Skilled individual agents are firm basis of a strong soccer team. The skills available to Everest 2002 (agents) include kicking, dribbling, forwarding, ball interception and tackling. These intermediate sub goals are ...Skilled individual agents are firm basis of a strong soccer team. The skills available to Everest 2002 (agents) include kicking, dribbling, forwarding, ball interception and tackling. These intermediate sub goals are implemented by a combination of local optimization which hopes to determine the optimal primitive action from a local perspective and adversarial consideration which takes into account opponents and limitations imposed by simulation environment. Everest 2002 RoboCup simulation teams, building on 11 skilled agents and an on-line coach, won the 2nd place in RoboCup 2002 simulation league.展开更多
Infectious diseases,mostly caused by bacteria and viruses but also a result of fungal and parasitic infection,have been one of the most important public health concerns throughout human history.The first step in comba...Infectious diseases,mostly caused by bacteria and viruses but also a result of fungal and parasitic infection,have been one of the most important public health concerns throughout human history.The first step in combating these pathogens is to get a timely and accurate diagnosis at an affordable cost.Many kinds of diagnostics have been developed,such as pathogen culture,biochemical tests and serological tests,to help detect and fight against the causative agents of diseases.However,these diagnostic tests are generally unsatisfactory because they are not particularly sensitive and specific and are unable to deliver speedy results.Nucleic acid-based diagnostics,detecting pathogens through the identification of their genomic sequences,have shown promise to overcome the above limitations and become more widely adopted in clinical tests.Here we review some of the most popular nucleic acid-based diagnostics and focus on their adaptability and applicability to routine clinical usage.We also compare and contrast the characteristics of different types of nucleic acid-based diagnostics.展开更多
Changes in terrestrial near-surface wind speed(NSWS)are indicative of the concentrated net effect of climate change and anthropogenic activities.Investigating change mechanisms of NSWS not only furthers the understand...Changes in terrestrial near-surface wind speed(NSWS)are indicative of the concentrated net effect of climate change and anthropogenic activities.Investigating change mechanisms of NSWS not only furthers the understanding of how the atmosphere changes and improves the climate analysis and projection,but also aids the evaluation and application of wind energy resources.Recent advances in studies of the changes and associated mechanisms of the NSWS over China are reviewed in this paper.Some new results have been achieved in understanding the behaviors of the NSWS changes.The NSWS over China has experienced a decrease in the past 40 years and a recovery in the recent decade,exhibiting large regional and seasonal differences.Understanding of the mechanisms of the NSWS changes has been improved in several aspects;for example,it is found that the reduced NSWS over China is due to the weakening of the pressure-gradient force(PGF)attributed to variations in large-scale ocean–atmosphere circulations(LOACs)as well as the increase of surface roughness due to the land use and cover change(LUCC).The main methods used to analyze the NSWS changes and corresponding mechanisms are also elucidated and discussed.However,studies are still lacking on the mechanisms for multi-timescale(seasonal,interannual,decadal,multidecadal)variations in the NSWS over China,and it remains unknown about the contributions of different forcing factors to the NSWS changes.Finally,key scientific issues regarding our understanding of the NSWS changes are proposed for future investigation.展开更多
文摘Skilled individual agents are firm basis of a strong soccer team. The skills available to Everest 2002 (agents) include kicking, dribbling, forwarding, ball interception and tackling. These intermediate sub goals are implemented by a combination of local optimization which hopes to determine the optimal primitive action from a local perspective and adversarial consideration which takes into account opponents and limitations imposed by simulation environment. Everest 2002 RoboCup simulation teams, building on 11 skilled agents and an on-line coach, won the 2nd place in RoboCup 2002 simulation league.
基金supported by grants from the National Key Technology R&D Program(No.2008BAK41B01-5)the National Science and Technology Major Project—Development New Genetically Modified Organism(No.2009ZX08012-006B).
文摘Infectious diseases,mostly caused by bacteria and viruses but also a result of fungal and parasitic infection,have been one of the most important public health concerns throughout human history.The first step in combating these pathogens is to get a timely and accurate diagnosis at an affordable cost.Many kinds of diagnostics have been developed,such as pathogen culture,biochemical tests and serological tests,to help detect and fight against the causative agents of diseases.However,these diagnostic tests are generally unsatisfactory because they are not particularly sensitive and specific and are unable to deliver speedy results.Nucleic acid-based diagnostics,detecting pathogens through the identification of their genomic sequences,have shown promise to overcome the above limitations and become more widely adopted in clinical tests.Here we review some of the most popular nucleic acid-based diagnostics and focus on their adaptability and applicability to routine clinical usage.We also compare and contrast the characteristics of different types of nucleic acid-based diagnostics.
基金Supported by the National Key Research and Development Program of China(2018YFA0606004 and 2016YFA0600403)National Natural Science Foundation of China(42005023,41875178,41775087,and 41675149)China Postdoctoral Science Foundation(2019M660761)。
文摘Changes in terrestrial near-surface wind speed(NSWS)are indicative of the concentrated net effect of climate change and anthropogenic activities.Investigating change mechanisms of NSWS not only furthers the understanding of how the atmosphere changes and improves the climate analysis and projection,but also aids the evaluation and application of wind energy resources.Recent advances in studies of the changes and associated mechanisms of the NSWS over China are reviewed in this paper.Some new results have been achieved in understanding the behaviors of the NSWS changes.The NSWS over China has experienced a decrease in the past 40 years and a recovery in the recent decade,exhibiting large regional and seasonal differences.Understanding of the mechanisms of the NSWS changes has been improved in several aspects;for example,it is found that the reduced NSWS over China is due to the weakening of the pressure-gradient force(PGF)attributed to variations in large-scale ocean–atmosphere circulations(LOACs)as well as the increase of surface roughness due to the land use and cover change(LUCC).The main methods used to analyze the NSWS changes and corresponding mechanisms are also elucidated and discussed.However,studies are still lacking on the mechanisms for multi-timescale(seasonal,interannual,decadal,multidecadal)variations in the NSWS over China,and it remains unknown about the contributions of different forcing factors to the NSWS changes.Finally,key scientific issues regarding our understanding of the NSWS changes are proposed for future investigation.
