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Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord 被引量:1
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作者 Emily A.Hibbard Liwen Zhou +5 位作者 Cathy Z.Yang Karthik Venkudusamy Yessenia Montoya Alexa Olivarez George D.Bittner Dale R.Sengelaub 《Neural Regeneration Research》 SCIE CAS 2025年第7期2095-2107,共13页
Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically poor.We used a plasmalemmal fusogen,polyethylene g... Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically poor.We used a plasmalemmal fusogen,polyethylene glycol(PEG),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic nerves.We have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration,and PEG-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor recovery.Furthermore,our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target muscles.In this study,we examined the consequences of PEG-fusion for sensory axons of the sciatic nerve.Young adult male and female rats(Sprague–Dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of PEG.Compound action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury site.The success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days postoperatively.At 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish peroxidase.PEG-fusion repair reestablished axonal continuity.Compared to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal areas.Unexpectedly,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repair.This central reorganization may contribute to the improved behavioral recovery seen after PEG-fusion repair,supporting the use of this novel repair methodology over currently available treatments. 展开更多
关键词 AXOTOMY dorsal horn peripheral nerve injury PLASTICITY polyethylene glycol(peg) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase
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Polyethylene glycol has immunoprotective effects on sciatic allografts, but behavioral recovery and graft tolerance require neurorrhaphy and axonal fusion
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作者 Tyler A.Smith Liwen Zhou +6 位作者 Cameron L.Ghergherehchi Michelle Mikesh Cathy Z.Yang Haley O.Tucker JuliAnne Allgood Jared S.Bushman George D.Bittner 《Neural Regeneration Research》 SCIE CAS 2025年第4期1192-1206,共15页
Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal regeneration.Furthermore,such peripher... Behavioral recovery using(viable)peripheral nerve allografts to repair ablation-type(segmental-loss)peripheral nerve injuries is delayed or poor due to slow and inaccurate axonal regeneration.Furthermore,such peripheral nerve allografts undergo immunological rejection by the host immune system.In contrast,peripheral nerve injuries repaired by polyethylene glycol fusion of peripheral nerve allografts exhibit excellent behavioral recovery within weeks,reduced immune responses,and many axons do not undergo Wallerian degeneration.The relative contribution of neurorrhaphy and polyethylene glycol-fusion of axons versus the effects of polyethylene glycol per se was unknown prior to this study.We hypothesized that polyethylene glycol might have some immune-protective effects,but polyethylene glycol-fusion was necessary to prevent Wallerian degeneration and functional/behavioral recovery.We examined how polyethylene glycol solutions per se affect functional and behavioral recovery and peripheral nerve allograft morphological and immunological responses in the absence of polyethylene glycol-induced axonal fusion.Ablation-type sciatic nerve injuries in outbred Sprague–Dawley rats were repaired according to a modified protocol using the same solutions as polyethylene glycol-fused peripheral nerve allografts,but peripheral nerve allografts were loose-sutured(loose-sutured polyethylene glycol)with an intentional gap of 1–2 mm to prevent fusion by polyethylene glycol of peripheral nerve allograft axons with host axons.Similar to negative control peripheral nerve allografts not treated by polyethylene glycol and in contrast to polyethylene glycol-fused peripheral nerve allografts,animals with loose-sutured polyethylene glycol peripheral nerve allografts exhibited Wallerian degeneration for all axons and myelin degeneration by 7 days postoperatively and did not recover sciatic-mediated behavioral functions by 42 days postoperatively.Other morphological signs of rejection,such as collapsed Schwann cell basal lamina tubes,were absent in polyethylene glycol-fused peripheral nerve allografts but commonly observed in negative control and loose-sutured polyethylene glycol peripheral nerve allografts at 21 days postoperatively.Loose-sutured polyethylene glycol peripheral nerve allografts had more pro-inflammatory and less anti-inflammatory macrophages than negative control peripheral nerve allografts.While T cell counts were similarly high in loose-sutured-polyethylene glycol and negative control peripheral nerve allografts,loose-sutured polyethylene glycol peripheral nerve allografts expressed some cytokines/chemokines important for T cell activation at much lower levels at 14 days postoperatively.MHCI expression was elevated in loose-sutured polyethylene glycol peripheral nerve allografts,but MHCII expression was modestly lower compared to negative control at 21 days postoperatively.We conclude that,while polyethylene glycol per se reduces some immune responses of peripheral nerve allografts,successful polyethylene glycol-fusion repair of some axons is necessary to prevent Wallerian degeneration of those axons and immune rejection of peripheral nerve allografts,and produce recovery of sensory/motor functions and voluntary behaviors.Translation of polyethylene glycol-fusion technologies would produce a paradigm shift from the current clinical practice of waiting days to months to repair ablation peripheral nerve injuries. 展开更多
关键词 allograft rejection AXOTOMY macrophage MYELIN nerve repair polyethylene glycol(peg) sciatic nerve T cell transplantation Wallerian degeneration
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Effect of Free Cells and Additional Supporting Material on Performance of Polyethylene Glycol (PEG)-Pellet Reactor to Treat NH4-N Contaminated Groundwater
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作者 Wilawan Khanitchaidecha Tatsuo Sumino Futaba Kazama 《Journal of Water Resource and Protection》 2011年第1期12-21,共10页
To study the effect of free cells (suspended bacteria) on performance of entrapped bacteria system (i.e. polyethylene glycol (PEG)-pellet reactor) to treat NH4-N contaminated groundwater, two PEG-pellet reactors with ... To study the effect of free cells (suspended bacteria) on performance of entrapped bacteria system (i.e. polyethylene glycol (PEG)-pellet reactor) to treat NH4-N contaminated groundwater, two PEG-pellet reactors with a lot of free cells - Reactor A containing PEG-pellet and Reactor B containing PEG-pellet and supporting material - and the another control reactor without free cells (Reactor C) were set-up. Three reactors were operated under various NH4-N concentrations (40-60 mg/L) and various temperatures (5-25oC). The results show that the free cells effected on the NH4-N removal efficiency significantly. The free cells developed to be a biofilm layer on the pellet surface for Reactor A, the biofilm layer caused the decreasing NH4-N diffusion and incomplete nitrification eventually. On the other hand, most free cells attached to the supporting material for Reactor B. Although the NH4-N could diffuse properly, the free cells consuming acetate caused the added acetate was insufficient for complete denitrification. However, the results suggest that the supporting material could reduce the effect of free cells on the reactor performance at low temperature as indicated by 1) higher efficiency and 2) lower activation energy (Ea) for nitrification and denitrification in Reactor B than Reactor A. 展开更多
关键词 NH4-N removal Nitrification and Denitrification Groundwater Purification polyethylene glycol (peg)-Pellet SUPPORTING MATERIAL Free CELLS
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Effect of Silicon (Si) Application on Phoenix dactylifera L. Growth under Drought Stress Induced by Polyethylene Glycol (PEG) in Vitro
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作者 Ahmed Madi Waheed Al-Mayahi 《American Journal of Plant Sciences》 2016年第13期1711-1728,共18页
This study was carried out to investigate the effects of silicon (Si) 3.6 mM (as calcium silicate) under drought stress induced by polyethylene glycol “PEG” at 15% (MW 8000), in addition to the control treatment on ... This study was carried out to investigate the effects of silicon (Si) 3.6 mM (as calcium silicate) under drought stress induced by polyethylene glycol “PEG” at 15% (MW 8000), in addition to the control treatment on growth and some biochemical constituents of date palm cv. Barhee cultured in vitro. Drought stress (15% PEG) depressed the growth of shoot and decreased protein content and chlorophyll concentration. Addition of 3.6 mM Si could improve the growth of shoot and increase the protein content and leaf chlorophyll concentrations of stressed plants. The inclusion of Si to the PEG containing medium significantly increased the catalase (CAT) and superoxide dismutase (SOD) activity in regenerated shoot, compared to other treatments. As well as drought stress 15% PEG induced significant accumulation of shoots proline, which were decreased by added silicon. Moreover, the results were also supported by the observation that PEG stress-induced decrease the response percentage of root induction and root lengths was reversed by added silicon. Addition of Si obviously significantly increased the wax content in leaves, response percentage of root induction and root lengths of plantlets under drought stress. The results of this study indicate that the application of silicon improved growth attributes, effectively mitigate the adverse effect of drought, and increase tolerance of date palm plants for drought stress during the course of date palm tissue cultures. 展开更多
关键词 Silicon (Si) Drought Stress polyethylene glycol (peg) Tissue Culturing Antioxidant Activity Waxy Layer
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PEG-6000模拟干旱胁迫对不同青稞发芽的影响
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作者 吴拓 白玛曲珍 +2 位作者 刘磊 谢婉 扎西普赤 《西藏农业科技》 2024年第2期16-20,共5页
为了明确聚乙二醇(PEG-6000)模拟干旱胁迫对青稞苗的影响,以9个青稞品种(系)种子为试验材料,研究比较了在5%,10%,15%和20%PEG-6000模拟干旱胁迫和对照处理下(不含PEG-6000)培养8 d青稞发芽率及苗生长生理指标的变化。结果表明,从CK到20%... 为了明确聚乙二醇(PEG-6000)模拟干旱胁迫对青稞苗的影响,以9个青稞品种(系)种子为试验材料,研究比较了在5%,10%,15%和20%PEG-6000模拟干旱胁迫和对照处理下(不含PEG-6000)培养8 d青稞发芽率及苗生长生理指标的变化。结果表明,从CK到20%PEG-6000,各青稞的出苗率降低,发芽时间延长,茎长随着PEG-6000浓度增加而降低,青稞的苗茎鲜重和茎干重随着PEG-6000浓度的增加而减少。随着PEG-6000浓度的增加,各青稞品种生长性降低,PEG-6000浓度的升高使青稞生长受干旱胁迫严重,在不含PEG-6000的培养基中生长最好。 展开更多
关键词 青稞 聚乙二醇(peg-6000) 干旱胁迫
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不同分子质量PEG对水泥基材料性能的影响 被引量:1
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作者 孔德玉 孙浩铨 +3 位作者 王蓉 曾法军 张永军 陈元朋 《新型建筑材料》 2023年第2期74-78,共5页
研究了相对分子质量分别为1000和6000的2种聚乙二醇(分别记为P10和P60)对水泥基材料性能的影响。结果表明:掺P60对水泥砂浆的增黏效果明显优于掺P10。掺P60对水泥砂浆3 d和28 d抗折、抗压强度有明显增强作用,但养护至90 d时,其增强效果... 研究了相对分子质量分别为1000和6000的2种聚乙二醇(分别记为P10和P60)对水泥基材料性能的影响。结果表明:掺P60对水泥砂浆的增黏效果明显优于掺P10。掺P60对水泥砂浆3 d和28 d抗折、抗压强度有明显增强作用,但养护至90 d时,其增强效果已不明显;掺P10则在所有龄期对水泥砂浆均无明显增强效果。掺聚乙二醇(PEG)可一定程度上减小水泥砂浆在6.0mol/L氯化铵溶液中浸泡的强度损失率,但其对砂浆抗溶蚀性能和抗氯离子渗透性能均有不利影响。掺P10对水泥砂浆抗氯离子渗透性能的不利影响明显小于掺P60,其原因是掺P10对硬化水泥石毛细孔和有害孔的影响较小所致。 展开更多
关键词 聚乙二醇(peg) 水泥基材料 力学性能 耐久性 微观结构
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Synthesis and Characterization of Storage Energy Materials Prepared from Nano-crystalline Cellulose/Polyethylene Glycol 被引量:5
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作者 Xiao Ping YUAN En Yong DING 《Chinese Chemical Letters》 SCIE CAS CSCD 2006年第8期1129-1132,共4页
This paper gives a brief report of the synthesis of a new kind of solid-solid phase change materials (SSPCMs), nano-crystalline cellulose/polyethylene glycol (NCC/PEG). These PCMs have very high ability for energy... This paper gives a brief report of the synthesis of a new kind of solid-solid phase change materials (SSPCMs), nano-crystalline cellulose/polyethylene glycol (NCC/PEG). These PCMs have very high ability for energy storage, and their enthalpies reach 103.8 J/g. They are composed of two parts, PEG as functional branches for energy storage, and NCC as skeleton. The flexible polymer PEG was grafted onto the surface of rigid powder of NCC by covalent bonds. The results of DSC, FT-IR were briefly introduced, and some comments were also given. 展开更多
关键词 Nano-crystalline cellulose (NCC) polyethylene glycol peg phase change materials(PCM) energy storage DSC.
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Effects of NaCl and Iso-Osmotic Polyethylene Glycol Stress on Na^+/H^+Antiport Activity of Three Malus species with Different Salt Tolerance 被引量:1
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作者 YANG Hong-bing DONG Chun-hai +2 位作者 XU Xue-feng WANG Yi HAN Zhen-hai 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2014年第6期1276-1283,共8页
Salt stress contains osmotic and ionic stress, while iso-osmotic polyethylene glycol (PEG) has only osmotic stress. This study aimed to compare the different effects on the activity of H+-ATPase, proton pump and Na... Salt stress contains osmotic and ionic stress, while iso-osmotic polyethylene glycol (PEG) has only osmotic stress. This study aimed to compare the different effects on the activity of H+-ATPase, proton pump and Na+/H+antiport in Malus seedlings between osmotic and ionic stress. Species of salt tolerant Malus zumi, middle salt tolerant Malus xiaojinensis and salt sensitive Malus baccata were used as experimental materials. Malus seedlings were treated with NaCl and iso-osmotic PEG stress. The activity of H+-ATPase, proton pump and Na+/H+antiport of plasmolemma and tonoplast in Malus seedlings were obviously increased under salt stress, and those in salt-tolerant species increased more. Under the same NaCl concentration, the activity of H+-ATPase, proton pump and Na+/H+antiport of plasmolemma and tonoplast in salt-tolerant species were all obviously higher than those in salt-sensitive one. Higher Na+/H+antiport activity of plasmolemma and tonoplast in salt-tolerant species could help to extrude and compartmentalize sodium in roots under salt stress. The ascent rate of activity of H+-ATPase, proton pump and Na+/H+antiport in Malus seedlings under the three salt concentration stress was all obviously higher than that under the iso-osmotic PEG stress. It indicated that the sodium ion effect had more stimulation on the activity of H+-ATPase, proton pump and Na+/H+antiport in salt-tolerant species, and salt-tolerant species has higher capability of sodium extrusion and compartmentalization in roots and is therefore more salt tolerant. 展开更多
关键词 MALUS NACL polyethylene glycol peg Na+/H+ antiport activity salt tolerance
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Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury 被引量:3
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作者 Gianfranco Pasut Arnau Panisello +7 位作者 Emma Folch-Puy Alexandre Lopez Carlos Castro-Benítez Maria Calvo Teresa Carbonell Agustín García-Gil RenéAdam Joan Roselló-Catafau 《World Journal of Gastroenterology》 SCIE CAS 2016年第28期6501-6508,共8页
Liver ischemia-reperfusion injury(IRI) is an inherent feature of liver surgery and liver transplantation in which damage to a hypoxic organ(ischemia) is exacerbated following the return of oxygen delivery(reperfusion)... Liver ischemia-reperfusion injury(IRI) is an inherent feature of liver surgery and liver transplantation in which damage to a hypoxic organ(ischemia) is exacerbated following the return of oxygen delivery(reperfusion). IRI is a major cause of primary nonfunction after transplantation and may lead to graft rejection, regardless of immunological considerations. The immediate response involves the disruption of cellular mitochondrial oxidative phosphorylation and the accumulation of metabolic intermediates during the ischemic period, and oxidative stress during blood flow restoration. Moreover, a complex cascade of inflammatory mediators is generated during reperfusion, contributing to the extension of the damage and finally to organ failure. A variety of pharmacological interventions(antioxidants, anticytokines, etc.) have been proposed to alleviate graft injury but their usefulness is limited by the local and specific action of the drugs and by their potential undesirable toxic effects. Polyethylene glycols(PEGs), which are non-toxic water-soluble compounds approved by the FDA, have been widely used as a vehicle or a base in food, cosmetics and pharmaceuticals, and also as adjuvants for ameliorating drug pharmacokinetics. Some PEGs are also currently used as additives in organ preservation solutions prior to transplantation in order to limit the damage associated with cold ischemia reperfusion. More recently, the administration of PEGs of different molecular weights by intravenous injection has emerged as a new therapeutic tool to protect liver grafts from IRI. In this review, we summarize the current knowledge concerning the use of PEGs as a useful target for limiting liver IRI. 展开更多
关键词 Ischemia reperfusion injury polyethylene glycol Liver preconditioning Liver transplantation UW solution IGL-1 solution SCOT solution peg rinse solution Machine perfusion
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Isothermal Crystallization Kinetics of Microencapsulated Polyethylene Glycol Particles 被引量:2
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作者 董知之 张志英 +3 位作者 陈莉 宋正红 王曙光 蒋艾兵 《Journal of Donghua University(English Edition)》 EI CAS 2007年第2期157-160,共4页
The microenapsulated polyethylene glycol (PEG) with different molecular weight by a fluidized coating method has been prepared and the crystallization behaviors of PEG particles in three-dimensional confined vohume ... The microenapsulated polyethylene glycol (PEG) with different molecular weight by a fluidized coating method has been prepared and the crystallization behaviors of PEG particles in three-dimensional confined vohume were investigated by using differential scanning calorimetry (DSC) measurement. The results showed that the width of the crystallization peak of PEG increases and its height gradually diminishes in case that the PEG particles are microencapsulated. Compared with the non-microencapsulated PEG particles, the proportion of the first crystallization peak of microencapsulated PEG particle increases, and that of the second one decreases. The reason for the difference maybe is that the crystallization process of microencapsulated PEG particles is uniform and the crystallization ends when the spherulites touch the wall, thus the opportunity of producing the second crystallization peak was relatively reduced. 展开更多
关键词 MICROENCAPSULATION polyethylene glycol peg CRYSTALLIZATION
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Polymerization of Bisphenol A Epoxy Resin with Polyethylene glycol 被引量:2
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作者 Zhen Zhong YANG De Lu ZHAo Mao XU(Polymer Physics Laboratory, Institute of Chemistry, The Chinese Academy of Sciences, Beijing 100080) 《Chinese Chemical Letters》 SCIE CAS CSCD 1997年第8期725-728,共4页
The catalyst boron trifluoride etherate was used to catalyze the reaction of epoxy resin with polyethylene glycol (PEG), and the effect of the concentration of the catalyst on the reaction is studied. It is shown that... The catalyst boron trifluoride etherate was used to catalyze the reaction of epoxy resin with polyethylene glycol (PEG), and the effect of the concentration of the catalyst on the reaction is studied. It is shown that there exist two competitive reactions : I, self polymerization of epoxy resin via chain growth and II, copolymerization of epoxy resin with PEG via step growth. At high concentration of the catalyst reaction I dominates and reaction II is negligible. On the contrary, at low concentration of the catalyst, reaction II dominates and block copolymers are formed In the intermediate case, the two reactions are comparable with the result that a gel structure is obtained. 展开更多
关键词 peg Polymerization of Bisphenol A Epoxy Resin with polyethylene glycol
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赤霉素处理对PEG模拟干旱条件下茄子种子萌发的影响 被引量:2
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作者 张天宇 李楚怡 +8 位作者 张芮豪 姜守阳 张祥 蒋舒蕊 李平平 王梓然 赵凯 邓明华 吕俊恒 《长江蔬菜》 2023年第4期52-56,共5页
为了研究赤霉素浸种处理对PEG模拟干旱条件下茄子种子萌发的影响,本研究以3个品种茄子种子为试验材料,采用4种浓度(0、100、300、500 mg/L)的赤霉素浸种24 h后置于20%聚乙二醇(PEG)胁迫处理下进行种子发芽试验。试验结果表明,300 mg/L... 为了研究赤霉素浸种处理对PEG模拟干旱条件下茄子种子萌发的影响,本研究以3个品种茄子种子为试验材料,采用4种浓度(0、100、300、500 mg/L)的赤霉素浸种24 h后置于20%聚乙二醇(PEG)胁迫处理下进行种子发芽试验。试验结果表明,300 mg/L赤霉素浸种处理明显提高了3个品种茄子种子的发芽势、发芽率,并且降低了芽抑制率及根抑制率,能明显缓解干旱对茄子种子发芽率、幼苗生长的抑制作用。促进幼苗生长的最适赤霉素浓度为300 mg/L。 展开更多
关键词 茄子种子 赤霉素 聚乙二醇(peg) 种子萌发
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Electrochemical oxidation of polyethylene glycol in electroplating solution using paraffin composite copper hexacyanoferrate modified (PCCHM) anode
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作者 Rajesh S. Bejankiwar Abir Basu Max Cementi 《Journal of Environmental Sciences》 SCIE EI CAS CSCD 2004年第5期851-855,共5页
Electrochemical oxidation of polyethylene glycol(PEG) in an acidic(pH 0.18 to 0.42) and high ionic strength electroplating solution was investigated. The electroplating solution is a major source of wastewater in the ... Electrochemical oxidation of polyethylene glycol(PEG) in an acidic(pH 0.18 to 0.42) and high ionic strength electroplating solution was investigated. The electroplating solution is a major source of wastewater in the printing wiring board industry. A paraffin composite copper hexacyanoferrate modified(PCCHM) electrode was used as the anode and a bare graphite electrode was used as the cathode. The changes in PEG and total organic carbon(TOC) concentrations during the course of the reaction were monitored. The efficiency of the PCCHM anode was compared with bare graphite anode and it was found that the former showed significant electrocatalytic property for PEG and TOC removal. Chlorides present in the solution were found to contribute significantly in the overall organic removal process. Short chain organic compounds like acetic acid, oxalic acid, formic acid and ethylene glycol formed during electrolysis were identified by HPLC method. Anode surface area and applied current density were found to influence the electro-oxidation process, in which the former was found to be dominating. Investigations of the kinetics for the present electrochemical reaction suggested that the two stage first-order kinetic model provides a much better representation of the overall mechanism of the process if compared to the generalized kinetic model. 展开更多
关键词 polyethylene glycol(peg) paraffin composite copper hexacyanoferrate modified(PCCHM) electrode electroplating solution two stage first-order kinetic model generalized kinetic model
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聚乙二醇基(PEG)水凝胶包埋漆酶研究
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作者 樊翔泽 凡怡茹 +3 位作者 刘伟 周丹阳 应宇宣 朱金花 《化学研究》 CAS 2023年第3期259-266,共8页
漆酶(Laccase)在有机污染物降解以及废水处理等环境治理领域有着杰出的作用,但在极端温度和pH下容易失活,限制了其应用。因此,设计具有较好保护作用的漆酶固定化载体,以扩大其在环境污染防治领域的应用具有重要的研究意义。采用紫外光... 漆酶(Laccase)在有机污染物降解以及废水处理等环境治理领域有着杰出的作用,但在极端温度和pH下容易失活,限制了其应用。因此,设计具有较好保护作用的漆酶固定化载体,以扩大其在环境污染防治领域的应用具有重要的研究意义。采用紫外光照聚合法将漆酶固定在水凝胶(PEG)上,然后与戊二醛(GA)交联,得到了固定化漆酶水凝胶微球Lac/particles。以2,2′-联氮双(3-乙基苯并噻唑啉-6-磺酸)(ABTS)为底物,对包埋后的漆酶的活性进行了考察。研究结果表明,在凝胶的保护下,Lac的pH耐受性、温度耐受性以及储存稳定性等方面均比游离漆酶有着不同程度的增强。 展开更多
关键词 聚乙二醇基(peg)水凝胶 漆酶 固定化
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Poly Ethylene Glycols (PEG) and Micelles as Efficient Catalysts for the Oxidation of Xanthine Derivatives under Conventional and Non-Conventional Conditions
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作者 Somannagari Shylaja Kola Ramesh +2 位作者 Pochampally Giridhar Reddy Kamatala Chinna Rajanna Pondichery Kuppuswamy Saiprakash 《International Journal of Organic Chemistry》 2011年第4期148-157,共10页
Oxidation of Xanthine alkaloid have been studied with various one and two electron oxidizing agents using PEGs and micelle forming surfactants. The reaction is too sluggish in solution phase, but moderately fast in pr... Oxidation of Xanthine alkaloid have been studied with various one and two electron oxidizing agents using PEGs and micelle forming surfactants. The reaction is too sluggish in solution phase, but moderately fast in presence of PEGs and micelles. However, the reactions are dramatically enhanced under microwave irradiations. Present protocol has several advantages, such as solvent-free conditions, during work-up, fast reaction times, high yields, eco-friendly operational and experimental simplicity, readily available additives as catalysts. 展开更多
关键词 OXIDATION XANTHINE Alkaloids One And Two Electron Oxidizing Agents POLY Ethylene glycolS (peg) Micelle Forming Surfactants Catalysts Microwave Irradiations
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Studies on the Absorption of NO_2 by Polyethylene Glycol and the Oxidizing Properties of the Resulting Absorbent Product
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作者 Xue Sen FAN Qing Zhi ZHANG +1 位作者 Xin Ying ZRANG Sen Song ZHANG (Department of Chemistry, Henan Normal University, Xinxiang, 453002) 《Chinese Chemical Letters》 SCIE CAS CSCD 1997年第9期747-748,共2页
PEG (Polyethylene glycol average molecular weight 300) is used as absorbent of NO2. The absorption efficiency is found to reach up to 97%. The absorbing product, PEG NO2, can be used to cleave benzyl ethers mildly a... PEG (Polyethylene glycol average molecular weight 300) is used as absorbent of NO2. The absorption efficiency is found to reach up to 97%. The absorbing product, PEG NO2, can be used to cleave benzyl ethers mildly and selectively to benzaldehyde and corresponding fatty alcohols, showing that PEG is a valuable oxidizing agent of benzyl ethers. As a carrier of NO2.PEG can be recovered and utilized repeatedly after the oxidation. 展开更多
关键词 NO Studies on the Absorption of NO2 by polyethylene glycol and the Oxidizing Properties of the Resulting Absorbent Product peg
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芭纱木-PEG储能建筑材料的制备与性能研究 被引量:1
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作者 魏彬 李璐 《塑料助剂》 CAS 2023年第1期16-19,共4页
为了使芭纱木建材具有一定的室内温度调节功能,形成具有储放热性能的相变储能材料,本次研究对芭纱木原木实施细胞壁去除处理,进而取得木质基多孔封装载体。在此基础上通过真空浸渍的方法将聚乙二醇(PEG)嵌入芭纱木中,形成芭纱木-PEG木... 为了使芭纱木建材具有一定的室内温度调节功能,形成具有储放热性能的相变储能材料,本次研究对芭纱木原木实施细胞壁去除处理,进而取得木质基多孔封装载体。在此基础上通过真空浸渍的方法将聚乙二醇(PEG)嵌入芭纱木中,形成芭纱木-PEG木质基相变储能复合材料。采用红外温度检测仪、差示扫描量热测试、氙灯耐候试验箱等仪器对复合材料的储放热性能及其在循环储放热过程中所体现出来的化学稳定性进行测试。经实验研究发现,本次研究所制备的芭纱木-PEG储能建筑材料储放热性能优良,具有可靠的化学稳定性和热稳定性,具有一定的应用价值。 展开更多
关键词 聚乙二醇(peg) 芭纱木 储能建筑材料 性能分析
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PROPERTIES AND IMMUNOACTIVITY OF MODIFIED IMMUNOGLOBULING BY METHOXYPOLYETHYLENE GLYCOL
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作者 Shi Jianying Tong Mingrong +2 位作者 Chen Jiatong shen Shigang Yu Yaoting,Institute for Molecular Biology Nankai University. Tianjin. P. R. China 《Chinese Journal of Biomedical Engineering(English Edition)》 1993年第1期10-15,共6页
Methoxypolyethylene glycols of 5000 dalton(PEG) have been attached covalentlyto human serum immunoglobulin G using 2,4,6-trichloro-s-triazine as coupling agent. The modi-fied IgG showed substantial changes in properti... Methoxypolyethylene glycols of 5000 dalton(PEG) have been attached covalentlyto human serum immunoglobulin G using 2,4,6-trichloro-s-triazine as coupling agent. The modi-fied IgG showed substantial changes in properties as compared with the unmodified IgG. The mod-ified IgG showed increase in molecular weight, increase of tolerance to temperature and PH, de-crease of immunogenicity and retaining most of its immunoactivity. The CD spectra showed no ap-parent changes in its main structure. IgG with 50. 3% of its amino groups modified by PEG had its immunogenicity completely re-moved ,while maintaining 53.7% of its immunoactivity. 展开更多
关键词 IMMUNOGLOBULIN G(IgG) Methoxypolyethylene glycol(peg) Chemical MODIFICATION
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The Modeling and Study of Depletion Interaction at Mixture of C_(12)E_(5) Microemulsion with Polyethylene Glycol Polymer
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作者 Soheil Sharifi Masoud Amirkhani Othmar Marti 《Soft Nanoscience Letters》 2012年第4期71-76,共6页
he photon correlation spectroscopy and small-angle X-ray scattering is used for study the mixture of C12E5 microemulsion with PEG in order to determine structure and dynamic of the system. Photon correlation spectrosc... he photon correlation spectroscopy and small-angle X-ray scattering is used for study the mixture of C12E5 microemulsion with PEG in order to determine structure and dynamic of the system. Photon correlation spectroscopy experiment showed an exponential relaxation for pure C12E5 microemulsion that come from Brownian motion of oil nano-droplets in water. The shape of the relaxation changed with increasing of PEG concentration in the C12E5 microemulsion, (relaxation becomes non-exponential with the increase of PEG), which demonstrates an increase of cooperatively in the C12E5 microemulsion. The SAXS experiment was used to study the structure of the system, and a model consists of a mixture of core-shell spheres with an Asakura-Oosawa interaction was applied to analyze data. 展开更多
关键词 Nano-Droplet SAXS Light Scattering polyethyl glycol
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蜂蜜在住院患者结肠镜检查前肠道准备中的应用
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作者 潘杰 葛少莉 +5 位作者 王瑶 林中华 林玉娇 毛宁宁 韩荣荣 隋牮箐 《中国内镜杂志》 2024年第9期33-40,共8页
目的探讨蜂蜜在住院患者行结肠镜检查前肠道准备中的临床效果。方法选择2022年4月-2022年7月于该院消化科住院拟行结肠镜检查前肠道准备的患者87例,采用便利抽样法分为对照组(n=43)和观察组(n=44)。对照组采用常规方案服用复方聚乙二醇(... 目的探讨蜂蜜在住院患者行结肠镜检查前肠道准备中的临床效果。方法选择2022年4月-2022年7月于该院消化科住院拟行结肠镜检查前肠道准备的患者87例,采用便利抽样法分为对照组(n=43)和观察组(n=44)。对照组采用常规方案服用复方聚乙二醇(PEG)电解质散(和爽)进行肠道准备,观察组在和爽溶液中添加20 mL蜂蜜进行肠道准备。比较两组患者肠道清洁度、和爽口感、患者不良反应、患者满意度和再次肠道准备意愿。结果两组患者肠道清洁度比较,差异无统计学意义(P>0.05)。观察组恶心、腹胀、低血糖和肛门刺激征发生率低于对照组,严重程度轻于对照组,差异均有统计学意义(P<0.05)。观察组和爽口感优于对照组,患者满意度和再次肠道准备意愿高于对照组,差异均有统计学意义(P<0.05)。结论蜂蜜可以改善和爽的口感,降低口服和爽不良反应发生率及严重程度,提高患者满意度和再次肠道准备意愿。 展开更多
关键词 蜂蜜 复方聚乙二醇(peg)电解质散 结肠镜检查 肠道准备 口感
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