Using lactic acid bacteria(LAB)to ferment Huyou peel and pomace could provide a reference for making full use of Huyou resources and provide valuable suggestions for the industrial production of functional foods.The e...Using lactic acid bacteria(LAB)to ferment Huyou peel and pomace could provide a reference for making full use of Huyou resources and provide valuable suggestions for the industrial production of functional foods.The effects of LAB fermentation on the bioactive composition,volatile compounds and antioxidant activity of Huyou peel and pomace were studied.Results showed that both Huyou peel and pomace were good substrates for LAB growth.LAB had remarkable influence on bioconversion of organic acids,among which ascorbic acid content was increased significantly.In addition,LAB could produce flavonoids with enhanced bioactivity and absorption.In particular,the contents of rhoifolin,quercitrin and quercetin were increased by over 100%.Besides,the volatile compounds contents and aroma complexity were improved.Furthermore,the antioxidant activity was enhanced.Thus,our study provides high-value applications of Huyou,and fermented products with improved nutritional value and flavor are potentially beneficial to human health.展开更多
Several gelatin-silicate composites, with or without incorporation of Ca2+ ions, were synthesized through sol-gel processing starting from gelatin and 3- (glycidoxypropyl) trimethoxysilane. The structure around the Si...Several gelatin-silicate composites, with or without incorporation of Ca2+ ions, were synthesized through sol-gel processing starting from gelatin and 3- (glycidoxypropyl) trimethoxysilane. The structure around the Si atoms was similar for all the samples. The measurement of viscoelastic properties indicated that the glass transition temperature and activation energy decreased with the incorporation of Ca2+ ions. The Ca2+ ion-containing composites were bioactive as they spontaneously deposited apatite when soaked in a simulated body fluid of the Kokubo recipe.展开更多
Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect cur...Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect current treatment options and clinical demand for bone grafts continues to rise due to conditions such as trauma,cancer,infection and arthritis.Developing bioactive three-dimensional(3D)scaffolds to support bone regeneration has therefore become a key area of focus within bone tissue engineering(BTE).A variety of materials and manufacturing methods including 3D printing have been used to create novel alternatives to traditional bone grafts.However,individual groups of materials including polymers,ceramics and hydrogels have been unable to fully replicate the properties of bone when used alone.Favourable material properties can be combined and bioactivity improved when groups of materials are used together in composite 3D scaffolds.This review will therefore consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers,hydrogels,metals,ceramics and bio-glasses in BTE.Scaffold fabrication methodology,mechanical performance,biocompatibility,bioactivity,and potential clinical translations will be discussed.展开更多
基金supported by the‘Pioneer'and‘Leading Goose'R&D Program of Zhejiang(No.2022C02012),China.
文摘Using lactic acid bacteria(LAB)to ferment Huyou peel and pomace could provide a reference for making full use of Huyou resources and provide valuable suggestions for the industrial production of functional foods.The effects of LAB fermentation on the bioactive composition,volatile compounds and antioxidant activity of Huyou peel and pomace were studied.Results showed that both Huyou peel and pomace were good substrates for LAB growth.LAB had remarkable influence on bioconversion of organic acids,among which ascorbic acid content was increased significantly.In addition,LAB could produce flavonoids with enhanced bioactivity and absorption.In particular,the contents of rhoifolin,quercitrin and quercetin were increased by over 100%.Besides,the volatile compounds contents and aroma complexity were improved.Furthermore,the antioxidant activity was enhanced.Thus,our study provides high-value applications of Huyou,and fermented products with improved nutritional value and flavor are potentially beneficial to human health.
文摘Several gelatin-silicate composites, with or without incorporation of Ca2+ ions, were synthesized through sol-gel processing starting from gelatin and 3- (glycidoxypropyl) trimethoxysilane. The structure around the Si atoms was similar for all the samples. The measurement of viscoelastic properties indicated that the glass transition temperature and activation energy decreased with the incorporation of Ca2+ ions. The Ca2+ ion-containing composites were bioactive as they spontaneously deposited apatite when soaked in a simulated body fluid of the Kokubo recipe.
文摘Bone is the second most commonly transplanted tissue worldwide,with over four million operations using bone grafts or bone substitute materials annually to treat bone defects.However,significant limitations affect current treatment options and clinical demand for bone grafts continues to rise due to conditions such as trauma,cancer,infection and arthritis.Developing bioactive three-dimensional(3D)scaffolds to support bone regeneration has therefore become a key area of focus within bone tissue engineering(BTE).A variety of materials and manufacturing methods including 3D printing have been used to create novel alternatives to traditional bone grafts.However,individual groups of materials including polymers,ceramics and hydrogels have been unable to fully replicate the properties of bone when used alone.Favourable material properties can be combined and bioactivity improved when groups of materials are used together in composite 3D scaffolds.This review will therefore consider the ideal properties of bioactive composite 3D scaffolds and examine recent use of polymers,hydrogels,metals,ceramics and bio-glasses in BTE.Scaffold fabrication methodology,mechanical performance,biocompatibility,bioactivity,and potential clinical translations will be discussed.
