Three new complexes TbL3dipy （H2O）2, TbL3phen （H2O） 2 and TbL2 （TPPO） 2NO3 were synthesized （L = phenylglyoxylate ion, dipy = 2, 2-dipyridine, phen = 1,10-phenanthmline, TPPO = Triphenyl phosphine oxide）. Elem...Three new complexes TbL3dipy （H2O）2, TbL3phen （H2O） 2 and TbL2 （TPPO） 2NO3 were synthesized （L = phenylglyoxylate ion, dipy = 2, 2-dipyridine, phen = 1,10-phenanthmline, TPPO = Triphenyl phosphine oxide）. Elemental analysis, conductivity, IR spectra, and ^1HNMR spectra studies were performed. IR spectra indicate that the carboxylate ion of phenylglyoxylate is coordinated to the Tb（Ⅲ） ion as an unidentate ligand. In ^1HNMR, the signals of different hydrogens in phenylglyoxylate ion shift upfield. The excitation and emission spectra of the three solid complexes were recorded at morn temperature, in which the optimum excitation wavelengths are, 361.0, 359.0 and 367.0 nm for these three complexes, respectively. Four emission bands due to the ^5D4-^7Fj（j = 6, 5, 4, 3） transitions were observed for TbL3dipy（H2O）2（489.0, 545.0, 584.0, 620.0 nm） and TbL3phen（H2O）2（490.0, 544.0, 583.0, 620.0 nm）. Under the same conditions, only one emission band due to the ^5D4-^7F5 transition was observed for the complex TbL2（TPPO）2NO3. The emission intensity of TbL3dipy（H2O）2 is the strongest among the three complexes.展开更多
Three new complexes TbL3dipy （H2O）2, TbL3phen （ H2O ）2 and TbL2 （ TPPO ）2NO3 have been synthesized （L = phenylglyoxylate ion, dipy = 2, 2- dipyfidine, phen = 1,10-phenanthroline, TPPO = Triphenyl phosphine oxi...Three new complexes TbL3dipy （H2O）2, TbL3phen （ H2O ）2 and TbL2 （ TPPO ）2NO3 have been synthesized （L = phenylglyoxylate ion, dipy = 2, 2- dipyfidine, phen = 1,10-phenanthroline, TPPO = Triphenyl phosphine oxide ）. Elemental analysis, conductivity, IR spectra and ^1HNMR spectra studies were performed on them. IR spectra indicate that carboxylate ions in the phenylglyoxylate are coordinated to Tb （Ⅲ） ions as unidentate ligands. In ^1HNMR, the signals of hydrogens in phenylglyoxylate shift upfield. The excitation and emission spectra of the three comolexes were recorded at room temoerature, the excitation spectra show that the optimum excitation wavelengths are 361.0, 359.0 and 367.0 nm, respectively. Four emission bands due to ^5D4-^7Fj （j = 6, 5, 4, 3 ） transitions were observed for TbLadipy （ H2O ）2 （489.0, 545. 0, 584.0,620.0 nm） and TbL3phen （H2O）2 （490. , 544.0, 583.0, 620.0 nm）. And under the same conditions, only one emission band due to ^5Da-^7F5 transition was observed for TbL2 （TPPO）ENO3. The emission intensity of TbLadipy （H2O）2 is the strongest among the three complexes.展开更多
A bacterium strain B26 capable of producing(R)-α-hydroxyphenylacetic acid [(R)-HPA](yield,47.5%;enantiomeric excess,99.1%) from phenylglyoxylic acid(PGA) with high optical purity was isolated and identified as Bacill...A bacterium strain B26 capable of producing(R)-α-hydroxyphenylacetic acid [(R)-HPA](yield,47.5%;enantiomeric excess,99.1%) from phenylglyoxylic acid(PGA) with high optical purity was isolated and identified as Bacillus sp.B26 by 16S rDNA(ribosomal DNA) sequencing.Phylogenic analysis showed that the strain was most similar to Bacillus sp.enrichment culture clone SYW5(FJ601635.1) and Bacillus cereus strain FM-4(EU794727.1).Efforts were made to further improve HPA-production and PGA-tolerance by UV irradiation and UV-LiCl cooperative mutagenesis.Among viable mutants,B.sp.UV-38 and B.sp.ULi-11 exhibited better productivities than the wild type.Comparisons of HPA production and time course among wild strain and two mutants showed that B.sp.ULi-11 was more competent than B.sp.UV-38.HPA production was increased by 39.1% with B.sp.ULi-11(yield,65.4%) compared to that with B.sp.B26(yield,47.0%) when cultured in fermentation broth(pH 7.2) at 32℃ with an agitation speed of 180 r·min-1 and PGA final concentration of 15 mmol·L-1 for 25 h.展开更多
In this study, we selected 58 styrene-exposed workers, measured personal styrene exposure, evaluated genotypes relevant drug-metabolizing enzymes (CYP2E1, EPHX1, GSTM1 and GSTT1) which may explain the variability in t...In this study, we selected 58 styrene-exposed workers, measured personal styrene exposure, evaluated genotypes relevant drug-metabolizing enzymes (CYP2E1, EPHX1, GSTM1 and GSTT1) which may explain the variability in the urinary metabolite excretion. The results showed that, in different levels of styrene exposure groups, there is a significant association between urinary metabolites and some genotypes of styrene-metabolizing enzymes, including CYP2E1 (5-flanking region, RsaI/PstI), GSTM1(gene deletions) and EPHX1(predicted activity).展开更多
文摘Three new complexes TbL3dipy （H2O）2, TbL3phen （H2O） 2 and TbL2 （TPPO） 2NO3 were synthesized （L = phenylglyoxylate ion, dipy = 2, 2-dipyridine, phen = 1,10-phenanthmline, TPPO = Triphenyl phosphine oxide）. Elemental analysis, conductivity, IR spectra, and ^1HNMR spectra studies were performed. IR spectra indicate that the carboxylate ion of phenylglyoxylate is coordinated to the Tb（Ⅲ） ion as an unidentate ligand. In ^1HNMR, the signals of different hydrogens in phenylglyoxylate ion shift upfield. The excitation and emission spectra of the three solid complexes were recorded at morn temperature, in which the optimum excitation wavelengths are, 361.0, 359.0 and 367.0 nm for these three complexes, respectively. Four emission bands due to the ^5D4-^7Fj（j = 6, 5, 4, 3） transitions were observed for TbL3dipy（H2O）2（489.0, 545.0, 584.0, 620.0 nm） and TbL3phen（H2O）2（490.0, 544.0, 583.0, 620.0 nm）. Under the same conditions, only one emission band due to the ^5D4-^7F5 transition was observed for the complex TbL2（TPPO）2NO3. The emission intensity of TbL3dipy（H2O）2 is the strongest among the three complexes.
文摘Three new complexes TbL3dipy （H2O）2, TbL3phen （ H2O ）2 and TbL2 （ TPPO ）2NO3 have been synthesized （L = phenylglyoxylate ion, dipy = 2, 2- dipyfidine, phen = 1,10-phenanthroline, TPPO = Triphenyl phosphine oxide ）. Elemental analysis, conductivity, IR spectra and ^1HNMR spectra studies were performed on them. IR spectra indicate that carboxylate ions in the phenylglyoxylate are coordinated to Tb （Ⅲ） ions as unidentate ligands. In ^1HNMR, the signals of hydrogens in phenylglyoxylate shift upfield. The excitation and emission spectra of the three comolexes were recorded at room temoerature, the excitation spectra show that the optimum excitation wavelengths are 361.0, 359.0 and 367.0 nm, respectively. Four emission bands due to ^5D4-^7Fj （j = 6, 5, 4, 3 ） transitions were observed for TbLadipy （ H2O ）2 （489.0, 545. 0, 584.0,620.0 nm） and TbL3phen （H2O）2 （490. , 544.0, 583.0, 620.0 nm）. And under the same conditions, only one emission band due to ^5Da-^7F5 transition was observed for TbL2 （TPPO）ENO3. The emission intensity of TbLadipy （H2O）2 is the strongest among the three complexes.
基金Supported by the Specialized Research Fund for the Doctoral Program of Higher Education of China (20103514110002)the Science and Technology Key Project of Fujian Province (2009N0046)
文摘A bacterium strain B26 capable of producing(R)-α-hydroxyphenylacetic acid [(R)-HPA](yield,47.5%;enantiomeric excess,99.1%) from phenylglyoxylic acid(PGA) with high optical purity was isolated and identified as Bacillus sp.B26 by 16S rDNA(ribosomal DNA) sequencing.Phylogenic analysis showed that the strain was most similar to Bacillus sp.enrichment culture clone SYW5(FJ601635.1) and Bacillus cereus strain FM-4(EU794727.1).Efforts were made to further improve HPA-production and PGA-tolerance by UV irradiation and UV-LiCl cooperative mutagenesis.Among viable mutants,B.sp.UV-38 and B.sp.ULi-11 exhibited better productivities than the wild type.Comparisons of HPA production and time course among wild strain and two mutants showed that B.sp.ULi-11 was more competent than B.sp.UV-38.HPA production was increased by 39.1% with B.sp.ULi-11(yield,65.4%) compared to that with B.sp.B26(yield,47.0%) when cultured in fermentation broth(pH 7.2) at 32℃ with an agitation speed of 180 r·min-1 and PGA final concentration of 15 mmol·L-1 for 25 h.
文摘In this study, we selected 58 styrene-exposed workers, measured personal styrene exposure, evaluated genotypes relevant drug-metabolizing enzymes (CYP2E1, EPHX1, GSTM1 and GSTT1) which may explain the variability in the urinary metabolite excretion. The results showed that, in different levels of styrene exposure groups, there is a significant association between urinary metabolites and some genotypes of styrene-metabolizing enzymes, including CYP2E1 (5-flanking region, RsaI/PstI), GSTM1(gene deletions) and EPHX1(predicted activity).
