Chinese non-English majors are a large group of English learners.In the process of English pronunciation acquisition,issues such as incomplete phonological knowledge,transfer of mother tongue,and overgeneralization,le...Chinese non-English majors are a large group of English learners.In the process of English pronunciation acquisition,issues such as incomplete phonological knowledge,transfer of mother tongue,and overgeneralization,lead to confusion of phonemes and stress,misunderstanding of syllable structure,and errors of assimilation,drop,and epenthesis.The accuracy of English pronunciation can only be improved by knowing both English and Chinese phonological systems,strengthening the teaching of English phonological knowledge,and adopting various phonological training activities.展开更多
A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)paramet...A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)parametrization was developed to adapt to different experimental sizes.A user-friendly interface was implemented,which allows converting script language expressions into FPGA internal control parameters.The proposed digital system can be combined with a conventional analog data acquisition system to provide more flexibility.The performance of the combined system was veri-fied using experimental data.展开更多
Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst fluid.The most common ...Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst fluid.The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis,which is likely induced by the same pathophysiological mechanisms as after en-doscopic retrograde cholangiopancreatography(ERCP).According to the current European Society of Gastrointestinal Endoscopy guideline,nonsteroidal anti-inflammatory drugs are administered prior to ERCP as a scientifically proven treatment to reduce post-ERCP pancreatitis incidence rate.A single suppository of diclofenac or indomethacin prior to EUS guided tissue acquisition(TA)is harm-less in healthy adults.Since it is associated with low costs and,most important,may prevent a dreadsome complication,we strongly recommend the adminis-tration of 100 mg diclofenac rectally prior to EUS-TA.We will explain this recom-mendation in more detail in this review as well as the risk and pathophysiology of post-EUS TA pancreatitis.展开更多
This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image...This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image.Four new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction results.It is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is used.In future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition performance.Similarity values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%.展开更多
The acquisition of valuable design knowledge from massive fragmentary data is challenging for designers in conceptual product design.This study proposes a novel method for acquiring design knowledge by combining deep ...The acquisition of valuable design knowledge from massive fragmentary data is challenging for designers in conceptual product design.This study proposes a novel method for acquiring design knowledge by combining deep learning with knowledge graph.Specifically,the design knowledge acquisition method utilises the knowledge extraction model to extract design-related entities and relations from fragmentary data,and further constructs the knowledge graph to support design knowledge acquisition for conceptual product design.Moreover,the knowledge extraction model introduces ALBERT to solve memory limitation and communication overhead in the entity extraction module,and uses multi-granularity information to overcome segmentation errors and polysemy ambiguity in the relation extraction module.Experimental comparison verified the effectiveness and accuracy of the proposed knowledge extraction model.The case study demonstrated the feasibility of the knowledge graph construction with real fragmentary porcelain data and showed the capability to provide designers with interconnected and visualised design knowledge.展开更多
As modern electromagnetic environments are more and more complex,the anti-interference performance of the synchronization acquisition is becoming vital in wireless communications.With the rapid development of the digi...As modern electromagnetic environments are more and more complex,the anti-interference performance of the synchronization acquisition is becoming vital in wireless communications.With the rapid development of the digital signal processing technologies,some synchronization acquisition algorithms for hybrid direct-sequence(DS)/frequency hopping(FH)spread spectrum communications have been proposed.However,these algorithms do not focus on the analysis and the design of the synchronization acquisition under typical interferences.In this paper,a synchronization acquisition algorithm based on the frequency hopping pulses combining(FHPC)is proposed.Specifically,the proposed algorithm is composed of two modules:an adaptive interference suppression(IS)module and an adaptive combining decision module.The adaptive IS module mitigates the effect of the interfered samples in the time-domain or the frequencydomain,and the adaptive combining decision module can utilize each frequency hopping pulse to construct an anti-interference decision metric and generate an adaptive acquisition decision threshold to complete the acquisition.Theory and simulation demonstrate that the proposed algorithm significantly enhances the antiinterference and anti-noise performances of the synchronization acquisition for hybrid DS/FH communications.展开更多
In patients with liver tumors,the histopathology examination can assist in diagnosis,staging,prognosis,and therapeutic management strategy.Endoscopic ultrasound(EUS)-guided tissue acquisition using fine needle aspirat...In patients with liver tumors,the histopathology examination can assist in diagnosis,staging,prognosis,and therapeutic management strategy.Endoscopic ultrasound(EUS)-guided tissue acquisition using fine needle aspiration(FNA)or more newly fine needle biopsy(FNB)is a well-developed technique in order to evaluate and differentiate the liver masses.The goal of the EUS-FNA or EUS-FNB is to provide an accurate sample for a histopathology examination.Therefore,malignant tumors such as hepatocarcinoma,cholangiocarcinoma and liver metastasis or benign tumors such as liver adenoma,focal hyperplastic nodular tumors and cystic lesions can be accurately diagnosed using EUS-guided tissue acquisition.EUS-FNB using 19 or 22 Ga needle provide longer samples and a higher diagnostic accuracy in patients with liver masses when compared with EUS-FNA.Few data are available on the diagnostic accuracy of EUS-FNB when compared with percutaneously,ultrasound,computer tomography or transjugulary-guided liver biopsies.This review will discuss the EUS-guided tissue acquisition options in patients with liver tumors and its efficacy and safety in providing accurate samples.The results of the last studies comparing EUS-guided liver biopsy with other conventional techniques are presented.The EUS-guided tissue acquisition using FNB can be a suitable technique in suspected liver lesions in order to provide an accurate histopathology diagnosis,especially for those who require endoscopy.展开更多
This paper delves into the economic event surrounding Intel Corporation’s high-profile acquisition of Tower Corporation.It aims to investigate the reasons behind Intel’s decision to acquire Tower,employ the SWOT ana...This paper delves into the economic event surrounding Intel Corporation’s high-profile acquisition of Tower Corporation.It aims to investigate the reasons behind Intel’s decision to acquire Tower,employ the SWOT analysis method to evaluate the event,and examine its impact on relevant stakeholders.The findings indicate that Intel’s acquisition of Tower was driven by objectives such as strengthening business areas,expanding market share,technological innovation and development,and future development strategy.Through the application of SWOT analysis,it becomes evident that the advantages of the acquisition lie in strengthening technical capabilities and expanding business segments,while simultaneously facing challenges such as integration complexities and pressure.The significance of this paper lies in gaining a comprehensive understanding of the strategic motivations and potential impacts associated with corporate acquisitions,thereby providing valuable insights for decision-making processes.The innovation lies in the comprehensive utilization of SWOT analysis to holistically evaluate the acquisition event,enabling a thorough assessment of its various aspects.For government and policymakers,they should strength regulation of corporate takeovers to ensure fair and transparent market competition,provide support and incentives,and strength cooperation to develop common policies and norms.As for enterprises,it is advised that strategic planning and comprehensive consideration should be formulated and carried out when making acquisitions.Also,stakeholders should actively participate in and monitor the process of corporate acquisition discussion and decision-making,and strengthen cooperation to ensure fair competition,maximizing the interests of all parties.展开更多
In the realm of psychology and language acquisition,the exploration of“individual differences”-encompassing attributes such as personality traits,motivation,and language aptitude-has long been a focal point of schol...In the realm of psychology and language acquisition,the exploration of“individual differences”-encompassing attributes such as personality traits,motivation,and language aptitude-has long been a focal point of scholarly investigation.Within this sphere,the book“Researching Creativity in Second Language Acquisition”by Ashleigh Pipes offers a fresh perspective on the role of creativity as a significant individual difference in Second Language Acquisition(SLA).Positioned against the backdrop of extensive empirical research on individual differences,this book stands out by focusing on the often overlooked aspect of creativity,which Pipes argues,holds paramount importance in SLA.展开更多
Land acquisition is subject of many frauds worldwide. In Africa countries, land acquisition frauds are a real curse. Main reasons of the high land acquisition frauds in Africa are a lack of a reliable land acquisition...Land acquisition is subject of many frauds worldwide. In Africa countries, land acquisition frauds are a real curse. Main reasons of the high land acquisition frauds in Africa are a lack of a reliable land acquisition protocol implementation, no centralized information system that records land transactions and integrates all actors, lack of education about the acquisition protocol and lack of applied sanctions in case of frauds. As of sanctions, the issue is bound to the corruption plague in Africa. Authorities that are supposed to rule the laws are not well paid and are part of the corruption scheme. Most frequent frauds are multiple sales of the same land, falsified land title, false owner identification. In Africa, a land belongs generally to the first residents of the area. To claim ownership of a land, an owner should be recognized by the rural or city authorities. To achieve this recognition, he must obtain from those authorities an attribution letter. The author proposed a complete and reliable land acquisition protocol named ACLAP (Africa Countries Land Acquisition Protocol). The purpose of this paper is to explain the main components of the protocol implementation and show its efficiency when confronting fraud threats. In this paper, a Generic and Reliable Land Acquisition Protocol Implementation in Sub-Saharan Africa countries context is proposed. The platform keeps relevant land transaction information for administrators, managers, buyers, sellers, or for people consultation purpose. The application may be used in village, city, department, region, or country for land management decision making.展开更多
Android smartphones largely dominate the smartphone market. For this reason, it is very important to examine these smartphones in terms of digital forensics since they are often used as evidence in trials. It is possi...Android smartphones largely dominate the smartphone market. For this reason, it is very important to examine these smartphones in terms of digital forensics since they are often used as evidence in trials. It is possible to acquire a physical or logical image of these devices. Acquiring physical and logical images has advantages and disadvantages compared to each other. Creating the logical image is done at the file system level. Analysis can be made on this logical image. Both logical image acquisition and analysis of the image can be done by software tools. In this study, the differences between logical image and physical image acquisition in Android smartphones, their advantages and disadvantages compared to each other, the difficulties that may be encountered in obtaining physical images, which type of image contributes to obtaining more useful and effective data, which one should be preferred for different conditions, and the benefits of having root authority are discussed. The practice of getting the logical image of the Android smartphones and making an analysis on the image is also included. Although root privileges are not required for logical image acquisition, it has been observed that very limited data will be obtained with the logical image created without root privileges. Nevertheless, logical image acquisition has advantages too against physical image acquisition.展开更多
The risk assessment and control of medical investment,merger,and acquisition are crucial topics within the medical industry,encompassing various aspects of investment,merger,and acquisition within this sector.The proc...The risk assessment and control of medical investment,merger,and acquisition are crucial topics within the medical industry,encompassing various aspects of investment,merger,and acquisition within this sector.The process primarily targets the unique nature and associated risks of the medical industry,focusing on effective risk management and control strategies to facilitate the smooth progression of investment,merger,and acquisition activities.展开更多
The teaching of English speeches in universities aims to enhance oral communication ability,improve English communication skills,and expand English knowledge,occupying a core position in English teaching in universiti...The teaching of English speeches in universities aims to enhance oral communication ability,improve English communication skills,and expand English knowledge,occupying a core position in English teaching in universities.This article takes the theory of second language acquisition as the background,analyzes the important role and value of this theory in English speech teaching in universities,and explores how to apply the theory of second language acquisition in English speech teaching in universities.It aims to strengthen the cultivation of English skilled talents and provide a brief reference for improving English speech teaching in universities.展开更多
A control and data acquisition system was implemented for the recently developed collinear laser spectroscopy setup.This system is dedicated to data recording,storage,processing,monitoring of the beam intensity and en...A control and data acquisition system was implemented for the recently developed collinear laser spectroscopy setup.This system is dedicated to data recording,storage,processing,monitoring of the beam intensity and energy,and visualization of various spectra.In comparison to the conventional resonance nuclear reaction system,the key technique is the precise synchronization of the detected counts with the actual scanning voltage(or probing laser frequency).The functions of the system were tested by measuring the hyperfine structure spectra of stable calcium(e.g.,^(40)Ca^(+))and radioactive potassium(e.g.,^(38)K)in the bunched and continuous modes,respectively.This system will be routinely applied and further improved in subsequent laser spectroscopy experiments on unstable isotopes at the Beijing Radioactive Ion-beam Facility(BRIF).展开更多
As high-dynamics and weak-signal are of two primary concerns of navigation using Global Navigation Satellite System(GNSS)signals,an acquisition algorithm based on threetime fractional Fourier transform(FRFT)is present...As high-dynamics and weak-signal are of two primary concerns of navigation using Global Navigation Satellite System(GNSS)signals,an acquisition algorithm based on threetime fractional Fourier transform(FRFT)is presented to simplify the calculation effectively.Firstly,the correlation results similar to linear frequency modulated(LFM)signals are derived on the basis of the high dynamic GNSS signal model.Then,the principle of obtaining the optimum rotation angle is analyzed,which is measured by FRFT projection lengths with two selected rotation angles.Finally,Doppler shift,Doppler rate,and code phase are accurately estimated in a real-time and low signal to noise ratio(SNR)wireless communication system.The theoretical analysis and simulation results show that the fast FRFT algorithm can accurately estimate the high dynamic parameters by converting the traditional two-dimensional search process to only three times FRFT.While the acquisition performance is basically the same,the computational complexity and running time are greatly reduced,which is more conductive to practical application.展开更多
Aim: To observe the rats’ learning and memory acquisition ability disturbance induced by BI-D1870. Methods: Male SD rats were randomly divided into control group, solvent control group and BI-D1870 group. The rats in...Aim: To observe the rats’ learning and memory acquisition ability disturbance induced by BI-D1870. Methods: Male SD rats were randomly divided into control group, solvent control group and BI-D1870 group. The rats in the control group were intraperitoneally injected with saline, while those in the solvent control group were intraperitoneally injected with DMSO + sulfobutyl-β-cyclodextrin solvent, and those in the BI-D1870 group were intraperitoneally injected with BI-D1870. All the rats’ appearance and behavior were daily observed, and body weight was recorded on the day 15, 30, 45, 60, 75 and 82 of BI-D1870 injected. Morris water maze was used to screen the rats’ learning and memory acquisition ability on the day 22 - 25, 52 - 55, and 82 - 85 of training by BI-D1870 treated. The successful rates of the rats’ memory impairment were respectively calculated for three times screening. Results: During the whole experiment, there was no obvious difference in appearance and fur color in all rats. The rats’ agitation began to appear on the day 10th of BI-D1870 given. The agitation rats’ number and rats’ body weight gradually increased along with BI-D1870 treated (P P Conclusion: Intraperitoneal injection of BI-D1870 can induce the rats’ learning and memory acquisition ability disorder.展开更多
Low Earth Orbit(LEO)satellite communications can provide global coverage in the sixth generation communication(6G)networks.To combat the strong Partial Band Interferences(PBIs)and multipath fading in LEO satellite com...Low Earth Orbit(LEO)satellite communications can provide global coverage in the sixth generation communication(6G)networks.To combat the strong Partial Band Interferences(PBIs)and multipath fading in LEO satellite communication systems,the Multicarrier Direct Sequence Code Division Multiple Access(MC-DS-CDMA)technique is a promising alternative to the traditional Single-carrier Direct Sequence Code Division Multiple Access(SC-DS-CDMA)system for its advantages of high bandwidth efficiency,superior interference rejection capability,and low complexity of parallel signal processing.However,limited studies have been conducted on the performance analysis of MC-DS-CDMA acquisition systems in the presence of a large Doppler shift,a unique characteristic of LEO satellite communications.To bridge this gap,we investigate the performance of MC-DS-CDMA systems with two-dimensional acquisition and noncoherent equal gain combining over Rician fading channel in the presence of the Doppler shift and PBIs.The performance metrics are detection probability and Mean Square Error(MSE)of the Doppler factor and delay.Specifically,we derive the closed-form expressions for the MSE and the Probability Density Function(PDF)of the acquisition decision variable and obtain the detection probability.We conduct extensive numerical experiments to verify the theoretical analysis and performance gain of MC-DSCDMA over the SC-DS-CDMA.The results show that MC-DS-CDMA with two-dimensional acquisition is more robust to multipath Rician fading than SC-DS-CDMA.Moreover,MC-DS-CDMA outperforms SC-DS-CDMA regarding the detection probability and MSE when combating the strong PBIs.展开更多
In this study,we analyze the stock market reaction to 35 events associated with 32 publicly traded companies from six countries that have announced cryptocurrency acquisitions,selling,or acceptance as a means of payme...In this study,we analyze the stock market reaction to 35 events associated with 32 publicly traded companies from six countries that have announced cryptocurrency acquisitions,selling,or acceptance as a means of payment.Our analysis focuses on traditional firms whose core business is unrelated to blockchain or cryptocurrency.We find that the aggregate market reaction around these events is slightly positive but statistically insignificant for most event windows.However,when we perform heterogeneity analyses,we observe significant differences in market reaction between events with high(larger CARs)and low cryptocurrency exposure(lower CARs).Multivariate regressions show that the level of exposure to cryptocurrency("skin in the game")is a critical factor underlying abnormal returns around the event.Further analyses reveal that economically meaningful acquisitions of BTC or ETH(relative to firm’s total assets)drive the observed effect.Our findings have important implications for managers,investors,and analysts as they shed light on the relationship between cryptocurrency adoption and firm value.展开更多
Pancreatic ductal adenocarcinoma is speculated to become the second leading cause of cancer-related mortality by 2030,a high mortality rate considering the number of cases.Surgery and chemotherapy are the main treatme...Pancreatic ductal adenocarcinoma is speculated to become the second leading cause of cancer-related mortality by 2030,a high mortality rate considering the number of cases.Surgery and chemotherapy are the main treatment options,but they are burdensome for patients.A clear histological diagnosis is needed to determine a treatment plan,and endoscopic ultrasound(EUS)-guided tissue acquisition(TA)is a suitable technique that does not worsen the cancer-specific prognosis even for lesions at risk of needle tract seeding.With the development of personalized medicine and precision treatment,there has been an increasing demand to increase cell counts and collect specimens while preserving tissue structure,leading to the development of the fine-needle biopsy(FNB)needle.EUS-FNB is rapidly replacing EUS-guided fine-needle aspiration(FNA)as the procedure of choice for EUS-TA of pancreatic cancer.However,EUS-FNA is sometimes necessary where the FNB needle cannot penetrate small hard lesions,so it is important clinicians are familiar with both.Given these recent developments,we present an up-to-date review of the role of EUS-TA in pancreatic cancer.Particularly,technical aspects,such as needle caliber,negative pressure,and puncture methods,for obtaining an adequate specimen in EUS-TA are discussed.展开更多
Monitoring of host cell proteins(HCPs)during the manufacturing of monoclonal antibodies(mAb)has become a critical requirement to provide effective and safe drug products.Enzyme-linked immunosorbent assays are still th...Monitoring of host cell proteins(HCPs)during the manufacturing of monoclonal antibodies(mAb)has become a critical requirement to provide effective and safe drug products.Enzyme-linked immunosorbent assays are still the gold standard methods for the quantification of protein impurities.However,this technique has several limitations and does,among others,not enable the precise identification of proteins.In this context,mass spectrometry(MS)became an alternative and orthogonal method that delivers qualitative and quantitative information on all identified HCPs.However,in order to be routinely implemented in biopharmaceutical companies,liquid chromatography-MS based methods still need to be standardized to provide highest sensitivity and robust and accurate quantification.Here,we present a promising MS-based analytical workflow coupling the use of an innovative quantification standard,the HCP Profiler solution,with a spectral library-based data-independent acquisition(DIA)method and strict data validation criteria.The performances of the HCP Profiler solution were compared to more conventional standard protein spikes and the DIA approach was benchmarked against a classical datadependent acquisition on a series of samples produced at various stages of the manufacturing process.While we also explored spectral library-free DIA interpretation,the spectral library-based approach still showed highest accuracy and reproducibility(coefficients of variation<10%)with a sensitivity down to the sub-ng/mg mAb level.Thus,this workflow is today mature to be used as a robust and straightforward method to support mAb manufacturing process developments and drug products quality control.展开更多
文摘Chinese non-English majors are a large group of English learners.In the process of English pronunciation acquisition,issues such as incomplete phonological knowledge,transfer of mother tongue,and overgeneralization,lead to confusion of phonemes and stress,misunderstanding of syllable structure,and errors of assimilation,drop,and epenthesis.The accuracy of English pronunciation can only be improved by knowing both English and Chinese phonological systems,strengthening the teaching of English phonological knowledge,and adopting various phonological training activities.
基金This work was supported by the National Key R&D Program of China(Nos.2023YFA1606403 and 2023YFE0101600)the National Natural Science Foundation of China(Nos.12027809,11961141003,U1967201,11875073 and 11875074).
文摘A digital data-acquisition system based on XIA LLC products was used in a complex nuclear reaction experiment using radioactive ion beams.A flexible trigger system based on a field-programmable gate array(FPGA)parametrization was developed to adapt to different experimental sizes.A user-friendly interface was implemented,which allows converting script language expressions into FPGA internal control parameters.The proposed digital system can be combined with a conventional analog data acquisition system to provide more flexibility.The performance of the combined system was veri-fied using experimental data.
文摘Endoscopic ultrasound(EUS)with fine needle aspiration or fine needle biopsy is the gold standard for sampling tissue to diagnose pancreatic cancer and auto-immune pancreatitis or to analyze cyst fluid.The most common reported adverse event of fine needle aspiration and/or fine needle biopsy is acute pancreatitis,which is likely induced by the same pathophysiological mechanisms as after en-doscopic retrograde cholangiopancreatography(ERCP).According to the current European Society of Gastrointestinal Endoscopy guideline,nonsteroidal anti-inflammatory drugs are administered prior to ERCP as a scientifically proven treatment to reduce post-ERCP pancreatitis incidence rate.A single suppository of diclofenac or indomethacin prior to EUS guided tissue acquisition(TA)is harm-less in healthy adults.Since it is associated with low costs and,most important,may prevent a dreadsome complication,we strongly recommend the adminis-tration of 100 mg diclofenac rectally prior to EUS-TA.We will explain this recom-mendation in more detail in this review as well as the risk and pathophysiology of post-EUS TA pancreatitis.
文摘This paper presents an investigation on the effect of JPEG compression on the similarity between the target image and the background,where the similarity is further used to determine the degree of clutter in the image.Four new clutter metrics based on image quality assessment are introduced,among which the Haar wavelet-based perceptual similarity index,known as HaarPSI,provides the best target acquisition prediction results.It is shown that the similarity between the target and the background at the boundary between visually lossless and visually lossy compression does not change significantly compared to the case when an uncompressed image is used.In future work,through subjective tests,it is necessary to check whether this presence of compression at the threshold of just noticeable differences will affect the human target acquisition performance.Similarity values are compared with the results of subjective tests of the well-known target Search_2 database,where the degree of agreement between objective and subjective scores,measured through linear correlation,reached a value of 90%.
基金This research is supported by the Chinese Special Projects of the National Key Research and Development Plan(2019YFB1405702).
文摘The acquisition of valuable design knowledge from massive fragmentary data is challenging for designers in conceptual product design.This study proposes a novel method for acquiring design knowledge by combining deep learning with knowledge graph.Specifically,the design knowledge acquisition method utilises the knowledge extraction model to extract design-related entities and relations from fragmentary data,and further constructs the knowledge graph to support design knowledge acquisition for conceptual product design.Moreover,the knowledge extraction model introduces ALBERT to solve memory limitation and communication overhead in the entity extraction module,and uses multi-granularity information to overcome segmentation errors and polysemy ambiguity in the relation extraction module.Experimental comparison verified the effectiveness and accuracy of the proposed knowledge extraction model.The case study demonstrated the feasibility of the knowledge graph construction with real fragmentary porcelain data and showed the capability to provide designers with interconnected and visualised design knowledge.
基金supported in part by the National Natural Science Foundation of China (NSFC) under Grants 62131005, 62071096in part by the Fundamental Research Funds for the Central Universities under Grant 2242022k60006+1 种基金in part by the National NSFC under Grant U19B2014in part by the Natural Science Foundation of Sichuan under Grant 2022NSFSC0495
文摘As modern electromagnetic environments are more and more complex,the anti-interference performance of the synchronization acquisition is becoming vital in wireless communications.With the rapid development of the digital signal processing technologies,some synchronization acquisition algorithms for hybrid direct-sequence(DS)/frequency hopping(FH)spread spectrum communications have been proposed.However,these algorithms do not focus on the analysis and the design of the synchronization acquisition under typical interferences.In this paper,a synchronization acquisition algorithm based on the frequency hopping pulses combining(FHPC)is proposed.Specifically,the proposed algorithm is composed of two modules:an adaptive interference suppression(IS)module and an adaptive combining decision module.The adaptive IS module mitigates the effect of the interfered samples in the time-domain or the frequencydomain,and the adaptive combining decision module can utilize each frequency hopping pulse to construct an anti-interference decision metric and generate an adaptive acquisition decision threshold to complete the acquisition.Theory and simulation demonstrate that the proposed algorithm significantly enhances the antiinterference and anti-noise performances of the synchronization acquisition for hybrid DS/FH communications.
文摘In patients with liver tumors,the histopathology examination can assist in diagnosis,staging,prognosis,and therapeutic management strategy.Endoscopic ultrasound(EUS)-guided tissue acquisition using fine needle aspiration(FNA)or more newly fine needle biopsy(FNB)is a well-developed technique in order to evaluate and differentiate the liver masses.The goal of the EUS-FNA or EUS-FNB is to provide an accurate sample for a histopathology examination.Therefore,malignant tumors such as hepatocarcinoma,cholangiocarcinoma and liver metastasis or benign tumors such as liver adenoma,focal hyperplastic nodular tumors and cystic lesions can be accurately diagnosed using EUS-guided tissue acquisition.EUS-FNB using 19 or 22 Ga needle provide longer samples and a higher diagnostic accuracy in patients with liver masses when compared with EUS-FNA.Few data are available on the diagnostic accuracy of EUS-FNB when compared with percutaneously,ultrasound,computer tomography or transjugulary-guided liver biopsies.This review will discuss the EUS-guided tissue acquisition options in patients with liver tumors and its efficacy and safety in providing accurate samples.The results of the last studies comparing EUS-guided liver biopsy with other conventional techniques are presented.The EUS-guided tissue acquisition using FNB can be a suitable technique in suspected liver lesions in order to provide an accurate histopathology diagnosis,especially for those who require endoscopy.
文摘This paper delves into the economic event surrounding Intel Corporation’s high-profile acquisition of Tower Corporation.It aims to investigate the reasons behind Intel’s decision to acquire Tower,employ the SWOT analysis method to evaluate the event,and examine its impact on relevant stakeholders.The findings indicate that Intel’s acquisition of Tower was driven by objectives such as strengthening business areas,expanding market share,technological innovation and development,and future development strategy.Through the application of SWOT analysis,it becomes evident that the advantages of the acquisition lie in strengthening technical capabilities and expanding business segments,while simultaneously facing challenges such as integration complexities and pressure.The significance of this paper lies in gaining a comprehensive understanding of the strategic motivations and potential impacts associated with corporate acquisitions,thereby providing valuable insights for decision-making processes.The innovation lies in the comprehensive utilization of SWOT analysis to holistically evaluate the acquisition event,enabling a thorough assessment of its various aspects.For government and policymakers,they should strength regulation of corporate takeovers to ensure fair and transparent market competition,provide support and incentives,and strength cooperation to develop common policies and norms.As for enterprises,it is advised that strategic planning and comprehensive consideration should be formulated and carried out when making acquisitions.Also,stakeholders should actively participate in and monitor the process of corporate acquisition discussion and decision-making,and strengthen cooperation to ensure fair competition,maximizing the interests of all parties.
文摘In the realm of psychology and language acquisition,the exploration of“individual differences”-encompassing attributes such as personality traits,motivation,and language aptitude-has long been a focal point of scholarly investigation.Within this sphere,the book“Researching Creativity in Second Language Acquisition”by Ashleigh Pipes offers a fresh perspective on the role of creativity as a significant individual difference in Second Language Acquisition(SLA).Positioned against the backdrop of extensive empirical research on individual differences,this book stands out by focusing on the often overlooked aspect of creativity,which Pipes argues,holds paramount importance in SLA.
文摘Land acquisition is subject of many frauds worldwide. In Africa countries, land acquisition frauds are a real curse. Main reasons of the high land acquisition frauds in Africa are a lack of a reliable land acquisition protocol implementation, no centralized information system that records land transactions and integrates all actors, lack of education about the acquisition protocol and lack of applied sanctions in case of frauds. As of sanctions, the issue is bound to the corruption plague in Africa. Authorities that are supposed to rule the laws are not well paid and are part of the corruption scheme. Most frequent frauds are multiple sales of the same land, falsified land title, false owner identification. In Africa, a land belongs generally to the first residents of the area. To claim ownership of a land, an owner should be recognized by the rural or city authorities. To achieve this recognition, he must obtain from those authorities an attribution letter. The author proposed a complete and reliable land acquisition protocol named ACLAP (Africa Countries Land Acquisition Protocol). The purpose of this paper is to explain the main components of the protocol implementation and show its efficiency when confronting fraud threats. In this paper, a Generic and Reliable Land Acquisition Protocol Implementation in Sub-Saharan Africa countries context is proposed. The platform keeps relevant land transaction information for administrators, managers, buyers, sellers, or for people consultation purpose. The application may be used in village, city, department, region, or country for land management decision making.
文摘Android smartphones largely dominate the smartphone market. For this reason, it is very important to examine these smartphones in terms of digital forensics since they are often used as evidence in trials. It is possible to acquire a physical or logical image of these devices. Acquiring physical and logical images has advantages and disadvantages compared to each other. Creating the logical image is done at the file system level. Analysis can be made on this logical image. Both logical image acquisition and analysis of the image can be done by software tools. In this study, the differences between logical image and physical image acquisition in Android smartphones, their advantages and disadvantages compared to each other, the difficulties that may be encountered in obtaining physical images, which type of image contributes to obtaining more useful and effective data, which one should be preferred for different conditions, and the benefits of having root authority are discussed. The practice of getting the logical image of the Android smartphones and making an analysis on the image is also included. Although root privileges are not required for logical image acquisition, it has been observed that very limited data will be obtained with the logical image created without root privileges. Nevertheless, logical image acquisition has advantages too against physical image acquisition.
文摘The risk assessment and control of medical investment,merger,and acquisition are crucial topics within the medical industry,encompassing various aspects of investment,merger,and acquisition within this sector.The process primarily targets the unique nature and associated risks of the medical industry,focusing on effective risk management and control strategies to facilitate the smooth progression of investment,merger,and acquisition activities.
文摘The teaching of English speeches in universities aims to enhance oral communication ability,improve English communication skills,and expand English knowledge,occupying a core position in English teaching in universities.This article takes the theory of second language acquisition as the background,analyzes the important role and value of this theory in English speech teaching in universities,and explores how to apply the theory of second language acquisition in English speech teaching in universities.It aims to strengthen the cultivation of English skilled talents and provide a brief reference for improving English speech teaching in universities.
基金supported by the National Natural Science Foundation of China (Nos.12027809,U1967201,11875073,11875074 and 11961141003)National Key R&D Program of China (No.2018YFA0404403)the State Key Laboratory of Nuclear Physics and Technology,Peking University (Nos.NPT2019ZZ02,NPT2020KFY17).
文摘A control and data acquisition system was implemented for the recently developed collinear laser spectroscopy setup.This system is dedicated to data recording,storage,processing,monitoring of the beam intensity and energy,and visualization of various spectra.In comparison to the conventional resonance nuclear reaction system,the key technique is the precise synchronization of the detected counts with the actual scanning voltage(or probing laser frequency).The functions of the system were tested by measuring the hyperfine structure spectra of stable calcium(e.g.,^(40)Ca^(+))and radioactive potassium(e.g.,^(38)K)in the bunched and continuous modes,respectively.This system will be routinely applied and further improved in subsequent laser spectroscopy experiments on unstable isotopes at the Beijing Radioactive Ion-beam Facility(BRIF).
基金supported by Shenzhen Science and Technology Program(JCYJ20180508152046428).
文摘As high-dynamics and weak-signal are of two primary concerns of navigation using Global Navigation Satellite System(GNSS)signals,an acquisition algorithm based on threetime fractional Fourier transform(FRFT)is presented to simplify the calculation effectively.Firstly,the correlation results similar to linear frequency modulated(LFM)signals are derived on the basis of the high dynamic GNSS signal model.Then,the principle of obtaining the optimum rotation angle is analyzed,which is measured by FRFT projection lengths with two selected rotation angles.Finally,Doppler shift,Doppler rate,and code phase are accurately estimated in a real-time and low signal to noise ratio(SNR)wireless communication system.The theoretical analysis and simulation results show that the fast FRFT algorithm can accurately estimate the high dynamic parameters by converting the traditional two-dimensional search process to only three times FRFT.While the acquisition performance is basically the same,the computational complexity and running time are greatly reduced,which is more conductive to practical application.
文摘Aim: To observe the rats’ learning and memory acquisition ability disturbance induced by BI-D1870. Methods: Male SD rats were randomly divided into control group, solvent control group and BI-D1870 group. The rats in the control group were intraperitoneally injected with saline, while those in the solvent control group were intraperitoneally injected with DMSO + sulfobutyl-β-cyclodextrin solvent, and those in the BI-D1870 group were intraperitoneally injected with BI-D1870. All the rats’ appearance and behavior were daily observed, and body weight was recorded on the day 15, 30, 45, 60, 75 and 82 of BI-D1870 injected. Morris water maze was used to screen the rats’ learning and memory acquisition ability on the day 22 - 25, 52 - 55, and 82 - 85 of training by BI-D1870 treated. The successful rates of the rats’ memory impairment were respectively calculated for three times screening. Results: During the whole experiment, there was no obvious difference in appearance and fur color in all rats. The rats’ agitation began to appear on the day 10th of BI-D1870 given. The agitation rats’ number and rats’ body weight gradually increased along with BI-D1870 treated (P P Conclusion: Intraperitoneal injection of BI-D1870 can induce the rats’ learning and memory acquisition ability disorder.
基金supported by the State Key Program of NSFC(No.U1836201)and NSFC(No.92038302).
文摘Low Earth Orbit(LEO)satellite communications can provide global coverage in the sixth generation communication(6G)networks.To combat the strong Partial Band Interferences(PBIs)and multipath fading in LEO satellite communication systems,the Multicarrier Direct Sequence Code Division Multiple Access(MC-DS-CDMA)technique is a promising alternative to the traditional Single-carrier Direct Sequence Code Division Multiple Access(SC-DS-CDMA)system for its advantages of high bandwidth efficiency,superior interference rejection capability,and low complexity of parallel signal processing.However,limited studies have been conducted on the performance analysis of MC-DS-CDMA acquisition systems in the presence of a large Doppler shift,a unique characteristic of LEO satellite communications.To bridge this gap,we investigate the performance of MC-DS-CDMA systems with two-dimensional acquisition and noncoherent equal gain combining over Rician fading channel in the presence of the Doppler shift and PBIs.The performance metrics are detection probability and Mean Square Error(MSE)of the Doppler factor and delay.Specifically,we derive the closed-form expressions for the MSE and the Probability Density Function(PDF)of the acquisition decision variable and obtain the detection probability.We conduct extensive numerical experiments to verify the theoretical analysis and performance gain of MC-DSCDMA over the SC-DS-CDMA.The results show that MC-DS-CDMA with two-dimensional acquisition is more robust to multipath Rician fading than SC-DS-CDMA.Moreover,MC-DS-CDMA outperforms SC-DS-CDMA regarding the detection probability and MSE when combating the strong PBIs.
基金National Council for Scientific and Technological Development–CNPq(Grant#313033/2022-6)and the Silicon Valley Community Foundation for providing financial support to conduct this research throughout the University Blockchain Research Initiative(UBRI).
文摘In this study,we analyze the stock market reaction to 35 events associated with 32 publicly traded companies from six countries that have announced cryptocurrency acquisitions,selling,or acceptance as a means of payment.Our analysis focuses on traditional firms whose core business is unrelated to blockchain or cryptocurrency.We find that the aggregate market reaction around these events is slightly positive but statistically insignificant for most event windows.However,when we perform heterogeneity analyses,we observe significant differences in market reaction between events with high(larger CARs)and low cryptocurrency exposure(lower CARs).Multivariate regressions show that the level of exposure to cryptocurrency("skin in the game")is a critical factor underlying abnormal returns around the event.Further analyses reveal that economically meaningful acquisitions of BTC or ETH(relative to firm’s total assets)drive the observed effect.Our findings have important implications for managers,investors,and analysts as they shed light on the relationship between cryptocurrency adoption and firm value.
文摘Pancreatic ductal adenocarcinoma is speculated to become the second leading cause of cancer-related mortality by 2030,a high mortality rate considering the number of cases.Surgery and chemotherapy are the main treatment options,but they are burdensome for patients.A clear histological diagnosis is needed to determine a treatment plan,and endoscopic ultrasound(EUS)-guided tissue acquisition(TA)is a suitable technique that does not worsen the cancer-specific prognosis even for lesions at risk of needle tract seeding.With the development of personalized medicine and precision treatment,there has been an increasing demand to increase cell counts and collect specimens while preserving tissue structure,leading to the development of the fine-needle biopsy(FNB)needle.EUS-FNB is rapidly replacing EUS-guided fine-needle aspiration(FNA)as the procedure of choice for EUS-TA of pancreatic cancer.However,EUS-FNA is sometimes necessary where the FNB needle cannot penetrate small hard lesions,so it is important clinicians are familiar with both.Given these recent developments,we present an up-to-date review of the role of EUS-TA in pancreatic cancer.Particularly,technical aspects,such as needle caliber,negative pressure,and puncture methods,for obtaining an adequate specimen in EUS-TA are discussed.
基金supported by the“Association Nationale de la Recherche et de la Technologie”and UCB Pharma S.A.(Belgium and France)via the CIFRE fellowship of Steve Hessmannsupported by the“Agence Nationale de la Recherche”via the French Proteomic Infrastructure ProFI FR2048(ANR-10-INBS-08-03).
文摘Monitoring of host cell proteins(HCPs)during the manufacturing of monoclonal antibodies(mAb)has become a critical requirement to provide effective and safe drug products.Enzyme-linked immunosorbent assays are still the gold standard methods for the quantification of protein impurities.However,this technique has several limitations and does,among others,not enable the precise identification of proteins.In this context,mass spectrometry(MS)became an alternative and orthogonal method that delivers qualitative and quantitative information on all identified HCPs.However,in order to be routinely implemented in biopharmaceutical companies,liquid chromatography-MS based methods still need to be standardized to provide highest sensitivity and robust and accurate quantification.Here,we present a promising MS-based analytical workflow coupling the use of an innovative quantification standard,the HCP Profiler solution,with a spectral library-based data-independent acquisition(DIA)method and strict data validation criteria.The performances of the HCP Profiler solution were compared to more conventional standard protein spikes and the DIA approach was benchmarked against a classical datadependent acquisition on a series of samples produced at various stages of the manufacturing process.While we also explored spectral library-free DIA interpretation,the spectral library-based approach still showed highest accuracy and reproducibility(coefficients of variation<10%)with a sensitivity down to the sub-ng/mg mAb level.Thus,this workflow is today mature to be used as a robust and straightforward method to support mAb manufacturing process developments and drug products quality control.
