression, constipation, gastritis, hypertension and psychosis.展开更多
Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients...Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.展开更多
Objective: By the end of 2021, the aging rate of China’s population is 18.9%, and the prevalence rate of chronic diseases in the elderly population is increasing year by year, and chronic diseases have become the mai...Objective: By the end of 2021, the aging rate of China’s population is 18.9%, and the prevalence rate of chronic diseases in the elderly population is increasing year by year, and chronic diseases have become the main causes of death and health threats of Chinese residents. Therefore, how to manage this huge group well is crucial. This paper analyzes the value of health education in the process of health management for patients with chronic diseases. Methods: 102 patients with chronic diseases treated from January 2021 to December 2021 were divided into control group and experimental group by random number table method. The control group was given routine health management while the experimental group was given health education based on the control group, and the implementation effect was analyzed. Results: After management, the scores of chronic disease knowledge in the experimental group were significantly higher than those in the control group, and the dimensions of ESCA were higher than those in the control group, and P < 0.05;Conclusion: The implementation of health education in the process of chronic disease health management is helpful to improve patients’ self-care ability and better control disease progression.展开更多
Cultivated hawthorn(Crataegus pinnatifida var.major),the principal cultivated hawthorn species in China,is rich in phenolic compounds.These phytochemicals are considered essential bioactive ingredients in different or...Cultivated hawthorn(Crataegus pinnatifida var.major),the principal cultivated hawthorn species in China,is rich in phenolic compounds.These phytochemicals are considered essential bioactive ingredients in different organs of cultivated hawthorn,contributing to its health effects.However,there is lack of a comprehensive review that systematically summarizes the chemistry,health effects,and stability of phenolic substances.This review summarizes recent progress in the characterization,classification,and distribution of phenolic compounds in C.pinnatifida var.major,including procyanidins,flavonoids,phenolic acids,lignans,and others.Importantly,the stability of these compounds was found to be influenced by factors such as the hawthorn development process,postharvest storage,postharvest processing,and the gastrointestinal tract environment.Additionally,the health effects of phenolic compounds in cultivated hawthorn and their underlying mechanisms were discussed.This review provides valuable insights into the utilization of hawthorn resources and the development of the hawthorn industry.展开更多
The world’s climate,particularly in Africa,has changed substantially during the past few decades,contributed by several human activities.Africa is one of the continents that is most vulnerable to climate change globa...The world’s climate,particularly in Africa,has changed substantially during the past few decades,contributed by several human activities.Africa is one of the continents that is most vulnerable to climate change globally.Since the beginning of 2022,extreme weather events in Africa have affected about 19 million people and killed at least 4,000 individuals.Cyclones,floods,heatwaves,wildfires,droughts,and famine were among the severe weather occurrences.Natural disasters and extreme weather events brought on by climate change may compromise access to clean water,sanitation systems,and healthcare facilities,making people more vulnerable to a number of illnesses.Floods and drought can lead to both communicable and non-communicable diseases.The African population is more likely to experience more mental health disorders than before because of natural disasters,which result in the loss of property and sometimes loss of lives more frequently.We,therefore,call for an improved implementation of strategies to prevent the health effects of climate change so that the health of the people in Africa can be maintained.展开更多
Tartary buckwheat(Fagopyrum tataricum)is a well-known pseudocereal for its health and economic value.However,abundant antinutritional factors(ANFs)reduces its health benefits.As reported,germination can improve the nu...Tartary buckwheat(Fagopyrum tataricum)is a well-known pseudocereal for its health and economic value.However,abundant antinutritional factors(ANFs)reduces its health benefits.As reported,germination can improve the nutritional profile of grains.In this study,we systematically evaluate the safety of Tartary buckwheat seeds(TB)and Tartary buckwheat sprouts(TBS)used as high active ingredients.After evaluating nutrition levels,bioactive compounds and ANFs in TBS during germinating,5^(th)-day TBS were selected as the raw material.C57BL/6J mice were gavaged daily with distilled water,TB,or TBS for 6 weeks.The physiological indices related to ANFs were determined.Results showed that the TB intake tends to generate negative effects on the gut microbiota,and organs.Additionally,upon TB intake,the Fe^(3+)content in serum,trypsin activity in pancreas and jejunum decreased,while the cytokine,IgE,and histamine levels in serum,water content in faeces,cytokine levels in liver and jejunum increased.Conversely,TBS did not induce any obvious negative effects on the above relevant indices and showed better lipid-lowering effect.Altogether,TBS are safer and more effective as a raw material to produce the functional food for long-term consumption with the intention of preventing and treating hyperlipidaemia.展开更多
Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming t...Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].展开更多
Due to climate change,the heatwave has become a more serious public health threat with aging as an aggravating factor in recent years.There is a pressing need to detect the most effective prevention and response measu...Due to climate change,the heatwave has become a more serious public health threat with aging as an aggravating factor in recent years.There is a pressing need to detect the most effective prevention and response measures.However,the specific health effects of interventions have not been characterized on an individual scale.In this study,an intervention experiment was designed to explore the health effects of heat exposure at the individual level and assess the effects of different interventions based on a comprehensive health sensitivity index(CHSI)in Xinyi,China.Forty-one subjects were recruited randomly,and divided into one control group and three intervention groups.Interventions included education(Educate by lecturing,offering relative materials,and communication),subsidy support(offer subsidy to offset the cost of running air conditioning),and cooling-spray(install a piece of cooling-spray equipment in the yard).Results showed that systolic blood pressure(SBP)and deep sleep duration(DSD)were significantly affected by short-term heat exposure,and the effects could be alleviated by three types of interventions.The estimated CHSI indicated that the effective days of the education group were longer than other groups,while the lower CHSI of the subsidy group showed lower sensitivity than the control group.These findings provide feasible implementation strategies to optimize Heat-health action plans and evaluate the intervention performance.展开更多
Shijiazhuang is one of the cities in the North China Plain.In recent decades,this city has experienced high levels of fine particulate matter(PM_(2.5)),which have potentially significant effects on human health.In thi...Shijiazhuang is one of the cities in the North China Plain.In recent decades,this city has experienced high levels of fine particulate matter(PM_(2.5)),which have potentially significant effects on human health.In this study,the health effects of PM_(2.5)exposure in Shijiazhuang were estimated by applying an integrated exposure-response model.Premature mortality,years of life lost(YLL),and the mortality benefits linked to reduced levels of PM_(2.5)were quantified for the period 2015–2017.In 2015,2016,and 2017,cerebrovascular diseases caused the highest premature mortality(2432,2449,and 2483,respectively),followed by ischemic heart diseases(1391,1479,and 1493,respectively),lung cancer(639,660,and 639,respectively),and chronic obstructive pulmonary diseases(533,519,and 473,respectively).Notably,the total number of premature deaths caused by PM_(2.5)exposure in Shijiazhuang in 2015,2016,and 2017 were 4994,5107,and 5088,respectively.Moreover,the YLL in the same years were 47001,47880 and 47381,respectively.Interestingly,the YLL per 1000 females was lower than that per 1000 males.Finally,we noted that premature mortality and YLL decreased by 84.2%and 84.6%when the PM_(2.5)levels diminished to 10µg/m^(3).Overall,the results of this study improve our understanding of how high PM_(2.5)concentrations affect human health and suggest the application of more stringent measures in Shijiazhuang to alleviate the associated health risks.展开更多
基金funded by the National Natural Science Foundation Program of China(31901707)the 2115 Talent Development Program of China Agricultural University。
文摘The degree of processing is rarely considered an independent factor in the health effects of fruit juices and beverages(FJBs)consumption.In fact,the consumption of ultra-processed foods has been shown to pose health risks.In this study,we first integrated 4 systems used to classify the degree of food processing and then classified FJBs into three major categories,low(minimal),moderate and high.Second,we compared the differences in attitudes towards FJBs in dietary guidelines.Third,we integrated the results of existing epidemiological surveys,randomized controlled trials,and animal experiments to explore the health risks associated with consuming FJBs.Deepening the processing of FJBs has been found to lead to an increased risk of diseases.Dietary pattern,nutrients,addition agents and consumer preferences may be influential factors.Finally,we investigated whether there were any changes in the health benefits of 100%fruit juices produced by different processing methods.In conclusion,minimally/moderately processed 100%fruit juices provide more health benefits than highly processed fruit beverages.The results support the need to consider the extent of FJBs processing in future studies to adjust official nutritional recommendations for beverage consumption.
基金This research was supported by the National Key Research and Development Program of China(2019YFC1606400).
文摘Objective:The Delphi method was used to propose health effect evaluation indicators to assess foods for special medical purposes(FSMPs).This lays the foundation for the formation of a big data model for human health testing,as well as a big data platform for the health and safety evaluation of special medical foods.Methods:The Delphi method was used to conduct two rounds of expert consultation on the constructed FSMP health effect evaluation indicators.Results:Ten major items were identified after two rounds of expert consultation.Among these,there were 10 primary entries,32 secondary entries,50 tertiary entries,and 28 quaternary entries.Conclusion:The complete list of evaluation indicators contains 10 entries,which can comprehensively and systematically monitor adverse reactions to the use of FSMPs.The present findings lay the foundation for a big data platform to evaluate the health and safety of special foods.
基金This study was supported by National Basic Research Project No. 2001CB4097 NSFC Projects No.20177023+2 种基金 40076030 CAS Innovation Project No. KZCX2-206 Project of Shandong Province Science Committee No.012110115.
文摘The frequency and scale of Harmful Algal Bloom (HAB) and marine algal toxin incidents have been increasing and spreading in the past two decades, causing damages to the marine environment and threatening human life through contaminated seafood. To better understand the effect of HAB and marine algal toxins on marine environment and human health in China, this paper overviews HAB occurrence and marine algal toxin incidents, as well as their environmental and health effects in this country. HAB has been increasing rapidly along the Chinese coast since the 1970s, and at least 512 documented HAB events have occurred from 1952 to 2002 in the Chinese mainland. It has been found that PSP and DSP toxins are distributed widely along both the northern and southern Chinese coasts. The HAB and marine algal toxin events during the 1990s in China were summarized, showing that the HAB and algal toxins resulted in great damages to local fisheries, marine culture, quality of marine environment, and human health. Therefore, to protect the coastal environment and human health, attention to HAB and marine algal toxins is urgently needed from the environmental and epidemiologicalview.
基金supported by funds from the National Natural Science Foundation of China(31301139&31201040)funds from Science Technology Department of Zhejiang Province(2012C24005&2014C33130)+2 种基金Health Bureau of Zhejiang Province(11-CX01&2013ZDA002)Zhejiang Provincial Key Disciplinary Fields of Geriatrics Program
文摘Forest bathing trip is a short, leisurely visit to forest. In this study we determined the health effects of forest bathing trip on elderly patients with chronic obstructive pulmonary disease （COPD）. The patients were randomly divided into two groups. One group was sent to forest, and the other was sent to an urban area as control. Flow cytometry, ELISA, and profile of mood states （POMS） evaluation were performed. In the forest group,
文摘The effects of airborne particulate matter （PM） trace elements on health are widely concerned nowadays. Many achievements have been made while many unknowns exist. This article reports the recent research progresses, describes the effects of exposure to PM trace elements on health epidemiological evidence, toxicology findings, and raises some questions for future studies.
文摘A series of indicators, including serum lysozyme activity, G-banding chromosome aberration (G-banding CA) analysis, sister chromatid exchanges (SCEs), chromosome aberration (CA), T-lymphocyte transformation rate (TcTR),-GT, GPT and AKP, were employed in the present survey among occupationally vinyl chloride (VC) exposed workers and inhabitants living in VC polluted area in a polyvinyl chloride (PVC) factory. The results showed that the serum lysozyme (S-LZM) activities in Group 3 (adult inhabitants exposed to 0.20 mg/m3 VC for at least 8 years), Group 2 (workers exposed to 4.1 mg/m3for at least 7 years occupationally), Group 1 (workers exposed to 25.7 mg/m3 for at least 2 years) were significantly higher than control. G-banding CA analysis showed that the total chromosome breakage rates in both Groups 1 and 2 were higher, but no difference existed between Group 3 and control. Only Group 1 was observed having higher SCEs, CA level and lower TcTR than control. AKP levels in Groups 1 and 2 were higher than control,but noγ-GT and GPT differences were found among groups. The study also suggests that G-banding CA analysis is more sensitive than CA and SCEs
文摘In this work, the specific activities of natural radionuclides, namely <sup>238</sup>U series, <sup>232</sup>Th series and <sup>40</sup>K, have been measured in collected sedimentary phosphate deposits samples from El-Hamraween, El-Quser and Safaga phosphate mines in Egypt. HPGe γ-spectrometry was used. This study was undertaken to estimate the radiation hazard indices in phosphate mining at the studied mines on their occupational workers, to establish correlation relationships between the some measured heavy metals such as As, Cd and Pb in blood workers and their concentration in phosphate rock ores and to determinate the biomarkers in the blood workers such as malondialdehyde (MDA) and superoxide dismutase (SOD). The phosphate mine sample of El-Hamrawein has the lowest activity concentration of <sup>226</sup>Ra, <sup>232</sup>Th and <sup>40</sup>K in comparison to the phosphate mine samples of El-Quseir and Safaga (El-Hamrawein kg<sup>-</sup>1</sup><sup></sup>, 122.4 to 188.3 Bq·kg<sup>-</sup>1</sup></sup> and 115.4 to 165.8 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. For <sup>232</sup>Th activity concentrations varied from 135.6 to 212.3 Bq·kg<sup>-</sup>1</sup></sup>, 112.8 to 167.4 Bq·kg<sup>-</sup>1</sup></sup> and 132.8 to 188.6 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. For <sup>40</sup>K activity concentrations varied from 225.2 to 312.8 Bq·kg<sup>-</sup>1</sup>, 168.7 to 268.9 Bq·kg<sup>-</sup>1</sup></sup> and 95.2 to 155.8 Bq·kg<sup>-</sup>1</sup></sup> for Safaga, El-Quseir and El-Hamrawein, respectively. The workers of old ages have higher concentration of the investigated heavy metals than those of young ages. There is a good relation between the concentration of the investigated metals in phosphate mine samples and their concentration in blood of the occupational workers in these mines.
文摘Xanthates are organic synthesized substances with a potentially wide range of applications. They may serve as essential components of many compounds or materials that also play a vital role in various industrial and socio-economic processes. Addressing the question of the use of xanthates without considering their toxicity, and their decomposition process and products would be ecologically and healthily less sustainable. To date, related information is still dispersed and less known to the public. Therefore, this work provides a comprehensive overview of the existing information on the essentiality, fate, ecotoxicity, and health effects of xanthates and associated compounds. According to available information from scientific, technical, and professional circles, xanthates are diverse, usually with a carbon chain of two to six carbon atoms. They play a crucial role in the sectors of the mining and mineral processing industry, agriculture, wastewater treatment, metal protection, rubber vulcanization, the pharmaceutical industry, and medicine. Xanthates’ degradation under different factors and mechanisms, which determine their fate in the environment, leads to the formation of toxic substances, mainly carbon disulfide, carbonyl sulfide, hydrogen sulfide, and hydrogen peroxide. Xanthates and xanthates degradation products are seriously hazardous to humans, animals, soil and aquatic organisms, enzymatic system, etc. Simultaneous exposure to xanthates and metals results in the magnification or reduction of their toxicity level, depending on the exposed organisms. Such toxicological dimensions should attract more scientific and public attention for more safe production, use, storage, and disposal of xanthates. Due to the high affinity of xanthates for metal, xanthates-modified compounds are efficient metal chelating agents. Such a property should be explored to develop potentially low-cost and effective alternatives for metal removal and recovery from contaminated media. The same applies to developing appropriate methods for the evaluation and management of the simultaneous presence of xanthates and metals in the environment.
文摘Introduction: Working in a noisy environment is a risk for employee hearing health. Standard threshold shift (STS) can be used as a screening method to detect early indications of hearing deterioration. Objective: To investigate health effects related to STS in motor compressor workers. Methods: A cross sectional study of 464 motor compressor workers was conducted including hearing health examination by audiometer, and noise level in the workplace was monitored. Workers who reported having hobbies relating to noise, e.g. gun shooting, or a personal history of disease relating to the ear were excluded. The relationship between health effects and workers with STS was studied. Results: There were more men 81.90% (aged range 31-40 years old) than women working for the company. The average continuous noise level in the workplace was 84.14 ± 5.21 dB(A). The study showed that working at the factory for more than 14 years (OR= 3.84, 95%CI 1.54-9.56) and being exposed to noise at least 8 hours a day (OR = 2.12, 95%CI = 1.02-4.40) effected to STS. Workers with STS showed significant communication difficulties (OR = 1.89, 95%CI = 1.03-3.49) and stress/nausea more than workers without STS (OR = 1.54, 95%CI = 0.90-2.65) although not statistically significant. Conclusions: Workers exposed to continuous noise in the motor compressor industry are at risk of STS. Duration of exposure to noise is a key factor in respect of harm to hearing health. STS could be used as a tool to screen workers who have hearing health problems.
文摘The objective of this paper is the valuation of radiological health effects of Yatagan Power Plant. To this aim the radiation dose calculations are carried out for the population living within 80 km radius of the plant. The average of the maximum measured specific isotopes 238U, 232Th and 226Ra in the flying ash samples are considered as radioactive sources. Based on the dose calculations, first the stochastic health effects and then monetary health effects are estimated. The estimated total collective dose and economic value of the pre-dicted health effects are 0.3098 man Sv/y and 14791 US$/y respectively. The results obtained from the dose calculations are lower than the limits of International Commission of Radiation Protection (ICRP) and it does not pose any risk for public health. Monetary value of health risks is also negligible in comparison to the av-erage yearly sales revenue of the plant which is 250 million US$.
文摘Introduction: Khat chewing is believed to be rapidly increasing worldwide. Worldwide, it is estimated that 10 million people consume khat daily. Khat chewing practice renders certain influence on physical and psychological well being of the community and it can cause more serious adverse psychiatric, cardiovascular, dental and gastrointestinal effects. The recent sharp increase in khat consumption may not only affect the health of individuals but could also have serious socio-economic consequences. This study was conducted to assess prevalence of khat chewing practice, its associated factors and perceived health effects among communities in Dera woreda, Amhara region, Ethiopia 2013. Methods: Community-based cross-sectional study was conducted by using both quantitative and qualitative method of data. The sample size for quantitative was determined by using single population proportion formula and the households were selected by systematic sampling method and in the selected household, one respondent was selected by lottery among members of household aged 15 years and above. Data were collected by means of a pretested questionnaire;analysis was carried out using SPSS version 16. For the qualitative part ten in-depth interviews were conducted on purposely selected individuals and sample size for this method was determined through continuing to interview participants until no new information was obtained. Results: The response rate was 98.3%. Current prevalence of khat chewing practice was 17%. Males were more likely to chew khat (AOR, 18.53;95%CI, 7.20-47.66) compared to females. Muslims were more likely to chew khat (AOR, 4.34;95%CI, 2.07-9.11) compared to Orthodox Christians. Respondents who had family member chewing khat were more likely to chew khat (AOR, 2.67;95%CI, 1.15-6.21) compared to family member without a chewer. Among all the respondents, 92.8% perceived the health effects of khat chewing practice. Respondents who did not perceive health effect of khat were 5 times more likely to chew khat (AOR = 5.10, 95%CI;1.64-15.5) compared to those who perceived health effect of khat. Conclusions: The prevalence of khat chewing practice was 17% with high proportion of the khat chewers found in the urban setting. Sex, religion, residence, family chewing habit and perceived health effect were significantly associated factors with khat chewing practice. In this study 92.8% of the respondents perceived that khat chewing practice had harmful effects on health and the perceived health effects reported were sleeping disorder, hallucination, tooth staining, anxiety, and loss of appetite, depression, constipation, gastritis, hypertension and psychosis.
文摘Objective: To analyze the effect of health management on improving the awareness rate of disease prevention and treatment in patients with prehypertension, so as to provide guidance for clinical management of patients with prehypertension. Methods: 108 patients diagnosed with prehypertension in our hospital were divided into a control group and an experimental group. The control group was not given management measures, while the experimental group was given health management. The incidence of hypertension and cognition level of hypertension knowledge were compared between the two groups after management. Results: The incidence of hypertension in the experimental group was 7.41% lower than that in the control group 29.63%. The cognitive level of hypertension in the patients (66.54 ± 1.25) was significantly higher than that in the patients without health management (41.45 ± 2.45), and P < 0.05;Conclusion: For patients with prehypertension, the implementation of health management is helpful to improve their cognition of hypertension, master related prevention knowledge, and reduce the incidence of hypertension.
文摘Objective: By the end of 2021, the aging rate of China’s population is 18.9%, and the prevalence rate of chronic diseases in the elderly population is increasing year by year, and chronic diseases have become the main causes of death and health threats of Chinese residents. Therefore, how to manage this huge group well is crucial. This paper analyzes the value of health education in the process of health management for patients with chronic diseases. Methods: 102 patients with chronic diseases treated from January 2021 to December 2021 were divided into control group and experimental group by random number table method. The control group was given routine health management while the experimental group was given health education based on the control group, and the implementation effect was analyzed. Results: After management, the scores of chronic disease knowledge in the experimental group were significantly higher than those in the control group, and the dimensions of ESCA were higher than those in the control group, and P < 0.05;Conclusion: The implementation of health education in the process of chronic disease health management is helpful to improve patients’ self-care ability and better control disease progression.
基金supported by the Natural Science Foundation of Shandong Province(No.ZR2023QC228)the Key Research and Development Program of Zhejiang Province(No.2021C02001)+1 种基金the Shandong(Linyi)Institute of Modern Agriculture of Zhejiang University to Serve the Local Economic Development(Integration of Two Institutes)(No.ZDNY-2021-FWLY01004)the Fundamental Research Funds for the Central Universities(No.226-2022-00215),China.
文摘Cultivated hawthorn(Crataegus pinnatifida var.major),the principal cultivated hawthorn species in China,is rich in phenolic compounds.These phytochemicals are considered essential bioactive ingredients in different organs of cultivated hawthorn,contributing to its health effects.However,there is lack of a comprehensive review that systematically summarizes the chemistry,health effects,and stability of phenolic substances.This review summarizes recent progress in the characterization,classification,and distribution of phenolic compounds in C.pinnatifida var.major,including procyanidins,flavonoids,phenolic acids,lignans,and others.Importantly,the stability of these compounds was found to be influenced by factors such as the hawthorn development process,postharvest storage,postharvest processing,and the gastrointestinal tract environment.Additionally,the health effects of phenolic compounds in cultivated hawthorn and their underlying mechanisms were discussed.This review provides valuable insights into the utilization of hawthorn resources and the development of the hawthorn industry.
文摘The world’s climate,particularly in Africa,has changed substantially during the past few decades,contributed by several human activities.Africa is one of the continents that is most vulnerable to climate change globally.Since the beginning of 2022,extreme weather events in Africa have affected about 19 million people and killed at least 4,000 individuals.Cyclones,floods,heatwaves,wildfires,droughts,and famine were among the severe weather occurrences.Natural disasters and extreme weather events brought on by climate change may compromise access to clean water,sanitation systems,and healthcare facilities,making people more vulnerable to a number of illnesses.Floods and drought can lead to both communicable and non-communicable diseases.The African population is more likely to experience more mental health disorders than before because of natural disasters,which result in the loss of property and sometimes loss of lives more frequently.We,therefore,call for an improved implementation of strategies to prevent the health effects of climate change so that the health of the people in Africa can be maintained.
基金Supported by the Opening Project of Key Laboratory of Coarse Cereal Processing of Ministry of Agriculture and Rural AffairsSichuan Engineering and Technology Research Center of Coarse Cereal Industralization,Chengdu University(2022CC013)。
文摘Tartary buckwheat(Fagopyrum tataricum)is a well-known pseudocereal for its health and economic value.However,abundant antinutritional factors(ANFs)reduces its health benefits.As reported,germination can improve the nutritional profile of grains.In this study,we systematically evaluate the safety of Tartary buckwheat seeds(TB)and Tartary buckwheat sprouts(TBS)used as high active ingredients.After evaluating nutrition levels,bioactive compounds and ANFs in TBS during germinating,5^(th)-day TBS were selected as the raw material.C57BL/6J mice were gavaged daily with distilled water,TB,or TBS for 6 weeks.The physiological indices related to ANFs were determined.Results showed that the TB intake tends to generate negative effects on the gut microbiota,and organs.Additionally,upon TB intake,the Fe^(3+)content in serum,trypsin activity in pancreas and jejunum decreased,while the cytokine,IgE,and histamine levels in serum,water content in faeces,cytokine levels in liver and jejunum increased.Conversely,TBS did not induce any obvious negative effects on the above relevant indices and showed better lipid-lowering effect.Altogether,TBS are safer and more effective as a raw material to produce the functional food for long-term consumption with the intention of preventing and treating hyperlipidaemia.
文摘Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].
基金supported by the National Key Research and Development Program of China(No.2020YFC1807502)the National Natural Science Foundation of China(No.41822709)。
文摘Due to climate change,the heatwave has become a more serious public health threat with aging as an aggravating factor in recent years.There is a pressing need to detect the most effective prevention and response measures.However,the specific health effects of interventions have not been characterized on an individual scale.In this study,an intervention experiment was designed to explore the health effects of heat exposure at the individual level and assess the effects of different interventions based on a comprehensive health sensitivity index(CHSI)in Xinyi,China.Forty-one subjects were recruited randomly,and divided into one control group and three intervention groups.Interventions included education(Educate by lecturing,offering relative materials,and communication),subsidy support(offer subsidy to offset the cost of running air conditioning),and cooling-spray(install a piece of cooling-spray equipment in the yard).Results showed that systolic blood pressure(SBP)and deep sleep duration(DSD)were significantly affected by short-term heat exposure,and the effects could be alleviated by three types of interventions.The estimated CHSI indicated that the effective days of the education group were longer than other groups,while the lower CHSI of the subsidy group showed lower sensitivity than the control group.These findings provide feasible implementation strategies to optimize Heat-health action plans and evaluate the intervention performance.
基金Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control(KHK1906)Science and Technology Project of Hebei Education Department(ZD2020135)+3 种基金Overseas Talents Introduction Funded Project of Hebei Province(C20200308)National Innovation and Entrepreneurship Training Program for College Students(202010077001)Scientific Pre-Research Fund of Hebei GEO University in 2015(YK201501)the Young Talent Plan of Hebei Province 2016.
文摘Shijiazhuang is one of the cities in the North China Plain.In recent decades,this city has experienced high levels of fine particulate matter(PM_(2.5)),which have potentially significant effects on human health.In this study,the health effects of PM_(2.5)exposure in Shijiazhuang were estimated by applying an integrated exposure-response model.Premature mortality,years of life lost(YLL),and the mortality benefits linked to reduced levels of PM_(2.5)were quantified for the period 2015–2017.In 2015,2016,and 2017,cerebrovascular diseases caused the highest premature mortality(2432,2449,and 2483,respectively),followed by ischemic heart diseases(1391,1479,and 1493,respectively),lung cancer(639,660,and 639,respectively),and chronic obstructive pulmonary diseases(533,519,and 473,respectively).Notably,the total number of premature deaths caused by PM_(2.5)exposure in Shijiazhuang in 2015,2016,and 2017 were 4994,5107,and 5088,respectively.Moreover,the YLL in the same years were 47001,47880 and 47381,respectively.Interestingly,the YLL per 1000 females was lower than that per 1000 males.Finally,we noted that premature mortality and YLL decreased by 84.2%and 84.6%when the PM_(2.5)levels diminished to 10µg/m^(3).Overall,the results of this study improve our understanding of how high PM_(2.5)concentrations affect human health and suggest the application of more stringent measures in Shijiazhuang to alleviate the associated health risks.
