In the present investigation,measurement of leukocyte chemiluminescence (CL) wasundertaken using micro-whole blood assay in 76 patients with coronary heart diseases (CHDs).The findings showed that there was a signific...In the present investigation,measurement of leukocyte chemiluminescence (CL) wasundertaken using micro-whole blood assay in 76 patients with coronary heart diseases (CHDs).The findings showed that there was a significant increase in leukocyte CL in patients with un-stable angina pectoris (UAP) and acute myocardial infarction (AM1) (P【0.01) and the in-crease was greater in AMI than that in UAP (P【0,01).It was found that leukocyte CL inAMI was correlated with the extent of the infarct and increased with the size of the infarct.Leukocyte CL in AMI patients who had received fibrinolytic treatment was markedly greaterthan that before treatment (P【0.05),suggesting that leukocytes may play an important rolein the pathogenesis of CHDs and may be involved in myocardial ischemia-reperfusion induced in-jury.The findings of the present study demonstrate that measurement of leukocyte CL may beof benefits for prognosis and treatment of CHDs.展开更多
The generation and transformation of radicals on the cathode of indirect electrochemical oxidation were studied by chemilumines- cence(CL)and UV-Visible spectra in the reactor with a salt bridge that connected the sep...The generation and transformation of radicals on the cathode of indirect electrochemical oxidation were studied by chemilumines- cence(CL)and UV-Visible spectra in the reactor with a salt bridge that connected the separated chambers.The CL intensity of 4×10^(-9)mol/L luminol on the cathode with bubbling oxygen was about seven times that of the intensity without it,which was because of the generation of reactive oxygen species(ROS).The existence of ROS,especially the generation of the superoxide radical,c...展开更多
A variety of luminol derivatives with N-and O-substitution have been synthesized with broad functional group tolerance. O-esterification has been demonstrated for the first time as a promising way to prepare enhanced ...A variety of luminol derivatives with N-and O-substitution have been synthesized with broad functional group tolerance. O-esterification has been demonstrated for the first time as a promising way to prepare enhanced CL reagents for sensing hemin, bloodstain and horseradish peroxidase(HRP). The most effective analogue with a deuterated acetyl group exhibited greater potential than luminol for bloodstain imaging and HRP imaging in western blotting(WB). In addition, O-etherification can greatly suppress CL signal that has been applied to design a CL probe for β-glucosidase(β-Glu). This study offers important and useful information regarding the luminol modification and shows great potential to use O-substituted analogues for enhanced CL analysis.展开更多
Graphitic carbon nitride(g-C3N4)has attracted considerable attention due to its special structure and properties,such as its good chemical and thermal stability under ambient conditions,low cost and non-toxicity,and f...Graphitic carbon nitride(g-C3N4)has attracted considerable attention due to its special structure and properties,such as its good chemical and thermal stability under ambient conditions,low cost and non-toxicity,and facile synthesis.Recently,g-C3N4-based sensors have been demonstrated to be of high interests in the areas of sensing due to the unique optical,electronic and catalytic properties of g-C3N4.This review focuses on the most salient advances in luminescent sensors based on g-C3N4,chemiluminescence,cataluminescence and electrochemiluminescence methods are discussed.This review provides valuable information for researchers of related areas and thus may inspire the development of more practical and effective approaches for designing two-dimensional(2D)nanomaterial-assisted luminescent sensors.展开更多
文摘In the present investigation,measurement of leukocyte chemiluminescence (CL) wasundertaken using micro-whole blood assay in 76 patients with coronary heart diseases (CHDs).The findings showed that there was a significant increase in leukocyte CL in patients with un-stable angina pectoris (UAP) and acute myocardial infarction (AM1) (P【0.01) and the in-crease was greater in AMI than that in UAP (P【0,01).It was found that leukocyte CL inAMI was correlated with the extent of the infarct and increased with the size of the infarct.Leukocyte CL in AMI patients who had received fibrinolytic treatment was markedly greaterthan that before treatment (P【0.05),suggesting that leukocytes may play an important rolein the pathogenesis of CHDs and may be involved in myocardial ischemia-reperfusion induced in-jury.The findings of the present study demonstrate that measurement of leukocyte CL may beof benefits for prognosis and treatment of CHDs.
文摘The generation and transformation of radicals on the cathode of indirect electrochemical oxidation were studied by chemilumines- cence(CL)and UV-Visible spectra in the reactor with a salt bridge that connected the separated chambers.The CL intensity of 4×10^(-9)mol/L luminol on the cathode with bubbling oxygen was about seven times that of the intensity without it,which was because of the generation of reactive oxygen species(ROS).The existence of ROS,especially the generation of the superoxide radical,c...
基金projects of the Department of Education of Guangdong Province(Nos.2021ZDZX2030 and 2020ZDZX2017)Guangdong Basic and Applied Basic Research Foundation(No.2021A1515110115)Guangzhou Basic and Applied Basic Research Foundation(No.202102020548)for funding support。
文摘A variety of luminol derivatives with N-and O-substitution have been synthesized with broad functional group tolerance. O-esterification has been demonstrated for the first time as a promising way to prepare enhanced CL reagents for sensing hemin, bloodstain and horseradish peroxidase(HRP). The most effective analogue with a deuterated acetyl group exhibited greater potential than luminol for bloodstain imaging and HRP imaging in western blotting(WB). In addition, O-etherification can greatly suppress CL signal that has been applied to design a CL probe for β-glucosidase(β-Glu). This study offers important and useful information regarding the luminol modification and shows great potential to use O-substituted analogues for enhanced CL analysis.
基金the National Natural Science Foundation of China[nos.21405107 and 21375089].
文摘Graphitic carbon nitride(g-C3N4)has attracted considerable attention due to its special structure and properties,such as its good chemical and thermal stability under ambient conditions,low cost and non-toxicity,and facile synthesis.Recently,g-C3N4-based sensors have been demonstrated to be of high interests in the areas of sensing due to the unique optical,electronic and catalytic properties of g-C3N4.This review focuses on the most salient advances in luminescent sensors based on g-C3N4,chemiluminescence,cataluminescence and electrochemiluminescence methods are discussed.This review provides valuable information for researchers of related areas and thus may inspire the development of more practical and effective approaches for designing two-dimensional(2D)nanomaterial-assisted luminescent sensors.
