Optimization algorithms play a pivotal role in enhancing the performance and efficiency of systems across various scientific and engineering disciplines.To enhance the performance and alleviate the limitations of the ...Optimization algorithms play a pivotal role in enhancing the performance and efficiency of systems across various scientific and engineering disciplines.To enhance the performance and alleviate the limitations of the Northern Goshawk Optimization(NGO)algorithm,particularly its tendency towards premature convergence and entrapment in local optima during function optimization processes,this study introduces an advanced Improved Northern Goshawk Optimization(INGO)algorithm.This algorithm incorporates a multifaceted enhancement strategy to boost operational efficiency.Initially,a tent chaotic map is employed in the initialization phase to generate a diverse initial population,providing high-quality feasible solutions.Subsequently,after the first phase of the NGO’s iterative process,a whale fall strategy is introduced to prevent premature convergence into local optima.This is followed by the integration of T-distributionmutation strategies and the State Transition Algorithm(STA)after the second phase of the NGO,achieving a balanced synergy between the algorithm’s exploitation and exploration.This research evaluates the performance of INGO using 23 benchmark functions alongside the IEEE CEC 2017 benchmark functions,accompanied by a statistical analysis of the results.The experimental outcomes demonstrate INGO’s superior achievements in function optimization tasks.Furthermore,its applicability in solving engineering design problems was verified through simulations on Unmanned Aerial Vehicle(UAV)trajectory planning issues,establishing INGO’s capability in addressing complex optimization challenges.展开更多
In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs （superconducting quantum-interference devices） in cavity via Raman transition. The scheme only requires a quantize...In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs （superconducting quantum-interference devices） in cavity via Raman transition. The scheme only requires a quantized cavity field and classical microwave pulses. In this scheme, no transfer of quantum information between the SQUIDs and the cavity is required, the cavity field is only virtually excited and thus the cavity decay is suppressed.展开更多
A new arrival and departure flight classification method based on the transitive closure algorithm （TCA） is proposed. Firstly, the fuzzy set theory and the transitive closure algorithm are introduced. Then four diff...A new arrival and departure flight classification method based on the transitive closure algorithm （TCA） is proposed. Firstly, the fuzzy set theory and the transitive closure algorithm are introduced. Then four different factors are selected to establish the flight classification model and a method is given to calculate the delay cost for each class. Finally, the proposed method is implemented in the sequencing problems of flights in a terminal area, and results are compared with that of the traditional classification method（TCM）. Results show that the new classification model is effective in reducing the expenses of flight delays, thus optimizing the sequences of arrival and departure flights, and improving the efficiency of air traffic control.展开更多
Due to the fact that headway is a key factor to be considered in bus scheduling, this paper proposes a bi-level programming model for optimizing bus headway in public transit lines. In this model, with the interests o...Due to the fact that headway is a key factor to be considered in bus scheduling, this paper proposes a bi-level programming model for optimizing bus headway in public transit lines. In this model, with the interests of bus companies and passengers in mind, the upper-level model＇s objective is to minimize the total cost, which is affected by frequency settings, both in time and economy in the transit system. The lower-level model is a transit assignment model used to describe the assignment of passengers＇ trips to the network based on the optimal bus headway. In order to solve the proposed model, a hybrid genetic algorithm, namely the genetic algorithm and the simulated annealing algorithm （GA-SA）, is designed. Finally, the model and the algorithm are tested against the transit data, by taking some of the bus lines of Changzhou city as an example. Results indicate that the proposed model allows supply and demand to be linked, which is reasonable, and the solving algorithm is effective.展开更多
Objective:Circulating tumor cells(CTCs)play a critical role in cancer metastasis,but their prevalence and significance remain unclear.This study attempted to track the epithelial-mesenchymal transition(EMT)status of C...Objective:Circulating tumor cells(CTCs)play a critical role in cancer metastasis,but their prevalence and significance remain unclear.This study attempted to track the epithelial-mesenchymal transition(EMT)status of CTCs in breast cancer patients and investigate their clinical relevance.Methods:In this study,the established negFACS-IF:E/M platform was applied to isolate rare CTCs and characterize their EMT status in breast cancer.A total of 89 breast cancer patients were recruited,including stage 0–III(n=60)and late stage(n=29)cases.Results:Using the negFACS-IF:E/M platform,it was found that in human epidermal growth factor receptor 2(HER2)+patients,mesenchymal CTCs usually exhibited a high percentage of HER2+cells.Stage IV breast cancer patients had considerably more CTCs than stage 0–III patients.Among stage 0–III breast cancers,the HER2 subtype included a significantly higher percentage of mesenchymal and biphenotypic(epithelial and mesenchymal)CTCs than the luminal A or B subtypes.Among stage IV patients,CTCs were predominantly epithelial in cases with local recurrence and were more mesenchymal in cases with distant metastasis.By applying a support vector machine(SVM)algorithm,the EMT status of CTCs could distinguish between breast cancer cases with metastasis/local recurrence and those without recurrence.Conclusions:The negFACS-IF:E/M platform provides a flexible and generally acceptable method for the highly sensitive and specific detection of CTCs and their EMT traits in breast cancer.This study demonstrated that the EMT status of CTCs had high clinical relevance in breast cancer,especially in predicting the distant metastasis or local recurrence of breast cancer.展开更多
Based on the framework of method of successive averages(MSA), a modified stochastic user-equilibrium assignment algorithm was proposed, which can be used to calculate the passenger flow distribution of urban rail tran...Based on the framework of method of successive averages(MSA), a modified stochastic user-equilibrium assignment algorithm was proposed, which can be used to calculate the passenger flow distribution of urban rail transit(URT) under network operation. In order to describe the congestion's impact to passengers' route choices, a generalized cost function with in-vehicle congestion was set up. Building on the k-th shortest path algorithm, a method for generating choice set with time constraint was embedded, considering the characteristics of network operation. A simple but efficient route choice model, which was derived from travel surveys for URT passengers in China, was introduced to perform the stochastic network loading at each iteration in the algorithm. Initial tests on the URT network in Shanghai City show that the methodology, with rational calculation time, promises to compute more precisely the passenger flow distribution of URT under network operation, compared with those practical algorithms used in today's China.展开更多
Public transit planning is a user-oriented problem, respectful of financial issues and involves different stakeholders such as the general public, the transportation provider and the local government. One of the main ...Public transit planning is a user-oriented problem, respectful of financial issues and involves different stakeholders such as the general public, the transportation provider and the local government. One of the main components of public transit planning is the transit network design (TND) problem. This research is an attempt to perform transit network design and analysis in the city of Sanandaj, Iran using the capabilities of GIS and Honeybee algorithm. Objectives of this study are formulating a multi-objective model of the TND problem, developing a GIS-based procedure for solving the TND problem and examination of the solutions using artificial metaheuristic methods such as honeybee algorithm. The transit network design approach in this research, aims to reduce the walking distance, the total travel distance and the total number of stops needed for a suitable transit service in Sanandaj, Iran. One of the contributions of this research is developing a transit network design with utilizing a spectrum of GIS software modelling functionalities and using the abilities of the artificial intelligence in modelling and assessment of the transit network.展开更多
蚁群算法拥有良好的全局性、自组织性、鲁棒性,但传统蚁群算法存在许多不足之处。为此,针对算法在路径规划问题中的缺陷,在传统蚁群算法的状态转移公式中,引入目标点距离因素和引导素,加快算法收敛性和改善局部最优缺陷。在带时间窗的...蚁群算法拥有良好的全局性、自组织性、鲁棒性,但传统蚁群算法存在许多不足之处。为此,针对算法在路径规划问题中的缺陷,在传统蚁群算法的状态转移公式中,引入目标点距离因素和引导素,加快算法收敛性和改善局部最优缺陷。在带时间窗的车辆路径问题(vehicle routing problem with time windows,VRPTW)上,融合蚁群算法和遗传算法,并将顾客时间窗宽度以及机器人等待时间加入蚁群算法状态转移公式中,以及将蚁群算法的解作为遗传算法的初始种群,提高遗传算法的初始解质量,然后进行编码,设置违反时间窗约束和载重量的惩罚函数和适应度函数,在传统遗传算法的交叉、变异操作后加入了破坏-修复基因的操作来优化每一代新解的质量,在Solomon Benchmark算例上进行仿真,对比算法改进前后的最优解,验证算法可行性。最后在餐厅送餐问题中把带有障碍物的仿真环境路径规划问题和VRPTW问题结合,使用改进后的算法解决餐厅环境下送餐机器人对顾客服务配送问题。展开更多
基金supported by theKey Research and Development Project of Hubei Province(No.2023BAB094)the Key Project of Science and Technology Research Program of Hubei Educational Committee(No.D20211402)the Open Foundation of HubeiKey Laboratory for High-Efficiency Utilization of Solar Energy and Operation Control of Energy Storage System(No.HBSEES202309).
文摘Optimization algorithms play a pivotal role in enhancing the performance and efficiency of systems across various scientific and engineering disciplines.To enhance the performance and alleviate the limitations of the Northern Goshawk Optimization(NGO)algorithm,particularly its tendency towards premature convergence and entrapment in local optima during function optimization processes,this study introduces an advanced Improved Northern Goshawk Optimization(INGO)algorithm.This algorithm incorporates a multifaceted enhancement strategy to boost operational efficiency.Initially,a tent chaotic map is employed in the initialization phase to generate a diverse initial population,providing high-quality feasible solutions.Subsequently,after the first phase of the NGO’s iterative process,a whale fall strategy is introduced to prevent premature convergence into local optima.This is followed by the integration of T-distributionmutation strategies and the State Transition Algorithm(STA)after the second phase of the NGO,achieving a balanced synergy between the algorithm’s exploitation and exploration.This research evaluates the performance of INGO using 23 benchmark functions alongside the IEEE CEC 2017 benchmark functions,accompanied by a statistical analysis of the results.The experimental outcomes demonstrate INGO’s superior achievements in function optimization tasks.Furthermore,its applicability in solving engineering design problems was verified through simulations on Unmanned Aerial Vehicle(UAV)trajectory planning issues,establishing INGO’s capability in addressing complex optimization challenges.
基金supported in part by Scientific Research Program of Hubei Provincial Department of Education under Grant No.D200634001Natural Science Foundation of Jiangxi Province under Grant No. 0612006
文摘In this paper, a theoretical scheme is proposed to implement the Deutsch-Jozsa algorithm with SQUIDs （superconducting quantum-interference devices） in cavity via Raman transition. The scheme only requires a quantized cavity field and classical microwave pulses. In this scheme, no transfer of quantum information between the SQUIDs and the cavity is required, the cavity field is only virtually excited and thus the cavity decay is suppressed.
文摘A new arrival and departure flight classification method based on the transitive closure algorithm （TCA） is proposed. Firstly, the fuzzy set theory and the transitive closure algorithm are introduced. Then four different factors are selected to establish the flight classification model and a method is given to calculate the delay cost for each class. Finally, the proposed method is implemented in the sequencing problems of flights in a terminal area, and results are compared with that of the traditional classification method（TCM）. Results show that the new classification model is effective in reducing the expenses of flight delays, thus optimizing the sequences of arrival and departure flights, and improving the efficiency of air traffic control.
基金The National Natural Science Foundation of China(No.50978057)the National Key Technology R& D Program of China duringthe 11th Five-Year Plan Period (No.2006BAJ18B03)+1 种基金the Scientific Research Foundation of Graduate School of Southeast University ( No.YBJJ1013)the Program for Postgraduates Research Innovation in University of Jiangsu Province(No.CX09B 060Z)
文摘Due to the fact that headway is a key factor to be considered in bus scheduling, this paper proposes a bi-level programming model for optimizing bus headway in public transit lines. In this model, with the interests of bus companies and passengers in mind, the upper-level model＇s objective is to minimize the total cost, which is affected by frequency settings, both in time and economy in the transit system. The lower-level model is a transit assignment model used to describe the assignment of passengers＇ trips to the network based on the optimal bus headway. In order to solve the proposed model, a hybrid genetic algorithm, namely the genetic algorithm and the simulated annealing algorithm （GA-SA）, is designed. Finally, the model and the algorithm are tested against the transit data, by taking some of the bus lines of Changzhou city as an example. Results indicate that the proposed model allows supply and demand to be linked, which is reasonable, and the solving algorithm is effective.
基金mostly supported through the funding provided by the National Natural Science Foundation of China(Grant No.81702866)the Key Program of the Natural Science Foundation of Zhejiang Province(Grant No.LZ16H160002)+2 种基金the Zhejiang Provincial Program for the Cultivation of HighLevel Innovative Health Talentsthe Foundation of the Education Department of Zhejiang Province(Grant No.Y201636451)partially supported through funding provided by the National Natural Science Foundation of China(Grant No.81472666)。
文摘Objective:Circulating tumor cells(CTCs)play a critical role in cancer metastasis,but their prevalence and significance remain unclear.This study attempted to track the epithelial-mesenchymal transition(EMT)status of CTCs in breast cancer patients and investigate their clinical relevance.Methods:In this study,the established negFACS-IF:E/M platform was applied to isolate rare CTCs and characterize their EMT status in breast cancer.A total of 89 breast cancer patients were recruited,including stage 0–III(n=60)and late stage(n=29)cases.Results:Using the negFACS-IF:E/M platform,it was found that in human epidermal growth factor receptor 2(HER2)+patients,mesenchymal CTCs usually exhibited a high percentage of HER2+cells.Stage IV breast cancer patients had considerably more CTCs than stage 0–III patients.Among stage 0–III breast cancers,the HER2 subtype included a significantly higher percentage of mesenchymal and biphenotypic(epithelial and mesenchymal)CTCs than the luminal A or B subtypes.Among stage IV patients,CTCs were predominantly epithelial in cases with local recurrence and were more mesenchymal in cases with distant metastasis.By applying a support vector machine(SVM)algorithm,the EMT status of CTCs could distinguish between breast cancer cases with metastasis/local recurrence and those without recurrence.Conclusions:The negFACS-IF:E/M platform provides a flexible and generally acceptable method for the highly sensitive and specific detection of CTCs and their EMT traits in breast cancer.This study demonstrated that the EMT status of CTCs had high clinical relevance in breast cancer,especially in predicting the distant metastasis or local recurrence of breast cancer.
基金Project(2007AA11Z236) supported by the National High Technology Research and Development Program of ChinaProject(2012M5209O1) supported by China Postdoctoral Science Foundation
文摘Based on the framework of method of successive averages(MSA), a modified stochastic user-equilibrium assignment algorithm was proposed, which can be used to calculate the passenger flow distribution of urban rail transit(URT) under network operation. In order to describe the congestion's impact to passengers' route choices, a generalized cost function with in-vehicle congestion was set up. Building on the k-th shortest path algorithm, a method for generating choice set with time constraint was embedded, considering the characteristics of network operation. A simple but efficient route choice model, which was derived from travel surveys for URT passengers in China, was introduced to perform the stochastic network loading at each iteration in the algorithm. Initial tests on the URT network in Shanghai City show that the methodology, with rational calculation time, promises to compute more precisely the passenger flow distribution of URT under network operation, compared with those practical algorithms used in today's China.
文摘Public transit planning is a user-oriented problem, respectful of financial issues and involves different stakeholders such as the general public, the transportation provider and the local government. One of the main components of public transit planning is the transit network design (TND) problem. This research is an attempt to perform transit network design and analysis in the city of Sanandaj, Iran using the capabilities of GIS and Honeybee algorithm. Objectives of this study are formulating a multi-objective model of the TND problem, developing a GIS-based procedure for solving the TND problem and examination of the solutions using artificial metaheuristic methods such as honeybee algorithm. The transit network design approach in this research, aims to reduce the walking distance, the total travel distance and the total number of stops needed for a suitable transit service in Sanandaj, Iran. One of the contributions of this research is developing a transit network design with utilizing a spectrum of GIS software modelling functionalities and using the abilities of the artificial intelligence in modelling and assessment of the transit network.
文摘蚁群算法拥有良好的全局性、自组织性、鲁棒性,但传统蚁群算法存在许多不足之处。为此,针对算法在路径规划问题中的缺陷,在传统蚁群算法的状态转移公式中,引入目标点距离因素和引导素,加快算法收敛性和改善局部最优缺陷。在带时间窗的车辆路径问题(vehicle routing problem with time windows,VRPTW)上,融合蚁群算法和遗传算法,并将顾客时间窗宽度以及机器人等待时间加入蚁群算法状态转移公式中,以及将蚁群算法的解作为遗传算法的初始种群,提高遗传算法的初始解质量,然后进行编码,设置违反时间窗约束和载重量的惩罚函数和适应度函数,在传统遗传算法的交叉、变异操作后加入了破坏-修复基因的操作来优化每一代新解的质量,在Solomon Benchmark算例上进行仿真,对比算法改进前后的最优解,验证算法可行性。最后在餐厅送餐问题中把带有障碍物的仿真环境路径规划问题和VRPTW问题结合,使用改进后的算法解决餐厅环境下送餐机器人对顾客服务配送问题。
