Lepidopteran stem borers are the most damaging pests of maize in Sub-Saharan Africa. Despite the growing importance of maize in the forest zone of Democratic Republic of Congo, no data is available regarding stem bore...Lepidopteran stem borers are the most damaging pests of maize in Sub-Saharan Africa. Despite the growing importance of maize in the forest zone of Democratic Republic of Congo, no data is available regarding stem borer pest species present and their relative importance. It is thus important to gather information likely to guide future research in this area. This study was undertaken to catalogue stem borer pest species identity and assess their relative infestation levels on maize. Surveys were carried out in wild and cultivated habitats in Kisangani. Five species were collected on maize, i.e., Sesamia calamistis Hampson （1910）, Eldana saccharina Walker （1865）, Busseola fusca Fuller （1901）, Chilo sp. Strand （1913）, and Mussidia nigrivenella Ragonot （1888）. In the wild habitats, Poenoma serrata Hampson, B. fusca and S. calamistis were collected on Pennisetum purpureum whereas Chilo sp. was collected on Panicum maximum. Our results suggest that P. maximum might affect the population dynamics of Chilo sp. whereas P. purpureum is expected not to influence the population dynamics of other stem borers owing to its scarcity in the interior of the forest.展开更多
Decapod crustaceans are one of the dominant faunal components of most tropical streams. However, several aspects concerning their biology and ecology are poorly known, especially in intertropical Africa. The aim of th...Decapod crustaceans are one of the dominant faunal components of most tropical streams. However, several aspects concerning their biology and ecology are poorly known, especially in intertropical Africa. The aim of this study was to investigate the production of the atyid shrimps in Masanga Mabe, an equatorial lowland forest stream of Kisangani region. Samplings were undertaken biweekly from September 2000 to August 2003 with Surber net in four study sites. A total of 14,878 atyid shrimps specimens were sampled, measured for carapace length, weighted and identified. Atyid production was estimated by size frequency method according to sites （1, 2 and 3）. Atyid composition showed the existence of two species： C africana （Caridina africana） Kingsley 1882 and C togoensis （Caridina togoensis） Hilgendorf 1893. Specific production ranged from 1.35 g·DM·m^-2-year^-1 （grams dry mass per square meter per year） to 8.4 g·DM·m^-2-year^-1 for C. africana and 0.95 g·DM·m^-2-year^-1 to 4.55 g·DM·m^-2-year^-1 for C togoensis. Mean annual P/B ratios varied from 3.89 year1 to 4.37 year1 for C africana and from 3.83 year^-1 to 3.98 year^-1 for C togoensis.展开更多
Kisangani （00°31＇N 25°11＇E; Alt. 400 m） covers 1.910 km^2. The primary habitat in the region is lowland rainforest, Ornithological studies in the region began with the American Museum of Natural History ...Kisangani （00°31＇N 25°11＇E; Alt. 400 m） covers 1.910 km^2. The primary habitat in the region is lowland rainforest, Ornithological studies in the region began with the American Museum of Natural History expedition in the early 1900s. The preliminary surveys showed an interesting wealth of iconic or endemic species （e.g. Congo Peacock, Afropavo congensis and Congo Sunbird, Nectarinia congoensis）. The diversity of birds highligthed in these early surveys prompted the Faculty of Science at the University of Kisangani to begin to conduct systematic faunal studies of birds. Forest reserves, islands and disturbed environments were surveyed for birds. Capture and release and opportunistic observations were the primary survey methods. The present work provides a list of species encountered during surveys conducted at 5 sites from 1976-2014. A total of 267 species were recorded. These results provide a starting point to improve the state of knowledge about birds of Kisangani. However several natural forest sites were not surveyed： Uma, Banalia, Wania Rukula, Yangambi, Osiyo. The combination of several methods, sampling techniques and studies based on feathers, genetic material may be relevant to the assessment of avian biodiversity in this region.展开更多
In the Democratic Republic of the Congo, the sickle cell trait carriage is estimated at 25%. Routine neonatal screening is not a common practice, leading to a very late diagnosis. In this study, the screening of pregn...In the Democratic Republic of the Congo, the sickle cell trait carriage is estimated at 25%. Routine neonatal screening is not a common practice, leading to a very late diagnosis. In this study, the screening of pregnant women was assessed as well as their attitudes. This is an analytical cross-sectional study conducted in 245 pregnant women, sampled by convenience in four hospitals in Kisangani city (Democratic Republic of Congo) and screened using the sickle SCAN® test, from February 1 to July 31, 2019. The sensitivity and specificity of the latter were determined using liquid chromatography coupled with mass spectrometry as the gold standard. The attitudes of 240 pregnant women without previous screening history were assessed upon the announcement of the results. The sensitivity of screening for hemoglobin (Hb) AA and Hb AS was 96.69% and 98.39%, respectively;while the specificities were 99.43% and 96.32%, respectively. The Kappa coefficient (<i>κ</i>) was excellent. Concerning attitudes, Hb SS pregnant women and 55.17% of AS pregnant women worried when the results relating to their hemoglobin status were announced. The sickle SCAN® test was found reliable for sickle cell disease screening in Kisangani. The announcement of the results, mainly positive, raises worry among pregnant woman. Therefore, we recommend the involvement of a clinician psychologist for pre-screening counselling and for results announcement, as well as early newborns and unmarried teenage girls screening.展开更多
The Makiso municipality is located in an urban area influenced by a very high rate of land occupation by houses. This land use has an impact on the quality of the groundwater exploited by wells and springs. This groun...The Makiso municipality is located in an urban area influenced by a very high rate of land occupation by houses. This land use has an impact on the quality of the groundwater exploited by wells and springs. This groundwater helps to make up for the deficit caused by the lack of a water distribution network. It is also threatened by pollution from human activities. In order to protect the groundwater in Makiso municipality from pollution, the study of the intrinsic vulnerability assessment in the aquifers was carried out by applying the DRASTIC method and the Geographic Information System (GIS). The results obtained using this method were grouped into two degrees of vulnerability (medium and high), with variations in DRASTIC indices of [141 - 145] for the medium degree and [146 - 175] for the high degree. The high vulnerability class is the most dominant, with a percentage of 96.5% of the study area. The medium vulnerability class, which represents 3.5% of the area of the Makiso municipality, is mainly located in the western (medical plateau district), central (Lualaba district) and southern (commercial district) sectors in the form of isolated pockets. A comparison of the nitrate distribution map with the final vulnerability map shows that the areas defined as highly vulnerable by the DRASTIC method and the areas with high nitrate concentrations (above 0.11 mg/l) are in agreement. On the other hand, there are other areas with low nitrate concentrations (below 0.05 mg/l) which correspond to the high vulnerability indices.展开更多
The classic picture of a hydatiform mole is made of recurrent metrorrhagia, exaggeration of sympathetic signs, increase of uterine volume compared to gestational age and marked elevation of serum β-hCG. The occurrenc...The classic picture of a hydatiform mole is made of recurrent metrorrhagia, exaggeration of sympathetic signs, increase of uterine volume compared to gestational age and marked elevation of serum β-hCG. The occurrence of preeclampsia is less common and its mechanism is less well known. In this case, the authors report an atypical presentation of the complete hydatiform mole alarmed by chronic hypertension with preeclampsia added to a pregnant woman of 39 years. The management involved stopping the pregnancy and normalization of the blood pressure figures was spectacular after uterine aspiration.展开更多
Background: Amputations and disarticulation of the limbs are becoming a public health problem. Goal: To describe the epidemiological and etiological aspects of limb amputation in Kisangani. Methods: A retrospective st...Background: Amputations and disarticulation of the limbs are becoming a public health problem. Goal: To describe the epidemiological and etiological aspects of limb amputation in Kisangani. Methods: A retrospective study of three health facilities in the city of Kisangani: Kisangani Clinical University, General Hospital Makiso-Kisangani Reference and Kabondo Reference General Hospital from 1st January 2005 to 31st December 2014 counted 62 cases of amputation. Results: The prevalence of 14.69% of all interventions of limbs. The age group of 57 - 75 years is the most concerned and the male/female sex ratio is 2.9/1. The unemployed are most affected 51.6%. The lower limb is concerned in 88.7%, including 30.6% in the lower leg and the right side is reached in 56.5% of cases. Diabetic gangrene (30.1%) is criminalized followed by traumatism (27.4%). The mortality rate is 17.8%. Conclusion: The amputation of limbs is a situation encountered in Kisangani. The adult male is most affected. Diabetic gangrene and open fractures are the most encountered causes. Mortality is high. The early management of diabetics and open fractures is a mandatory.展开更多
Introduction: Gestational malaria is a major public health problem because it is a threat to pregnant women and their children. As Kisangani is a stable malaria transmission area and there is a paucity of data on the ...Introduction: Gestational malaria is a major public health problem because it is a threat to pregnant women and their children. As Kisangani is a stable malaria transmission area and there is a paucity of data on the status of gestational malaria in our settings, we have found it appropriate to determine the prevalence of gestational malaria and its determinants in Kisangani City. Methods: We conducted a cross-sectional analytical study in Kisangani from January 1 to September 30, 2017. Our population study consisted of 1248 parturients recruited at delivery. We made the thick drop in peripheral blood from parturients at the admission and at the level of placental impressions after delivery. Results: The average age of the respondents was 25.3971 ± 6.2452 years;the overall prevalence of gestational malaria was 27.56% including 12.66% peripheral parasitaemia, 12.34% placental parasitaemia and 2.56% parasitaemia level and placental and peripheral blood impressions. Youngest age ≤ 18 years [OR (95% CI) = 2.44 (1.75 - 3.41), p 0.001], primiparity [OR (95% CI) = 2.94 (2.00 - 4.32), p 0.001] and positive HIV serology [OR (95% CI) = 3.01 (1.23 - 7.43), p = 0.008] increased the risk of gestational malaria;the use of mosquito net impregnated with insecticide [OR (95% CI) = 0.29 (0.14 - 0.61), p 0.001] reduced this risk. Conclusion: The prevalence of gestational malaria is 27.56% in Kisangani. The youngest age ≤ 18 years, the primiparity and positive HIV serology of pregnant women were the most associated risk factors.展开更多
Background: The consequences of malaria during pregnancy are different regarding local conditions of malaria transmission. In stable malaria areas, the main complications are maternal anaemia and fetal growth restrict...Background: The consequences of malaria during pregnancy are different regarding local conditions of malaria transmission. In stable malaria areas, the main complications are maternal anaemia and fetal growth restriction. This study aims to determine if pregnancy-associated malaria is associated with the risk of the above-mentioned complications and to determine if IPTp-sp reduces them in Kisangani. Methods: It is a cross-sectional analytical study conducted in parturients, in 6 medical facilities of Kisangani, from January 1st to September 30th, 2017. At delivery we measured their hemoglobin, we performed the thick blood smear of their peripheral blood and placental apposition;and we weighed their newborns at birth. Results: Risk of anaemia at delivery increased with malaria access during pregnancy (p = 0.0056;OR: 1.4221, 95% CI: 1.0851 - 1.8638) and peripheral parasitaemia at delivery (p = 0.0000;OR: 6.3855, 95% CI: 4.5552 - 8.9512). LBW increased with peripheral parasitaemia at delivery (p = 0.0000;OR: 3.5299, 95% CI: 2.4424 - 5.1015) and placental parasitaemia (p = 0.0000;OR: 18.3247, 95% CI: 12.5141 - 26.8332). IPTp-sp did not have effect on maternal hemoglobin at delivery (p = 0.1546;OR: 0.7553, IC à 95%: 0.4414 - 1.2923) and the birth weight (p = 0.1225;OR: 0.6638, IC à 95%: 0.3375 - 1.3056). Conclusion: In Kisangani, pregnancy-associated malaria is associated with maternal anaemia at delivery and LBW. IPTp-sp does not reduce the risk of these complications. Therefore, studies evaluating IPTp alternatives are required in malaria endemic areas.展开更多
Introduction: Trace element deficiency is a major nutritional problem worldwide, affecting more than two billion people, or around a quarter of the world’s population. This situation is even more acute in developing ...Introduction: Trace element deficiency is a major nutritional problem worldwide, affecting more than two billion people, or around a quarter of the world’s population. This situation is even more acute in developing countries than in developed countries. In sub-Saharan Africa, research and recent data on trace elements (micronutrients) are scarce. The aim of this study was to determine the serum status of calcium (Ca+), copper (Cu), magnesium (Mg), selenium (Se) and zinc (Zn) in women of childbearing age in Kisangani. Methods: We have conducted a descriptive cross-sectional study in Kisangani, Democratic Republic of the Congo. Our sample consists of 596 women of childbearing age in apparent good health. The data collection has been prospective. Concentrations of trace elements in serum were analysed using an inductively coupled plasma mass spectrophotometer (ICP-MS Agilent 7700X). Results: The mean and median concentrations were: Calcium: 2.35 mmol/l and 2.31 mmol/l, Copper: 13.55 and 13.49 µmol/l, Magnesium: 0.85 and 0.81 mmol/l, Selenium: 0.99 and 0.76 µmol/l, and Zinc: 13.85 and 13.79 µmol/l. Respondents aged 20 - 34 had mean serum concentrations of 2.4 mmol/l for calcium, 13.7 µmol/l for copper, 0.9 mmol/l for magnesium, 1.1 µmol/l for selenium and 14.0 µmol/l for zinc. Conclusion: The trace element status of women of childbearing age in Kisangani was lower than that observed by other researchers, which suggests the need for a general nutritional intervention in our environment.展开更多
<strong>Introduction:</strong> Induction of labor has become an increasingly utilized obstetric intervention in developed countries. It contributes to reduce the maternal and perinatal morbidity and mortal...<strong>Introduction:</strong> Induction of labor has become an increasingly utilized obstetric intervention in developed countries. It contributes to reduce the maternal and perinatal morbidity and mortality. Dinoprostone derivatives are often used under cardiotocography. In poor countries, health structures have neither fetal monitoring, nor means of preserving Dinoprostone derivatives. Misoprostol therefore constitutes an alternative. This study seeks to establish the efficacy and safety of oral Misoprostol and to assess maternal and perinatal prognosis in an area with limited resource. <strong>Methods: </strong>This is a multi-center clinical trial, conducted in 3 hospitals centers in Kisangani, Tshopo Province/Democratic Republic of Congo from December 1, 2020 to May 31, 2021. Our sample was constituted with 68 pregnant women with term pregnancy. Fifty micrograms of Misoprostol was administered orally. The data were collected prospectively, their encoding was carried out on an Excel sheet 2013 and their analysis carried out using the EPI INFO software. <strong>Results:</strong> The average age of the pregnant women was 23.17 ± 5.76 years. The average parity was 1.02 ± 1.2. The average body mass index (BMI) was 24.98 ± 2.55 Kg/m<sup>2</sup>. 66 (97.1%) patients had received a maximum of 3 doses of Misoprostol. Out of the 16 parturients who received 3 doses or more, 11 (68.8%) had a BMI ≥ 25. The average duration of labor was 16.03 ± 7.99 hours. 66 (97.1%) pregnant women had delivered vaginally. 57 (83.8%) patients delivered within 24 hours. Out of the 11 patients who delivered after 24 hours, 7 (63.6%) had a BMI ≥ 25. The induction failure rate was 2.9% (2 patients). 2 (2.9%) fetuses had presented pathological modification of fetal heart rate (FHR). 2 (2.9%) patients had undergone cesarean section. <strong>Conclusion:</strong> Labor induction with oral Misoprostol is effective and associated with low maternal and perinatal morbidity. A BMI ≥ 25 kg/m<sup>2</sup> increases the number of doses to be given and the duration of labor.展开更多
Background: Infants with latent tuberculosis are often subject to high morbidity, nutritional deficiency and mortality. Early treatment can prevent the onset of TB by reducing morbidity and improving nutritional statu...Background: Infants with latent tuberculosis are often subject to high morbidity, nutritional deficiency and mortality. Early treatment can prevent the onset of TB by reducing morbidity and improving nutritional status. This paper assessed whether preventive chemotherapy for TB can improve health and nutritional status of infants diagnosed with latent TB in Kisangani City. Method: Children diagnosed TB+ by tuberculin skin test and other clinical examinations were treated with Rifampicin, Isoniazid, Pyrazinamide and Ethambutol. Clinical symptoms and nutritional status were determined before to start treatment and at the 5th month of treatment. Results: Out of 161 infants treated, 73 (45.3%) were 37°C) was 62.7% before treatment and 17.4% at the 5th month of treatment;the difference was statistically significant (p Conclusion: Treatment of infants diagnosed of latent TB prevents TB disease and improves nutritional status, but not in all cases. Control of fever and weight gain can be an indicator of good outcome in poor health care settings.展开更多
文摘Lepidopteran stem borers are the most damaging pests of maize in Sub-Saharan Africa. Despite the growing importance of maize in the forest zone of Democratic Republic of Congo, no data is available regarding stem borer pest species present and their relative importance. It is thus important to gather information likely to guide future research in this area. This study was undertaken to catalogue stem borer pest species identity and assess their relative infestation levels on maize. Surveys were carried out in wild and cultivated habitats in Kisangani. Five species were collected on maize, i.e., Sesamia calamistis Hampson （1910）, Eldana saccharina Walker （1865）, Busseola fusca Fuller （1901）, Chilo sp. Strand （1913）, and Mussidia nigrivenella Ragonot （1888）. In the wild habitats, Poenoma serrata Hampson, B. fusca and S. calamistis were collected on Pennisetum purpureum whereas Chilo sp. was collected on Panicum maximum. Our results suggest that P. maximum might affect the population dynamics of Chilo sp. whereas P. purpureum is expected not to influence the population dynamics of other stem borers owing to its scarcity in the interior of the forest.
文摘Decapod crustaceans are one of the dominant faunal components of most tropical streams. However, several aspects concerning their biology and ecology are poorly known, especially in intertropical Africa. The aim of this study was to investigate the production of the atyid shrimps in Masanga Mabe, an equatorial lowland forest stream of Kisangani region. Samplings were undertaken biweekly from September 2000 to August 2003 with Surber net in four study sites. A total of 14,878 atyid shrimps specimens were sampled, measured for carapace length, weighted and identified. Atyid production was estimated by size frequency method according to sites （1, 2 and 3）. Atyid composition showed the existence of two species： C africana （Caridina africana） Kingsley 1882 and C togoensis （Caridina togoensis） Hilgendorf 1893. Specific production ranged from 1.35 g·DM·m^-2-year^-1 （grams dry mass per square meter per year） to 8.4 g·DM·m^-2-year^-1 for C. africana and 0.95 g·DM·m^-2-year^-1 to 4.55 g·DM·m^-2-year^-1 for C togoensis. Mean annual P/B ratios varied from 3.89 year1 to 4.37 year1 for C africana and from 3.83 year^-1 to 3.98 year^-1 for C togoensis.
文摘Kisangani （00°31＇N 25°11＇E; Alt. 400 m） covers 1.910 km^2. The primary habitat in the region is lowland rainforest, Ornithological studies in the region began with the American Museum of Natural History expedition in the early 1900s. The preliminary surveys showed an interesting wealth of iconic or endemic species （e.g. Congo Peacock, Afropavo congensis and Congo Sunbird, Nectarinia congoensis）. The diversity of birds highligthed in these early surveys prompted the Faculty of Science at the University of Kisangani to begin to conduct systematic faunal studies of birds. Forest reserves, islands and disturbed environments were surveyed for birds. Capture and release and opportunistic observations were the primary survey methods. The present work provides a list of species encountered during surveys conducted at 5 sites from 1976-2014. A total of 267 species were recorded. These results provide a starting point to improve the state of knowledge about birds of Kisangani. However several natural forest sites were not surveyed： Uma, Banalia, Wania Rukula, Yangambi, Osiyo. The combination of several methods, sampling techniques and studies based on feathers, genetic material may be relevant to the assessment of avian biodiversity in this region.
文摘In the Democratic Republic of the Congo, the sickle cell trait carriage is estimated at 25%. Routine neonatal screening is not a common practice, leading to a very late diagnosis. In this study, the screening of pregnant women was assessed as well as their attitudes. This is an analytical cross-sectional study conducted in 245 pregnant women, sampled by convenience in four hospitals in Kisangani city (Democratic Republic of Congo) and screened using the sickle SCAN® test, from February 1 to July 31, 2019. The sensitivity and specificity of the latter were determined using liquid chromatography coupled with mass spectrometry as the gold standard. The attitudes of 240 pregnant women without previous screening history were assessed upon the announcement of the results. The sensitivity of screening for hemoglobin (Hb) AA and Hb AS was 96.69% and 98.39%, respectively;while the specificities were 99.43% and 96.32%, respectively. The Kappa coefficient (<i>κ</i>) was excellent. Concerning attitudes, Hb SS pregnant women and 55.17% of AS pregnant women worried when the results relating to their hemoglobin status were announced. The sickle SCAN® test was found reliable for sickle cell disease screening in Kisangani. The announcement of the results, mainly positive, raises worry among pregnant woman. Therefore, we recommend the involvement of a clinician psychologist for pre-screening counselling and for results announcement, as well as early newborns and unmarried teenage girls screening.
文摘The Makiso municipality is located in an urban area influenced by a very high rate of land occupation by houses. This land use has an impact on the quality of the groundwater exploited by wells and springs. This groundwater helps to make up for the deficit caused by the lack of a water distribution network. It is also threatened by pollution from human activities. In order to protect the groundwater in Makiso municipality from pollution, the study of the intrinsic vulnerability assessment in the aquifers was carried out by applying the DRASTIC method and the Geographic Information System (GIS). The results obtained using this method were grouped into two degrees of vulnerability (medium and high), with variations in DRASTIC indices of [141 - 145] for the medium degree and [146 - 175] for the high degree. The high vulnerability class is the most dominant, with a percentage of 96.5% of the study area. The medium vulnerability class, which represents 3.5% of the area of the Makiso municipality, is mainly located in the western (medical plateau district), central (Lualaba district) and southern (commercial district) sectors in the form of isolated pockets. A comparison of the nitrate distribution map with the final vulnerability map shows that the areas defined as highly vulnerable by the DRASTIC method and the areas with high nitrate concentrations (above 0.11 mg/l) are in agreement. On the other hand, there are other areas with low nitrate concentrations (below 0.05 mg/l) which correspond to the high vulnerability indices.
文摘The classic picture of a hydatiform mole is made of recurrent metrorrhagia, exaggeration of sympathetic signs, increase of uterine volume compared to gestational age and marked elevation of serum β-hCG. The occurrence of preeclampsia is less common and its mechanism is less well known. In this case, the authors report an atypical presentation of the complete hydatiform mole alarmed by chronic hypertension with preeclampsia added to a pregnant woman of 39 years. The management involved stopping the pregnancy and normalization of the blood pressure figures was spectacular after uterine aspiration.
文摘Background: Amputations and disarticulation of the limbs are becoming a public health problem. Goal: To describe the epidemiological and etiological aspects of limb amputation in Kisangani. Methods: A retrospective study of three health facilities in the city of Kisangani: Kisangani Clinical University, General Hospital Makiso-Kisangani Reference and Kabondo Reference General Hospital from 1st January 2005 to 31st December 2014 counted 62 cases of amputation. Results: The prevalence of 14.69% of all interventions of limbs. The age group of 57 - 75 years is the most concerned and the male/female sex ratio is 2.9/1. The unemployed are most affected 51.6%. The lower limb is concerned in 88.7%, including 30.6% in the lower leg and the right side is reached in 56.5% of cases. Diabetic gangrene (30.1%) is criminalized followed by traumatism (27.4%). The mortality rate is 17.8%. Conclusion: The amputation of limbs is a situation encountered in Kisangani. The adult male is most affected. Diabetic gangrene and open fractures are the most encountered causes. Mortality is high. The early management of diabetics and open fractures is a mandatory.
文摘Introduction: Gestational malaria is a major public health problem because it is a threat to pregnant women and their children. As Kisangani is a stable malaria transmission area and there is a paucity of data on the status of gestational malaria in our settings, we have found it appropriate to determine the prevalence of gestational malaria and its determinants in Kisangani City. Methods: We conducted a cross-sectional analytical study in Kisangani from January 1 to September 30, 2017. Our population study consisted of 1248 parturients recruited at delivery. We made the thick drop in peripheral blood from parturients at the admission and at the level of placental impressions after delivery. Results: The average age of the respondents was 25.3971 ± 6.2452 years;the overall prevalence of gestational malaria was 27.56% including 12.66% peripheral parasitaemia, 12.34% placental parasitaemia and 2.56% parasitaemia level and placental and peripheral blood impressions. Youngest age ≤ 18 years [OR (95% CI) = 2.44 (1.75 - 3.41), p 0.001], primiparity [OR (95% CI) = 2.94 (2.00 - 4.32), p 0.001] and positive HIV serology [OR (95% CI) = 3.01 (1.23 - 7.43), p = 0.008] increased the risk of gestational malaria;the use of mosquito net impregnated with insecticide [OR (95% CI) = 0.29 (0.14 - 0.61), p 0.001] reduced this risk. Conclusion: The prevalence of gestational malaria is 27.56% in Kisangani. The youngest age ≤ 18 years, the primiparity and positive HIV serology of pregnant women were the most associated risk factors.
基金Faculty of Medicine and Pharmacy of University of Kisangani
文摘Background: The consequences of malaria during pregnancy are different regarding local conditions of malaria transmission. In stable malaria areas, the main complications are maternal anaemia and fetal growth restriction. This study aims to determine if pregnancy-associated malaria is associated with the risk of the above-mentioned complications and to determine if IPTp-sp reduces them in Kisangani. Methods: It is a cross-sectional analytical study conducted in parturients, in 6 medical facilities of Kisangani, from January 1st to September 30th, 2017. At delivery we measured their hemoglobin, we performed the thick blood smear of their peripheral blood and placental apposition;and we weighed their newborns at birth. Results: Risk of anaemia at delivery increased with malaria access during pregnancy (p = 0.0056;OR: 1.4221, 95% CI: 1.0851 - 1.8638) and peripheral parasitaemia at delivery (p = 0.0000;OR: 6.3855, 95% CI: 4.5552 - 8.9512). LBW increased with peripheral parasitaemia at delivery (p = 0.0000;OR: 3.5299, 95% CI: 2.4424 - 5.1015) and placental parasitaemia (p = 0.0000;OR: 18.3247, 95% CI: 12.5141 - 26.8332). IPTp-sp did not have effect on maternal hemoglobin at delivery (p = 0.1546;OR: 0.7553, IC à 95%: 0.4414 - 1.2923) and the birth weight (p = 0.1225;OR: 0.6638, IC à 95%: 0.3375 - 1.3056). Conclusion: In Kisangani, pregnancy-associated malaria is associated with maternal anaemia at delivery and LBW. IPTp-sp does not reduce the risk of these complications. Therefore, studies evaluating IPTp alternatives are required in malaria endemic areas.
文摘Introduction: Trace element deficiency is a major nutritional problem worldwide, affecting more than two billion people, or around a quarter of the world’s population. This situation is even more acute in developing countries than in developed countries. In sub-Saharan Africa, research and recent data on trace elements (micronutrients) are scarce. The aim of this study was to determine the serum status of calcium (Ca+), copper (Cu), magnesium (Mg), selenium (Se) and zinc (Zn) in women of childbearing age in Kisangani. Methods: We have conducted a descriptive cross-sectional study in Kisangani, Democratic Republic of the Congo. Our sample consists of 596 women of childbearing age in apparent good health. The data collection has been prospective. Concentrations of trace elements in serum were analysed using an inductively coupled plasma mass spectrophotometer (ICP-MS Agilent 7700X). Results: The mean and median concentrations were: Calcium: 2.35 mmol/l and 2.31 mmol/l, Copper: 13.55 and 13.49 µmol/l, Magnesium: 0.85 and 0.81 mmol/l, Selenium: 0.99 and 0.76 µmol/l, and Zinc: 13.85 and 13.79 µmol/l. Respondents aged 20 - 34 had mean serum concentrations of 2.4 mmol/l for calcium, 13.7 µmol/l for copper, 0.9 mmol/l for magnesium, 1.1 µmol/l for selenium and 14.0 µmol/l for zinc. Conclusion: The trace element status of women of childbearing age in Kisangani was lower than that observed by other researchers, which suggests the need for a general nutritional intervention in our environment.
文摘<strong>Introduction:</strong> Induction of labor has become an increasingly utilized obstetric intervention in developed countries. It contributes to reduce the maternal and perinatal morbidity and mortality. Dinoprostone derivatives are often used under cardiotocography. In poor countries, health structures have neither fetal monitoring, nor means of preserving Dinoprostone derivatives. Misoprostol therefore constitutes an alternative. This study seeks to establish the efficacy and safety of oral Misoprostol and to assess maternal and perinatal prognosis in an area with limited resource. <strong>Methods: </strong>This is a multi-center clinical trial, conducted in 3 hospitals centers in Kisangani, Tshopo Province/Democratic Republic of Congo from December 1, 2020 to May 31, 2021. Our sample was constituted with 68 pregnant women with term pregnancy. Fifty micrograms of Misoprostol was administered orally. The data were collected prospectively, their encoding was carried out on an Excel sheet 2013 and their analysis carried out using the EPI INFO software. <strong>Results:</strong> The average age of the pregnant women was 23.17 ± 5.76 years. The average parity was 1.02 ± 1.2. The average body mass index (BMI) was 24.98 ± 2.55 Kg/m<sup>2</sup>. 66 (97.1%) patients had received a maximum of 3 doses of Misoprostol. Out of the 16 parturients who received 3 doses or more, 11 (68.8%) had a BMI ≥ 25. The average duration of labor was 16.03 ± 7.99 hours. 66 (97.1%) pregnant women had delivered vaginally. 57 (83.8%) patients delivered within 24 hours. Out of the 11 patients who delivered after 24 hours, 7 (63.6%) had a BMI ≥ 25. The induction failure rate was 2.9% (2 patients). 2 (2.9%) fetuses had presented pathological modification of fetal heart rate (FHR). 2 (2.9%) patients had undergone cesarean section. <strong>Conclusion:</strong> Labor induction with oral Misoprostol is effective and associated with low maternal and perinatal morbidity. A BMI ≥ 25 kg/m<sup>2</sup> increases the number of doses to be given and the duration of labor.
文摘Background: Infants with latent tuberculosis are often subject to high morbidity, nutritional deficiency and mortality. Early treatment can prevent the onset of TB by reducing morbidity and improving nutritional status. This paper assessed whether preventive chemotherapy for TB can improve health and nutritional status of infants diagnosed with latent TB in Kisangani City. Method: Children diagnosed TB+ by tuberculin skin test and other clinical examinations were treated with Rifampicin, Isoniazid, Pyrazinamide and Ethambutol. Clinical symptoms and nutritional status were determined before to start treatment and at the 5th month of treatment. Results: Out of 161 infants treated, 73 (45.3%) were 37°C) was 62.7% before treatment and 17.4% at the 5th month of treatment;the difference was statistically significant (p Conclusion: Treatment of infants diagnosed of latent TB prevents TB disease and improves nutritional status, but not in all cases. Control of fever and weight gain can be an indicator of good outcome in poor health care settings.
