The editorial team of the International Journal of Nursing Sciences would like to thank our peer reviewers for all their support in 2022.It is based on the dedication and expertise of the editorial board and peer revi...The editorial team of the International Journal of Nursing Sciences would like to thank our peer reviewers for all their support in 2022.It is based on the dedication and expertise of the editorial board and peer reviewers to promote the academic quality and impact of the journal consistently.IJNSS will receive the first impact factor in 2023.If you would like to serve as a peer reviewer for the journal.展开更多
Objective THANK, known as a member of TNF superfamily,is a petent costimulator of both B and T lymphocytes and can promote a strong immune response.To investigate its role in liver immunotherapy,the anti-tumor effects...Objective THANK, known as a member of TNF superfamily,is a petent costimulator of both B and T lymphocytes and can promote a strong immune response.To investigate its role in liver immunotherapy,the anti-tumor effects of the THAND-transduced hepatoma cell line SMMU-7721 in vitro and in vivo studied. Methods THANK full-elngth cDNA was transfected into SMMU-7721 cell line .The transfectant with stable expression of THAND was obtained by clone selection and THANK's effects on hepatoma cells were analyzed,further the tumorigenicity of THANK -transduced 7721 cells was examined in nude mice.Results THANK's expression in 7721 cells inhibited the growth of hepatoma cells and induced a strong CTL response in vitro.The cell cycle analysis showed that THANK transfected 7721 cells were arrested in the S phase.The expression of THANK in SMMU-7721 cell line not only inhibited the tumorigenicity of 7721 cells,but also induced a systemic immune response against re-chalenge of parental 7721 tumors. Conclusion THANK transduction in SMMU-7721 cells can induce an effective immune response in nude mice and may be useful for the immunotherapy of hepatomas.展开更多
<正>A person may meet many challenges in his or her life.Some people think challenges are terrible.But I think they’re great.And I want to say,'Thank you,challenges!'For some people,it’s hard to face t...<正>A person may meet many challenges in his or her life.Some people think challenges are terrible.But I think they’re great.And I want to say,'Thank you,challenges!'For some people,it’s hard to face the challenges because they are afraid of failing in the end.However,it’s necessary for a person to face the challenges.Challenges are good to~①you.展开更多
According to the Thomson Reuter report on 20 June 2013,the 2012 Impact Factor of Journal of Natural Gas Chemistry,renamed as Journal of Energy Chemistry in 2013,is 1.405,which ranks first among chemistry journals in C...According to the Thomson Reuter report on 20 June 2013,the 2012 Impact Factor of Journal of Natural Gas Chemistry,renamed as Journal of Energy Chemistry in 2013,is 1.405,which ranks first among chemistry journals in China.We would like to express our appreciation to all the authors who have contributed their good work to the Journal.The following is the list of the articles published in 2010 and 2011which received the most citations and thus contributed the most to the new impact factor.展开更多
The editorial staff of the Hepatobiliary&Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the
The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listedreviewers for their contributions to the improvement of the manuscripts received and the publication
The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the j...The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the journal in the year of 2007.展开更多
The editorial staff of the Hepatobiliary&Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication
文摘The editorial team of the International Journal of Nursing Sciences would like to thank our peer reviewers for all their support in 2022.It is based on the dedication and expertise of the editorial board and peer reviewers to promote the academic quality and impact of the journal consistently.IJNSS will receive the first impact factor in 2023.If you would like to serve as a peer reviewer for the journal.
文摘Objective THANK, known as a member of TNF superfamily,is a petent costimulator of both B and T lymphocytes and can promote a strong immune response.To investigate its role in liver immunotherapy,the anti-tumor effects of the THAND-transduced hepatoma cell line SMMU-7721 in vitro and in vivo studied. Methods THANK full-elngth cDNA was transfected into SMMU-7721 cell line .The transfectant with stable expression of THAND was obtained by clone selection and THANK's effects on hepatoma cells were analyzed,further the tumorigenicity of THANK -transduced 7721 cells was examined in nude mice.Results THANK's expression in 7721 cells inhibited the growth of hepatoma cells and induced a strong CTL response in vitro.The cell cycle analysis showed that THANK transfected 7721 cells were arrested in the S phase.The expression of THANK in SMMU-7721 cell line not only inhibited the tumorigenicity of 7721 cells,but also induced a systemic immune response against re-chalenge of parental 7721 tumors. Conclusion THANK transduction in SMMU-7721 cells can induce an effective immune response in nude mice and may be useful for the immunotherapy of hepatomas.
文摘<正>A person may meet many challenges in his or her life.Some people think challenges are terrible.But I think they’re great.And I want to say,'Thank you,challenges!'For some people,it’s hard to face the challenges because they are afraid of failing in the end.However,it’s necessary for a person to face the challenges.Challenges are good to~①you.
文摘According to the Thomson Reuter report on 20 June 2013,the 2012 Impact Factor of Journal of Natural Gas Chemistry,renamed as Journal of Energy Chemistry in 2013,is 1.405,which ranks first among chemistry journals in China.We would like to express our appreciation to all the authors who have contributed their good work to the Journal.The following is the list of the articles published in 2010 and 2011which received the most citations and thus contributed the most to the new impact factor.
文摘The editorial staff of the Hepatobiliary&Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the
文摘The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listedreviewers for their contributions to the improvement of the manuscripts received and the publication
文摘The editorial staff of the Hepatobiliary & Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication of the journal in the year of 2007.
文摘The editorial staff of the Hepatobiliary&Pancreatic Diseases International are grateful to the listed reviewers for their contributions to the improvement of the manuscripts received and the publication
