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Tonopen-XL和tonopen-AVIA眼压计在C57BL6小鼠眼压测量的相关研究
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作者 张曙光 李燕 +2 位作者 何跃 袁授生 马林昆 《中国保健营养(下半月)》 2010年第4期31-32,共2页
目的通过TON0PEN-XL与T0N0PEN—AVIA两种非侵袭性眼压计在不同时间测量实验小鼠眼压的比较,以评价其相关性和差异性。方法取正常C57BL/6小鼠20只,在清醒状态下,分别在同一天的不同时间点测量右眼眼压,每周至少测量3天,共观察4周... 目的通过TON0PEN-XL与T0N0PEN—AVIA两种非侵袭性眼压计在不同时间测量实验小鼠眼压的比较,以评价其相关性和差异性。方法取正常C57BL/6小鼠20只,在清醒状态下,分别在同一天的不同时间点测量右眼眼压,每周至少测量3天,共观察4周。结果TONOPEN—XL在上午10点的测量结果为957±2.34mmHg,下午3点为7.93±1.15mmHg晚上9点为8.21±147mmHg,三个时间点的眼压测量无显著差异;TONOPEN-AVIA在上午10点为1435±158mmHg,下午3点为14±1.24mmHg,晚上9点为1405±1.01mmHg。三个时间点的眼压测量无显著差异;Tonopen-XL的测量结果低于tonopen—AVIA的测量结果,两者相比有统计学差异。结论TonoPen—XL的眼压测量低于tonopen—AVfA的眼压测量结果,且两者之间缺乏相关性。 展开更多
关键词 tonopen-XL tonopen—AVIA 眼压测量 小鼠
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Proview 眼压监测仪、Goldmann压平眼压计及TonoPen眼压计的临床比较
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作者 汪玲 Li J +1 位作者 Herndon L.W Asrani S.G 《世界核心医学期刊文摘(眼科学分册)》 2005年第1期26-27,共2页
Objective:To compare intraocular p ressure(IOP)values obtained by patients using the new Pr oview eye pressure monitor(Bausch &Lomb,Rochester,NY)with those measured with the Goldmann tonomete r and the TonoPen(Men... Objective:To compare intraocular p ressure(IOP)values obtained by patients using the new Pr oview eye pressure monitor(Bausch &Lomb,Rochester,NY)with those measured with the Goldmann tonomete r and the TonoPen(Mentor,Norwell,Mass).Methods:Eighty-six patients(a total of 171eyes)-with a diagnosis of glaucoma or glaucoma suspect successfully comp leted the study.The IOP was measured by 3methods in the fo llowing order:Goldmann tonometer,TonoPen,and Pr oview eye pressure monitor.The central corneal thickn ess was measured by an ultrasonic pachymeter.Separate ly for each eye,the differences in mean IOP values betwe en measurement methods were assessed with paired te sts and also in mul-tivariate models that tested the dep endence of IOP differ-ence on central corneal thickness.R esults:There was a significant difference(P<.001)in the mean IOPs measured by the 3different methods(Goldmann vs Proview,Goldmann vs TonoPen,and TonoPen vs Proview)for both eyes,and the difference was indepen-dent of the central corneal thickness.The differences be-tween IOP measured by Goldmann and Pr oview were sim-ilar in all categories of patient-re ported ease of using the Proview.Conclusions:The IOPs obta ined with the Proview eye pressure monitor are sig nificantly lower than those measured with Goldmann tonome ter and the TonoPen,and variations of the centr al corneal thickness do not contribute to the difference.Intraclass correlations of IOP values obtained with the Goldm ann and the Proview or TonoPen and Proview are not strong.On the other hand,as expected,measurements with Goldmann and TonoPen agreed fairly well. 展开更多
关键词 压平眼压计 GOLDMANN Proview tonopen 监测仪 眼压值 中央角膜厚度 角膜中央厚度 超声厚度计 有显著性差异
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应用Tono-pen眼压计测量正常人24 h眼压的临床研究 被引量:3
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作者 张金顺 彭寿雄 +2 位作者 林明楷 方爱武 杜驰 《眼视光学杂志》 2006年第4期233-235,共3页
目的研究正常人24h眼压的变动规律。方法选择年龄为30~60岁的正常志愿者30人(60眼),应用Tono-pen眼压计进行24h的眼压测量。测量自清晨7:00开始至第二天清晨7:00,每2h测一次眼压,共测12次。在7:00—23:00时间段中,测受检者... 目的研究正常人24h眼压的变动规律。方法选择年龄为30~60岁的正常志愿者30人(60眼),应用Tono-pen眼压计进行24h的眼压测量。测量自清晨7:00开始至第二天清晨7:00,每2h测一次眼压,共测12次。在7:00—23:00时间段中,测受检者的坐位眼压和卧位眼压。在23:00—07:00时间段,测受检者的平卧位眼压。结果志愿者眼压高峰出现在1:30,眼压低谷出现在17:30,24h坐、卧位眼压变动幅度大于24h卧位眼压变动幅度。结论正常人的眼压高峰大多出现在夜间睡眠时间,测受检者的坐、卧位眼压是一种较好的24h眼压测量方法。 展开更多
关键词 眼内压 体位 昼夜变动节律 Tono—pen眼压计
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