期刊文献+
共找到2篇文章
< 1 >
每页显示 20 50 100
Mechanical Behaviour of Composite Bioactive Bone Cements Consisting of Two Different Types of Surface Treated Hydroxyapatite as Filler
1
作者 S Deb JA Roether 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2005年第B12期10-12,共3页
Bioactive bone cements based on a paste-paste system for orthopaedic applications were developed consisting of hydroxyapatite ( HA ) filler panicles in a methacrylate matrix comprising urethane dimethacrylate ( UD... Bioactive bone cements based on a paste-paste system for orthopaedic applications were developed consisting of hydroxyapatite ( HA ) filler panicles in a methacrylate matrix comprising urethane dimethacrylate ( UDMA ) and triethylene glycol dimethacrylate ( TEGDMA ). To improve the interface between inorganic filler and organic matrix the HA panicles were subjected to two different surface treatment methods, using polyacrylic acid (PAA) and γ-methacryloxy propyl trimethoxy silane (γMPS). The aim of the present study was to determine the influence of surface treatment and the inclusion of multifunctional methacrylates on the mechanical properties, namely 3-point flexural strength (FS) and fracture toughness of the cements and the effect of ageing in simulated body fluid. Comparing the mechanical properties of the two cements, the γMPS- HA cement showed that the fracture toughness of the experimental bone cements were significantly greater ( p 〈 0.001) compared to that of the PMMA cement, whereas PAA-HA containing cement had strength vollues around 20% lower. Interestingly, PAA was found to be more effective in improving the interface as the PAA treated HA cement ( UTHAPPA ) maintained its strength on immersion in SBF, suggesting that PAA provided a coupling, which was less sensitive to moisture, a similar trend was also observed with the inclusion of the carboxyl containing multifunctional methacrylates. 展开更多
关键词 bioactive bone cements coupling agents COMPOSITES polyacrylic acid
下载PDF
Development and clinical trial of a novel bioactive bone cement
2
作者 John CY LEONG Zhaoyang LI William W LU 《Frontiers of Medicine》 SCIE CSCD 2008年第2期117-126,共10页
Strontium(Sr)and related compounds have become more attractive in the prevention and treatment of osteoporosis.Previously,we developed a novel bioactive bone cement which is mainly composed of strontium-con-taining hy... Strontium(Sr)and related compounds have become more attractive in the prevention and treatment of osteoporosis.Previously,we developed a novel bioactive bone cement which is mainly composed of strontium-con-taining hydroxyapatite(Sr-HA)filler and bisphenol A diglycidylether dimethacrylate(Bis-GMA)resin.This bone cement is superior to conventional polymethylmethacrylate(PMMA)bone cement in bioactivity,biocompatibility,and osseointegration.It also has shown sufficient mechanical strength properties for its use in percutaneous vertebro-plasty(PVP)and total hip replacement(THR).In this paper,we review the in vitro,in vivo and clinical evidence for the effectiveness of this bioactive bone cement. 展开更多
关键词 STRONTIUM OSTEOPOROSIS bioactive bone cement VERTEBROPLASTY total hip replacement
原文传递
上一页 1 下一页 到第
使用帮助 返回顶部