研究目的:为探究国际孕期体力活动相关研究的热点及其演变进程,进而为我国孕期体力活动研究提供理论支撑。研究方法:以Web of Science、Pubmed等多个核心数据库收录的3769篇国际孕期体力活动相关文献为样本,依据文献计量学基本原理,基...研究目的:为探究国际孕期体力活动相关研究的热点及其演变进程,进而为我国孕期体力活动研究提供理论支撑。研究方法:以Web of Science、Pubmed等多个核心数据库收录的3769篇国际孕期体力活动相关文献为样本,依据文献计量学基本原理,基于关键词共现、引文分析、共引分析等计量方法,利用VOS viewer 1.68软件绘制出知识图谱,并通过可视化图谱展现国际孕期体力活动研究的外在特征、主题热点及演进历程。研究结论:30多年来国际孕期体力活动的研究力量主要集中在美、英等发达国家,且高校为主力军;研究学科主要分布在产科学、妇科学、病因学、流行病学和营养学,运动科学相对滞后;研究的热点主要体现在孕期体力活动对母体健康及并发症风险的影响,对胎儿发育及子代长远健康影响,与妊娠结局的关系,孕期体力活动的推荐标准,孕期体力活动的科学测量与评估等六大方面;研究热点除了始终围绕着“孕妇”、“胎儿”、“健康”、“安全”这一主线演进外,也呈现出随年度变化的阶段性特征;高频关键词如“孕期体力活动”、“孕期体育锻炼”、“慢性病”、“安全性”、“妊娠结局”、“母体胎儿健康”、“测量与评价”将继续成为未来一段时间内国际孕期体力活动研究的主要热点;而体现健康与幸福、以人为本发展战略的“建成环境”、“心理健康”、“表观遗传”、“子代长远健康”、“孕期体力活动推荐量”与“可穿戴装备”、“监测方法”、“调控机制”、“糖脂代谢”等也将成为下一时期的孕期体力活动研究热点。展开更多
通过系统梳理国际颠覆性创新理论的研究概况,加快探索适合我国创新实践情境的理论体系。运用VOS viewer软件,采用知识图谱和聚类分析研究方法,以1995—2021年Web of Science数据库核心合集收录的3218篇颠覆性创新研究主题的文献数据作...通过系统梳理国际颠覆性创新理论的研究概况,加快探索适合我国创新实践情境的理论体系。运用VOS viewer软件,采用知识图谱和聚类分析研究方法,以1995—2021年Web of Science数据库核心合集收录的3218篇颠覆性创新研究主题的文献数据作为研究对象,对国际颠覆性创新研究进行了期刊、作者、国家、机构、文献共被引分析和关键词共现分析,研究发现:从研究概况来看,颠覆性创新研究自2007年进入快速发展阶段,且美英两国的学者和研究机构引领了颠覆性创新研究。颠覆性创新的提出者CHRISTENSEN教授及其所在的研究机构-哈佛大学具有极高的威望;颠覆性创新理论作为战略管理理论,在Strategic Management Journal上发表的论文影响力位列第一;从研究热点来看,国际颠覆性创新研究主要形成了颠覆性创新绩效的影响因素、颠覆性创新在教育和医疗等公共服务行业中的应用、颠覆性创新促进社会可持续发展、颠覆性创新冲击社会-技术体系以及颠覆性创新发展的治理研究五大研究热点;从演进路径来看,颠覆性创新形成了从对单个行业的影响扩展到对创新生态系统的系统性颠覆再到对社会-技术体系的范式颠覆的演进路径。最后,文章提出了3个颠覆性创新的未来研究方向,包括颠覆性创新的应用范围将更广泛,治理主体更加多元以及与社会福利提升的关系将更紧密。展开更多
【目的】采用文献计量学分析方法,探讨针灸治疗焦虑症的现状趋势和研究热点,旨在为今后的研究提供基础和参考。【方法】通过中国知网期刊全文数据库(CNKI)和科技引文索引(Web of Science,WOS)数据库,搜索从数据库建库至2022年4月期间针...【目的】采用文献计量学分析方法,探讨针灸治疗焦虑症的现状趋势和研究热点,旨在为今后的研究提供基础和参考。【方法】通过中国知网期刊全文数据库(CNKI)和科技引文索引(Web of Science,WOS)数据库,搜索从数据库建库至2022年4月期间针灸治疗焦虑症的相关文献。利用Cite Space和VOS viewer对其发文量、所在国家(地区)和机构、共被引文献、共现关键词、突发关键词以及相关中心度进行分析。【结果】通过计算机检索,分别得到CNKI文献1167篇、WOS文献985篇,年发文量呈现波动上升的趋势。中国(351篇)和成都中医药大学(43篇)分别为最具生产力的国家(地区)和机构,国家合作以中国、美国为中心,但机构之间合作并不紧密。关键词及被引文献分析显示,研究以躯体疾病伴发焦虑为主,抑郁和疼痛是最常被研究的伴随症状。WOS中研究类型以系统评价和随机对照试验(RCT)为主,CNKI则以综述居多,均少见针灸治疗焦虑症相关机制的深入研究。对焦虑患者生活质量的关注可能成为未来针灸治疗焦虑症的研究重点。【结论】采用文献计量学方法对针刺治疗焦虑症的相关文献进行知识图谱分析,有助于研究者确定该领域的现状、热点和前沿趋势,并进一步探索针刺治疗焦虑症的未来研究方向。展开更多
BACKGROUND Glycosylation,a commonly occurring post-translational modification,is highly expressed in several tumors,specifically in those of the digestive system,and plays a role in various cellular pathophysiological...BACKGROUND Glycosylation,a commonly occurring post-translational modification,is highly expressed in several tumors,specifically in those of the digestive system,and plays a role in various cellular pathophysiological mechanisms.Although the importance and detection methods of glycosylation in digestive system tumors have garnered increasing attention in recent years,bibliometric analysis of this field remains scarce.The present study aims to identify the developmental trends and research hotspots of glycosylation in digestive system tumors.AIM To find and identify the developmental trends and research hotspots of glycosylation in digestive system tumors.METHODS We obtained relevant literature from the Web of Science Core Collection and employed VOSviewer 1.6.19 and CiteSpace(version 6.1.R6)to perform bibliometric analysis.RESULTS A total of 2042 documents spanning from 1978 to the present were analyzed,with the research process divided into three phases:the period of obscurity(1978-1990),continuous development period(1991-2006),and the rapid outbreak period(2007-2023).These documents were authored by researchers from 66 countries or regions,with the United States and China leading in terms of publication output.Reis Celso A had the highest number of publications,while Pinho SS was the most cited author.Co-occurrence analysis revealed the most popular keywords in this field are glycosylation,expression,cancer,colorectal cancer,and pancreatic cancer.Furthermore,the Journal of Proteome Research was the most prolific journal in terms of publications,while the Journal of Biological Chemistry had the most citations.CONCLUSION The bibliometric analysis shows current research focus is primarily on basic research in this field.However,future research should aim to utilize glycosylation as a target for treating tumor patients.展开更多
BACKGROUND Lack of mobilization and prolonged stay in the intensive care unit(ICU)are major factors resulting in the development of ICU-acquired muscle weakness(ICUAW).ICUAW is a type of skeletal muscle dysfunction an...BACKGROUND Lack of mobilization and prolonged stay in the intensive care unit(ICU)are major factors resulting in the development of ICU-acquired muscle weakness(ICUAW).ICUAW is a type of skeletal muscle dysfunction and a common complication of patients after cardiac surgery,and may be a risk factor for prolonged duration of mechanical ventilation,associated with a higher risk of readmission and higher mortality.Early mobilization in the ICU after cardiac surgery has been found to be low with a significant trend to increase over ICU stay and is also associated with a reduced duration of mechanical ventilation and ICU length of stay.Neuromuscular electrical stimulation(NMES)is an alternative modality of exercise in patients with muscle weakness.A major advantage of NMES is that it can be applied even in sedated patients in the ICU,a fact that might enhance early mobilization in these patients.AIM To evaluate safety,feasibility and effectiveness of NMES on functional capacity and muscle strength in patients before and after cardiac surgery.METHODS We performed a search on Pubmed,Physiotherapy Evidence Database(PEDro),Embase and CINAHL databases,selecting papers published between December 2012 and April 2023 and identified published randomized controlled trials(RCTs)that included implementation of NMES in patients before after cardiac surgery.RCTs were assessed for methodological rigor and risk of bias via the PEDro.The primary outcomes were safety and functional capacity and the secondary outcomes were muscle strength and function.RESULTS Ten studies were included in our systematic review,resulting in 703 participants.Almost half of them performed NMES and the other half were included in the control group,treated with usual care.Nine studies investigated patients after cardiac surgery and 1 study before cardiac surgery.Functional capacity was assessed in 8 studies via 6MWT or other indices,and improved only in 1 study before and in 1 after cardiac surgery.Nine studies explored the effects of NMES on muscle strength and function and,most of them,found increase of muscle strength and improvement in muscle function after NMES.NMES was safe in all studies without any significant complication.CONCLUSION NMES is safe,feasible and has beneficial effects on muscle strength and function in patients after cardiac surgery,but has no significant effect on functional capacity.展开更多
背景:探讨皮质骨轨迹螺钉的研究现状及发展趋势,了解皮质骨轨迹螺钉的研究方向及热点,有助于研究者把握该领域最新信息及发展趋势。目的:探究皮质骨轨迹螺钉的国际研究现状以及未来的发展趋势。方法:在Web of Science核心合集数据库中检...背景:探讨皮质骨轨迹螺钉的研究现状及发展趋势,了解皮质骨轨迹螺钉的研究方向及热点,有助于研究者把握该领域最新信息及发展趋势。目的:探究皮质骨轨迹螺钉的国际研究现状以及未来的发展趋势。方法:在Web of Science核心合集数据库中检索2000-01-01/2021-10-28期间发表的与皮质骨轨迹螺钉相关的英文文献,采用文献计量方法对收集到的文献进行统计和分析,采用VOS viewer软件对这些文献进行可视化研究,分析皮质骨轨迹螺钉的研究热点及发展趋势。结果与结论:①共纳入426篇文献,皮质骨轨迹螺钉的全球研究发表量逐年增加,2020年发表文章最多,共发表文章64篇;其中美国发文量最多,对全球贡献最大,居第1位(172篇),中国发文量为84篇,排在第2位;②《WORLD NEUROSURGERY》刊出的相关论文数量最多,为33篇;美国国立卫生研究院及美国卫生人类服务部是基金资助最多的2个机构;③MATSUKAWA K是发表文章最多的作者,为19篇,YATO Y排在第2位,发表文章为14篇;④从皮质骨轨迹螺钉研究的可视化分析来看,对该领域的研究还有很大的探索空间,文章发表数量将不断增加,美国和日本在这一领域处于领先地位,中国紧随其后,近年来的研究方向主要集中在皮质骨轨迹螺钉手术治疗方面。展开更多
51. Le thermalisme se développe a) Evian.b) Vichy.c) Perrier.52. En mai, de nombreux gitans se rendent en pèlerinagea) Aigues-Mortes.b) aux Saintes-Maries-de-la-Mer.c) au Salin-de-Giraud.53. Tous les F...51. Le thermalisme se développe a) Evian.b) Vichy.c) Perrier.52. En mai, de nombreux gitans se rendent en pèlerinagea) Aigues-Mortes.b) aux Saintes-Maries-de-la-Mer.c) au Salin-de-Giraud.53. Tous les Franais connaissent le Mont-Saint-Michel car c’esta) un lieu de pèlerinage.b) un monument très visité.c) le plus haut sommet des Pyrénées.展开更多
文摘研究目的:为探究国际孕期体力活动相关研究的热点及其演变进程,进而为我国孕期体力活动研究提供理论支撑。研究方法:以Web of Science、Pubmed等多个核心数据库收录的3769篇国际孕期体力活动相关文献为样本,依据文献计量学基本原理,基于关键词共现、引文分析、共引分析等计量方法,利用VOS viewer 1.68软件绘制出知识图谱,并通过可视化图谱展现国际孕期体力活动研究的外在特征、主题热点及演进历程。研究结论:30多年来国际孕期体力活动的研究力量主要集中在美、英等发达国家,且高校为主力军;研究学科主要分布在产科学、妇科学、病因学、流行病学和营养学,运动科学相对滞后;研究的热点主要体现在孕期体力活动对母体健康及并发症风险的影响,对胎儿发育及子代长远健康影响,与妊娠结局的关系,孕期体力活动的推荐标准,孕期体力活动的科学测量与评估等六大方面;研究热点除了始终围绕着“孕妇”、“胎儿”、“健康”、“安全”这一主线演进外,也呈现出随年度变化的阶段性特征;高频关键词如“孕期体力活动”、“孕期体育锻炼”、“慢性病”、“安全性”、“妊娠结局”、“母体胎儿健康”、“测量与评价”将继续成为未来一段时间内国际孕期体力活动研究的主要热点;而体现健康与幸福、以人为本发展战略的“建成环境”、“心理健康”、“表观遗传”、“子代长远健康”、“孕期体力活动推荐量”与“可穿戴装备”、“监测方法”、“调控机制”、“糖脂代谢”等也将成为下一时期的孕期体力活动研究热点。
文摘【目的】采用文献计量学分析方法,探讨针灸治疗焦虑症的现状趋势和研究热点,旨在为今后的研究提供基础和参考。【方法】通过中国知网期刊全文数据库(CNKI)和科技引文索引(Web of Science,WOS)数据库,搜索从数据库建库至2022年4月期间针灸治疗焦虑症的相关文献。利用Cite Space和VOS viewer对其发文量、所在国家(地区)和机构、共被引文献、共现关键词、突发关键词以及相关中心度进行分析。【结果】通过计算机检索,分别得到CNKI文献1167篇、WOS文献985篇,年发文量呈现波动上升的趋势。中国(351篇)和成都中医药大学(43篇)分别为最具生产力的国家(地区)和机构,国家合作以中国、美国为中心,但机构之间合作并不紧密。关键词及被引文献分析显示,研究以躯体疾病伴发焦虑为主,抑郁和疼痛是最常被研究的伴随症状。WOS中研究类型以系统评价和随机对照试验(RCT)为主,CNKI则以综述居多,均少见针灸治疗焦虑症相关机制的深入研究。对焦虑患者生活质量的关注可能成为未来针灸治疗焦虑症的研究重点。【结论】采用文献计量学方法对针刺治疗焦虑症的相关文献进行知识图谱分析,有助于研究者确定该领域的现状、热点和前沿趋势,并进一步探索针刺治疗焦虑症的未来研究方向。
基金the National Natural Science Foundation of China,No.82072662Shanghai Municipal Education Commission-Gaofeng Clinical Medicine Grant Support,No.2019142+1 种基金Shanghai Three-year Action Plan to Promote Clinical Skills and Clinical Innovation in Municipal Hospitals,No.SHDC2020CR4022the 2021 Shanghai“Rising Stars of Medical Talent”Youth Development Program:Outstanding Youth Medical Talents.
文摘BACKGROUND Glycosylation,a commonly occurring post-translational modification,is highly expressed in several tumors,specifically in those of the digestive system,and plays a role in various cellular pathophysiological mechanisms.Although the importance and detection methods of glycosylation in digestive system tumors have garnered increasing attention in recent years,bibliometric analysis of this field remains scarce.The present study aims to identify the developmental trends and research hotspots of glycosylation in digestive system tumors.AIM To find and identify the developmental trends and research hotspots of glycosylation in digestive system tumors.METHODS We obtained relevant literature from the Web of Science Core Collection and employed VOSviewer 1.6.19 and CiteSpace(version 6.1.R6)to perform bibliometric analysis.RESULTS A total of 2042 documents spanning from 1978 to the present were analyzed,with the research process divided into three phases:the period of obscurity(1978-1990),continuous development period(1991-2006),and the rapid outbreak period(2007-2023).These documents were authored by researchers from 66 countries or regions,with the United States and China leading in terms of publication output.Reis Celso A had the highest number of publications,while Pinho SS was the most cited author.Co-occurrence analysis revealed the most popular keywords in this field are glycosylation,expression,cancer,colorectal cancer,and pancreatic cancer.Furthermore,the Journal of Proteome Research was the most prolific journal in terms of publications,while the Journal of Biological Chemistry had the most citations.CONCLUSION The bibliometric analysis shows current research focus is primarily on basic research in this field.However,future research should aim to utilize glycosylation as a target for treating tumor patients.
文摘BACKGROUND Lack of mobilization and prolonged stay in the intensive care unit(ICU)are major factors resulting in the development of ICU-acquired muscle weakness(ICUAW).ICUAW is a type of skeletal muscle dysfunction and a common complication of patients after cardiac surgery,and may be a risk factor for prolonged duration of mechanical ventilation,associated with a higher risk of readmission and higher mortality.Early mobilization in the ICU after cardiac surgery has been found to be low with a significant trend to increase over ICU stay and is also associated with a reduced duration of mechanical ventilation and ICU length of stay.Neuromuscular electrical stimulation(NMES)is an alternative modality of exercise in patients with muscle weakness.A major advantage of NMES is that it can be applied even in sedated patients in the ICU,a fact that might enhance early mobilization in these patients.AIM To evaluate safety,feasibility and effectiveness of NMES on functional capacity and muscle strength in patients before and after cardiac surgery.METHODS We performed a search on Pubmed,Physiotherapy Evidence Database(PEDro),Embase and CINAHL databases,selecting papers published between December 2012 and April 2023 and identified published randomized controlled trials(RCTs)that included implementation of NMES in patients before after cardiac surgery.RCTs were assessed for methodological rigor and risk of bias via the PEDro.The primary outcomes were safety and functional capacity and the secondary outcomes were muscle strength and function.RESULTS Ten studies were included in our systematic review,resulting in 703 participants.Almost half of them performed NMES and the other half were included in the control group,treated with usual care.Nine studies investigated patients after cardiac surgery and 1 study before cardiac surgery.Functional capacity was assessed in 8 studies via 6MWT or other indices,and improved only in 1 study before and in 1 after cardiac surgery.Nine studies explored the effects of NMES on muscle strength and function and,most of them,found increase of muscle strength and improvement in muscle function after NMES.NMES was safe in all studies without any significant complication.CONCLUSION NMES is safe,feasible and has beneficial effects on muscle strength and function in patients after cardiac surgery,but has no significant effect on functional capacity.
文摘51. Le thermalisme se développe a) Evian.b) Vichy.c) Perrier.52. En mai, de nombreux gitans se rendent en pèlerinagea) Aigues-Mortes.b) aux Saintes-Maries-de-la-Mer.c) au Salin-de-Giraud.53. Tous les Franais connaissent le Mont-Saint-Michel car c’esta) un lieu de pèlerinage.b) un monument très visité.c) le plus haut sommet des Pyrénées.
