【目的】比较不同剂量右美托咪定抑制喉部肿瘤手术气管切开插管诱发应激反应的效果。【方法】拟在全麻下限期行喉部肿瘤手术的患者120例，年龄40～60岁，ASAⅠ或Ⅱ级，喉阻塞Ⅰ～Ⅱ度，随机分为四组，每组30例：对照组（C组）、低、中...【目的】比较不同剂量右美托咪定抑制喉部肿瘤手术气管切开插管诱发应激反应的效果。【方法】拟在全麻下限期行喉部肿瘤手术的患者120例，年龄40～60岁，ASAⅠ或Ⅱ级，喉阻塞Ⅰ～Ⅱ度，随机分为四组，每组30例：对照组（C组）、低、中、高剂量右美托咪定（D1～3组）。分别在气管切开插管前15 m in静脉注射15 mL生理盐水、右美托咪定02．5、05．、07．5μg／kg ，输注时间15 min。之后局麻下行气管切开插管，全麻诱导，机械通气。记录输注右美托咪定前（T0）、插管前即刻（T1）、插管成功即刻（T2）、麻醉诱导后3 min（T3）患者的心率（HR）、血压（BP）、脉搏血氧饱和度（SpO2）及气管切开插管过程中患者高血压、心动过速、体动、呛咳、呼吸抑制等不良反应事件。术后随访测评两组患者气管切开插管过程中的痛苦程度，进行舒适满意度评价。【结果】与T0时比较，C组和D1组收缩压（SBP）、舒张压（DBP）、HR在 T1～2时升高（ P ＜00．5）；T3时C组和D1～2组SBP、DBP、HR降低，D3组SBP和DBP升高（ P ＜00．5）。T1～2时，C组和D1组SBP、DBP、HR明显高于D2组（ P ＜00．1）。T1～3时D3组较D2组SBP和DBP升高（ P ＜00．5）。D2组患者高血压、心动过速、体动、呛咳等不良反应事件的发生明显减少，D2组舒适满意度高于C组和D1组。所有患者均未发生呼吸抑制。【结论】静脉输注右美托咪定达05．μg／kg时，可显著抑制伤害性刺激诱发的不良应激反应，且无明显呼吸抑制。展开更多
The wireless fieldbus is a vital part in present industrial automatic controls and software-defined systems. Accompanying, security is an upcoming problem determines its future leapfrog development. Wireless fieldbus ...The wireless fieldbus is a vital part in present industrial automatic controls and software-defined systems. Accompanying, security is an upcoming problem determines its future leapfrog development. Wireless fieldbus systems can be made secure by encrypting the data. Unfortunately, the diffusion character of encryption brings significant vulnerabilities in terms of deteriorated error performance and energy efficiency. In this paper, we first propose an AES-dependent Hsiao(AD-Hsiao) code to improve the error correction capability, which leverages the prior information of data similarity and AES decryption to assist syndrome decoding. Then, we develop "Random Coset" scheme to reduce energy consumption. Based on mapping written data into several data candidates, this scheme lessens the number of bits written to memory and thereby boosts the write energy efficiency. Simulation results show that the AD-Hsiao code can correct majority of double errors in a single codeword with limited latency and area cost as the Hamming code. Moreover, the(72,64) AD-Hsiao code improves the reliability by 102 over the(72,64) Hamming code at 8 dB AWGN channel, and also exceeding the high cost(78,64) BCH code. In addition, the "Random Coset" improves energy efficiency by 6.6～14% than the current scheme while re-quires small ROM storage.展开更多
文摘【目的】比较不同剂量右美托咪定抑制喉部肿瘤手术气管切开插管诱发应激反应的效果。【方法】拟在全麻下限期行喉部肿瘤手术的患者120例，年龄40～60岁，ASAⅠ或Ⅱ级，喉阻塞Ⅰ～Ⅱ度，随机分为四组，每组30例：对照组（C组）、低、中、高剂量右美托咪定（D1～3组）。分别在气管切开插管前15 m in静脉注射15 mL生理盐水、右美托咪定02．5、05．、07．5μg／kg ，输注时间15 min。之后局麻下行气管切开插管，全麻诱导，机械通气。记录输注右美托咪定前（T0）、插管前即刻（T1）、插管成功即刻（T2）、麻醉诱导后3 min（T3）患者的心率（HR）、血压（BP）、脉搏血氧饱和度（SpO2）及气管切开插管过程中患者高血压、心动过速、体动、呛咳、呼吸抑制等不良反应事件。术后随访测评两组患者气管切开插管过程中的痛苦程度，进行舒适满意度评价。【结果】与T0时比较，C组和D1组收缩压（SBP）、舒张压（DBP）、HR在 T1～2时升高（ P ＜00．5）；T3时C组和D1～2组SBP、DBP、HR降低，D3组SBP和DBP升高（ P ＜00．5）。T1～2时，C组和D1组SBP、DBP、HR明显高于D2组（ P ＜00．1）。T1～3时D3组较D2组SBP和DBP升高（ P ＜00．5）。D2组患者高血压、心动过速、体动、呛咳等不良反应事件的发生明显减少，D2组舒适满意度高于C组和D1组。所有患者均未发生呼吸抑制。【结论】静脉输注右美托咪定达05．μg／kg时，可显著抑制伤害性刺激诱发的不良应激反应，且无明显呼吸抑制。
基金supported by the National Natural Science Foundation of China (NSFC, 91538202, 91338103)the new strategic industries development projects of Shenzhen City (JCYJ20160520140157342,CXZZ20150928165834560)
文摘The wireless fieldbus is a vital part in present industrial automatic controls and software-defined systems. Accompanying, security is an upcoming problem determines its future leapfrog development. Wireless fieldbus systems can be made secure by encrypting the data. Unfortunately, the diffusion character of encryption brings significant vulnerabilities in terms of deteriorated error performance and energy efficiency. In this paper, we first propose an AES-dependent Hsiao(AD-Hsiao) code to improve the error correction capability, which leverages the prior information of data similarity and AES decryption to assist syndrome decoding. Then, we develop "Random Coset" scheme to reduce energy consumption. Based on mapping written data into several data candidates, this scheme lessens the number of bits written to memory and thereby boosts the write energy efficiency. Simulation results show that the AD-Hsiao code can correct majority of double errors in a single codeword with limited latency and area cost as the Hamming code. Moreover, the(72,64) AD-Hsiao code improves the reliability by 102 over the(72,64) Hamming code at 8 dB AWGN channel, and also exceeding the high cost(78,64) BCH code. In addition, the "Random Coset" improves energy efficiency by 6.6～14% than the current scheme while re-quires small ROM storage.
