A Kerr-lens mode-locked Ti：sapphire laser operating in a non-soliton regime is demonstrated. Dispersive wave generation is observed as a result of third order dispersion in the vicinity of zero dispersion. The charac...A Kerr-lens mode-locked Ti：sapphire laser operating in a non-soliton regime is demonstrated. Dispersive wave generation is observed as a result of third order dispersion in the vicinity of zero dispersion. The characteristics of the Ti：sapphire l^ser operating in a positive dispersion regime are presented, where the oscillator directly generates pulses with duration continuously tunable from 0.37 ps to 2.11 ps, and 36 fs pulses are achieved atter extracavity compression. The oscillation is numerically simulated with an extended nonlinear Schr6dinger equation, and the simulation results are in good agreement with the experimental results.展开更多
AIM： To investigate the difference in kappa angle between sitting and supine positions during laser-assisted in situ keratomileusis（LASIK）.·METHODS： A retrospective study was performed on395 eyes from 215 pat...AIM： To investigate the difference in kappa angle between sitting and supine positions during laser-assisted in situ keratomileusis（LASIK）.·METHODS： A retrospective study was performed on395 eyes from 215 patients with myopia that received LASIK. Low, moderate, and high myopia groups were assigned according to diopters. The horizontal and vertical components of kappa angle in sitting position were measured before the operation, and in supine position during the operation. The data from the two positions were compared and the relationship between kappa angle and diopters were analyzed.· RESULTS： Two hundred and twenty-three eyes（56.5%） in sitting position and 343 eyes（86.8%） in supine position had positive kappa angles. There were no significant differences in horizontal and vertical components of kappa angle in the sitting position or horizontal components of kappa angle in the supine position between the three groups（P 〉0.05）. A significant difference in the vertical components of kappa angle in the supine position was seen in the three groups（P 〈0.01）. Differences in both horizontal and vertical components of kappa angles were significant between the sitting and supine positions. Positive correlations in both horizontal and vertical components of kappa angles（P 〈0.05） were found and vertical components of kappa angle in sitting and supine positions were negatively correlated with the degree of myopia（sitting position： r =-0.109; supine position： r =-0.172; P 〈0.05）.·CONCLUSION： There is a correlation in horizontal and vertical components of kappa angle in sitting and supine positions. Positive correlations in both horizontal and vertical components of kappa angle in sitting and supine positions till the end of the results. This result still needs further observation. Clinicians should take into account different postures when excimer laser surgery needs to be performed.展开更多
The propagation of an intense laser pulse in an under-dense plasma induces a plasma wake that is suitable for the acceleration of electrons to relativistic energies. For an ultra-intense laser pulse which has a longit...The propagation of an intense laser pulse in an under-dense plasma induces a plasma wake that is suitable for the acceleration of electrons to relativistic energies. For an ultra-intense laser pulse which has a longitudinal size shorter than the plasma wavelength, λp, instead of a periodic plasma wave, a cavity free from cold plasma electrons, called a bubble, is formed behind the laser pulse. An intense charge separation electric field inside the moving bubble can capture the electrons at the base of the bubble and accelerate them with a narrow energy spread. In the nonlinear bubble regime, due to localized depletion at the front of the pulse during its propagation through the plasma, the phase shift between carrier waves and pulse envelope plays an important role in plasma response. The carrier–envelope phase（CEP） breaks down the symmetric transverse ponderomotive force of the laser pulse that makes the bubble structure unstable. Our studies using a series of two-dimensional（2D） particle-in-cell（PIC） simulations show that the frequency-chirped laser pulses are more effective in controlling the pulse depletion rate and consequently the effect of the CEP in the bubble regime. The results indicate that the utilization of a positively chirped laser pulse leads to an increase in rate of erosion of the leading edge of the pulse that rapidly results in the formation of a steep intensity gradient at the front of the pulse. A more unstable bubble structure, the self-injections in different positions, and high dark current are the results of using a positively chirped laser pulse. For a negatively chirped laser pulse, the pulse depletion process is compensated during the propagation of the pulse in plasma in such a way that results in a more stable bubble shape and therefore, a localized electron bunch is produced during the acceleration process. As a result, by the proper choice of chirping, one can tune the number of self-injected electrons, the size of accelerated bunch and its energy spectrum to the values required for practical applications.展开更多
Silver nanoparticles in the range of 10-40 nm were synthesized chemically and by laser ablation, em- ployed for in vitro antibacterial action against human pathogenic bacterium. Their formation was evidenced by UV-vis...Silver nanoparticles in the range of 10-40 nm were synthesized chemically and by laser ablation, em- ployed for in vitro antibacterial action against human pathogenic bacterium. Their formation was evidenced by UV-visible spectrophotometer; particle size confirmed by atomic force microscopy, crystal structure determined by X-ray diffraction and chemical composition investigated by Fourier transform infrared spec- troscopy. The calculated MIC （minimum inhibitory concentration） of chemically synthesized nanoparticles with 30-40 nm in size are 2.8 μg/mL 4.37 μg/mL 13.5μg/mL and 2.81 p.g/mL for E. coil, S. aureus, B. subtillis and Salmonella, respectively. Whereas laser ablated nanoparticles exhibit MIC of 2.10 μg/mL 2.36 μg/ mL and 2.68 μg/mL for E. coli, S. aureus and Salmonella, respectively.展开更多
基金Project supported by the National Basic Research Program of China (Grant No. 2006CB806002)the National High Technology Research and Development Program of China (Grant No. 2007AA03Z447)+3 种基金National Natural Science Foundation of China (Grant Nos. 60678012 and 60838004)the Foundation for Key Program of Ministry of Education, China (Grant No. 108032)FANEDD(Grant No. 2007B34)NCET (Grant No. NCET-07-0597)
文摘A Kerr-lens mode-locked Ti：sapphire laser operating in a non-soliton regime is demonstrated. Dispersive wave generation is observed as a result of third order dispersion in the vicinity of zero dispersion. The characteristics of the Ti：sapphire l^ser operating in a positive dispersion regime are presented, where the oscillator directly generates pulses with duration continuously tunable from 0.37 ps to 2.11 ps, and 36 fs pulses are achieved atter extracavity compression. The oscillation is numerically simulated with an extended nonlinear Schr6dinger equation, and the simulation results are in good agreement with the experimental results.
文摘AIM： To investigate the difference in kappa angle between sitting and supine positions during laser-assisted in situ keratomileusis（LASIK）.·METHODS： A retrospective study was performed on395 eyes from 215 patients with myopia that received LASIK. Low, moderate, and high myopia groups were assigned according to diopters. The horizontal and vertical components of kappa angle in sitting position were measured before the operation, and in supine position during the operation. The data from the two positions were compared and the relationship between kappa angle and diopters were analyzed.· RESULTS： Two hundred and twenty-three eyes（56.5%） in sitting position and 343 eyes（86.8%） in supine position had positive kappa angles. There were no significant differences in horizontal and vertical components of kappa angle in the sitting position or horizontal components of kappa angle in the supine position between the three groups（P 〉0.05）. A significant difference in the vertical components of kappa angle in the supine position was seen in the three groups（P 〈0.01）. Differences in both horizontal and vertical components of kappa angles were significant between the sitting and supine positions. Positive correlations in both horizontal and vertical components of kappa angles（P 〈0.05） were found and vertical components of kappa angle in sitting and supine positions were negatively correlated with the degree of myopia（sitting position： r =-0.109; supine position： r =-0.172; P 〈0.05）.·CONCLUSION： There is a correlation in horizontal and vertical components of kappa angle in sitting and supine positions. Positive correlations in both horizontal and vertical components of kappa angle in sitting and supine positions till the end of the results. This result still needs further observation. Clinicians should take into account different postures when excimer laser surgery needs to be performed.
文摘The propagation of an intense laser pulse in an under-dense plasma induces a plasma wake that is suitable for the acceleration of electrons to relativistic energies. For an ultra-intense laser pulse which has a longitudinal size shorter than the plasma wavelength, λp, instead of a periodic plasma wave, a cavity free from cold plasma electrons, called a bubble, is formed behind the laser pulse. An intense charge separation electric field inside the moving bubble can capture the electrons at the base of the bubble and accelerate them with a narrow energy spread. In the nonlinear bubble regime, due to localized depletion at the front of the pulse during its propagation through the plasma, the phase shift between carrier waves and pulse envelope plays an important role in plasma response. The carrier–envelope phase（CEP） breaks down the symmetric transverse ponderomotive force of the laser pulse that makes the bubble structure unstable. Our studies using a series of two-dimensional（2D） particle-in-cell（PIC） simulations show that the frequency-chirped laser pulses are more effective in controlling the pulse depletion rate and consequently the effect of the CEP in the bubble regime. The results indicate that the utilization of a positively chirped laser pulse leads to an increase in rate of erosion of the leading edge of the pulse that rapidly results in the formation of a steep intensity gradient at the front of the pulse. A more unstable bubble structure, the self-injections in different positions, and high dark current are the results of using a positively chirped laser pulse. For a negatively chirped laser pulse, the pulse depletion process is compensated during the propagation of the pulse in plasma in such a way that results in a more stable bubble shape and therefore, a localized electron bunch is produced during the acceleration process. As a result, by the proper choice of chirping, one can tune the number of self-injected electrons, the size of accelerated bunch and its energy spectrum to the values required for practical applications.
文摘Silver nanoparticles in the range of 10-40 nm were synthesized chemically and by laser ablation, em- ployed for in vitro antibacterial action against human pathogenic bacterium. Their formation was evidenced by UV-visible spectrophotometer; particle size confirmed by atomic force microscopy, crystal structure determined by X-ray diffraction and chemical composition investigated by Fourier transform infrared spec- troscopy. The calculated MIC （minimum inhibitory concentration） of chemically synthesized nanoparticles with 30-40 nm in size are 2.8 μg/mL 4.37 μg/mL 13.5μg/mL and 2.81 p.g/mL for E. coil, S. aureus, B. subtillis and Salmonella, respectively. Whereas laser ablated nanoparticles exhibit MIC of 2.10 μg/mL 2.36 μg/ mL and 2.68 μg/mL for E. coli, S. aureus and Salmonella, respectively.
