We investigate the Floquet spectrum and excitation properties of a two-ultracold-atom system with periodically driven interaction in a three-dimensional harmonic trap.The interaction between the atoms is changed by va...We investigate the Floquet spectrum and excitation properties of a two-ultracold-atom system with periodically driven interaction in a three-dimensional harmonic trap.The interaction between the atoms is changed by varying the s-wave scattering length in two ways,the cosine and the square-wave modulations.It is found that as the driving frequency increases,the Floquet spectrum exhibits two main features for both modulations,the accumulating and the spreading of the quasienergy levels,which further lead to different dynamical behaviors.The accumulation is associated with collective excitations and the persistent growth of the energy,while the spread indicates that the energy is bounded at all times.The initial scattering length,the driving frequency and amplitude can all significantly change the Floquet spectrum as well as the dynamics.However,the corresponding relation between them is valid universally.Finally,we propose a mechanism for selectively exciting the system to one specific state by using the avoided crossing of two quasienergy levels,which could guide preparation of a desired state in experiments.展开更多
Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal cha...Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal characteristics and contextual information compared to 3D CT blocks.However,3D CT blocks necessitate significantly higher hardware resources during the learning phase.Therefore,efficiently exploiting temporal correlation and spatial-temporal features of 2D CT slices is crucial for ULD tasks.In this paper,we propose a ULD network with the enhanced temporal correlation for this purpose,named TCE-Net.The designed TCE module is applied to enrich the discriminate feature representation of multiple sequential CT slices.Besides,we employ multi-scale feature maps to facilitate the localization and detection of lesions in various sizes.Extensive experiments are conducted on the DeepLesion benchmark demonstrate that thismethod achieves 66.84%and 78.18%for FS@0.5 and FS@1.0,respectively,outperforming compared state-of-the-art methods.展开更多
Many patients have achieved a favorable overall survival rate since allogenic hematopoietic stem cell transplantation(allo-HSCT)has been widely implemented to treat hematologic malignancies.However,graft-versus-host d...Many patients have achieved a favorable overall survival rate since allogenic hematopoietic stem cell transplantation(allo-HSCT)has been widely implemented to treat hematologic malignancies.However,graft-versus-host disease(GVHD)and complications of immunosuppressive drugs after allo-HSCT are the main causes of non-relapse mortality and a poor quality of life.In addition,GVHD and infusion-induced toxicity still occur with donor lymphocyte infusions(DLIs)and chimeric antigen receptor(CAR)T-cell therapy.Because of the special immune tolerance characteristics and anti-tumor ability of universal immune cells,universal immune cell therapy may strongly reduce GVHD,while simultaneously reducing tumor burden.Nevertheless,widespread application of universal immune cell therapy is mainly restricted by poor expansion and persistence efficacy.Many strategies have been applied to improve universal immune cell proliferation and persistence efficacy,including the use of universal cell lines,signaling regulation and CAR technology.In this review we have summarized current advances in universal immune cell therapy for hematologic malignancies with a discussion of future perspectives.展开更多
Lithium(Li)metal electrodes show significantly different reversibility in the electrolytes with different salts.However,the understanding on how the salts impact on the Li loss remains unclear.Herein,using the electro...Lithium(Li)metal electrodes show significantly different reversibility in the electrolytes with different salts.However,the understanding on how the salts impact on the Li loss remains unclear.Herein,using the electrolytes with different salts(e.g.,lithium hexafluorophosphate(LiPF_(6)),lithium difluoro(oxalato)borate(LiDFOB),and lithium bis(fluorosulfonyl)amide(LiFSI))as examples,we decouple the irreversible Li loss(SEI Li^(+)and“dead”Li)during cycling.It is found that the accumulation of both SEI Li^(+)and“dead”Li may be responsible to the irreversible Li loss for the Li metal in the electrolyte with LiPF_(6)salt.While for the electrolytes with LiDFOB and LiFSI salts,the accumulation of“dead”Li predominates the Li loss.We also demonstrate that lithium nitrate and fluoroethylene carbonate additives could,respectively,function as the“dead”Li and SEI Li^(+)inhibitors.Inspired by the above understandings,we propose a universal procedure for the electrolyte design of Li metal batteries(LMBs):(i)decouple and find the main reason for the irreversible Li loss;(ii)add the corresponding electrolyte additive.With such a Li-loss-targeted strategy,the Li reversibility was significantly enhanced in the electrolytes with 1,2-dimethoxyethane,triethyl phosphate,and tetrahydrofuran solvents.Our strategy may broaden the scope of electrolyte design toward practical LMBs.展开更多
For pseudocapacitive electrode materials(PseEMs),despite much progress having been made in achieving both high power density and high energy density,a general strategy to guide the enhancement of intrinsic capacitive ...For pseudocapacitive electrode materials(PseEMs),despite much progress having been made in achieving both high power density and high energy density,a general strategy to guide the enhancement of intrinsic capacitive properties of PseEMs remains lacking.Here,we demonstrate a universal chargecompensating strategy to improve the charge-storage capability of PseEMs intrinsically:ⅰ) in the electrolyte with anion as charge carriers(such as OH-),reducing the multivalent cations of PseEMs into lower valences could create more reversible low-to-high valence redox cou ples to promote the intercalation of the anions;ⅱ) in the electrolytes with cation as charge carriers(such as H^(+),Li^(+),Na^(+)),oxidizing the multivalent cations of PseEMs into higher valences could introduce more reversible high-to-low valence redox couples to promote the intercalation of the cations.And we demonstrated that the improved intrinsic charge-storage capability for PseEMs originates from the increased Faradaic charge storage sites.展开更多
Recently,deep learning has achieved remarkable results in fields that require human cognitive ability,learning ability,and reasoning ability.Activation functions are very important because they provide the ability of ...Recently,deep learning has achieved remarkable results in fields that require human cognitive ability,learning ability,and reasoning ability.Activation functions are very important because they provide the ability of artificial neural networks to learn complex patterns through nonlinearity.Various activation functions are being studied to solve problems such as vanishing gradients and dying nodes that may occur in the deep learning process.However,it takes a lot of time and effort for researchers to use the existing activation function in their research.Therefore,in this paper,we propose a universal activation function(UA)so that researchers can easily create and apply various activation functions and improve the performance of neural networks.UA can generate new types of activation functions as well as functions like traditional activation functions by properly adjusting three hyperparameters.The famous Convolutional Neural Network(CNN)and benchmark datasetwere used to evaluate the experimental performance of the UA proposed in this study.We compared the performance of the artificial neural network to which the traditional activation function is applied and the artificial neural network to which theUA is applied.In addition,we evaluated the performance of the new activation function generated by adjusting the hyperparameters of theUA.The experimental performance evaluation results showed that the classification performance of CNNs improved by up to 5%through the UA,although most of them showed similar performance to the traditional activation function.展开更多
The geometric characteristics of fractures within a rock mass can be inferred by the data sampling from boreholes or exposed surfaces.Recently,the universal elliptical disc(UED)model was developed to represent natural...The geometric characteristics of fractures within a rock mass can be inferred by the data sampling from boreholes or exposed surfaces.Recently,the universal elliptical disc(UED)model was developed to represent natural fractures,where the fracture is assumed to be an elliptical disc and the fracture orientation,rotation angle,length of the long axis and ratio of short-long axis lengths are considered as variables.This paper aims to estimate the fracture size-and azimuth-related parameters in the UED model based on the trace information from sampling windows.The stereological relationship between the trace length,size-and azimuth-related parameters of the UED model was established,and the formulae of the mean value and standard deviation of trace length were proposed.The proposed formulae were validated via the Monte Carlo simulations with less than 5%of error rate between the calculated and true values.With respect to the estimation of the size-and azimuth-related parameters using the trace length,an optimization method was developed based on the pre-assumed size and azimuth distribution forms.A hypothetical case study was designed to illustrate and verify the parameter estimation method,where three combinations of the sampling windows were used to estimate the parameters,and the results showed that the estimated values could agree well with the true values.Furthermore,a hypothetical three-dimensional(3D)elliptical fracture network was constructed,and the circular disc,non-UED and UED models were used to represent it.The simulated trace information from different models was compared,and the results clearly illustrated the superiority of the proposed UED model over the existing circular disc and non-UED models。展开更多
Somalia is a country facing numerous challenges in achieving universal health coverage (UHC) and ensuring adequate healthcare financing, This article explores the complexities and obstacles that Somalia must overcome ...Somalia is a country facing numerous challenges in achieving universal health coverage (UHC) and ensuring adequate healthcare financing, This article explores the complexities and obstacles that Somalia must overcome in its pursuit of UHC, the paper begins by providing an overview of the current healthcare landscape in Somalia, highlighting the lack of infrastructure, political instability, and limited financial resources that hinder the establishment of a comprehensive and equitable healthcare system. It then examines the role of international aid and non-governmental organizations (NGOs) in filling the healthcare gap, while emphasizing the need for a more sustainable, domestically financed solution. Drawing on a range of data sources and case studies, the article proposes a multi-faceted approach to strengthen healthcare governance, improve resource allocation, and foster local capacity building, the study delves into the unique obstacles that Somalia faces, including a lack of infrastructure, political instability, and limited financial resources, which hinder the establishment of a comprehensive and equitable healthcare system. The paper also examines the role of international aid and non-governmental organizations (NGOs) in filling the healthcare gap, while highlighting the need for a more sustainable, domestically financed solution. The findings underscore the importance of political commitment, international cooperation, and innovative financing mechanisms in advancing towards UHC in Somalia, providing valuable insights for other low resource, conflict affected settings.展开更多
Recent research indicates that black holes can grow based on the expansion of the universe and not just through accretion and mergers. Two different models independently predicted that finding. One model, describing t...Recent research indicates that black holes can grow based on the expansion of the universe and not just through accretion and mergers. Two different models independently predicted that finding. One model, describing the relevant massive star remnants as “generic objects of dark energy”, rejects the traditional view of black holes while hypothesizing that dark energy causes the cosmologically coupled growth of these objects. The other model, based on the probabilistic spacetime theory, indicates the growth of black holes is based on the same spacetime mechanism underlying all universal expansion, and does so while leaving the traditional black hole conceptualization essentially intact. The fact these two models predicted this observational finding but did so from different perspectives suggests more can be learned by further study of their differences. This paper explores similarities and differences in the two models’ explanations for massive star remnants’ growth, concluding with suggestions for research testing their relative veracity. An exploration of the relative utility and parsimony of the two models is also described.展开更多
Introduction: The launch of health insurance in the Republic of the Congo took place against a backdrop of extremely high costs for dialysis, which was not one of the services financed within this framework. The aim o...Introduction: The launch of health insurance in the Republic of the Congo took place against a backdrop of extremely high costs for dialysis, which was not one of the services financed within this framework. The aim of this study is to assess the impact of including dialysis in the health insurance package in Congo. Methodology: This is a descriptive cross-sectional study with an evaluative aim, analyzing the impact of dialysis on the financing capacity of health insurance and health facilities to provide this type of care. Results: The results show that including dialysis in the universal health insurance package will require an additional financial effort of 6.20% of the current total financing capacity of the care basket. Most dialysis sessions are provided by the private health sector (87.5%), whose health facilities are unevenly distributed across the country, and concentrated in the country’s two major cities. This problem is the dual consequence of the very high cost of a dialysis session (average cost 140,234,375 FCFA or 229 US Dollars) and the number of patients under care, which will increase in the absence of effective and ongoing prevention efforts against chronic diseases in general and end-stage renal failure in particular. Conclusion: Dialysis is a high-impact public health intervention. The impact of its inclusion in the universal health insurance care package is difficult to bear financially. For dialysis to be covered by universal health insurance, additional funding and improved technical facilities are needed.展开更多
In this work, we show that it is possible to establish coordinate transformations between inertial reference frames in the theory of special relativity with a minimum universal speed of physical transmissions. The est...In this work, we show that it is possible to establish coordinate transformations between inertial reference frames in the theory of special relativity with a minimum universal speed of physical transmissions. The established coordinate transformations, referred to as modified Lorentz transformations because they have almost identical form to the Lorentz transformations, also comply with the requirement of invariance of the Minkowski line element. Particularly, the minimum universal speed can be associated with the phase speed of de Broglie matter wave. As application, we also discuss the possibility to formulate relativistic classical and quantum mechanics for the special relativity associated with the modified Lorentz transformations, which describes physical processes that represent an expansion or a collapsing of massive quantum particles.展开更多
In the example of formulating the Universal Declara-tion of Human Rights in 1948,which involved international human rights discourse,the“cross-cultural consensus”put forward based on Confucian culture by Zhang pengc...In the example of formulating the Universal Declara-tion of Human Rights in 1948,which involved international human rights discourse,the“cross-cultural consensus”put forward based on Confucian culture by Zhang pengchun,the Chinese representative at that time,is widely considered an empirical reference for resolving confrontations and conflicts in the practice of human rights discourse.However,the effectiveness of this kind of cross-cultural consensus in addressing confrontations and conflicts is worth considering.Under the presumption of cultural differences,any attempt to resolve confrontations and conflicts in the human rights discourse must address the inherently controversial issues.the settlement of disputes and differences depends on how deep the consensus involves the values.Based on this,it reveals that the effectiveness of Zhang pengchun’s so-called contribution is limited.therefore,we should not overstate its relevance to the current human rights discourse.展开更多
Results of analytical studies of the physical properties of the function and number of empirical macrohardness based on the standard experimental force diagram of kinetic macroindentation by a sphere.An analytical com...Results of analytical studies of the physical properties of the function and number of empirical macrohardness based on the standard experimental force diagram of kinetic macroindentation by a sphere.An analytical comparison method and a criterion for the similarity of the physical and empirical macrohardness of a material are proposed.The physical properties of the hardness measurement process using the Calvert-Johnson method are shown.The physical reasons for the size effect when measuring macrohardness are considered.The universal physical unit and standard of macrohardness of kinetic macroindentation by a sphere is substantiated.展开更多
In the present paper, an efficient algorithm based on the continued fractions theory was established for the universal Y’s functions of space dynamics. The algorithm is valid for any conic motion (elliptic, parabolic...In the present paper, an efficient algorithm based on the continued fractions theory was established for the universal Y’s functions of space dynamics. The algorithm is valid for any conic motion (elliptic, parabolic or hyperbolic).展开更多
What and how we translate are questions often argued about. No matter what kind of answers one may give, priority in translation should be granted to meaning, especially those meanings that exist in all concerned lang...What and how we translate are questions often argued about. No matter what kind of answers one may give, priority in translation should be granted to meaning, especially those meanings that exist in all concerned languages. This research defines them as universal sememes, and the study of them as universal semantics, of which applications are also briefly looked into.展开更多
目的:探究观察3M Single Bond Universal粘接系统对前牙E-max铸瓷贴面修复的远期疗效。方法:选择2017年5月-2019年5月笔者医院收治的需前牙E-max铸瓷贴面修复患者63例(患牙113颗)为研究对象,均行经典贴面修复,根据粘接系统的不同将患者...目的:探究观察3M Single Bond Universal粘接系统对前牙E-max铸瓷贴面修复的远期疗效。方法:选择2017年5月-2019年5月笔者医院收治的需前牙E-max铸瓷贴面修复患者63例(患牙113颗)为研究对象,均行经典贴面修复,根据粘接系统的不同将患者分为观察组(患者21例,患牙40颗,采用3M Single Bond Universal粘接系统)、对照1组(患者21例,患牙36颗,采用VariolinkⅡ粘接系统)、对照2组(患者21例,患牙37颗,采用BISCO CHOICE 2粘接系统)。治疗后三组均于1周、3个月、12个月时进行随访,观察三组治疗后1周、3个月、12个月内贴面修复效果、贴面修复失败率及不良反应发生率。结果:术后1周,三组患者均无失败案例;对照1组存在2颗修复体保存完整度为Ⅰ级的患牙,对照2组存在3颗修复体保存完整度为I级的患牙,观察组未存在该类患者;术后12个月,观察组存在1颗修复体保存完整度Ⅱ级患牙,对照1组存在1颗保存完整度I级患牙,3颗修复体保存完整度Ⅱ级患牙,对照2组存在2颗保存完整度I级患牙,3颗修复体保存完整度Ⅱ级患牙。三组患者治疗效果比较,差异无统计学意义(P>0.05);术后1周、3个月、12个月三组贴面修复失败率比较,差异无统计学意义(P>0.05);随访期间内,三组患者不良反应情况比较差异均无统计学意义(P>0.05)。结论:对于前牙E-max铸瓷贴面修复患者,选取合适的适应证,并做好备牙步骤,3M Single Bond Universal与经典VariolinkⅡ粘接系统及BISCO CHOICE 2粘接系统治疗效果并无显著差异,值得在临床推广使用。展开更多
基金supported by the National Natural Science Foundation of China(Grant No.12004049)the Fund of State Key Laboratory of IPOC(BUPT)(Grant Nos.600119525 and 505019124).
文摘We investigate the Floquet spectrum and excitation properties of a two-ultracold-atom system with periodically driven interaction in a three-dimensional harmonic trap.The interaction between the atoms is changed by varying the s-wave scattering length in two ways,the cosine and the square-wave modulations.It is found that as the driving frequency increases,the Floquet spectrum exhibits two main features for both modulations,the accumulating and the spreading of the quasienergy levels,which further lead to different dynamical behaviors.The accumulation is associated with collective excitations and the persistent growth of the energy,while the spread indicates that the energy is bounded at all times.The initial scattering length,the driving frequency and amplitude can all significantly change the Floquet spectrum as well as the dynamics.However,the corresponding relation between them is valid universally.Finally,we propose a mechanism for selectively exciting the system to one specific state by using the avoided crossing of two quasienergy levels,which could guide preparation of a desired state in experiments.
基金Taishan Young Scholars Program of Shandong Province,Key Development Program for Basic Research of Shandong Province(ZR2020ZD44).
文摘Universal lesion detection(ULD)methods for computed tomography(CT)images play a vital role in the modern clinical medicine and intelligent automation.It is well known that single 2D CT slices lack spatial-temporal characteristics and contextual information compared to 3D CT blocks.However,3D CT blocks necessitate significantly higher hardware resources during the learning phase.Therefore,efficiently exploiting temporal correlation and spatial-temporal features of 2D CT slices is crucial for ULD tasks.In this paper,we propose a ULD network with the enhanced temporal correlation for this purpose,named TCE-Net.The designed TCE module is applied to enrich the discriminate feature representation of multiple sequential CT slices.Besides,we employ multi-scale feature maps to facilitate the localization and detection of lesions in various sizes.Extensive experiments are conducted on the DeepLesion benchmark demonstrate that thismethod achieves 66.84%and 78.18%for FS@0.5 and FS@1.0,respectively,outperforming compared state-of-the-art methods.
基金supported by the National Key R&D Program of China(Grant No.2022YFA1103300)the National Natural Science Foundation of China(Grant No.82020108004)+3 种基金the Natural Science Foundation of Chongqing Innovation Group Science Program(Grant No.cstc2021jcyjcxttX0001)the Natural Science Foundation of Chongqing(Grant No.CSTB2022NSCQ-MSX1060)the Special Project for Talent Construction in Xinqiao Hospital(Grant No.2022XKRC001)the National College Student Innovation and Entrepreneurship Training Program(Grant No.202190035001).
文摘Many patients have achieved a favorable overall survival rate since allogenic hematopoietic stem cell transplantation(allo-HSCT)has been widely implemented to treat hematologic malignancies.However,graft-versus-host disease(GVHD)and complications of immunosuppressive drugs after allo-HSCT are the main causes of non-relapse mortality and a poor quality of life.In addition,GVHD and infusion-induced toxicity still occur with donor lymphocyte infusions(DLIs)and chimeric antigen receptor(CAR)T-cell therapy.Because of the special immune tolerance characteristics and anti-tumor ability of universal immune cells,universal immune cell therapy may strongly reduce GVHD,while simultaneously reducing tumor burden.Nevertheless,widespread application of universal immune cell therapy is mainly restricted by poor expansion and persistence efficacy.Many strategies have been applied to improve universal immune cell proliferation and persistence efficacy,including the use of universal cell lines,signaling regulation and CAR technology.In this review we have summarized current advances in universal immune cell therapy for hematologic malignancies with a discussion of future perspectives.
基金This work was supported by the National Key Research and Development Program(2021YFB2400300)the National Natural Science Foundation of China(52272203)the Fundamental Research Funds for the Central Universities(2021GCRC001).
文摘Lithium(Li)metal electrodes show significantly different reversibility in the electrolytes with different salts.However,the understanding on how the salts impact on the Li loss remains unclear.Herein,using the electrolytes with different salts(e.g.,lithium hexafluorophosphate(LiPF_(6)),lithium difluoro(oxalato)borate(LiDFOB),and lithium bis(fluorosulfonyl)amide(LiFSI))as examples,we decouple the irreversible Li loss(SEI Li^(+)and“dead”Li)during cycling.It is found that the accumulation of both SEI Li^(+)and“dead”Li may be responsible to the irreversible Li loss for the Li metal in the electrolyte with LiPF_(6)salt.While for the electrolytes with LiDFOB and LiFSI salts,the accumulation of“dead”Li predominates the Li loss.We also demonstrate that lithium nitrate and fluoroethylene carbonate additives could,respectively,function as the“dead”Li and SEI Li^(+)inhibitors.Inspired by the above understandings,we propose a universal procedure for the electrolyte design of Li metal batteries(LMBs):(i)decouple and find the main reason for the irreversible Li loss;(ii)add the corresponding electrolyte additive.With such a Li-loss-targeted strategy,the Li reversibility was significantly enhanced in the electrolytes with 1,2-dimethoxyethane,triethyl phosphate,and tetrahydrofuran solvents.Our strategy may broaden the scope of electrolyte design toward practical LMBs.
基金supported by the National Natural Science Foundation of China(51972146,52072150)。
文摘For pseudocapacitive electrode materials(PseEMs),despite much progress having been made in achieving both high power density and high energy density,a general strategy to guide the enhancement of intrinsic capacitive properties of PseEMs remains lacking.Here,we demonstrate a universal chargecompensating strategy to improve the charge-storage capability of PseEMs intrinsically:ⅰ) in the electrolyte with anion as charge carriers(such as OH-),reducing the multivalent cations of PseEMs into lower valences could create more reversible low-to-high valence redox cou ples to promote the intercalation of the anions;ⅱ) in the electrolytes with cation as charge carriers(such as H^(+),Li^(+),Na^(+)),oxidizing the multivalent cations of PseEMs into higher valences could introduce more reversible high-to-low valence redox couples to promote the intercalation of the cations.And we demonstrated that the improved intrinsic charge-storage capability for PseEMs originates from the increased Faradaic charge storage sites.
基金This work was supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2022R1F1A1062953).
文摘Recently,deep learning has achieved remarkable results in fields that require human cognitive ability,learning ability,and reasoning ability.Activation functions are very important because they provide the ability of artificial neural networks to learn complex patterns through nonlinearity.Various activation functions are being studied to solve problems such as vanishing gradients and dying nodes that may occur in the deep learning process.However,it takes a lot of time and effort for researchers to use the existing activation function in their research.Therefore,in this paper,we propose a universal activation function(UA)so that researchers can easily create and apply various activation functions and improve the performance of neural networks.UA can generate new types of activation functions as well as functions like traditional activation functions by properly adjusting three hyperparameters.The famous Convolutional Neural Network(CNN)and benchmark datasetwere used to evaluate the experimental performance of the UA proposed in this study.We compared the performance of the artificial neural network to which the traditional activation function is applied and the artificial neural network to which theUA is applied.In addition,we evaluated the performance of the new activation function generated by adjusting the hyperparameters of theUA.The experimental performance evaluation results showed that the classification performance of CNNs improved by up to 5%through the UA,although most of them showed similar performance to the traditional activation function.
基金funded by National Natural Science Foundation of China(Grant No.41972264)Zhejiang Provincial Natural Science Foundation of China(Grant No.LR22E080002)the Observation and Research Station of Geohazards in Zhejiang,Ministry of Natural Resources,China(Grant No.ZJDZGCZ-2021).
文摘The geometric characteristics of fractures within a rock mass can be inferred by the data sampling from boreholes or exposed surfaces.Recently,the universal elliptical disc(UED)model was developed to represent natural fractures,where the fracture is assumed to be an elliptical disc and the fracture orientation,rotation angle,length of the long axis and ratio of short-long axis lengths are considered as variables.This paper aims to estimate the fracture size-and azimuth-related parameters in the UED model based on the trace information from sampling windows.The stereological relationship between the trace length,size-and azimuth-related parameters of the UED model was established,and the formulae of the mean value and standard deviation of trace length were proposed.The proposed formulae were validated via the Monte Carlo simulations with less than 5%of error rate between the calculated and true values.With respect to the estimation of the size-and azimuth-related parameters using the trace length,an optimization method was developed based on the pre-assumed size and azimuth distribution forms.A hypothetical case study was designed to illustrate and verify the parameter estimation method,where three combinations of the sampling windows were used to estimate the parameters,and the results showed that the estimated values could agree well with the true values.Furthermore,a hypothetical three-dimensional(3D)elliptical fracture network was constructed,and the circular disc,non-UED and UED models were used to represent it.The simulated trace information from different models was compared,and the results clearly illustrated the superiority of the proposed UED model over the existing circular disc and non-UED models。
文摘Somalia is a country facing numerous challenges in achieving universal health coverage (UHC) and ensuring adequate healthcare financing, This article explores the complexities and obstacles that Somalia must overcome in its pursuit of UHC, the paper begins by providing an overview of the current healthcare landscape in Somalia, highlighting the lack of infrastructure, political instability, and limited financial resources that hinder the establishment of a comprehensive and equitable healthcare system. It then examines the role of international aid and non-governmental organizations (NGOs) in filling the healthcare gap, while emphasizing the need for a more sustainable, domestically financed solution. Drawing on a range of data sources and case studies, the article proposes a multi-faceted approach to strengthen healthcare governance, improve resource allocation, and foster local capacity building, the study delves into the unique obstacles that Somalia faces, including a lack of infrastructure, political instability, and limited financial resources, which hinder the establishment of a comprehensive and equitable healthcare system. The paper also examines the role of international aid and non-governmental organizations (NGOs) in filling the healthcare gap, while highlighting the need for a more sustainable, domestically financed solution. The findings underscore the importance of political commitment, international cooperation, and innovative financing mechanisms in advancing towards UHC in Somalia, providing valuable insights for other low resource, conflict affected settings.
文摘Recent research indicates that black holes can grow based on the expansion of the universe and not just through accretion and mergers. Two different models independently predicted that finding. One model, describing the relevant massive star remnants as “generic objects of dark energy”, rejects the traditional view of black holes while hypothesizing that dark energy causes the cosmologically coupled growth of these objects. The other model, based on the probabilistic spacetime theory, indicates the growth of black holes is based on the same spacetime mechanism underlying all universal expansion, and does so while leaving the traditional black hole conceptualization essentially intact. The fact these two models predicted this observational finding but did so from different perspectives suggests more can be learned by further study of their differences. This paper explores similarities and differences in the two models’ explanations for massive star remnants’ growth, concluding with suggestions for research testing their relative veracity. An exploration of the relative utility and parsimony of the two models is also described.
文摘Introduction: The launch of health insurance in the Republic of the Congo took place against a backdrop of extremely high costs for dialysis, which was not one of the services financed within this framework. The aim of this study is to assess the impact of including dialysis in the health insurance package in Congo. Methodology: This is a descriptive cross-sectional study with an evaluative aim, analyzing the impact of dialysis on the financing capacity of health insurance and health facilities to provide this type of care. Results: The results show that including dialysis in the universal health insurance package will require an additional financial effort of 6.20% of the current total financing capacity of the care basket. Most dialysis sessions are provided by the private health sector (87.5%), whose health facilities are unevenly distributed across the country, and concentrated in the country’s two major cities. This problem is the dual consequence of the very high cost of a dialysis session (average cost 140,234,375 FCFA or 229 US Dollars) and the number of patients under care, which will increase in the absence of effective and ongoing prevention efforts against chronic diseases in general and end-stage renal failure in particular. Conclusion: Dialysis is a high-impact public health intervention. The impact of its inclusion in the universal health insurance care package is difficult to bear financially. For dialysis to be covered by universal health insurance, additional funding and improved technical facilities are needed.
文摘In this work, we show that it is possible to establish coordinate transformations between inertial reference frames in the theory of special relativity with a minimum universal speed of physical transmissions. The established coordinate transformations, referred to as modified Lorentz transformations because they have almost identical form to the Lorentz transformations, also comply with the requirement of invariance of the Minkowski line element. Particularly, the minimum universal speed can be associated with the phase speed of de Broglie matter wave. As application, we also discuss the possibility to formulate relativistic classical and quantum mechanics for the special relativity associated with the modified Lorentz transformations, which describes physical processes that represent an expansion or a collapsing of massive quantum particles.
文摘In the example of formulating the Universal Declara-tion of Human Rights in 1948,which involved international human rights discourse,the“cross-cultural consensus”put forward based on Confucian culture by Zhang pengchun,the Chinese representative at that time,is widely considered an empirical reference for resolving confrontations and conflicts in the practice of human rights discourse.However,the effectiveness of this kind of cross-cultural consensus in addressing confrontations and conflicts is worth considering.Under the presumption of cultural differences,any attempt to resolve confrontations and conflicts in the human rights discourse must address the inherently controversial issues.the settlement of disputes and differences depends on how deep the consensus involves the values.Based on this,it reveals that the effectiveness of Zhang pengchun’s so-called contribution is limited.therefore,we should not overstate its relevance to the current human rights discourse.
文摘Results of analytical studies of the physical properties of the function and number of empirical macrohardness based on the standard experimental force diagram of kinetic macroindentation by a sphere.An analytical comparison method and a criterion for the similarity of the physical and empirical macrohardness of a material are proposed.The physical properties of the hardness measurement process using the Calvert-Johnson method are shown.The physical reasons for the size effect when measuring macrohardness are considered.The universal physical unit and standard of macrohardness of kinetic macroindentation by a sphere is substantiated.
文摘In the present paper, an efficient algorithm based on the continued fractions theory was established for the universal Y’s functions of space dynamics. The algorithm is valid for any conic motion (elliptic, parabolic or hyperbolic).
文摘What and how we translate are questions often argued about. No matter what kind of answers one may give, priority in translation should be granted to meaning, especially those meanings that exist in all concerned languages. This research defines them as universal sememes, and the study of them as universal semantics, of which applications are also briefly looked into.
文摘目的:探究观察3M Single Bond Universal粘接系统对前牙E-max铸瓷贴面修复的远期疗效。方法:选择2017年5月-2019年5月笔者医院收治的需前牙E-max铸瓷贴面修复患者63例(患牙113颗)为研究对象,均行经典贴面修复,根据粘接系统的不同将患者分为观察组(患者21例,患牙40颗,采用3M Single Bond Universal粘接系统)、对照1组(患者21例,患牙36颗,采用VariolinkⅡ粘接系统)、对照2组(患者21例,患牙37颗,采用BISCO CHOICE 2粘接系统)。治疗后三组均于1周、3个月、12个月时进行随访,观察三组治疗后1周、3个月、12个月内贴面修复效果、贴面修复失败率及不良反应发生率。结果:术后1周,三组患者均无失败案例;对照1组存在2颗修复体保存完整度为Ⅰ级的患牙,对照2组存在3颗修复体保存完整度为I级的患牙,观察组未存在该类患者;术后12个月,观察组存在1颗修复体保存完整度Ⅱ级患牙,对照1组存在1颗保存完整度I级患牙,3颗修复体保存完整度Ⅱ级患牙,对照2组存在2颗保存完整度I级患牙,3颗修复体保存完整度Ⅱ级患牙。三组患者治疗效果比较,差异无统计学意义(P>0.05);术后1周、3个月、12个月三组贴面修复失败率比较,差异无统计学意义(P>0.05);随访期间内,三组患者不良反应情况比较差异均无统计学意义(P>0.05)。结论:对于前牙E-max铸瓷贴面修复患者,选取合适的适应证,并做好备牙步骤,3M Single Bond Universal与经典VariolinkⅡ粘接系统及BISCO CHOICE 2粘接系统治疗效果并无显著差异,值得在临床推广使用。
