目的探讨术前年龄和NIHSS两者相结合的指标SPAN指数、wSPAN指数、SC评分对急性缺血性卒中(AIS)患者血管内治疗术后临床预后之间的关系。方法连续收集2015年8月—2021年10月就诊于中国3个综合性卒中中心接受血管内治疗的AIS患者889例,以...目的探讨术前年龄和NIHSS两者相结合的指标SPAN指数、wSPAN指数、SC评分对急性缺血性卒中(AIS)患者血管内治疗术后临床预后之间的关系。方法连续收集2015年8月—2021年10月就诊于中国3个综合性卒中中心接受血管内治疗的AIS患者889例,以门诊或电话方式随访90天。根据术后90天改良Rankin量表(90 d mRS)评分评估患者预后,分为预后良好组(mRS≤2分)和预后不良组(mRS>2分)。同时记录患者术后症状性颅内出血(sICH)、颅内出血转化的发生率及术后90天死亡率。结果在纳入的889例患者中,预后不良组血管内治疗前的SPAN指数、wSPAN指数、SC评分均显著高于预后良好组(P<0.001)。在调整潜在的混杂因素后,SPAN、wSPAN、SC均与EVT患者90天预后独立相关(SPAN:OR=0.961,95%CI=0.948-0.975、wSPAN:OR=0.968,95%CI=0.959-0.976、SC:OR=0.767,95%CI=0.713-0.826)。SPAN、wSPAN、SC与sICH之间没有统计学差异(P=0.220,P=0.088,P=0.072),而与颅内出血转化风险增加(SPAN:OR=1.03,95%CI=1.02-1.05,P<0.001、wSPAN:OR=1.03,95%CI=1.02-1.03,P<0.001、SC:OR=1.25,95%CI=1.14-1.36,P<0.001)和死亡率(P<0.001,P<0.001,P<0.001)相关。结论术前SPAN指数、wSPAN指数、SC评分与AIS患者血管内治疗90天临床预后、颅内出血转化发生率和高死亡率相关,但与sICH无关。展开更多
Introduction: Clinical assessment of hepatic span is usually subjective. And is based on the experience of the clinician. This is what has led to this study in using Biophysical profiling of Heights, Weights, and Body...Introduction: Clinical assessment of hepatic span is usually subjective. And is based on the experience of the clinician. This is what has led to this study in using Biophysical profiling of Heights, Weights, and Body mass index to find the normal hepatic span of every individual. This study was conducted at HMG Hospital Limited, Abonnema in Rivers State in affiliation with the University of Port Harcourt. Methodology: The biophysical sampling method was instituted to select respondents. At the same time, a radiological formula was used to calculate the sample size, and subjects’ weight, height and hepatic span where measured while the BMI was calculated and the data was analyzed using python programming language for data science. Results: The data obtained were subjected to descriptive statistics and the Pearson correlation coefficient. P value greater than or equal to 0.05 was taken as statistically significant. The respondents were mainly aged 30 to 63 years. Conclusion: The null hypothesis was rejected;hence this research has stated the law known as Belema’s Law of hepatic-height correlation, which states that the hepatic span of an individual is directly proportional to the height of that individual except in disease conditions affecting the liver directly or indirectly.展开更多
文摘目的探讨术前年龄和NIHSS两者相结合的指标SPAN指数、wSPAN指数、SC评分对急性缺血性卒中(AIS)患者血管内治疗术后临床预后之间的关系。方法连续收集2015年8月—2021年10月就诊于中国3个综合性卒中中心接受血管内治疗的AIS患者889例,以门诊或电话方式随访90天。根据术后90天改良Rankin量表(90 d mRS)评分评估患者预后,分为预后良好组(mRS≤2分)和预后不良组(mRS>2分)。同时记录患者术后症状性颅内出血(sICH)、颅内出血转化的发生率及术后90天死亡率。结果在纳入的889例患者中,预后不良组血管内治疗前的SPAN指数、wSPAN指数、SC评分均显著高于预后良好组(P<0.001)。在调整潜在的混杂因素后,SPAN、wSPAN、SC均与EVT患者90天预后独立相关(SPAN:OR=0.961,95%CI=0.948-0.975、wSPAN:OR=0.968,95%CI=0.959-0.976、SC:OR=0.767,95%CI=0.713-0.826)。SPAN、wSPAN、SC与sICH之间没有统计学差异(P=0.220,P=0.088,P=0.072),而与颅内出血转化风险增加(SPAN:OR=1.03,95%CI=1.02-1.05,P<0.001、wSPAN:OR=1.03,95%CI=1.02-1.03,P<0.001、SC:OR=1.25,95%CI=1.14-1.36,P<0.001)和死亡率(P<0.001,P<0.001,P<0.001)相关。结论术前SPAN指数、wSPAN指数、SC评分与AIS患者血管内治疗90天临床预后、颅内出血转化发生率和高死亡率相关,但与sICH无关。
文摘Introduction: Clinical assessment of hepatic span is usually subjective. And is based on the experience of the clinician. This is what has led to this study in using Biophysical profiling of Heights, Weights, and Body mass index to find the normal hepatic span of every individual. This study was conducted at HMG Hospital Limited, Abonnema in Rivers State in affiliation with the University of Port Harcourt. Methodology: The biophysical sampling method was instituted to select respondents. At the same time, a radiological formula was used to calculate the sample size, and subjects’ weight, height and hepatic span where measured while the BMI was calculated and the data was analyzed using python programming language for data science. Results: The data obtained were subjected to descriptive statistics and the Pearson correlation coefficient. P value greater than or equal to 0.05 was taken as statistically significant. The respondents were mainly aged 30 to 63 years. Conclusion: The null hypothesis was rejected;hence this research has stated the law known as Belema’s Law of hepatic-height correlation, which states that the hepatic span of an individual is directly proportional to the height of that individual except in disease conditions affecting the liver directly or indirectly.