Objective:To explore the main acupoint prescription and mechanism of acupuncture in treating Functional dyspepsia(FD)by analyzing the clinical randomized controlled trial literature on acupoints and targets of acupunc...Objective:To explore the main acupoint prescription and mechanism of acupuncture in treating Functional dyspepsia(FD)by analyzing the clinical randomized controlled trial literature on acupoints and targets of acupuncture in the treatment of FD combined with association rule mining and bioinformatics/network pharmacology methods.Methods:Search relevant clinical randomized controlled trial literature on acupoints and therapeutic targets of acupuncture in the treatment of FD from eight databases from their inception to June 18th,2022.We obtained acupuncture selection points,meridian,and therapeutic targets and established acupoints database for acupuncture treatment of FD.FD-related targets were collected from GeneCards,DisGeNET,OMIM,and DrugBank databases.We obtained the potential targets of acupuncture on FD by taking the intersection of acupuncture for FD therapeutic targets and FD-related targets.We performed the protein-protein interaction network,Gene Ontology(GO)analysis,and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis.Results:In this study,26 Randomized Controlled Trials related to acupuncture treatment of FD were retrieved.We obtained 29 acupoints,17 acupuncture for FD therapeutic targets,and 10 intersection targets.Tumor necrosis factor(TNF),Interleukin(IL)-1,and Neuropeptide Y(NPY)are key targets of acupuncture in the treatment of FD.Conclusion:ST36-CV12-PC6-LR3 is the main acupoint prescription for FD.Acupuncture may affect Neuroactive ligand-receptor interaction,Gastric acid secretion,and IL-17,TNF signaling pathways by regulating related key targets,and play a synergistic role in the treatment of FD by inhibiting gastric acid secretion,alleviating inflammatory response,regulating the brain-gut axis,improving mood and other aspects.展开更多
Inflammatory arthritis refers to the migration of inflammatory cells(such as monocytes/macrophages,lymphocytes,and granulocytes)from the blood to the synovium or synovial fluid,causing joint pain and swelling.It is of...Inflammatory arthritis refers to the migration of inflammatory cells(such as monocytes/macrophages,lymphocytes,and granulocytes)from the blood to the synovium or synovial fluid,causing joint pain and swelling.It is often associated with decreased joint mobility and functional damage.Some diseases lead to cartilage and skeletal damage,resulting in joint destruction.Common inflammatory arthritis includes rheumatoid arthritis,ankylosing spondylitis,and gout.展开更多
Acne is a chronic inflammatory skin disease involving hair follicle sebaceous glands,which is characterized by acne,papules,pustules,nodules,cysts and so on.The disorder of immune inflammation is the key link.A variet...Acne is a chronic inflammatory skin disease involving hair follicle sebaceous glands,which is characterized by acne,papules,pustules,nodules,cysts and so on.The disorder of immune inflammation is the key link.A variety of factors participate in the immune inflammatory response of acne and interact with each other,leading to the occurrence and development of acne inflammation.Acupuncture can regulate the immune and inflammatory response through many links and improve the skin lesions.This study explains potential mechanisms of acupuncture in the treatment of acne by regulating the body's immune inflammatory response,in order to provide new ideas.展开更多
This study was carried out in 120 patients affected by migraine without aura, treated in 4 public health centers and randomly divided into acupuncture group (AG) and conventional drug therapy group (CDTG).
Th... This study was carried out in 120 patients affected by migraine without aura, treated in 4 public health centers and randomly divided into acupuncture group (AG) and conventional drug therapy group (CDTG).
The evaluation of clinical results was made 6 and 12 months after the beginning of treatment and was worked out as well according to socio-medical parameters. Acupuncture was applied to the following points: Touwei (ST 8), Xuanlu (GB 5), Fengchi (GB 20), Dazhui (GV 14), Lieque (LU 7), treated with the reducing method. In AG, the figure scoring the entity and frequency of migraine attacks drops from 9,823 before treatment to 1,990 6 months after and 1,590 12 months after; while in CDTG, it drops from 8,405 before treatment to 3,927 6 months after and 3,084 12 months after. In AG, the total absence from work amounted to 1,120 working days/year, with a total cost (private + social costs) of 186,677,000 Italian liras. In CDTG, the absence from work amounted to 1,404 working days/year, with a total cost of 266,614,000 Italian liras.
If we consider that in Italy the patients affected by migraine without aura are around 800,000, and that acupuncture therapy is able to save 1,332,000 Italian liras on the total average cost supported for every single patient, the application of acupuncture in the treatment of migraine without aura would allow a saving of the health expenses in Italy of over 1,000 billion liras.展开更多
Hyperplasia of mammary glands is a common disease in the middle-aged women, and it is a precancerous lesion of mammary glands. For many years, the author has used Rugen (ST 18) of the Stomach Meridian of Foot-Yang... Hyperplasia of mammary glands is a common disease in the middle-aged women, and it is a precancerous lesion of mammary glands. For many years, the author has used Rugen (ST 18) of the Stomach Meridian of Foot-Yangming as the main point withcertain auxiliary points chosen on basis of the differentiation types to treat the disease and obtained satisfactory therapeutic effects. A report follows.
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Yan Si Xue(咽四穴)refer to four points in the throat summarized by Prof.Sheng Canruo in his long-year clinical experience based on the combination of TCM theory and the knowledge of modernmedical anatomy.By taking “Y...Yan Si Xue(咽四穴)refer to four points in the throat summarized by Prof.Sheng Canruo in his long-year clinical experience based on the combination of TCM theory and the knowledge of modernmedical anatomy.By taking “Yan Si Xue” as main points,and other differential adjunct points,Prof.Sheng has obtained satisfactory therapeutic results in treating various throat diseases such ashoarseness,paralysis of vocal cord,dysphonia after radiotherapy on throat tumor,vocal nodules,disorder of the glossopharyngeal nerve,hysteric aphasia,and acute or chronic laryngopharyngitis.展开更多
Case HistoryName:Kerstin Wiest;Sex:female;Age:46 years;Occupation:teacher;Date of firstvisit:April,1996.Chief complaint:Allergic rhinitis for fiveyears.The patient stated that five years before,she got the sensation o...Case HistoryName:Kerstin Wiest;Sex:female;Age:46 years;Occupation:teacher;Date of firstvisit:April,1996.Chief complaint:Allergic rhinitis for fiveyears.The patient stated that five years before,she got the sensation of weakness and lassitudeafter undergoing a uterectomy,which展开更多
Depressive syndrome is a common complication in cerebral vascular accidents (CVA), which accounts for 70% of the complications. A mild case of the syndrome is marked by grief, sleeping disturbance, weakened mental act...Depressive syndrome is a common complication in cerebral vascular accidents (CVA), which accounts for 70% of the complications. A mild case of the syndrome is marked by grief, sleeping disturbance, weakened mental activities, worry, loss of interest, and irritability. A severe case may have worse symptoms and signs, except the above mentioned ones, such as anxiety, reduced appetite, hallucination, delusion, desperation, etc. The author has adopted acupuncture to treat depressive syndromes after CVA with good therapeutic result as reported in the following.展开更多
Dizziness and vertigo is a commonly encountered disease in clinic. There has been the saying from ancient times that "there would be no dizziness if without wind", " there would be no dizziness if witho...Dizziness and vertigo is a commonly encountered disease in clinic. There has been the saying from ancient times that "there would be no dizziness if without wind", " there would be no dizziness if without phlegm", "there would be no dizziness if without deficiency", and " there would be no dizziness if without fire". However, in the author's view, the dizziness and vertigo caused by blood stasis blocking the collaterals is most commonly seen in clinic, which should deserve more attention. The following is an introduction about the author's experience in treating 3 cases of dizziness and vertigo with acupuncture.展开更多
In recent years, the author has treated 57 cases of hiccup due to radiotherapy, chemotherapy or introducing therapy by acupuncture with satisfactory results as reported in the following.
Objective:To evaluate the structural changes of atherosclerotic plaque before and after acupuncture treatment by three-dimensional ultrasound of Vascular Plaque Quantification technology.Methods:Forty subjects were re...Objective:To evaluate the structural changes of atherosclerotic plaque before and after acupuncture treatment by three-dimensional ultrasound of Vascular Plaque Quantification technology.Methods:Forty subjects were recruited and randomly divided into acupuncture group and sham acupuncture group.All patients were treated twice a week for 3 months and were observed the changes of the bilateral carotid plaque volume(PV),gray scale value(GSM)and inner media thickness(IMT).Results:The acupuncture group’s PV decreased after 3 months,while the sham group’s increased slightly.The result were statistically significant(P≤0.05).After treatment,the acupuncture group’s left GSM was higher than before,while the sham group’s was slightly lower than before.The result were statistically significant(P≤0.05).Although the difference of the acupuncture group’s right GSM before and after treatment was not statistically significant,it also had a rising trend.Conclusion:Acupuncture can reduce the volume of carotid atherosclerotic plaque and stabilize the nature of the plaque.展开更多
Headache is frequently encountered in clinic, including vascular headache, cervical headache, traumatic cerebral headache, and tonic headache, which may be seenin many acute or chronic diseases. During the period ... Headache is frequently encountered in clinic, including vascular headache, cervical headache, traumatic cerebral headache, and tonic headache, which may be seenin many acute or chronic diseases. During the period from Aug. 1996 - Apr. 2000, the author had treated 50 cases of headache by scalp acupuncture therapy and got quite satisfactory therapeutic results as reported in the following.
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Clinically, occipital neuralgia is commonly encountered. It is manifested by pain in the unilateral suboccipital and postmastoid region, which may radiate to the upper occipital part, the ear and copular part, and eve...Clinically, occipital neuralgia is commonly encountered. It is manifested by pain in the unilateral suboccipital and postmastoid region, which may radiate to the upper occipital part, the ear and copular part, and even to the orbit. The pain is severe, and often cause spasm of the cervical muscles. The authors applied acupuncture for treating occipital neuralgia with good therapeutic results reported as follows.展开更多
Case History
Mr. Li, a university student aged 23 years, paid his first visit on July 16, 2001, with the chief complaint of abdominal pain for one day. The patient stated that one day before when it happened to be the...Case History
Mr. Li, a university student aged 23 years, paid his first visit on July 16, 2001, with the chief complaint of abdominal pain for one day. The patient stated that one day before when it happened to be the weekend, he got abdominal pain after supper, which went worse gradually and caused him to roll all over in bed. The pain was slightly alleviated half an hour later after he had taken some pain killers. Upon inquiry, the patient said that because of their newly graduation from the university, he and his classmates were so excited that they went to have a sumptuous lunch with alcoholic drinks. And in the evening he ate again a delicious supper cooked for him by his mother, after which he continued to have some fruit and dessert.展开更多
Case HistoryPatient Lu,a male engineer aged 27 years,paid hisfirst visit on March 12,1990,with the chief complaint ofinsomnia for 3 months.The patient Stated that he hadonce got insomnia 5 years before when he was stu...Case HistoryPatient Lu,a male engineer aged 27 years,paid hisfirst visit on March 12,1990,with the chief complaint ofinsomnia for 3 months.The patient Stated that he hadonce got insomnia 5 years before when he was studyingat school,and it was cured later.In the recent 3 months,展开更多
The hulbar paralysis of upper rnotor neurons is a common seniIe disease. ln recentycars. we select Lianquan (CV 23 ) as a chief point in comhination with Jinjin (EX-HN l2 ). Yuye(FX-HN 13 ) and Zhaohai (KI 6 ) and emp...The hulbar paralysis of upper rnotor neurons is a common seniIe disease. ln recentycars. we select Lianquan (CV 23 ) as a chief point in comhination with Jinjin (EX-HN l2 ). Yuye(FX-HN 13 ) and Zhaohai (KI 6 ) and employ uniform reinforcing-reducing manipuIation to treat 280patients. The results show that a total effectivc rate is 55. 71％. The possible mechanisms are dis-cussed preliminarily in thc present paper.展开更多
文摘Objective:To explore the main acupoint prescription and mechanism of acupuncture in treating Functional dyspepsia(FD)by analyzing the clinical randomized controlled trial literature on acupoints and targets of acupuncture in the treatment of FD combined with association rule mining and bioinformatics/network pharmacology methods.Methods:Search relevant clinical randomized controlled trial literature on acupoints and therapeutic targets of acupuncture in the treatment of FD from eight databases from their inception to June 18th,2022.We obtained acupuncture selection points,meridian,and therapeutic targets and established acupoints database for acupuncture treatment of FD.FD-related targets were collected from GeneCards,DisGeNET,OMIM,and DrugBank databases.We obtained the potential targets of acupuncture on FD by taking the intersection of acupuncture for FD therapeutic targets and FD-related targets.We performed the protein-protein interaction network,Gene Ontology(GO)analysis,and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis.Results:In this study,26 Randomized Controlled Trials related to acupuncture treatment of FD were retrieved.We obtained 29 acupoints,17 acupuncture for FD therapeutic targets,and 10 intersection targets.Tumor necrosis factor(TNF),Interleukin(IL)-1,and Neuropeptide Y(NPY)are key targets of acupuncture in the treatment of FD.Conclusion:ST36-CV12-PC6-LR3 is the main acupoint prescription for FD.Acupuncture may affect Neuroactive ligand-receptor interaction,Gastric acid secretion,and IL-17,TNF signaling pathways by regulating related key targets,and play a synergistic role in the treatment of FD by inhibiting gastric acid secretion,alleviating inflammatory response,regulating the brain-gut axis,improving mood and other aspects.
文摘Inflammatory arthritis refers to the migration of inflammatory cells(such as monocytes/macrophages,lymphocytes,and granulocytes)from the blood to the synovium or synovial fluid,causing joint pain and swelling.It is often associated with decreased joint mobility and functional damage.Some diseases lead to cartilage and skeletal damage,resulting in joint destruction.Common inflammatory arthritis includes rheumatoid arthritis,ankylosing spondylitis,and gout.
基金Tianjin Administration of Traditional Chinese Medicine Research Project of Integrated Traditional Chinese and Western Medicine(No.2021147).
文摘Acne is a chronic inflammatory skin disease involving hair follicle sebaceous glands,which is characterized by acne,papules,pustules,nodules,cysts and so on.The disorder of immune inflammation is the key link.A variety of factors participate in the immune inflammatory response of acne and interact with each other,leading to the occurrence and development of acne inflammation.Acupuncture can regulate the immune and inflammatory response through many links and improve the skin lesions.This study explains potential mechanisms of acupuncture in the treatment of acne by regulating the body's immune inflammatory response,in order to provide new ideas.
文摘 This study was carried out in 120 patients affected by migraine without aura, treated in 4 public health centers and randomly divided into acupuncture group (AG) and conventional drug therapy group (CDTG).
The evaluation of clinical results was made 6 and 12 months after the beginning of treatment and was worked out as well according to socio-medical parameters. Acupuncture was applied to the following points: Touwei (ST 8), Xuanlu (GB 5), Fengchi (GB 20), Dazhui (GV 14), Lieque (LU 7), treated with the reducing method. In AG, the figure scoring the entity and frequency of migraine attacks drops from 9,823 before treatment to 1,990 6 months after and 1,590 12 months after; while in CDTG, it drops from 8,405 before treatment to 3,927 6 months after and 3,084 12 months after. In AG, the total absence from work amounted to 1,120 working days/year, with a total cost (private + social costs) of 186,677,000 Italian liras. In CDTG, the absence from work amounted to 1,404 working days/year, with a total cost of 266,614,000 Italian liras.
If we consider that in Italy the patients affected by migraine without aura are around 800,000, and that acupuncture therapy is able to save 1,332,000 Italian liras on the total average cost supported for every single patient, the application of acupuncture in the treatment of migraine without aura would allow a saving of the health expenses in Italy of over 1,000 billion liras.
文摘 Hyperplasia of mammary glands is a common disease in the middle-aged women, and it is a precancerous lesion of mammary glands. For many years, the author has used Rugen (ST 18) of the Stomach Meridian of Foot-Yangming as the main point withcertain auxiliary points chosen on basis of the differentiation types to treat the disease and obtained satisfactory therapeutic effects. A report follows.
……
文摘Yan Si Xue(咽四穴)refer to four points in the throat summarized by Prof.Sheng Canruo in his long-year clinical experience based on the combination of TCM theory and the knowledge of modernmedical anatomy.By taking “Yan Si Xue” as main points,and other differential adjunct points,Prof.Sheng has obtained satisfactory therapeutic results in treating various throat diseases such ashoarseness,paralysis of vocal cord,dysphonia after radiotherapy on throat tumor,vocal nodules,disorder of the glossopharyngeal nerve,hysteric aphasia,and acute or chronic laryngopharyngitis.
文摘Case HistoryName:Kerstin Wiest;Sex:female;Age:46 years;Occupation:teacher;Date of firstvisit:April,1996.Chief complaint:Allergic rhinitis for fiveyears.The patient stated that five years before,she got the sensation of weakness and lassitudeafter undergoing a uterectomy,which
文摘Depressive syndrome is a common complication in cerebral vascular accidents (CVA), which accounts for 70% of the complications. A mild case of the syndrome is marked by grief, sleeping disturbance, weakened mental activities, worry, loss of interest, and irritability. A severe case may have worse symptoms and signs, except the above mentioned ones, such as anxiety, reduced appetite, hallucination, delusion, desperation, etc. The author has adopted acupuncture to treat depressive syndromes after CVA with good therapeutic result as reported in the following.
文摘Dizziness and vertigo is a commonly encountered disease in clinic. There has been the saying from ancient times that "there would be no dizziness if without wind", " there would be no dizziness if without phlegm", "there would be no dizziness if without deficiency", and " there would be no dizziness if without fire". However, in the author's view, the dizziness and vertigo caused by blood stasis blocking the collaterals is most commonly seen in clinic, which should deserve more attention. The following is an introduction about the author's experience in treating 3 cases of dizziness and vertigo with acupuncture.
文摘In recent years, the author has treated 57 cases of hiccup due to radiotherapy, chemotherapy or introducing therapy by acupuncture with satisfactory results as reported in the following.
基金Clinical Study on Quantitative Evaluation of Therapeutic Effect of Acupuncture and Moxibustion Treating Carotid Arteriosclerosis by Ultra-Speed Pulse Wave Imaging(No.20201137)of Acupuncture on Carotid Plaque in Patients with Phlegm-damp Constitutio(No.20191162)。
文摘Objective:To evaluate the structural changes of atherosclerotic plaque before and after acupuncture treatment by three-dimensional ultrasound of Vascular Plaque Quantification technology.Methods:Forty subjects were recruited and randomly divided into acupuncture group and sham acupuncture group.All patients were treated twice a week for 3 months and were observed the changes of the bilateral carotid plaque volume(PV),gray scale value(GSM)and inner media thickness(IMT).Results:The acupuncture group’s PV decreased after 3 months,while the sham group’s increased slightly.The result were statistically significant(P≤0.05).After treatment,the acupuncture group’s left GSM was higher than before,while the sham group’s was slightly lower than before.The result were statistically significant(P≤0.05).Although the difference of the acupuncture group’s right GSM before and after treatment was not statistically significant,it also had a rising trend.Conclusion:Acupuncture can reduce the volume of carotid atherosclerotic plaque and stabilize the nature of the plaque.
文摘 Headache is frequently encountered in clinic, including vascular headache, cervical headache, traumatic cerebral headache, and tonic headache, which may be seenin many acute or chronic diseases. During the period from Aug. 1996 - Apr. 2000, the author had treated 50 cases of headache by scalp acupuncture therapy and got quite satisfactory therapeutic results as reported in the following.
……
文摘Clinically, occipital neuralgia is commonly encountered. It is manifested by pain in the unilateral suboccipital and postmastoid region, which may radiate to the upper occipital part, the ear and copular part, and even to the orbit. The pain is severe, and often cause spasm of the cervical muscles. The authors applied acupuncture for treating occipital neuralgia with good therapeutic results reported as follows.
文摘Case History
Mr. Li, a university student aged 23 years, paid his first visit on July 16, 2001, with the chief complaint of abdominal pain for one day. The patient stated that one day before when it happened to be the weekend, he got abdominal pain after supper, which went worse gradually and caused him to roll all over in bed. The pain was slightly alleviated half an hour later after he had taken some pain killers. Upon inquiry, the patient said that because of their newly graduation from the university, he and his classmates were so excited that they went to have a sumptuous lunch with alcoholic drinks. And in the evening he ate again a delicious supper cooked for him by his mother, after which he continued to have some fruit and dessert.
文摘Case HistoryPatient Lu,a male engineer aged 27 years,paid hisfirst visit on March 12,1990,with the chief complaint ofinsomnia for 3 months.The patient Stated that he hadonce got insomnia 5 years before when he was studyingat school,and it was cured later.In the recent 3 months,
文摘The hulbar paralysis of upper rnotor neurons is a common seniIe disease. ln recentycars. we select Lianquan (CV 23 ) as a chief point in comhination with Jinjin (EX-HN l2 ). Yuye(FX-HN 13 ) and Zhaohai (KI 6 ) and employ uniform reinforcing-reducing manipuIation to treat 280patients. The results show that a total effectivc rate is 55. 71％. The possible mechanisms are dis-cussed preliminarily in thc present paper.
