This study aims to evaluate the role of Jordanian veterinarians in terms of their knowledge,attitudes and common practices in combating antimicrobial resistance(AMR)and summarize the registered veterinary drugs betwee...This study aims to evaluate the role of Jordanian veterinarians in terms of their knowledge,attitudes and common practices in combating antimicrobial resistance(AMR)and summarize the registered veterinary drugs between 20172020.Descriptive study data were collected using a standardized questionnaire that focused on the knowledge,attitudes,and practices of Jordanian veterinarians.The findings were analyzed descriptively;84%of the participants agreed with the statement on the definition of AMR.The majority(95.65%)of participants agreed that AMR is a challenge for the veterinary sector in Jordan and that it should be prioritized over other zoonotic diseases.Approximately 69%of the participants believed that the misuse and overuse of antimicrobials by unqualified,fraudulent,or unauthorized practitioners is the primary reason for the rise of cases associated with AMR and the challenges that accompany these.The most common practice among the respondents in this study was to recommend clients(e.g.,farmers and owners)to practice good animal husbandry(80.00%).The study also revealed that there was a significant difference(p=O.015)between attendance at AMR training sessions and the professional sector(private,public,and academic)of the veterinarians.This study underscores the importance of implementing a continuous education program on AMR so as to enhance the all-round knowledge of veterinarians and improve their advisory skills.In addition,laws should be enacted to ensure that veterinarians prescribe the correct antimicrobials and to improve surveillance systems for monitoring the use of antimicrobials in veterinary medicine.展开更多
Education of veterinarians in animal welfare issues is important to improve the welfare and health of animals. A questionnaire to 250 veterinarians related to their knowledge on animal welfare issues has been carried ...Education of veterinarians in animal welfare issues is important to improve the welfare and health of animals. A questionnaire to 250 veterinarians related to their knowledge on animal welfare issues has been carried out at the Veterinary School of the University of the Republic, Uruguay, during March-April 2012. The questions were related to the courses on animal welfare veterinarians received, their main field of work, the importance given to the information offered and the quality of the topics addressed. From the total of veterinarians surveyed, 45% （112） answered the questionnaire. Of those who responded, 47% attended to three or more animal welfare courses, 18% assisted to two courses and 22% to one. The occupation of the 82% of respondents was with beef and dairy cattle （large animals） or in the meat industry equally. 10% works with small animals （especially pets） and poultry （production and industry）. The 95% of respondents considered that animal welfare is very important for their daily work with animals 65% reported that animal welfare concepts have high applicability in their job. 85% considered that animal welfare should be part of the veterinary curricula and 100% expressed their compliance to be present in other courses on the subject. These results emphasize the importance afforded by Uruguayan veterinarians to improve their knowledge on animal welfare and to continue including specific courses in the veterinary curricula.展开更多
A Chinese expert in Mozambique helps standardize and support the local development of veterinary medicine When Yue Chenghe’s phone rang unexpectedly,he picked it up and heard an anxious voice at the other end:"M...A Chinese expert in Mozambique helps standardize and support the local development of veterinary medicine When Yue Chenghe’s phone rang unexpectedly,he picked it up and heard an anxious voice at the other end:"Mr.Yue,the real-time image of the biological microscope has suddenly disappeared!"展开更多
Ceftazidime-avibactam (CZA) is a recently approved combination synthetic β-lactamase inhibitor used in human clinical medicine. Cases of CZA resistance in humans have already been reported, but limited research has i...Ceftazidime-avibactam (CZA) is a recently approved combination synthetic β-lactamase inhibitor used in human clinical medicine. Cases of CZA resistance in humans have already been reported, but limited research has investigated CZA resistance in pets. This study explored the prevalence and transmission of CZA-resistant Escherichia coli (CZAREC) among pets, their owners, veterinarians, and the environment in animal hospitals. A total of 5,419 clinical samples were collected from dogs and cats, along with samples from the environment (n = 5,843), veterinarians (n = 557), and pet owners (n = 368) in animal hospitals. From these samples, 760 Escherichia coli (E. coli) isolates were obtained, out of which 60 were identified as CZAREC. These included 34 isolates from the environment (9.14 %, n = 372), three from veterinarians (8.11 %, n = 37), and 23 from animals (6.82 %, n = 337). No CZAREC isolates were found in pet owners. The predominant sequence types of CZARECs were ST156 (n = 20), ST410 (n = 19) and ST101 (n = 7). Bayesian analysis revealed six clusters comprising 47 isolates from the hospital environment, pets, and veterinaries, displaying genetic relatedness of less than 100 core genome single nucleotide polymorphisms (cgSNPs) between any two isolates in each cluster. Some CZAREC isolates with high genetic similarity persisted in the same animal hospital for four to six months. Moreover, discriminant analysis of principal components indicated that most isolates from different hosts shared a genetic source in the human/dog/cat merged cluster. Overall, evidence of CZARECs transmission was found among pets, the environment, and veterinarians in animal hospitals. The findings emphasize the importance of monitoring CZARECs in the veterinary clinical setting to ensure the health of both pets and humans.展开更多
异恶唑啉类药物是一类新型的体外抗寄生虫药,它的作用机制是对无脊椎动物的谷氨酸(GLU)和γ-氨基丁酸(GABA)门控氯离子通道有较强的抑制活性。近年来,美国食品药品监督管理局(Food and Drug Administration, FDA)和欧洲药品管理局(Europ...异恶唑啉类药物是一类新型的体外抗寄生虫药,它的作用机制是对无脊椎动物的谷氨酸(GLU)和γ-氨基丁酸(GABA)门控氯离子通道有较强的抑制活性。近年来,美国食品药品监督管理局(Food and Drug Administration, FDA)和欧洲药品管理局(European Medicines Agency, EMA)批准了多个异恶唑啉的单一化合物或药物组合物。因此,无论对于兽医临床工作者还是兽药研发人员来说,更全面的了解异恶唑啉类药物的相关信息至关重要。本文综述了近年来批准上市的异恶唑啉药物,对其国内外研发情况、产品特点及主要产品的研发要点进行了分析阐述,对各种药物的药效学、药代动力学和安全性进行了归纳总结,以期为临床兽医选择药物及研发人员开发此类药物提供参考。展开更多
文摘This study aims to evaluate the role of Jordanian veterinarians in terms of their knowledge,attitudes and common practices in combating antimicrobial resistance(AMR)and summarize the registered veterinary drugs between 20172020.Descriptive study data were collected using a standardized questionnaire that focused on the knowledge,attitudes,and practices of Jordanian veterinarians.The findings were analyzed descriptively;84%of the participants agreed with the statement on the definition of AMR.The majority(95.65%)of participants agreed that AMR is a challenge for the veterinary sector in Jordan and that it should be prioritized over other zoonotic diseases.Approximately 69%of the participants believed that the misuse and overuse of antimicrobials by unqualified,fraudulent,or unauthorized practitioners is the primary reason for the rise of cases associated with AMR and the challenges that accompany these.The most common practice among the respondents in this study was to recommend clients(e.g.,farmers and owners)to practice good animal husbandry(80.00%).The study also revealed that there was a significant difference(p=O.015)between attendance at AMR training sessions and the professional sector(private,public,and academic)of the veterinarians.This study underscores the importance of implementing a continuous education program on AMR so as to enhance the all-round knowledge of veterinarians and improve their advisory skills.In addition,laws should be enacted to ensure that veterinarians prescribe the correct antimicrobials and to improve surveillance systems for monitoring the use of antimicrobials in veterinary medicine.
文摘Education of veterinarians in animal welfare issues is important to improve the welfare and health of animals. A questionnaire to 250 veterinarians related to their knowledge on animal welfare issues has been carried out at the Veterinary School of the University of the Republic, Uruguay, during March-April 2012. The questions were related to the courses on animal welfare veterinarians received, their main field of work, the importance given to the information offered and the quality of the topics addressed. From the total of veterinarians surveyed, 45% （112） answered the questionnaire. Of those who responded, 47% attended to three or more animal welfare courses, 18% assisted to two courses and 22% to one. The occupation of the 82% of respondents was with beef and dairy cattle （large animals） or in the meat industry equally. 10% works with small animals （especially pets） and poultry （production and industry）. The 95% of respondents considered that animal welfare is very important for their daily work with animals 65% reported that animal welfare concepts have high applicability in their job. 85% considered that animal welfare should be part of the veterinary curricula and 100% expressed their compliance to be present in other courses on the subject. These results emphasize the importance afforded by Uruguayan veterinarians to improve their knowledge on animal welfare and to continue including specific courses in the veterinary curricula.
文摘A Chinese expert in Mozambique helps standardize and support the local development of veterinary medicine When Yue Chenghe’s phone rang unexpectedly,he picked it up and heard an anxious voice at the other end:"Mr.Yue,the real-time image of the biological microscope has suddenly disappeared!"
基金the National Natural Science Foundation of China(32141002,81991535 and 32202863)China Postdoctoral Science Foundation(2021 M703528).
文摘Ceftazidime-avibactam (CZA) is a recently approved combination synthetic β-lactamase inhibitor used in human clinical medicine. Cases of CZA resistance in humans have already been reported, but limited research has investigated CZA resistance in pets. This study explored the prevalence and transmission of CZA-resistant Escherichia coli (CZAREC) among pets, their owners, veterinarians, and the environment in animal hospitals. A total of 5,419 clinical samples were collected from dogs and cats, along with samples from the environment (n = 5,843), veterinarians (n = 557), and pet owners (n = 368) in animal hospitals. From these samples, 760 Escherichia coli (E. coli) isolates were obtained, out of which 60 were identified as CZAREC. These included 34 isolates from the environment (9.14 %, n = 372), three from veterinarians (8.11 %, n = 37), and 23 from animals (6.82 %, n = 337). No CZAREC isolates were found in pet owners. The predominant sequence types of CZARECs were ST156 (n = 20), ST410 (n = 19) and ST101 (n = 7). Bayesian analysis revealed six clusters comprising 47 isolates from the hospital environment, pets, and veterinaries, displaying genetic relatedness of less than 100 core genome single nucleotide polymorphisms (cgSNPs) between any two isolates in each cluster. Some CZAREC isolates with high genetic similarity persisted in the same animal hospital for four to six months. Moreover, discriminant analysis of principal components indicated that most isolates from different hosts shared a genetic source in the human/dog/cat merged cluster. Overall, evidence of CZARECs transmission was found among pets, the environment, and veterinarians in animal hospitals. The findings emphasize the importance of monitoring CZARECs in the veterinary clinical setting to ensure the health of both pets and humans.
文摘异恶唑啉类药物是一类新型的体外抗寄生虫药,它的作用机制是对无脊椎动物的谷氨酸(GLU)和γ-氨基丁酸(GABA)门控氯离子通道有较强的抑制活性。近年来,美国食品药品监督管理局(Food and Drug Administration, FDA)和欧洲药品管理局(European Medicines Agency, EMA)批准了多个异恶唑啉的单一化合物或药物组合物。因此,无论对于兽医临床工作者还是兽药研发人员来说,更全面的了解异恶唑啉类药物的相关信息至关重要。本文综述了近年来批准上市的异恶唑啉药物,对其国内外研发情况、产品特点及主要产品的研发要点进行了分析阐述,对各种药物的药效学、药代动力学和安全性进行了归纳总结,以期为临床兽医选择药物及研发人员开发此类药物提供参考。
