In this paper, a reaction-diffusion equation with discrete time delay that describes the dynamics of the blood cell production is analyzed. The existence of the traveling wave front solutions is demonstrated using the...In this paper, a reaction-diffusion equation with discrete time delay that describes the dynamics of the blood cell production is analyzed. The existence of the traveling wave front solutions is demonstrated using the technique of upper and lower solutions and the associated monotone iteration.展开更多
We investigate the light propagation by means of simulations of wavefronts and light cones for Kerr spacetimes. Simulations of this kind give us a new insight to better understand the light propagation in presence of ...We investigate the light propagation by means of simulations of wavefronts and light cones for Kerr spacetimes. Simulations of this kind give us a new insight to better understand the light propagation in presence of massive rotating black holes. A relevant result is that wavefronts are backscattered with winding around the black hole. To generate these visualizations, an interactive computer program with a graphical user interface, called JWFront, was written in Java.展开更多
This paper is devoted to the study of traveling wavefronts for a three-component Lotka-Volterra system with nonlocal dispersal.This system arises in the study of three-species competition model in which there is no co...This paper is devoted to the study of traveling wavefronts for a three-component Lotka-Volterra system with nonlocal dispersal.This system arises in the study of three-species competition model in which there is no competition between two of these three species.It has been shown that this system admits a bistable traveling wavefront.In this paper,we further investigate the stability of bistable traveling wavefronts.By constructing suitable super-and sub-solutions and using a dynamical system approach,we obtain the globally asymptotic stability of the bistable traveling wavefronts.展开更多
Optical endoscopy has become an essential diagnostic and therapeutic approach in modern biomedicine for directly observing organs and tissues deep inside the human body,enabling non-invasive,rapid diagnosis and treatm...Optical endoscopy has become an essential diagnostic and therapeutic approach in modern biomedicine for directly observing organs and tissues deep inside the human body,enabling non-invasive,rapid diagnosis and treatment.Optical fiber endoscopy is highly competitive among various endoscopic imaging techniques due to its high flexibility,compact structure,excellent resolution,and resistance to electromagnetic interference.Over the past decade,endoscopes based on a single multimode optical fiber(MMF)have attracted widespread research interest due to their potential to significantly reduce the footprint of optical fiber endoscopes and enhance imaging capabilities.In comparison with other imaging principles of MMF endoscopes,the scanning imaging method based on the wavefront shaping technique is highly developed and provides benefits including excellent imaging contrast,broad applicability to complex imaging scenarios,and good compatibility with various well-established scanning imaging modalities.In this review,various technical routes to achieve light focusing through MMF and procedures to conduct the scanning imaging of MMF endoscopes are introduced.The advancements in imaging performance enhancements,integrations of various imaging modalities with MMF scanning endoscopes,and applications are summarized.Challenges specific to this endoscopic imaging technology are analyzed,and potential remedies and avenues for future developments are discussed.展开更多
This paper is concerned with the travelling wavefronts of a nonlocal dispersal cooperation model with harvesting and state-dependent delay,which is assumed to be an increasing function of the population density with l...This paper is concerned with the travelling wavefronts of a nonlocal dispersal cooperation model with harvesting and state-dependent delay,which is assumed to be an increasing function of the population density with lower and upper bound.Especially,state-dependent delay is introduced into a nonlocal reaction-diffusion model.The conditions of Schauder's fixed point theorem are proved by constructing a reasonable set of functionsΓ(see Section 2)and a pair of upper-lower solutions,so the existence of traveling wavefronts is established.The present study is continuation of a previous work that highlights the Laplacian diffusion.展开更多
A method for simulating acoustic wavefronts propagating under random sound speed conditions is presented.The approach applies a level set method to solve the Eikonal equation of high frequency acoustics for surfaces o...A method for simulating acoustic wavefronts propagating under random sound speed conditions is presented.The approach applies a level set method to solve the Eikonal equation of high frequency acoustics for surfaces of constant phase,instead of tracing rays.The Lagrangian nature often makes full-field ray solutions difficult to reconstruct.The level set method captures multiple-valued solutions on a fixed grid.It is straightforward to represent other sources of uncertainty in the input data using this model,which has an advantage over Monte Carlo approaches in that it yields an expression for the solution as a function of random variables.展开更多
Nano-3D printing has obtained widespread attention owing to its capacity to manufacture end-use components with nano-scale features in recent years.Multiphoton lithography(MPL)is one of the most promising 3D nanomanuf...Nano-3D printing has obtained widespread attention owing to its capacity to manufacture end-use components with nano-scale features in recent years.Multiphoton lithography(MPL)is one of the most promising 3D nanomanufacturing technologies,which has been widely used in manufacturing micro-optics,photonic crystals,microfluidics,meta-surface,and mechanical metamaterials.Despite of tremendous potential of MPL in laboratorial and industrial applications,simultaneous achievement of high throughput,high accuracy,high design freedom,and a broad range of material structuring capabilities remains a long-pending challenge.To address the issue,we propose an acousto-optic scanning with spatial-switching multispots(AOSS)method.Inertia-free acousto-optic scanning and nonlinear swept techniques have been developed for achieving ultrahigh-speed and aberration-free scanning.Moreover,a spatial optical switch concept has been implemented to significantly boost the lithography throughput while maintaining high resolution and high design freedom.An eight-foci AOSS system has demonstrated a record-high 3D printing rate of 7.6×10^(7)voxel s^(-1),which is nearly one order of magnitude higher than earlier scanning MPL,exhibiting its promise for future scalable 3D nanomanufacturing.展开更多
The stability of traveling wavefronts for a spatially nonlocal population model with quasi-monotonicity and delay is discussed in this article.It is shown that all monostable wavefronts are exponentially stable for la...The stability of traveling wavefronts for a spatially nonlocal population model with quasi-monotonicity and delay is discussed in this article.It is shown that all monostable wavefronts are exponentially stable for large speed with the help of weightedenergy method and comparison principle.The proper selection of the weighted function is necessary to overcome the difficulty caused by the nonlocal nonlinearity for establishing the energy estimates of solutions.展开更多
AIM:To compare if there is an improvement in visual functions with age-related cataracts between patients receiving a aspherical intraocular lens(IOL) based on corneal wavefront aberration and patients randomly assign...AIM:To compare if there is an improvement in visual functions with age-related cataracts between patients receiving a aspherical intraocular lens(IOL) based on corneal wavefront aberration and patients randomly assigned lenses.METHODS:A total of 124 eyes of 124 patients with age-related cataracts were placed in experimental group and a group receiving randomly assigned(RA) lenses.The experimental group was undergone Pentacam corneal spherical aberration measurement before surgery; the targeted range for residual total spherical aberration after surgery was set to 0-0.3 μm. Patients with a corneal spherical aberration <0.3 μm were implanted with a zero-spherical aberration advanced optics(AO) aspherical IOL and patients with an aberration ≥0.3 μm received a Tecnis Z9003 aspherical lens in experimental group. RA patients were randomly implanted with an AO lens or a Tecnis Z9003 lens. Three months after surgery total spherical aberration, photopic/mesopic contrast sensitivities, photopic/mesopic with glare contrast sensitivities, and logMAR vision were measured.RESULTS:Statistical analysis on logMAR vision showed no significant difference between two groups(P =0.413). The post-surgical total spherical aberration was 0.126 ±0.097 μm and 0.152 ±0.151 μm in the experimental and RA groups, respectively(P =0.12). The mesopic contrast sensitivities at spatial frequencies of 6,12 and 18 c/d in the experimental group were significantly higher than of the RA group(P =0.00; P =0.04;P =0.02). The mesopic with glare contrast sensitivity in the experimental group at a spatial frequency of 18 c/d was also significantly higher vs the RA group(P =0.01).CONCLUSION:Pre-surgical corneal spherical aberration measurement in cataract patients followed bycustomized selection of aspherical IOL implants improved mesopic contrast sensitivities at high spatial frequencies, and thus is a superior strategy compared to the random selection of aspherical intraocular lens implants.展开更多
Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike p...Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike polynomial coefficients. In addition, the promising prospect of virtual eye model is emphasized.展开更多
We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and geneti...We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and genetic algorithm(GA) is numerically simulated. Then, using a high speed digital micromirror device, we carry out light focusing experiments with the modified PSO algorithm and GA. The experimental results show that the modified PSO algorithm has greater robustness and faster convergence speed than GA. This modified PSO algorithm has great application prospects in optical focusing and imaging inside in vivo biological tissue, which possesses a complicated background.展开更多
AIM: To study the distribution of ocular higher-order aberrations(HOAs) and mesopic pupil size in individuals screened for refractive surgery. · METHODS: Ocular HOAs and mesopic pupil size were studied in 2 458 e...AIM: To study the distribution of ocular higher-order aberrations(HOAs) and mesopic pupil size in individuals screened for refractive surgery. · METHODS: Ocular HOAs and mesopic pupil size were studied in 2 458 eyes of 1 240 patients with myopia, myopic astigmatism and compound myopic astigmatism and 215 eyes of 110 patients with hyperopia, hyperopic astigmatism and compound hyperopic astigmatism using the Zywave aberrometer (Busch& Lomb). All patients had correctable refractive errors without a history of refractive surgery or underlying diseases. Root-mean-square values of HOAs, total spherical aberration, total coma and mesopic pupil size were analyzed. Ocular HOAs were measured across a ≥ 6.0 mm pupil, and pupil size measurements were performed under the mesopic condition. · RESULTS: The mean values of HOAs, total spherical aberration and total coma in the myopic group were 0.369 μm, ±0.233, 0.133±0.112μm and 0.330±0.188μm, respectively. In the hyperopic group the mean values of HOAs, total spherical aberration and total coma were 0.418μm±0.214, 0.202±0.209μm and 0.343±0.201μm, respectively. Hyperopes showed greater total HOAs (P <0.01) and total spherical aberration (P <0.01) compared to myopes. In age-matched analysis, only the amount of total spherical aberration was higher in the hyperopic group (P =0.05). Mesopic pupil size in the myopic group was larger (P ≤0.05). · CONCLUSION: The results suggested that significant levels of HOAs were found in both groups which are important for planning refractive surgeries on Iranians. There were significantly higher levels of total spherical aberration in hyperopes compared to myopes. Mesopic pupil size was larger in myopic group.展开更多
AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eye...AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.展开更多
Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltage...Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltages directly from wavefront slopes through pre-measuring the relational matrix between deformable mirror actuators and Hartmann wavefront sensor with perfect real-time characteristic and stability. However, with increasing the number of sub-apertures in wavefront sensor and deformable mirror actuators of adaptive optics systems, the matrix operation in direct gradient algorithm takes too much time, which becomes a major factor influencing control effect of adaptive optics systems. In this paper we apply an iterative wavefront control algorithm to high-resolution adaptive optics systems, in which the voltages of each actuator are obtained through iteration arithmetic, which gains great advantage in calculation and storage. For AO system with thousands of actuators, the computational complexity estimate is about O(n2) ～ O(n3) in direct gradient wavefront control algorithm, while the computational complexity estimate in iterative wavefront control algorithm is about O(n) ～(O(n)3/2), in which n is the number of actuators of AO system. And the more the numbers of sub-apertures and deformable mirror actuators, the more significant advantage the iterative wavefront control algorithm exhibits.展开更多
We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has l...We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has little relation with the change of the pump beam energies. Transverse parasitic lasing that might occur in CPA hardly affects the wavefront of the signal beam. Thermal effects were also considered in this study, and the results show that the thermal effect cumulated in multiple amplification processes also has no obvious influence on the wavefront of the signal beam for a single-shot frequency. The results presented in this paper confirmed experimentally that the amplification in a Ti:sapphire CPA system has little impact on the WFA of the signal beam and it is very helpful for wavefront correction of single-shot PW and multi-PW laser systems based on Ti:sapphire.展开更多
Current freeform illumination optical designs are mostly focused on producing prescribed irradiance distributions on planar targets.Here,we aim to design freeform optics that could generate a desired illumination on a...Current freeform illumination optical designs are mostly focused on producing prescribed irradiance distributions on planar targets.Here,we aim to design freeform optics that could generate a desired illumination on a curved target from a point source,which is still a challenge.We reduce the difficulties that arise from the curved target by involving its varying z-coordinates in the iterative wavefront tailoring(IWT)procedure.The new IWT-based method is developed under the stereographic coordinate system with a special mesh transformation of the source domain,which is suitable for light sources with light emissions in semi space such as LED sources.The first example demonstrates that a rectangular flat-top illumination can be generated on an undulating surface by a spherical-freeform lens for a Lambertian source.The second example shows that our method is also applicable for producing a non-uniform irradiance distribution in a circular region of the undulating surface.展开更多
文摘In this paper, a reaction-diffusion equation with discrete time delay that describes the dynamics of the blood cell production is analyzed. The existence of the traveling wave front solutions is demonstrated using the technique of upper and lower solutions and the associated monotone iteration.
文摘We investigate the light propagation by means of simulations of wavefronts and light cones for Kerr spacetimes. Simulations of this kind give us a new insight to better understand the light propagation in presence of massive rotating black holes. A relevant result is that wavefronts are backscattered with winding around the black hole. To generate these visualizations, an interactive computer program with a graphical user interface, called JWFront, was written in Java.
基金supported by NSF of China (11861056)NSF of Gansu Province (21JR7RA121)Department of Education of Gansu Province:Youth Doctoral Fund Project (2021QB-018).
文摘This paper is devoted to the study of traveling wavefronts for a three-component Lotka-Volterra system with nonlocal dispersal.This system arises in the study of three-species competition model in which there is no competition between two of these three species.It has been shown that this system admits a bistable traveling wavefront.In this paper,we further investigate the stability of bistable traveling wavefronts.By constructing suitable super-and sub-solutions and using a dynamical system approach,we obtain the globally asymptotic stability of the bistable traveling wavefronts.
基金supported by National Natural Science Foundation of China(62135007 and 61925502).
文摘Optical endoscopy has become an essential diagnostic and therapeutic approach in modern biomedicine for directly observing organs and tissues deep inside the human body,enabling non-invasive,rapid diagnosis and treatment.Optical fiber endoscopy is highly competitive among various endoscopic imaging techniques due to its high flexibility,compact structure,excellent resolution,and resistance to electromagnetic interference.Over the past decade,endoscopes based on a single multimode optical fiber(MMF)have attracted widespread research interest due to their potential to significantly reduce the footprint of optical fiber endoscopes and enhance imaging capabilities.In comparison with other imaging principles of MMF endoscopes,the scanning imaging method based on the wavefront shaping technique is highly developed and provides benefits including excellent imaging contrast,broad applicability to complex imaging scenarios,and good compatibility with various well-established scanning imaging modalities.In this review,various technical routes to achieve light focusing through MMF and procedures to conduct the scanning imaging of MMF endoscopes are introduced.The advancements in imaging performance enhancements,integrations of various imaging modalities with MMF scanning endoscopes,and applications are summarized.Challenges specific to this endoscopic imaging technology are analyzed,and potential remedies and avenues for future developments are discussed.
基金Supported by NSFC(Grant Nos.11771044,11871007)Foundation of Anhui University of Finance and Economics(Grant No.ACKYC19051)Major Research Projects of Natural Science in Colleges and Universities of Anhui Province(Grant No.KJ2017ZD35)
文摘This paper is concerned with the travelling wavefronts of a nonlocal dispersal cooperation model with harvesting and state-dependent delay,which is assumed to be an increasing function of the population density with lower and upper bound.Especially,state-dependent delay is introduced into a nonlocal reaction-diffusion model.The conditions of Schauder's fixed point theorem are proved by constructing a reasonable set of functionsΓ(see Section 2)and a pair of upper-lower solutions,so the existence of traveling wavefronts is established.The present study is continuation of a previous work that highlights the Laplacian diffusion.
文摘A method for simulating acoustic wavefronts propagating under random sound speed conditions is presented.The approach applies a level set method to solve the Eikonal equation of high frequency acoustics for surfaces of constant phase,instead of tracing rays.The Lagrangian nature often makes full-field ray solutions difficult to reconstruct.The level set method captures multiple-valued solutions on a fixed grid.It is straightforward to represent other sources of uncertainty in the input data using this model,which has an advantage over Monte Carlo approaches in that it yields an expression for the solution as a function of random variables.
基金National Key Research and Development Program of China(2021YFF0502700)National Natural Science Foundation of China(52275429,62205117)+4 种基金Innovation project of Optics Valley Laboratory(OVL2021ZD002)Hubei Provincial Natural Science Foundation of China(2022CFB792)Young Elite Scientists Sponsorship Program by CAST(2022QNRC001)West Light Foundation of the Chinese Academy of Sciences(xbzg-zdsys-202206)Knowledge Innovation Program of Wuhan-Shuguang。
文摘Nano-3D printing has obtained widespread attention owing to its capacity to manufacture end-use components with nano-scale features in recent years.Multiphoton lithography(MPL)is one of the most promising 3D nanomanufacturing technologies,which has been widely used in manufacturing micro-optics,photonic crystals,microfluidics,meta-surface,and mechanical metamaterials.Despite of tremendous potential of MPL in laboratorial and industrial applications,simultaneous achievement of high throughput,high accuracy,high design freedom,and a broad range of material structuring capabilities remains a long-pending challenge.To address the issue,we propose an acousto-optic scanning with spatial-switching multispots(AOSS)method.Inertia-free acousto-optic scanning and nonlinear swept techniques have been developed for achieving ultrahigh-speed and aberration-free scanning.Moreover,a spatial optical switch concept has been implemented to significantly boost the lithography throughput while maintaining high resolution and high design freedom.An eight-foci AOSS system has demonstrated a record-high 3D printing rate of 7.6×10^(7)voxel s^(-1),which is nearly one order of magnitude higher than earlier scanning MPL,exhibiting its promise for future scalable 3D nanomanufacturing.
基金Supported by the NSF of China(Grant No.11761046)Science and Technology Plan Foundation of Gansu Province of China(Grant No.20JR5RA411)Foundation of A Hundred Youth Talents Training Program of Lanzhou Jiaotong University.
文摘The stability of traveling wavefronts for a spatially nonlocal population model with quasi-monotonicity and delay is discussed in this article.It is shown that all monostable wavefronts are exponentially stable for large speed with the help of weightedenergy method and comparison principle.The proper selection of the weighted function is necessary to overcome the difficulty caused by the nonlocal nonlinearity for establishing the energy estimates of solutions.
文摘AIM:To compare if there is an improvement in visual functions with age-related cataracts between patients receiving a aspherical intraocular lens(IOL) based on corneal wavefront aberration and patients randomly assigned lenses.METHODS:A total of 124 eyes of 124 patients with age-related cataracts were placed in experimental group and a group receiving randomly assigned(RA) lenses.The experimental group was undergone Pentacam corneal spherical aberration measurement before surgery; the targeted range for residual total spherical aberration after surgery was set to 0-0.3 μm. Patients with a corneal spherical aberration <0.3 μm were implanted with a zero-spherical aberration advanced optics(AO) aspherical IOL and patients with an aberration ≥0.3 μm received a Tecnis Z9003 aspherical lens in experimental group. RA patients were randomly implanted with an AO lens or a Tecnis Z9003 lens. Three months after surgery total spherical aberration, photopic/mesopic contrast sensitivities, photopic/mesopic with glare contrast sensitivities, and logMAR vision were measured.RESULTS:Statistical analysis on logMAR vision showed no significant difference between two groups(P =0.413). The post-surgical total spherical aberration was 0.126 ±0.097 μm and 0.152 ±0.151 μm in the experimental and RA groups, respectively(P =0.12). The mesopic contrast sensitivities at spatial frequencies of 6,12 and 18 c/d in the experimental group were significantly higher than of the RA group(P =0.00; P =0.04;P =0.02). The mesopic with glare contrast sensitivity in the experimental group at a spatial frequency of 18 c/d was also significantly higher vs the RA group(P =0.01).CONCLUSION:Pre-surgical corneal spherical aberration measurement in cataract patients followed bycustomized selection of aspherical IOL implants improved mesopic contrast sensitivities at high spatial frequencies, and thus is a superior strategy compared to the random selection of aspherical intraocular lens implants.
基金National Natural Science Foundation of China (No. 61173182, No. 61179071)Applied Basic Research Project (No. 2011JY0124)International Cooperation and Exchange Project of Sichuan Province (No.2012HH0004)
文摘Wavefront aberration affects the quality of retinal image directly. This paper reviews the representation and reconstruction of wavefront aberration, as well as the construction of virtual eye model based on Zernike polynomial coefficients. In addition, the promising prospect of virtual eye model is emphasized.
基金Supported by the National Key Research and Development Program of China under Grant No 2017YFB1104500the Natural Science Foundation of Beijing under Grant No 7182091,the National Natural Science Foundation of China under Grant No 21627813the Fundamental Research Funds for the Central Universities under Grant No PYBZ1801
文摘We demonstrate a modified particle swarm optimization(PSO) algorithm to effectively shape the incident light with strong robustness and short optimization time. The performance of the modified PSO algorithm and genetic algorithm(GA) is numerically simulated. Then, using a high speed digital micromirror device, we carry out light focusing experiments with the modified PSO algorithm and GA. The experimental results show that the modified PSO algorithm has greater robustness and faster convergence speed than GA. This modified PSO algorithm has great application prospects in optical focusing and imaging inside in vivo biological tissue, which possesses a complicated background.
文摘AIM: To study the distribution of ocular higher-order aberrations(HOAs) and mesopic pupil size in individuals screened for refractive surgery. · METHODS: Ocular HOAs and mesopic pupil size were studied in 2 458 eyes of 1 240 patients with myopia, myopic astigmatism and compound myopic astigmatism and 215 eyes of 110 patients with hyperopia, hyperopic astigmatism and compound hyperopic astigmatism using the Zywave aberrometer (Busch& Lomb). All patients had correctable refractive errors without a history of refractive surgery or underlying diseases. Root-mean-square values of HOAs, total spherical aberration, total coma and mesopic pupil size were analyzed. Ocular HOAs were measured across a ≥ 6.0 mm pupil, and pupil size measurements were performed under the mesopic condition. · RESULTS: The mean values of HOAs, total spherical aberration and total coma in the myopic group were 0.369 μm, ±0.233, 0.133±0.112μm and 0.330±0.188μm, respectively. In the hyperopic group the mean values of HOAs, total spherical aberration and total coma were 0.418μm±0.214, 0.202±0.209μm and 0.343±0.201μm, respectively. Hyperopes showed greater total HOAs (P <0.01) and total spherical aberration (P <0.01) compared to myopes. In age-matched analysis, only the amount of total spherical aberration was higher in the hyperopic group (P =0.05). Mesopic pupil size in the myopic group was larger (P ≤0.05). · CONCLUSION: The results suggested that significant levels of HOAs were found in both groups which are important for planning refractive surgeries on Iranians. There were significantly higher levels of total spherical aberration in hyperopes compared to myopes. Mesopic pupil size was larger in myopic group.
文摘AIM: To compare the wavefront aberrations and corneal surface regularity between dry eye(DE) patients and normal subjects and assess its diagnostic performance for DE measured with OPD Scan-Ⅲ.METHODS: Fifty right eyes of 50 DE patients and 31 right eyes of normal subjects were included.The examinations for ocular surface including logarithm of the minimum angle of resolution best-corrected distance visual acuity(logMAR BCVA) the ocular surface disease index(OSDI), tear film break-up time(TBUT) and corneal fluorescein staining(CFS).OPD Scan-Ⅲ was used to measure anterior corneal aberrations including total corneal aberrations, high order aberration(HOA), coma, trefoil, spherical aberration(SA), standard deviation of corneal power(SDP), surface regularity index(SRI) and surface asymmetry index(SAI).Statistical analysis were assessed with nonparametric tests and Spearman’s correlations.All parameters were also analyzed for sensitivity, specificity, and receiver operating characteristics(ROC) curves.RESULTS: Wavefront aberrations parameters including total corneal aberrations, HOA, coma, trefoil, and SA in DE group were significantly higher than those in normal group(P<0.001).Corneal surface regularity parameters including SRI and SAI in DE group were significantly higher than both in normal group(P<0.05).All the wavefront aberrations parameters had significant correlations with ocular surface parameters(P<0.05).The logMAR BCVA had positive correlations with SAI and SRI(all P<0.001).CFS scores had positive correlations with SAI and SRI(all P<0.001).All the wavefront aberrations parameters showed good diagnosis sensitivity and specificity, however, the corneal regularity parameters showed only good specificity but poor sensitivity.The cut-off value selected for trefoil in diagnosis DE showed the highest area under the curve(AUC, 0.921) values as compared to the other parameters with sensitivity of 0.955 and specificity of 0.867.CONCLUSION: Wavefront aberrations and corneal surface regularity are increased in DE patients and also correlated with ocular surface parameters.Wavefront aberrations parameters have potential to be indicators to diagnosis and monitor DE.
基金supported by the National Key Scientific and Research Equipment Development Project of China(Grant No.ZDYZ2013-2)the National Natural Science Foundation of China(Grant No.11173008)the Sichuan Provincial Outstanding Youth Academic Technology Leaders Program,China(Grant No.2012JQ0012)
文摘Among all kinds of wavefront control algorithms in adaptive optics systems, the direct gradient wavefront control algorithm is the most widespread and common method. This control algorithm obtains the actuator voltages directly from wavefront slopes through pre-measuring the relational matrix between deformable mirror actuators and Hartmann wavefront sensor with perfect real-time characteristic and stability. However, with increasing the number of sub-apertures in wavefront sensor and deformable mirror actuators of adaptive optics systems, the matrix operation in direct gradient algorithm takes too much time, which becomes a major factor influencing control effect of adaptive optics systems. In this paper we apply an iterative wavefront control algorithm to high-resolution adaptive optics systems, in which the voltages of each actuator are obtained through iteration arithmetic, which gains great advantage in calculation and storage. For AO system with thousands of actuators, the computational complexity estimate is about O(n2) ～ O(n3) in direct gradient wavefront control algorithm, while the computational complexity estimate in iterative wavefront control algorithm is about O(n) ～(O(n)3/2), in which n is the number of actuators of AO system. And the more the numbers of sub-apertures and deformable mirror actuators, the more significant advantage the iterative wavefront control algorithm exhibits.
基金Project supported by the National Natural Science Foundation of China(Grant No.61775223)the Strategic Priority Research Program of Chinese Academy of Sciences(Grant No.XDB1603)
文摘We studied the evolution of wavefront aberration(WFA) of a signal beam during amplification in a Ti:sapphire chirped pulse amplification(CPA) system. The results verified that the WFA of the amplified laser beam has little relation with the change of the pump beam energies. Transverse parasitic lasing that might occur in CPA hardly affects the wavefront of the signal beam. Thermal effects were also considered in this study, and the results show that the thermal effect cumulated in multiple amplification processes also has no obvious influence on the wavefront of the signal beam for a single-shot frequency. The results presented in this paper confirmed experimentally that the amplification in a Ti:sapphire CPA system has little impact on the WFA of the signal beam and it is very helpful for wavefront correction of single-shot PW and multi-PW laser systems based on Ti:sapphire.
基金We are grateful for financial supports from National Key Research and Development Program(Grant No.2017YFA0701200)National Science Foundation of China(No.11704030).The author Z X Feng thanks the valuable discussions with Xu-Jia Wang and Rengmao Wu.
文摘Current freeform illumination optical designs are mostly focused on producing prescribed irradiance distributions on planar targets.Here,we aim to design freeform optics that could generate a desired illumination on a curved target from a point source,which is still a challenge.We reduce the difficulties that arise from the curved target by involving its varying z-coordinates in the iterative wavefront tailoring(IWT)procedure.The new IWT-based method is developed under the stereographic coordinate system with a special mesh transformation of the source domain,which is suitable for light sources with light emissions in semi space such as LED sources.The first example demonstrates that a rectangular flat-top illumination can be generated on an undulating surface by a spherical-freeform lens for a Lambertian source.The second example shows that our method is also applicable for producing a non-uniform irradiance distribution in a circular region of the undulating surface.
