Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who atte...Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown.This observational cross-sectional study enrolled 41 young Internet addicts,aged from 15 to 20 years,from the Department of Psychiatry,the First Affiliated Hospital of Chongqing Medical University,China from January to May 2018.The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history.Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner.The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group.In the resting state,the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities,which may provide a new basis for studying suicide pathogenesis in Internet addicts.The study was authorized by the Ethics Committee of Chongqing Medical University,China(approval No.2017 Scientific Research Ethics(2017-157))on December 11,2017.展开更多
Objective To explore the effect of low-frequency magnetic stimulation at Shenmen(HT 7)acupoint on blood oxygen levels in the prefrontal cortex of healthy subjects.Methods Functional near-infrared spectroscopy(fNIRS)te...Objective To explore the effect of low-frequency magnetic stimulation at Shenmen(HT 7)acupoint on blood oxygen levels in the prefrontal cortex of healthy subjects.Methods Functional near-infrared spectroscopy(fNIRS)technology was used to collect real-time data of oxygenated hemoglobin(oxy-Hb)in the prefrontal cortex of 16 healthy subjects at resting state and low-frequency magnetic stimulation of Shenmen.The mean and integral values of blood oxygen concentration were analyzed.Results Compared with the resting state,the mean and integral values of blood oxygen concentration were decreased during the task period,recovery period,and the whole process in the magnetic stimulation of Shenmen acupoint(P<0.05).In particular,the difference was statistically significant in the recovery period(P<0.01).Conclusions The prefrontal cortex was widely activated and produced an immediate effect by reducing the local blood oxygen concentration at low-frequency magnetic stimulation of Shenmen acupoint,which verifies the sedative effect of Shenmen acupoint.展开更多
基金supported by a grant from Chongqing Science and Technology Commission of China,Nos.CSTC2018jxj1130009,cstc2019 jscx-msxmX0279(both to YH)the Traditional Chinese Medicine Scientific Research Fund from Chongqing Health Committee of China,No.2019ZY023315(to YH)
文摘Internet addiction is associated with an increased risk of suicidal behavior and can lead to brain dysfunction among adolescents.However,whether brain dysfunction occurs in adolescents with Internet addiction who attempt suicide remains unknown.This observational cross-sectional study enrolled 41 young Internet addicts,aged from 15 to 20 years,from the Department of Psychiatry,the First Affiliated Hospital of Chongqing Medical University,China from January to May 2018.The participants included 21 individuals who attempted suicide and 20 individuals with Internet addiction without a suicidal attempt history.Brain images in the resting state were obtained by a 3.0 T magnetic resonance imaging scanner.The results showed that activity in the gyrus frontalis inferior of the right pars triangularis and the right pars opercularis was significantly increased in the suicidal attempt group compared with the non-suicidal attempt group.In the resting state,the prefrontal lobe of adolescents who had attempted suicide because of Internet addiction exhibited functional abnormalities,which may provide a new basis for studying suicide pathogenesis in Internet addicts.The study was authorized by the Ethics Committee of Chongqing Medical University,China(approval No.2017 Scientific Research Ethics(2017-157))on December 11,2017.
基金Supported by the National Natural Science Foundation of China(No.81873354)Ministry of Science and Technology of Shaanxi Province(No.2018ZDXM-SF-013,No.2020SF-342)。
文摘Objective To explore the effect of low-frequency magnetic stimulation at Shenmen(HT 7)acupoint on blood oxygen levels in the prefrontal cortex of healthy subjects.Methods Functional near-infrared spectroscopy(fNIRS)technology was used to collect real-time data of oxygenated hemoglobin(oxy-Hb)in the prefrontal cortex of 16 healthy subjects at resting state and low-frequency magnetic stimulation of Shenmen.The mean and integral values of blood oxygen concentration were analyzed.Results Compared with the resting state,the mean and integral values of blood oxygen concentration were decreased during the task period,recovery period,and the whole process in the magnetic stimulation of Shenmen acupoint(P<0.05).In particular,the difference was statistically significant in the recovery period(P<0.01).Conclusions The prefrontal cortex was widely activated and produced an immediate effect by reducing the local blood oxygen concentration at low-frequency magnetic stimulation of Shenmen acupoint,which verifies the sedative effect of Shenmen acupoint.
