Objective: to study the influence of Chinese medicines for promoting blood circulation to remove blood stasis on fibrinogen (FIB) and D-dimer (DD) in plasma of patients with cerebral thrombosis. Method: 73 inpatients ...Objective: to study the influence of Chinese medicines for promoting blood circulation to remove blood stasis on fibrinogen (FIB) and D-dimer (DD) in plasma of patients with cerebral thrombosis. Method: 73 inpatients with acute cerebral thrombosis were randomly divided into a control group of 34 cases and a treatment group of 39 cases. The content of FIB and DD in plasma was detected before treatment and on the 7th and 14th days after treatment. Result: FIB content in plasma after treatment was lower than that before treatment in the control group (P<0.01) and more remarkable in the treatment group (P<0.001). There was an obvious difference in DD content before and after treatment in both groups. DD content on the 7th and 14th days after treatment in the treatment group was obviously higher than that in the control group (P<0.01 and P<0.05 respectively). Conclusion: Chinese medicines for promoting blood circulation to remove blood stasis can reduce the FIB content in plasma of patients with cerebral thrombosis, raise the DD content in plasma, cause the peak of DD content appear earlier and obviously improve hypercoagulability of blood in patients with cerebral thrombosis.展开更多
目的:观察醒脑静对急性脑出血患者血浆FIB、DD、TNF-α水平的影响。方法:选取88例急性脑出血患者为研究对象,以随机数字表法分成观察组和对照组各44例。对照组给予常规治疗,观察组在对照组的基础上给予醒脑静治疗。比较两组患者治疗前...目的:观察醒脑静对急性脑出血患者血浆FIB、DD、TNF-α水平的影响。方法:选取88例急性脑出血患者为研究对象,以随机数字表法分成观察组和对照组各44例。对照组给予常规治疗,观察组在对照组的基础上给予醒脑静治疗。比较两组患者治疗前后血浆纤维蛋白原(Fibrinogen,FIB)、D-二聚体(D-Dimer,D-D)、肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)水平、美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分、格拉斯哥昏迷(Glasgow Coma Scale,GCS)评分及临床疗效等的差异。结果:观察组治疗后痊愈率为22.73%(10/44),总有效率为95.45%(42/44),均显著高于对照组的6.82%(3/44)和81.82%(36/44),差异有统计学意义(P<0.05);治疗后7 d与14 d,观察组NIHSS评分显著低于对照组,GCS评分均显著高于对照组,FIB显著高于对照组,DD及TNF-α值显著低于对照组,差异均有统计学意义(P<0.05)。结论:醒脑静治疗急性CH患者的疗效较常规治疗好,可显著改善患者预后。展开更多
文摘Objective: to study the influence of Chinese medicines for promoting blood circulation to remove blood stasis on fibrinogen (FIB) and D-dimer (DD) in plasma of patients with cerebral thrombosis. Method: 73 inpatients with acute cerebral thrombosis were randomly divided into a control group of 34 cases and a treatment group of 39 cases. The content of FIB and DD in plasma was detected before treatment and on the 7th and 14th days after treatment. Result: FIB content in plasma after treatment was lower than that before treatment in the control group (P<0.01) and more remarkable in the treatment group (P<0.001). There was an obvious difference in DD content before and after treatment in both groups. DD content on the 7th and 14th days after treatment in the treatment group was obviously higher than that in the control group (P<0.01 and P<0.05 respectively). Conclusion: Chinese medicines for promoting blood circulation to remove blood stasis can reduce the FIB content in plasma of patients with cerebral thrombosis, raise the DD content in plasma, cause the peak of DD content appear earlier and obviously improve hypercoagulability of blood in patients with cerebral thrombosis.
文摘目的:观察醒脑静对急性脑出血患者血浆FIB、DD、TNF-α水平的影响。方法:选取88例急性脑出血患者为研究对象,以随机数字表法分成观察组和对照组各44例。对照组给予常规治疗,观察组在对照组的基础上给予醒脑静治疗。比较两组患者治疗前后血浆纤维蛋白原(Fibrinogen,FIB)、D-二聚体(D-Dimer,D-D)、肿瘤坏死因子-α(Tumor Necrosis Factor-α,TNF-α)水平、美国国立卫生研究院卒中量表(National Institute of Health stroke scale,NIHSS)评分、格拉斯哥昏迷(Glasgow Coma Scale,GCS)评分及临床疗效等的差异。结果:观察组治疗后痊愈率为22.73%(10/44),总有效率为95.45%(42/44),均显著高于对照组的6.82%(3/44)和81.82%(36/44),差异有统计学意义(P<0.05);治疗后7 d与14 d,观察组NIHSS评分显著低于对照组,GCS评分均显著高于对照组,FIB显著高于对照组,DD及TNF-α值显著低于对照组,差异均有统计学意义(P<0.05)。结论:醒脑静治疗急性CH患者的疗效较常规治疗好,可显著改善患者预后。
