Peanut stem rot caused by Sclerotium rolfsii is a soil-borne disease,and it has become the main disease of peanut in Yimeng mountainous area.S.rolfsii survives the winter as mycelia and sclerotia in soil and debris,be...Peanut stem rot caused by Sclerotium rolfsii is a soil-borne disease,and it has become the main disease of peanut in Yimeng mountainous area.S.rolfsii survives the winter as mycelia and sclerotia in soil and debris,becoming the primary source of infection in the following year.The disease resistance of peanut varieties,high temperature and humidity,and cultivation measures are the pathogenic factors affecting the occurrence of peanut stem rot.The disease can be effectively controlled by screening disease-resistant varieties and seed chemical treatment,improving soil by deep tillage and crop rotation,carrying out flowing water management of affected field,cutting off transmission routes,and strengthening seed dressing and triple spraying control.展开更多
Ustilaginoidea virens is the causal agent of rice false smut,which can be a highly destructive disease of rice.The plasma membrane phosphatase Psr1 proteins,which act as a regulator of the salinity stress response in ...Ustilaginoidea virens is the causal agent of rice false smut,which can be a highly destructive disease of rice.The plasma membrane phosphatase Psr1 proteins,which act as a regulator of the salinity stress response in yeast,are widely distributed across fungi,but their functional characterization is sketchy.In this study,we characterized the functions of Psr1 protein,UvPsr1,in U.virens.Analyses of the AUvpsr1 and its complementation strain showed that UvPsr1 is required for normal mycelial growth,conidiation and tolerance to oxidative,osmotic and cell wall stresses.When rice panicles were inoculated with the AUvpsr1 strains,no symptoms of false smut disease developed,showing that UvPSR1 also contributes to the pathogenicity of the fungus.The deletion mutant of UvPSR1 also appeared to produce a smaller titer of toxic compounds able to inhibit elongation of the germinated seeds.In conclusion,our results indicated that UvPsr1 is a new pathogenic factor of U.virens.展开更多
Through the review of relevant literature in recent years,it is found that the incidence rate of metabolic diseases in rural areas is on the rise:The related factors that may cause diseases include diet structure,exer...Through the review of relevant literature in recent years,it is found that the incidence rate of metabolic diseases in rural areas is on the rise:The related factors that may cause diseases include diet structure,exercise habits,medical resources and other aspects.At the same time,there are some limitations in the intervention and treatment measures of this kind of disease.It is urgent to carry out in-depth exploration for the special conditions in rural areas.By reviewing the research progress related to metabolic diseases in rural areas,more new ideas are provided for the treatment and improvement of metabolic diseases in rural areas.展开更多
Malignant lymphoma originates from the lymphohematopoietic system.It can occur in any lymphoid tissue.Malignant lymphoma of the salivary gland is rare,but its incidence has increased in recent years.Its clinical-prese...Malignant lymphoma originates from the lymphohematopoietic system.It can occur in any lymphoid tissue.Malignant lymphoma of the salivary gland is rare,but its incidence has increased in recent years.Its clinical-presentations are nonspecific,and it is often manifested as a painless mass in a salivary gland,which can be accompanied by multiple swollen cervical lymph nodes.Confirmation of the diagnosis before an invasive procedure is difficult.Clinically,malignant lymphoma of the salivary gland tends to be misdiagnosed,leading to an inappropriate treatment plan and the ultimate delay in the optimal treatment of the disease.This article reviews the pathogenesis,clinical features,imaging findings,diagnosis,treatment and prognosis of malignant lymphoma of the salivary gland.展开更多
Stem bleeding disease of coconut(Cocos nucifera L.)is an important disease in main coconut producing areas in China.This article reviews taxonomic status and biological characteristics of Ceratocystis paradoxa,as well...Stem bleeding disease of coconut(Cocos nucifera L.)is an important disease in main coconut producing areas in China.This article reviews taxonomic status and biological characteristics of Ceratocystis paradoxa,as well as the occurrence regularity,pathogenic factors,propagation path and integrated control methods of stem bleeding disease of coconut.The main problems in the study of stem bleeding disease are summarized,and the future research directions are prospected.展开更多
The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the cl...The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the clinical experiences in tumor treatment of Dr.Chen Shizhou,a well-known traditional Chinese medicine expert in Weifang City,Shandong Province.He put forward the treatment method of"replenishing Qi and nourishing blood,detoxicating and resolving masses",paying attention to protecting stomach qi and advocating survival with tumor,with remarkable clinical effects.展开更多
Objective:The objective of this study is to explore the treatment and compatibility principles of Traditional Chinese Medicine.Materials and Methods:Syndrome differentiation is used to identify the etiology,nature,and...Objective:The objective of this study is to explore the treatment and compatibility principles of Traditional Chinese Medicine.Materials and Methods:Syndrome differentiation is used to identify the etiology,nature,and location of a disease and the relationship between the healthy Qi and pathogenic factors by analyzing and synthesizing the four diagnostics data.The theory of treatment is to determine the principle and methods of treatment according to the results of syndrome differentiation and implement them as a specific prescription.This paper bears witness to the principle universality by analysis of the articles of the Banxia Xiexin Decoction,and it equally has analogical prescriptions in Treatise on Febrile Diseases.Results:The treatment and compatibility principles of Traditional Chinese Medicine are the same,that is,rectifying the deviation on three dimensions,strengthening the healthy Qi,and eliminating pathogenic factors in the light of its general trend.Conclusion:The treatment and compatibility principles of Traditional Chinese Medicine are the same,The treatment and compatibility principles provide a new thinking for clinical treatment.展开更多
As an emerging research field of brain science,multimodal data fusion analysis has attracted broader attention in the study of complex brain diseases such as Parkinson's disease(PD).However,current studies primari...As an emerging research field of brain science,multimodal data fusion analysis has attracted broader attention in the study of complex brain diseases such as Parkinson's disease(PD).However,current studies primarily lie with detecting the association among different modal data and reducing data attributes.The data mining method after fusion and the overall analysis framework are neglected.In this study,we propose a weighted random forest(WRF)model as the feature screening classifier.The interactions between genes and brain regions are detected as input multimodal fusion features by the correlation analysis method.We implement sample classification and optimal feature selection based on WRF,and construct a multimodal analysis framework for exploring the pathogenic factors of PD.The experimental results in Parkinson's Progression Markers Initiative(PPMI)database show that WRF performs better compared with some advanced methods,and the brain regions and genes related to PD are detected.The fusion of multi-modal data can improve the classification of PD patients and detect the pathogenic factors more comprehensively,which provides a novel perspective for the diagnosis and research of PD.We also show the great potential of WRF to perform the multimodal data fusion analysis of other brain diseases.展开更多
基金Peanut Innovation Team Project of Shandong Agricultural Industry Research System(SDAIT-05-022)Special Fund Project of Agricultural Technology Extension of Shandong Province(SDTG-2016-08).
文摘Peanut stem rot caused by Sclerotium rolfsii is a soil-borne disease,and it has become the main disease of peanut in Yimeng mountainous area.S.rolfsii survives the winter as mycelia and sclerotia in soil and debris,becoming the primary source of infection in the following year.The disease resistance of peanut varieties,high temperature and humidity,and cultivation measures are the pathogenic factors affecting the occurrence of peanut stem rot.The disease can be effectively controlled by screening disease-resistant varieties and seed chemical treatment,improving soil by deep tillage and crop rotation,carrying out flowing water management of affected field,cutting off transmission routes,and strengthening seed dressing and triple spraying control.
基金This research was funded by Zhejiang Provincial Natural Science Foundation of China(Grant No.LQ19C140004)Key Research and Development Project of Zhejiang Province(Grant No.2019C02018)the Chinese Academy of Agricultural Sciences under the‘Elite Youth’program,and the Agricultural Sciences and Technologies Innovation Program.We thank Prof.HUANG Junbin of Huazhong Agriculture University(Wuhan,China)for providing inoculum of the U.virens strain HWD-2.
文摘Ustilaginoidea virens is the causal agent of rice false smut,which can be a highly destructive disease of rice.The plasma membrane phosphatase Psr1 proteins,which act as a regulator of the salinity stress response in yeast,are widely distributed across fungi,but their functional characterization is sketchy.In this study,we characterized the functions of Psr1 protein,UvPsr1,in U.virens.Analyses of the AUvpsr1 and its complementation strain showed that UvPsr1 is required for normal mycelial growth,conidiation and tolerance to oxidative,osmotic and cell wall stresses.When rice panicles were inoculated with the AUvpsr1 strains,no symptoms of false smut disease developed,showing that UvPSR1 also contributes to the pathogenicity of the fungus.The deletion mutant of UvPSR1 also appeared to produce a smaller titer of toxic compounds able to inhibit elongation of the germinated seeds.In conclusion,our results indicated that UvPsr1 is a new pathogenic factor of U.virens.
基金Supported by 2023 Jilin Province College Student Innovation and Entrepreneurship Training Program(S202310199042)Jilin Province Science and Technology Development Plan Project(YDZJ202201ZYTS195)+1 种基金2022 Jilin Province Traditional Chinese Medicine Technology Project(2022128)Youth Excellent Discipline Backbone Training Project in Changchun University of Chinese Medicine(202304).
文摘Through the review of relevant literature in recent years,it is found that the incidence rate of metabolic diseases in rural areas is on the rise:The related factors that may cause diseases include diet structure,exercise habits,medical resources and other aspects.At the same time,there are some limitations in the intervention and treatment measures of this kind of disease.It is urgent to carry out in-depth exploration for the special conditions in rural areas.By reviewing the research progress related to metabolic diseases in rural areas,more new ideas are provided for the treatment and improvement of metabolic diseases in rural areas.
基金Supported by the 345 Talent Project of Shengjing Hospitalthe Natural Science Foundation of Liaoning Province,No.20170541042.
文摘Malignant lymphoma originates from the lymphohematopoietic system.It can occur in any lymphoid tissue.Malignant lymphoma of the salivary gland is rare,but its incidence has increased in recent years.Its clinical-presentations are nonspecific,and it is often manifested as a painless mass in a salivary gland,which can be accompanied by multiple swollen cervical lymph nodes.Confirmation of the diagnosis before an invasive procedure is difficult.Clinically,malignant lymphoma of the salivary gland tends to be misdiagnosed,leading to an inappropriate treatment plan and the ultimate delay in the optimal treatment of the disease.This article reviews the pathogenesis,clinical features,imaging findings,diagnosis,treatment and prognosis of malignant lymphoma of the salivary gland.
基金Supported by Hainan Natural Science Foundation(2019RC339)Key Project of Hainan Province(ZDYF2019072)Basic Research Project of CATAS(16301520190010).
文摘Stem bleeding disease of coconut(Cocos nucifera L.)is an important disease in main coconut producing areas in China.This article reviews taxonomic status and biological characteristics of Ceratocystis paradoxa,as well as the occurrence regularity,pathogenic factors,propagation path and integrated control methods of stem bleeding disease of coconut.The main problems in the study of stem bleeding disease are summarized,and the future research directions are prospected.
文摘The pathogenesis of malignant tumors is the deficiency of vital Qi and the excess of pathogenic Qi.Its basic treating principle is to strengthen vital Qi to eliminate pathogenic factor.The paper is to summarize the clinical experiences in tumor treatment of Dr.Chen Shizhou,a well-known traditional Chinese medicine expert in Weifang City,Shandong Province.He put forward the treatment method of"replenishing Qi and nourishing blood,detoxicating and resolving masses",paying attention to protecting stomach qi and advocating survival with tumor,with remarkable clinical effects.
文摘Objective:The objective of this study is to explore the treatment and compatibility principles of Traditional Chinese Medicine.Materials and Methods:Syndrome differentiation is used to identify the etiology,nature,and location of a disease and the relationship between the healthy Qi and pathogenic factors by analyzing and synthesizing the four diagnostics data.The theory of treatment is to determine the principle and methods of treatment according to the results of syndrome differentiation and implement them as a specific prescription.This paper bears witness to the principle universality by analysis of the articles of the Banxia Xiexin Decoction,and it equally has analogical prescriptions in Treatise on Febrile Diseases.Results:The treatment and compatibility principles of Traditional Chinese Medicine are the same,that is,rectifying the deviation on three dimensions,strengthening the healthy Qi,and eliminating pathogenic factors in the light of its general trend.Conclusion:The treatment and compatibility principles of Traditional Chinese Medicine are the same,The treatment and compatibility principles provide a new thinking for clinical treatment.
基金This work was supported by the National Natural Science Foundation of China under Grant No.62072173the Natural Science Foundation of Hunan Province of China under Grant No.2020JJ4432+3 种基金the Key Scientific Research Projects of Department of Education of Hunan Province under Grant No.20A296the Degree and Postgraduate Education Reform Project of Hunan Province under Grant No.2019JGYB091Hunan Provincial Science and Technology Project Foundation under Grant No.2018TP1018,and the InnovationEntrepreneurship Training Program of Hunan Xiangjiang Artificial Intelligence Academy.
文摘As an emerging research field of brain science,multimodal data fusion analysis has attracted broader attention in the study of complex brain diseases such as Parkinson's disease(PD).However,current studies primarily lie with detecting the association among different modal data and reducing data attributes.The data mining method after fusion and the overall analysis framework are neglected.In this study,we propose a weighted random forest(WRF)model as the feature screening classifier.The interactions between genes and brain regions are detected as input multimodal fusion features by the correlation analysis method.We implement sample classification and optimal feature selection based on WRF,and construct a multimodal analysis framework for exploring the pathogenic factors of PD.The experimental results in Parkinson's Progression Markers Initiative(PPMI)database show that WRF performs better compared with some advanced methods,and the brain regions and genes related to PD are detected.The fusion of multi-modal data can improve the classification of PD patients and detect the pathogenic factors more comprehensively,which provides a novel perspective for the diagnosis and research of PD.We also show the great potential of WRF to perform the multimodal data fusion analysis of other brain diseases.
