The elderly patients with coronary heart disease （CHD） are often accompanied with depression. This study aimed to assess the effect of St. John＇s wort extract （SWE） on depressive disorder in elderly patients with...The elderly patients with coronary heart disease （CHD） are often accompanied with depression. This study aimed to assess the effect of St. John＇s wort extract （SWE） on depressive disorder in elderly patients with unstable angina pectoris. Altogether 170 patients who met the set criteria were enrolled in this prospective study. They were randomly divided into SWE group （44 patients）, Deanxit group （44）, psychotherapy group （42）, and control group （40）. The effectiveness of SWE was evaluated by reduced percentage of Hamilton depression （HAMD） scale and reduced frequency of angina pectoris attack, which were measured before and at 12 weeks after the treatment with SWE. The reduced percentages of HAMD scale were 79.5%, 56.8% and 57.1% in the SWE, Deanxit and psychotherapy groups, respectively. Compared with the control, the three groups had significant differences in the percentages （P〈0.001）. The improvement after the treatment was more significant in the SWE group than in the Deanxit or psychotherapy group （P〈0,05）. The improvement of angina pectoris evaluated by the Canadian Cardiac Society Classification was significantly better in the treatment groups （88.7%, 65.9%, 57.1%） than in the control group, and it was marked in the SWE group （P〈0.001）. Angina pectoris attack, its frequencies, durations and electrocardiographic changes were significantly improved in the treatment groups than in the control group （F=6.05, 4.58, 5.12, P〈0.01）. They are markedly improved in the SWE group （P〈0.05）. SWE can improve depressive symptoms more significantly in elderly patients with unstable angina pectoris than Deanxit or psychotherapy, proving that SWE contributes to better treatment of angina attack as well.展开更多
A consistency condition is developed for computed tomography （CT） projection data acquired from a straight-line X-ray source trajectory. The condition states that integrals of normalized projection data along detect...A consistency condition is developed for computed tomography （CT） projection data acquired from a straight-line X-ray source trajectory. The condition states that integrals of normalized projection data along detector lines parallel to the X-ray path must be equal. The projection data is required to be untruncated only along the detector lines parallel to the X-ray path, a less restrictive requirement compared to Fourier conditions that necessitate completely untruncated data. The condition is implemented numerically on simple image functions, a discretization error bound is estimated, and detection of motion inconsistencies is demonstrated. The results show that the consistency condition may be used to quantitatively compare the quality of projection data sets obtained from different scans of the same image object.展开更多
文摘The elderly patients with coronary heart disease （CHD） are often accompanied with depression. This study aimed to assess the effect of St. John＇s wort extract （SWE） on depressive disorder in elderly patients with unstable angina pectoris. Altogether 170 patients who met the set criteria were enrolled in this prospective study. They were randomly divided into SWE group （44 patients）, Deanxit group （44）, psychotherapy group （42）, and control group （40）. The effectiveness of SWE was evaluated by reduced percentage of Hamilton depression （HAMD） scale and reduced frequency of angina pectoris attack, which were measured before and at 12 weeks after the treatment with SWE. The reduced percentages of HAMD scale were 79.5%, 56.8% and 57.1% in the SWE, Deanxit and psychotherapy groups, respectively. Compared with the control, the three groups had significant differences in the percentages （P〈0.001）. The improvement after the treatment was more significant in the SWE group than in the Deanxit or psychotherapy group （P〈0,05）. The improvement of angina pectoris evaluated by the Canadian Cardiac Society Classification was significantly better in the treatment groups （88.7%, 65.9%, 57.1%） than in the control group, and it was marked in the SWE group （P〈0.001）. Angina pectoris attack, its frequencies, durations and electrocardiographic changes were significantly improved in the treatment groups than in the control group （F=6.05, 4.58, 5.12, P〈0.01）. They are markedly improved in the SWE group （P〈0.05）. SWE can improve depressive symptoms more significantly in elderly patients with unstable angina pectoris than Deanxit or psychotherapy, proving that SWE contributes to better treatment of angina attack as well.
基金Supported in part by NIH R01 (Nos.CA120540 and EB000225)the Illinois Department of Public Health Ticket for the CureGrant. E.Y. Sidky was supported in part by a Career Development Award from NIH SPORE (No.CA125183-03)
文摘A consistency condition is developed for computed tomography （CT） projection data acquired from a straight-line X-ray source trajectory. The condition states that integrals of normalized projection data along detector lines parallel to the X-ray path must be equal. The projection data is required to be untruncated only along the detector lines parallel to the X-ray path, a less restrictive requirement compared to Fourier conditions that necessitate completely untruncated data. The condition is implemented numerically on simple image functions, a discretization error bound is estimated, and detection of motion inconsistencies is demonstrated. The results show that the consistency condition may be used to quantitatively compare the quality of projection data sets obtained from different scans of the same image object.
