Lipase catalyzed acetylation of 2 afforded 3 with the e.e. up to 98%. Utility of 3 was illustrated by the preparation of Prelog-Djerassi lactones 7a and 7b.
During the course of our program in the synthesis of natural products by retroDiels-Alder reaction using a rigid molecule tricyclo-[5.2.1.0]-deca-4,8-dien-3-one（1） as the starting material, it was observed that aldo...During the course of our program in the synthesis of natural products by retroDiels-Alder reaction using a rigid molecule tricyclo-[5.2.1.0]-deca-4,8-dien-3-one（1） as the starting material, it was observed that aldol condensation of compound （2）展开更多
基金Project supported by the National Natural Science Foundation of China.
文摘Lipase catalyzed acetylation of 2 afforded 3 with the e.e. up to 98%. Utility of 3 was illustrated by the preparation of Prelog-Djerassi lactones 7a and 7b.
基金supported by the national Natural Science Foundation of China.
文摘During the course of our program in the synthesis of natural products by retroDiels-Alder reaction using a rigid molecule tricyclo-[5.2.1.0]-deca-4,8-dien-3-one（1） as the starting material, it was observed that aldol condensation of compound （2）
