目的:探讨甲状腺功能低下(甲低)及甲状腺功能亢进(甲亢)模型大鼠的甲状腺功能改变对血钙和血磷的影响。方法:制备甲低及甲亢大鼠模型,测定其血清T3、T4、TSH、钙、磷的含量变化。结果:甲低大鼠血清T3、T4和TSH浓度分别为0.27±0.08n...目的:探讨甲状腺功能低下(甲低)及甲状腺功能亢进(甲亢)模型大鼠的甲状腺功能改变对血钙和血磷的影响。方法:制备甲低及甲亢大鼠模型,测定其血清T3、T4、TSH、钙、磷的含量变化。结果:甲低大鼠血清T3、T4和TSH浓度分别为0.27±0.08nm o l/L、25.87±2.83nm o l/L和3.36±0.42mU/L,与对照组血清T3(0.97±0.11nm o l/L)和T4(68.74±7.57nm o l/L)相比较,均明显降低(P<0.0001),有极显著差异;而血清TSH较对照组TSH含量(1.72±0.43mU/L)显著升高(P<0.0001)。甲亢大鼠T3(9.24±1.56 nm o l/L)和T4(155.73±13.98nm o l/L)含量比对照组均显著升高(P<0.0001),而TSH含量仅为0.37±0.06mU/L,与对照组相比明显降低(P<0.0001)。对照组血钙(C a2+)和血磷(HPO42-)含量分别为2.37±0.30mm o l/L和2.56±0.10mm o l/L;甲低组血钙为2.27±0.15mm o l/L,血磷为2.33±0.10mm o l/L;甲亢组血钙含量为6.17±1.42mm o l/L,血磷含量为3.84±1.13mm o l/L。结论:甲亢大鼠血钙和血磷含量较正常大鼠明显升高。甲低大鼠血清钙、磷含量与对照组大鼠比较均有所下降,但无统计学意义。展开更多
After gun-shot wound with high velocity steel-ball pellet was inflicted of one hind limb ofthe pigs, the changes of hemodynamics, blood gases, chest x-ray films, serum T3 and T4,fibronectin, protein content of lung la...After gun-shot wound with high velocity steel-ball pellet was inflicted of one hind limb ofthe pigs, the changes of hemodynamics, blood gases, chest x-ray films, serum T3 and T4,fibronectin, protein content of lung lavage, lung weight, etc were observed within the 72-hour-peri-od postinjury or when the animal was killed or died 72 h postinjury. The pathological changes wereexamined as soon as possible with both optic and electron microscope. Changes of the above-men-tioned parameters in different intensity were found especially in those animals which diedspontaneously. In addition, the relationship between the occurrence of respiratory distresssyndrome(RDS) after trauma and the trauma index-injury severity score was discussed and it waspointed out that attention should be paid to the subclinical type of RDS.展开更多
文摘目的:探讨甲状腺功能低下(甲低)及甲状腺功能亢进(甲亢)模型大鼠的甲状腺功能改变对血钙和血磷的影响。方法:制备甲低及甲亢大鼠模型,测定其血清T3、T4、TSH、钙、磷的含量变化。结果:甲低大鼠血清T3、T4和TSH浓度分别为0.27±0.08nm o l/L、25.87±2.83nm o l/L和3.36±0.42mU/L,与对照组血清T3(0.97±0.11nm o l/L)和T4(68.74±7.57nm o l/L)相比较,均明显降低(P<0.0001),有极显著差异;而血清TSH较对照组TSH含量(1.72±0.43mU/L)显著升高(P<0.0001)。甲亢大鼠T3(9.24±1.56 nm o l/L)和T4(155.73±13.98nm o l/L)含量比对照组均显著升高(P<0.0001),而TSH含量仅为0.37±0.06mU/L,与对照组相比明显降低(P<0.0001)。对照组血钙(C a2+)和血磷(HPO42-)含量分别为2.37±0.30mm o l/L和2.56±0.10mm o l/L;甲低组血钙为2.27±0.15mm o l/L,血磷为2.33±0.10mm o l/L;甲亢组血钙含量为6.17±1.42mm o l/L,血磷含量为3.84±1.13mm o l/L。结论:甲亢大鼠血钙和血磷含量较正常大鼠明显升高。甲低大鼠血清钙、磷含量与对照组大鼠比较均有所下降,但无统计学意义。
文摘After gun-shot wound with high velocity steel-ball pellet was inflicted of one hind limb ofthe pigs, the changes of hemodynamics, blood gases, chest x-ray films, serum T3 and T4,fibronectin, protein content of lung lavage, lung weight, etc were observed within the 72-hour-peri-od postinjury or when the animal was killed or died 72 h postinjury. The pathological changes wereexamined as soon as possible with both optic and electron microscope. Changes of the above-men-tioned parameters in different intensity were found especially in those animals which diedspontaneously. In addition, the relationship between the occurrence of respiratory distresssyndrome(RDS) after trauma and the trauma index-injury severity score was discussed and it waspointed out that attention should be paid to the subclinical type of RDS.
