Introduction: Laryngeal carcinoma accounts for 13.9% of head and neck tumors, and squamous cell carcinoma is the main pathological type. At present, the treatment of laryngeal cancer is mainly surgical treatment or po...Introduction: Laryngeal carcinoma accounts for 13.9% of head and neck tumors, and squamous cell carcinoma is the main pathological type. At present, the treatment of laryngeal cancer is mainly surgical treatment or postoperative radiotherapy. The surgery is delicate, complex, time-consuming and traumatic. Postoperative patients are prone to dysphagia, leading to an increase in the incidence of malnutrition. Malnutrition can cause a series of negative effects, including weight loss, increased incidence of infection, reduced tolerance of anti-tumor treatment, and extended length of hospital stay. Therefore, how to effectively improve the nutritional status of laryngeal cancer patients through nursing intervention has become an important topic of nursing research. Objective: Investigate the effect of individualized nutrition intervention care combined with swallowing training on postoperative nutritional status in patients with laryngeal cancer. Methods: A total of 120 consecutive patients who underwent laryngeal surgery at our hospital for the first time between May 2018 and May 2021 were selected for the study and equally divided into the control group and the study group by the random number table method, with 60 patients in each group. Patients in the control group were given swallowing function training and health counseling, and the study group adopted individualized nutrition intervention care based on the control group. The nutritional status, swallowing function, and quality of life (QOL) of the patients were assessed using the Patient-generated Subjective Global Assessment (PG-SGA), MD Anderson Dysphagia Inventory (MDADI), and Quality of Life Questionnaire-Core30 (QLQ-C30) before the intervention and three months after the intervention. Results: Before the intervention, the scores of MDADI, PG-SGA, and QLQ-C30 were not significantly different between the two groups (P > 0.05), and three months after the intervention, the scores of MDADI and QLQ-C30 increased and the score of PG-SGA decreased in the study group, with significant differences (P 0.05). At three months after the intervention, patients in the study group had higher scores on MDADI, QLQ-C30 and lower scores on PG-SGA than the control group, with significant differences (P Conclusion: Combining individualized nutrition intervention care with swallowing training improves the postoperative nutritional status, swallowing function, and QOL of patients with laryngeal cancer.展开更多
BACKGROUND Gestational diabetes mellitus(GDM)can lead to excessive pregnancy weight gain(PWG),abnormal glucolipid metabolism,and delayed lactation.Therefore,it is necessary to provide appropriate and effective interve...BACKGROUND Gestational diabetes mellitus(GDM)can lead to excessive pregnancy weight gain(PWG),abnormal glucolipid metabolism,and delayed lactation.Therefore,it is necessary to provide appropriate and effective interventions for pregnant women with GDM.AIM To clarify the effects of individualized nutrition interventions on PWG,glucolipid metabolism,and lactation in pregnant women with GDM.METHODS The study population consisted of 410 pregnant women with GDM who received treatment at the Northern Jiangsu People's Hospital of Jiangsu Provinceand Yangzhou Maternal and Child Health Hospital between December 2020 and December 2022,including 200 who received routine in-terventions[control(Con)group]and 210 who received individualized nutrition interventions[research(Res)group].Data on PWG,glucolipid metabolism[total cholesterol,(TC);triglycerides(TGs);fasting blood glucose(FPG);glycosylated hemoglobin(HbA1c)],lactation time,perinatal complications(cesarean section,premature rupture of membranes,postpartum hemorrhage,and pregnancy-induced hypertension),and neonatal adverse events(premature infants,fetal macrosomia,hypo-glycemia,and respiratory distress syndrome)were collected for comparative analysis.RESULTS The data revealed markedly lower PWG in the Res group vs the Con group,as well as markedly reduced TG,TC,FPG and HbA1c levels after the intervention that were lower than those in the Con group.In addition,obviously earlier lactation and statistically lower incidences of perinatal complications and neonatal adverse events were observed in the Res group.CONCLUSION Individualized nutrition interventions can reduce PWG in pregnant women with GDM,improve their glucolipid metabolism,and promote early lactation,which deserves clinical promotion.展开更多
目的探讨个体化营养干预对牛奶蛋白过敏(cow milk protein allergy,CMPA)患儿营养状况及生长发育的影响。方法选取2022年2月—2023年2月惠州市中心人民医院儿科收治的60例CMPA患儿作为研究对象。其中30例作为对照组给予游离氨基酸奶粉...目的探讨个体化营养干预对牛奶蛋白过敏(cow milk protein allergy,CMPA)患儿营养状况及生长发育的影响。方法选取2022年2月—2023年2月惠州市中心人民医院儿科收治的60例CMPA患儿作为研究对象。其中30例作为对照组给予游离氨基酸奶粉进行喂养,另外30例作为研究组给予个体化营养干预(包括游离氨基酸奶粉喂养、辅食回避、微量元素及维生素的合理补充)。干预6个月后,对比2组患儿生长发育指标(身高、体质量、头围)、营养指标(血红蛋白、白蛋白、转铁蛋白)、血清维生素D、钙、锌水平及干预疗效。结果干预后,研究组患儿的生长发育指标优于对照组,营养状况优于对照组,血清维生素D、钙、锌水平高于对照组(P<0.05)。研究组患儿的总有效率为100%,高于对照组的83.33%,差异有统计学意义(P<0.05)。结论对CMPA患儿给予个体化营养干预可以有效促进患儿生长发育,提升患儿营养状况,临床效果显著。展开更多
目的探讨个体化营养干预联合益气养阴方对妊娠糖尿病(GDM)病人血糖波动、血脂指标、胰岛β细胞功能的影响。方法选择2018年1月至2019年12月邢台医学高等专科学校第二附属医院收治的120例GDM病人,采用随机数字表法将病人分为两组。对照组...目的探讨个体化营养干预联合益气养阴方对妊娠糖尿病(GDM)病人血糖波动、血脂指标、胰岛β细胞功能的影响。方法选择2018年1月至2019年12月邢台医学高等专科学校第二附属医院收治的120例GDM病人,采用随机数字表法将病人分为两组。对照组(60例)采用西医常规治疗联合益气养阴方治疗,观察组(60例)在对照组基础上增加个体化营养干预。观察两组治疗前后血糖波动、血脂指标和胰岛β细胞功能差异。结果两组治疗后日内平均血糖波动幅度(MAGE)、血糖水平标准差(SDBG)、平均餐后血糖波动幅度(MPPGE)、日间血糖波动幅度(MODD)、血清总胆固醇(TC)、载脂蛋白B(ApoB)、胰岛素抵抗指标[HOMA-IR(C-P)]均下降(P<0.05),载脂蛋白A1(ApoA1)、ApoA1/ApoB比值、精氨酸刺激3 min C肽(C-P)、C-P峰值/空腹C肽(FC-P)、胰岛β细胞功能指数[HOMA-β(C-P)]升高(P<0.05)。观察组治疗后MAGE[(3.62±0.51)mmol/L比(4.25±0.69)mmol/L]、SDBG[(1.91±0.16)mmol/L比(2.12±0.21)mmol/L]、MPPGE、MODD、血清TC、ApoB、HOMA-IR(C-P)低于对照组(P<0.05),ApoA1[(1.43±0.65)g/L比(1.12±0.36)g/L]、ApoA1/ApoB比值[(1.47±0.26)比(0.97±0.20)]、精氨酸刺激3 min C-P[(6.97±1.06)μg/L比(5.09±0.76)μg/L]、C-P峰值/FC-P[(2.91±0.85)比(1.91±0.72)]、HOMA-β(C-P)[(2.16±0.77)比(1.92±0.62)]高于对照组(P<0.05)。结论个体化营养干预联合益气养阴方更有助于维持妊娠期间血糖稳定,降低血脂水平,改善胰岛β细胞储备功能,降低胰岛素抵抗。展开更多
文摘Introduction: Laryngeal carcinoma accounts for 13.9% of head and neck tumors, and squamous cell carcinoma is the main pathological type. At present, the treatment of laryngeal cancer is mainly surgical treatment or postoperative radiotherapy. The surgery is delicate, complex, time-consuming and traumatic. Postoperative patients are prone to dysphagia, leading to an increase in the incidence of malnutrition. Malnutrition can cause a series of negative effects, including weight loss, increased incidence of infection, reduced tolerance of anti-tumor treatment, and extended length of hospital stay. Therefore, how to effectively improve the nutritional status of laryngeal cancer patients through nursing intervention has become an important topic of nursing research. Objective: Investigate the effect of individualized nutrition intervention care combined with swallowing training on postoperative nutritional status in patients with laryngeal cancer. Methods: A total of 120 consecutive patients who underwent laryngeal surgery at our hospital for the first time between May 2018 and May 2021 were selected for the study and equally divided into the control group and the study group by the random number table method, with 60 patients in each group. Patients in the control group were given swallowing function training and health counseling, and the study group adopted individualized nutrition intervention care based on the control group. The nutritional status, swallowing function, and quality of life (QOL) of the patients were assessed using the Patient-generated Subjective Global Assessment (PG-SGA), MD Anderson Dysphagia Inventory (MDADI), and Quality of Life Questionnaire-Core30 (QLQ-C30) before the intervention and three months after the intervention. Results: Before the intervention, the scores of MDADI, PG-SGA, and QLQ-C30 were not significantly different between the two groups (P > 0.05), and three months after the intervention, the scores of MDADI and QLQ-C30 increased and the score of PG-SGA decreased in the study group, with significant differences (P 0.05). At three months after the intervention, patients in the study group had higher scores on MDADI, QLQ-C30 and lower scores on PG-SGA than the control group, with significant differences (P Conclusion: Combining individualized nutrition intervention care with swallowing training improves the postoperative nutritional status, swallowing function, and QOL of patients with laryngeal cancer.
基金The study was reviewed and approved by the Medical Ethics Committee of Northern Jiangsu People's Hospital of Jiangsu Province(Approval No.2023ky150).
文摘BACKGROUND Gestational diabetes mellitus(GDM)can lead to excessive pregnancy weight gain(PWG),abnormal glucolipid metabolism,and delayed lactation.Therefore,it is necessary to provide appropriate and effective interventions for pregnant women with GDM.AIM To clarify the effects of individualized nutrition interventions on PWG,glucolipid metabolism,and lactation in pregnant women with GDM.METHODS The study population consisted of 410 pregnant women with GDM who received treatment at the Northern Jiangsu People's Hospital of Jiangsu Provinceand Yangzhou Maternal and Child Health Hospital between December 2020 and December 2022,including 200 who received routine in-terventions[control(Con)group]and 210 who received individualized nutrition interventions[research(Res)group].Data on PWG,glucolipid metabolism[total cholesterol,(TC);triglycerides(TGs);fasting blood glucose(FPG);glycosylated hemoglobin(HbA1c)],lactation time,perinatal complications(cesarean section,premature rupture of membranes,postpartum hemorrhage,and pregnancy-induced hypertension),and neonatal adverse events(premature infants,fetal macrosomia,hypo-glycemia,and respiratory distress syndrome)were collected for comparative analysis.RESULTS The data revealed markedly lower PWG in the Res group vs the Con group,as well as markedly reduced TG,TC,FPG and HbA1c levels after the intervention that were lower than those in the Con group.In addition,obviously earlier lactation and statistically lower incidences of perinatal complications and neonatal adverse events were observed in the Res group.CONCLUSION Individualized nutrition interventions can reduce PWG in pregnant women with GDM,improve their glucolipid metabolism,and promote early lactation,which deserves clinical promotion.
文摘目的探讨个体化营养干预对牛奶蛋白过敏(cow milk protein allergy,CMPA)患儿营养状况及生长发育的影响。方法选取2022年2月—2023年2月惠州市中心人民医院儿科收治的60例CMPA患儿作为研究对象。其中30例作为对照组给予游离氨基酸奶粉进行喂养,另外30例作为研究组给予个体化营养干预(包括游离氨基酸奶粉喂养、辅食回避、微量元素及维生素的合理补充)。干预6个月后,对比2组患儿生长发育指标(身高、体质量、头围)、营养指标(血红蛋白、白蛋白、转铁蛋白)、血清维生素D、钙、锌水平及干预疗效。结果干预后,研究组患儿的生长发育指标优于对照组,营养状况优于对照组,血清维生素D、钙、锌水平高于对照组(P<0.05)。研究组患儿的总有效率为100%,高于对照组的83.33%,差异有统计学意义(P<0.05)。结论对CMPA患儿给予个体化营养干预可以有效促进患儿生长发育,提升患儿营养状况,临床效果显著。
文摘目的探讨个体化营养干预联合益气养阴方对妊娠糖尿病(GDM)病人血糖波动、血脂指标、胰岛β细胞功能的影响。方法选择2018年1月至2019年12月邢台医学高等专科学校第二附属医院收治的120例GDM病人,采用随机数字表法将病人分为两组。对照组(60例)采用西医常规治疗联合益气养阴方治疗,观察组(60例)在对照组基础上增加个体化营养干预。观察两组治疗前后血糖波动、血脂指标和胰岛β细胞功能差异。结果两组治疗后日内平均血糖波动幅度(MAGE)、血糖水平标准差(SDBG)、平均餐后血糖波动幅度(MPPGE)、日间血糖波动幅度(MODD)、血清总胆固醇(TC)、载脂蛋白B(ApoB)、胰岛素抵抗指标[HOMA-IR(C-P)]均下降(P<0.05),载脂蛋白A1(ApoA1)、ApoA1/ApoB比值、精氨酸刺激3 min C肽(C-P)、C-P峰值/空腹C肽(FC-P)、胰岛β细胞功能指数[HOMA-β(C-P)]升高(P<0.05)。观察组治疗后MAGE[(3.62±0.51)mmol/L比(4.25±0.69)mmol/L]、SDBG[(1.91±0.16)mmol/L比(2.12±0.21)mmol/L]、MPPGE、MODD、血清TC、ApoB、HOMA-IR(C-P)低于对照组(P<0.05),ApoA1[(1.43±0.65)g/L比(1.12±0.36)g/L]、ApoA1/ApoB比值[(1.47±0.26)比(0.97±0.20)]、精氨酸刺激3 min C-P[(6.97±1.06)μg/L比(5.09±0.76)μg/L]、C-P峰值/FC-P[(2.91±0.85)比(1.91±0.72)]、HOMA-β(C-P)[(2.16±0.77)比(1.92±0.62)]高于对照组(P<0.05)。结论个体化营养干预联合益气养阴方更有助于维持妊娠期间血糖稳定,降低血脂水平,改善胰岛β细胞储备功能,降低胰岛素抵抗。
