Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa....Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa. Compared to pure components, both binary and ternary mixtures showed lower heat transfer coefficients.This deterioration was more pronounced as heat flux was increased. Experimental data were compared with some empirical and semi-empirical correlations available in literature. For binary mixture, the accuracy of the correlations varied considerably with mixtures and the heat flux. Experimental data for HFC-32/134a/125 were also compared with available correlated equation obtained by Thome. For ternary mixture, the boiling range of binary mixture composed by the pure fluids with the lowest and the medium boiling points, and their concentration difference had important effects on boiling heat transfer coefficients.展开更多
A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blo...A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blood cells（FNRBCs） in the peripheral blood of a gravida were rapidly and effectively enriched and separated by the mo- dified multi-core magnetic composite particles in an external magnetic field. The obtained FNRBCs were used for the identification of the fetal sex by means of fluorescence in situ hybridization（FISH） technique. The results demonstrate that the multi-core magnetic composite particles meet the requirements for the enrichment and speration of FNRBCs with a low concentration and the accuracy of detetion for the diagnosis of fetal sex reached to 95%. Moreover, the obtained FNRBCs were applied to the non-invasive diagnosis of Down syndrome and chromosome 3p21 was de- tected. The above facts indicate that the novel multi-core magnetic composite particles-based method is simple, relia- ble and cost-effective and has opened up vast vistas for the potential application in clinic non-invasive prenatal diag- nosis.展开更多
This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizonta...This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizontal circular plates of brass, copper and aluminum. The heat transfer coefficient was evaluated by measuring wall superheat and effective heat flux removed by boiling. The experiments were carried out in the heat flux range of 8 to 200 kW/m2. The obtained results have shown significant effect of surface material, with copper providing the highest heat transfer coefficient among the samples, and aluminum the least. There was negligible difference at low heat fluxes, but copper showed 23% better performance at high heat fluxes than aluminum and 18% better than brass.展开更多
To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells wer...To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells were isolated from maternal blood by using discontinuous density gradient centrifugation. Some of the isolated cells were made smear and counted under the microscope; others were used for predicting fetal sex by PCR amplification of Y chromosome specific DYZ1 gene. The major cells in the upper separation interface were lymphocytes and monocytes, with occasionally seen nucleated red blood cells (NRBC); while those in the middle separation interface were neutrocytes, with NRBC scattering. The ratio of NRBC/nucleated cells was 1. 98±0. 28× 10-5. There was no significant difference between the first and second trimester (P>0. 05). The amount of isolated fetal cells was sufficient for prenatal genetic diagnosis. Male pregnancy was correctly predicted in 10 out of 13 cases. It is concluded that the method of discontinuous density gradient centrifugation was of considerable importance in the development of non-invasive prenatal genetic diagnosis.展开更多
Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleat...Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleate boiling with additives has been investigated, and the results indicate that one of the important reasons is that the nucleation sites have been increased.展开更多
In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral bloo...In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral blood of 88 pregnant women by density gradient centrifugation and fluorescence activated cell sorter (FACS) respectively. Nested polymerase chain reaction was used to detect normal male SRY gene from blood plasma DNA of 65 pregnant women. The results revealed that fetal NRBCs were found in 14 of 27 maternal samples by density gradient centrifugation. The number of cells was from 1 to 10. Using FACS, CD71 + cells were identified among all 61 samples. The frequency was (0.35±0.25)×10 -2; The detectable rate of the SRY gene of blood plasma DNA from 46 women carrying male fetuses was 65.22 % (30/46). Non-detectable rate for 19 women carrying female fetuses was 94.74 % (18/19). It was concluded that the methods of sorting fetal NRBCs and DNA have already made great progress. The methods for fetal NRBCs and plasma DNA from maternal peripheral blood to diagnose genetic diseases seem to be the best methods of noninvasive prenatal diagnosis.展开更多
The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for nonin...The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for noninvasive prenatal diagnosis. Single fetal nucleated erythroblasts were isolated from the peripheral blood samples from 51 pregnant women by micromanipulation techniques after density gradient centrifugation. Nested polymerase chain reaction method was used to amplify the SRY gene. It was found that the concordance rate of amplification results with real fetal sex was 82.61 %. The sensitivity and specificity were 80 % and 87.50 % respectively. It was suggested that it is feasible and promising in non invasive prenatal diagnosis to detect fetal nucleated erythroblasts at a single cell level by using micromanipulation techniques.展开更多
With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equatio...With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equation in this paper. In our discussion, no parameter is introduced externally, and our results are in good agreement with the experimental results.展开更多
Nucleate pool boiling process is widely used in heat exchangers because of its excellent heat transfer performance.With the gradual increase of applications,more and more equipments work in a non-static state,but ther...Nucleate pool boiling process is widely used in heat exchangers because of its excellent heat transfer performance.With the gradual increase of applications,more and more equipments work in a non-static state,but there is little research under rolling conditions.Therefore,it is necessary to investigate the influence of rolling motion on the nucleate pool boiling process.In this study,a numerical investigation of the nucleate pool boiling process under static and rolling conditions is performed based on the volume-of-fluid(VOF)method.Physical fields and phase distribution under static state and rolling motion are compared to investigate the effect of rolling motion on the nucleate pool boiling process.The results show that rolling motion greatly influences the bubble behavior and void fraction owing to the differences between flow fields.The void fraction decreased by 11.84%,48.82%,and 56.87%as the maximum rolling angle increased from 15°to 45°,and by 11.84%,22.27%,and 21.81%as the rolling period increased from 1 s to 3 s.The void fraction decreased by 11.84%,48.82%,and 56.87%as the maximum rolling angle increased from 15°to 45°.The heat transfer coefficients of different cases are compared,and it is found that the effects of rolling motion on heat transfer coefficients can be ignored.展开更多
Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can b...Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.展开更多
In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the depend...In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the dependences of the heat flux on nanoparticle size and the nanoparticle volume fraction of the suspension, the fractal dimension of the nanoparticle and nucleation site, temperature of nanofluids and properties of fluids. The fractal model predictions show that the natural convection stage continues relatively longer in the case of nanofluids. The addition of nanoparticles causes a decrease of the pool nucleate boiling heat transfer. The nucleate pool boiling heat transfer coefficient is decreased by increasing particle concentration. An excellent agreement between the proposed model predictions and experimental data is found. The validity of the fractal model for nucleate pool boiling heat transfer is thus verified.展开更多
A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the c...A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the combination of three subprocesses:the transient heat conduction process in the solid heater,the evaporation of the microlayer underneath the bubble,and the bubble dynamics in the two-phase bulk fluid region.The moving bubble interface is captured by the volume of fluid method in the OpenFOAM framework.The proposed model is validated against the experimental results of the boiling process of the water on an Indium Tin Oxide heater.The predicted results agree well with related measurements in the literature.Following the validation,the effects of the boiling heat flux on the bubble departure period are examined.The results show that the bubble departure period decreases with the increase of the applied heat flux.High heat flux will cause irregularity in the departure periods for successive bubbles due to the influence of the wake flow evoked by the rising bubble.Furthermore,the influence of the bubble contact angle on the boiling heat-transfer performance is investigated.It is confirmed that the bubble departure diameter increases with the increase of the contact angle,meanwhile,the average wall temperature decreases with the increase of the contact angle.展开更多
In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can ...In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution'. However, the definition on fractal dimension given by Yang[1] is highly questionable, and the results obtained by Yang are contradictory to the basic fractal theory. Here are my comments:展开更多
Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. T...Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. The heat transfer mechanisms around stationary and moving bubbles on very thin microwires were analyzed numerically to evaluate the effect of the bubble motion on the heat transfer from the wire surface. The numerical analysis accurately models the experimentally observed bubble movement and fluid velocities. The analytical model includes the effects of the Marangoni flow around the bubble and the evaporation and condensation within the bubble. The analysis shows that the heat transfer was significantly enhanced by the Marangoni flow around the outside of the bubble which transfers at least twice as much en- ergy from the wire as the heat transfer directly from the wire to the bubble. The enhanced heat transfer due to the Marangoni flow was evident for both stationary and moving bubbles. The moving bubbles also created a wake that further enhanced the heat transfer from the wire. Since the Marangoni number for water is greater than for ethanol for the same conditions, the Marangoni flow and, hence, the bubble velocities are predicted to be greater in water than in ethanol.展开更多
Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circula...Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circulation is lower than for forced convections. The differences can be explained using second stir theory. The weak vortices and small stir energy in natural circulation systems result in nucleate boiling occurring earlier than in forced convection systems. In natural circulation systems high mass flow rates are accompa- nied by large kinetic energies and large stir energies, which enables changes in the directions of flow eddies and energy transport. The equilibrium vapor qualities at ONB are then higher at higher mass flow rates. The influence of other flow parameters on ONB can be evaluated by the relationships between these flow pa- rameters and the mass flow rate. The same values can lead to different results due to different eddy direc- tions. This indicates that the quantitative comparability in mathematics cannot be considered as only scien- tific standard. The second stir theory offers a new visual angle for researches on natural circulation.展开更多
In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with diffe...In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with different pore size (0.20 mm, 0.23 mm and 0.27 mm) were manufactured and tested using R-11, R-123 and R-134a. The pore size which yields the maximum heat transfer coefficient varied depending on the refrigerant. For R-134a, the maximum heat transfer coefficient was obtained for the tube having 0.27 nun pore size. For R-11 and R- 123, the optimum pore size was 0.23 mm. One novel feature of the present tubes is that their boiling curves do not show a cross-over characteristic, which existing pored tubes do. The connecting gaps of the present tube are believed to serve an additional route for the liquid supply and delay the dry-out of the tunnel. The present tubes yield the heat transfer coefficients approximately equal to those of the existing pored enhanced tubes. At the heat flux 40 kW/m2 and saturation temperature 4.4° C, the heat transfer coefficients of the present tubes are 6.5 times larger for R-11, 6.0 times larger for R-123 and 5.0 times larger for R-134a than that of the smooth tube展开更多
Thermodynamic and kinetic aspects of Sn nucleation and growth processes onto a glassy carbon electrode from SnCl2·2H2O dissolved in ethylene glycol solutions were studied.Typical reduction and oxidation peaks obs...Thermodynamic and kinetic aspects of Sn nucleation and growth processes onto a glassy carbon electrode from SnCl2·2H2O dissolved in ethylene glycol solutions were studied.Typical reduction and oxidation peaks observed in voltammograms have demonstrated the capability of ethylene glycol solutions to electrodeposit Sn.The temperature-dependence of diffusion coefficient values derived from potentiodynamic and potentiostatic studies helped to determine and validate estimations of the activation energy for Sn(II)bulk diffusion.Chronoamperometric results have identified that,the suitable model to describe the early stage of Sn electrodeposition could be composed of Sn three-dimensional nucleation and diffusion-controlled growth and water reduction contributions,which was duly validated by theoretical and experimental approaches.From the model,typical kinetic parameters such as the nucleation frequency of Sn(A),number density of Sn nuclei(N_(0)),and diffusion coefficient of Sn(II)ions(D),were determined.The presence of Sn nuclei with excellent quality and their structures were verified using SEM,EDX,and XRD techniques.展开更多
Sodium metal batteries(SMBs)are rising as viable alternatives to lithium-ion systems due to their superior energy density and sodium's relative abundance.However,SMBs face significant impediments,particularly the ...Sodium metal batteries(SMBs)are rising as viable alternatives to lithium-ion systems due to their superior energy density and sodium's relative abundance.However,SMBs face significant impediments,particularly the exceedingly high negative-to-positive capacity ratios(N/P ratios)which severely encumber energy density and hinder their practical application.Herein,a novel nucleophilic Na_(3)P interphase on aluminum foil has been designed to significantly lower the nucleation energy barrier for sodium atom deposition,resulting in a remarkable reduction of nucleation overpotential and efficient mitigation of dendritic growth at high sodium deposition of 5 mA h cm^(−2).The interphase promotes stable cycling in anode-less SMB configurations with a low N/P ratio of 1.4 and high cathode mass loading of 11.5 mg cm^(−2),and demonstrates a substantial increase in high capacity retention of 92.4%after 500 cycles even under 1 C rate condition.This innovation signifies a promising leap forward in the development of high-energy-density,anode-less SMBs,offering a potential solution to the longstanding issues of cycle stability and energy efficiency.展开更多
Biomineralization through microbial process has attracted great attention in the field of geotechnical engineering due to its ability to bind granular materials,clog pores,and seal fractures.Although minerals formed b...Biomineralization through microbial process has attracted great attention in the field of geotechnical engineering due to its ability to bind granular materials,clog pores,and seal fractures.Although minerals formed by biomineralization are generally the same as that by mineralization,their mechanical behaviors show a significant discrepancy.This study aims to figure out the differences between biomineralization and mineralization processes by visualizing and tracking the formation of minerals using microfluidics.Both biomineralization and mineralization processes occurred in the Y-shaped sandcontaining microchip that mimics the underground sand layers.Images from different areas in the reaction microchannel of microchips were captured to directly compare the distribution of minerals.Crystal size and numbers from different reaction times were measured to quantify the differences between biomineralization and mineralization processes in terms of crystal kinetics.Results showed that the crystals were precipitated in a faster and more uncontrollable manner in the mineralization process than that in the biomineralization process,given that those two processes presented similar precipitation stages.In addition,a more heterogeneous distribution of crystals was observed during the biomineralization process.The precipitation behaviors were further explained by the classical nucleation crystal growth theory.The present microfluidic tests could advance the understanding of biomineralization and provide new insight into the optimization of biocementation technology.展开更多
Controlling the content of athermal martensite and retained austenite is important to improving the mechanical properties of high-strength steels,but a mechanism for the accurate description of martensitic transformat...Controlling the content of athermal martensite and retained austenite is important to improving the mechanical properties of high-strength steels,but a mechanism for the accurate description of martensitic transformation during the cooling process must be addressed.At present,frequently used semi-empirical kinetics models suffer from huge errors at the beginning of transformation,and most of them fail to exhibit the sigmoidal shape characteristic of transformation curves.To describe the martensitic transformation process accurately,based on the Magee model,we introduced the changes in the nucleation activation energy of martensite with temperature,which led to the varying nucleation rates of this model during martensitic transformation.According to the calculation results,the relative error of the modified model for the martensitic transformation kinetics curves of Fe-C-X(X = Ni,Cr,Mn,Si) alloys reached 9.5% compared with those measured via the thermal expansion method.The relative error was approximately reduced by two-thirds compared with that of the Magee model.The incorporation of nucleation activation energy into the kinetics model contributes to the improvement of its precision.展开更多
基金Century Programme of Chinese Academy of Sciences.
文摘Heat transfer coefficients in nucleate pool boiling were measured on a horizontal copper surface for refrigerants, HFC-134a, HFC-32, and HFC-125, their binary and ternary mixtures under saturated conditions at 0.9MPa. Compared to pure components, both binary and ternary mixtures showed lower heat transfer coefficients.This deterioration was more pronounced as heat flux was increased. Experimental data were compared with some empirical and semi-empirical correlations available in literature. For binary mixture, the accuracy of the correlations varied considerably with mixtures and the heat flux. Experimental data for HFC-32/134a/125 were also compared with available correlated equation obtained by Thome. For ternary mixture, the boiling range of binary mixture composed by the pure fluids with the lowest and the medium boiling points, and their concentration difference had important effects on boiling heat transfer coefficients.
文摘A novel kind of multi-core magnetic composite particles, the surfaces of which were respectively mo- dified with goat-anti-mouse IgG and antitransferrin receptor（anti-CD71）, was prepared. The fetal nucleated red blood cells（FNRBCs） in the peripheral blood of a gravida were rapidly and effectively enriched and separated by the mo- dified multi-core magnetic composite particles in an external magnetic field. The obtained FNRBCs were used for the identification of the fetal sex by means of fluorescence in situ hybridization（FISH） technique. The results demonstrate that the multi-core magnetic composite particles meet the requirements for the enrichment and speration of FNRBCs with a low concentration and the accuracy of detetion for the diagnosis of fetal sex reached to 95%. Moreover, the obtained FNRBCs were applied to the non-invasive diagnosis of Down syndrome and chromosome 3p21 was de- tected. The above facts indicate that the novel multi-core magnetic composite particles-based method is simple, relia- ble and cost-effective and has opened up vast vistas for the potential application in clinic non-invasive prenatal diag- nosis.
文摘This paper presents results of an experimental investigation carried out to determine the effects of surface material on nucleate pool boiling heat transfer of refrigerant R113. Experiments were performed on horizontal circular plates of brass, copper and aluminum. The heat transfer coefficient was evaluated by measuring wall superheat and effective heat flux removed by boiling. The experiments were carried out in the heat flux range of 8 to 200 kW/m2. The obtained results have shown significant effect of surface material, with copper providing the highest heat transfer coefficient among the samples, and aluminum the least. There was negligible difference at low heat fluxes, but copper showed 23% better performance at high heat fluxes than aluminum and 18% better than brass.
文摘To find a simple, effective method of isolating fetal cells from maternal peripheral blood for prenatal diagnosis, 45 women were studied with their gestation being 6-14 weeks and age 21- 30 years. The fetal cells were isolated from maternal blood by using discontinuous density gradient centrifugation. Some of the isolated cells were made smear and counted under the microscope; others were used for predicting fetal sex by PCR amplification of Y chromosome specific DYZ1 gene. The major cells in the upper separation interface were lymphocytes and monocytes, with occasionally seen nucleated red blood cells (NRBC); while those in the middle separation interface were neutrocytes, with NRBC scattering. The ratio of NRBC/nucleated cells was 1. 98±0. 28× 10-5. There was no significant difference between the first and second trimester (P>0. 05). The amount of isolated fetal cells was sufficient for prenatal genetic diagnosis. Male pregnancy was correctly predicted in 10 out of 13 cases. It is concluded that the method of discontinuous density gradient centrifugation was of considerable importance in the development of non-invasive prenatal genetic diagnosis.
文摘Based on the tests of more than ten different additives, several effective additives are found capable of improving the boiling heat transfer behavior of water pronouncedly. The mechanism of the enhancement of nucleate boiling with additives has been investigated, and the results indicate that one of the important reasons is that the nucleation sites have been increased.
文摘In order to search for a more reliable method of sorting fetal nucleated red blood cells (NRBCs) and DNA from maternal peripheral blood and to identify origin of NRBCs and DNA, NRBCs were isolated from peripheral blood of 88 pregnant women by density gradient centrifugation and fluorescence activated cell sorter (FACS) respectively. Nested polymerase chain reaction was used to detect normal male SRY gene from blood plasma DNA of 65 pregnant women. The results revealed that fetal NRBCs were found in 14 of 27 maternal samples by density gradient centrifugation. The number of cells was from 1 to 10. Using FACS, CD71 + cells were identified among all 61 samples. The frequency was (0.35±0.25)×10 -2; The detectable rate of the SRY gene of blood plasma DNA from 46 women carrying male fetuses was 65.22 % (30/46). Non-detectable rate for 19 women carrying female fetuses was 94.74 % (18/19). It was concluded that the methods of sorting fetal NRBCs and DNA have already made great progress. The methods for fetal NRBCs and plasma DNA from maternal peripheral blood to diagnose genetic diseases seem to be the best methods of noninvasive prenatal diagnosis.
基金This project was supported by a grant from Science Foun-dation of Ministry of Public Heath of China (No. 96 .2 - 112 )and a grant from Hubei Provincial National Natural ScienceFoundation(96 J0 6 8)
文摘The single cell isolation technique was used to detect fetal nucleated erythroblasts at a single cell level from the peripheral blood of pregnant women in order to investigate the feasibility of this method for noninvasive prenatal diagnosis. Single fetal nucleated erythroblasts were isolated from the peripheral blood samples from 51 pregnant women by micromanipulation techniques after density gradient centrifugation. Nested polymerase chain reaction method was used to amplify the SRY gene. It was found that the concordance rate of amplification results with real fetal sex was 82.61 %. The sensitivity and specificity were 80 % and 87.50 % respectively. It was suggested that it is feasible and promising in non invasive prenatal diagnosis to detect fetal nucleated erythroblasts at a single cell level by using micromanipulation techniques.
基金Project supported by the National Natural Science Foundation of China (Grant Nos. 10375024 and 10775018)the Science Foundation of Hunan Educational Committee of China (Grant Nos. 08B028 and 06B057)the Natural Science Foundation of Hunan Province of China (Grant No. 08jj6043)
文摘With the aid of the critical size of colloidal cluster, the critical volume fraction of phase transition of colloidal system is determined by the principle of entropy maximum and Carnahan-Starling （CS） state equation in this paper. In our discussion, no parameter is introduced externally, and our results are in good agreement with the experimental results.
文摘Nucleate pool boiling process is widely used in heat exchangers because of its excellent heat transfer performance.With the gradual increase of applications,more and more equipments work in a non-static state,but there is little research under rolling conditions.Therefore,it is necessary to investigate the influence of rolling motion on the nucleate pool boiling process.In this study,a numerical investigation of the nucleate pool boiling process under static and rolling conditions is performed based on the volume-of-fluid(VOF)method.Physical fields and phase distribution under static state and rolling motion are compared to investigate the effect of rolling motion on the nucleate pool boiling process.The results show that rolling motion greatly influences the bubble behavior and void fraction owing to the differences between flow fields.The void fraction decreased by 11.84%,48.82%,and 56.87%as the maximum rolling angle increased from 15°to 45°,and by 11.84%,22.27%,and 21.81%as the rolling period increased from 1 s to 3 s.The void fraction decreased by 11.84%,48.82%,and 56.87%as the maximum rolling angle increased from 15°to 45°.The heat transfer coefficients of different cases are compared,and it is found that the effects of rolling motion on heat transfer coefficients can be ignored.
文摘Nucleate site distribution plays an essential role in nucleate boiling process. In this paper1 it is pointed out that the size and spatial distribution density of nucleate sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution function. It is further suggested that the surface micro geometry characteristics such as the shape of cavities should be described and analyzed qualitatively by using fractal theory.
基金Supported by the Scientific Research Special Foundation of Provincial University of Education Department of Fujian Province, China (Grant No.JK2009039)Sanming University (Grant No. HX200804)
文摘In this paper, a fractal model for nucleate pool boiling heat transfer of nanofluids is developed based on the fractal distribution of nanoparticles and nucleation sites on boiling surfaces. The model shows the dependences of the heat flux on nanoparticle size and the nanoparticle volume fraction of the suspension, the fractal dimension of the nanoparticle and nucleation site, temperature of nanofluids and properties of fluids. The fractal model predictions show that the natural convection stage continues relatively longer in the case of nanofluids. The addition of nanoparticles causes a decrease of the pool nucleate boiling heat transfer. The nucleate pool boiling heat transfer coefficient is decreased by increasing particle concentration. An excellent agreement between the proposed model predictions and experimental data is found. The validity of the fractal model for nucleate pool boiling heat transfer is thus verified.
基金the National Key Research and Development Program of China(Grant No.2013GB113005B)the the National Natural Science Foundation of China(Grant No.51976026)。
文摘A thermal-hydrodynamic coupling model is used to investigate the interplay between the wall temperature distribution and the bubble departure during the nucleate boiling process.The boiling process is modeled as the combination of three subprocesses:the transient heat conduction process in the solid heater,the evaporation of the microlayer underneath the bubble,and the bubble dynamics in the two-phase bulk fluid region.The moving bubble interface is captured by the volume of fluid method in the OpenFOAM framework.The proposed model is validated against the experimental results of the boiling process of the water on an Indium Tin Oxide heater.The predicted results agree well with related measurements in the literature.Following the validation,the effects of the boiling heat flux on the bubble departure period are examined.The results show that the bubble departure period decreases with the increase of the applied heat flux.High heat flux will cause irregularity in the departure periods for successive bubbles due to the influence of the wake flow evoked by the rising bubble.Furthermore,the influence of the bubble contact angle on the boiling heat-transfer performance is investigated.It is confirmed that the bubble departure diameter increases with the increase of the contact angle,meanwhile,the average wall temperature decreases with the increase of the contact angle.
文摘In recently published paper by Yang Chunxin[1], I reexamined the paper. On page 128, the paper 'pointed out that the size and spatial distribution density of nucleation sites presented on real boiling surface can be described by the normalized fractal distribution function, and the physical meaning of parameters involved in some experimental correlations proposed by early investigations are identified according to fractal distribution'. However, the definition on fractal dimension given by Yang[1] is highly questionable, and the results obtained by Yang are contradictory to the basic fractal theory. Here are my comments:
基金Supported by the National Natural Science Foundation of China (No. 50476014)
文摘Nucleate boiling is a very efficient method for generating high heat transfer rates from solid surfaces; however, the fundamental physical mechanisms governing nucleate boiling heat transfer are not well understood. The heat transfer mechanisms around stationary and moving bubbles on very thin microwires were analyzed numerically to evaluate the effect of the bubble motion on the heat transfer from the wire surface. The numerical analysis accurately models the experimentally observed bubble movement and fluid velocities. The analytical model includes the effects of the Marangoni flow around the bubble and the evaporation and condensation within the bubble. The analysis shows that the heat transfer was significantly enhanced by the Marangoni flow around the outside of the bubble which transfers at least twice as much en- ergy from the wire as the heat transfer directly from the wire to the bubble. The enhanced heat transfer due to the Marangoni flow was evident for both stationary and moving bubbles. The moving bubbles also created a wake that further enhanced the heat transfer from the wire. Since the Marangoni number for water is greater than for ethanol for the same conditions, the Marangoni flow and, hence, the bubble velocities are predicted to be greater in water than in ethanol.
基金Supported by the National Natural Science Foundation of China(No. 50976033)the National Key Laboratory of Bubble Physicsand Natural Circulation Funds
文摘Experimental data and calculated results for the onset of nucleate boiling （ONB） in natural circula- tion systems show that for the same operating conditions, the equilibrium vapor quality for ONB in natural circulation is lower than for forced convections. The differences can be explained using second stir theory. The weak vortices and small stir energy in natural circulation systems result in nucleate boiling occurring earlier than in forced convection systems. In natural circulation systems high mass flow rates are accompa- nied by large kinetic energies and large stir energies, which enables changes in the directions of flow eddies and energy transport. The equilibrium vapor qualities at ONB are then higher at higher mass flow rates. The influence of other flow parameters on ONB can be evaluated by the relationships between these flow pa- rameters and the mass flow rate. The same values can lead to different results due to different eddy direc- tions. This indicates that the quantitative comparability in mathematics cannot be considered as only scien- tific standard. The second stir theory offers a new visual angle for researches on natural circulation.
基金theR &D Management Center for Energy and Resources ofKorea
文摘In this study, pool boiling test results are provided for the structured enhanced tubes having pores with connecting gaps. The surface geometly of the present tube is similar to that of Turbo-B. Three tubes with different pore size (0.20 mm, 0.23 mm and 0.27 mm) were manufactured and tested using R-11, R-123 and R-134a. The pore size which yields the maximum heat transfer coefficient varied depending on the refrigerant. For R-134a, the maximum heat transfer coefficient was obtained for the tube having 0.27 nun pore size. For R-11 and R- 123, the optimum pore size was 0.23 mm. One novel feature of the present tubes is that their boiling curves do not show a cross-over characteristic, which existing pored tubes do. The connecting gaps of the present tube are believed to serve an additional route for the liquid supply and delay the dry-out of the tunnel. The present tubes yield the heat transfer coefficients approximately equal to those of the existing pored enhanced tubes. At the heat flux 40 kW/m2 and saturation temperature 4.4° C, the heat transfer coefficients of the present tubes are 6.5 times larger for R-11, 6.0 times larger for R-123 and 5.0 times larger for R-134a than that of the smooth tube
文摘Thermodynamic and kinetic aspects of Sn nucleation and growth processes onto a glassy carbon electrode from SnCl2·2H2O dissolved in ethylene glycol solutions were studied.Typical reduction and oxidation peaks observed in voltammograms have demonstrated the capability of ethylene glycol solutions to electrodeposit Sn.The temperature-dependence of diffusion coefficient values derived from potentiodynamic and potentiostatic studies helped to determine and validate estimations of the activation energy for Sn(II)bulk diffusion.Chronoamperometric results have identified that,the suitable model to describe the early stage of Sn electrodeposition could be composed of Sn three-dimensional nucleation and diffusion-controlled growth and water reduction contributions,which was duly validated by theoretical and experimental approaches.From the model,typical kinetic parameters such as the nucleation frequency of Sn(A),number density of Sn nuclei(N_(0)),and diffusion coefficient of Sn(II)ions(D),were determined.The presence of Sn nuclei with excellent quality and their structures were verified using SEM,EDX,and XRD techniques.
基金funding support from the National Natural Science Foundation of China (22125902, 22109150, 22279126, U2032202, and 21975243)the DNL cooperation Fund, CAS (DNL202020)+1 种基金the National Key R&D Program of China (no. 2022YFA1504101)the Anhui Provincial Natural Science Foundation (2108085QB65)
文摘Sodium metal batteries(SMBs)are rising as viable alternatives to lithium-ion systems due to their superior energy density and sodium's relative abundance.However,SMBs face significant impediments,particularly the exceedingly high negative-to-positive capacity ratios(N/P ratios)which severely encumber energy density and hinder their practical application.Herein,a novel nucleophilic Na_(3)P interphase on aluminum foil has been designed to significantly lower the nucleation energy barrier for sodium atom deposition,resulting in a remarkable reduction of nucleation overpotential and efficient mitigation of dendritic growth at high sodium deposition of 5 mA h cm^(−2).The interphase promotes stable cycling in anode-less SMB configurations with a low N/P ratio of 1.4 and high cathode mass loading of 11.5 mg cm^(−2),and demonstrates a substantial increase in high capacity retention of 92.4%after 500 cycles even under 1 C rate condition.This innovation signifies a promising leap forward in the development of high-energy-density,anode-less SMBs,offering a potential solution to the longstanding issues of cycle stability and energy efficiency.
基金We acknowledge the funding support from the National Natural Science Foundation of China(Grant Nos.51922024 and 52078085)Chongqing Talents Program,China(Grant No.cstc2021ycjhbgzxm0051).
文摘Biomineralization through microbial process has attracted great attention in the field of geotechnical engineering due to its ability to bind granular materials,clog pores,and seal fractures.Although minerals formed by biomineralization are generally the same as that by mineralization,their mechanical behaviors show a significant discrepancy.This study aims to figure out the differences between biomineralization and mineralization processes by visualizing and tracking the formation of minerals using microfluidics.Both biomineralization and mineralization processes occurred in the Y-shaped sandcontaining microchip that mimics the underground sand layers.Images from different areas in the reaction microchannel of microchips were captured to directly compare the distribution of minerals.Crystal size and numbers from different reaction times were measured to quantify the differences between biomineralization and mineralization processes in terms of crystal kinetics.Results showed that the crystals were precipitated in a faster and more uncontrollable manner in the mineralization process than that in the biomineralization process,given that those two processes presented similar precipitation stages.In addition,a more heterogeneous distribution of crystals was observed during the biomineralization process.The precipitation behaviors were further explained by the classical nucleation crystal growth theory.The present microfluidic tests could advance the understanding of biomineralization and provide new insight into the optimization of biocementation technology.
基金financially supported by the National Natural Science Foundation of China(No.U2102212)the Shanghai Rising-Star Program(No.21QA1403200)。
文摘Controlling the content of athermal martensite and retained austenite is important to improving the mechanical properties of high-strength steels,but a mechanism for the accurate description of martensitic transformation during the cooling process must be addressed.At present,frequently used semi-empirical kinetics models suffer from huge errors at the beginning of transformation,and most of them fail to exhibit the sigmoidal shape characteristic of transformation curves.To describe the martensitic transformation process accurately,based on the Magee model,we introduced the changes in the nucleation activation energy of martensite with temperature,which led to the varying nucleation rates of this model during martensitic transformation.According to the calculation results,the relative error of the modified model for the martensitic transformation kinetics curves of Fe-C-X(X = Ni,Cr,Mn,Si) alloys reached 9.5% compared with those measured via the thermal expansion method.The relative error was approximately reduced by two-thirds compared with that of the Magee model.The incorporation of nucleation activation energy into the kinetics model contributes to the improvement of its precision.
