High-performance microwave absorption(MA) materials must be studied immediately since electromagnetic pollution has become a problem that cannot be disregarded. A straightforward composite material, comprising hollow ...High-performance microwave absorption(MA) materials must be studied immediately since electromagnetic pollution has become a problem that cannot be disregarded. A straightforward composite material, comprising hollow MXene spheres loaded with C–Co frameworks, was prepared to develop multiwalled carbon nanotubes(MWCNTs). A high impedance and suitable morphology were guaranteed by the C–Co exoskeleton, the attenuation ability was provided by the MWCNTs endoskeleton, and the material performance was greatly enhanced by the layered core–shell structure. When the thickness was only 2.04 mm, the effective absorption bandwidth was 5.67 GHz, and the minimum reflection loss(RLmin) was-70.70 d B. At a thickness of 1.861 mm, the sample calcined at 700 ℃ had a RLmin of-63.25 d B. All samples performed well with a reduced filler ratio of 15 wt%. This paper provides a method for making lightweight core–shell composite MA materials with magnetoelectric synergy.展开更多
Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced safety.Howev...Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced safety.However,developing high-performance anode materials to improve sodium storage performa nce still remains a major challenge.Here,a facile one-pot method has been developed to fabricate a hybrid of MoSeTe nanosheets implanted within the N,F co-doped honeycomb carbon skeleton(MoSeTe/N,F@C).Experimental results demonstrate that the incorporation of large-sized Te atoms into MoSeTe nanosheets enlarges the layer spacing and creates abundant anion vacancies,which effectively facilitate the insertion/extraction of Na^(+) and provide numerous ion adsorption sites for rapid surface capacitive behavior.Additionally,the heteroatoms N,F co-doped honeycomb carbon skeleton with a highly conductive network can restrain the volume expansion and boost reaction kinetics within the electrode.As anticipated,the MoSeTe/N,F@C anode exhibits high reversible capacities along with exceptional cycle stability.When coupled with Na_(3)V_(2)(PO_(4))_(3)@C(NVPF@C) to form SIB full cells,the anode delivers a reversible specific capacity of 126 mA h g^(-1) after 100 cycles at 0.1 A g^(-1).Furthermore,when combined with AC to form SIHC full cells,the anode demonstrates excellent cycling stability with a reversible specific capacity of50 mA h g^(-1) keeping over 3700 cycles at 1.0 A g^(-1).In situ XRD,ex situ TEM characterization,and theoretical calculations(DFT) further confirm the reversibility of sodium storage in MoSeTe/N,F@C anode materials during electrochemical reactions,highlighting their potential for widespread practical application.This work provides new insights into the promising utilization of advanced transition metal dichalcogenides as anode materials for Na^(+)-based energy storage devices.展开更多
Composite polymer electrolytes(CPEs)are considered to be the most promising to break through the performance and safety limitations of traditional lithium-ion batteries because of their excellent electrochemical and m...Composite polymer electrolytes(CPEs)are considered to be the most promising to break through the performance and safety limitations of traditional lithium-ion batteries because of their excellent electrochemical and mechanical properties.Aiming at the performance limitations of the most common polyether matrix such as poly(ethylene oxide)(PEO),a novel poly(cyclocarbonate-ether)polymer matrix was prepared by in-situ thermal curing,the weaker interaction between its C=O bond and Li^(+)can promote the rapid transport of Li^(+).Adding ionic liquid and active filler LLZTO to the matrix can synergistically reduce the crystallinity of matrix and promote the dissociation of lithium salts.In addition,a 3D functional skeleton made of polyacrylonitrile(PAN)and lithium fluoride(LiF)can greatly improve the mechanical strength of polymer matrix after cold pressing,and Li F is also conducive to interface stability.The thickness of the optimal sample(VP6L/CPL)was only 25μm,and its ionic conductivity,lithium ion transference number,and electrochemical stability window were as high as 7.17×10^(-4)S cm^(-1)(25℃),0.54 and 5.4 V,respectively,while the mechanical strength reaches 6.1 MPa,which can fully inhibit the growth of lithium dendrites.The excellent electrochemical performance and mechanical strength enable the assembled Li|VP6L/CPL|Li battery to be continuously charged for over 200 h and cycled stably for more than 2300 h,and Li|VP6L/CPL|LFP battery can be stably cycled for more than 400 and 550 cycles at 1 C(40℃)and 0.5 C(25℃),respectively.展开更多
A growing number of studies have demonstrated that the skeleton is an endocrine organ that is involved in glucose metabolism and plays a significant role in human glucose homeostasis.However,there is still a limited u...A growing number of studies have demonstrated that the skeleton is an endocrine organ that is involved in glucose metabolism and plays a significant role in human glucose homeostasis.However,there is still a limited understanding of the in vivo glucose uptake and distribution across the human skeleton.To address this issue,we aimed to elucidate the detailed profile of glucose uptake across the skeleton using a total-body positron emission tomography(PET)scanner.A total of 41 healthy participants were recruited.Two of them received a 1-hour dynamic total-body^(18)F-fluorodeoxyglucose(^(18)F-FDG)PET scan,and all of them received a10-minute static total-body^(18)F-FDG PET scan.The net influx rate(K_i)and standardized uptake value normalized by lean body mass(SUL)were calculated as indicators of glucose uptake from the dynamic and static PET data,respectively.The results showed that the vertebrae,hip bone and skull had relatively high Kiand SUL values compared with metabolic organs such as the liver.Both the K_(i) and SUL were higher in the epiphyseal,metaphyseal and cortical regions of long bones.Moreover,trends associated with age and overweight with glucose uptake(SUL_(max)and SUL_(mean))in bones were uncovered.Overall,these results indicate that the skeleton is a site with significant glucose uptake,and skeletal glucose uptake can be affected by age and dysregulated metabolism.展开更多
In this study,a new energetic hybrid skeleton was constructed through the integration of nitropyrazole and 1,3,4-oxadiazole skeletons in a molecule.Furthermore,the energetic precursor(2),the azo-bridged compound(3),th...In this study,a new energetic hybrid skeleton was constructed through the integration of nitropyrazole and 1,3,4-oxadiazole skeletons in a molecule.Furthermore,the energetic precursor(2),the azo-bridged compound(3),the neutral nitramine(4)and the corresponding energetic salts(5-7)were synthesized.Their physicochemical and energetic properties we re experimentally and theo retically evaluated.Among the developed compounds,the azo-bridged compound(3)and dihydroxylammoinium(6)display high detonation performances(3,D_(v)=8904 m/s,P=34.47 GPa;6,D_(v)=9025 m/s,P=34.66 GPa),moderate sensitivities(3,IS=16 J,FS=120 N;6,IS=20 J,FS=312 N)and good densities(3,1.87 g/cm^(3);6,1.81 g/cm^(3)),which indicates that they have the potential to replace the traditional high-energy explosive RDX.The results show that the integration of different energetic skeletons can achieve a good balance between energy and sensitivity.展开更多
In light of the low yields and complex reaction routes of some well-known 5,5-fused and 5,6-fused bicyclic compounds,a series of 5,7-fused bicyclic imidazole-diazepine compounds were developed with high yields by only...In light of the low yields and complex reaction routes of some well-known 5,5-fused and 5,6-fused bicyclic compounds,a series of 5,7-fused bicyclic imidazole-diazepine compounds were developed with high yields by only two efficient steps.Significantly,the seven-membered heterocyclic ring has a stable energetic skeleton with multiple modifiable sites.However,the 5,7-fused bicyclic energetic compounds were rarely reported in the area of energetic materials.Three neutral compounds 1,2 and 4 were synthesized in this work.To improve the detonation performances of the 5,7-fused neutral compounds,corresponding perchlorate 1a and 2a were further developed.The physicochemical and energetic performances of all newly developed compounds were experimentally determined.All newly prepared energetic compounds exhibit high decomposition temperatures(Td:243.8-336℃)and low mechanical sensitivities(IS:>15 J,FS:>280 N).Among them,the velocities performances of 1a(Dv=7651 m/s)and 4(Dv=7600 m/s)are comparable to that of typical heat-resistant energetic material HNS(Dv=7612 m/s).Meanwhile,the high decomposition temperature and low mechanical sensitivities(Td=336℃;IS=32 J;FS>353 N)of 4 are superior to that of HNS(Td=318℃;IS=5 J;FS=250 N).Hence,the 5,7-fused bicyclic compounds with high thermostability,low sensitivities and adjustable detonation performance have a clear tendency to open up a new space for the development of heat-resistant energetic materials.展开更多
To meet the low-cost concept advocated by the sodium metal anode,this paper reports the use of a pulsed electrodeposition technology with ionic liquids as electrolytes to achieve uniform nanoplating of metallic magnes...To meet the low-cost concept advocated by the sodium metal anode,this paper reports the use of a pulsed electrodeposition technology with ionic liquids as electrolytes to achieve uniform nanoplating of metallic magnesium films at around 20 nm on spaced titanium dioxide(TiO_(2))nanotubes(STNA-Mg).First,the sodiophilic magnesium metal coating can effectively reduce the nucleation overpotential of sodium metal.Moreover,three-dimensional STNA can limit the volume expansion during sodium metal plating and stripping to achieve the ultrastable deposition and stripping of sodium metals with a high Coulombic efficiency of up to 99.5%and a small voltage polarization of 5 mV in symmetric Na||Na batteries.In addition,the comparative study of sodium metal deposition behavior of STNA-Mg and STNA-Cu prepared by the same route further confirmed the advantage of magnesium metal to guide sodium metal growth.Finally,the prepared STNA-Mg-Na metal anode and commercial sodium vanadium phosphate cathode were assembled into a full cell,delivering a discharge capacity of 110.2 mAh·g^(-1)with a retention rate of 95.6%after 110 cycles at 1C rate.展开更多
Video-based action recognition is becoming a vital tool in clinical research and neuroscientific study for disorder detection and prediction.However,action recognition currently used in non-human primate(NHP)research ...Video-based action recognition is becoming a vital tool in clinical research and neuroscientific study for disorder detection and prediction.However,action recognition currently used in non-human primate(NHP)research relies heavily on intense manual labor and lacks standardized assessment.In this work,we established two standard benchmark datasets of NHPs in the laboratory:Monkeyin Lab(Mi L),which includes 13 categories of actions and postures,and MiL2D,which includes sequences of two-dimensional(2D)skeleton features.Furthermore,based on recent methodological advances in deep learning and skeleton visualization,we introduced the Monkey Monitor Kit(Mon Kit)toolbox for automatic action recognition,posture estimation,and identification of fine motor activity in monkeys.Using the datasets and Mon Kit,we evaluated the daily behaviors of wild-type cynomolgus monkeys within their home cages and experimental environments and compared these observations with the behaviors exhibited by cynomolgus monkeys possessing mutations in the MECP2 gene as a disease model of Rett syndrome(RTT).Mon Kit was used to assess motor function,stereotyped behaviors,and depressive phenotypes,with the outcomes compared with human manual detection.Mon Kit established consistent criteria for identifying behavior in NHPs with high accuracy and efficiency,thus providing a novel and comprehensive tool for assessing phenotypic behavior in monkeys.展开更多
Lattice structures with excellent physical properties have attracted great research interest.In this paper,a novel volume parametric modeling method based on the skeleton model is proposed for the construction of thre...Lattice structures with excellent physical properties have attracted great research interest.In this paper,a novel volume parametric modeling method based on the skeleton model is proposed for the construction of threedimensional lattice structures.The skeleton model is divided into three types of nodes.And the corresponding algorithms are utilized to construct diverse types of volume parametric nodes.The unit-cell is assembled with distinct nodes according to the geometric features.The final lattice structure is created by the periodic arrangement of unit-cells.Several different types of volume parametric lattice structures are constructed to prove the stability and applicability of the proposed method.The quality is assessed in terms of the value of the Jacobian matrix.Moreover,the volume parametric lattice structures are tested with the isogeometric analysis to verify the feasibility of integration of modeling and simulation.展开更多
The traditional nano-sintering or TLP techniques are generally expensive,time-consuming,and hence unsuitable for realizing practical mass production.Herein,we have developed an improved TLP process to rapidly produce ...The traditional nano-sintering or TLP techniques are generally expensive,time-consuming,and hence unsuitable for realizing practical mass production.Herein,we have developed an improved TLP process to rapidly produce IMC-skeleton structures across the bonding region by initiating a localized liquid-solid interaction among micron particles at traditional soldering temperatures.The developed IMC skeletons can reinforce solder alloys and provide remarkable mechanical stability and electrical capabilities at high temperatures.As a result,the IMC-skeleton strengthened interconnections exhibited higher thermal/electrical conductivity,lower hardness and almost doubled strength than traditional full-IMC joints,attaining 87.4 MPa and 30.2 MPa at room condition and 350℃.Meanwhile,the necessary heating time to form metallurgical bonds was shortened,one-fifth of nano-sintering and one-tenth of TLP bonding,and the material cost was significantly reduced.This proposed technique enabled the fast,low-cost manufacturing of electronics that can serve at temperatures as high as 200−350℃.Besides,the interfacial reactions among particles and the correlated phase evolution process were studied in this research.The formation mechanism of IMC skeletons was analyzed.The correlated influencing factors and their effect on the mechanical,thermal and electrical properties of joints were revealed,which may help the design and extensive uses of such techniques in various high-temperature/power applications.展开更多
Compared with RGB videos and images,human bone data is less vulnerable to external factors and has stronger robustness.Therefore,behavior recognition methods based on skeletons are widely studied.Because graph convolu...Compared with RGB videos and images,human bone data is less vulnerable to external factors and has stronger robustness.Therefore,behavior recognition methods based on skeletons are widely studied.Because graph convolution network(GCN)can deal with the irregular topology data of hu-man skeletons very well,more and more researchers apply GCN to human behavior recognition.Tra-ditional graph convolution methods only consider the joints with physical connectivity or the same type when building the behavior recognition model based on human skeletons structure,which cannot capture higher-order information better.To solve this problem,Motif-GCN is used in this paper to ex-tract spatial features.The relationship between the joints with natural connection in the human body is encoded by the first Motif-GCN,and the possible relationship between the unconnected joints in the human skeleton is encoded by the second Motif-GCN.In this way,the relationship between non-physical joints can be strengthened.Then a two stream framework combining joint and bone informa-tion is used to capture more action information.Finally,experiments are conducted on two subdata-sets X-Sub and X-View of NTU-RGB+D,and the accuracy shown in Top-1 classification results is 89.5%and 95.4%respectively.The experimental results are 1.0%and 0.3%higher than those of the 2S-AGCN model respectively.The superiority of this method is also proved by the experimental results.展开更多
Lithium metal batteries are emerging as a strong candidate in the future energy storage market due to its extremely high energy density.However,the uncontrollable lithium dendrites and volume change of lithium metal a...Lithium metal batteries are emerging as a strong candidate in the future energy storage market due to its extremely high energy density.However,the uncontrollable lithium dendrites and volume change of lithium metal anodes severely hinder its application.In this work,the porous Cu skeleton modified with Cu_(6)Sn_(5)layer is prepared via dealloying brass foil following a facile electroless process.The porous Cu skeleton with large specific surface area and high electronic conductivity effectively reduces the local current density.The Cu_(6)Sn_(5)can react with lithium during the discharge process to form lithiophilic Li_(7)Sn_(2)in situ to promote Li-ions transport and reduce the nucleation energy barrier of lithium to guide the uniform lithium deposition.Therefore,more than 300 cycles at 1 mA cm^(−2)are achieved in the half-cell with an average Coulombic efficiency of 97.5%.The symmetric cell shows a superior cycle life of more than 1000 h at 1 mA cm^(−2)with a small average hysteresis voltage of 16 mV.When coupled with LiFePO_(4)cathode,the full cell also maintains excellent cycling and rate performance.展开更多
Background: Off-pump coronary artery bypass grafting (OPCAB) is a surgical procedure that has gained popularity due to its potential benefits over traditional coronary artery bypass grafting, including reduced morbidi...Background: Off-pump coronary artery bypass grafting (OPCAB) is a surgical procedure that has gained popularity due to its potential benefits over traditional coronary artery bypass grafting, including reduced morbidity and mortality. However, sternal wound complication (SWC) remains challenging following the procedure. The technique of left internal mammary artery (LIMA) harvesting has been shown to impact the incidence of SWC. This study aimed to compare the incidence of SWC between two techniques of LIMA harvesting, i.e., skeletonized and pedicled. Methods: The study was conducted at the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, and included 60 patients who underwent OPCAB. The patients were divided into two groups of 30 each based on the technique of LIMA harvesting used, i.e., skeletonized (group A) or pedicled (group B). The postoperative ICU care was given to each patient as per the protocol. The statistical analysis was conducted using the SPSS version 26.0 for Windows software. Results: The results showed that 5 (8.33%) patients developed SWC, with 1 (1.67%) patient in group A and 4 (6.66%) patients in group B. However, the occurrence of SWC was not statistically significant between the two groups (p = 0.35). The mean age, gender distribution, and comorbidities such as hypertension, diabetes, dyslipidemia, and anemia were also not statistically significant between the two groups. The number of smokers was statistically significant between the two groups (p = 0.03), and the occurrence of SWC was found to be higher in smoker patients in group B (p = 0.04). Preoperative and postoperative parameters such as duration of operation, duration of mechanical ventilation, duration of chest drains, duration of the central venous line, and amount of postoperative mediastinal bleeding were also not statistically significant between the two groups. The distribution of wound complications, duration of ICU stays, and hospital stay between the two groups was also not statistically significant. Conclusion: In conclusion, this study found that the incidence of SWC was less in skeletonized LIMA harvesting than in pedicled LIMA harvesting after OPCAB. However, this finding was not statistically significant. Further studies with larger sample sizes may be needed to confirm these results and determine the appropriate technique of LIMA harvesting to decrease the incidence of SWC after OPCAB.展开更多
Action recognition has been recognized as an activity in which individuals’behaviour can be observed.Assembling profiles of regular activities such as activities of daily living can support identifying trends in the ...Action recognition has been recognized as an activity in which individuals’behaviour can be observed.Assembling profiles of regular activities such as activities of daily living can support identifying trends in the data during critical events.A skeleton representation of the human body has been proven to be effective for this task.The skeletons are presented in graphs form-like.However,the topology of a graph is not structured like Euclideanbased data.Therefore,a new set of methods to perform the convolution operation upon the skeleton graph is proposed.Our proposal is based on the Spatial Temporal-Graph Convolutional Network(ST-GCN)framework.In this study,we proposed an improved set of label mapping methods for the ST-GCN framework.We introduce three split techniques(full distance split,connection split,and index split)as an alternative approach for the convolution operation.The experiments presented in this study have been trained using two benchmark datasets:NTU-RGB+D and Kinetics to evaluate the performance.Our results indicate that our split techniques outperform the previous partition strategies and aremore stable during training without using the edge importance weighting additional training parameter.Therefore,our proposal can provide a more realistic solution for real-time applications centred on daily living recognition systems activities for indoor environments.展开更多
基金This work was financially supported by the National Natural Science Foundation of China(52130510,62071120,52075097,52205454,52375413)the Natural Science Foundation of Jiangsu Province(BE2022066,BZ2023043,BK20202006,BK20211562)Science and Technology Program of Suzhou,Jiangsu Province,China(SYG202302).
文摘High-performance microwave absorption(MA) materials must be studied immediately since electromagnetic pollution has become a problem that cannot be disregarded. A straightforward composite material, comprising hollow MXene spheres loaded with C–Co frameworks, was prepared to develop multiwalled carbon nanotubes(MWCNTs). A high impedance and suitable morphology were guaranteed by the C–Co exoskeleton, the attenuation ability was provided by the MWCNTs endoskeleton, and the material performance was greatly enhanced by the layered core–shell structure. When the thickness was only 2.04 mm, the effective absorption bandwidth was 5.67 GHz, and the minimum reflection loss(RLmin) was-70.70 d B. At a thickness of 1.861 mm, the sample calcined at 700 ℃ had a RLmin of-63.25 d B. All samples performed well with a reduced filler ratio of 15 wt%. This paper provides a method for making lightweight core–shell composite MA materials with magnetoelectric synergy.
基金supported by the National Natural Science Foundation of China(No.52002320,and 51972267)the China Postdoctoral Science Foundation(No.2022M712574)+3 种基金the Science Foundation of Shaanxi Province(2022GD-TSLD-18,No.2023-JCZD-03)Natural Science Foundation of Shaanxi Province(No.2022GY-372,2021GY-153)Industrial Projects Foundation of Ankang Science and Technology Bureau(No.AK2020-GY02-2)the Platform Construction Projects and Technology Service Teams of Ankang University(No.2021AYPT12 and 2022TD07)。
文摘Sodium-ion batteries(SIBs) and hybrid capacitors(SIHCs) have garnered significant attention in energy storage due to their inherent advantages,including high energy density,cost-effectiveness,and enhanced safety.However,developing high-performance anode materials to improve sodium storage performa nce still remains a major challenge.Here,a facile one-pot method has been developed to fabricate a hybrid of MoSeTe nanosheets implanted within the N,F co-doped honeycomb carbon skeleton(MoSeTe/N,F@C).Experimental results demonstrate that the incorporation of large-sized Te atoms into MoSeTe nanosheets enlarges the layer spacing and creates abundant anion vacancies,which effectively facilitate the insertion/extraction of Na^(+) and provide numerous ion adsorption sites for rapid surface capacitive behavior.Additionally,the heteroatoms N,F co-doped honeycomb carbon skeleton with a highly conductive network can restrain the volume expansion and boost reaction kinetics within the electrode.As anticipated,the MoSeTe/N,F@C anode exhibits high reversible capacities along with exceptional cycle stability.When coupled with Na_(3)V_(2)(PO_(4))_(3)@C(NVPF@C) to form SIB full cells,the anode delivers a reversible specific capacity of 126 mA h g^(-1) after 100 cycles at 0.1 A g^(-1).Furthermore,when combined with AC to form SIHC full cells,the anode demonstrates excellent cycling stability with a reversible specific capacity of50 mA h g^(-1) keeping over 3700 cycles at 1.0 A g^(-1).In situ XRD,ex situ TEM characterization,and theoretical calculations(DFT) further confirm the reversibility of sodium storage in MoSeTe/N,F@C anode materials during electrochemical reactions,highlighting their potential for widespread practical application.This work provides new insights into the promising utilization of advanced transition metal dichalcogenides as anode materials for Na^(+)-based energy storage devices.
基金supported by the National Natural Science Foundation of China (52102198)the Key R&D and Promotion Projects of Henan Province (212102310016)+1 种基金the Initial Scientific Research Fund of Ph.D.in Anyang Institute of Technology (BSJ2021043)the Initial Scientific Research Fund of Postdoctor in Anyang Institute of Technology (BHJ2022008)。
文摘Composite polymer electrolytes(CPEs)are considered to be the most promising to break through the performance and safety limitations of traditional lithium-ion batteries because of their excellent electrochemical and mechanical properties.Aiming at the performance limitations of the most common polyether matrix such as poly(ethylene oxide)(PEO),a novel poly(cyclocarbonate-ether)polymer matrix was prepared by in-situ thermal curing,the weaker interaction between its C=O bond and Li^(+)can promote the rapid transport of Li^(+).Adding ionic liquid and active filler LLZTO to the matrix can synergistically reduce the crystallinity of matrix and promote the dissociation of lithium salts.In addition,a 3D functional skeleton made of polyacrylonitrile(PAN)and lithium fluoride(LiF)can greatly improve the mechanical strength of polymer matrix after cold pressing,and Li F is also conducive to interface stability.The thickness of the optimal sample(VP6L/CPL)was only 25μm,and its ionic conductivity,lithium ion transference number,and electrochemical stability window were as high as 7.17×10^(-4)S cm^(-1)(25℃),0.54 and 5.4 V,respectively,while the mechanical strength reaches 6.1 MPa,which can fully inhibit the growth of lithium dendrites.The excellent electrochemical performance and mechanical strength enable the assembled Li|VP6L/CPL|Li battery to be continuously charged for over 200 h and cycled stably for more than 2300 h,and Li|VP6L/CPL|LFP battery can be stably cycled for more than 400 and 550 cycles at 1 C(40℃)and 0.5 C(25℃),respectively.
基金supported by the Science and Technology Funding from Jinan (grant number:2020GXRC018)the Academic Promotion Program of Shandong First Medical University (grant number:2019QL009)the Taishan Scholars Program of Shandong Province (grant number:TS201712065)。
文摘A growing number of studies have demonstrated that the skeleton is an endocrine organ that is involved in glucose metabolism and plays a significant role in human glucose homeostasis.However,there is still a limited understanding of the in vivo glucose uptake and distribution across the human skeleton.To address this issue,we aimed to elucidate the detailed profile of glucose uptake across the skeleton using a total-body positron emission tomography(PET)scanner.A total of 41 healthy participants were recruited.Two of them received a 1-hour dynamic total-body^(18)F-fluorodeoxyglucose(^(18)F-FDG)PET scan,and all of them received a10-minute static total-body^(18)F-FDG PET scan.The net influx rate(K_i)and standardized uptake value normalized by lean body mass(SUL)were calculated as indicators of glucose uptake from the dynamic and static PET data,respectively.The results showed that the vertebrae,hip bone and skull had relatively high Kiand SUL values compared with metabolic organs such as the liver.Both the K_(i) and SUL were higher in the epiphyseal,metaphyseal and cortical regions of long bones.Moreover,trends associated with age and overweight with glucose uptake(SUL_(max)and SUL_(mean))in bones were uncovered.Overall,these results indicate that the skeleton is a site with significant glucose uptake,and skeletal glucose uptake can be affected by age and dysregulated metabolism.
基金support from the National Natural Science Foundation of China[No.22075143,21875110]the Science Challenge Project[TZ2018004]the Qing Lan Project for the grant。
文摘In this study,a new energetic hybrid skeleton was constructed through the integration of nitropyrazole and 1,3,4-oxadiazole skeletons in a molecule.Furthermore,the energetic precursor(2),the azo-bridged compound(3),the neutral nitramine(4)and the corresponding energetic salts(5-7)were synthesized.Their physicochemical and energetic properties we re experimentally and theo retically evaluated.Among the developed compounds,the azo-bridged compound(3)and dihydroxylammoinium(6)display high detonation performances(3,D_(v)=8904 m/s,P=34.47 GPa;6,D_(v)=9025 m/s,P=34.66 GPa),moderate sensitivities(3,IS=16 J,FS=120 N;6,IS=20 J,FS=312 N)and good densities(3,1.87 g/cm^(3);6,1.81 g/cm^(3)),which indicates that they have the potential to replace the traditional high-energy explosive RDX.The results show that the integration of different energetic skeletons can achieve a good balance between energy and sensitivity.
基金support from the National Natural Science Foundation of China(Grant No.22075143,21875110)the Science Challenge Project(Grant No.TZ2018004)the Qing Lan Project for the grant。
文摘In light of the low yields and complex reaction routes of some well-known 5,5-fused and 5,6-fused bicyclic compounds,a series of 5,7-fused bicyclic imidazole-diazepine compounds were developed with high yields by only two efficient steps.Significantly,the seven-membered heterocyclic ring has a stable energetic skeleton with multiple modifiable sites.However,the 5,7-fused bicyclic energetic compounds were rarely reported in the area of energetic materials.Three neutral compounds 1,2 and 4 were synthesized in this work.To improve the detonation performances of the 5,7-fused neutral compounds,corresponding perchlorate 1a and 2a were further developed.The physicochemical and energetic performances of all newly developed compounds were experimentally determined.All newly prepared energetic compounds exhibit high decomposition temperatures(Td:243.8-336℃)and low mechanical sensitivities(IS:>15 J,FS:>280 N).Among them,the velocities performances of 1a(Dv=7651 m/s)and 4(Dv=7600 m/s)are comparable to that of typical heat-resistant energetic material HNS(Dv=7612 m/s).Meanwhile,the high decomposition temperature and low mechanical sensitivities(Td=336℃;IS=32 J;FS>353 N)of 4 are superior to that of HNS(Td=318℃;IS=5 J;FS=250 N).Hence,the 5,7-fused bicyclic compounds with high thermostability,low sensitivities and adjustable detonation performance have a clear tendency to open up a new space for the development of heat-resistant energetic materials.
基金financially supported by the National Natural Science Foundation of China (No.51874099)the National Science Foundation of Fujian Province’s Key Project,China (No.2021J02031)the support from the open fund from the Academy of Carbon Neutrality of Fujian Normal University,China (No.CZH2022-06)。
文摘To meet the low-cost concept advocated by the sodium metal anode,this paper reports the use of a pulsed electrodeposition technology with ionic liquids as electrolytes to achieve uniform nanoplating of metallic magnesium films at around 20 nm on spaced titanium dioxide(TiO_(2))nanotubes(STNA-Mg).First,the sodiophilic magnesium metal coating can effectively reduce the nucleation overpotential of sodium metal.Moreover,three-dimensional STNA can limit the volume expansion during sodium metal plating and stripping to achieve the ultrastable deposition and stripping of sodium metals with a high Coulombic efficiency of up to 99.5%and a small voltage polarization of 5 mV in symmetric Na||Na batteries.In addition,the comparative study of sodium metal deposition behavior of STNA-Mg and STNA-Cu prepared by the same route further confirmed the advantage of magnesium metal to guide sodium metal growth.Finally,the prepared STNA-Mg-Na metal anode and commercial sodium vanadium phosphate cathode were assembled into a full cell,delivering a discharge capacity of 110.2 mAh·g^(-1)with a retention rate of 95.6%after 110 cycles at 1C rate.
基金supported by the National Key R&D Program of China (2021ZD0202805,2019YFA0709504,2021ZD0200900)National Defense Science and Technology Innovation Special Zone Spark Project (20-163-00-TS-009-152-01)+4 种基金National Natural Science Foundation of China (31900719,U20A20227,82125008)Innovative Research Team of High-level Local Universities in Shanghai,Science and Technology Committee Rising-Star Program (19QA1401400)111 Project (B18015)Shanghai Municipal Science and Technology Major Project (2018SHZDZX01)Shanghai Center for Brain Science and Brain-Inspired Technology。
文摘Video-based action recognition is becoming a vital tool in clinical research and neuroscientific study for disorder detection and prediction.However,action recognition currently used in non-human primate(NHP)research relies heavily on intense manual labor and lacks standardized assessment.In this work,we established two standard benchmark datasets of NHPs in the laboratory:Monkeyin Lab(Mi L),which includes 13 categories of actions and postures,and MiL2D,which includes sequences of two-dimensional(2D)skeleton features.Furthermore,based on recent methodological advances in deep learning and skeleton visualization,we introduced the Monkey Monitor Kit(Mon Kit)toolbox for automatic action recognition,posture estimation,and identification of fine motor activity in monkeys.Using the datasets and Mon Kit,we evaluated the daily behaviors of wild-type cynomolgus monkeys within their home cages and experimental environments and compared these observations with the behaviors exhibited by cynomolgus monkeys possessing mutations in the MECP2 gene as a disease model of Rett syndrome(RTT).Mon Kit was used to assess motor function,stereotyped behaviors,and depressive phenotypes,with the outcomes compared with human manual detection.Mon Kit established consistent criteria for identifying behavior in NHPs with high accuracy and efficiency,thus providing a novel and comprehensive tool for assessing phenotypic behavior in monkeys.
基金supported by the National Nature Science Foundation of China under Grant No.52075340.
文摘Lattice structures with excellent physical properties have attracted great research interest.In this paper,a novel volume parametric modeling method based on the skeleton model is proposed for the construction of threedimensional lattice structures.The skeleton model is divided into three types of nodes.And the corresponding algorithms are utilized to construct diverse types of volume parametric nodes.The unit-cell is assembled with distinct nodes according to the geometric features.The final lattice structure is created by the periodic arrangement of unit-cells.Several different types of volume parametric lattice structures are constructed to prove the stability and applicability of the proposed method.The quality is assessed in terms of the value of the Jacobian matrix.Moreover,the volume parametric lattice structures are tested with the isogeometric analysis to verify the feasibility of integration of modeling and simulation.
基金the research grant of the National Natural Science Foundation of China(Grant No.52075125,No.52105331)The research was also partially supported by Shenzhen Science and Technology Innovation Committee(Grant No.JCYJ20210324124203009,No.JSGG20201102154600003,No.GXWD20220818163456002).
文摘The traditional nano-sintering or TLP techniques are generally expensive,time-consuming,and hence unsuitable for realizing practical mass production.Herein,we have developed an improved TLP process to rapidly produce IMC-skeleton structures across the bonding region by initiating a localized liquid-solid interaction among micron particles at traditional soldering temperatures.The developed IMC skeletons can reinforce solder alloys and provide remarkable mechanical stability and electrical capabilities at high temperatures.As a result,the IMC-skeleton strengthened interconnections exhibited higher thermal/electrical conductivity,lower hardness and almost doubled strength than traditional full-IMC joints,attaining 87.4 MPa and 30.2 MPa at room condition and 350℃.Meanwhile,the necessary heating time to form metallurgical bonds was shortened,one-fifth of nano-sintering and one-tenth of TLP bonding,and the material cost was significantly reduced.This proposed technique enabled the fast,low-cost manufacturing of electronics that can serve at temperatures as high as 200−350℃.Besides,the interfacial reactions among particles and the correlated phase evolution process were studied in this research.The formation mechanism of IMC skeletons was analyzed.The correlated influencing factors and their effect on the mechanical,thermal and electrical properties of joints were revealed,which may help the design and extensive uses of such techniques in various high-temperature/power applications.
基金the National Natural Science Foundation of China(No.61834005,61772417,61802304)the Shaanxi Province Key Research and Development Project(2021GY280).
文摘Compared with RGB videos and images,human bone data is less vulnerable to external factors and has stronger robustness.Therefore,behavior recognition methods based on skeletons are widely studied.Because graph convolution network(GCN)can deal with the irregular topology data of hu-man skeletons very well,more and more researchers apply GCN to human behavior recognition.Tra-ditional graph convolution methods only consider the joints with physical connectivity or the same type when building the behavior recognition model based on human skeletons structure,which cannot capture higher-order information better.To solve this problem,Motif-GCN is used in this paper to ex-tract spatial features.The relationship between the joints with natural connection in the human body is encoded by the first Motif-GCN,and the possible relationship between the unconnected joints in the human skeleton is encoded by the second Motif-GCN.In this way,the relationship between non-physical joints can be strengthened.Then a two stream framework combining joint and bone informa-tion is used to capture more action information.Finally,experiments are conducted on two subdata-sets X-Sub and X-View of NTU-RGB+D,and the accuracy shown in Top-1 classification results is 89.5%and 95.4%respectively.The experimental results are 1.0%and 0.3%higher than those of the 2S-AGCN model respectively.The superiority of this method is also proved by the experimental results.
基金supported by the National Natural Science Foundation of China(52072173)the Jiangsu Province Outstanding Youth Fund(BK20200016)the International Cooperation of Jiangsu Province(SBZ2022000084)
文摘Lithium metal batteries are emerging as a strong candidate in the future energy storage market due to its extremely high energy density.However,the uncontrollable lithium dendrites and volume change of lithium metal anodes severely hinder its application.In this work,the porous Cu skeleton modified with Cu_(6)Sn_(5)layer is prepared via dealloying brass foil following a facile electroless process.The porous Cu skeleton with large specific surface area and high electronic conductivity effectively reduces the local current density.The Cu_(6)Sn_(5)can react with lithium during the discharge process to form lithiophilic Li_(7)Sn_(2)in situ to promote Li-ions transport and reduce the nucleation energy barrier of lithium to guide the uniform lithium deposition.Therefore,more than 300 cycles at 1 mA cm^(−2)are achieved in the half-cell with an average Coulombic efficiency of 97.5%.The symmetric cell shows a superior cycle life of more than 1000 h at 1 mA cm^(−2)with a small average hysteresis voltage of 16 mV.When coupled with LiFePO_(4)cathode,the full cell also maintains excellent cycling and rate performance.
文摘Background: Off-pump coronary artery bypass grafting (OPCAB) is a surgical procedure that has gained popularity due to its potential benefits over traditional coronary artery bypass grafting, including reduced morbidity and mortality. However, sternal wound complication (SWC) remains challenging following the procedure. The technique of left internal mammary artery (LIMA) harvesting has been shown to impact the incidence of SWC. This study aimed to compare the incidence of SWC between two techniques of LIMA harvesting, i.e., skeletonized and pedicled. Methods: The study was conducted at the Department of Cardiac Surgery, Bangabandhu Sheikh Mujib Medical University, and included 60 patients who underwent OPCAB. The patients were divided into two groups of 30 each based on the technique of LIMA harvesting used, i.e., skeletonized (group A) or pedicled (group B). The postoperative ICU care was given to each patient as per the protocol. The statistical analysis was conducted using the SPSS version 26.0 for Windows software. Results: The results showed that 5 (8.33%) patients developed SWC, with 1 (1.67%) patient in group A and 4 (6.66%) patients in group B. However, the occurrence of SWC was not statistically significant between the two groups (p = 0.35). The mean age, gender distribution, and comorbidities such as hypertension, diabetes, dyslipidemia, and anemia were also not statistically significant between the two groups. The number of smokers was statistically significant between the two groups (p = 0.03), and the occurrence of SWC was found to be higher in smoker patients in group B (p = 0.04). Preoperative and postoperative parameters such as duration of operation, duration of mechanical ventilation, duration of chest drains, duration of the central venous line, and amount of postoperative mediastinal bleeding were also not statistically significant between the two groups. The distribution of wound complications, duration of ICU stays, and hospital stay between the two groups was also not statistically significant. Conclusion: In conclusion, this study found that the incidence of SWC was less in skeletonized LIMA harvesting than in pedicled LIMA harvesting after OPCAB. However, this finding was not statistically significant. Further studies with larger sample sizes may be needed to confirm these results and determine the appropriate technique of LIMA harvesting to decrease the incidence of SWC after OPCAB.
文摘Action recognition has been recognized as an activity in which individuals’behaviour can be observed.Assembling profiles of regular activities such as activities of daily living can support identifying trends in the data during critical events.A skeleton representation of the human body has been proven to be effective for this task.The skeletons are presented in graphs form-like.However,the topology of a graph is not structured like Euclideanbased data.Therefore,a new set of methods to perform the convolution operation upon the skeleton graph is proposed.Our proposal is based on the Spatial Temporal-Graph Convolutional Network(ST-GCN)framework.In this study,we proposed an improved set of label mapping methods for the ST-GCN framework.We introduce three split techniques(full distance split,connection split,and index split)as an alternative approach for the convolution operation.The experiments presented in this study have been trained using two benchmark datasets:NTU-RGB+D and Kinetics to evaluate the performance.Our results indicate that our split techniques outperform the previous partition strategies and aremore stable during training without using the edge importance weighting additional training parameter.Therefore,our proposal can provide a more realistic solution for real-time applications centred on daily living recognition systems activities for indoor environments.
