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Internationalization of Higher Education:A Critical Literature Review of the UK Outward Student Mobility
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作者 GUO Yuxin 《Psychology Research》 2023年第10期484-493,共10页
The outward student mobility has been recognized as an instrument for the internationalization of higher education(IHE)world-widely and in the UK.This paper intends to critically review the existing literature in orde... The outward student mobility has been recognized as an instrument for the internationalization of higher education(IHE)world-widely and in the UK.This paper intends to critically review the existing literature in order to identify the current trend and issues of the UK outward student mobility under the IHE.It points out that the focus of current international educational activities is attracting foreign/inward students out of the economic impetus in the UK.Consequently,the outward student mobility is given the less recognition than the inward one in the UK policy-making and researches,which could lead the imbalanced gains for UK-domiciled students.Thus,it suggests that both the UK government education sectors and institutions should more develop the outward student mobility;moreover,future researches could investigate more about outward students’personal development. 展开更多
关键词 internationalization of higher education(IHE) UK outward student mobility policy-making agenda
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Outward Bound模式的演变轨迹与当代启示 被引量:1
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作者 王海波 《和田师范专科学校学报》 2013年第4期115-118,共4页
为了探寻适应我国国情的拓展训练模式,审视了20世纪40年代以来国外拓展训练四种模式的演化轨迹,在呈现出不同模式特点的基础上,分析不同模式的"共性"与"不足",借鉴其成功方法,归纳其启示思路,将有利于推进我国"... 为了探寻适应我国国情的拓展训练模式,审视了20世纪40年代以来国外拓展训练四种模式的演化轨迹,在呈现出不同模式特点的基础上,分析不同模式的"共性"与"不足",借鉴其成功方法,归纳其启示思路,将有利于推进我国"本土化"拓展训练模式的构建进程,进而促进我国拓展训练的全面发展。 展开更多
关键词 outward BOUND 模式 演变 启示
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The development of Fujian’s outward-oriented economy and its regional differentiation 被引量:1
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作者 CHEN Xiurong Institute of Geography, Chinese Academy of Sciences, Beijing 100101 CHINA 《Journal of Geographical Sciences》 SCIE CSCD 1998年第3期110-115,共6页
LocatedatthesoutheasterncoastofChina,Fujianwasoneoftheprovinceswhichwereearlieropenedtonavigationandhadtrade... LocatedatthesoutheasterncoastofChina,Fujianwasoneoftheprovinceswhichwereearlieropenedtonavigationandhadtraderelationswiththew... 展开更多
关键词 Fujian outward ORIENTED ECONOMY REGIONAL DIFFERENTIATION FOREIGN CAPITAL
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Effect of acupuncture combined with Xijing Tongmai decoction on the sustained expression of transient outward potassium channel related protein in rats with myocardial infarction 被引量:1
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作者 Jing-Xin Di Ying Wang Song-Feng Jin 《Journal of Hainan Medical University》 2021年第5期7-12,共6页
Objective:To observe the sustained expression of transient outward potassium channel related proteins at the end of the treatment and 30 days after the end of the treatment in rats,and to explore the sustained curativ... Objective:To observe the sustained expression of transient outward potassium channel related proteins at the end of the treatment and 30 days after the end of the treatment in rats,and to explore the sustained curative effect and mechanism of acupuncture combined with Xijingtongmai decoction in rats with myocardial infarction.Methods:Twenty of 130 male SD rats were random extracted as the control group,and the rest were used to establish myocardial infarction by fed with high-fat diet and then injected with isoproterenol.According to ECG,80 rats were successfully established.Then they were randomly divided into model group,acupuncture combined with Chinese medicine group,acupuncture group and Western medicine group.The content of bFGF protein was measured by ELISA.The protein contents of Kv1.4,Kv4.2,Kv4.3 and KChIP2 were measured by Western blot.Results:At the end of treatment,compared with the model group,the protein contents of Kv1.4,Kv4.2,Kv4.3,KChIP2 and bFGF in each treatment group increased,and the increase was most significant in the acupuncture combined with Chinese medicine group(P<0.05).At the end of treatment,compared with the model group,the protein contents of Kv1.4,Kv4.2,Kv4.3,KChIP2 and bFGF in each treatment group increased,and the increase was most significant in the acupuncture combined with Chinese medicine group(P<0.05).Compared with the treatment group at the end of treatment,the expression of Kv1.4,Kv4.2,Kv4.3,KChIP2 and bFGF protein in each treatment group 30 days after the end of treatment decreased slightly(P<0.05),but still higher than that of the model group at this time(P<0.05).The combination of acupuncture and Chinese medicine group decreased the least of them(P<0.05).Conclusion:The results showed that acupuncture combined with xijingtongmai decoction had a sustained good effect.Its sustained action mechanism may be achieved by continuously increasing the protein content of Kv1.4,Kv4.2,Kv4.3,KChIP2 and bFGF through transient outward potassium channel. 展开更多
关键词 Myocardial infarction Acupuncture treatment Xijing Tongmai decoction Transient outward potassium channel Sustained expression Sustained curative effect
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THE DEWLOPMENT OF OUTWARD ECONOMY IN RURAL ENTERPRISES AND THE DIFFERENCE AMONG PROVINCES
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作者 Fan Jie(Institute of Geography, CAS, Beijing 100101People’s Republic of China)Wolfgang Taubmann(Geography Deyartmemt,Bremen University, 28334 Bremen, Germany) 《Journal of Geographical Sciences》 SCIE CSCD 1996年第3期13-27,共15页
Rural wterprise plays a more and more important role in the development of outward economy of China. In 1994, 44.5 percent of the export value was produced by rural enterprises. This paper will focus on the rural ente... Rural wterprise plays a more and more important role in the development of outward economy of China. In 1994, 44.5 percent of the export value was produced by rural enterprises. This paper will focus on the rural enterprises with export, their growth, structural change and regional distribution. "San Lai Yi Bu" as a special form of outward enterprises, the foreign investment in rural enterprises the regional distribution and development tendency of rtral aterprises with foreign investment will be studied at the same time. The factor analysis will be used to study the evolution of the role that rural enterprises played in the development of outward economy, the regional difference in the development level and industrial structure of rural enterprises of outward economy. 展开更多
关键词 rural ENTERPRISES outward ECONOMY EXPORT enterprise with FOREIGN INVESTMENT FOREIGN INVESTMENT
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Impact of China’s Outward Foreign Direct Investment on Enterprise Performance
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作者 徐琦琦 王雷 ID Bouichou Said 《Journal of Donghua University(English Edition)》 EI CAS 2019年第5期513-520,共8页
The present study seeks to address two fundamental questions.(1)Does outward foreign direct investment(OFDI)enhance enterprise performance ultimately?(2)How does this effect come about?A new dataset from the years 201... The present study seeks to address two fundamental questions.(1)Does outward foreign direct investment(OFDI)enhance enterprise performance ultimately?(2)How does this effect come about?A new dataset from the years 2011 to 2016 based on the micro-data of 88 Chinese multinational-listed enterprises was used to test research hypotheses with the mediating effect modeling approach.The study results reveal that:(1)the investment intensity has a positive influence,while investment span has a negative influence on enterprise performance;(2)the enhanced innovation capability can considerably increase the enterprise performance,while investment intensity and span both hinder the upgrading of innovation capability;and(3)the innovation capability of an enterprise plays a partial intermediary role among investment span and enterprise performance.However,there is no mediating effect between investment intensity,innovation ability,and enterprise performance. 展开更多
关键词 outward FOREIGN direct investment(OFDI) ENTERPRISE performance INNOVATION CAPABILITY mediating effect
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Crustal Structure of the Chuan-Dian Block Revealed by Deep Seismic Sounding and its Implications for the Outward Expansion of the East Tibetan Plateau
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作者 XIONG Xiaosong WANG Guan +4 位作者 LI Qiusheng LU Zhanwu GAO Rui FENG Shaoying WU Guowei 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2022年第6期1932-1944,共13页
The Chuan-Dian Block(CDB)is located in the southeastern margin of the Tibetan Plateau,with a complex geological structure and active regional faults.The present tectonic condition with strong crustal deformation is cl... The Chuan-Dian Block(CDB)is located in the southeastern margin of the Tibetan Plateau,with a complex geological structure and active regional faults.The present tectonic condition with strong crustal deformation is closely related to the ongoing collision of the India and Eurasia plates since 65 Ma.The study of the crustal structure of this area is key to revealing the evolution and deep geodynamics of the lateral collision zone of the Tibetan Plateau.Deep seismic sounding is the most efficient method with which to unravel the velocity structure of the whole crust.Since the 1980s,19 deep seismic sounding profiles have been captured within the CDB area.In this study,we systematically integrate the research results of the 19 profiles in this area,then image the 3D crustal velocity,by sampling with a 5 km spacing and 2D/3D Kriging interpolation.The results show the following.(1)The Moho depth in the study area deepens from 30 km in the south to 66 km in the north,whereas there is no apparent variation from west to east.The Pn wave velocity is higher in stable tectonic units,such as 7.95 km/s in the Lanping-Simao block and 7.94 km/s in the western margin of the Yangtze block,than in active or mobile tectonic units,such as 7.81 km/s in the Baoshan block,7.72 km/s in the Tengchong block and 7.82 km/s in the Zhongdian block.(2)The crustal nature of the Tengchong block,the northern Lanping-Simao block and the Zhongdian block reflects a type of orogenic belt,having relatively strong tectonic activities,whereas the crustal nature of the central Lanping-Simao block and the western margin of the Yangtze block represents a type of platform.The different features of the upper-middle crust velocity,Moho depth and Pn wave velocity to both sides of the Red River fault zone and the Xianshuihe fault zone,reflect that they are clearly ultra-crustal.(3)Based on the distribution of the low velocity zones in the crust,the crustal material of the Tibetan Plateau is flowing in a NW–SE direction to the north of 26°N and to the west of 101°E,then diverting to flowing eastwards to the east of 101°E. 展开更多
关键词 deep seismic sounding crustal structure outward expansion Chuan-Dian Block southeastern margin of the Tibetan Plateau
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Outward-Bound Training的简介与应用 被引量:1
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作者 孙远刚 孙慕 《社会心理科学》 2015年第11期81-84,共4页
团体心理训练(Outward-bound Training)是一种塑造团队?激发个人成长的教学模式,通过对真实情景的模拟,以体验?启发为基本手段,目的是引导参与者将体会到训练项目中所蕴含的深刻道理与理念,同化到潜意识当中,最终体现于外在的人格?现如... 团体心理训练(Outward-bound Training)是一种塑造团队?激发个人成长的教学模式,通过对真实情景的模拟,以体验?启发为基本手段,目的是引导参与者将体会到训练项目中所蕴含的深刻道理与理念,同化到潜意识当中,最终体现于外在的人格?现如今这个竞争激烈的社会当中,拥有拥有良好的团队精神和积极进取的人生态度,是塑造现代人格特质的两大核心内涵? 展开更多
关键词 outward—Bound Training应用
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Impact of China’s outward foreign direct investment on environmental pollution in the home country
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作者 Guo Yang Qiang Zheng 《Chinese Journal of Population,Resources and Environment》 2021年第3期221-229,共9页
In the context of economic globalization and increasingly tight resource and environmental constraints,the environmental effect of open economy has been highly concerned by the academic community.With the implementati... In the context of economic globalization and increasingly tight resource and environmental constraints,the environmental effect of open economy has been highly concerned by the academic community.With the implementation of the“Going Global”campaign and the“Belt and Road Initiative”,China’s OFDI has been expanding.What is the impact of the rapid growth of OFDI on the home environment?How can China improve the quality and level of OFDI in order to promote domestic green development under the dual context of constructing a new dual circulation development pattern and advocating green development?These questions deserve further discussion.Most of the existing literature focuses on the empirical interpretation of OFDI’s home country environmental effect by using linear models,while few involve nonlinear models.The literature on the important role of financial development in home country and the threshold effect of OFDI on home country environment is even less common.In view of this,based on the mechanism of argumentation and propositional inference,this paper calculated the environmental pollution index of 30 provinces in China from 2003 to 2017 by using China’s provincial panel data of these years and selecting industrial waste water,industrial waste gas,industrial SO_(2),and industrial soot emissions and industrial solid waste production amount index.Then,this paper empirically studied China's OFDI home environment of financial development threshold effect by constructing financial development as the threshold variables panel threshold model.The results showed that:①China’s OFDI had a significant impact on the environment of the home country,based on the level of financial development of the home country.When China’s financial development level was lower than the first threshold value,China’s OFDI had a significant restraining effect on environmental pollution in the home country.When China’s financial development level crossed the first threshold value but did not exceed the second threshold value,China’s OFDI significantly enhanced its inhibiting effect on environmental pollution in its home country.When China’s financial development level was higher than the second threshold value,the inhibiting effect of China’s OFDI on environmental pollution in the home country was further enhanced.②In the sample period,the financial development level of most provinces in China was not high.Only a few provinces with high financial development level had a strong inhibiting effect on environmental pollution in their home country,and the provinces with a high degree of coupling and coordination between OFDI and financial development tended to have a low level of environmental pollution.Accordingly,this paper proposes to optimize the financial service environment of OFDI,improve the green technology content of OFDI,and strengthen the original innovation and re-innovation ability of green technology. 展开更多
关键词 Environmental pollution outward foreign direct investment Financial development Threshold model
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Environmental regulation,hidden economy,and China's outward foreign direct investment
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作者 Mengqi Gong Ming Yi +1 位作者 Haiyun Liu Xu Jiang 《Chinese Journal of Population,Resources and Environment》 2020年第1期35-41,共7页
The need to balance economic growth and its environmental impact continues to be a serious issue in China.As environmental regulation in China increases in importance,it is critical to understand how it impacts econom... The need to balance economic growth and its environmental impact continues to be a serious issue in China.As environmental regulation in China increases in importance,it is critical to understand how it impacts economic growth drivers such as outward foreign direct investment(OFDI)to formulate effective policies.One consideration should be the hidden economy,which can weaken the effects of environmental regulation on OFDI.This study investigates the scale of the hidden economy in 30 provinces and province-level municipalities in China in the period 2004 to 2015.The study uses the multiple indicators and multiple causes(MIMIC)model and the systematic generalized method of moments(GMM)test to analyze the impact of environmental regulation and the hidden economy on China's OFDI.The results show that stronger environmental regulation promotes OFDI.However,the hidden economy inhibits China's OFDI,as the positive effects of environmental regulation that drive OFDI are distorted.From a regional perspective,stronger environmental regulation promotes OFDI as well,while the hidden economy inhibits it.The interaction between environmental regulation and the hidden economy also inhibits it significantly. 展开更多
关键词 Environmental regulation Hidden economy outward foreign direct investment MIMIC model
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China’s Outward Foreign Direct Investment and Economic Growth in Developing Countries
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作者 潘春阳 吴青山 《China Economist》 2022年第3期113-124,共12页
The implementation of China’s open development strategy has unveiled a wave of outward foreign direct investment(OFDI)by Chinese companies,with global implications.Based on panel data from 146 developing countries fr... The implementation of China’s open development strategy has unveiled a wave of outward foreign direct investment(OFDI)by Chinese companies,with global implications.Based on panel data from 146 developing countries from 2003 to 2017,we investigate the growth effects of China’s OFDI.We find that China’s OFDI has promoted significant economic growth in developing countries.Not only could China’s OFDI increase GDP per capita of a country in a short time but raise the country’s long-run equilibrium value as well.In addition,the growth effects of China’s OFDI were more significant for countries with weak governance,rich resource,and modest human capital,and were above the average level for Belt and Road Initiative(BRI)countries,African countries,and in the post-crisis era.Our research helps unravel the global significance of Chinese companies investing overseas and contributes to research on the growth effects of direct investment between developing countries. 展开更多
关键词 outward foreign direct investment(OFDI) developing countries economic growth China
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The Significance and Practical Path of Outward Bound Training in College Physical Education Teaching
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作者 Liquan Chen You Li 《管理科学与研究(中英文版)》 2019年第1期22-26,共5页
Quality development training is a new type of experiential education mode implemented under the background of quality education. Strengthening the integration of quality development training and university sports requ... Quality development training is a new type of experiential education mode implemented under the background of quality education. Strengthening the integration of quality development training and university sports requires not only the sports reform of Chinese universities and colleges in the new era, but also the development of modern society. High quality application skills. Quality development training has important practical significance for university sports. This paper analyzes the relationship between quality development training and physics education in Chinese universities, and proposes two specific ways to combine the new era. 展开更多
关键词 outward TRAINING COLLEGE physical education MEANING Practice PATH
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China's Outward FDI in 2016 Hitting Another Historical Record High
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作者 Lynn Yu 《China's Foreign Trade》 2016年第6期16-17,共2页
According to EY 4th issue of its China outbound investment report'China Go Abroad—Key connectivity improvements along the Belt and Road in telecommunications&aviation sectors',and expects China’s outward... According to EY 4th issue of its China outbound investment report'China Go Abroad—Key connectivity improvements along the Belt and Road in telecommunications&aviation sectors',and expects China’s outward FDI in 2016 is likely to exceed 170 billion US dollars for the whole year and reach another historical record high.In the coming years,the tide of China’s overseas investment should continue to rise and maintain a double-digit growth rate. 展开更多
关键词 FDI China’s outward FDI in 2016 Hitting Another Historical Record High
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An Empirical Study on the Relationship Between the Scale of International Students from ASEAN and China’s Outward Foreign Direct Investment
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作者 Yan Jiali Cai Wenbo 《Contemporary Social Sciences》 2022年第1期17-31,共15页
With the further development of economic globalization since the establishment of ties between China and the Association of Southeast Asian Nations(ASEAN) 30 years ago and the continuous increase in the scale of inter... With the further development of economic globalization since the establishment of ties between China and the Association of Southeast Asian Nations(ASEAN) 30 years ago and the continuous increase in the scale of international students in China,the training of international talents has become an important approach to avoiding the risks of transnational investments.We established panel data by selecting variables from the period 2006 to 2017,including the scale of international students coming from ASEAN to China,the gross amount of China’s outward foreign direct investment(OFDI),and the GDP per capita of ASEAN countries to further explore the correlations among these variables.We applied a panel-vector autoregressive(PVAR) model to conducting a Granger causality test,a Gaussian mixture model(GMM) regression analysis,a Monte Carlo-based impulse response analysis,and variance decomposition of the data.The results show that the growth of OFDI exerted an obvious positive impact on the inflow of international students from the countries along the Belt and Road(B&R) within a short period,the growth of the scale of international students coming from these countries to study in China had a strong positive effect on OFDI,the training of international talents was conducive to promoting the scale of transnational investments,but the overall quality was not very high,and its economic contribution rate was low.It is also found that OFDI and the scale of international students from the countries along the B&R promoted the GDP growth to a certain extent and the positive accumulation effect fluctuated due to external factors.Therefore,it is suggested to expanding the scale of OFDI and improving China’s core competitiveness in international student education.Intensive management of investment factors should also be conducted along with sound development of training mechanisms for international talents. 展开更多
关键词 ASEAN scale of international students in China GDP per capita outward foreign direct investment
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Official Comments on China's outward investment and economic cooperation &foreign investment in China(1-11,2015)
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作者 Flora Zhao 《China Textile》 2016年第1期46-48,共3页
Editor’s note:Recently,official from the Department of Outward Investment and Economic Cooperation of the Ministry of Commerce has made comments on China’s outward investment and economic cooperation as well as fore... Editor’s note:Recently,official from the Department of Outward Investment and Economic Cooperation of the Ministry of Commerce has made comments on China’s outward investment and economic cooperation as well as foreign investment in JanuaryNovember.China’s Outward Investment and Economic Cooperation In January-November 2015,China’s outward investment and cooperation maintained a sound development momentum.The direct investment 展开更多
关键词 cooperation outward OVERSEAS OFFICIAL contract constantly MOMENTUM SIGNED struction maintained
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Outward Bound Training对师范类大学生自信心影响的研究
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作者 孙慕 孙远刚 《社会心理科学》 2015年第6期40-44,共5页
利用SCL-90、PEI对师范类大学生心理健康与自信心进行测试、比较和筛选,最后选取40名师范类大学生作为研究对象,并随机分成实验组和对照组。经过对筛选的对象进行3次辅导以后,实验组和对照组的结果显示:实验组的自信心显著高于对照组,... 利用SCL-90、PEI对师范类大学生心理健康与自信心进行测试、比较和筛选,最后选取40名师范类大学生作为研究对象,并随机分成实验组和对照组。经过对筛选的对象进行3次辅导以后,实验组和对照组的结果显示:实验组的自信心显著高于对照组,其中同人交谈维度有非常显著的提高,外表维度和爱情关系维度相较对照组也显著性提高,社会相互作用虽然有提升,差异并不显著,但是t值已接近显著临界值。实验组与对照组数据的差异对比,说明师范类大学生的自信心有较高的可塑性。实施可行的训练方法可以达到提升自信心的目的。 展开更多
关键词 outward BOUND TRAINING 师范类大学生 自信心
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Theoretical Explanation of China's Outward Direct Investment
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作者 裴长洪 樊瑛 《China Economist》 2010年第6期4-13,共10页
Traditional foreign direct investment (FDI) theory only examines corporate investment motivation while neglectinggovernment roles.China’s outward direct investment (ODI) is of both commercial and strategic significan... Traditional foreign direct investment (FDI) theory only examines corporate investment motivation while neglectinggovernment roles.China’s outward direct investment (ODI) is of both commercial and strategic significance to leveragedomestic and international resources and markets.ODI is a corporate behavior but also is a means of achieving nationalstrategies and heightening political and economic statuses.As a source of ODI,China should provide strong guidance andbacking to corporate ODI for both commercial and national interests. 展开更多
关键词 Foreign DIRECT INVESTMENT (FDI) national INTEREST INVESTMENT source outward DIRECT INVESTMENT (ODI)
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Effects of Volsartan on Transmural Heterogeneous Changes of Transient Outward Potassium Currents in Hypertrophic Cardiomyocytes in Rabbits 被引量:1
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作者 肖建民 付晖 +2 位作者 马业新 李泱 陆再英 《Journal of Huazhong University of Science and Technology(Medical Sciences)》 SCIE CAS 2004年第5期437-440,共4页
The transmural heterogeneous changes of transient outward potassium currents (Ito) in rabbit hypertrophic cardiaomyocytes and the effects of long-term prophylactic treatment with volsartan were investigated. Rabbits w... The transmural heterogeneous changes of transient outward potassium currents (Ito) in rabbit hypertrophic cardiaomyocytes and the effects of long-term prophylactic treatment with volsartan were investigated. Rabbits were divided into hypertrophy group (left ventricular hypertrophy induced by partial ligation of abdominal aorta), vol-treated group (volsartan was administrated after the ligation), and control group (sham operated). Myocytes were isolated by a two-step enzymatical method. The sub-endocardial (Endo) and sub-epicardium (Epi) tissues were separated from midmyocardium (Mid) with a razor. Whole-cell patch-clamp technique was used to record potassium currents. The results showed that membrane capacitance was larger in hypertrophic cells than those in control and vol-treated cells (P<0.01 vs control cells, n=30). The densities of Ito in hypertrophic cells were reduced by sub-epicardium (Epi) (27.8±2.9) %, midmyocardium (Mid) (41.0±4.7) %, and sub-endocardium (Endo) (20.3±3.4) % compared with those in control cells. The decrease of Ito density was more pronounced in Mid than in Epi and Endo (P<0.01 vs Epi or Endo). There were no significant differences in Ito densities between vol-treated group and control group in three layers separately. In conclusion, volsartan can inhibit the transmural heterogeneous changes of Ito in left ventricular hypertrophic cardiomyocytes in rabbit. 展开更多
关键词 透壁作用 不均匀变化 短暂性 钾离子 肥大性心肌症 心室疾病
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Characteristics of Transient Outward Potassium Channel Exposed to 3 mT Static Magnetic Field 被引量:1
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作者 李刚 程立君 +3 位作者 乔晓艳 林凌 张璐 李媛媛 《Transactions of Tianjin University》 EI CAS 2009年第5期319-323,共5页
Acutely isolated mouse hippocampal CA3 pyramidal neurons were exposed to 3 mT static magnetic field,and the characteristics of transient outward K+ channel were studied using the whole-cell patch-clamp technique.The e... Acutely isolated mouse hippocampal CA3 pyramidal neurons were exposed to 3 mT static magnetic field,and the characteristics of transient outward K+ channel were studied using the whole-cell patch-clamp technique.The experiment revealed that the amplitude of transient outward potassium channel current was reduced.The maximum activated current densities of control group and exposure group were 163.62±20.68 pA/pF and 98.74±16.57 pA/pF(n=12,P<0.01) respectively.The static magnetic field exposure affected the activation and inactivation process of transient outward potassium channel current.Due to the magnetic field exposure,the half-activation voltage of the activation curves changed from 5.59±1.96 mV to 27.87±7.24 mV(n=12,P<0.05) ,and the slope factor changed from 19.43±2.11 mV to 25.87±4.22 mV(n=12,P<0.05) .The half-inactivation voltage of the inactivation curves also changed from-56.09±0.89 mV to-57.16±1.10 mV(n=12,P>0.05) and the slope factor of the inactivation curves from 8.69±0.80 mV to 10.87±1.02 mV(n=12,P<0.05) .The results show that the static magnetic field can change the characteristics of transient outward K+ channel,and affect the physiological functions of neurons. 展开更多
关键词 钾通道 静磁场 MT 全细胞膜片钳技术 瞬间 海马CA3区 电流密度 电压曲线
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Two outward potassium current types are expressed during the neural differentiation of neural stem cells 被引量:3
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作者 Ruiying Bai Guowei Gao +1 位作者 Ying Xing Hong Xue 《Neural Regeneration Research》 SCIE CAS CSCD 2013年第28期2656-2665,共10页
The electrophysiological properties of potassium ion channels are regarded as a basic index for determining the functional differentiation of neural stem cells.In this study,neural stem cells from the hippocampus of n... The electrophysiological properties of potassium ion channels are regarded as a basic index for determining the functional differentiation of neural stem cells.In this study,neural stem cells from the hippocampus of newborn rats were induced to differentiate with neurotrophic growth factor,and the electrophysiological properties of the voltage-gated potassium ion channels were observed.Immunofluorescence staining showed that the rapidly proliferating neural stem cells formed spheres in vitro that expressed high levels of nestin.The differentiated neurons were shown to express neuron-specific enolase.Flow cytometric analysis revealed that the neural stem cells were actively dividing and the percentage of cells in the S+G2/M phase was high.However,the ratio of cells in the S+G2/M phase decreased obviously as differentiation proceeded.Whole-cell patch-clamp recordings revealed apparent changes in potassium ion currents as the neurons differentiated.The potassium ion currents consisted of one transient outward potassium ion current and one delayed rectifier potassium ion current,which were blocked by 4-aminopyridine and tetraethylammonium,respectively.The experimental findings indicate that neural stem cells from newborn rat hippocampus could be cultured and induced to differentiate into functional neurons under defined conditions in vitro.The differentiated neurons expressed two types of outward potassium ion currents similar to those of mature neurons in vivo. 展开更多
关键词 神经干细胞 分化过程 钾电流 神经元特异性烯醇化酶 类型 钾离子通道 流式细胞仪分析 免疫荧光染色
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