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Analysis and comparison of retinal vascular parameters under different glucose metabolic status based on deep learning
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作者 Yan Jiang Di Gong +7 位作者 Xiao-Hong Chen Lin Yang Jing-Jing Xu Qi-Jie Wei Bin-Bin Chen Yong-Jiang Cai Wen-Qun Xi Zhe Zhang 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第9期1581-1591,共11页
AIM:To develop a deep learning-based model for automatic retinal vascular segmentation,analyzing and comparing parameters under diverse glucose metabolic status(normal,prediabetes,diabetes)and to assess the potential ... AIM:To develop a deep learning-based model for automatic retinal vascular segmentation,analyzing and comparing parameters under diverse glucose metabolic status(normal,prediabetes,diabetes)and to assess the potential of artificial intelligence(AI)in image segmentation and retinal vascular parameters for predicting prediabetes and diabetes.METHODS:Retinal fundus photos from 200 normal individuals,200 prediabetic patients,and 200 diabetic patients(600 eyes in total)were used.The U-Net network served as the foundational architecture for retinal arteryvein segmentation.An automatic segmentation and evaluation system for retinal vascular parameters was trained,encompassing 26 parameters.RESULTS:Significant differences were found in retinal vascular parameters across normal,prediabetes,and diabetes groups,including artery diameter(P=0.008),fractal dimension(P=0.000),vein curvature(P=0.003),C-zone artery branching vessel count(P=0.049),C-zone vein branching vessel count(P=0.041),artery branching angle(P=0.005),vein branching angle(P=0.001),artery angle asymmetry degree(P=0.003),vessel length density(P=0.000),and vessel area density(P=0.000),totaling 10 parameters.CONCLUSION:The deep learning-based model facilitates retinal vascular parameter identification and quantification,revealing significant differences.These parameters exhibit potential as biomarkers for prediabetes and diabetes. 展开更多
关键词 deep learning retinal vascular parameters segmentation model DIABETES PREDIABETES
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Analysis of the Quality of Physical and Chemical Parameters of Groundwater in Three Localities in the Sub-Prefecture of Zanzra (Ivory Coast)
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作者 Djedjess Essoh Jules-César Meledje Bi Irié Marc Gouli +3 位作者 Drissa Ouattara Kra Vanh Eric-Simon Zran Adjourma Konate Albert Trokourey 《Journal of Materials Science and Chemical Engineering》 2024年第4期1-17,共17页
The availability of groundwater of acceptable quality has become a difficult challenge to meet in many countries, particularly Côte d’Ivoire. The State of Côte d’Ivoire and rural populations are building h... The availability of groundwater of acceptable quality has become a difficult challenge to meet in many countries, particularly Côte d’Ivoire. The State of Côte d’Ivoire and rural populations are building hydraulic infrastructure for this purpose. However, the quality of water coming from these infrastructures remains to be determined. This study therefore aims to analyze certain physicochemical parameters of the groundwater of Gloazra, Kouezra and Trahonfla. These are temperature, pH, electrical conductivity, TDS, salinity level, hardness, alkalinity, chloride content and bicarbonate. To determine the pH, electrical conductivity, temperature, TDS, and salinity rate, an electrochemical analysis was carried out. The titrimetric analysis made it possible to determine the chloride and bicarbonate content, alkalinity, and hardness. The results indicate that the studied groundwater is soft and acidic with good mineralization. This water does not present a health hazard to consumers but can affect hydraulic equipment and household containers. 展开更多
关键词 Ivory Coast Gloazra Trahonfla Kouezra Physicochemical parameters Water WHO Standards
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Auto-parametric resonance of a continuous-beam-bridge model under two-point periodic excitation:an experimental investigation and stability analysis
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作者 Li Yuchun Shen Chao +1 位作者 Liu Wei Li Dong 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2024年第2期445-454,共10页
The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the ... The auto-parametric resonance of a continuous-beam bridge model subjected to a two-point periodic excitation is experimentally and numerically investigated in this study.An auto-parametric resonance experiment of the test model is conducted to observe and measure the auto-parametric resonance of a continuous beam under a two-point excitation on columns.The parametric vibration equation is established for the test model using the finite-element method.The auto-parametric resonance stability of the structure is analyzed by using Newmark's method and the energy-growth exponent method.The effects of the phase difference of the two-point excitation on the stability boundaries of auto-parametric resonance are studied for the test model.Compared with the experiment,the numerical instability predictions of auto-parametric resonance are consistent with the test phenomena,and the numerical stability boundaries of auto-parametric resonance agree with the experimental ones.For a continuous beam bridge,when the ratio of multipoint excitation frequency(applied to the columns)to natural frequency of the continuous girder is approximately equal to 2,the continuous beam may undergo a strong auto-parametric resonance.Combined with the present experiment and analysis,a hypothesis of Volgograd Bridge's serpentine vibration is discussed. 展开更多
关键词 auto-parametric resonance continuous beam bridge model two-point excitation experimental investigation stability analysis vibration of Volgograd Bridge
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Sensitivity Analysis of Multi-phase Seepage Parameters Affecting the Clayey Silt Hydrate Reservoir Productivity in the Shenhu Area,South China Sea 被引量:2
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作者 LI Yaobin XU Tianfu +3 位作者 XIN Xin ZANG Yingqi ZHU Huixing YUAN Yilong 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2023年第6期1787-1800,共14页
Natural gas hydrate(NGH)is an important future resource for the 21st century and a strategic resource with potential for commercial development in the third energy transition.It is of great significance to accurately ... Natural gas hydrate(NGH)is an important future resource for the 21st century and a strategic resource with potential for commercial development in the third energy transition.It is of great significance to accurately predict the productivity of hydrate-bearing sediments(HBS).The multi-phase seepage parameters of HBS include permeability,porosity,which is closely related to permeability,and hydrate saturation,which has a direct impact on hydrate content.Existing research has shown that these multi-phase seepage parameters have a great impact on HBS productivity.Permeability directly affects the transmission of pressure-drop and discharge of methane gas,porosity and initial hydrate saturation affect the amount of hydrate decomposition and transmission process of pressure-drop,and also indirectly affect temperature variation of the reservoir.Considering the spatial heterogeneity of multi-phase seepage parameters,a depressurization production model with layered heterogeneity is established based on the clayey silt hydrate reservoir at W11 station in the Shenhu Sea area of the South China Sea.Tough+Hydrate software was used to calculate the production model;the process of gas production and seepage parameter evolution under different multi-phase seepage conditions were obtained.A sensitivity analysis of the parameters affecting the reservoir productivity was conducted so that:(a)a HBS model with layered heterogeneity can better describe the transmission process of pressure and thermal compensation mechanism of hydrate reservoir;(b)considering the multi-phase seepage parameter heterogeneity,the influence degrees of the parameters on HBS productivity were permeability,porosity and initial hydrate saturation,in order from large to small,and the influence of permeability was significantly greater than that of other parameters;(c)the production potential of the clayey silt reservoir should not only be determined by hydrate content or seepage capacity,but also by the comprehensive effect of the two;and(d)time scales need to be considered when studying the effects of changes in multi-phase seepage parameters on HBS productivity. 展开更多
关键词 energy resources natural gas hydrate sensitivity analysis seepage parameters clayey silt reservoir Pearl River Mouth Basin
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Parameter sensitivity analysis for a biochemically-based photosynthesis model
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作者 Tuo Han Qi Feng TengFei Yu 《Research in Cold and Arid Regions》 CSCD 2023年第2期73-84,共12页
A challenge for the development of Land Surface Models(LSMs) is improving transpiration of water exchange and photosynthesis of carbon exchange between terrestrial plants and the atmosphere, both of which are governed... A challenge for the development of Land Surface Models(LSMs) is improving transpiration of water exchange and photosynthesis of carbon exchange between terrestrial plants and the atmosphere, both of which are governed by stoma in leaves. In the photosynthesis module of these LSMs, variations of parameters arising from diversity in plant functional types(PFTs) and climate remain unclear. Identifying sensitive parameters among all photosynthetic parameters before parameter estimation can not only reduce operation cost, but also improve the usability of photosynthesis models worldwide. Here, we analyzed 13 parameters of a biochemically-based photosynthesis model(FvCB), implemented in many LSMs, using two sensitivity analysis(SA) methods(i.e., the Sobol’ method and the Morris method) for setting up the parameter ensemble. Three different model performance metrics, i.e.,Root Mean Squared Error(RMSE), Nash Sutcliffe efficiency(NSE), and Standard Deviation(STDEV) were introduced for model assessment and sensitive parameters identification. The results showed that among all photosynthetic parameters only a small portion of parameters were sensitive, and the sensitive parameters were different across plant functional types: maximum rate of Rubisco activity(Vcmax25), maximum electron transport rate(Jmax25), triose phosphate use rate(TPU) and dark respiration in light(Rd) were sensitive in broad leafevergreen trees(BET), broad leaf-deciduous trees(BDT) and needle leaf-evergreen trees(NET), while only Vcmax25and TPU are sensitive in short vegetation(SV), dwarf trees and shrubs(DTS), and agriculture and grassland(AG). The two sensitivity analysis methods suggested a strong SA coherence;in contrast, different model performance metrics led to different SA results. This misfit suggests that more accurate values of sensitive parameters, specifically, species specific and seasonal variable parameters, are required to improve the performance of the FvCB model. 展开更多
关键词 Sobol’method Morris method PHOTOSYNTHESIS parameters sensitivity analysis FvCB model
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Analysis of Additional Damping Control Strategy and Parameter Optimization for Improving Small Signal Stability of VSC-HVDC System
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作者 Hui Fang Jingsen Zhou +3 位作者 Hanjie Liu Yanxu Wang Hongji Xiang Yechun Xin 《Energy Engineering》 EI 2023年第4期931-948,共18页
The voltage source converter based high voltage direct current(VSC-HVDC)system is based on voltage source converter,and its control system is more complex.Also affected by the fast control of power electronics,oscilla... The voltage source converter based high voltage direct current(VSC-HVDC)system is based on voltage source converter,and its control system is more complex.Also affected by the fast control of power electronics,oscillation phenomenon in wide frequency domain may occur.To address the problem of small signal stability of the VSCHVDC system,a converter control strategy is designed to improve its small signal stability,and the risk of system oscillation is reduced by attaching a damping controller and optimizing the control parameters.Based on the modeling of the VSC-HVDC system,the general architecture of the inner and outer loop control of the VSCHVDC converter is established;and the damping controllers for DC control and AC control are designed in the phase-locked loop and the inner and outer loop control parts respectively;the state-space statemodel of the control system is established to analyze its performance.And the electromagnetic transient simulation model is built on the PSCAD/EMTDC simulation platform to verify the accuracy of the small signal model.The influence of the parameters of each control part on the stability of the system is summarized.The main control parts affecting stability are optimized for the phenomenon of oscillation due to changes in operation mode occurring on the AC side due to faults and other reasons,which effectively eliminates system oscillation and improves system small signal stability,providing a certain reference for engineering design. 展开更多
关键词 VSC-HVDC system small signal modeling eigenvalue analysis parameter optimization
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Parameterization Transfer for a Planar Computational Domain in Isogeometric Analysis 被引量:1
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作者 Jinlan Xu Shuxin Xiao +1 位作者 Gang Xu Renshu Gu 《Computer Modeling in Engineering & Sciences》 SCIE EI 2023年第11期1957-1973,共17页
In this paper,we propose a parameterization transfer algorithm for planar domains bounded by B-spline curves,where the shapes of the planar domains are similar.The domain geometries are considered to be similar if the... In this paper,we propose a parameterization transfer algorithm for planar domains bounded by B-spline curves,where the shapes of the planar domains are similar.The domain geometries are considered to be similar if their simplified skeletons have the same structures.One domain we call source domain,and it is parameterized using multi-patch B-spline surfaces.The resulting parameterization is C1 continuous in the regular region and G1 continuous around singular points regardless of whether the parameterization of the source domain is C1/G1 continuous or not.In this algorithm,boundary control points of the source domain are extracted from its parameterization as sequential points,and we establish a correspondence between sequential boundary control points of the source domain and the target boundary through discrete sampling and fitting.Transfer of the parametrization satisfies C1/G1 continuity under discrete harmonic mapping with continuous constraints.The new algorithm has a lower calculation cost than a decomposition-based parameterization with a high-quality parameterization result.We demonstrate that the result of the parameterization transfer in this paper can be applied in isogeometric analysis.Moreover,because of the consistency of the parameterization for the two models,this method can be applied in many other geometry processing algorithms,such as morphing and deformation. 展开更多
关键词 Isogeometric analysis parameterization transfer discrete harmonic mapping C1/G1 continuity
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Quantifying the Euphrates Electric Conductivity Depending on Parameters by Dimensional Analysis Method
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作者 Ali Hassan Hommadi Nadhir Al-Ansari 《Engineering(科研)》 CAS 2023年第5期301-317,共17页
The searching about methods to connect the variables with each other to reach equations including multi variables. The dimensional analysis is a method to facilitate the solution of difficult mathematic equations and ... The searching about methods to connect the variables with each other to reach equations including multi variables. The dimensional analysis is a method to facilitate the solution of difficult mathematic equations and experimental formulas;therefore methods of simplifying the difficult equations and obtaining a new equation with different variables is needed. In this study will use 2 methods (statically with dimensionally analysis) to obtain electric conductivity of water of Euphrates river by multi parameters that are time (t), temperature (Te), density, viscosity, discharge and water depth in upstream of Alhindya barrage which located in Babylon governorate, Iraq during winter 2019. The equations were obtained for EC with Te and t by data were collected from Alhindya barrage office with R<sup>2</sup> = 0.999 and R<sup>2</sup> = 0.995 by statically ways. Dimension analysis was utilized via 2 stages. In first stage was obtained on equation of EC with respect to Te, water density (ρ) and dynamic viscosity (μ) with constant time, depth of water and discharge and we obtain on R<sup>2</sup> was 0.994 and R<sup>2</sup> = 0.986. In second stage was obtained formula of EC with respect to Te, water density (ρ), dynamic viscosity (μ), with variable time, depth of water and discharge with we obtain on R<sup>2</sup> = 0.945 and R<sup>2</sup> = 0.94. The result of research indicates that applying the dimension analysis to connect more than one variable with each other to find best solutions and best methods to facilitate the solving the equations. From dimension analysis gave a clear visualization of the association of several variables to give a result that helps measure the electrical conductivity of water in the absence of a water test device. 展开更多
关键词 Electric Conductivity TEMPERATURE Dimension analysis Statistical analysis
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Pulsed gas–liquid discharge plasma catalytic degradation of bisphenol A over graphene/Cd S:process parameters optimization and O_(3)activation mechanism analysis
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作者 姜楠 李学川 +4 位作者 李举 李杰 廖兵 彭邦发 刘国 《Plasma Science and Technology》 SCIE EI CAS CSCD 2023年第10期81-90,共10页
In the present work,pulsed gas–liquid hybrid discharge plasma coupled with graphene/Cd S catalyst was evaluated to eliminate bisphenol A(BPA)in wastewater.The optimization of a series of process parameters was perfor... In the present work,pulsed gas–liquid hybrid discharge plasma coupled with graphene/Cd S catalyst was evaluated to eliminate bisphenol A(BPA)in wastewater.The optimization of a series of process parameters was performed in terms of BPA degradation performance.The experimental results demonstrated that nearly 90%of BPA(20 mg l^(-1))in the synthetic wastewater(p H=7.5,σ=10μS m^(-1))was degraded by the plasma catalytic system over 0.2 g l^(-1)graphene/Cd S at 19k V with a 4 l min^(-1)air flow rate and 10 mm electrode gap within 60 min.The BPA removal rate increased with increasing the discharge voltage and decreasing the initial BPA concentration or solution conductivity.Nevertheless,either too high or too low an air flow rate,electrode gap,catalyst dosage or initial solution p H would lead to a decrease in BPA degradation.Moreover,optical emission spectroscopy was used to gain information on short-lived reactive species formed from the pulsed gas–liquid hybrid discharge plasma system.The results indicated the existence of several highly oxidative free radicals such as·O and·OH.Finally,the activation pathway of O_(3)on the catalyst surface was analyzed by density functional theory. 展开更多
关键词 pulsed discharge gas-liquid discharge wastewater treatment parameters optimization DFT calculation
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Analysis of echo signal modulation characteristic parameters on aerial and space targets
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作者 Si Chen Hai-yang Zhang +3 位作者 Chang-ming Zhao Yu Fan Hong Chen Lin Wang 《Defence Technology(防务技术)》 SCIE EI CAS CSCD 2023年第10期146-154,共9页
Based on the scattering characteristic,the comparison of RCS(radar cross-section)at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the entity.... Based on the scattering characteristic,the comparison of RCS(radar cross-section)at different positions of a target in the same direction of incidence can be obtained first by extruding or deleting part of the entity.A simulation method of aerial&space targets echo characteristics(A&STEC)is proposed that is universal to aerial and space targets.We utilize a fixed-wing UAV(unmanned aerial vehicle)and typical missiles in simulation.The echo signal modulation characteristic parameters are calculated theoretically by the atmospheric attenuation model,the finite element method and a MUMPS solver.The verification simulations show that this method can analyze the influence of the target shape,incident direction,detection position and detection frequency on echo waveform,intensity and energy distribution.The results show that the profile of echo waveform can invert the general shape of the target.The relationship between time and intensity can determine whether the target is moving towards or away from the detector in addition.These conclusions can provide a reference for the ballistic missile target tracking and the defense against UVA intrusion in theory. 展开更多
关键词 Echo signal modulation characteristic parameters Simple targets The fixed-wing UVA Missiles Scattering characteristics
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Influence analysis of complex crack geometric parameters on mechanical properties of soft rock
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作者 Yang Zhao Xin He +3 位作者 Lishuai Jiang Zongke Wang Jianguo Ning Atsushi Sainoki 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第4期290-304,共15页
Soft rocks, such as coal, are afected by sedimentary efects, and the surrounding rock mass of underground coal mines is generally soft and rich in joints and cracks. A clear and deep understanding of the relationship ... Soft rocks, such as coal, are afected by sedimentary efects, and the surrounding rock mass of underground coal mines is generally soft and rich in joints and cracks. A clear and deep understanding of the relationship between crack geometric parameters and rock mechanics properties in cracked rock is greatly important to the design of engineering rock mass struc‑tures. In this study, computed tomography (CT) scanning was used to extract the internal crack network of coal specimens. Based on the crack size and dominant crack number, the parameters of crack area, volume, length, width, and angle were statistically analyzed by diferent sampling thresholds. In addition, the Pearson correlation coefcients between the crack parameters and uniaxial compression rock mechanics properties (uniaxial compressive strength UCS, elasticity modulus E) were calculated to quantitatively analyze the impact of each parameter. Furthermore, a method based on Pearson coefcients was used to grade the correlation between crack geometric parameters and rock mechanical properties to determine threshold values. The results indicated that the UCS and E of the specimens changed with the varied internal crack structures of the specimens, the crack parameters of area, volume, length and width all showed negative correlations with UCS and E, and the dominant crack played an important role both in weakening strength and stifness. The crack parameters of the angle are all positively correlated with the UCS and E. More crack statistics can signifcantly improve the correlation between the parameters of the crack angle and the rock mechanics properties, and the statistics of the geometric parameters of at least 16 cracks or the area larger than 5 mm2 are suggested for the analysis of complex cracked rock masses or physical reproduction using 3D printing. The results are validated and further analyzed with triaxial tests. The fndings of this study have important reference value for future research regarding the accurate and efcient selection of a few cracks with a signifcant infuence on the rock mechanical properties of surrounding rock mass structures in coal engineering. 展开更多
关键词 CT scanning Complex crack Sampling threshold Soft rock Rock mechanics Crack geometric parameters
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Hot-deformation kinetics analysis and extrusion parameter optimization of a dilute rare-earth free magnesium alloy
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作者 Qinghang Wang Haowei Zhai +5 位作者 Zhaoyang Jin Junjie He Qin Yang Wenjun Liu Yulong Li Daolun Chen 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2023年第9期3302-3322,共21页
The fundamental research on thermo-mechanical conditions provides an experimental basis for high-performance Mg-Al-Ca-Mn alloys.However, there is a lack of systematical investigation for this series alloys on the hot-... The fundamental research on thermo-mechanical conditions provides an experimental basis for high-performance Mg-Al-Ca-Mn alloys.However, there is a lack of systematical investigation for this series alloys on the hot-deformation kinetics and extrusion parameter optimization. Here, the flow behavior, constitutive model, dynamic recrystallization(DRX) kinetic model and processing map of a dilute rare-earth free Mg-1.3Al-0.4Ca-0.4Mn(AXM100, wt.%) alloy were studied under different hot-compressive conditions. In addition, the extrusion parameter optimization of this alloy was performed based on the hot-processing map. The results showed that the conventional Arrhenius-type strain-related constitutive model only worked well for the flow curves at high temperatures and low strain rates. In comparison, using the machine learning assisted model(support vector regression, SVR) could effectively improve the accuracy between the predicted and experimental values. The DRX kinetic model was established, and a typical necklace-shaped structure preferentially occurred at the original grain boundaries and the second phases. The DRX nucleation weakened the texture intensity, and the further growth caused the more scattered basal texture. The hot-processing maps at different strains were also measured and the optimal hot-processing range could be confirmed at the deformation temperatures of 600~723 K and the strain rates of 0.018~0.563 s^(-1). Based on the optimum hot-processing range, a suitable extrusion parameter was considered as 603 K and 0.1 mm/s and the as-extruded alloy in this parameter exhibited a good strength-ductility synergy(yield strength of ~ 232.1 MPa, ultimate strength of ~ 278.2 MPa and elongation-to-failure of ~ 20.1%). Finally, the strengthening-plasticizing mechanisms and the relationships between the DRXed grain size, yield strength and extrusion parameters were analyzed. 展开更多
关键词 Mg-Al-Ca-Mn alloy Constitutive model Dynamic recrystallization kinetic model Extrusion parameter optimization Strengthening-plasticizing mechanisms
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Uncertainty analysis for the calculation of marine environmental design parameters in the South China Sea
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作者 Guilin LIU Xinsheng ZHOU +3 位作者 Yi KOU Fang WU Daniel ZHAO Yu XU 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2023年第2期427-443,共17页
The calculation results of marine environmental design parameters obtained from different data sampling methods,model distributions,and parameter estimation methods often vary greatly.To better analyze the uncertainti... The calculation results of marine environmental design parameters obtained from different data sampling methods,model distributions,and parameter estimation methods often vary greatly.To better analyze the uncertainties in the calculation of marine environmental design parameters,a general model uncertainty assessment method is necessary.We proposed a new multivariate model uncertainty assessment method for the calculation of marine environmental design parameters.The method divides the overall model uncertainty into two categories:aleatory uncertainty and epistemic uncertainty.The aleatory uncertainty of the model is obtained by analyzing the influence of the number and the dispersion degree of samples on the information entropy of the model.The epistemic uncertainty of the model is calculated using the information entropy of the model itself and the prediction error.The advantages of this method are that it does not require many-year-observation data for the marine environmental elements,and the method can be used to analyze any specific factors that cause model uncertainty.Results show that by applying the method to the South China Sea,the aleatory uncertainty of the model increases with the number of samples and then stabilizes.A positive correlation was revealed between the dispersion of the samples and the aleatory uncertainty of the model.Both the distribution of the model and the parameter estimation results of the model have significant effects on the epistemic uncertainty of the model.When the goodness-of-fit of the model is relatively close,the best model can be selected according to the criterion of the lowest overall uncertainty of the models,which can both ensure a better model fit and avoid too much uncertainty in the model calculation results.The presented multivariate model uncertainty assessment method provides a criterion to measure the advantages and disadvantages of the marine environmental design parameter calculation model from the aspect of uncertainty,which is of great significance to analyze the uncertainties in the calculation of marine environmental design parameters and improve the accuracy of the calculation results. 展开更多
关键词 South China Sea marine environmental design parameters model uncertainty information entropy Monte Carlo method
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Assessment of hindlimb motor recovery affer severe thoracic spinal cord injury in rats: classification of CatWalk XT■ gait analysis parameters 被引量:1
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作者 Guoli Zheng Hao Zhang +6 位作者 Mohamed Tail Hao Wang Johannes Walter Thomas Skutella Andreas Unterberg Klaus Zweckberger Alexander Younsi 《Neural Regeneration Research》 SCIE CAS CSCD 2023年第5期1084-1089,共6页
Assessment of locomotion recovery in preclinical studies of experimental spinal cord injury remains challenging. We studied the CatWalk XT■gait analysis for evaluating hindlimb functional recovery in a widely used an... Assessment of locomotion recovery in preclinical studies of experimental spinal cord injury remains challenging. We studied the CatWalk XT■gait analysis for evaluating hindlimb functional recovery in a widely used and clinically relevant thoracic contusion/compression spinal cord injury model in rats. Rats were randomly assigned to either a T9 spinal cord injury or sham laminectomy. Locomotion recovery was assessed using the Basso, Beattie, and Bresnahan open field rating scale and the CatWalk XT■gait analysis. To determine the potential bias from weight changes, corrected hindlimb(H) values(divided by the unaffected forelimb(F) values) were calculated. Six weeks after injury, cyst formation, astrogliosis, and the deposition of chondroitin sulfate glycosaminoglycans were assessed by immunohistochemistry staining. Compared with the baseline, a significant spontaneous recovery could be observed in the CatWalk XT■parameters max intensity, mean intensity, max intensity at%, and max contact mean intensity from 4 weeks after injury onwards. Of note, corrected values(H/F) of CatWalk XT■parameters showed a significantly less vulnerability to the weight changes than absolute values, specifically in static parameters. The corrected CatWalk XT■parameters were positively correlated with the Basso, Beattie, and Bresnahan rating scale scores, cyst formation, the immunointensity of astrogliosis and chondroitin sulfate glycosaminoglycan deposition. The CatWalk XT■gait analysis and especially its static parameters, therefore, seem to be highly useful in assessing spontaneous recovery of hindlimb function after severe thoracic spinal cord injury. Because many CatWalk XT■parameters of the hindlimbs seem to be affected by body weight changes, using their corrected values might be a valuable option to improve this dependency. 展开更多
关键词 Basso Beattie and Bresnahan rating scale behavioral assessment CatWalk XT■gait analysis contusive and compressive injury hindlimb motor function histological changes spinal cord injury spontaneous recovery THORACIC weight
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Statistical analysis on the influence of mechanical parameters in the vibration of pylons
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作者 Georgios I.Dadoulis George D.Manolis 《Earthquake Engineering and Engineering Vibration》 SCIE EI CSCD 2023年第1期263-278,共16页
We present a statistical investigation of the degree of influence that assumptions made in relation to the mechanical parameters of a pylon have on its ground-induced vibrations.The study is set up by using as a key k... We present a statistical investigation of the degree of influence that assumptions made in relation to the mechanical parameters of a pylon have on its ground-induced vibrations.The study is set up by using as a key kinematic variable the displacement at the top of a reference,a stand-alone pylon with a uniform cross-section and fixity at its base.Next,statistics are produced using a dimensionless displacement ratio defined between the‘parental’and the‘subsidiary’cases,the latter defined for the pylon(a)resting on compliant soil,(b)having an attached top mass,and(c)being non-uniform with height.Furthermore,two materials are examined,namely,steel and reinforced concrete(R/C).More specifically,this displacement ratio is independent of the excitation and plays the role of a transfer function between the base and the top of the pylon.Both horizontal and vertical motions are considered,and the equations of motion are solved in the frequency domain.The ensuing statistical analysis is conducted for the following parameter combinations:(a)pylon founded on soft,intermediate,and stiff soil;(b)low,intermediate,and high-mass ratios of the attached mass to the pylon′s mass;(c)a constant and quadratic degree of pylon tapering with height.Spearman correlation coefficients are calculated for all the above combinations to arrive at statistical results that establish validity bounds and quantify the degree of influence of each assumption on the pylon′s response. 展开更多
关键词 pylons statistical analysis spearman coefficients structural vibrations elastic waveguides attached masses soil springs TAPERING
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Analysis of Morphometric Parameters and Radioactive Characteristics Using Remote Sensing Data and GIS Techniques in the Wadi Wizr Basin Area, Central Eastern Desert, Egypt
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作者 Sameh Anwar Ibrahim Hammouda Soliman Abu Elatta A. Mahmoud 《Journal of Geoscience and Environment Protection》 2023年第6期197-219,共23页
The purpose of this study is to demonstrate how modern technologies such as geographic information systems (GIS) and digital elevation models can help in the creation of a geographic database for the Wadi Wizr basin i... The purpose of this study is to demonstrate how modern technologies such as geographic information systems (GIS) and digital elevation models can help in the creation of a geographic database for the Wadi Wizr basin in Egypt’s Central Eastern Desert, in addition to examining and analysing the radioactive properties of various rocks. This was accomplished with the help of a digital elevation model (DEM) with a 30 metre accuracy and GIS software in 10.8 Arc Map. The RS-230 was also used to measure uranium and thorium concentrations. GIS softwares and digital elevation models have been shown to be more effective than the traditional method. This was demonstrated by the flexible and quick working method, the accuracy of the parameters used, and the results of the morphometric analysis of the basin river network. In addition to, the main drainage pattern from subtype to tree type, where the branching ratio was (1.59). This basin could also cause flooding. Similar studies, according to the results of this study, should make greater use of geographic information system technology and modern data sources. Wadi Wizr also has a radioactive anomaly, with uranium equivalent concentrations reaching 70 ppm in some fault parts. 展开更多
关键词 Wadi Wizr Basin Morphometric analysis Drainage Pattern Radioactive Characteristics Remote Sensing Geographic Information System
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Finite Element Analysis of the Influence of Artificial Cementation on the Strength Parameters and Bearing Capacity of Sandy Soil under a Strip Footing
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作者 Mohammad T. Alkhamis Abdulla AL-Rashidi 《Open Journal of Civil Engineering》 2023年第2期221-236,共16页
Artificial cementation is a method commonly used to enhance and improve soil properties. This paper investigates the effect of using different amounts of cement on soil strength parameters and soil bearing capacity, u... Artificial cementation is a method commonly used to enhance and improve soil properties. This paper investigates the effect of using different amounts of cement on soil strength parameters and soil bearing capacity, using the finite element method. Experimental tests are conducted on soil samples with different amounts of Portland cement. A 2-D numerical model is created and validated using the numerical modelling software, COMSOL Multiphysics 5.6 software. The study finds that the cohesion, and the angle of the internal friction of the soil samples increase significantly as a result of adding 1%, 2%, and 4% of Portland cement. The results demonstrate that the stresses and strain under the strip footing proposed decrease by 3.24% and 7.42%. Moreover, the maximum displacement also decreases by 1.47% and 2.97%, as a result of adding cements of 2% and 4%. The bearing capacity values obtained are therefore excellent, especially when using the 2% and 4% cement. The increase identified is due to the increased values of the bearing capacity factors. It is concluded that from an economic viewpoint, using 2% cement is the best option. 展开更多
关键词 Artificial Cementation Strength parameters Bearing Capacity Finite Element Method Strip Footing
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Analysis of Serum Cys-C,TBA,and Routine Blood Parameters of Patients with Hepatitis B-Related Decompensated Cirrhosis
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作者 Yu Li Yifei Lv +1 位作者 Feng-Yu Xi Ying Gao 《Journal of Clinical and Nursing Research》 2023年第3期28-32,共5页
Objective:To study the levels of serum cystatin C(Cys-C),total bile acid(TBA),and other routine blood parameters on patients with decompensated hepatitis B cirrhosis.Methods:Study group 1 consisted of 30 patients with... Objective:To study the levels of serum cystatin C(Cys-C),total bile acid(TBA),and other routine blood parameters on patients with decompensated hepatitis B cirrhosis.Methods:Study group 1 consisted of 30 patients with hepatitis B-related decompensated cirrhosis,and study group 2 consisted of 30 patients with hepatitis B;while the control group consisted of 30 healthy people who underwent physical examination.The blood parameters were used to evaluate the clinical treatment effect of patients.Results:The TBA,Cys-C,alanine transaminase(ALT),total bilirubin(TBIL),aspartate aminotransferase(AST),and international normalized ratio(INR)in study group 1 were significantly higher than those of study group 2 and the control group;while the platelet count(PLT),hemoglobin(Hb),albumin(ALB),and estimated glomerular filtration rate(eGFR)were significantly lower in the study group 1 compared to the control group and study group 2(P<0.05).The Cys-C,PLT,TBA,AST,TBIL,and INR of patients in study group 1 who were successfully treated were significantly lower than the patients who were not successfully treated(P<0.05).Conclusion:Serum Cys-C,TBA,and routine blood parameters are useful in predicting the condition and the prognosis of patients of hepatitis B-related decompensated cirrhosis. 展开更多
关键词 Serum Cys-C TBA Routine blood parameters Hepatitis B-related decompensated cirrhosis
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Rigorous back analysis of shear strength parameters of landslide slip 被引量:6
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作者 张科 曹平 保瑞 《Transactions of Nonferrous Metals Society of China》 SCIE EI CAS CSCD 2013年第5期1459-1464,共6页
A rigorous back analysis of shear strength parameters of landslide slip was presented. Kinematical element method was adopted to determine factor of safety and critical failure surface, which overcomes the disadvantag... A rigorous back analysis of shear strength parameters of landslide slip was presented. Kinematical element method was adopted to determine factor of safety and critical failure surface, which overcomes the disadvantage of limit equilibrium method. The theoretical relationship between the combination of shear strength parameters and stability state was studied. The results show that the location of critical slip surface, F/tan f and F/c depend only on the value of c/tan f. The failure surface moves towards the inside of slope as c/tan f increases. According to the information involving factor of safety and critical failure surface in a specific cross-section, strength parameters can be back calculated based on the above findings. Three examples were given for demonstrating the validity of the present method. The shear strength parameters obtained by back analysis are almost consistent with their correct solutions or test results. 展开更多
关键词 slope stability back analysis kinematical element method shear strength parameter critical failure surface
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Value of Texture Analysis of Intravoxel Incoherent Motion Parameters in Differential Diagnosis of Pancreatic Neuroendocrine Tumor and Pancreatic Adenocarcinoma 被引量:8
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作者 王英伟 张兴华 +5 位作者 王波涛 王叶 刘梦琦 王海屹 叶慧义 陈志晔 《Chinese Medical Sciences Journal》 CAS CSCD 2019年第1期1-9,共9页
Objective To evaluate the value of texture features derived from intravoxel incoherent motion(IVIM) parameters for differentiating pancreatic neuroendocrine tumor(pNET) from pancreatic adenocarcinoma(PAC).Methods Eigh... Objective To evaluate the value of texture features derived from intravoxel incoherent motion(IVIM) parameters for differentiating pancreatic neuroendocrine tumor(pNET) from pancreatic adenocarcinoma(PAC).Methods Eighteen patients with pNET and 32 patients with PAC were retrospectively enrolled in this study. All patients underwent diffusion-weighted imaging with 10 b values used(from 0 to 800 s/mm2). Based on IVIM model, perfusion-related parameters including perfusion fraction(f), fast component of diffusion(Dfast) and true diffusion parameter slow component of diffusion(Dslow) were calculated on a voxel-by-voxel basis and reorganized into gray-encoded parametric maps. The mean value of each IVIM parameter and texture features [Angular Second Moment(ASM), Inverse Difference Moment(IDM), Correlation, Contrast and Entropy] values of IVIM parameters were measured. Independent sample t-test or Mann-Whitney U test were performed for the betweengroup comparison of quantitative data. Regression model was established by using binary logistic regression analysis, and receiver operating characteristic(ROC) curve was plotted to evaluate the diagnostic efficiency.Results The mean f value of the pNET group were significantly higher than that of the PAC group(27.0% vs. 19.0%, P = 0.001), while the mean values of Dfast and Dslow showed no significant differences between the two groups. All texture features(ASM, IDM, Correlation, Contrast and Entropy) of each IVIM parameter showed significant differences between the pNET and PAC groups(P = 0.000-0.043). Binary logistic regression analysis showed that texture ASM of Dfast and texture Correlation of Dslow were considered as the specific imaging variables for the differential diagnosis of pNET and PAC. ROC analysis revealed that multiple texture features presented better diagnostic performance than IVIM parameters(AUC 0.849-0.899 vs. 0.526-0.776), and texture ASM of Dfast combined with Correlation of Dslow in the model of logistic regression had largest area under ROC curve for distinguishing pNET from PAC(AUC 0.934, cutoff 0.378, sensitivity 0.889, specificity 0.854). Conclusion Texture analysis of IVIM parameters could be an effective and noninvasive tool to differentiate pNET from PAC. 展开更多
关键词 NEUROENDOCRINE TUMOR PANCREATIC ADENOCARCINOMA texture analysis intravoxel INCOHERENT motion differential diagnosis
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