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Viscoacoustic prestack reverse time migration based onthe optimal time-space domain high-order finite-difference method 被引量:7
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作者 赵岩 刘洋 任志明 《Applied Geophysics》 SCIE CSCD 2014年第1期50-62,116,共14页
Prestack reverse time migration (RTM) is an accurate imaging method ofsubsurface media. The viscoacoustic prestack RTM is of practical significance because itconsiders the viscosity of the subsurface media. One of t... Prestack reverse time migration (RTM) is an accurate imaging method ofsubsurface media. The viscoacoustic prestack RTM is of practical significance because itconsiders the viscosity of the subsurface media. One of the steps of RTM is solving thewave equation and extrapolating the wave field forward and backward; therefore, solvingaccurately and efficiently the wave equation affects the imaging results and the efficiencyof RTM. In this study, we use the optimal time-space domain dispersion high-order finite-difference (FD) method to solve the viscoacoustic wave equation. Dispersion analysis andnumerical simulations show that the optimal time-space domain FD method is more accurateand suppresses the numerical dispersion. We use hybrid absorbing boundary conditions tohandle the boundary reflection. We also use source-normalized cross-correlation imagingconditions for migration and apply Laplace filtering to remove the low-frequency noise.Numerical modeling suggests that the viscoacoustic wave equation RTM has higher imagingresolution than the acoustic wave equation RTM when the viscosity of the subsurface isconsidered. In addition, for the wave field extrapolation, we use the adaptive variable-lengthFD operator to calculate the spatial derivatives and improve the computational efficiencywithout compromising the accuracy of the numerical solution. 展开更多
关键词 REVERSE time migration Viscoacoustic Optimization Adaptive time-spacedomain FINITE-DIFFERENCE
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Earthquake-Affected Time-Space Domain, Recurrence Interval and Effective Preparation Time of Earthquakes
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作者 Wang Shengzu and Zhang ZongchunInstitute of Geology & Laboratory of Tectonophysics, China Seismological Bureau, Beijing 100029, China 《Earthquake Research in China》 2002年第4期380-395,共16页
The study shows that earthquake-affected time-space domain (ETSD), i.e. a time-space range in which strong earthquakes are unable to occur owing to the influence of a prior earthquake occurring, shows a hyperbolic mar... The study shows that earthquake-affected time-space domain (ETSD), i.e. a time-space range in which strong earthquakes are unable to occur owing to the influence of a prior earthquake occurring, shows a hyperbolic margin curve in the t(time)-r(distance) coordinate plane, which has a maximum affected radius r 0 at t=0 and a maximum influence time t 0 (i.e. the in-situ recurrence interval of earthquakes) at r=0. Based on the time-distance distributions of posterior earthquakes relative to prior ones in the regions of North China, Northwest China, Qinghai-Xizang (Tibet) plateau and Southwest China, the optimized and 90%-confidence margin curves are estimated using optimization and statistical analysis methods. This indicates that the concept and method of ETSD with 3-dimension (time-distance-magnitudes) instead of those of “recurrence interval" with 1-dimension (time) or 2-dimension (time-magnitude) provides a new approach to understanding the fluctuation of seismic activities, estimating the effective earthquake-preparation time of potential hypocenters, and therefore improving the medium- and long-term prediction of strong earthquakes. 展开更多
关键词 Earthquake-affected time-space domain Recurrence interval Affected radius Effective earthquake-preparation time
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Modeling of Surface Waves in a Fluid Saturated Poro-Elastic Medium under Initial Stress Using Time-Space Domain Higher Order Finite Difference Method
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作者 Anjana P. Ghorai R. Tiwary 《Applied Mathematics》 2013年第3期469-476,共8页
In this present context, mathematical modeling of the propagation of surface waves in a fluid saturated poro-elastic medium under the influence of initial stress has been considered using time dependent higher order f... In this present context, mathematical modeling of the propagation of surface waves in a fluid saturated poro-elastic medium under the influence of initial stress has been considered using time dependent higher order finite difference method (FDM). We have proved that the accuracy of this finite-difference scheme is 2M when we use 2nd order time domain finite-difference and 2M-th order space domain finite-difference. It also has been shown that the dispersion curves of Love waves are less dispersed for higher order FDM than of lower order FDM. The effect of initial stress, porosity and anisotropy of the layer in the propagation of Love waves has been studied here. The numerical results have been shown graphically. As a particular case, the phase velocity in a non porous elastic solid layer derived in this paper is in perfect agreement with that of Liu et al. (2009). 展开更多
关键词 LOVE WAVES FLUID Saturated Initially Stressed POROUS Layer time-space domain Finite DIFFERENCE Scheme Accuracy Dispersion Analysis Phase Velocity
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A time-space network-based model for transportation service optimization of China Railway Express
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作者 Weichuan Yin Wenhu Hu +2 位作者 Xueting Yan Bo Peng Xiaoling Yang 《High-Speed Railway》 2024年第3期153-163,共11页
This paper describes the development and optimization plans for the China Railway Express(CR Express).As a new type of international land transport organization,CR Express has emerged with the continuous expansion of ... This paper describes the development and optimization plans for the China Railway Express(CR Express).As a new type of international land transport organization,CR Express has emerged with the continuous expansion of China toward European investment and trade,and in particular,has expanded with the continuous progress of the One Belt and One Road(OBOR)initiative.In addition to improving the service quality of CR Express,the operating costs must be reduced for developing“smart railways”that serve“smart cities”.We propose a dualobjective-based function mathematical optimization model;the satisfaction of the cargo owner is considered,and the timeliness,transportation capacity,and goods category constraints of CR Express transportation are designed.Moreover,we present the normalized equivalent method of the two-objective function of the model.Finally,a case study is conducted against the background of certain trains in the western corridor of CR Express to validate the effectiveness of the model and research methods proposed in this study. 展开更多
关键词 One Belt and One Road China Railway Express Transportation service Mathematical optimization time-space network
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Finite Difference Schemes for Time-Space Fractional Diffusion Equations in One-and Two-Dimensions
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作者 Yu Wang Min Cai 《Communications on Applied Mathematics and Computation》 EI 2023年第4期1674-1696,共23页
In this paper,finite difference schemes for solving time-space fractional diffusion equations in one dimension and two dimensions are proposed.The temporal derivative is in the Caputo-Hadamard sense for both cases.The... In this paper,finite difference schemes for solving time-space fractional diffusion equations in one dimension and two dimensions are proposed.The temporal derivative is in the Caputo-Hadamard sense for both cases.The spatial derivative for the one-dimensional equation is of Riesz definition and the two-dimensional spatial derivative is given by the fractional Laplacian.The schemes are proved to be unconditionally stable and convergent.The numerical results are in line with the theoretical analysis. 展开更多
关键词 time-space fractional diffusion equation Caputo-Hadamard derivative Riesz derivative Fractional Laplacian Numerical analysis
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Delineating homogeneous domains of fractured rocks using topological manifolds and deep learning
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作者 Yongqiang Liu Jianping Chen +3 位作者 Fujun Zhou Jiewei Zhan Wanglai Xu Jianhua Yan 《Journal of Rock Mechanics and Geotechnical Engineering》 SCIE CSCD 2024年第8期2996-3013,共18页
Determining homogeneous domains statistically is helpful for engineering geological modeling and rock mass stability evaluation.In this text,a technique that can integrate lithology,geotechnical and structural informa... Determining homogeneous domains statistically is helpful for engineering geological modeling and rock mass stability evaluation.In this text,a technique that can integrate lithology,geotechnical and structural information is proposed to delineate homogeneous domains.This technique is then applied to a high and steep slope along a road.First,geological and geotechnical domains were described based on lithology,faults,and shear zones.Next,topological manifolds were used to eliminate the incompatibility between orientations and other parameters(i.e.trace length and roughness)so that the data concerning various properties of each discontinuity can be matched and characterized in the same Euclidean space.Thus,the influence of implicit combined effect in between parameter sequences on the homogeneous domains could be considered.Deep learning technique was employed to quantify abstract features of the characterization images of discontinuity properties,and to assess the similarity of rock mass structures.The results show that the technique can effectively distinguish structural variations and outperform conventional methods.It can handle multisource engineering geological information and multiple discontinuity parameters.This technique can also minimize the interference of human factors and delineate homogeneous domains based on orientations or multi-parameter with arbitrary distributions to satisfy different engineering requirements. 展开更多
关键词 Homogeneous domain Geological domain Geotechnical domain Structural domain Topological manifold Deep learning
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Consistency between domain wall oscillation modes and spin wave modes in nanostrips
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作者 董新伟 吴振江 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第6期511-516,共6页
Investigations on domain wall(DW) and spin wave(SW) modes in a series of nanostrips with different widths and thicknesses have been carried out using micromagnetic simulation. The simulation results show that the freq... Investigations on domain wall(DW) and spin wave(SW) modes in a series of nanostrips with different widths and thicknesses have been carried out using micromagnetic simulation. The simulation results show that the frequencies of SW modes and the corresponding DW modes are consistent with each other if they have the same node number along the width direction. This consistency is more pronounced in wide and thin nanostrips, favoring the DW motion driven by SWs.Further analysis of the moving behavior of a DW driven by SWs is also carried out. The average DW speed can reach a larger value of ~ 140 m/s under two different SW sources. We argue that this study is very meaningful for the potential application of DW motion driven by SWs. 展开更多
关键词 micromagnetic simulation domain wall spin wave
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Mapping the antiparallel aligned domain rotation by microwave excitation
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作者 Jing Zhang Yuanzhi Cui +11 位作者 Xiaoyu Wang Chuang Wang Mengchen Liu Jie Xu Kai Li Yunhe Zhao Zhenyan Lu Lining Pan Chendong Jin Qingfang Liu Jianbo Wang Derang Cao 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第9期599-605,共7页
The evolution process of magnetic domains in response to external fields is crucial for the modern understanding and application of spintronics.In this study,we investigated the domain rotation in stripe domain films ... The evolution process of magnetic domains in response to external fields is crucial for the modern understanding and application of spintronics.In this study,we investigated the domain rotation in stripe domain films of varying thicknesses by examining their response to microwave excitation in four different orientations.The resonance spectra indicate that the rotation field of stripe domain film under an applied magnetic field approaches the field where the resonance mode of sample changes.The saturation field of the stripe domain film corresponds to the field where the resonance mode disappears when measured in the stripe direction parallel to the microwave magnetic field.The results are reproducible and consistent with micromagnetic simulations,providing additional approaches and techniques for comprehending the microscopic mechanisms of magnetic domains and characterizing their rotation. 展开更多
关键词 stripe domain magnetic film microwave excitation micromagnetic simulation
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Low-Rank Optimal Transport for Robust Domain Adaptation
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作者 Bingrong Xu Jianhua Yin +2 位作者 Cheng Lian Yixin Su Zhigang Zeng 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第7期1667-1680,共14页
When encountering the distribution shift between the source(training) and target(test) domains, domain adaptation attempts to adjust the classifiers to be capable of dealing with different domains. Previous domain ada... When encountering the distribution shift between the source(training) and target(test) domains, domain adaptation attempts to adjust the classifiers to be capable of dealing with different domains. Previous domain adaptation research has achieved a lot of success both in theory and practice under the assumption that all the examples in the source domain are welllabeled and of high quality. However, the methods consistently lose robustness in noisy settings where data from the source domain have corrupted labels or features which is common in reality. Therefore, robust domain adaptation has been introduced to deal with such problems. In this paper, we attempt to solve two interrelated problems with robust domain adaptation:distribution shift across domains and sample noises of the source domain. To disentangle these challenges, an optimal transport approach with low-rank constraints is applied to guide the domain adaptation model training process to avoid noisy information influence. For the domain shift problem, the optimal transport mechanism can learn the joint data representations between the source and target domains using a measurement of discrepancy and preserve the discriminative information. The rank constraint on the transport matrix can help recover the corrupted subspace structures and eliminate the noise to some extent when dealing with corrupted source data. The solution to this relaxed and regularized optimal transport framework is a convex optimization problem that can be solved using the Augmented Lagrange Multiplier method, whose convergence can be mathematically proved. The effectiveness of the proposed method is evaluated through extensive experiments on both synthetic and real-world datasets. 展开更多
关键词 domain adaptation low-rank constraint noise corruption optimal transport
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Multiple Matching Attenuation Based on Curvelet Domain Extended Filtering
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作者 HUA Qingfeng CHEN Zhang +6 位作者 HE Huili TAN Jun CHEN Haifeng LI Guanbao SONG Peng ZHAO Bo JIANG Xiuping 《Journal of Ocean University of China》 SCIE CAS CSCD 2024年第4期924-932,共9页
The paper develops a multiple matching attenuation method based on extended filtering in the curvelet domain,which combines the traditional Wiener filtering method with the matching attenuation method in curvelet doma... The paper develops a multiple matching attenuation method based on extended filtering in the curvelet domain,which combines the traditional Wiener filtering method with the matching attenuation method in curvelet domain.Firstly,the method uses the predicted multiple data to generate the Hilbert transform records,time derivative records and time derivative records of Hilbert transform.Then,the above records are transformed into the curvelet domain and multiple matching attenuation based on least squares extended filtering is performed.Finally,the attenuation results are transformed back into the time-space domain.Tests on the model data and field data show that the method proposed in the paper effectively suppress the multiples while preserving the primaries well.Furthermore,it has higher accuracy in eliminating multiple reflections,which is more suitable for the multiple attenuation tasks in the areas with complex structures compared to the time-space domain extended filtering method and the conventional curvelet transform method. 展开更多
关键词 multiple matching attenuation curvelet domain extended filtering
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BIG HANKEL OPERATORS ON HARDY SPACES OF STRONGLY PSEUDOCONVEX DOMAINS
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作者 陈伯勇 江良英 《Acta Mathematica Scientia》 SCIE CSCD 2024年第3期789-809,共21页
In this article,we investigate the(big) Hankel operator H_(f) on the Hardy spaces of bounded strongly pseudoconvex domains Ω in C^(n).We observe that H_(f ) is bounded on H~p(Ω)(1 <p <∞) if f belongs to BMO a... In this article,we investigate the(big) Hankel operator H_(f) on the Hardy spaces of bounded strongly pseudoconvex domains Ω in C^(n).We observe that H_(f ) is bounded on H~p(Ω)(1 <p <∞) if f belongs to BMO and we obtain some characterizations for Hf on H^(2)(Ω) of other pseudoconvex domains.In these arguments,Amar's L^(p)-estimations and Berndtsson's L^(2)-estimations for solutions of the ■_(b)-equation play a crucial role.In addition,we solve Gleason's problem for Hardy spaces H^(p)(Ω)(1 ≤p≤∞) of bounded strongly pseudoconvex domains. 展开更多
关键词 Hankel operator Hardy space Bergman space pseudoconvex domain
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Complementary-Label Adversarial Domain Adaptation Fault Diagnosis Network under Time-Varying Rotational Speed and Weakly-Supervised Conditions
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作者 Siyuan Liu Jinying Huang +2 位作者 Jiancheng Ma Licheng Jing Yuxuan Wang 《Computers, Materials & Continua》 SCIE EI 2024年第4期761-777,共17页
Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems,such as relatively ideal speed conditions and sample conditions.In engineering practice,the rotational speed of the mac... Recent research in cross-domain intelligence fault diagnosis of machinery still has some problems,such as relatively ideal speed conditions and sample conditions.In engineering practice,the rotational speed of the machine is often transient and time-varying,which makes the sample annotation increasingly expensive.Meanwhile,the number of samples collected from different health states is often unbalanced.To deal with the above challenges,a complementary-label(CL)adversarial domain adaptation fault diagnosis network(CLADAN)is proposed under time-varying rotational speed and weakly-supervised conditions.In the weakly supervised learning condition,machine prior information is used for sample annotation via cost-friendly complementary label learning.A diagnosticmodel learning strategywith discretized category probabilities is designed to avoidmulti-peak distribution of prediction results.In adversarial training process,we developed virtual adversarial regularization(VAR)strategy,which further enhances the robustness of the model by adding adversarial perturbations in the target domain.Comparative experiments on two case studies validated the superior performance of the proposed method. 展开更多
关键词 Time-varying rotational speed weakly-supervised fault diagnosis domain adaptation
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ON THE SOBOLEV DOLBEAULT COHOMOLOGY OF A DOMAIN WITH PSEUDOCONCAVE BOUNDARIES
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作者 陈健 《Acta Mathematica Scientia》 SCIE CSCD 2024年第2期431-444,共14页
In this note,we mainly make use of a method devised by Shaw[15]for studying Sobolev Dolbeault cohomologies of a pseudoconcave domain of the type Ω=Ω\∪_(j=1^(m))Ω_(j),where Ω and {Ω_(j)}_(j=1^(m)■Ω are bounded ... In this note,we mainly make use of a method devised by Shaw[15]for studying Sobolev Dolbeault cohomologies of a pseudoconcave domain of the type Ω=Ω\∪_(j=1^(m))Ω_(j),where Ω and {Ω_(j)}_(j=1^(m)■Ω are bounded pseudoconvex domains in ℂ^(n) with smooth boundaries,and Ω_(1),…,Ω_(m) are mutually disjoint.The main results can also be quickly obtained by virtue of[5]. 展开更多
关键词 Cauchy-Riemann equations pseudoconcave domains δ-Neumann operator Bergman spaces
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Diabetic retinopathy identification based on multi-sourcefree domain adaptation
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作者 Guang-Hua Zhang Guang-Ping Zhuo +3 位作者 Zhao-Xia Zhang Bin Sun Wei-Hua Yang Shao-Chong Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第7期1193-1204,共12页
AIM:To address the challenges of data labeling difficulties,data privacy,and necessary large amount of labeled data for deep learning methods in diabetic retinopathy(DR)identification,the aim of this study is to devel... AIM:To address the challenges of data labeling difficulties,data privacy,and necessary large amount of labeled data for deep learning methods in diabetic retinopathy(DR)identification,the aim of this study is to develop a source-free domain adaptation(SFDA)method for efficient and effective DR identification from unlabeled data.METHODS:A multi-SFDA method was proposed for DR identification.This method integrates multiple source models,which are trained from the same source domain,to generate synthetic pseudo labels for the unlabeled target domain.Besides,a softmax-consistence minimization term is utilized to minimize the intra-class distances between the source and target domains and maximize the inter-class distances.Validation is performed using three color fundus photograph datasets(APTOS2019,DDR,and EyePACS).RESULTS:The proposed model was evaluated and provided promising results with respectively 0.8917 and 0.9795 F1-scores on referable and normal/abnormal DR identification tasks.It demonstrated effective DR identification through minimizing intra-class distances and maximizing inter-class distances between source and target domains.CONCLUSION:The multi-SFDA method provides an effective approach to overcome the challenges in DR identification.The method not only addresses difficulties in data labeling and privacy issues,but also reduces the need for large amounts of labeled data required by deep learning methods,making it a practical tool for early detection and preservation of vision in diabetic patients. 展开更多
关键词 diabetic retinopathy multisource-free domain adaptation pseudo-label generation softmaxconsistence minimization
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Magnetic domain structures in ultrathin Bi_(2)Te_(3)/CrTe_(2) heterostructures
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作者 夏体瑞 杨笑天 +6 位作者 张逸凡 刘馨琪 蔡新雨 刘畅 姚岐 寇煦丰 王文波 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第8期511-517,共7页
Chromium tellurium compounds are important two-dimensional van der Waals ferromagnetic materials with high Curie temperature and chemical stability in air,which is promising for applications in spintronic devices.Here... Chromium tellurium compounds are important two-dimensional van der Waals ferromagnetic materials with high Curie temperature and chemical stability in air,which is promising for applications in spintronic devices.Here,highquality spin-orbital-torque(SOT)device,Bi_(2)Te_(3)/CrTe_(2)heterostructure was epitaxially grown on Al_(2)O_(3)(0001)substrates.Anomalous Hall measurements indicate the existence of strong ferromagnetism in this device with the CrTe_(2)thickness down to 10 nm.In order to investigate its micromagnetic structure,cryogenic magnetic force microscope(MFM)was utilized to measure the magnetic domain evolutions at various temperatures and magnetic fields.The virgin domain state of the device shows a worm-like magnetic domain structure with the size around 0.6μm-0.8μm.Larger irregular-shape magnetic domains(>1μm)can be induced and pinned,after the field is increased to coercive field and ramped back to low fields.The temperature-dependent MFM signals exhibit a nice mean-field-like ferromagnetic transition with Curie temperature around 201.5 K,indicating a robust ferromagnetic ordering.Such a device can be potentially implemented in future magnetic memory technology. 展开更多
关键词 CrTe_(2) magnetic domain magnetic force microscopy
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MINIMIZERS OF L^(2)-SUBCRITICAL VARIATIONAL PROBLEMS WITH SPATIALLY DECAYING NONLINEARITIES IN BOUNDED DOMAINS
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作者 陈彬 高永帅 +1 位作者 郭玉劲 吴越 《Acta Mathematica Scientia》 SCIE CSCD 2024年第3期984-996,共13页
This paper is concerned with the minimizers of L^(2)-subcritical constraint variar tional problems with spatially decaying nonlinearities in a bounded domain Ω of R~N(N≥1).We prove that the problem admits minimizers... This paper is concerned with the minimizers of L^(2)-subcritical constraint variar tional problems with spatially decaying nonlinearities in a bounded domain Ω of R~N(N≥1).We prove that the problem admits minimizers for any M> 0.Moreover,the limiting behavior of minimizers as M→∞ is also analyzed rigorously. 展开更多
关键词 decaying nonlinearity L~2-subcritical MINIMIZERS bounded domains mass concentration
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Spatial correlations in time and frequency domains between chlorophyll-a concentration and environmental factors in the Bohai Sea
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作者 Wan XU Di MU +1 位作者 Zhenteng YANG Dekui YUAN 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2024年第4期1143-1156,共14页
Based on the reconstructed MODIS data and ECMWF reanalysis data from 2003 to 2021,spatial correlations between chlorophyll a(Chl a)and sea surface temperature(SST),photosynthetically available radiation(PAR),aerosol o... Based on the reconstructed MODIS data and ECMWF reanalysis data from 2003 to 2021,spatial correlations between chlorophyll a(Chl a)and sea surface temperature(SST),photosynthetically available radiation(PAR),aerosol optical thickness(AOT),and wind speed(WS)in the Bohai Sea were analyzed from the perspective of time domain and frequency domain.Results indicate that the frequency domain analysis was more conducive to revealing the correlations between Chl a and environmental factors.The spatial pattern of time-domain correlations was similar to the isobaths of the Bohai Sea,which was positive in shallow waters and negative in deep waters for SST,PAR,and AOT,and was reversed for WS.Frequency-domain correlations were obtained by performing Fourier Transform and were higher than correlations in time domain.The spatial distributions indicated that the effects of SST and PAR on Chl a were greater than AOT and WS in the Bohai Sea.Additionally,cross-spectrum analysis was applied to explore the response relationships.A depth-dependent pattern was shown in correlations and time lags,indicating that the influential mechanism of environmental factors on Chl-a concentration is related to seawater depth. 展开更多
关键词 chlorophyll a(Chl a) frequency domain spatial correlation Bohai Sea
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A Time-Domain Numerical Simulation for Free Motion Responses of Two Ships Advancing in Head Waves
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作者 PAN Su-yong CHENG Yong 《China Ocean Engineering》 SCIE EI CSCD 2024年第3期519-530,共12页
The constant panel method within the framework of potential flow theory in the time domain is developed for solving the hydrodynamic interactions between two parallel ships with forward speed.When solving problems wit... The constant panel method within the framework of potential flow theory in the time domain is developed for solving the hydrodynamic interactions between two parallel ships with forward speed.When solving problems within a time domain framework,the free water surface needs to simultaneously satisfy both the kinematic and dynamic boundary conditions of the free water surface.This provides conditions for adding artificial damping layers.Using the Runge−Kutta method to solve equations related to time.An upwind differential scheme is used in the present method to deal with the convection terms on the free surface to prevent waves upstream.Through the comparison with the available experimental data and other numerical methods,the present method is proved to have good mesh convergence,and satisfactory results can be obtained.The constant panel method is applied to calculate the hydrodynamic interaction responses of two parallel ships advancing in head waves.Numerical simulations are conducted on the effects of forward speed,different longitudinal and lateral distances on the motion response of two modified Wigley ships in head waves.Then further investigations are conducted on the effects of different ship types on the motion response. 展开更多
关键词 ship motions time domain simulation forward speed different distances wave loads
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Targeting neuronal PAS domain protein 2 and KN motif/ankyrin repeat domains 1:Advances in type 2 diabetes therapy
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作者 Chun-Han Cheng Wen-Rui Hao Tzu-Hurng Cheng 《World Journal of Diabetes》 SCIE 2024年第11期2173-2176,共4页
This editorial summarizes the latest literature on the roles of neuronal PAS domain protein 2 and KN motif/ankyrin repeat domain 1 in type 2 diabetes(T2D).We highlight their involvement inβ-cell dysfunction,explore t... This editorial summarizes the latest literature on the roles of neuronal PAS domain protein 2 and KN motif/ankyrin repeat domain 1 in type 2 diabetes(T2D).We highlight their involvement inβ-cell dysfunction,explore their potential as therapeutic targets,and discuss the implications for new treatment strategies.We offer valuable insights into relevant gene regulation and cellular mechanisms relevant for the targeted management of T2D. 展开更多
关键词 Type 2 diabetes Neuronal PAS domain protein 2 KN motif and ankyrin repeat domain 1 β-cell dysfunction Therapeutic target
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