To extend the service life of the clinched joint,a reconditioning process conducted with an additional tubular rivet was proposed in this work.Different reconditioning forces were employed to produce dissimilar recond...To extend the service life of the clinched joint,a reconditioning process conducted with an additional tubular rivet was proposed in this work.Different reconditioning forces were employed to produce dissimilar reconditioned joints by experimental method.The experimental results indicated that the neck fracture was the common failure mode of both original clinched and reconditioned joints.Compared with the original clinched joint,the shearing strength of the reconditioned joint produced by a reconditioning force of 40 kN increased from 1810.5 to 1986.47 N,and the energy absorption increased from 2.34 to 3.46 J.The range of effective reconditioning force was from 35 to 40 kN and 40 kN was the best choice for reconditioning the AA5052 failed joints.The mechanical properties of the reconditioned joints are obviously better than those of the original clinched joints,which fully demonstrates that the reconditioning method proposed in this work has a broad prospect of industrial application.展开更多
The maintenance management of construction equipment occupies a prominent place in the overall strategy for managing the equipment fleet. It is also linked to the management of the stock of spare parts and particularl...The maintenance management of construction equipment occupies a prominent place in the overall strategy for managing the equipment fleet. It is also linked to the management of the stock of spare parts and particularly reconditioned spare parts. Because of the relatively low purchase cost of these, most companies are tempted by this option. The purpose of this article is precisely to study the impact of this category of parts in the stock and also in the optimization of maintenance costs, knowing that to do this;their use must obey certain constraints. It is therefore important to be able to characterize these reconditioned parts by estimating their optimal age, and studying their advantages and also their limits. The determination of the optimal age of reconditioned parts will be such that the total cost of replacement with used parts is at most equal to the total cost of replacement with new parts at the end of the operating period.展开更多
Longstanding research describes the mechanisms whereby the restoration of blood flow and reoxygenation(reperfusion) aggravates the ischaemic injury caused by a period of anoxia to a donor liver. This phenomenon, calle...Longstanding research describes the mechanisms whereby the restoration of blood flow and reoxygenation(reperfusion) aggravates the ischaemic injury caused by a period of anoxia to a donor liver. This phenomenon, called ischaemia-reperfusion injury(IRI), leads to parenchymal cell death,microcirculatory failure, and inflammatory immune response. Clinically, IRI is the main factor responsible for the occurrence of posttransplant graft dysfunction and ischaemic-type biliary lesions. While extended criteria donor livers are more vulnerable to IRI, their utilisation is required to address the shortfall in donor organs. Thus, the mitigation of IRI should drive the setting of a new benchmark for marginal organ preservation. Herein, strategies incorporating different modalities of machine perfusion of the liver to alleviate IRI are discussed in conjunction with advantages and disadvantages of individual protocols.Techniques leading to reperfusion of the liver during machine perfusion(in situ normothermic regional perfusion and ex situ normothermic machine perfusion)may mitigate IRI by shortening the ischaemic period of the organs. This benefit potentially escalates from the minimum level, obtained following just partial alleviation of the ischaemic period, to the maximum level, which can be potentially achieved with ischaemia-free organ transplantation. Techniques that do not lead to reperfusion of the liver during machine perfusion(hypothermic,subnormothermic, and controlled-oxygenated rewarming) optimise mitochondrial oxidative function and replenish cellular energy stores, thereby lowering reactive oxygen species production as well as the activation ofdownstream inflammatory pathways during reperfusion. Further mechanistic insights into IRI may guide the development of donor-specific protocols of machine perfusion on the basis of the limitations of individual categories of extended criteria donor organs.展开更多
Therapeutic Acupunctural Resonance was first introduced in the academic field in 2015 and was positively welcomed by colleagues all around the world. However, I have decided to do further research going deeply into ne...Therapeutic Acupunctural Resonance was first introduced in the academic field in 2015 and was positively welcomed by colleagues all around the world. However, I have decided to do further research going deeply into new and more precise explanations which no longer refer to the effects of this particular treatment, but to how this technique works in the practice of Chinese Medicine. Being able to understand Therapeutic Acupunctural Resonance implies analyzing a series of phenomena related to historic landmarks of Classical Physics, as well as avant-garde theories within Quantum Physics and its theory of fields.展开更多
The Chinese managed to interpret not only the natural rhythms of cosmic and seasonal cycles but the chrono-biological rhythms present in human body. What since long ago was merely taken to be a pre-scientific traditio...The Chinese managed to interpret not only the natural rhythms of cosmic and seasonal cycles but the chrono-biological rhythms present in human body. What since long ago was merely taken to be a pre-scientific tradition has currently become a tangible reality. Nowadays, the specific frequencies pulsating along each meridian can be measured in hertz—according to its own resonance—as Acupuncture determined thousands of years ago. Their effort to establish a taxonomic classification of all environmental and human phenomena is closely related to Mathematics propositions of Euclid Five Regular Polyhedra, in order to consolidate the axiomatic-deductive model which we can now relate to the Chinese Theory of the Five Elements and their constant changes. As presented in OMICS Group Traditional Medicine-2015 Conference in Birmingham, it could be also proved that there also exists an inescapable relationship between Pythagoras and the Mathematical foundation of the Pentatonic Chinese Musical Scale. A simple way to incorporate the ideal frequency rhythm for each channel to correct its unbalanced situation is to insert said frequencies through the needles, by way of “antennae”, restructuring the meridian’s resonance affected and through it, of the Element it belongs to. Therapeutic Acupunctural Resonance therefore finds effective application when pins are used as “resonators”, putting the frequency of said Element of the channel in line, so that they transmit by means of punctures pure vibratory patterns which shall recondition the Qi flow frequency which has been altered by the Chinese syndrome diagnosed to be treated.展开更多
基金financial supports from the National Natural Science Foundation of China (No. 51805416)the Young Elite Scientists Sponsorship Program by CAST, China (No. YESS20200279)+3 种基金the Natural Science Foundation of Hunan Province, China (No. 2020JJ5716)the Project of State Key Laboratory of High Performance Complex Manufacturing, Central South University, China (No. ZZYJKT2019-01)the Hunan Provincial Natural Science Foundation for Excellent Young Scholars, China (No. 2021JJ20059)the Huxiang High-Level Talent Gathering Project of Hunan Province, China (No. 2019RS1002)。
文摘To extend the service life of the clinched joint,a reconditioning process conducted with an additional tubular rivet was proposed in this work.Different reconditioning forces were employed to produce dissimilar reconditioned joints by experimental method.The experimental results indicated that the neck fracture was the common failure mode of both original clinched and reconditioned joints.Compared with the original clinched joint,the shearing strength of the reconditioned joint produced by a reconditioning force of 40 kN increased from 1810.5 to 1986.47 N,and the energy absorption increased from 2.34 to 3.46 J.The range of effective reconditioning force was from 35 to 40 kN and 40 kN was the best choice for reconditioning the AA5052 failed joints.The mechanical properties of the reconditioned joints are obviously better than those of the original clinched joints,which fully demonstrates that the reconditioning method proposed in this work has a broad prospect of industrial application.
文摘The maintenance management of construction equipment occupies a prominent place in the overall strategy for managing the equipment fleet. It is also linked to the management of the stock of spare parts and particularly reconditioned spare parts. Because of the relatively low purchase cost of these, most companies are tempted by this option. The purpose of this article is precisely to study the impact of this category of parts in the stock and also in the optimization of maintenance costs, knowing that to do this;their use must obey certain constraints. It is therefore important to be able to characterize these reconditioned parts by estimating their optimal age, and studying their advantages and also their limits. The determination of the optimal age of reconditioned parts will be such that the total cost of replacement with used parts is at most equal to the total cost of replacement with new parts at the end of the operating period.
基金supported by the NIHR Birmingham Biomedical Research Centre at the University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham
文摘Longstanding research describes the mechanisms whereby the restoration of blood flow and reoxygenation(reperfusion) aggravates the ischaemic injury caused by a period of anoxia to a donor liver. This phenomenon, called ischaemia-reperfusion injury(IRI), leads to parenchymal cell death,microcirculatory failure, and inflammatory immune response. Clinically, IRI is the main factor responsible for the occurrence of posttransplant graft dysfunction and ischaemic-type biliary lesions. While extended criteria donor livers are more vulnerable to IRI, their utilisation is required to address the shortfall in donor organs. Thus, the mitigation of IRI should drive the setting of a new benchmark for marginal organ preservation. Herein, strategies incorporating different modalities of machine perfusion of the liver to alleviate IRI are discussed in conjunction with advantages and disadvantages of individual protocols.Techniques leading to reperfusion of the liver during machine perfusion(in situ normothermic regional perfusion and ex situ normothermic machine perfusion)may mitigate IRI by shortening the ischaemic period of the organs. This benefit potentially escalates from the minimum level, obtained following just partial alleviation of the ischaemic period, to the maximum level, which can be potentially achieved with ischaemia-free organ transplantation. Techniques that do not lead to reperfusion of the liver during machine perfusion(hypothermic,subnormothermic, and controlled-oxygenated rewarming) optimise mitochondrial oxidative function and replenish cellular energy stores, thereby lowering reactive oxygen species production as well as the activation ofdownstream inflammatory pathways during reperfusion. Further mechanistic insights into IRI may guide the development of donor-specific protocols of machine perfusion on the basis of the limitations of individual categories of extended criteria donor organs.
文摘Therapeutic Acupunctural Resonance was first introduced in the academic field in 2015 and was positively welcomed by colleagues all around the world. However, I have decided to do further research going deeply into new and more precise explanations which no longer refer to the effects of this particular treatment, but to how this technique works in the practice of Chinese Medicine. Being able to understand Therapeutic Acupunctural Resonance implies analyzing a series of phenomena related to historic landmarks of Classical Physics, as well as avant-garde theories within Quantum Physics and its theory of fields.
文摘The Chinese managed to interpret not only the natural rhythms of cosmic and seasonal cycles but the chrono-biological rhythms present in human body. What since long ago was merely taken to be a pre-scientific tradition has currently become a tangible reality. Nowadays, the specific frequencies pulsating along each meridian can be measured in hertz—according to its own resonance—as Acupuncture determined thousands of years ago. Their effort to establish a taxonomic classification of all environmental and human phenomena is closely related to Mathematics propositions of Euclid Five Regular Polyhedra, in order to consolidate the axiomatic-deductive model which we can now relate to the Chinese Theory of the Five Elements and their constant changes. As presented in OMICS Group Traditional Medicine-2015 Conference in Birmingham, it could be also proved that there also exists an inescapable relationship between Pythagoras and the Mathematical foundation of the Pentatonic Chinese Musical Scale. A simple way to incorporate the ideal frequency rhythm for each channel to correct its unbalanced situation is to insert said frequencies through the needles, by way of “antennae”, restructuring the meridian’s resonance affected and through it, of the Element it belongs to. Therapeutic Acupunctural Resonance therefore finds effective application when pins are used as “resonators”, putting the frequency of said Element of the channel in line, so that they transmit by means of punctures pure vibratory patterns which shall recondition the Qi flow frequency which has been altered by the Chinese syndrome diagnosed to be treated.
