A new seco-anthraquinone,crispuside A(1),and three new 3,4-dihydronaphthalen-1(2H)-ones,napthalenones A-C(2-4),were isolated from the roots of Rumex crispus L.,along with 10 known anthraquinones(6-14)and naph-thalenon...A new seco-anthraquinone,crispuside A(1),and three new 3,4-dihydronaphthalen-1(2H)-ones,napthalenones A-C(2-4),were isolated from the roots of Rumex crispus L.,along with 10 known anthraquinones(6-14)and naph-thalenone(5).Their structures were fully determined by extensive spectroscopic analyses,including ECD,and X-ray crystallography in case of compound 5,whose absolute configuration was determined for the first time.The isolates 1,6-14 were evaluated for their anti-inflammatory and anti-fungal activity against three skin fungi,e.g.,Epidermophyton floccosum,Trichophyton rubrum,and Microsporum gypseum.Most of the isolates showed weak anti-fungal and anti-inflammatory activity.Only compound 9 exhibited obvious anti-fungal activity against E.floccosum(MIC_(50)=2.467±0.03μM)and M.gypseum(MIC_(50)=4.673±0.077μM),while the MIC_(50)values of the positive control terbinafine were 1.287±0.012 and 0.077±0.00258μM,respectively.The results indicated that simple emodin type anthraquinone is more potential against skin fungi than its oxyglucosyl,C-glucosyl and glycosylated seco analogues.展开更多
In order to investigate the effect of plant density ofPotamogeton crispus L. on the remediation of sedi- ments contaminated by polycyclic aromatic hydrocarbons, a 54-day experiment with four plant densities （642, 1 6...In order to investigate the effect of plant density ofPotamogeton crispus L. on the remediation of sedi- ments contaminated by polycyclic aromatic hydrocarbons, a 54-day experiment with four plant densities （642, 1 604, 2 567 and 3 530 plants/m^2） was conducted. The results showed higher plant density with slower plant growth rate. Surface area per plant was the most sensitive root parameter to plant density. At the end of the 54-day experi- ment, planting P. crispus enhanced the dissipation ratios of phenanthrene and pyrene in sediments by 6.5%-26,2% and 0.95%-13.6%, respectively. The dissipation increment increased with increasing plant density. Plant uptake accounted for only a small portion of the dissipation increments. Furthermore, P. crispus could evidently improve sediment redox potentials, and strong positive correlations between root surface area and the redox potential as well as between the redox potentials and the dissipation ratios of phenanthrene and pyrene were obtained, indicating that the oxygen released by the roots ofP. crispus might be the main mechanism by which P. crispus enhanced the dis- sipation of PAHs in sediments.展开更多
基金supported by Ministry of Science and Technology of the People’s Republic of China,2021YFE0103600.
文摘A new seco-anthraquinone,crispuside A(1),and three new 3,4-dihydronaphthalen-1(2H)-ones,napthalenones A-C(2-4),were isolated from the roots of Rumex crispus L.,along with 10 known anthraquinones(6-14)and naph-thalenone(5).Their structures were fully determined by extensive spectroscopic analyses,including ECD,and X-ray crystallography in case of compound 5,whose absolute configuration was determined for the first time.The isolates 1,6-14 were evaluated for their anti-inflammatory and anti-fungal activity against three skin fungi,e.g.,Epidermophyton floccosum,Trichophyton rubrum,and Microsporum gypseum.Most of the isolates showed weak anti-fungal and anti-inflammatory activity.Only compound 9 exhibited obvious anti-fungal activity against E.floccosum(MIC_(50)=2.467±0.03μM)and M.gypseum(MIC_(50)=4.673±0.077μM),while the MIC_(50)values of the positive control terbinafine were 1.287±0.012 and 0.077±0.00258μM,respectively.The results indicated that simple emodin type anthraquinone is more potential against skin fungi than its oxyglucosyl,C-glucosyl and glycosylated seco analogues.
基金Supported by the National Natural Science Foundation of China(No.21377091)
文摘In order to investigate the effect of plant density ofPotamogeton crispus L. on the remediation of sedi- ments contaminated by polycyclic aromatic hydrocarbons, a 54-day experiment with four plant densities （642, 1 604, 2 567 and 3 530 plants/m^2） was conducted. The results showed higher plant density with slower plant growth rate. Surface area per plant was the most sensitive root parameter to plant density. At the end of the 54-day experi- ment, planting P. crispus enhanced the dissipation ratios of phenanthrene and pyrene in sediments by 6.5%-26,2% and 0.95%-13.6%, respectively. The dissipation increment increased with increasing plant density. Plant uptake accounted for only a small portion of the dissipation increments. Furthermore, P. crispus could evidently improve sediment redox potentials, and strong positive correlations between root surface area and the redox potential as well as between the redox potentials and the dissipation ratios of phenanthrene and pyrene were obtained, indicating that the oxygen released by the roots ofP. crispus might be the main mechanism by which P. crispus enhanced the dis- sipation of PAHs in sediments.
