A critical function of flow cytometry is to count the concentration of blood cells,which helps in the diagnosis of certain diseases.However,the bulky nature of commercial flow cytometers makes such tests only availabl...A critical function of flow cytometry is to count the concentration of blood cells,which helps in the diagnosis of certain diseases.However,the bulky nature of commercial flow cytometers makes such tests only available in hospitals or laboratories,hindering the spread of point-of-care testing(POCT),especially in underdeveloped areas.Here,we propose a smart Palm-size Optofluidic Hematology Analyzer based on a miniature fluorescence microscope and a microfluidic platform to lighten the device to improve its portability.This gadget has a dimension of 35×30×80 mm and a mass of 39 g,less than 5%of the weight of commercially available flow cytometers.Additionally,automatic leukocyte concentration detection has been realized through the integration of image processing and leukocyte counting algorithms.We compared the leukocyte concentration measurement between our approach and a hemocytometer using the Passing-Bablok analysis and achieved a correlation coefficient of 0.979.Through Bland-Altman analysis,we obtained the relationship between their differences and mean measurement values and established 95%limits of agreement,ranging from−0.93×10^(3)to 0.94×10^(3)cells/μL.We anticipate that this device can be used widely for monitoring and treating diseases such as HIV and tumors beyond hospitals.展开更多
A network analyzer can often comprehend many protocols, which enables it to display talks taking place between hosts over a network. A network analyzer analyzes the device or network response and measures for the oper...A network analyzer can often comprehend many protocols, which enables it to display talks taking place between hosts over a network. A network analyzer analyzes the device or network response and measures for the operator to keep an eye on the network’s or object’s performance in an RF circuit. The purpose of the following research includes analyzing the capabilities of NetFlow analyzer to measure various parts, including filters, mixers, frequency sensitive networks, transistors, and other RF-based instruments. NetFlow Analyzer is a network traffic analyzer that measures the network parameters of electrical networks. Although there are other types of network parameter sets including Y, Z, & H-parameters, these instruments are typically employed to measure S-parameters since transmission & reflection of electrical networks are simple to calculate at high frequencies. These analyzers are widely employed to distinguish between two-port networks, including filters and amplifiers. By allowing the user to view the actual data that is sent over a network, packet by packet, a network analyzer informs you of what is happening there. Also, this research will contain the design model of NetFlow Analyzer that Measurements involving transmission and reflection use. Gain, insertion loss, and transmission coefficient are measured in transmission measurements, whereas return loss, reflection coefficient, impedance, and other variables are measured in reflection measurements. These analyzers’ operational frequencies vary from 1 Hz to 1.5 THz. These analyzers can also be used to examine stability in measurements of open loops, audio components, and ultrasonics.展开更多
The pitch angle distributions of ions and electrons can be affected by various processes;thus,they can serve as an important indicator of the physical mechanisms driving the dynamics of space plasmas.From observations...The pitch angle distributions of ions and electrons can be affected by various processes;thus,they can serve as an important indicator of the physical mechanisms driving the dynamics of space plasmas.From observations from the Mars Ion and Neutral Particle Analyzer onboard the Tianwen-1 orbiter,we calculated the pitch angle distributions of protons in the Martian induced magnetosphere by using information from the magnetohydrodynamically simulated magnetic field,and we statistically analyzed the spatial occurrence pattern of different types of pitch angle distributions.Even though no symmetrical features were seen in the dataset,we found the dominance of the field-aligned distribution type over the energy range from 188 to 6232 eV.Maps of the occurrence rate showed the preferential presence of a trapped-like distribution at the lower altitudes of the surveyed nightside region.Although our results are more or less restricted by the adopted magnetic field,they indicate the complexity of the near-Mars proton pitch angle distributions and infer the possibility of wave–particle interactions in the Martian induced magnetosphere.展开更多
火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数...火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数,可有效发现设计中的不合理管径并进行修改。以中东某油田地面工程项目为例,阐述了在工程实际中如何通过该软件进行火炬管网核算。高压火炬管网的核算结果显示,部分安全阀尾管背压和马赫数过大,经软件修改后的尺寸在实际运行中可满足火炬气的排放要求,保证了系统安全。表明了该软件在安全阀的选型和火炬管网的设计工作中的应用价值。展开更多
The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. I...The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. In this study, a self-powered breath analyzer based on polyaniline/polyvinylidene fluoride(PANI/PVDF) piezogas-sensing arrays has been developed for potential detection of several internal diseases. The device works by converting exhaled breath energy into piezoelectric gassensing signals without any external power sources. The five sensing units in the device have different sensitivities to various gas markers with concentrations ranging from 0 to 600 ppm. The working principle can be attributed to the coupling of the in-pipe gas-flow-induced piezoelectric effect of PVDF and gas-sensing properties of PANI electrodes. In addition, the device demonstrates its use as an ethanol analyzer to roughly mimic fatty liver diagnosis.This new approach can be applied to fabricating new exhaled breath analyzers and promoting the development of self-powered systems.展开更多
AIM: To explore the relationship between different parameters of Ocular Response Analyzer(ORA) and Corvis ST(CST) in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 ...AIM: To explore the relationship between different parameters of Ocular Response Analyzer(ORA) and Corvis ST(CST) in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 instruments against intraocular pressure(IOP), measured by the Goldmann applanation tonometer(GAT-IOP), age and gender, and find possible correlation between ORA and CST with GAT.METHODS: This cross-sectional study included 90 healthy children. A general interview and complete eye examination were performed. Following successful GATIOP measurement, ORA and CST were conducted. The CST parameters were A 1/2 length(A1 L, A2 L), A 1/2 velocity(A1 V, A2 V), highest concavity deformation amplitude(HCDA), radius of curvature(Ro C), peak distance(PD), central corneal thickness(CCT) and IOP. The ORA parameters were corneal hysteresis(CH), corneal resistance factor(CRF), Goldmann-correlated IOP(IOP-G) and corneal compensated IOP(IOP-CC). Extracted data was analyzed using the Statistical Package for Social Science software.RESULTS: Totally 39 males with age of 9.08±1.60(6-12)y and 51 females with age of 8.96±1.55(6-13)y were included. Many CST parameters were significantly correlated with CH, CRF, IOP-G and IOP-CC. Some CST parameters had a significant correlation with GAT-IOP, including IOP-CST in both eyes and HCDA, A2 L, PD, and RoC in the left eye, but none with age, except A2 L in the right eye. The CRF measurement showed a significant correlation with GAT-IOP in both eyes and CH in the right eye, yet, none with age. Among all CST and ORA parameters, CCT-CST in both eyes and A1 L in right eye had a significant correlation with gender, although this was a negligible negative correlation. Comparison of mean IOP values by different devices showed a significantly highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Also, IOP-G versus IOP-CST significantly had the lowest IOP overestimation among others. Overall, either low positive correlation or negligible correlation was found between IOP measurements by 3 instruments.CONCLUSION: The study finds the highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Overall, either low positive correlation or negligible correlation is found between IOP measurements by the 3 instruments.展开更多
A conventional multi-channel pulse amplitude analyzer acquires single energy spectrum,but provides no information on its tendency with time.To address the limitation,we propose a scheme of time-sharing multichannel pu...A conventional multi-channel pulse amplitude analyzer acquires single energy spectrum,but provides no information on its tendency with time.To address the limitation,we propose a scheme of time-sharing multichannel pulse amplitude analyzer(TSMCA).A dual-port random access memory is divided into two storage spaces,one for current energy spectrum data acquisition and another for previous energy spectrum data storage.The two tasks can be performed simultaneously,and the time-related variation tendency of energy spectrum can be obtained.A prototype system of TSMCA is designed.It performs nicely,with maximum channel number of 4096 in capacity of 2^(32)/Ch,minimal time-sharing slice of 25 ms,the differential nonlinearity of <1.5%,and the integral nonlinearity of <0.3%.展开更多
The main objective of the Mars Ion and Neutral Particle Analyzer(MINPA)aboard the Chinese Mars Exploration Mission(Tianwen-1)is to study the solar wind-Mars interaction by measuring the ions and energetic neutral atom...The main objective of the Mars Ion and Neutral Particle Analyzer(MINPA)aboard the Chinese Mars Exploration Mission(Tianwen-1)is to study the solar wind-Mars interaction by measuring the ions and energetic neutral atoms(ENAs)near Mars.The MINPA integrates ion and ENA measurements into one sensor head,sharing the same electronics box.The MINPA utilizes a standard toroidal top-hat electrostatic analyzer(ESA)followed by a time of flight(TOF)unit to provide measurement of ions with energies from 2.8 eV to 25.9 keV and ENAs from 50 eV to 3 keV with a base time resolution of 4 seconds.Highly polished silicon single crystal substrates with an Al2O3 film coating are used to ionize the ENAs into positive ions.These ions can then be analyzed by the ESA and TOF,to determine the energy and masses of the ENAs.The MINPA provides a 360°×90°field of view(FOV)with 22.5°×5.4°angular resolution for ion measurement,and a 360°×9.7°FOV with 22.5°×9.7°angular resolution for ENA measurement.The TOF unit combines a-15 kV acceleration high voltage with ultra-thin carbon foils to resolve H+,He2+,He+,O+,O2+and CO2+for ion measurement and to resolve H and O(≥16 amu group)for ENA measurement.Here we present the design principle and describe our ground calibration of the MINPA.展开更多
Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,suc...Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,such as its hydrogen content,composition,viscosity,hydrogen index(HI),mud filtrate invasion,gas to oil ratio,average velocity,velocity distribution etc.,in the situations of in situ downhole or surface Petro-pipelines.In this review article,we focus on the design principle,manufacturing,implementation,methodology and applications of NMR fluid analyzer to oil and gas industry.A detailed description of the state-of-art NMR fluid analyzers was firstly given to exhibit their respective characteristics.With these experiences on hand,we introduced a series of NMR fluid analyzers designed by us at China University of Petroleum-Beijing with continuous optimizations,in terms of magnet construction,antenna layout,circuit design and operating surroundings.These systems discussed in this article have been demonstrated to achieve multiple NMR parameter acquisition when the fluid is in stationary or flowing state.In the end,a prototype was fabricated and validated considering a vast of engineering influences,such as variable temperatures in a large range,high pressure,limited volume,detection efficiency,etc.A particular emphasis of this paper is to expedite the measurement efficiency of the NMR fluid analyzer to reduce the operation costs.This dilemma can be Figured out by upgrading both pulse sequence and observational mode.For different fluid states,two rapid pulse sequences were proposed to sufficiently obtain the multi-dimensional NMR correlation map.Meanwhile,two observational modes were developed to take full advantage of the polarization time,during which the individual antenna was systematically switched.Another domain of interest in this review concerns the applications of this new tool.For stationary fluids case,accurate identification of fluid properties is of great value for scheme building in oil and gas exploration process.Particularly,it can acquire the fluid content by different NMR responses of different components.In addition,with Bloembergen theory and Stokes-Einstein equation,not only molecular dynamics and composition,but also oil viscosity can be readily evaluated.Moreover,HI information of crude oils will be speculated through partial least square regression.As for flowing fluids case,velocity is a significant parameter to understand the in situ fluid exploitation and therefore evaluate the productivity of certain oil wells or pipelines.Regarding to the unique magnet and antenna designs in our NMR fluid analyzer;this review adopts two distinct methods to obtain flow velocity at a wide rating scale.The first one is a time-of-flight method adaptive in a homogeneous magnetic field,which is suitable in the case of fluid at high flow velocity.The other one relies on the adjacent echo phase difference at a magnetic field with constant gradient,which is preferred for relatively low flow velocity.In the near future,this tool will be tested underground to offer individual fluid velocities by combining both the stationary and flowing analysis methods.展开更多
Readout electronics is developed for a prototype time-of-flight(TOF) ion composition spectrometer for in situ measurement of the mass/charge distributions of major ion species from 200 to 100 ke V/e in space plasma.By...Readout electronics is developed for a prototype time-of-flight(TOF) ion composition spectrometer for in situ measurement of the mass/charge distributions of major ion species from 200 to 100 ke V/e in space plasma.By utilizing a constant fraction discriminator(CFD) and time-to-digital converter(TDC), challenging dynamic range measurements were performed with high time resolution and event rates. CFD was employed to discriminate the TOF signals from the micro-channel plate and channel electron multipliers. TDC based on the combination of counter and OR-gate delay chain was designed in a highreliability flash field programmable gate array. Owing to the non-uniformity of the delay chain, a correction algorithm based on integral nonlinearity compensation was implemented to reduce the time uncertainty. The test results showed that the electronics achieved a low timingerror of < 200 ps in the input range from 35 to 500 m V for the CFD, and a time resolution of ～550 ps with time uncertainty < 180 ps after correction and a time range of6.4 ls for the TDC. The TOF spectrum from an electron beam experiment of the impacting N_2 gas further indicated the good performance of this readout electronic.展开更多
The neutral particle analyzer(NPA)is one of the crucial diagnostic devices in a Tokamak facility.The stripping unit is one of the main parts of the NPA.A windowless gas-stripping room with two differential pipes has b...The neutral particle analyzer(NPA)is one of the crucial diagnostic devices in a Tokamak facility.The stripping unit is one of the main parts of the NPA.A windowless gas-stripping room with two differential pipes has been constructed in a parallel electric and magnetic fields(E//B)NPA.The pressure distributions in the stripping chamber are simulated by ANSYS Fluent together with MolFlow+.Based on the pressure distributions obtained from the simulation,the stripping efficiency of the E//B NPA is studied using GEANT4.Hadron reaction physics is modified to track the charge state of each particle in a cross-section-based method in GEANT4.The transmission rates(R)and stripping efficiencies f_(+1)are examined for particle energies ranging from 20 to 200 keV with the input pressure(P_(0)),ranging from 20 to 400 Pa.According to the combined global efficiency,R×f_(+1),P_(0)=240 Pa is obtained as the optimum pressure for the maximum global efficiency in the incident energy range investigated.展开更多
基金supported by the National Natural Science Foundation of China (grant no.62305083 to W.Z.,grant no.T2222009 to H.L.,grant no.32227802 to H.L.)China Postdoctoral Science Foundation (grant no.2023T160163 to W.Z.grant no.2022M720971 to W.Z.)+2 种基金the Heilongjiang Provincial Postdoctoral Science Foundation (grant no.LBH-Z22027 to W.Z.)the National Key Research and Development Program of China (grant no.2022YFC3400600 to H.L.)the Natural Science Foundation of Heilongjiang Province (grant no.YQ2021F013 to H.L.).
文摘A critical function of flow cytometry is to count the concentration of blood cells,which helps in the diagnosis of certain diseases.However,the bulky nature of commercial flow cytometers makes such tests only available in hospitals or laboratories,hindering the spread of point-of-care testing(POCT),especially in underdeveloped areas.Here,we propose a smart Palm-size Optofluidic Hematology Analyzer based on a miniature fluorescence microscope and a microfluidic platform to lighten the device to improve its portability.This gadget has a dimension of 35×30×80 mm and a mass of 39 g,less than 5%of the weight of commercially available flow cytometers.Additionally,automatic leukocyte concentration detection has been realized through the integration of image processing and leukocyte counting algorithms.We compared the leukocyte concentration measurement between our approach and a hemocytometer using the Passing-Bablok analysis and achieved a correlation coefficient of 0.979.Through Bland-Altman analysis,we obtained the relationship between their differences and mean measurement values and established 95%limits of agreement,ranging from−0.93×10^(3)to 0.94×10^(3)cells/μL.We anticipate that this device can be used widely for monitoring and treating diseases such as HIV and tumors beyond hospitals.
文摘A network analyzer can often comprehend many protocols, which enables it to display talks taking place between hosts over a network. A network analyzer analyzes the device or network response and measures for the operator to keep an eye on the network’s or object’s performance in an RF circuit. The purpose of the following research includes analyzing the capabilities of NetFlow analyzer to measure various parts, including filters, mixers, frequency sensitive networks, transistors, and other RF-based instruments. NetFlow Analyzer is a network traffic analyzer that measures the network parameters of electrical networks. Although there are other types of network parameter sets including Y, Z, & H-parameters, these instruments are typically employed to measure S-parameters since transmission & reflection of electrical networks are simple to calculate at high frequencies. These analyzers are widely employed to distinguish between two-port networks, including filters and amplifiers. By allowing the user to view the actual data that is sent over a network, packet by packet, a network analyzer informs you of what is happening there. Also, this research will contain the design model of NetFlow Analyzer that Measurements involving transmission and reflection use. Gain, insertion loss, and transmission coefficient are measured in transmission measurements, whereas return loss, reflection coefficient, impedance, and other variables are measured in reflection measurements. These analyzers’ operational frequencies vary from 1 Hz to 1.5 THz. These analyzers can also be used to examine stability in measurements of open loops, audio components, and ultrasonics.
基金supported by the National Natural Science Foundation of China(Grant No.42241143)the pre-research projects on Civil Aerospace Technologies(No.D020104)funded by the China National Space Administration.
文摘The pitch angle distributions of ions and electrons can be affected by various processes;thus,they can serve as an important indicator of the physical mechanisms driving the dynamics of space plasmas.From observations from the Mars Ion and Neutral Particle Analyzer onboard the Tianwen-1 orbiter,we calculated the pitch angle distributions of protons in the Martian induced magnetosphere by using information from the magnetohydrodynamically simulated magnetic field,and we statistically analyzed the spatial occurrence pattern of different types of pitch angle distributions.Even though no symmetrical features were seen in the dataset,we found the dominance of the field-aligned distribution type over the energy range from 188 to 6232 eV.Maps of the occurrence rate showed the preferential presence of a trapped-like distribution at the lower altitudes of the surveyed nightside region.Although our results are more or less restricted by the adopted magnetic field,they indicate the complexity of the near-Mars proton pitch angle distributions and infer the possibility of wave–particle interactions in the Martian induced magnetosphere.
文摘火炬气的排放系统设计是一个非常复杂的过程,涉及到各泄放点的背压与管路马赫数的计算。介绍了Aspen Flare System Analyzer模拟软件的特点及应用方法,该软件遵循API的规范要求,通过计算火炬管网中各管段始末点的压力、温度、流速等参数,可有效发现设计中的不合理管径并进行修改。以中东某油田地面工程项目为例,阐述了在工程实际中如何通过该软件进行火炬管网核算。高压火炬管网的核算结果显示,部分安全阀尾管背压和马赫数过大,经软件修改后的尺寸在实际运行中可满足火炬气的排放要求,保证了系统安全。表明了该软件在安全阀的选型和火炬管网的设计工作中的应用价值。
基金supported by the National Natural Science Foundation of China (11674048)the Fundamental Research Funds for the Central Universities (N170505001 and N160502002)Program for Shenyang Youth Science and Technology Innovation Talents (RC170269)
文摘The increasing morbidity of internal diseases poses serious threats to human health and quality of life.Exhaled breath analysis is a noninvasive and convenient diagnostic method to improve the cure rate of patients. In this study, a self-powered breath analyzer based on polyaniline/polyvinylidene fluoride(PANI/PVDF) piezogas-sensing arrays has been developed for potential detection of several internal diseases. The device works by converting exhaled breath energy into piezoelectric gassensing signals without any external power sources. The five sensing units in the device have different sensitivities to various gas markers with concentrations ranging from 0 to 600 ppm. The working principle can be attributed to the coupling of the in-pipe gas-flow-induced piezoelectric effect of PVDF and gas-sensing properties of PANI electrodes. In addition, the device demonstrates its use as an ethanol analyzer to roughly mimic fatty liver diagnosis.This new approach can be applied to fabricating new exhaled breath analyzers and promoting the development of self-powered systems.
基金Supported by deputy dean in research of School of Medicine according to study project and deputy vice chancellor of Shiraz University of Medical Sciences
文摘AIM: To explore the relationship between different parameters of Ocular Response Analyzer(ORA) and Corvis ST(CST) in a sample of healthy Iranian school-aged children and the relationship between parameters of these 2 instruments against intraocular pressure(IOP), measured by the Goldmann applanation tonometer(GAT-IOP), age and gender, and find possible correlation between ORA and CST with GAT.METHODS: This cross-sectional study included 90 healthy children. A general interview and complete eye examination were performed. Following successful GATIOP measurement, ORA and CST were conducted. The CST parameters were A 1/2 length(A1 L, A2 L), A 1/2 velocity(A1 V, A2 V), highest concavity deformation amplitude(HCDA), radius of curvature(Ro C), peak distance(PD), central corneal thickness(CCT) and IOP. The ORA parameters were corneal hysteresis(CH), corneal resistance factor(CRF), Goldmann-correlated IOP(IOP-G) and corneal compensated IOP(IOP-CC). Extracted data was analyzed using the Statistical Package for Social Science software.RESULTS: Totally 39 males with age of 9.08±1.60(6-12)y and 51 females with age of 8.96±1.55(6-13)y were included. Many CST parameters were significantly correlated with CH, CRF, IOP-G and IOP-CC. Some CST parameters had a significant correlation with GAT-IOP, including IOP-CST in both eyes and HCDA, A2 L, PD, and RoC in the left eye, but none with age, except A2 L in the right eye. The CRF measurement showed a significant correlation with GAT-IOP in both eyes and CH in the right eye, yet, none with age. Among all CST and ORA parameters, CCT-CST in both eyes and A1 L in right eye had a significant correlation with gender, although this was a negligible negative correlation. Comparison of mean IOP values by different devices showed a significantly highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Also, IOP-G versus IOP-CST significantly had the lowest IOP overestimation among others. Overall, either low positive correlation or negligible correlation was found between IOP measurements by 3 instruments.CONCLUSION: The study finds the highest IOP overestimation by CST and lowest by IOP-CC compared with GAT. Overall, either low positive correlation or negligible correlation is found between IOP measurements by the 3 instruments.
基金supported by the National Natural Science Foundation of China(Nos.11375195,11375263,and 11105143)the project of National Magnetic Confinement Fusion Energy Development Research(No.2013GB104003)
文摘A conventional multi-channel pulse amplitude analyzer acquires single energy spectrum,but provides no information on its tendency with time.To address the limitation,we propose a scheme of time-sharing multichannel pulse amplitude analyzer(TSMCA).A dual-port random access memory is divided into two storage spaces,one for current energy spectrum data acquisition and another for previous energy spectrum data storage.The two tasks can be performed simultaneously,and the time-related variation tendency of energy spectrum can be obtained.A prototype system of TSMCA is designed.It performs nicely,with maximum channel number of 4096 in capacity of 2^(32)/Ch,minimal time-sharing slice of 25 ms,the differential nonlinearity of <1.5%,and the integral nonlinearity of <0.3%.
基金funded by the Chinese National Space Administration.
文摘The main objective of the Mars Ion and Neutral Particle Analyzer(MINPA)aboard the Chinese Mars Exploration Mission(Tianwen-1)is to study the solar wind-Mars interaction by measuring the ions and energetic neutral atoms(ENAs)near Mars.The MINPA integrates ion and ENA measurements into one sensor head,sharing the same electronics box.The MINPA utilizes a standard toroidal top-hat electrostatic analyzer(ESA)followed by a time of flight(TOF)unit to provide measurement of ions with energies from 2.8 eV to 25.9 keV and ENAs from 50 eV to 3 keV with a base time resolution of 4 seconds.Highly polished silicon single crystal substrates with an Al2O3 film coating are used to ionize the ENAs into positive ions.These ions can then be analyzed by the ESA and TOF,to determine the energy and masses of the ENAs.The MINPA provides a 360°×90°field of view(FOV)with 22.5°×5.4°angular resolution for ion measurement,and a 360°×9.7°FOV with 22.5°×9.7°angular resolution for ENA measurement.The TOF unit combines a-15 kV acceleration high voltage with ultra-thin carbon foils to resolve H+,He2+,He+,O+,O2+and CO2+for ion measurement and to resolve H and O(≥16 amu group)for ENA measurement.Here we present the design principle and describe our ground calibration of the MINPA.
基金supported by National Natural Science Foundation of China(Grant Nos.21427812,41674137,51974337)National Science and Technology Major Project of China(2017ZX05019002-008)+1 种基金National"111 Project"(B13010)"863 Project"(2013AA064605)。
文摘Tremendous progress of developing nuclear magnetic resonance(NMR)fluid analyzer has been witnessed in the oil industry for last two decades.This device allows extensive and accurate exploration of fluid properties,such as its hydrogen content,composition,viscosity,hydrogen index(HI),mud filtrate invasion,gas to oil ratio,average velocity,velocity distribution etc.,in the situations of in situ downhole or surface Petro-pipelines.In this review article,we focus on the design principle,manufacturing,implementation,methodology and applications of NMR fluid analyzer to oil and gas industry.A detailed description of the state-of-art NMR fluid analyzers was firstly given to exhibit their respective characteristics.With these experiences on hand,we introduced a series of NMR fluid analyzers designed by us at China University of Petroleum-Beijing with continuous optimizations,in terms of magnet construction,antenna layout,circuit design and operating surroundings.These systems discussed in this article have been demonstrated to achieve multiple NMR parameter acquisition when the fluid is in stationary or flowing state.In the end,a prototype was fabricated and validated considering a vast of engineering influences,such as variable temperatures in a large range,high pressure,limited volume,detection efficiency,etc.A particular emphasis of this paper is to expedite the measurement efficiency of the NMR fluid analyzer to reduce the operation costs.This dilemma can be Figured out by upgrading both pulse sequence and observational mode.For different fluid states,two rapid pulse sequences were proposed to sufficiently obtain the multi-dimensional NMR correlation map.Meanwhile,two observational modes were developed to take full advantage of the polarization time,during which the individual antenna was systematically switched.Another domain of interest in this review concerns the applications of this new tool.For stationary fluids case,accurate identification of fluid properties is of great value for scheme building in oil and gas exploration process.Particularly,it can acquire the fluid content by different NMR responses of different components.In addition,with Bloembergen theory and Stokes-Einstein equation,not only molecular dynamics and composition,but also oil viscosity can be readily evaluated.Moreover,HI information of crude oils will be speculated through partial least square regression.As for flowing fluids case,velocity is a significant parameter to understand the in situ fluid exploitation and therefore evaluate the productivity of certain oil wells or pipelines.Regarding to the unique magnet and antenna designs in our NMR fluid analyzer;this review adopts two distinct methods to obtain flow velocity at a wide rating scale.The first one is a time-of-flight method adaptive in a homogeneous magnetic field,which is suitable in the case of fluid at high flow velocity.The other one relies on the adjacent echo phase difference at a magnetic field with constant gradient,which is preferred for relatively low flow velocity.In the near future,this tool will be tested underground to offer individual fluid velocities by combining both the stationary and flowing analysis methods.
基金supported by the National Key Scientific Instrument and Equipment Development Projects of the National Natural Science Foundation of China(No.41327802)China Mars Project
文摘Readout electronics is developed for a prototype time-of-flight(TOF) ion composition spectrometer for in situ measurement of the mass/charge distributions of major ion species from 200 to 100 ke V/e in space plasma.By utilizing a constant fraction discriminator(CFD) and time-to-digital converter(TDC), challenging dynamic range measurements were performed with high time resolution and event rates. CFD was employed to discriminate the TOF signals from the micro-channel plate and channel electron multipliers. TDC based on the combination of counter and OR-gate delay chain was designed in a highreliability flash field programmable gate array. Owing to the non-uniformity of the delay chain, a correction algorithm based on integral nonlinearity compensation was implemented to reduce the time uncertainty. The test results showed that the electronics achieved a low timingerror of < 200 ps in the input range from 35 to 500 m V for the CFD, and a time resolution of ～550 ps with time uncertainty < 180 ps after correction and a time range of6.4 ls for the TDC. The TOF spectrum from an electron beam experiment of the impacting N_2 gas further indicated the good performance of this readout electronic.
基金This work was supported by the National MCF Energy R&D Program of China(No.MOST 2018YFE0310200)the National Natural Science Foundation of China(Nos.11805138 and 11705242)the Fundamental Research Funds For the Central Universities(Nos.YJ201820 and YJ201954)。
文摘The neutral particle analyzer(NPA)is one of the crucial diagnostic devices in a Tokamak facility.The stripping unit is one of the main parts of the NPA.A windowless gas-stripping room with two differential pipes has been constructed in a parallel electric and magnetic fields(E//B)NPA.The pressure distributions in the stripping chamber are simulated by ANSYS Fluent together with MolFlow+.Based on the pressure distributions obtained from the simulation,the stripping efficiency of the E//B NPA is studied using GEANT4.Hadron reaction physics is modified to track the charge state of each particle in a cross-section-based method in GEANT4.The transmission rates(R)and stripping efficiencies f_(+1)are examined for particle energies ranging from 20 to 200 keV with the input pressure(P_(0)),ranging from 20 to 400 Pa.According to the combined global efficiency,R×f_(+1),P_(0)=240 Pa is obtained as the optimum pressure for the maximum global efficiency in the incident energy range investigated.
