Based on four phases of TM images acquired in 1990, 1995, 2000 and 2005, this paper took Kitakyushu in Japan as a case study to analyze spatial change of land use landscape and corresponding effects on environmental i...Based on four phases of TM images acquired in 1990, 1995, 2000 and 2005, this paper took Kitakyushu in Japan as a case study to analyze spatial change of land use landscape and corresponding effects on environmental issues guided by landscape ecology theory in virtue of combining technology of Remote Sensing with GIS. Firstly, land use types were divided into 6 classes （farmland, mountain, forestland, water body, urban land and unused land） according to national classification standard of land use, comprehensible ability of TM image and purpose of this study. Secondly, following the theory of landscape ecology analysis, 11 typical landscape indices were abstracted to evaluate the environmental effects and spatial feature changes of land use. Research results indicated that land use has grown more and more diversified and unbalanced, human activities have disturbed the landscape more seriously. Finally, transfer matrix of Markov was applied to forecast change process of land use in the future different periods, and then potential land use changes were also simulated from 2010 to 2050. Results showed that conversion tendency for all types of land use in Kitakyushu into urban construction land were enhanced. The study was anticipated to help local authorities better understand and address a complex land use system, and develop improved land use management strategies that could better balance urban expansion and ecological conservation.展开更多
With increasing of serious environment problems and the coming of the aging society, new traffic systems should be urgently rebuilt. It is necessary to evaluate the traffic service level by utilizing new technique and...With increasing of serious environment problems and the coming of the aging society, new traffic systems should be urgently rebuilt. It is necessary to evaluate the traffic service level by utilizing new technique and tool. This paper takes Kitakyushu city as case study to carry out an evaluation of urban traffic system. The concept of accessibility and mobility is used to evaluate the present condition of existing public traffic system based on GIS technology, and then establishment of new route is discussed according to the evaluation results. Additionally, this paper established GIS database and illustrated the relationship between the public traffic and population density. The regions without enough existing traffic were identified. Moreover, the essential terms and considerations were put forward to simulate a new route of public traffic line.展开更多
AIM To assess cancer-testis antigens(CTAs) expression in gastric cancer patients and examined their associations with clinicopathological factors.METHODS Eighty-three gastric cancer patients were evaluated in this stu...AIM To assess cancer-testis antigens(CTAs) expression in gastric cancer patients and examined their associations with clinicopathological factors.METHODS Eighty-three gastric cancer patients were evaluated in this study. Gastric cancer specimens were evaluated for the gene expression of CTAs, Kitakyushu lung cancer antigen-1(KK-LC-1), melanoma antigen(MAGE)-A1, MAGE-A3 and New York esophageal cancer-1(NYESO-1), by reverse transcription PCR. Clinicopathological background information, such as gender, age, tumor size, macroscopic type, tumor histology, depth of invasion, lymph node metastasis, lymphatic invasion, venous invasion, and pathological stage, was obtained. Statistical comparisons between the expression of each CTA and each clinicopathological background were performed using the χ2 test. RESULTS The expression rates of KK-LC-1, MAGE-A1, MAGE-A3, and NY-ESO-1 were 79.5%, 32.5%, 39.8%, and 15.7%, respectively. In early stage gastric cancer specimens, the expression of KK-LC-1 was 79.4%, which is comparable to the 79.6% observed in advanced stage specimens. The expression of KK-LC-1 was not significantly associated with clinicopathological factors, while there were considerable differences in the expression rates of MAGE-A1 and MAGE-A3 with vs without lymphatic invasion(MAGE-A1, 39.3% vs 13.6%, P = 0.034; MAGE-A3, 47.5% vs 18.2%, P = 0.022) and/or vascular invasion(MAGE-A1, 41.5% vs 16.7%, P = 0.028; MAGE-A3, 49.1% vs 23.3%, P = 0.035) and, particularly, MAGE-A3, in patients with early vs advanced stage(36.5% vs 49.0%, P = 0.044), respectively. Patients expressing MAGE-A3 and NYESO-1 were older than those not expressing MAGE-A3 and NY-ESO-1(MAGE-A3, 73.7 ± 7.1 vs 67.4 ± 12.3, P = 0.009; NY-ESO-1, 75.5 ± 7.2 vs 68.8 ± 11.2, P = 0.042). CONCLUSION The KK-LC-1 expression rate was high even in patients with stage I cancer, suggesting that KK-LC-1 is a useful biomarker for early diagnosis of gastric cancer.展开更多
随着全球环境形势的日益严峻,自然环境保护和生态文明建设越来越重要。大学校园在环境保护和可持续发展方面的主导地位证明建设绿色大学势在必行。首先阐述了绿色大学的产生和涵义,然后从绿色教育和绿色校园两方面出发,以北九州学术研...随着全球环境形势的日益严峻,自然环境保护和生态文明建设越来越重要。大学校园在环境保护和可持续发展方面的主导地位证明建设绿色大学势在必行。首先阐述了绿色大学的产生和涵义,然后从绿色教育和绿色校园两方面出发,以北九州学术研究都市(Kitakyushu Science and Research Park)为案例说明绿色大学建设的基本内容,最后总结案例高校独特的产学研连携的教育模式和节能技术,为中国绿色大学的建设提供经验。展开更多
基金Sasakawa Scientific Foundation of Japan, No.20-238 National Basic Research Program of China （973 Program）, No.2006CB403200+1 种基金 National Natural Science Foundation of China, No.40261002 No.40561006
文摘Based on four phases of TM images acquired in 1990, 1995, 2000 and 2005, this paper took Kitakyushu in Japan as a case study to analyze spatial change of land use landscape and corresponding effects on environmental issues guided by landscape ecology theory in virtue of combining technology of Remote Sensing with GIS. Firstly, land use types were divided into 6 classes （farmland, mountain, forestland, water body, urban land and unused land） according to national classification standard of land use, comprehensible ability of TM image and purpose of this study. Secondly, following the theory of landscape ecology analysis, 11 typical landscape indices were abstracted to evaluate the environmental effects and spatial feature changes of land use. Research results indicated that land use has grown more and more diversified and unbalanced, human activities have disturbed the landscape more seriously. Finally, transfer matrix of Markov was applied to forecast change process of land use in the future different periods, and then potential land use changes were also simulated from 2010 to 2050. Results showed that conversion tendency for all types of land use in Kitakyushu into urban construction land were enhanced. The study was anticipated to help local authorities better understand and address a complex land use system, and develop improved land use management strategies that could better balance urban expansion and ecological conservation.
文摘With increasing of serious environment problems and the coming of the aging society, new traffic systems should be urgently rebuilt. It is necessary to evaluate the traffic service level by utilizing new technique and tool. This paper takes Kitakyushu city as case study to carry out an evaluation of urban traffic system. The concept of accessibility and mobility is used to evaluate the present condition of existing public traffic system based on GIS technology, and then establishment of new route is discussed according to the evaluation results. Additionally, this paper established GIS database and illustrated the relationship between the public traffic and population density. The regions without enough existing traffic were identified. Moreover, the essential terms and considerations were put forward to simulate a new route of public traffic line.
基金Supported by Grant-in-Aid for research by Kitasato University Medical Center,No.H25-0006 and the JSPS,KAKENHI,No.26670609 to Futawatari Nthe JSPS,KAKENHI,No.21700510 and No.17K16578,Takeda Science Foundation and Kitasato University Research Grant for Young Researchers to Fukuyama T
文摘AIM To assess cancer-testis antigens(CTAs) expression in gastric cancer patients and examined their associations with clinicopathological factors.METHODS Eighty-three gastric cancer patients were evaluated in this study. Gastric cancer specimens were evaluated for the gene expression of CTAs, Kitakyushu lung cancer antigen-1(KK-LC-1), melanoma antigen(MAGE)-A1, MAGE-A3 and New York esophageal cancer-1(NYESO-1), by reverse transcription PCR. Clinicopathological background information, such as gender, age, tumor size, macroscopic type, tumor histology, depth of invasion, lymph node metastasis, lymphatic invasion, venous invasion, and pathological stage, was obtained. Statistical comparisons between the expression of each CTA and each clinicopathological background were performed using the χ2 test. RESULTS The expression rates of KK-LC-1, MAGE-A1, MAGE-A3, and NY-ESO-1 were 79.5%, 32.5%, 39.8%, and 15.7%, respectively. In early stage gastric cancer specimens, the expression of KK-LC-1 was 79.4%, which is comparable to the 79.6% observed in advanced stage specimens. The expression of KK-LC-1 was not significantly associated with clinicopathological factors, while there were considerable differences in the expression rates of MAGE-A1 and MAGE-A3 with vs without lymphatic invasion(MAGE-A1, 39.3% vs 13.6%, P = 0.034; MAGE-A3, 47.5% vs 18.2%, P = 0.022) and/or vascular invasion(MAGE-A1, 41.5% vs 16.7%, P = 0.028; MAGE-A3, 49.1% vs 23.3%, P = 0.035) and, particularly, MAGE-A3, in patients with early vs advanced stage(36.5% vs 49.0%, P = 0.044), respectively. Patients expressing MAGE-A3 and NYESO-1 were older than those not expressing MAGE-A3 and NY-ESO-1(MAGE-A3, 73.7 ± 7.1 vs 67.4 ± 12.3, P = 0.009; NY-ESO-1, 75.5 ± 7.2 vs 68.8 ± 11.2, P = 0.042). CONCLUSION The KK-LC-1 expression rate was high even in patients with stage I cancer, suggesting that KK-LC-1 is a useful biomarker for early diagnosis of gastric cancer.
文摘随着全球环境形势的日益严峻,自然环境保护和生态文明建设越来越重要。大学校园在环境保护和可持续发展方面的主导地位证明建设绿色大学势在必行。首先阐述了绿色大学的产生和涵义,然后从绿色教育和绿色校园两方面出发,以北九州学术研究都市(Kitakyushu Science and Research Park)为案例说明绿色大学建设的基本内容,最后总结案例高校独特的产学研连携的教育模式和节能技术,为中国绿色大学的建设提供经验。
