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Assessing recent recurrence after hepatectomy for hepatitis Brelated hepatocellular carcinoma by a predictive model based on sarcopenia
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作者 Hong Peng Si-Yi Lei +9 位作者 Wei Fan Yu Dai Yi Zhang Gen Chen Ting-Ting Xiong Tian-Zhao Liu Yue Huang Xiao-Feng Wang Jin-Hui Xu Xin-Hua Luo 《World Journal of Gastroenterology》 SCIE CAS 2024年第12期1727-1738,共12页
BACKGROUND Sarcopenia may be associated with hepatocellular carcinoma(HCC)following hepatectomy.But traditional single clinical variables are still insufficient to predict recurrence.We still lack effective prediction... BACKGROUND Sarcopenia may be associated with hepatocellular carcinoma(HCC)following hepatectomy.But traditional single clinical variables are still insufficient to predict recurrence.We still lack effective prediction models for recent recurrence(time to recurrence<2 years)after hepatectomy for HCC.AIM To establish an interventable prediction model to estimate recurrence-free survival(RFS)after hepatectomy for HCC based on sarcopenia.METHODS We retrospectively analyzed 283 hepatitis B-related HCC patients who underwent curative hepatectomy for the first time,and the skeletal muscle index at the third lumbar spine was measured by preoperative computed tomography.94 of these patients were enrolled for external validation.Cox multivariate analysis was per-formed to identify the risk factors of postoperative recurrence in training cohort.A nomogram model was developed to predict the RFS of HCC patients,and its predictive performance was validated.The predictive efficacy of this model was evaluated using the receiver operating characteristic curve.RESULTS Multivariate analysis showed that sarcopenia[Hazard ratio(HR)=1.767,95%CI:1.166-2.678,P<0.05],alpha-fetoprotein≥40 ng/mL(HR=1.984,95%CI:1.307-3.011,P<0.05),the maximum diameter of tumor>5 cm(HR=2.222,95%CI:1.285-3.842,P<0.05),and hepatitis B virus DNA level≥2000 IU/mL(HR=2.1,95%CI:1.407-3.135,P<0.05)were independent risk factors associated with postoperative recurrence of HCC.Based on the sarcopenia to assess the RFS model of hepatectomy with hepatitis B-related liver cancer disease(SAMD)was established combined with other the above risk factors.The area under the curve of the SAMD model was 0.782(95%CI:0.705-0.858)in the training cohort(sensitivity 81%,specificity 63%)and 0.773(95%CI:0.707-0.838)in the validation cohort.Besides,a SAMD score≥110 was better to distinguish the high-risk group of postoperative recurrence of HCC.CONCLUSION Sarcopenia is associated with recent recurrence after hepatectomy for hepatitis B-related HCC.A nutritional status-based prediction model is first established for postoperative recurrence of hepatitis B-related HCC,which is superior to other models and contributes to prognosis prediction. 展开更多
关键词 ALPHA-FETOPROTEIN Hepatitis B virus HEPATECTOMY Hepatocellular carcinoma NOMOGRAM predictive models RECURRENCE Recurrence-free survival Risk factors SARCOPENIA
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Autonomous Vehicle Platoons In Urban Road Networks:A Joint Distributed Reinforcement Learning and Model Predictive Control Approach
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作者 Luigi D’Alfonso Francesco Giannini +3 位作者 Giuseppe Franzè Giuseppe Fedele Francesco Pupo Giancarlo Fortino 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第1期141-156,共16页
In this paper, platoons of autonomous vehicles operating in urban road networks are considered. From a methodological point of view, the problem of interest consists of formally characterizing vehicle state trajectory... In this paper, platoons of autonomous vehicles operating in urban road networks are considered. From a methodological point of view, the problem of interest consists of formally characterizing vehicle state trajectory tubes by means of routing decisions complying with traffic congestion criteria. To this end, a novel distributed control architecture is conceived by taking advantage of two methodologies: deep reinforcement learning and model predictive control. On one hand, the routing decisions are obtained by using a distributed reinforcement learning algorithm that exploits available traffic data at each road junction. On the other hand, a bank of model predictive controllers is in charge of computing the more adequate control action for each involved vehicle. Such tasks are here combined into a single framework:the deep reinforcement learning output(action) is translated into a set-point to be tracked by the model predictive controller;conversely, the current vehicle position, resulting from the application of the control move, is exploited by the deep reinforcement learning unit for improving its reliability. The main novelty of the proposed solution lies in its hybrid nature: on one hand it fully exploits deep reinforcement learning capabilities for decisionmaking purposes;on the other hand, time-varying hard constraints are always satisfied during the dynamical platoon evolution imposed by the computed routing decisions. To efficiently evaluate the performance of the proposed control architecture, a co-design procedure, involving the SUMO and MATLAB platforms, is implemented so that complex operating environments can be used, and the information coming from road maps(links,junctions, obstacles, semaphores, etc.) and vehicle state trajectories can be shared and exchanged. Finally by considering as operating scenario a real entire city block and a platoon of eleven vehicles described by double-integrator models, several simulations have been performed with the aim to put in light the main f eatures of the proposed approach. Moreover, it is important to underline that in different operating scenarios the proposed reinforcement learning scheme is capable of significantly reducing traffic congestion phenomena when compared with well-reputed competitors. 展开更多
关键词 Distributed model predictive control distributed reinforcement learning routing decisions urban road networks
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A Novel Predictive Model for Edge Computing Resource Scheduling Based on Deep Neural Network
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作者 Ming Gao Weiwei Cai +3 位作者 Yizhang Jiang Wenjun Hu Jian Yao Pengjiang Qian 《Computer Modeling in Engineering & Sciences》 SCIE EI 2024年第4期259-277,共19页
Currently,applications accessing remote computing resources through cloud data centers is the main mode of operation,but this mode of operation greatly increases communication latency and reduces overall quality of se... Currently,applications accessing remote computing resources through cloud data centers is the main mode of operation,but this mode of operation greatly increases communication latency and reduces overall quality of service(QoS)and quality of experience(QoE).Edge computing technology extends cloud service functionality to the edge of the mobile network,closer to the task execution end,and can effectivelymitigate the communication latency problem.However,the massive and heterogeneous nature of servers in edge computing systems brings new challenges to task scheduling and resource management,and the booming development of artificial neural networks provides us withmore powerfulmethods to alleviate this limitation.Therefore,in this paper,we proposed a time series forecasting model incorporating Conv1D,LSTM and GRU for edge computing device resource scheduling,trained and tested the forecasting model using a small self-built dataset,and achieved competitive experimental results. 展开更多
关键词 Edge computing resource scheduling predictive models
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Hybrid Dynamic Variables-Dependent Event-Triggered Fuzzy Model Predictive Control
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作者 Xiongbo Wan Chaoling Zhang +2 位作者 Fan Wei Chuan-Ke Zhang Min Wu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第3期723-733,共11页
This article focuses on dynamic event-triggered mechanism(DETM)-based model predictive control(MPC) for T-S fuzzy systems.A hybrid dynamic variables-dependent DETM is carefully devised,which includes a multiplicative ... This article focuses on dynamic event-triggered mechanism(DETM)-based model predictive control(MPC) for T-S fuzzy systems.A hybrid dynamic variables-dependent DETM is carefully devised,which includes a multiplicative dynamic variable and an additive dynamic variable.The addressed DETM-based fuzzy MPC issue is described as a “min-max” optimization problem(OP).To facilitate the co-design of the MPC controller and the weighting matrix of the DETM,an auxiliary OP is proposed based on a new Lyapunov function and a new robust positive invariant(RPI) set that contain the membership functions and the hybrid dynamic variables.A dynamic event-triggered fuzzy MPC algorithm is developed accordingly,whose recursive feasibility is analysed by employing the RPI set.With the designed controller,the involved fuzzy system is ensured to be asymptotically stable.Two examples show that the new DETM and DETM-based MPC algorithm have the advantages of reducing resource consumption while yielding the anticipated performance. 展开更多
关键词 Dynamic event-triggered mechanism(DETM) hybrid dynamic variables model predictive control(MPC) robust positive invariant(RPI)set T-S fuzzy systems
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Prognostic and predictive role of immune microenvironment in colorectal cancer
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作者 Olesya Kuznetsova Mikhail Fedyanin +8 位作者 Larisa Zavalishina Larisa Moskvina Olga Kuznetsova Alexandra Lebedeva Alexey Tryakin Galina Kireeva Gleb Borshchev Sergei Tjulandin Ekaterina Ignatova 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第3期643-652,共10页
Colorectal cancer(CRC)represents a molecularly heterogeneous disease and one of the most frequent causes of cancer-related death worldwide.The traditional classification of CRC is based on pathomorphological and molec... Colorectal cancer(CRC)represents a molecularly heterogeneous disease and one of the most frequent causes of cancer-related death worldwide.The traditional classification of CRC is based on pathomorphological and molecular character-istics of tumor cells(mucinous,ring-cell carcinomas,etc.),analysis of mechanisms of carcinogenesis involved(chromosomal instability,microsatellite instability,CpG island methylator phenotype)and mutational statuses of commonly altered genes(KRAS,NRAS,BRAF,APC,etc.),as well as expression signatures(CMS 1-4).It is also suggested that the tumor microenvironment is a key player in tumor progression and metastasis in CRC.According to the latest data,the immune microenvironment can also be predictive of the response to immune checkpoint inhibitors.In this review,we highlight how the immune environment influences CRC prognosis and sensitivity to systemic therapy. 展开更多
关键词 Immunoscore Immune microenvironment Colorectal cancer Gastrointestinal cancers predictive biomarkers Digital pathology
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Clinical nursing value of predictive nursing in reducing complications of pregnant women undergoing short-term massive blood transfusion during cesarean section
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作者 Li Cheng Li-Ping Li +2 位作者 Yuan-Yuan Zhang Fang Deng Ting-Ting Lan 《World Journal of Clinical Cases》 SCIE 2024年第1期51-58,共8页
BACKGROUND Cesarean hemorrhage is one of the serious complications,and short-term massive blood transfusion can easily cause postoperative infection and physical stress response.However,predictive nursing intervention... BACKGROUND Cesarean hemorrhage is one of the serious complications,and short-term massive blood transfusion can easily cause postoperative infection and physical stress response.However,predictive nursing intervention has important clinical significance for it.AIM To explore the effect of predictive nursing intervention on the stress response and complications of women undergoing short-term mass blood transfusion during cesarean section(CS).METHODS A clinical medical record of 100 pregnant women undergoing rapid mass blood transfusion during sections from June 2019 to June 2021.According to the different nursing methods,patients divided into control group(n=50)and observation group(n=50).Among them,the control group implemented routine nursing,and the observation group implemented predictive nursing intervention based on the control group.Moreover,compared the differences in stress res-ponse,complications,and pain scores before and after the nursing of pregnant women undergoing rapid mass blood transfusion during CS.RESULTS The anxiety and depression scores of pregnant women in the two groups were significantly improved after nursing,and the psychological stress response of the observation group was significantly lower than that of the control group(P<0.05).The heart rate and mean arterial pressure(MAP)of the observation group during delivery were lower than those of the control group,and the MAP at the end of delivery was lower than that of the control group(P<0.05).Moreover,different pain scores improved significantly in both groups,with the observation group considerably less than the control group(P<0.05).After nursing,complications such as skin rash,urinary retention,chills,diarrhea,and anaphylactic shock in the observation group were 18%,which significantly higher than in the control group(4%)(P<0.05).CONCLUSION Predictive nursing intervention can effectively relieve the pain,reduce the incidence of complications,improve mood and stress response,and serve as a reference value for the nursing of women undergoing rapid mass transfusion during CS. 展开更多
关键词 predictive care Rapid mass blood transfusion Cesarean section Stress response COMPLICATIONS
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Predictive modeling for postoperative delirium in elderly patients with abdominal malignancies using synthetic minority oversampling technique
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作者 Wen-Jing Hu Gang Bai +6 位作者 Yan Wang Dong-Mei Hong Jin-Hua Jiang Jia-Xun Li Yin Hua Xin-Yu Wang Ying Chen 《World Journal of Gastrointestinal Oncology》 SCIE 2024年第4期1227-1235,共9页
BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling techn... BACKGROUND Postoperative delirium,particularly prevalent in elderly patients after abdominal cancer surgery,presents significant challenges in clinical management.AIM To develop a synthetic minority oversampling technique(SMOTE)-based model for predicting postoperative delirium in elderly abdominal cancer patients.METHODS In this retrospective cohort study,we analyzed data from 611 elderly patients who underwent abdominal malignant tumor surgery at our hospital between September 2020 and October 2022.The incidence of postoperative delirium was recorded for 7 d post-surgery.Patients were divided into delirium and non-delirium groups based on the occurrence of postoperative delirium or not.A multivariate logistic regression model was used to identify risk factors and develop a predictive model for postoperative delirium.The SMOTE technique was applied to enhance the model by oversampling the delirium cases.The model’s predictive accuracy was then validated.RESULTS In our study involving 611 elderly patients with abdominal malignant tumors,multivariate logistic regression analysis identified significant risk factors for postoperative delirium.These included the Charlson comorbidity index,American Society of Anesthesiologists classification,history of cerebrovascular disease,surgical duration,perioperative blood transfusion,and postoperative pain score.The incidence rate of postoperative delirium in our study was 22.91%.The original predictive model(P1)exhibited an area under the receiver operating characteristic curve of 0.862.In comparison,the SMOTE-based logistic early warning model(P2),which utilized the SMOTE oversampling algorithm,showed a slightly lower but comparable area under the curve of 0.856,suggesting no significant difference in performance between the two predictive approaches.CONCLUSION This study confirms that the SMOTE-enhanced predictive model for postoperative delirium in elderly abdominal tumor patients shows performance equivalent to that of traditional methods,effectively addressing data imbalance. 展开更多
关键词 Elderly patients Abdominal cancer Postoperative delirium Synthetic minority oversampling technique predictive modeling Surgical outcomes
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Multi-Time Scale Operation and Simulation Strategy of the Park Based on Model Predictive Control
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作者 Jun Zhao Chaoying Yang +1 位作者 Ran Li Jinge Song 《Energy Engineering》 EI 2024年第3期747-767,共21页
Due to the impact of source-load prediction power errors and uncertainties,the actual operation of the park will have a wide range of fluctuations compared with the expected state,resulting in its inability to achieve... Due to the impact of source-load prediction power errors and uncertainties,the actual operation of the park will have a wide range of fluctuations compared with the expected state,resulting in its inability to achieve the expected economy.This paper constructs an operating simulation model of the park power grid operation considering demand response and proposes a multi-time scale operating simulation method that combines day-ahead optimization and model predictive control(MPC).In the day-ahead stage,an operating simulation plan that comprehensively considers the user’s side comfort and operating costs is proposed with a long-term time scale of 15 min.In order to cope with power fluctuations of photovoltaic,wind turbine and conventional load,MPC is used to track and roll correct the day-ahead operating simulation plan in the intra-day stage to meet the actual operating operation status of the park.Finally,the validity and economy of the operating simulation strategy are verified through the analysis of arithmetic examples. 展开更多
关键词 Demand response model predictive control multiple time scales operating simulation
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Disturbance rejection tube model predictive levitation control of maglev trains
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作者 Yirui Han Xiuming Yao Yu Yang 《High-Speed Railway》 2024年第1期57-63,共7页
Magnetic levitation control technology plays a significant role in maglev trains.Designing a controller for the levitation system is challenging due to the strong nonlinearity,open-loop instability,and the need for fa... Magnetic levitation control technology plays a significant role in maglev trains.Designing a controller for the levitation system is challenging due to the strong nonlinearity,open-loop instability,and the need for fast response and security.In this paper,we propose a Disturbance-Observe-based Tube Model Predictive Levitation Control(DO-TMPLC)scheme combined with a feedback linearization strategy for the levitation system.The proposed strategy incorporates state constraints and control input constraints,i.e.,the air gap,the vertical velocity,and the current applied to the coil.A feedback linearization strategy is used to cancel the nonlinearity of the tracking error system.Then,a disturbance observer is implemented to actively compensate for disturbances while a TMPLC controller is employed to alleviate the remaining disturbances.Furthermore,we analyze the recursive feasibility and input-to-state stability of the closed-loop system.The simulation results indicate the efficacy of the proposed control strategy. 展开更多
关键词 Maglev trains Levitation system Constrained control Disturbance observer Model predictive control
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Game Theory Based Model for Predictive Analytics Using Distributed Position Function
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作者 Mirhossein Mousavi Karimi Shahram Rahimi 《International Journal of Intelligence Science》 2024年第1期22-47,共26页
This paper presents a game theory-based method for predicting the outcomes of negotiation and group decision-making problems. We propose an extension to the BDM model to address problems where actors’ positions are d... This paper presents a game theory-based method for predicting the outcomes of negotiation and group decision-making problems. We propose an extension to the BDM model to address problems where actors’ positions are distributed over a position spectrum. We generalize the concept of position in the model to incorporate continuous positions for the actors, enabling them to have more flexibility in defining their targets. We explore different possible functions to study the role of the position function and discuss appropriate distance measures for computing the distance between the positions of actors. To validate the proposed extension, we demonstrate the trustworthiness of our model’s performance and interpretation by replicating the results based on data used in earlier studies. 展开更多
关键词 Distributed Position Function Game Theory Group Decision Making predictive Analytics
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Model Predictive Control for Cascaded H-Bridge PV Inverter with Capacitor Voltage Balance
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作者 Xinwei Wei Wanyu Tao +4 位作者 Xunbo Fu Xiufeng Hua Zhi Zhang Xiaodan Zhao Chen Qin 《Journal of Electronic Research and Application》 2024年第2期79-85,共7页
We designed an improved direct-current capacitor voltage balancing control model predictive control(MPC)for single-phase cascaded H-bridge multilevel photovoltaic(PV)inverters.Compared with conventional voltage balanc... We designed an improved direct-current capacitor voltage balancing control model predictive control(MPC)for single-phase cascaded H-bridge multilevel photovoltaic(PV)inverters.Compared with conventional voltage balanc-ing control methods,the method proposed could make the PV strings of each submodule operate at their maximum power point by independent capacitor voltage control.Besides,the predicted and reference value of the grid-connected current was obtained according to the maximum power output of the maximum power point tracking.A cost function was con-structed to achieve the high-precision grid-connected control of the CHB inverter.Finally,the effectiveness of the proposed control method was verified through a semi-physical simulation platform with three submodules. 展开更多
关键词 Model predictive control(MPC) Photovoltaic system Cascaded H-bridge(CHB)inverter Capacitor voltage balance
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Predictive value of machine learning models for lymph node metastasis in gastric cancer: A two-center study
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作者 Tong Lu Miao Lu +4 位作者 Dong Wu Yuan-Yuan Ding Hao-Nan Liu Tao-Tao Li Da-Qing Song 《World Journal of Gastrointestinal Surgery》 SCIE 2024年第1期85-94,共10页
BACKGROUND Gastric cancer is one of the most common malignant tumors in the digestive system,ranking sixth in incidence and fourth in mortality worldwide.Since 42.5%of metastatic lymph nodes in gastric cancer belong t... BACKGROUND Gastric cancer is one of the most common malignant tumors in the digestive system,ranking sixth in incidence and fourth in mortality worldwide.Since 42.5%of metastatic lymph nodes in gastric cancer belong to nodule type and peripheral type,the application of imaging diagnosis is restricted.AIM To establish models for predicting the risk of lymph node metastasis in gastric cancer patients using machine learning(ML)algorithms and to evaluate their pre-dictive performance in clinical practice.METHODS Data of a total of 369 patients who underwent radical gastrectomy at the Depart-ment of General Surgery of Affiliated Hospital of Xuzhou Medical University(Xuzhou,China)from March 2016 to November 2019 were collected and retro-spectively analyzed as the training group.In addition,data of 123 patients who underwent radical gastrectomy at the Department of General Surgery of Jining First People’s Hospital(Jining,China)were collected and analyzed as the verifi-cation group.Seven ML models,including decision tree,random forest,support vector machine(SVM),gradient boosting machine,naive Bayes,neural network,and logistic regression,were developed to evaluate the occurrence of lymph node metastasis in patients with gastric cancer.The ML models were established fo-llowing ten cross-validation iterations using the training dataset,and subsequently,each model was assessed using the test dataset.The models’performance was evaluated by comparing the area under the receiver operating characteristic curve of each model.RESULTS Among the seven ML models,except for SVM,the other ones exhibited higher accuracy and reliability,and the influences of various risk factors on the models are intuitive.CONCLUSION The ML models developed exhibit strong predictive capabilities for lymph node metastasis in gastric cancer,which can aid in personalized clinical diagnosis and treatment. 展开更多
关键词 Machine learning Prediction model Gastric cancer Lymph node metastasis
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Establishment of a prognosis predictive model for liver cancer based on expression of genes involved in the ubiquitin-proteasome pathway
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作者 Hua Li Yi-Po Ma +5 位作者 Hai-Long Wang Cai-Juan Tian Yi-Xian Guo Hong-Bo Zhang Xiao-Min Liu Peng-Fei Liu 《World Journal of Clinical Oncology》 2024年第3期434-446,共13页
BACKGROUND The ubiquitin-proteasome pathway(UPP)has been proven to play important roles in cancer.AIM To investigate the prognostic significance of genes involved in the UPP and develop a predictive model for liver ca... BACKGROUND The ubiquitin-proteasome pathway(UPP)has been proven to play important roles in cancer.AIM To investigate the prognostic significance of genes involved in the UPP and develop a predictive model for liver cancer based on the expression of these genes.METHODS In this study,UPP-related E1,E2,E3,deubiquitylating enzyme,and proteasome gene sets were obtained from the Kyoto Encyclopedia of Genes and Genomes(KEGG)database,aiming to screen the prognostic genes using univariate and multivariate regression analysis and develop a prognosis predictive model based RESULTS Five genes(including autophagy related 10,proteasome 20S subunit alpha 8,proteasome 20S subunit beta 2,ubiquitin specific peptidase 17 like family member 2,and ubiquitin specific peptidase 8)were proven significantly correlated with prognosis and used to develop a prognosis predictive model for liver cancer.Among training,validation,and Gene Expression Omnibus sets,the overall survival differed significantly between the high-risk and low-risk groups.The expression of the five genes was significantly associated with immunocyte infiltration,tumor stage,and postoperative recurrence.A total of 111 differentially expressed genes(DEGs)were identified between the high-risk and low-risk groups and they were enriched in 20 and 5 gene ontology and KEGG pathways.Cell division cycle 20,Kelch repeat and BTB domain containing 11,and DDB1 and CUL4 associated factor 4 like 2 were the DEGs in the E3 gene set that correlated with survival.CONCLUSION We have constructed a prognosis predictive model in patients with liver cancer,which contains five genes that associate with immunocyte infiltration,tumor stage,and postoperative recurrence. 展开更多
关键词 Liver cancer Ubiquitin-proteasome pathway Prognosis prediction Gene expression Immune infiltration
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Development and validation of a predictive model for patients with post-extubation dysphagia 被引量:2
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作者 Jia-ying Tang Xiu-qin Feng +5 位作者 Xiao-xia Huang Yu-ping Zhang Zhi-ting Guo Lan Chen Hao-tian Chen Xiao-xiao Ying 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2023年第1期49-55,共7页
BACKGROUND:Swallowing disorder is a common clinical symptom that can lead to a series of complications,including aspiration,aspiration pneumonia,and malnutrition.This study aimed to investigate risk factors of post-ex... BACKGROUND:Swallowing disorder is a common clinical symptom that can lead to a series of complications,including aspiration,aspiration pneumonia,and malnutrition.This study aimed to investigate risk factors of post-extubation dysphagia(PED)in intensive care unit(ICU)patients with endotracheal intubation,and to develop a risk-predictive model for PED,which could serve as an assessment tool for the prevention and control of PED.METHODS:Patients retrospectively selected from June to December 2021 in a tertiary hospital served as the derivation cohort.Patients recruited from the same hospital from March to June 2022served as the external validation cohort for the predictive model.We used a combination of variable screening and least absolute shrinkage and selection operator(LASSO)regression to select the most useful candidate predictors and checked the multicollinearity of independent variables using the variance inflation factor method.Multivariate logistic regression analysis was performed to calculate the odds ratio(OR;95%confidence interval[95%CI])and P-value for each variable to predict diagnosis.The screened risk factors were introduced into R software to build a nomogram model.The performance of the model,including discrimination ability,calibration,and clinical benefit,was evaluated by plotting the receiver operating characteristic(ROC),calibration,and decision curves.RESULTS:A total of 305 patients were included in this study.Among them,235 patients(53PED vs.182 non-PED)were enrolled in the derivation cohort,while 70 patients(17 PED vs.53 nonPED)were enrolled in the validation cohort.The independent predictors included age,pause of sedatives,level of consciousness,activities of daily living(ADL)score,nasogastric tube,sore throat,and voice disorder.These predictors were used to establish the predictive nomogram model.The model demonstrated good discriminative ability,and the area under the ROC curve(AUC)was 0.945(95%CI 0.904-0.970).Applying the predictive model to the validation cohort demonstrated good discrimination with an AUC of 0.907(95%CI 0.831-0.983)and good calibration.The decision-curve analysis of this nomogram showed a net benefit of the model.CONCLUSION:A predictive model that incorporates age,pause of sedatives,level of consciousness,ADL score,nasogastric tube,sore throat,and voice disorder may have the potential to predict PED in ICU patients. 展开更多
关键词 Post-extubation dysphagia NOMOGRAM predictive model
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Development and validation of a predictive model for the assessment of potassium-lowering treatment among hyperkalemia patients 被引量:1
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作者 Cong-ying Song Jian-yong Zhu +1 位作者 Wei Huang Yuan-qiang Lu 《World Journal of Emergency Medicine》 SCIE CAS CSCD 2023年第3期198-203,共6页
BACKGROUND:Hyperkalemia is common among patients in emergency department and is associated with mortality.While,there is a lack of good evaluation and prediction methods for the effi cacy of potassium-lowering treatme... BACKGROUND:Hyperkalemia is common among patients in emergency department and is associated with mortality.While,there is a lack of good evaluation and prediction methods for the effi cacy of potassium-lowering treatment,making the drug dosage adjustment quite diffi cult.We aimed to develop a predictive model to provide early forecasting of treating eff ects for hyperkalemia patients.METHODS:Around 80%of hyperkalemia patients(n=818)were randomly selected as the training dataset and the remaining 20%(n=196)as the validating dataset.According to the serum potassium(K+)levels after the fi rst round of potassium-lowering treatment,patients were classifi ed into the eff ective and ineff ective groups.Multivariate logistic regression analyses were performed to develop a prediction model.The receiver operating characteristic(ROC)curve and calibration curve analysis were used for model validation.RESULTS:In the training dataset,429 patients had favorable eff ects after treatment(eff ective group),and 389 had poor therapeutic outcomes(ineff ective group).Patients in the ineff ective group had a higher percentage of renal disease(P=0.007),peripheral edema(P<0.001),oliguria(P=0.001),or higher initial serum K+level(P<0.001).The percentage of insulin usage was higher in the effective group than in the ineff ective group(P=0.005).After multivariate logistic regression analysis,we found age,peripheral edema,oliguria,history of kidney transplantation,end-stage renal disease,insulin,and initial serum K+were all independently associated with favorable treatment eff ects.CONCLUSION:The predictive model could provide early forecasting of therapeutic outcomes for hyperkalemia patients after drug treatment,which could help clinicians to identify hyperkalemia patients with high risk and adjust the dosage of medication for potassium-lowering. 展开更多
关键词 HYPERKALEMIA predictive model Potassium-lowering treatment Therapeutic outcome
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Machine Learning Accelerated Real-Time Model Predictive Control for Power Systems 被引量:1
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作者 Ramij Raja Hossain Ratnesh Kumar 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第4期916-930,共15页
This paper presents a machine-learning-based speedup strategy for real-time implementation of model-predictive-control(MPC)in emergency voltage stabilization of power systems.Despite success in various applications,re... This paper presents a machine-learning-based speedup strategy for real-time implementation of model-predictive-control(MPC)in emergency voltage stabilization of power systems.Despite success in various applications,real-time implementation of MPC in power systems has not been successful due to the online control computation time required for large-sized complex systems,and in power systems,the computation time exceeds the available decision time used in practice by a large extent.This long-standing problem is addressed here by developing a novel MPC-based framework that i)computes an optimal strategy for nominal loads in an offline setting and adapts it for real-time scenarios by successive online control corrections at each control instant utilizing the latest measurements,and ii)employs a machine-learning based approach for the prediction of voltage trajectory and its sensitivity to control inputs,thereby accelerating the overall control computation by multiple times.Additionally,a realistic control coordination scheme among static var compensators(SVC),load-shedding(LS),and load tap-changers(LTC)is presented that incorporates the practical delayed actions of the LTCs.The performance of the proposed scheme is validated for IEEE 9-bus and 39-bus systems,with±20%variations in nominal loading conditions together with contingencies.We show that our proposed methodology speeds up the online computation by 20-fold,bringing it down to a practically feasible value(fraction of a second),making the MPC real-time and feasible for power system control for the first time. 展开更多
关键词 Machine learning model predictive control(MPC) neural network perturbation control voltage stabilization
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DC active power filter based on model predictive control for DC bus overvoltage suppression of accelerator grid power supply 被引量:1
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作者 张鸿淇 朱帮友 +3 位作者 马少翔 李志恒 张明 潘垣 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第6期1-13,共13页
The China Fusion Engineering Test Reactor plans to build a 200 k V/25 A acceleration grid power supply(AGPS)for the negative-ion-based neutral beam injector prototype system.The AGPS uses a rectifier-inverter-isolated... The China Fusion Engineering Test Reactor plans to build a 200 k V/25 A acceleration grid power supply(AGPS)for the negative-ion-based neutral beam injector prototype system.The AGPS uses a rectifier-inverter-isolated step-up structure.There is a DC bus between the rectifier and the inverter.In order to limit DC bus voltage ripple and transient fluctuations,a large number of capacitors are used,which degrades the reliability of the power supply and occupies a large amount of space.This work finds that due to the difference in the turn-off time of the rectifier and the inverter,the capacitance mainly depends on the rectifier current when the inverter is turned off.On this basis,an active power filter(APF)scheme is proposed to absorb the current.To enhance the dynamic response ability of the APF,model predictive control is adopted.In this paper,the circuit structure of the APF is introduced,the prediction model is deduced,the corresponding control strategy and signal detection method are proposed,and the simulation and experimental results show that APF can track the transient current of the DC bus and reduce the voltage fluctuation significantly. 展开更多
关键词 CFETR NBI accelerator grid power supply power active filter model predictive control
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Tracking Control of Multi-Agent Systems Using a Networked Predictive PID Tracking Scheme 被引量:1
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作者 Guo-Ping Liu 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第1期216-225,共10页
With the rapid development of network technology and control technology,a networked multi-agent control system is a key direction of modern industrial control systems,such as industrial Internet systems.This paper stu... With the rapid development of network technology and control technology,a networked multi-agent control system is a key direction of modern industrial control systems,such as industrial Internet systems.This paper studies the tracking control problem of networked multi-agent systems with communication constraints,where each agent has no information on the dynamics of other agents except their outputs.A networked predictive proportional integral derivative(PPID)tracking scheme is proposed to achieve the desired tracking performance,compensate actively for communication delays,and simplify implementation in a distributed manner.This scheme combines the past,present and predictive information of neighbour agents to form a tracking error signal for each agent,and applies the proportional,integral,and derivative of the agent tracking error signal to control each individual agent.The criteria of the stability and output tracking consensus of multi-agent systems with the networked PPID tracking scheme are derived through detailed analysis on the closed-loop systems.The effectiveness of the networked PPID tracking scheme is illustrated via an example. 展开更多
关键词 Coordinative tracking control networked multiagent systems PID control predictive control
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Multiobjective economic model predictive control using utopia-tracking for the wet flue gas desulphurization system
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作者 Shan Liu Wenqi Zhong +2 位作者 Xi Chen Li Sun Lukuan Yang 《Chinese Journal of Chemical Engineering》 SCIE EI CAS CSCD 2023年第2期343-352,共10页
Efficient control of the desulphurization system is challenging in maximizing the economic objective while reducing the SO_(2) emission concentration. The conventional optimization method is generally based on a hiera... Efficient control of the desulphurization system is challenging in maximizing the economic objective while reducing the SO_(2) emission concentration. The conventional optimization method is generally based on a hierarchical structure in which the upper optimization layer calculates the steady-state results and the lower control layer is responsible to drive the process to the target point. However, the conventional hierarchical structure does not take the economic performance of the dynamic tracking process into account. To this end, multi-objective economic model predictive control(MOEMPC) is introduced in this paper, which unifies the optimization and control layers in a single stage. The objective functions are formulated in terms of a dynamic horizon and to balance the stability and economic performance. In the MOEMPC scheme, economic performance and SO_(2) emission performance are guaranteed by tracking a set of utopia points during dynamic transitions. The terminal penalty function and stabilizing constraint conditions are designed to ensure the stability of the system. Finally, an optimized control method for the stable operation of the complex desulfurization system has been established. Simulation results demonstrate that MOEMPC is superior over another control strategy in terms of economic performance and emission reduction, especially when the desulphurization system suffers from frequent flue gas disturbances. 展开更多
关键词 Desulphurization system Economics Economic model predictive control Flue gas Optimization Utopia point
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Connectivity-maintaining Consensus of Multi-agent Systems With Communication Management Based on Predictive Control Strategy
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作者 Jie Wang Shaoyuan Li Yuanyuan Zou 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2023年第3期700-710,共11页
This paper studies the connectivity-maintaining consensus of multi-agent systems.Considering the impact of the sensing ranges of agents for connectivity and communication energy consumption,a novel communication manag... This paper studies the connectivity-maintaining consensus of multi-agent systems.Considering the impact of the sensing ranges of agents for connectivity and communication energy consumption,a novel communication management strategy is proposed for multi-agent systems so that the connectivity of the system can be maintained and the communication energy can be saved.In this paper,communication management means a strategy about how the sensing ranges of agents are adjusted in the process of reaching consensus.The proposed communication management in this paper is not coupled with controller but only imposes a constraint for controller,so there is more freedom to develop an appropriate control strategy for achieving consensus.For the multi-agent systems with this novel communication management,a predictive control based strategy is developed for achieving consensus.Simulation results indicate the effectiveness and advantages of our scheme. 展开更多
关键词 CONSENSUS ENERGY-SAVING multi-agent system predictive control
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