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Flexible nest site selection of the endangered Oriental Storks(Ciconia boyciana):Trade-off from adaptive strategies
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作者 Lei Cheng Lizhi Zhou +2 位作者 Chao Yu Zhenhua Wei Chunhua Li 《Avian Research》 SCIE CSCD 2023年第2期242-249,共8页
Nest site selection is a vital component of bird reproduction success,and an adaptive behavior conducted to decrease nest predation risk with avoiding external disturbances.Understanding patterns of nest site selectio... Nest site selection is a vital component of bird reproduction success,and an adaptive behavior conducted to decrease nest predation risk with avoiding external disturbances.Understanding patterns of nest site selection can provide insights into how species adapt to changes in their habitat and has important conservation implications.In this study,we used microhabitat variables and multi-scale data with a field survey of nest occurrence to determine nest site selection patterns and adaptive strategies of the breeding Oriental Storks(Ciconia boyciana)in different nest areas.Results demonstrate that the nest site microhabitat characteristics of the breeding Oriental Storks significantly differed among the three nesting areas,and nest height was higher in the middle and lower Yangtze River floodplain than in the Northeast China and Bohai Bay nest areas.The food resources and intensity of human disturbance had the greatest effects on the nest site selection of the breeding Oriental Storks.The intensity of human disturbance was positively correlated with the nest height of the breeding Oriental Storks in Bohai Bay and the middle and lower Yangtze River floodplain;however,nest height decreased with the abundance of food resources in the Northeast China nest area.Our findings indicate that the nest site selection patterns of Oriental Storks showed flexible adaptive strategies.In safer environments,nests were lower and closer to food resources,which allows parent storks to invest more in the nestlings.However,in areas where human activity was intense,nests were higher to ensure the safety of their offspring.Some measures that could be taken to improve the breeding habitat of Oriental Storks include increasing the percentage of wetland areas in nesting areas to enhance food resources availability and setting artificial nests at suitable heights in potential nesting grounds to encourage nesting.Finally,the establishment of soft barriers around the nesting areas could increase the safety of nests. 展开更多
关键词 adaptive strategies Breeding range expansion Habitat characteristics Nest site selection Oriental storks
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Climate change and Chinese farmers: Perceptions and determinants of adaptive strategies 被引量:7
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作者 ZHAI Shi-yan SONG Gen-xin +2 位作者 QIN Yao-chen YE Xin-yue Mark Leipnik 《Journal of Integrative Agriculture》 SCIE CAS CSCD 2018年第4期949-963,共15页
Farmers' perceptions, beliefs, adaptive strategies, and barriers regarding climate change are critical to promoting sustainable ecosystems and societal stability. This paper is based on an extensive survey of 1 50... Farmers' perceptions, beliefs, adaptive strategies, and barriers regarding climate change are critical to promoting sustainable ecosystems and societal stability. This paper is based on an extensive survey of 1 500 farmers and their households in Henan Province in China during 2013–2014. Henan is the largest agricultural province in China with over 51 million farmers. The survey results showed that approximately 57% of the respondents perceived the direct impact of climate change during the past 10 years, with 70.3% believing that climate change posed a risk to their livelihood. Not surprisingly, most farmers reported that they have adopted new measures to mitigate the negative impacts of climate change. The main barriers hindering farmers' adopting adaptation measures were lack of funds and timely information. A multinomial logit model revealed that land ownership, knowledge of crop variety and the causes of climate change, as well as the belief of climate change, were all positively related to the likelihood of employing adaptive strategies. Moreover, the percentage of households engaging in agriculture activity, and years of engaging in farming were both negatively correlated with famer's likelihood of adopting adaptation strategies. More importantly, farmers with high incomes were less likely to adopt adaptive strategies and more willing to engage in other business activities. In conclusion, it is important to communicate climate change related information and government policies in rural areas, promote farmer associations and other educational outreach efforts to assist Chinese farmers to deal with climate change. 展开更多
关键词 climate change CHINESE FARMERS adaptive strategies HENAN PROVINCE
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Climate Change, Adaptive Strategies and Rural Livelihoods in Semiarid Tanzania 被引量:3
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作者 Richard Y. M. Kangalawe James G. Lyimo 《Natural Resources》 2013年第3期266-278,共13页
Climate change is a global challenge to both sustainable livelihoods and economic development. In Tanzania as in most African countries, farming depends almost entirely on rainfall, a situation that makes agriculture ... Climate change is a global challenge to both sustainable livelihoods and economic development. In Tanzania as in most African countries, farming depends almost entirely on rainfall, a situation that makes agriculture and thus rural livelihoods especially in semiarid environments particularly vulnerable to climate change. This study analyses the impacts of climate change and variability on rural livelihoods with particular focus on agricultural production, food security and adaptive capacities in semiarid areas of Tanzania. The methods used in this study included focus group discussions, key informant interviews, household surveys and field observations. Results from the study indicate that communities understood climate change in terms of variability in rainfall patterns and amount, temperature patterns, wind, water availability, increased incidences of drought and decreased agricultural productivity. Communities in the study area acknowledged that while rainfall amounts have decreased over the last thirty years, temperatures have increased;an experience is also supported by meteorological data. Such changes were claimed to have reduced agricultural productivity particularly due to prolonged drought, inadequate and uneven distribution of rainfall as well as unpredictable onset and ending of rains. Stressors such as crop diseases and pests, low soil fertility and inadequate extension services were also reported to contribute to the decline in agricultural productivity and re-occurrence of food insecurity. In response, communities have developed multiple adaptation strategies, including growing of drought tolerant and early maturing crop varieties, increasing wetlands cultivation, water harvesting for small-scale irrigation and livestock keeping. However, households with limited livelihood assets are more vulnerable to the impacts of climate change and food insecurity. The study argues that diversification of adaptive strategies, such as water harvesting for small-scale irrigation, integration of livestock and crop production are crucial to ensuring sustainable livelihood in a changing climate. 展开更多
关键词 CLIMATE Change adaptive strategies FOOD INSECURITY RURAL Livelihoods SEMIARID Tanzania
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Decentralized Adaptive Strategies for Synchronization of Fractional-order Complex Networks 被引量:3
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作者 Quan Xu Shengxian Zhuang +1 位作者 Yingfeng Zeng Jian Xiao 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2017年第3期543-550,共8页
This paper focuses on synchronization of fractionalorder complex dynamical networks with decentralized adaptive coupling.Based on local information among neighboring nodes,two fractional-order decentralized adaptive s... This paper focuses on synchronization of fractionalorder complex dynamical networks with decentralized adaptive coupling.Based on local information among neighboring nodes,two fractional-order decentralized adaptive strategies are designed to tune all or only a small fraction of the coupling gains respectively.By constructing quadratic Lyapunov functions and utilizing fractional inequality techniques,Mittag-Leffler function,and Laplace transform,two sufficient conditions are derived for reaching network synchronization by using the proposed adaptive laws.Finally,two numerical examples are given to verify the theoretical results. 展开更多
关键词 Decentralized adaptive control fractional-order complex networks quadratic Lyapunov functions SYNCHRONIZATION
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Farmer's Adaptive Strategies on Land Competition between Societal Outcomes and Agroecosystem Conservation in the Purple-soiled Hilly Region,Southwestern China 被引量:2
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作者 TANG Qiang BAO Yuhai +2 位作者 HE Xiubin ZHU Bo ZHANG Xinbao 《Journal of Mountain Science》 SCIE CSCD 2012年第1期77-86,共10页
The worldwide extension and intensification of farming during the last century has led to ecosystem degradation and caused a series of environmental problems.Conservation of ecosystem services in agricultural regions ... The worldwide extension and intensification of farming during the last century has led to ecosystem degradation and caused a series of environmental problems.Conservation of ecosystem services in agricultural regions has been implemented by top-down government actions or initiated by resilience scientists in the developed countries,but little attention was paid in the developing countries,especially in some remote mountainous regions.The present paper presents a case study showing how local farmers obtained both maximal societal outcomes and agroecosystem conservation interests in the absence of distinct boundaries between agricultural and protected ecological areas in the densely populated purple-soiled hilly region of southwestern China.The local community(Yanting County) has developed a mosaic agricultural-forestry-fishery-stock breeding system with spatially targeted land uses,diverse agricultural productions and multiple ecological partnerships.It indicates that the local farmers have hereditarily perceived sound strategies on maximizing sustainable societal outcomes and optimizing tradeoffs among macro-market,state policy,new technological facility and ecological reinforcement. 展开更多
关键词 生态系统保护 中国西南地区 农业区域 土地用途 自适应策略 社会 农民 丘陵区
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Effect of Socio-Demographic Characteristics on Kenyan Smallholder Dairy Farmers’ Adaptive Strategies to Climate Change Effects
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作者 Charles Okech Odhiambo Chlirukovian Bwire Wasike Harun Okello Ogindo 《Atmospheric and Climate Sciences》 2019年第4期583-599,共17页
Climate change (CC) impedes smallholder dairy industry in Kenya. Consequently, farmers’ adaptation to CC effects would greatly determine their resilience, profitability, and sustainable contribution to the economy. S... Climate change (CC) impedes smallholder dairy industry in Kenya. Consequently, farmers’ adaptation to CC effects would greatly determine their resilience, profitability, and sustainable contribution to the economy. Socio-demography among other factors, determine smallholder farmers’ adaptive strategies to CC effects. This study sought to understand how smallholder dairy farmers in South Western Kenya adapt to climate changes and determine the relationship between famers’ adaptive strategies and their socio-demographics of sex, age, marital status, highest educational level, household size, and experience in dairying. Concurrent Fixed Mixed Methods were used to collect primary and secondary data. Reports and papers were reviewed for temperature and precipitation data, dairy population, production trends, and farmers’ socio-demographics. A survey questionnaire was administered to 367 smallholder dairy household heads with 10 years’ experience obtained through multi-stage sampling of respondents from 4 sub counties of Migori county. The data collected included the respondents’ socio-demographics, climate changes and adaptability to CC effects. Key informant interviews (KIIs) were conducted with heads of government departments of Livestock Production, Cooperative Development, Meteorology, Environment and Agriculture Sector Development Support Programme (ASDSP) in Migori County. Others included the leadership of Rongo Dairy Farmers’ Cooperative Society, Lichota Livestock Development Farm, and a Research Officer for Livestock Production Systems with Kenya Agriculture and Livestock Research Organization (KALRO). Focus group discussions (FGDs), on the other hand, were conducted with old men and women (aged 60 years and above), and farmer groups from Rongo Dairy Farmers Cooperative Society, Cham Gi Wadu Dairy and Multipurpose Cooperative Society, and East Sakwa Farmers’ Development Group. These were obtained purposively based on dairying experience. Descriptive statistics (percentages) were used to describe climate change effect on smallholder dairying and farmers’ adaptation. Percentages, minimum and maximum values, means, range, and standard deviations were used to describe respondents’ socio-demographics. Binary logistic regression analysis was used to determine the effect of farmers’ socio-demographics on their adaptive strategies to CC effects. Results indicated that individually, male farmers were more likely to adopt mixed crop and livestock farming (Odds = 3.97;p = 0.02) and experience an increasing trend in income earning from milk sales (Odds = 0.63;p = 0.04). Individually, older farmers were significantly more likely to establish own fodder (Odds = 0.96;p = 0.03), keep non-Friesians and their crosses (Odds = 0.97;p = 0.02), and experience increasing trends in income earned from milk sales (odds = 1.02;p = 0.02). Individually, household size significantly influenced establishment of own fodder (Odds = 0.69;p = 0.00) and jointly with the other 5 socio-demographic factors (Odds = 0.70;p = 0.00). With other socio-demographic factors, male farmers were more likely to rely mainly on household labour (Odds = 0.32;p = 0.05). Thus, gender, age and household size were found to have significant effects on smallholder dairy farmers’ adaptation to climate change effects in the study area. 展开更多
关键词 SMALLHOLDER DAIRY FARMERS SOUTHWESTERN Kenya Climate Change ADAPTATION SOCIO-DEMOGRAPHIC Factors adaptive strategies
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Forest Dwellers’ Perception on Climate Change and Their Adaptive Strategies to Withstand Impacts in Mizoram, North-East India
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作者 Uttam Kumar Sahoo Soibam Lanabir Singh +4 位作者 Snehasudha S. Sahoo Lal Nundanga Lal Nuntluanga Angom S. Devi John Zothansiama 《Journal of Environmental Protection》 2018年第13期1372-1392,共21页
We studied the perception of forest-dependent communities on climate change with its associated risk and their adaptation strategies in Mizoram, Northeast India. A total of 360 respondents (household heads) were rando... We studied the perception of forest-dependent communities on climate change with its associated risk and their adaptation strategies in Mizoram, Northeast India. A total of 360 respondents (household heads) were randomly selected from 24 villages across the three different agro-climatic zones prevalent. The community perceived awareness of climate change phenomena in the region with a positive correlation between age, education and occupation of the respondents. The overall perception of climate change in temperature was medium (0.49), while low for change in precipitation (0.26) and seasonal durability (0.23). The community showed over-all low score of perception on risk of climate change (0.10) where risk on livelihood and socio-economic factors was higher than risk to environment or forest. Perception on impact of climate change was high for forest abi-otic ecological factors (0.66) and flora and fauna (0.62), while medium on livelihood of forest-dependent communities (0.44). The majority (more than 75%) of the respondents agreed that human beings are involved and responsible for climate change. Adoption of adaptive strategies to cope climate change ranged from 0.07 to 0.91, amongst which zero tillage, use of traditional knowledge, forest fire prevention, soil and water conservation techniques, agroforestry practices and social forestry are popular. However, rain water harvesting and investments for crop insurance were adopted on low scores clearly implied by the educational and socio-economic status of the farmers in the majority. The study brings out the knowledge and perceptions to climate change by forest-dependent communities and their adaptive strategies to cope had been assessed. The finding results seek the attention of researchers and policy makers to integrate technological and financial interventions in supporting farmer’s effort to cope with climate change with a long term objective for improving their livelihood and climate sensitive resources at the same time. 展开更多
关键词 PERCEPTIONS Climate Change ADAPTATION FOREST Policy NORTHEAST Indi
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Climate change impact in the Western Himalaya:people's perception and adaptive strategies 被引量:1
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作者 Vikram S.Negi Rakesh K.Maikhuri +2 位作者 Dalbeer Pharswan Shinny Thakur Pitamber P.Dhyani 《Journal of Mountain Science》 SCIE CSCD 2017年第2期403-416,共14页
The Himalaya represents a vast mountain system and globally valued for its significant role in regulation of global as well as regional climate that has direct impact on biodiversity and ecosystem services crucial for... The Himalaya represents a vast mountain system and globally valued for its significant role in regulation of global as well as regional climate that has direct impact on biodiversity and ecosystem services crucial for sustenance of millions of people in Himalaya and adjoining areas. However, mountain regions worldwide are impacted by climate change and at the same time represent distinctive area for the assessment of climate related impacts. Climate change impacts in Himalayan region have its implications on food production, natural ecosystems,retreat of glacier, water supply, human and animal health and overall human well being. The livelihood and food security of the people inhabited in region largely depend on climate sensitive sectors i.e.agriculture, livestock, forestry and their interlinkages with each other, and has the potential to break down food and nutritional security as well as livelihood support systems. People's perception and understanding of climate can be an important asset when it comes to adaptation to climate change impact;however it is not taken into consideration for the development of policy design and implementation of modern mitigation and adaptation strategies by governments and other civil society organizations.The knowledge of local people and farming communities for rural landscape management and sustainable use of bioresources is gaining credence as a key strategy to cope up with the climate change.Therefore, the present study analyzes the indigenous knowledge of local people and their perceptions on climate change, and also documented adaptation approaches at local level in mountain ecosystem of western Himalaya. The study could be useful to policy makers to design appropriate adaptation strategies to cope up with the impacts of climate change. 展开更多
关键词 喜马拉雅地区 气候变化 西部地区 感知 生态系统服务 自然生态系统 山地生态系统 粮食安全
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ADAPTIVE STRATEGIES FORNC MACHINING COMPOUND FREE-FORM SURFACES
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作者 Gao Sande Zhou Yunfei +1 位作者 Zhang Xinfang Zhou Ji 《Computer Aided Drafting,Design and Manufacturing》 1994年第2期59-65,共2页
ADAPTIVESTRATEGIESFORNCMACHININGCOMPOUNDFREE-FORMSURFACESGaoSande;ZhouYunfei;ZhangXinfang;ZhouJiADAPTIVESTRA... ADAPTIVESTRATEGIESFORNCMACHININGCOMPOUNDFREE-FORMSURFACESGaoSande;ZhouYunfei;ZhangXinfang;ZhouJiADAPTIVESTRATEGIESFORNCMACHIN... 展开更多
关键词 COMPOUND surface NC MACHINING adaptive TRIANGULATION adaptive STEP length
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Eradication Treatment of Helicobacter pylori Infection: Evaluation of Therapeutic Strategies in N’Djamena
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作者 Mayanna Habkréo Ali Mahamat Moussa +5 位作者 Tahir Mahamat Saleh Djerabet Franckly Fany Haby Mairé Dehainssala Adama Ngaré Mahamat Ali Hachim 《Open Journal of Gastroenterology》 CAS 2024年第2期59-67,共9页
Background: Helicobacter pylori (Hp) infection is the most widespread bacterial infection in the world. The infection is generally acquired in childhood, but can persist into adulthood. Eradication therapy has undergo... Background: Helicobacter pylori (Hp) infection is the most widespread bacterial infection in the world. The infection is generally acquired in childhood, but can persist into adulthood. Eradication therapy has undergone several modifications. The aim of this study was to evaluate the different therapeutic strategies used in the eradication of Helicobacter pylori infection in the Centre Hospitalier Universitaire La Reference Nationale of N’Djaména. Patients and Methods: This was a prospective, descriptive analytical study spread over one year, from September 2021 to September 2022. Patients at least 15 years of age presenting with dyspeptic symptoms, seen consecutively in a hepato-gastroenterology consultation and with a positive stool test for H. pylori infection, were included in the study. Equally, 1/3 of patients were treated with dual or triple therapy. The remaining third received quadritherapy. Results: A total of 268 patients were included in the study (mean age 38.40 ± 14.66 with extremes of 16 and 80 years). Males predominated in 58% of cases. Overall therapeutic efficacy was 88.9%. According to different therapeutic strategies, efficacy was 90.75% for dual therapy with PPI (Rabeprazole) and Amoxicillin. On the other hand, efficacy was 87% and 88.88% for PPI-based triple therapy and dual antibiotic therapy, and for PPI-based quadruple therapy and triple antibiotic therapy. Conclusion: H. pylori infection is a common disease in Chad. Dual therapy with rabeprazole combined with a high dose of amoxicillin over a period of at least two weeks showed similar if not better efficacy than triple or quadruple therapy. 展开更多
关键词 Helicobacter pylori Therapeutic strategies ERADICATION DYSPEPSIA CHAD
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Solar adaptive optics systems for the New Vacuum Solar Telescope at the Fuxian Lake Solar Observatory
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作者 Lanqiang Zhang Xuejun Rao +8 位作者 Hua Bao Youming Guo Jinsheng Yang Nanfei Yan Xian Ran Dingkang Tong Xinlong Fan Zhongyi Feng Changhui Rao 《Astronomical Techniques and Instruments》 CSCD 2024年第2期95-104,共10页
Adaptive optics(AO)is essential for high-quality ground-based observations with large telescopes because it counters the impact of wavefront aberrations caused by atmospheric turbulence.The new vacuum solar telescope(... Adaptive optics(AO)is essential for high-quality ground-based observations with large telescopes because it counters the impact of wavefront aberrations caused by atmospheric turbulence.The new vacuum solar telescope(NVST)is one of the most important high-resolution solar observation instruments in the world.Three sets of solar adaptive optics systems have been developed and installed on this telescope:conventional adaptive optics,ground layer adaptive optics,and multi-conjugate adaptive optics.These have been in operation from 2018 to 2023.This paper details the development and application of solar adaptive optics on the NVST and discusses the newest instrumentation. 展开更多
关键词 Solar observation adaptive optics Multi-conjugate adaptive optics
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Quaternion-Based Adaptive Trajectory Tracking Control of a Rotor-Missile with Unknown Parameters Identification
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作者 Jie Zhao Zhongjiao Shi +1 位作者 Yuchen Wang Wei Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2024年第1期375-386,共12页
This paper investigates the adaptive trajectory tracking control problem and the unknown parameter identification problem of a class of rotor-missiles with parametric system uncertainties.First,considering the uncerta... This paper investigates the adaptive trajectory tracking control problem and the unknown parameter identification problem of a class of rotor-missiles with parametric system uncertainties.First,considering the uncertainty of structural and aerodynamic parameters,the six-degree-of-freedom(6Do F) nonlinear equations describing the position and attitude dynamics of the rotor-missile are established,respectively,in the inertial and body-fixed reference frames.Next,a hierarchical adaptive trajectory tracking controller that can guarantee closed-loop stability is proposed according to the cascade characteristics of the 6Do F dynamics.Then,a memory-augmented update rule of unknown parameters is proposed by integrating all historical data of the regression matrix.As long as the finitely excited condition is satisfied,the precise identification of unknown parameters can be achieved.Finally,the validity of the proposed trajectory tracking controller and the parameter identification method is proved through Lyapunov stability theory and numerical simulations. 展开更多
关键词 Rotor-missile adaptive control Parameter identification Quaternion control
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Accurate models and nutritional strategies for specific oxidative stress factors: Does the dose matter in swine production?
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作者 Changming Hong Yujian Huang +6 位作者 Shuting Cao Li Wang Xuefen Yang Shenglan Hu Kaiguo Gao Zongyong Jiang Hao Xiao 《Journal of Animal Science and Biotechnology》 SCIE CAS CSCD 2024年第2期519-534,共16页
Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxid... Oxidative stress has been associated with a number of physiological problems in swine,including reduced production efficiency.Recently,although there has been increased research into regulatory mechanisms and antioxidant strategies in relation to oxidative stress-induced pig production,it remains so far largely unsuccessful to develop accurate models and nutritional strategies for specific oxidative stress factors.Here,we discuss the dose and dose intensity of the causes of oxidative stress involving physiological,environmental and dietary factors,recent research models and the antioxidant strategies to provide theoretical guidance for future oxidative stress research in swine. 展开更多
关键词 Accurate models DOSE Nutritional strategies Oxidative stress SWINE
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Ground-layer Adaptive Optics for the 2.5 m Wide-field and High-resolution Solar Telescope
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作者 Ying Yang Lan-Qiang Zhang +5 位作者 Nan-Fei Yan Jin-Sheng Yang Zhen Li Teng-Fei Song Xue-Jun Rao Chang-Hui Rao 《Research in Astronomy and Astrophysics》 SCIE CAS CSCD 2024年第3期224-236,共13页
The 2.5 m wide-field and high-resolution solar telescope(WeHoST)is currently under developing for solar observations.WeHoST aims to achieve high-resolution observations over a super-wide field of view(FOV)of5′×5... The 2.5 m wide-field and high-resolution solar telescope(WeHoST)is currently under developing for solar observations.WeHoST aims to achieve high-resolution observations over a super-wide field of view(FOV)of5′×5′,and a desired resolution of 0.3″.To meet the scientific requirements of WeHoST,the ground-layer adaptive optics(GLAO)with a specially designed wave front sensing system is as the primary consideration.We introduce the GLAO configuration,particularly the wave front sensing scheme.Utilizing analytic method,we simulate the performance of both classical AO and GLAO systems,optimize the wave front sensing system,and evaluate GLAO performance in terms of PSF uniformity and correction improvement across whole FOV.The results indicate that,the classical AO will achieve diffraction-limited resolution;the suggested GLAO configuration will uniformly improve the seeing across the full 5′×5′FOV,reducing the FWHM across the axis FOV to less than0.3″(λ≥705 nm,r0≥11 cm),which is more than two times improvement.The specially designed wave front sensor schedule offers new potential for WeHoST’s GLAO,particularly the multi-FOV GLAO and the flexibility to select the detected area.These capabilities will significantly enhance the scientific output of the telescope. 展开更多
关键词 INSTRUMENTATION adaptive optics-instrumentation detectors-instrumentation high angular resolution-methods numerical-telescopes-Sun activity
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Drug resistance mechanisms in cancers:Execution of prosurvival strategies
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作者 Pavan Kumar Dhanyamraju 《The Journal of Biomedical Research》 CAS CSCD 2024年第2期95-121,共27页
One of the quintessential challenges in cancer treatment is drug resistance.Several mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be discovered.The phenomenon o... One of the quintessential challenges in cancer treatment is drug resistance.Several mechanisms of drug resistance have been described to date,and new modes of drug resistance continue to be discovered.The phenomenon of cancer drug resistance is now widespread,with approximately 90% of cancer-related deaths associated with drug resistance.Despite significant advances in the drug discovery process,the emergence of innate and acquired mechanisms of drug resistance has impeded the progress in cancer therapy.Therefore,understanding the mechanisms of drug resistance and the various pathways involved is integral to treatment modalities.In the present review,I discuss the different mechanisms of drug resistance in cancer cells,including DNA damage repair,epithelial to mesenchymal transition,inhibition of cell death,alteration of drug targets,inactivation of drugs,deregulation of cellular energetics,immune evasion,tumor-promoting inflammation,genome instability,and other contributing epigenetic factors.Furthermore,I highlight available treatment options and conclude with future directions. 展开更多
关键词 cancer drug resistance MECHANISMS MICRORNAS treatment strategies
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Practice of Infection Prevention and Control Strategies in Risk Departments during the COVID-19 Epidemic
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作者 Minfang Wang Wenyi Ye +7 位作者 Jiefeng Huang Yuexian Zhu Xuxia Yu Hao Huang Fang Xu Bo Jin Ying Yang Tieer Gan 《Advances in Infectious Diseases》 CAS 2024年第1期1-12,共12页
Objective: To explore the practice and application of infection prevention and control strategies in risk departments during the COVID-19 epidemic, and to formulate the infection prevention and control measures to pro... Objective: To explore the practice and application of infection prevention and control strategies in risk departments during the COVID-19 epidemic, and to formulate the infection prevention and control measures to provide advice and guidance in risk departments. Methods: According to the latest plan of diagnosis and treatment, prevention and control issued by the National Health Commission, expert advice and consensus, combined with the actual situation in our hospital, a series of infection prevention and control measures of COVID-19 in risk department was formulated. Results: During the epidemic period, the prevention and control measures of nine risk departments including emergency operation, anesthesiology, endoscopy center, blood purification center, otolaryngology, stomatology, medical imaging department, medical cosmetology department and pulmonary function room were established from six aspects, including pre-examination and screening, medical technology control, personnel management, personal protection, environmental disinfection, medical waste disposal, etc. Conclusion: During the epidemic period, the infection prevention and control strategy of risk departments is one of the key links to control the spread of the epidemic, and risk departments must pay attention to and strictly implement various infection prevention and control measures. 展开更多
关键词 COVID-19 Risk Department Infection Prevention and Control STRATEGY PRACTICE
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Adaptive admittance tracking control for interactive robot with prescribed performance
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作者 MENG Qingrui LIN Yan 《Journal of Systems Engineering and Electronics》 SCIE CSCD 2024年第2期444-450,共7页
An adaptive control approach is presented in this paper for tracking desired trajectories in interactive manipulators. The controller design incorporates prescribed performance functions (PPFs) to improve dynamic perf... An adaptive control approach is presented in this paper for tracking desired trajectories in interactive manipulators. The controller design incorporates prescribed performance functions (PPFs) to improve dynamic performance. Notably, the performance of the output error is confined in an envelope characterized by exponential convergence, leading to convergence to zero. This feature ensures a prompt response from admittance control and establishes a reliable safety framework for interactions. Simulation results provide practical insights,demonstrating the viability of the control scheme proposed in this paper. 展开更多
关键词 prescribed performance admittance control adaptive control ROBOTS
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Engineering Strategies for Suppressing the Shuttle Effect in Lithium–Sulfur Batteries
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作者 Jiayi Li Li Gao +7 位作者 Fengying Pan Cheng Gong Limeng Sun Hong Gao Jinqiang Zhang Yufei Zhao Guoxiu Wang Hao Liu 《Nano-Micro Letters》 SCIE EI CAS CSCD 2024年第1期187-221,共35页
Lithium–sulfur(Li–S)batteries are supposed to be one of the most potential next-generation batteries owing to their high theoretical capacity and low cost.Nevertheless,the shuttle effect of firm multi-step two-elect... Lithium–sulfur(Li–S)batteries are supposed to be one of the most potential next-generation batteries owing to their high theoretical capacity and low cost.Nevertheless,the shuttle effect of firm multi-step two-electron reaction between sulfur and lithium in liquid electrolyte makes the capacity much smaller than the theoretical value.Many methods were proposed for inhibiting the shuttle effect of polysulfide,improving corresponding redox kinetics and enhancing the integral performance of Li–S batteries.Here,we will comprehensively and systematically summarize the strategies for inhibiting the shuttle effect from all components of Li–S batteries.First,the electrochemical principles/mechanism and origin of the shuttle effect are described in detail.Moreover,the efficient strategies,including boosting the sulfur conversion rate of sulfur,confining sulfur or lithium polysulfides(LPS)within cathode host,confining LPS in the shield layer,and preventing LPS from contacting the anode,will be discussed to suppress the shuttle effect.Then,recent advances in inhibition of shuttle effect in cathode,electrolyte,separator,and anode with the aforementioned strategies have been summarized to direct the further design of efficient materials for Li–S batteries.Finally,we present prospects for inhibition of the LPS shuttle and potential development directions in Li–S batteries. 展开更多
关键词 Shuttle effect Designed strategies Li-S battery Lithium polysulfides
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Fast compressed sensing spectral measurement with adaptive gradient multiscale resolution
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作者 蓝若明 刘雪峰 +1 位作者 李天平 白成杰 《Chinese Physics B》 SCIE EI CAS CSCD 2024年第2期298-304,共7页
We propose a fast,adaptive multiscale resolution spectral measurement method based on compressed sensing.The method can apply variable measurement resolution over the entire spectral range to reduce the measurement ti... We propose a fast,adaptive multiscale resolution spectral measurement method based on compressed sensing.The method can apply variable measurement resolution over the entire spectral range to reduce the measurement time by over 75%compared to a global high-resolution measurement.Mimicking the characteristics of the human retina system,the resolution distribution follows the principle of gradually decreasing.The system allows the spectral peaks of interest to be captured dynamically or to be specified a priori by a user.The system was tested by measuring single and dual spectral peaks,and the results of spectral peaks are consistent with those of global high-resolution measurements. 展开更多
关键词 SPECTROMETER compressed sensing adaptive gradient multiscale resolution fast measurement
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The component-activity interrelationship of cobalt-based bifunctional electrocatalysts for overall water splitting:Strategies and performance
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作者 Mingjie Sun Riyue Ge +4 位作者 Sean Li Liming Dai Yiran Li Bin Liu Wenxian Li 《Journal of Energy Chemistry》 SCIE EI CAS CSCD 2024年第4期453-474,共22页
Cobalt-based electrocatalysts take advantage of potentially harmonizable microstructure and flexible coupling effects compared to commercial noble metal-based catalytic materials.However,conventional water electrolysi... Cobalt-based electrocatalysts take advantage of potentially harmonizable microstructure and flexible coupling effects compared to commercial noble metal-based catalytic materials.However,conventional water electrolysis systems based on cobalt-based monofunctional hydrogen evolution reaction(HER)or oxygen evolution reaction(OER)catalysts have certain shortcomings in terms of resource utilization and universality.In contrast,cobalt-based bifunctional catalysts(CBCs)have attracted much attention in recent years for overall water splitting systems because of their practicality and reduced preparation cost of electrolyzer.This review aims to address the latest development in CBCs for total hydrolysis.The main modification strategies of CBCs are systematically classified in water electrolysis to provide an overview of how to regulate their morphology and electronic configuration.Then,the catalytic performance of CBCs in total-hydrolysis is summarized according to the types of cobalt-based phosphides,sulfides and oxides,and the mechanism of strengthened electrocatalytic ability is emphasized through combining experiments and theoretical calculations.Future efforts are finally suggested to focus on exploring the dynamic conversion of reaction intermediates and building near-industrial CBCs,designing advanced CBC materials through micro-modulation,and addressing commercial applications. 展开更多
关键词 COBALT Bifunctional electrocatalysis Water splitting Modification strategies Electrocatalytic performances
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