BACKGROUND Hospitalized and severely ill coronavirus disease 2019(COVID-19)patients necessitate prophylactic or therapeutic anticoagulation to minimize the risk of thrombosis at different sites.Life-threatening bleedi...BACKGROUND Hospitalized and severely ill coronavirus disease 2019(COVID-19)patients necessitate prophylactic or therapeutic anticoagulation to minimize the risk of thrombosis at different sites.Life-threatening bleeding complications include spontaneous iliopsoas hematoma,peritoneal bleeding,and extra-abdominal manifestations such as intracranial hemorrhage.CASE SUMMARY Bleeding in the abdominal wall results in less severe complications than seen with iliopsoas hematoma or peritoneal bleeding.In our case series of 9 patients,we present retroperitoneal and abdominal bleeding complications following anticoagulation in hospitalized COVID-19 patients with severe acute respiratory syndrome coronavirus 2 pneumonia.Contrast-enhanced computed tomography(CE-CT)is the best imaging modality for assessing hematoma secondary to anticoagulation and determines the therapeutic approach,whether interventional,surgical,or conservative management.CONCLUSION We present the role of CE-CT for rapid and precise localization of the bleeding site and prognostic counseling.Finally,we provide a brief review of the literature.展开更多
BACKGROUND The definition of diabetic foot syndrome(DFS)varies depending on the location and resources.Few classifications are available according to the indication.DF ulcers and vitamin D deficiency are common diseas...BACKGROUND The definition of diabetic foot syndrome(DFS)varies depending on the location and resources.Few classifications are available according to the indication.DF ulcers and vitamin D deficiency are common diseases among patients with diabetes.Previous literature has shown an association between DF ulcer(DFU)and vitamin D deficiency.However,the available meta-0analysis was limited by substantial bias.AIM To investigate the association between DFUs and vitamin D levels.METHODS We searched PubMed,MEDLINE,and Cochrane Library,EBSCO,and Google Scholar for studies comparing vitamin D levels and DF.The keywords DFU,DFS,diabetic septic foot,vitamin D level,25-hydroxy vitamin D,vitamin D status,and vitamin D deficiency were used.The search engine was set for articles published during the period from inception to October 2022.A predetermined table was used to collect the study information.RESULTS Vitamin D level was lower among patients with DFU compared to their counterparts[odds ratio(OR):-5.77;95%confidence interval(CI):-7.87 to-3.66;χ2 was 84.62,mean difference,9;I2 for heterogeneity,89%;P<0.001 and P for overall effect<0.001].The results remained robust for hospitalized patients(OR:-6.3295%CI:-11.66 to-0.97;χ2 was 19.39;mean difference,2;I2 for heterogeneity,90%;P=0.02).CONCLUSION Vitamin D was lower among outpatients and hospitalized patients with DFUs.Further larger randomized controlled trials are needed.展开更多
Objective:To explore the current status and influencing factors of quality of life in patients with lung cancer after surgery in a tertiary hospital in Hainan province.Methods:To investigate the influencing factors of...Objective:To explore the current status and influencing factors of quality of life in patients with lung cancer after surgery in a tertiary hospital in Hainan province.Methods:To investigate the influencing factors of quality of life of lung cancer patients after surgery in a tertiary hospital in Hainan province by cross‑sectional survey method.Results:The scores of insomnia,appetite loss,constipation and pain in 186 lung cancer patients after surgery in a tertiary hospital in Hainan Province were significantly higher than the reference value.Multiple linear regression analysis showed that older patients(>60 years)had lower scores in physical function domain(β=-0.193),and female patients had more appetite loss symptoms(β=0.245).Compared with other minority ethnic groups,Han ethnic group had lower scores in role function domain(β=0.179),more severe fatigue symptoms(β=-0.162),and higher general health level(β=0.166).Patients with employee medical insurance had lower scores of emotional function(β=0.194),cognitive function(β=0.281),the lowest score in social function(β=0.188),and severe pain in other parts(β=-0.227).Smokers had less cough symptoms(β=0.175)and more arm and shoulder pain symptoms(β=-0.21)than non‑smokers.Patients with secondhand smoke exposure had lower cognitive function scores(β=-0.158)and more obvious symptoms of oral ulcer(β=0.185).Patients who drank alcohol frequently(drinking frequency>1 time/day)had more severe cough symptoms(β=0.27).Patients with small number of children(0‑1)had milder cough symptoms(β=0.178).Patients who did not understand the disease had obvious symptoms of arm and shoulder pain(β=0.151).Patients with early pathological stage(stageⅠ‑Ⅱ)had more severe shortness of breath(β=-0.159)and pain(β=-0.181).The symptoms of appetite loss were more obvious in patients living in cities(β=0.192).The symptoms of peripheral neuropathy were more obvious(β=0.174).Patients who often consumed pickulated food had severe pain symptoms(β=-0.219),and pain in other parts was obvious(β=-0.149).Male patients had obvious alopecia symptoms(β=-0.306).Conclusion:Age,ethnicity,residence,type of medical insurance,number of children,pathological stage of lung cancer,smoking,second‑hand smoke exposure,alcohol consumption,and frequent consumption of pickled food were related to the quality of life of lung cancer patients in hospital after surgery.Medical staff and family members should pay attention to the emotional communication of patients during the treatment of lung cancer patients in hospital after surgery.Patients should avoid exposure to smoking,alcohol and second‑hand smoke,and reduce consumption of pickled food.展开更多
Hypoglycemia occurred on hospitalized patients would result in severe complications.So we monitored the blood glucose of hospitalized patients with diabetes in 14 clinical departments from January to December 2013.Tot...Hypoglycemia occurred on hospitalized patients would result in severe complications.So we monitored the blood glucose of hospitalized patients with diabetes in 14 clinical departments from January to December 2013.Totally 105728 cases of blood glucose were monitored and 1374 cases of hypoglycemia were detected.The incidence of hypoglycemia was 1.29%.Among which,317 cases of severe hypoglycemia were detected and the incidence of severe hypoglycemia was 0.29%.The peak periods of hypoglycemia were 0:00~2:00,22:00~24:00,2:00~4:00,8:00~10:00 and 10:00~12:00.The symptomatic hypoglycemia accounted for 47.01%,The asymptomatic hypoglycemia accounted for 52.98%.The incidence of hypoglycemia was 1.49%in medical departments and 0.87%in surgical departments.It is suggested to be vigilant of high risk periods of hypoglycemia,detect and treat asymptomatic hypoglycemia timely and rationally administer antidiabetics to prevent hypoglycemia.展开更多
Objective To study the relationship between serum uric acid and insulin resistance in type 2 diabetic patients.Methods A total of 728 middle-aged and elderly type 2 diabetic patients were recruited and the anthropomet...Objective To study the relationship between serum uric acid and insulin resistance in type 2 diabetic patients.Methods A total of 728 middle-aged and elderly type 2 diabetic patients were recruited and the anthropometric,clinical and biochemical parameters and展开更多
Objective:To identify the febrile characteristics and clinical presentations associated with fatality in hospitalized adult patients with dengue virus(DENV)infections.Methods:A total of 289 adult hospitalized patients...Objective:To identify the febrile characteristics and clinical presentations associated with fatality in hospitalized adult patients with dengue virus(DENV)infections.Methods:A total of 289 adult hospitalized patients with laboratoryconfirmed DENV infections were examined,of which 22 were fatal and 267 were non-fatal.A comparison of the clinical and laboratory characteristics was retrospectively conducted of the deceased and surviving individuals.Multivariate logistic regression and receiver operating characteristic curve analysis were performed to identify predictors of fatality.Results:Fatal patients exhibited significantly more comorbidities,particularly renal and cardiac comorbidities,and they were,in general,older than control individuals(P<0.0001).The results of logistic regression analysis showed that febrile duration of less than four days before arriving in the Emergency Department(OR=5.34;95%CI:1.39–20.6),episode of hypotension in the Emergency Department(OR=6.95;95%CI:2.40–20.1),and comorbidity with congestive heart failure(OR=11.26;95%CI:2.31–54.79)were all significantly associated with inpatient fatality due to DENV infection.The ROC curve analysis indicated that the final prognostic model yielded an area under the curve of 0.87(95%CI:0.79–0.97)for fatality.Conclusions:The aforementioned clinical findings may help clinicians predict fatality among adult inpatients with DENV infection.展开更多
BACKGROUND The variability of metabolic biomarkers has been determined to provide incremental prognosis information,but the implications of electrolyte variability remained unclear.METHODS We investigate the relations...BACKGROUND The variability of metabolic biomarkers has been determined to provide incremental prognosis information,but the implications of electrolyte variability remained unclear.METHODS We investigate the relationships between electrolyte fluctuation and outcomes in survivors of acute myocardial infarction(n=4386).Ion variability was calculated as the coefficient of variation,standard deviation,variability independent of the mean(VIM)and range.Hazard ratios(HR)were estimated using the multivariable-adjusted Cox proportional regression method.RESULTS During a median follow-up of 12 months,161(3.7%)patients died,and heart failure occurred in 550(12.5%)participants after discharge,respectively.Compared with the bottom quartile,the highest quartile potassium VIM was associated with increased risks of all-cause mortality(HR=2.35,95%CI:1.36–4.06)and heart failure(HR=1.32,95%CI:1.01–1.72)independent of cardiac troponin I(c Tn I),N terminal pro B type natriuretic peptide(NT-pro BNP),infarction site,mean potassium and other traditional factors,while those associations across sodium VIM quartiles were insignificant.Similar trend remains across the strata of variability by other three indices.These associations were consistent after excluding patients with any extreme electrolyte value and diuretic use.CONCLUSIONS Higher potassium variability but not sodium variability was associated with adverse outcomes post-infarction.Our findings highlight that potassium variability remains a robust risk factor for mortality regardless of clinical dysnatraemia and dyskalaemia.展开更多
Objective To investigate the infection rate of hepatitis C virus among the ambulatory patients and in-patients of a tertiary teaching hospital,and study the demographic factors related to the prevalence of hepatitis C...Objective To investigate the infection rate of hepatitis C virus among the ambulatory patients and in-patients of a tertiary teaching hospital,and study the demographic factors related to the prevalence of hepatitis C virus infection.Methods All patients tested for hepatitis C virus antibody from July 2008 to July 2009 in Peking Union Medical College Hospital were enrolled in this cross-sectional analysis.The prevalence of hepatitis C virus infection was compared according to age,gender,and departments,respectively.Among patients with positive serology hepatitis C virus marker,the positivity of hepatitis C virus RNA was analysed.Results Among 29 896 subjects included,the hepatitis C virus antibody of 494 patients were positive(1.7%).When patients were divided into 9 age groups,the age specific prevalence of hepatitis C virus antibody were0.2%,1.7%,1.2%,1.1%,1.5%,1.9%,2.6%,2.4%and 2%,respectively.The prevalence of hepatitis C virus antibody in non-surgical department and surgical department was 3%and 1%,respectively.The prevalence of hepatitis C virus antibody of males was higher than that of the females.Total of 194 patients with positive hepatitis C virus antibody were tested for hepatitis C virus RNA,the RNA level of 113 patients(58.2%)were higher than the low detection limit.Conclusions The prevalence of hepatitis C virus antibody was relatively high among patients of general tertiary hospital.Age group of 60-69,males and patients in non-surgical departments were factors associated with high rate of hepatitis C virus infection.展开更多
The purpose of this study is to explore Jordanian nurses’ knowledge and attitudes regarding pain assessment, and barriers to intervention at different hospitals representing health care sectors in Jordan. A descripti...The purpose of this study is to explore Jordanian nurses’ knowledge and attitudes regarding pain assessment, and barriers to intervention at different hospitals representing health care sectors in Jordan. A descriptive cross-sectional design was used in this study utilizing self-administered questionnaires to collect data from nurses working in public, University-affiliated, and private hospitals located on the north, mid, and south of Jordan using Nurses’ Knowledge and Attitudes Survey Regarding Pain, (n = 439). The mean of total correct answers on the 32 knowledge questions was 13.39 (SD = 4.31). Nurse-related barriers to effective pain management include patient history of alcohol abuse or drug addiction, and nursing staff reluctant to contact physician for analgesic order. Nurses working in surgical units, employed at private hospitals, holding a master degree, or who attended educational course or program scored significantly higher than other nurses. The results demonstrated knowledge deficit and attitude and that nurses underestimated and undertreated patients’ pain. Serious efforts should be taken in nursing schools and hospitals to prepare nurses and equip them with comprehensive knowledge tools to assess and manage pain appropriately.展开更多
ON an autumn afternoon, I walked into the well-known De’an Hospital in Changzhou, Jiangsu Province, and could hardly believe this neat and tidy compound was a mental hospital. The facility is famous for its methods f...ON an autumn afternoon, I walked into the well-known De’an Hospital in Changzhou, Jiangsu Province, and could hardly believe this neat and tidy compound was a mental hospital. The facility is famous for its methods for the prevention of mental illness and home therapy, which was initiated by Gu Hanping, president of the hospital. Gu, 39, has been praised by authoritative persons of the World Health Organization as the "Changzhou Mode in China." After I met this quick-minded woman, I no longer was surprised by the stories that had been展开更多
Objective:To determine the extended-spectrum beta-lactamase(ESBL)production and prevalence of bla_(CTX-M-1),bla_(SHV)and bla_(TEM)genes among uropathogenic Escherichia coli(UPEC)isolates from 3 military hospitals of T...Objective:To determine the extended-spectrum beta-lactamase(ESBL)production and prevalence of bla_(CTX-M-1),bla_(SHV)and bla_(TEM)genes among uropathogenic Escherichia coli(UPEC)isolates from 3 military hospitals of Tehran during 2015-2016.Methods:One-hundred and eleven isolates were adopted.The antibiotic susceptibility testing was conducted according to Clinical and Laboratory Standards Institute guidelines.The combine disk was used for phenotypic ESBL production.The ceftazidime MIC was conducted with the micro-broth dilution test.The PCR assay was used to detect the bla_(CTX-M-1),bla_(SHV)and bla_(TEM)genes.Results:In the broth microdilution method,103(92.7%)isolates showed minimal inhibitory concentration(MIC)≥1μg/mL,and also in the combined disk method,89(80.1%of all)were ESBL positive.On the other hand,among 91 ceftazidime resistant isolates,86(77.4%of all)were ESBL positive.The difference between the two methods for ESBL confirmation was not significant.The result of MIC was similar to the disk diffusion method in the detection of phenotypic ESBL production.Among ESBL producer isolates,the prevalence of bla_(CTX-M-1),bla_(SHV)and bla_(TEM)was 77.4%(n=86),47.4%(n=53)and 2.4%(n=2),respectively.These genes were amplified in a wide range MIC of ceftazidime.Conclusions:The prevalence of multi-drug resistant UPEC and ESBL positive isolates was high in military hospitals.The majority of UPEC isolates amplified bla_(CTX-M-I)and bla_(SHV)typeβ-lactamase genes.One-third of isolates were positive in presence of both these genes.There was no relation between ceftazidime MIC and presence of beta-lactamase genes.展开更多
文摘BACKGROUND Hospitalized and severely ill coronavirus disease 2019(COVID-19)patients necessitate prophylactic or therapeutic anticoagulation to minimize the risk of thrombosis at different sites.Life-threatening bleeding complications include spontaneous iliopsoas hematoma,peritoneal bleeding,and extra-abdominal manifestations such as intracranial hemorrhage.CASE SUMMARY Bleeding in the abdominal wall results in less severe complications than seen with iliopsoas hematoma or peritoneal bleeding.In our case series of 9 patients,we present retroperitoneal and abdominal bleeding complications following anticoagulation in hospitalized COVID-19 patients with severe acute respiratory syndrome coronavirus 2 pneumonia.Contrast-enhanced computed tomography(CE-CT)is the best imaging modality for assessing hematoma secondary to anticoagulation and determines the therapeutic approach,whether interventional,surgical,or conservative management.CONCLUSION We present the role of CE-CT for rapid and precise localization of the bleeding site and prognostic counseling.Finally,we provide a brief review of the literature.
文摘BACKGROUND The definition of diabetic foot syndrome(DFS)varies depending on the location and resources.Few classifications are available according to the indication.DF ulcers and vitamin D deficiency are common diseases among patients with diabetes.Previous literature has shown an association between DF ulcer(DFU)and vitamin D deficiency.However,the available meta-0analysis was limited by substantial bias.AIM To investigate the association between DFUs and vitamin D levels.METHODS We searched PubMed,MEDLINE,and Cochrane Library,EBSCO,and Google Scholar for studies comparing vitamin D levels and DF.The keywords DFU,DFS,diabetic septic foot,vitamin D level,25-hydroxy vitamin D,vitamin D status,and vitamin D deficiency were used.The search engine was set for articles published during the period from inception to October 2022.A predetermined table was used to collect the study information.RESULTS Vitamin D level was lower among patients with DFU compared to their counterparts[odds ratio(OR):-5.77;95%confidence interval(CI):-7.87 to-3.66;χ2 was 84.62,mean difference,9;I2 for heterogeneity,89%;P<0.001 and P for overall effect<0.001].The results remained robust for hospitalized patients(OR:-6.3295%CI:-11.66 to-0.97;χ2 was 19.39;mean difference,2;I2 for heterogeneity,90%;P=0.02).CONCLUSION Vitamin D was lower among outpatients and hospitalized patients with DFUs.Further larger randomized controlled trials are needed.
基金Hainan Province Key R&D Plan Project(No.Social Development)(No.ZDYF2021SHFZ086)Hainan Natural Science Foundation Youth Fund Project(No.820QN268)。
文摘Objective:To explore the current status and influencing factors of quality of life in patients with lung cancer after surgery in a tertiary hospital in Hainan province.Methods:To investigate the influencing factors of quality of life of lung cancer patients after surgery in a tertiary hospital in Hainan province by cross‑sectional survey method.Results:The scores of insomnia,appetite loss,constipation and pain in 186 lung cancer patients after surgery in a tertiary hospital in Hainan Province were significantly higher than the reference value.Multiple linear regression analysis showed that older patients(>60 years)had lower scores in physical function domain(β=-0.193),and female patients had more appetite loss symptoms(β=0.245).Compared with other minority ethnic groups,Han ethnic group had lower scores in role function domain(β=0.179),more severe fatigue symptoms(β=-0.162),and higher general health level(β=0.166).Patients with employee medical insurance had lower scores of emotional function(β=0.194),cognitive function(β=0.281),the lowest score in social function(β=0.188),and severe pain in other parts(β=-0.227).Smokers had less cough symptoms(β=0.175)and more arm and shoulder pain symptoms(β=-0.21)than non‑smokers.Patients with secondhand smoke exposure had lower cognitive function scores(β=-0.158)and more obvious symptoms of oral ulcer(β=0.185).Patients who drank alcohol frequently(drinking frequency>1 time/day)had more severe cough symptoms(β=0.27).Patients with small number of children(0‑1)had milder cough symptoms(β=0.178).Patients who did not understand the disease had obvious symptoms of arm and shoulder pain(β=0.151).Patients with early pathological stage(stageⅠ‑Ⅱ)had more severe shortness of breath(β=-0.159)and pain(β=-0.181).The symptoms of appetite loss were more obvious in patients living in cities(β=0.192).The symptoms of peripheral neuropathy were more obvious(β=0.174).Patients who often consumed pickulated food had severe pain symptoms(β=-0.219),and pain in other parts was obvious(β=-0.149).Male patients had obvious alopecia symptoms(β=-0.306).Conclusion:Age,ethnicity,residence,type of medical insurance,number of children,pathological stage of lung cancer,smoking,second‑hand smoke exposure,alcohol consumption,and frequent consumption of pickled food were related to the quality of life of lung cancer patients in hospital after surgery.Medical staff and family members should pay attention to the emotional communication of patients during the treatment of lung cancer patients in hospital after surgery.Patients should avoid exposure to smoking,alcohol and second‑hand smoke,and reduce consumption of pickled food.
文摘Hypoglycemia occurred on hospitalized patients would result in severe complications.So we monitored the blood glucose of hospitalized patients with diabetes in 14 clinical departments from January to December 2013.Totally 105728 cases of blood glucose were monitored and 1374 cases of hypoglycemia were detected.The incidence of hypoglycemia was 1.29%.Among which,317 cases of severe hypoglycemia were detected and the incidence of severe hypoglycemia was 0.29%.The peak periods of hypoglycemia were 0:00~2:00,22:00~24:00,2:00~4:00,8:00~10:00 and 10:00~12:00.The symptomatic hypoglycemia accounted for 47.01%,The asymptomatic hypoglycemia accounted for 52.98%.The incidence of hypoglycemia was 1.49%in medical departments and 0.87%in surgical departments.It is suggested to be vigilant of high risk periods of hypoglycemia,detect and treat asymptomatic hypoglycemia timely and rationally administer antidiabetics to prevent hypoglycemia.
文摘Objective To study the relationship between serum uric acid and insulin resistance in type 2 diabetic patients.Methods A total of 728 middle-aged and elderly type 2 diabetic patients were recruited and the anthropometric,clinical and biochemical parameters and
基金supported by National Cheng Kung University Hospital(NCKUH-10505033)
文摘Objective:To identify the febrile characteristics and clinical presentations associated with fatality in hospitalized adult patients with dengue virus(DENV)infections.Methods:A total of 289 adult hospitalized patients with laboratoryconfirmed DENV infections were examined,of which 22 were fatal and 267 were non-fatal.A comparison of the clinical and laboratory characteristics was retrospectively conducted of the deceased and surviving individuals.Multivariate logistic regression and receiver operating characteristic curve analysis were performed to identify predictors of fatality.Results:Fatal patients exhibited significantly more comorbidities,particularly renal and cardiac comorbidities,and they were,in general,older than control individuals(P<0.0001).The results of logistic regression analysis showed that febrile duration of less than four days before arriving in the Emergency Department(OR=5.34;95%CI:1.39–20.6),episode of hypotension in the Emergency Department(OR=6.95;95%CI:2.40–20.1),and comorbidity with congestive heart failure(OR=11.26;95%CI:2.31–54.79)were all significantly associated with inpatient fatality due to DENV infection.The ROC curve analysis indicated that the final prognostic model yielded an area under the curve of 0.87(95%CI:0.79–0.97)for fatality.Conclusions:The aforementioned clinical findings may help clinicians predict fatality among adult inpatients with DENV infection.
基金supported by the National Key R&D Program of China(No.2016YFC1301100)National Natural Science Foundation of China(No.81827806,81870353,31771241)Key Laboratory of Myocardial Ischemia,Ministry of Education(No.KF201903)。
文摘BACKGROUND The variability of metabolic biomarkers has been determined to provide incremental prognosis information,but the implications of electrolyte variability remained unclear.METHODS We investigate the relationships between electrolyte fluctuation and outcomes in survivors of acute myocardial infarction(n=4386).Ion variability was calculated as the coefficient of variation,standard deviation,variability independent of the mean(VIM)and range.Hazard ratios(HR)were estimated using the multivariable-adjusted Cox proportional regression method.RESULTS During a median follow-up of 12 months,161(3.7%)patients died,and heart failure occurred in 550(12.5%)participants after discharge,respectively.Compared with the bottom quartile,the highest quartile potassium VIM was associated with increased risks of all-cause mortality(HR=2.35,95%CI:1.36–4.06)and heart failure(HR=1.32,95%CI:1.01–1.72)independent of cardiac troponin I(c Tn I),N terminal pro B type natriuretic peptide(NT-pro BNP),infarction site,mean potassium and other traditional factors,while those associations across sodium VIM quartiles were insignificant.Similar trend remains across the strata of variability by other three indices.These associations were consistent after excluding patients with any extreme electrolyte value and diuretic use.CONCLUSIONS Higher potassium variability but not sodium variability was associated with adverse outcomes post-infarction.Our findings highlight that potassium variability remains a robust risk factor for mortality regardless of clinical dysnatraemia and dyskalaemia.
文摘Objective To investigate the infection rate of hepatitis C virus among the ambulatory patients and in-patients of a tertiary teaching hospital,and study the demographic factors related to the prevalence of hepatitis C virus infection.Methods All patients tested for hepatitis C virus antibody from July 2008 to July 2009 in Peking Union Medical College Hospital were enrolled in this cross-sectional analysis.The prevalence of hepatitis C virus infection was compared according to age,gender,and departments,respectively.Among patients with positive serology hepatitis C virus marker,the positivity of hepatitis C virus RNA was analysed.Results Among 29 896 subjects included,the hepatitis C virus antibody of 494 patients were positive(1.7%).When patients were divided into 9 age groups,the age specific prevalence of hepatitis C virus antibody were0.2%,1.7%,1.2%,1.1%,1.5%,1.9%,2.6%,2.4%and 2%,respectively.The prevalence of hepatitis C virus antibody in non-surgical department and surgical department was 3%and 1%,respectively.The prevalence of hepatitis C virus antibody of males was higher than that of the females.Total of 194 patients with positive hepatitis C virus antibody were tested for hepatitis C virus RNA,the RNA level of 113 patients(58.2%)were higher than the low detection limit.Conclusions The prevalence of hepatitis C virus antibody was relatively high among patients of general tertiary hospital.Age group of 60-69,males and patients in non-surgical departments were factors associated with high rate of hepatitis C virus infection.
文摘The purpose of this study is to explore Jordanian nurses’ knowledge and attitudes regarding pain assessment, and barriers to intervention at different hospitals representing health care sectors in Jordan. A descriptive cross-sectional design was used in this study utilizing self-administered questionnaires to collect data from nurses working in public, University-affiliated, and private hospitals located on the north, mid, and south of Jordan using Nurses’ Knowledge and Attitudes Survey Regarding Pain, (n = 439). The mean of total correct answers on the 32 knowledge questions was 13.39 (SD = 4.31). Nurse-related barriers to effective pain management include patient history of alcohol abuse or drug addiction, and nursing staff reluctant to contact physician for analgesic order. Nurses working in surgical units, employed at private hospitals, holding a master degree, or who attended educational course or program scored significantly higher than other nurses. The results demonstrated knowledge deficit and attitude and that nurses underestimated and undertreated patients’ pain. Serious efforts should be taken in nursing schools and hospitals to prepare nurses and equip them with comprehensive knowledge tools to assess and manage pain appropriately.
文摘ON an autumn afternoon, I walked into the well-known De’an Hospital in Changzhou, Jiangsu Province, and could hardly believe this neat and tidy compound was a mental hospital. The facility is famous for its methods for the prevention of mental illness and home therapy, which was initiated by Gu Hanping, president of the hospital. Gu, 39, has been praised by authoritative persons of the World Health Organization as the "Changzhou Mode in China." After I met this quick-minded woman, I no longer was surprised by the stories that had been
基金Supported by AJA University of Medical Sciences of Iran(Grant No.1649546/6743,2015).
文摘Objective:To determine the extended-spectrum beta-lactamase(ESBL)production and prevalence of bla_(CTX-M-1),bla_(SHV)and bla_(TEM)genes among uropathogenic Escherichia coli(UPEC)isolates from 3 military hospitals of Tehran during 2015-2016.Methods:One-hundred and eleven isolates were adopted.The antibiotic susceptibility testing was conducted according to Clinical and Laboratory Standards Institute guidelines.The combine disk was used for phenotypic ESBL production.The ceftazidime MIC was conducted with the micro-broth dilution test.The PCR assay was used to detect the bla_(CTX-M-1),bla_(SHV)and bla_(TEM)genes.Results:In the broth microdilution method,103(92.7%)isolates showed minimal inhibitory concentration(MIC)≥1μg/mL,and also in the combined disk method,89(80.1%of all)were ESBL positive.On the other hand,among 91 ceftazidime resistant isolates,86(77.4%of all)were ESBL positive.The difference between the two methods for ESBL confirmation was not significant.The result of MIC was similar to the disk diffusion method in the detection of phenotypic ESBL production.Among ESBL producer isolates,the prevalence of bla_(CTX-M-1),bla_(SHV)and bla_(TEM)was 77.4%(n=86),47.4%(n=53)and 2.4%(n=2),respectively.These genes were amplified in a wide range MIC of ceftazidime.Conclusions:The prevalence of multi-drug resistant UPEC and ESBL positive isolates was high in military hospitals.The majority of UPEC isolates amplified bla_(CTX-M-I)and bla_(SHV)typeβ-lactamase genes.One-third of isolates were positive in presence of both these genes.There was no relation between ceftazidime MIC and presence of beta-lactamase genes.
