A high thrust-to-weight ratio poses challenges to the high-temperature performance of Ni-based superalloys. The oxidation behavior of GH4738 at extreme temperatures has been investigated by isothermal and non-isotherm...A high thrust-to-weight ratio poses challenges to the high-temperature performance of Ni-based superalloys. The oxidation behavior of GH4738 at extreme temperatures has been investigated by isothermal and non-isothermal experiments. As a result of the competitive diffusion of alloying elements, the oxide scale included an outermost porous oxide layer (OOL), an inner relatively dense oxide layer (IOL), and an internal oxide zone (IOZ), depending on the temperature and time. A high temperature led to the formation of large voids at the IOL/IOZ interface. At 1200℃, the continuity of the Cr-rich oxide layer in the IOL was destroyed, and thus, spallation occurred. Extension of oxidation time contributed to the size of Al-rich oxide particles with the increase in the IOZ. Based on this finding,the oxidation kinetics of GH4738 was discussed, and the corresponding oxidation behavior at 900-1100℃ was predicted.展开更多
BACKGROUND Helicobacter pylori(H.pylori)infects over half the global population,causing gastrointestinal diseases like dyspepsia,gastritis,duodenitis,peptic ulcers,GMALT lymphoma,and gastric adenocarcinoma.Eradicating...BACKGROUND Helicobacter pylori(H.pylori)infects over half the global population,causing gastrointestinal diseases like dyspepsia,gastritis,duodenitis,peptic ulcers,GMALT lymphoma,and gastric adenocarcinoma.Eradicating H.pylori is crucial for treating and preventing these conditions.While conventional proton pump inhibitor(PPI)-based triple therapy is effective,there’s growing interest in longer acid suppression therapies.Potassium competitive acid blocker(P-CAB)triple and dual therapy are new regimens for H.pylori eradication.Initially used in Asian populations,vonoprazan(VPZ)has been recently Food and Drug Administration-approved for H.pylori eradication.AIM To assess the efficacy of regimens containing P-CABs in eradicating H.pylori infection.METHODS This study,following PRISMA 2020 guidelines,conducted a systematic review and meta-analysis by searching MEDLINE and Scopus libraries for randomized clinical trials(RCTs)or observational studies with the following command:[("Helicobacter pylori"OR"H pylori")AND("Treatment"OR"Therapy"OR"Eradication")AND("Vonaprazan"OR"Potassium-Competitive Acid Blocker"OR"P-CAB"OR"PCAB"OR"Revaprazan"OR"Linaprazan"OR"Soraprazan"OR"Tegoprazan")].Studies comparing the efficacy of P-CABs-based treatment to classical PPIs in eradicating H.pylori were included.Exclusion criteria included case reports,case series,unpublished trials,or conference abstracts.Data variables encompassed age,diagnosis method,sample sizes,study duration,intervention and control,and H.pylori eradication method were gathered by two independent reviewers.Meta-analysis was performed in R software,and forest plots were generated.RESULTS A total of 256 references were initially retrieved through the search command.Ultimately,fifteen studies(7 RCTs,7 retrospective observational studies,and 1 comparative unique study)were included,comparing P-CAB triple therapy to PPI triple therapy.The intention-to-treat analysis involved 8049 patients,with 4471 in the P-CAB intervention group and 3578 in the PPI control group across these studies.The analysis revealed a significant difference in H.pylori eradication between VPZ triple therapy and PPI triple therapy in both RCTs and observational studies[risk ratio(RR)=1.17,95%confidence interval(CI):1.11-1.22,P<0.0001]and(RR=1.13,95%CI:1.09-1.17,P<0.0001],respectively.However,no significant difference was found between tegoprazan(TPZ)triple therapy and PPI triple therapy in both RCTs and observational studies(RR=1.04,95%CI:0.93-1.16,P=0.5)and(RR=1.03,95%CI:0.97-1.10,P=0.3),respectively.CONCLUSION VPZ-based triple therapy outperformed conventional PPI-based triple therapy in eradicating H.pylori,positioning it as a highly effective first-line regimen.Additionally,TPZ-based triple therapy was non-inferior to classical PPI triple therapy.展开更多
Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern Ch...Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern China from 2000 to 2018,this study explores the coupling coordination development of port and city environments and its impact on urban economic competitiveness by constructing the coupling coordination degree model and the panel threshold model.The research results show that:(1)In terms of the coupling coordination development of port and city environments,most coastal ports and their hinterland cities are in a state of moderate or serious disorder.Overall,the degree of coupling coordination of port and city environments needs to be further improved;(2)The coupling coordination degree of port and city environments has a significant impact on urban economic competitiveness,and this effect gradually increases with the development of the ports and the urban economy.Among the variables that impact the urban economic competitiveness,fixed assets investment and foreign trade are significant factors that can enhance urban economic competitiveness.(3)At present,there is a“U-shaped”relationship between the coupling coordination degree of port-city environments and the urban economic competitiveness.This relationship lies on the right side of the inflection point of the“U-shaped”curve.Therefore,following the concept of assigning priority to ecological development,expanding fixed assets investment and actively developing foreign trade can further enhance the urban economic competitiveness.展开更多
Based on the analysis of rice planting and export development in Heilongjiang Province in 2013-2021,this paper comprehensively used three export competitiveness analysis methods,namely,trade competitiveness index,reve...Based on the analysis of rice planting and export development in Heilongjiang Province in 2013-2021,this paper comprehensively used three export competitiveness analysis methods,namely,trade competitiveness index,revealed comparative advantage(RCA)analysis and international market share analysis,to compare the four major rice exporters in the world and the three major rice export provinces and cities in China.Besides,it evaluated the rice export competitiveness of Heilongjiang Province from multiple perspectives.It analyzed the reasons for low competitiveness in terms of export product structure,export market structure,production and processing technology,and brand building.Finally,it is recommended to clarify the positioning of rice export quality and take more measures to ensure product quality;improve the level of industrialization of rice production and processing,and extend the rice industry chain;develop diversified rice export markets and improve export flexibility;adhere to the principle of"opening the door and going out",expand the international popularity of high-quality brands,so as to enhance the rice export competitiveness of Heilongjiang Province.展开更多
This work aims to introduce a conceptual approach to determining the competitive environment for a particular tourist destination by considering popular outbound destinations of its leading segments.This approach we n...This work aims to introduce a conceptual approach to determining the competitive environment for a particular tourist destination by considering popular outbound destinations of its leading segments.This approach we name as a concept of a segment-centered geo-competitive environment of a tourism destination(SGE-TD).The applied methodology includes consideration of the popularity of tourist destinations for each selected segment and the indicators of leading segments of the studied destination.The practical application of the proposed concept is examined in the case of Georgia as a tourist destination by selecting its leading segments and identifying their popular travel destinations.The integrated consideration and application of the mentioned indicators define the competitive position of a destination(in this case Georgia)among the specified tourism destinations,considered as the geo-competitive environment.This research suggests an innovative version of the universal conceptual approach to identify the leading competing destinations for a specific studied one.It fills the gap in similar studies where competing destinations for the analysis are selected based on specific research objectives,missing the universal conceptual approach in this regard.展开更多
In this study,the competitive failure mechanism of bolt loosening and fatigue is elucidated via competitive failure tests on bolts under composite excitation.Based on the competitive failure mechanism,the mode predict...In this study,the competitive failure mechanism of bolt loosening and fatigue is elucidated via competitive failure tests on bolts under composite excitation.Based on the competitive failure mechanism,the mode prediction model and“load ratio-life prediction curve”(ξ-N curve)of the bolt competitive failure are established.Given the poor correlation of theξ-N curve,an evaluation model of the bolt competitive failure life is proposed based on Miner’s linear damage accumulation theory.Based on the force analysis of the thread surface and simulation of the bolt connection under composite excitation,a theoretical equation of the bolt competitive failure life is established to validate the model for evaluating the bolt competitive failure life.The results reveal that the proposed model can accurately predict the competitive failure life of bolts under composite excitation,and thereby,it can provide guidance to engineering applications.展开更多
Autism spectrum disorder(ASD),classified as a developmental disability,is now more common in children than ever.A drastic increase in the rate of autism spectrum disorder in children worldwide demands early detection ...Autism spectrum disorder(ASD),classified as a developmental disability,is now more common in children than ever.A drastic increase in the rate of autism spectrum disorder in children worldwide demands early detection of autism in children.Parents can seek professional help for a better prognosis of the child’s therapy when ASD is diagnosed under five years.This research study aims to develop an automated tool for diagnosing autism in children.The computer-aided diagnosis tool for ASD detection is designed and developed by a novel methodology that includes data acquisition,feature selection,and classification phases.The most deterministic features are selected from the self-acquired dataset by novel feature selection methods before classification.The Imperialistic competitive algorithm(ICA)based on empires conquering colonies performs feature selection in this study.The performance of Logistic Regression(LR),Decision tree,K-Nearest Neighbor(KNN),and Random Forest(RF)classifiers are experimentally studied in this research work.The experimental results prove that the Logistic regression classifier exhibits the highest accuracy for the self-acquired dataset.The ASD detection is evaluated experimentally with the Least Absolute Shrinkage and Selection Operator(LASSO)feature selection method and different classifiers.The Exploratory Data Analysis(EDA)phase has uncovered crucial facts about the data,like the correlation of the features in the dataset with the class variable.展开更多
Transgene escape could lead to genetically modified rice establishing wild populations in the natural environment and competing for survival space with weeds.However,whether the expression of the Bacillus thuringiensi...Transgene escape could lead to genetically modified rice establishing wild populations in the natural environment and competing for survival space with weeds.However,whether the expression of the Bacillus thuringiensis(Bt)gene in rice will alter the relationship between transgene plants and weeds and induce undesirable environmental consequences are poorly understood.Thus,field experiments were conducted to investigate the weed competitiveness and assess the ecological risk of transgenic Bt rice under herbicide-free and lepidopterous pest-controlled environments.Results showed that weed–rice competition in the direct-sowing(DS)field was earlier and more severe than that in the transplanting(TP)field,which resulted in a significant decrease in biomass and yield in DS.However,conventional Bt and non-Bt rice yield was not significantly different.The weed number,weed coverage ratio,and weed diversity of conventional Bt rice were significantly higher than those of non-Bt rice at the early growth and mature stages,especially in DS plots,suggesting that Bt traits did not increase the weed competitiveness of transgenic rice and had no negative effect on weed diversity.Grain yield and weed number varied between different hybrid rice lines,but those differences were insignificant between Bt and non-Bt rice.The number of insects increased with the increase of weeds in hybrid rice plots,whereas the insect number and diversity did not display a significant difference between Bt and non-Bt rice.Therefore,the ecological risk of transgenic Bt rice is comparable to non-Bt rice.展开更多
Gyllenberg and Yan(Discrete Contin Dyn Syst Ser B 11(2):347–352,2009)presented a system in Zeeman’s class 30 of 3-dimensional Lotka-Volterra(3D LV)competitive systems to admit at least two limit cycles,one of which ...Gyllenberg and Yan(Discrete Contin Dyn Syst Ser B 11(2):347–352,2009)presented a system in Zeeman’s class 30 of 3-dimensional Lotka-Volterra(3D LV)competitive systems to admit at least two limit cycles,one of which is generated by the Hopf bifurcation and the other is obtained by the Poincaré-Bendixson theorem.Yu et al.(J Math Anal Appl 436:521–555,2016,Sect.3.4)recalculated the first Liapunov coefficient of Gyllenberg and Yan’s system to be positive,rather than negative as in Gyllenberg and Yan(2009),and pointed out that the Poincaré-Bendixson theorem is not applicable for that system.Jiang et al.(J Differ Equ 284:183–218,2021,p.213)proposed an open question:“whether Zeeman’s class 30 can be rigorously proved to admit at least two limit cycles by the Hopf theorem and the Poincaré-Bendixson theorem?”This paper provides four systems in Zeeman’s class 30 to admit at least two limit cycles by the Hopf theorem and the Poincaré-Bendixson theorem and gives an answer to the above question.展开更多
After 5 years of accumulation, Animal Models and Experimental Medicine(AMEM) has received 396 manuscripts from 46 countries and regions, including Chinese mainland, Iran, the United States, India, Israel, Nigeria, Bra...After 5 years of accumulation, Animal Models and Experimental Medicine(AMEM) has received 396 manuscripts from 46 countries and regions, including Chinese mainland, Iran, the United States, India, Israel, Nigeria, Brazil, Bangladesh, Sri Lanka, the Netherlands, Denmark, Australia, Japan, and Spain. It has become an important international exchange and display platform for innovative research results in the field of laboratory animal science and basic medicine.展开更多
With the daily expansion of global energy consumption,developing the power grids is of uttermost importance.However,building a new trans-mission line is costly and time-consuming,so utilizing the same lines with possi...With the daily expansion of global energy consumption,developing the power grids is of uttermost importance.However,building a new trans-mission line is costly and time-consuming,so utilizing the same lines with possible higher transmission capacity is very cost-effective.In this regard,to increase the capacity of the transmission lines,the flexible alternating current transmission system(FACTS)has been widely used in power grids in recent years by industrialized countries.One of the essential topics in electrical power systems is the reactive power compensation,and the FACTS plays a significant role in controlling the reactive power current in the power grid and the system voltage oscillations and stability.When a static synchronous compensator(STATCOM)is embedded in a power system to increase the bus voltage,a supplementary damping controller can be designed to enhance the system oscillation damping.Given the expansion of the grids in the power system,the complexity of their optimization and the extraordinary ability of the imperialist competitive algorithm(ICA)for solving such problems,in this paper,the ICA has been used to determine the optimal position and size of the FACTS devices.展开更多
This work aims to resolve the distributed heterogeneous permutation flow shop scheduling problem(DHPFSP)with minimizing makespan and total energy consumption(TEC).To solve this NP-hard problem,this work proposed a com...This work aims to resolve the distributed heterogeneous permutation flow shop scheduling problem(DHPFSP)with minimizing makespan and total energy consumption(TEC).To solve this NP-hard problem,this work proposed a competitive and cooperative-based strength Pareto evolutionary algorithm(CCSPEA)which contains the following features:1)An initialization based on three heuristic rules is developed to generate a population with great diversity and convergence.2)A comprehensive metric combining convergence and diversity metrics is used to better represent the heuristic information of a solution.3)A competitive selection is designed which divides the population into a winner and a loser swarms based on the comprehensive metric.4)A cooperative evolutionary schema is proposed for winner and loser swarms to accelerate the convergence of global search.5)Five local search strategies based on problem knowledge are designed to improve convergence.6)Aproblem-based energy-saving strategy is presented to reduce TEC.Finally,to evaluate the performance of CCSPEA,it is compared to four state-of-art and run on 22 instances based on the Taillard benchmark.The numerical experiment results demonstrate that 1)the proposed comprehensive metric can efficiently represent the heuristic information of each solution to help the later step divide the population.2)The global search based on the competitive and cooperative schema can accelerate loser solutions convergence and further improve the winner’s exploration.3)The problembased initialization,local search,and energy-saving strategies can efficiently reduce the makespan and TEC.4)The proposed CCSPEA is superior to the state-of-art for solving DHPFSP.展开更多
The climate issue has become an environmental concern for all sectors of the world and the low-carbon economy has thus become a new economic development model to combat climate change.With the development of low-carbo...The climate issue has become an environmental concern for all sectors of the world and the low-carbon economy has thus become a new economic development model to combat climate change.With the development of low-carbon economy era,the textile and clothing industry plays an important role in stabilizing the development of low-carbon economy and society,and China has put forward the development requirements of low-carbon transformation for the textile and clothing industry,and also it has an important strategic value to promote the high-quality development of low-carbon economy and society,and the construction of brands’ core competitiveness is an inevitable choice for clothing brands in the face of the new form of international competition.As a result,the evaluation indicator of clothing brands’ core competitiveness in the low-carbon economy is used to measure the core competitiveness of clothing brands.Based on the corresponding verification results obtained by analytic hierarchy process(AHP) analysis,it can guide the low-carbon development of the clothing industry,thus proposing a more reasonable way to build the core competitiveness of clothing brands.It can promote the low-carbon transformation and upgrading of the clothing industry,effectively increase the market share of clothing brands,and promote the high-quality development of clothing brands.展开更多
Due to the late start of China’s forest health industry,related research is lagging behind,which results in the inability to propose a corresponding path to enhance competitiveness.Based on this,the evaluation index ...Due to the late start of China’s forest health industry,related research is lagging behind,which results in the inability to propose a corresponding path to enhance competitiveness.Based on this,the evaluation index system of provincial forest health industry competitiveness was constructed by using the Porter diamond model,and the Entropy-TOPSIS model is used to evaluate the competitiveness of China’s provincial forest health industry,and the key influencing factors of the forest health industry competitiveness are identified by using the grey correlation analysis method,and the specific promotion path was designed.The empirical results show that the grey correlation degree between related and supporting industries and the competitiveness score of the forest health industry is the highest,which confirms that it is the key influencing factor of the competitiveness of the forest health industry.Therefore,government departments should vigorously promote the integration of cultural tourism,medical care,pension and other related industries with the forest health care industry;enterprises should strengthen the construction of forest health infrastr ucture and supporting facilities to improve the level of forest health services.展开更多
From the perspective of wellbeing performance of ecological input,this paper constructs a low-carbon competitiveness evaluation model with wellbeing performance of carbon emissions as the measurement standard,and uses...From the perspective of wellbeing performance of ecological input,this paper constructs a low-carbon competitiveness evaluation model with wellbeing performance of carbon emissions as the measurement standard,and uses the LMDI factor decomposition method to decompose the total effect of low-carbon competitiveness changes into technology effect and service effect.And then it conducts positive analysis and comparison of the low-carbon competitiveness and its effect contribution of G20 countries from1990 to 2018.The results are as follows:Firstly,in 2018,the UK,France,Argentina,Brazil,and Germany had higher low-carbon competitiveness.From 1990 to 2018,the low-carbon competitiveness of the UK,Turkey,Germany,Italy,and Brazil increase rapidly.Secondly,from 1990 to 2018,the total effect of low-carbon competitiveness of G20 member states was all positive,that is to say,the overall wellbeing performance of carbon emissions increased,technology effect and service effect are positive in 17 countries and negative in 2 countries respectively.Thirdly,China's low-carbon competitiveness is low,lacking static and dynamic advantages,although the technology effect is the highest,but the service effect is the lowest,resulting in a low total effect,which indicates that the wellbeing performance of economic growth is the main bottleneck of China's low-carbon development.Finally,the policy recommendations for China's future low-carbon transition and sustainable development are put forward.展开更多
A mong the eight major steps China announced at the Third Belt and Road Forum for International Cooperation to support high-quality Belt and Road cooperation,the cancelation of all restrictions on foreign investment a...A mong the eight major steps China announced at the Third Belt and Road Forum for International Cooperation to support high-quality Belt and Road cooperation,the cancelation of all restrictions on foreign investment access in the manufacturing sector is the most striking measure,or at least one of the most eye-catching.展开更多
With the economic globalization and the increasingly fierce industrial competition at home and abroad, the importance of industrial competitive intelligence service is becoming increasingly prominent. Under the policy...With the economic globalization and the increasingly fierce industrial competition at home and abroad, the importance of industrial competitive intelligence service is becoming increasingly prominent. Under the policy background of cooperation and sharing, pluralistic coordination has become a new trend in regional economic development. The multi collaborative online service platform of industrial competitive intelligence is jointly constructed by all service subjects. The platform is guided and promoted by the government. Colleges and universities provide support for industrial competitive intelligence theory and professionals, scientific research institutes provide talent and advanced technology support, industry associations are responsible for dynamic monitoring of industrial development, and profit-making institutions are responsible for supplementing industrial competitive intelligence achievements. All service subjects integrate and explore existing intelligence resources and services through the unified online industrial competitive intelligence sharing platform, so as to realize benign cooperation, collaborative management, resource integration, user integration and service integration among subjects, so as to realize multiple collaborative services of industrial competitive intelligence.展开更多
This study focuses on the evolution of growth model and cultivation of competitive advantages under the ambidextrous innovation strategy.After a brief introduction of the connotation of ambidextrous innovation strateg...This study focuses on the evolution of growth model and cultivation of competitive advantages under the ambidextrous innovation strategy.After a brief introduction of the connotation of ambidextrous innovation strategy,the evolution of growth model of high-tech enterprises under the conventional strategy and the ambidextrous innovation strategy is analyzed.Furthermore,a discussion is made on how to cultivate enterprises’competitive advantages under the ambidextrous innovation strategy,thereby enabling enterprises to stand out from competitors under this new strategic model and truly achieve the goal of sustainable development.展开更多
This paper constructs a multiple collaborative service model of industrial competition intelligence with the main purpose of promoting the development of regional industries. The multiple service subjects include ente...This paper constructs a multiple collaborative service model of industrial competition intelligence with the main purpose of promoting the development of regional industries. The multiple service subjects include enterprises, governments, colleges and universities, scientific research institutes, industry associations and for-profit institutions. This article starts from the overall development of regional industrial economy, weighs the mutual relationship between the elements of the service model, and promotes multiple service subjects such as enterprises, governments, universities, research institutes, industry associations, and profit-making organizations to realize the collaborative service of resource intelligence, demand intelligence and data intelligence provides linkage intelligence service for the development and innovation of regional industries. This service model can improve the efficiency of industrial competitive intelligence services and the overall competitiveness of regional industries.展开更多
Objective To analyze the current situation of medicine circulation enterprises and summarize the influence of frequently introduced industry policies on the pharmaceutical field,so as to provide suggestions on improvi...Objective To analyze the current situation of medicine circulation enterprises and summarize the influence of frequently introduced industry policies on the pharmaceutical field,so as to provide suggestions on improving the competitiveness and maintaining sustainable development of medicine circulation enterprises in China.Methods Industry policy analysis,literature inquiry,expert interview and questionnaire survey were used to study the challenges that medicine circulation faced under the new situation.Then,the key indexes were found out to improve its competitiveness.Results and Conclusion Through the analysis of the current situation of the industry,policy orientation and market demand,some suggestions are put forward for related enterprises to improve their competitiveness.展开更多
基金financially supported by the National Key R&D Program of China (No.2021YFB3700400)the National Natural Science Foundation of China (Nos.52074030,51904021,and 52174294)。
文摘A high thrust-to-weight ratio poses challenges to the high-temperature performance of Ni-based superalloys. The oxidation behavior of GH4738 at extreme temperatures has been investigated by isothermal and non-isothermal experiments. As a result of the competitive diffusion of alloying elements, the oxide scale included an outermost porous oxide layer (OOL), an inner relatively dense oxide layer (IOL), and an internal oxide zone (IOZ), depending on the temperature and time. A high temperature led to the formation of large voids at the IOL/IOZ interface. At 1200℃, the continuity of the Cr-rich oxide layer in the IOL was destroyed, and thus, spallation occurred. Extension of oxidation time contributed to the size of Al-rich oxide particles with the increase in the IOZ. Based on this finding,the oxidation kinetics of GH4738 was discussed, and the corresponding oxidation behavior at 900-1100℃ was predicted.
文摘BACKGROUND Helicobacter pylori(H.pylori)infects over half the global population,causing gastrointestinal diseases like dyspepsia,gastritis,duodenitis,peptic ulcers,GMALT lymphoma,and gastric adenocarcinoma.Eradicating H.pylori is crucial for treating and preventing these conditions.While conventional proton pump inhibitor(PPI)-based triple therapy is effective,there’s growing interest in longer acid suppression therapies.Potassium competitive acid blocker(P-CAB)triple and dual therapy are new regimens for H.pylori eradication.Initially used in Asian populations,vonoprazan(VPZ)has been recently Food and Drug Administration-approved for H.pylori eradication.AIM To assess the efficacy of regimens containing P-CABs in eradicating H.pylori infection.METHODS This study,following PRISMA 2020 guidelines,conducted a systematic review and meta-analysis by searching MEDLINE and Scopus libraries for randomized clinical trials(RCTs)or observational studies with the following command:[("Helicobacter pylori"OR"H pylori")AND("Treatment"OR"Therapy"OR"Eradication")AND("Vonaprazan"OR"Potassium-Competitive Acid Blocker"OR"P-CAB"OR"PCAB"OR"Revaprazan"OR"Linaprazan"OR"Soraprazan"OR"Tegoprazan")].Studies comparing the efficacy of P-CABs-based treatment to classical PPIs in eradicating H.pylori were included.Exclusion criteria included case reports,case series,unpublished trials,or conference abstracts.Data variables encompassed age,diagnosis method,sample sizes,study duration,intervention and control,and H.pylori eradication method were gathered by two independent reviewers.Meta-analysis was performed in R software,and forest plots were generated.RESULTS A total of 256 references were initially retrieved through the search command.Ultimately,fifteen studies(7 RCTs,7 retrospective observational studies,and 1 comparative unique study)were included,comparing P-CAB triple therapy to PPI triple therapy.The intention-to-treat analysis involved 8049 patients,with 4471 in the P-CAB intervention group and 3578 in the PPI control group across these studies.The analysis revealed a significant difference in H.pylori eradication between VPZ triple therapy and PPI triple therapy in both RCTs and observational studies[risk ratio(RR)=1.17,95%confidence interval(CI):1.11-1.22,P<0.0001]and(RR=1.13,95%CI:1.09-1.17,P<0.0001],respectively.However,no significant difference was found between tegoprazan(TPZ)triple therapy and PPI triple therapy in both RCTs and observational studies(RR=1.04,95%CI:0.93-1.16,P=0.5)and(RR=1.03,95%CI:0.97-1.10,P=0.3),respectively.CONCLUSION VPZ-based triple therapy outperformed conventional PPI-based triple therapy in eradicating H.pylori,positioning it as a highly effective first-line regimen.Additionally,TPZ-based triple therapy was non-inferior to classical PPI triple therapy.
基金This research is supported by Hunan Provincial Natural Science Foundation of China(Grant No.2021JJ30304)the General Topics of Hunan Social Science Achievement Evaluation Committee of China(Grant No.XSP22YBC366)the Key Scientific Research Project of Hunan Provincial Department of Education of China(Grant No.21B0592).
文摘Promoting the coupling coordination development of port and its hinterland city environments is an important way to improve urban economic competitiveness.Based on relevant data of 13 coastal port cities in eastern China from 2000 to 2018,this study explores the coupling coordination development of port and city environments and its impact on urban economic competitiveness by constructing the coupling coordination degree model and the panel threshold model.The research results show that:(1)In terms of the coupling coordination development of port and city environments,most coastal ports and their hinterland cities are in a state of moderate or serious disorder.Overall,the degree of coupling coordination of port and city environments needs to be further improved;(2)The coupling coordination degree of port and city environments has a significant impact on urban economic competitiveness,and this effect gradually increases with the development of the ports and the urban economy.Among the variables that impact the urban economic competitiveness,fixed assets investment and foreign trade are significant factors that can enhance urban economic competitiveness.(3)At present,there is a“U-shaped”relationship between the coupling coordination degree of port-city environments and the urban economic competitiveness.This relationship lies on the right side of the inflection point of the“U-shaped”curve.Therefore,following the concept of assigning priority to ecological development,expanding fixed assets investment and actively developing foreign trade can further enhance the urban economic competitiveness.
基金Social Science Planning Project of Xi an City(JG140)Bidding Project of Buchang Xixian Economic Research Institute(SMZX202113).
文摘Based on the analysis of rice planting and export development in Heilongjiang Province in 2013-2021,this paper comprehensively used three export competitiveness analysis methods,namely,trade competitiveness index,revealed comparative advantage(RCA)analysis and international market share analysis,to compare the four major rice exporters in the world and the three major rice export provinces and cities in China.Besides,it evaluated the rice export competitiveness of Heilongjiang Province from multiple perspectives.It analyzed the reasons for low competitiveness in terms of export product structure,export market structure,production and processing technology,and brand building.Finally,it is recommended to clarify the positioning of rice export quality and take more measures to ensure product quality;improve the level of industrialization of rice production and processing,and extend the rice industry chain;develop diversified rice export markets and improve export flexibility;adhere to the principle of"opening the door and going out",expand the international popularity of high-quality brands,so as to enhance the rice export competitiveness of Heilongjiang Province.
文摘This work aims to introduce a conceptual approach to determining the competitive environment for a particular tourist destination by considering popular outbound destinations of its leading segments.This approach we name as a concept of a segment-centered geo-competitive environment of a tourism destination(SGE-TD).The applied methodology includes consideration of the popularity of tourist destinations for each selected segment and the indicators of leading segments of the studied destination.The practical application of the proposed concept is examined in the case of Georgia as a tourist destination by selecting its leading segments and identifying their popular travel destinations.The integrated consideration and application of the mentioned indicators define the competitive position of a destination(in this case Georgia)among the specified tourism destinations,considered as the geo-competitive environment.This research suggests an innovative version of the universal conceptual approach to identify the leading competing destinations for a specific studied one.It fills the gap in similar studies where competing destinations for the analysis are selected based on specific research objectives,missing the universal conceptual approach in this regard.
基金Supported by National Natural Science Foundation of China(Grant No.52175123)the Independent Subject of State Key Laboratory of Traction Power(Grant No.2022TPL_T03).
文摘In this study,the competitive failure mechanism of bolt loosening and fatigue is elucidated via competitive failure tests on bolts under composite excitation.Based on the competitive failure mechanism,the mode prediction model and“load ratio-life prediction curve”(ξ-N curve)of the bolt competitive failure are established.Given the poor correlation of theξ-N curve,an evaluation model of the bolt competitive failure life is proposed based on Miner’s linear damage accumulation theory.Based on the force analysis of the thread surface and simulation of the bolt connection under composite excitation,a theoretical equation of the bolt competitive failure life is established to validate the model for evaluating the bolt competitive failure life.The results reveal that the proposed model can accurately predict the competitive failure life of bolts under composite excitation,and thereby,it can provide guidance to engineering applications.
基金The authors extend their appreciation to the Deputyship for Research&Innovation,Ministry of Education in Saudi Arabia for funding this research work through the Project Number(IF2-PSAU-2022/01/22043)。
文摘Autism spectrum disorder(ASD),classified as a developmental disability,is now more common in children than ever.A drastic increase in the rate of autism spectrum disorder in children worldwide demands early detection of autism in children.Parents can seek professional help for a better prognosis of the child’s therapy when ASD is diagnosed under five years.This research study aims to develop an automated tool for diagnosing autism in children.The computer-aided diagnosis tool for ASD detection is designed and developed by a novel methodology that includes data acquisition,feature selection,and classification phases.The most deterministic features are selected from the self-acquired dataset by novel feature selection methods before classification.The Imperialistic competitive algorithm(ICA)based on empires conquering colonies performs feature selection in this study.The performance of Logistic Regression(LR),Decision tree,K-Nearest Neighbor(KNN),and Random Forest(RF)classifiers are experimentally studied in this research work.The experimental results prove that the Logistic regression classifier exhibits the highest accuracy for the self-acquired dataset.The ASD detection is evaluated experimentally with the Least Absolute Shrinkage and Selection Operator(LASSO)feature selection method and different classifiers.The Exploratory Data Analysis(EDA)phase has uncovered crucial facts about the data,like the correlation of the features in the dataset with the class variable.
基金funded by the National Program of Transgenic Variety Development of China(2016ZX08001001)。
文摘Transgene escape could lead to genetically modified rice establishing wild populations in the natural environment and competing for survival space with weeds.However,whether the expression of the Bacillus thuringiensis(Bt)gene in rice will alter the relationship between transgene plants and weeds and induce undesirable environmental consequences are poorly understood.Thus,field experiments were conducted to investigate the weed competitiveness and assess the ecological risk of transgenic Bt rice under herbicide-free and lepidopterous pest-controlled environments.Results showed that weed–rice competition in the direct-sowing(DS)field was earlier and more severe than that in the transplanting(TP)field,which resulted in a significant decrease in biomass and yield in DS.However,conventional Bt and non-Bt rice yield was not significantly different.The weed number,weed coverage ratio,and weed diversity of conventional Bt rice were significantly higher than those of non-Bt rice at the early growth and mature stages,especially in DS plots,suggesting that Bt traits did not increase the weed competitiveness of transgenic rice and had no negative effect on weed diversity.Grain yield and weed number varied between different hybrid rice lines,but those differences were insignificant between Bt and non-Bt rice.The number of insects increased with the increase of weeds in hybrid rice plots,whereas the insect number and diversity did not display a significant difference between Bt and non-Bt rice.Therefore,the ecological risk of transgenic Bt rice is comparable to non-Bt rice.
基金the National Natural Science Foundation of China(NSFC)under Grant No.12171321.
文摘Gyllenberg and Yan(Discrete Contin Dyn Syst Ser B 11(2):347–352,2009)presented a system in Zeeman’s class 30 of 3-dimensional Lotka-Volterra(3D LV)competitive systems to admit at least two limit cycles,one of which is generated by the Hopf bifurcation and the other is obtained by the Poincaré-Bendixson theorem.Yu et al.(J Math Anal Appl 436:521–555,2016,Sect.3.4)recalculated the first Liapunov coefficient of Gyllenberg and Yan’s system to be positive,rather than negative as in Gyllenberg and Yan(2009),and pointed out that the Poincaré-Bendixson theorem is not applicable for that system.Jiang et al.(J Differ Equ 284:183–218,2021,p.213)proposed an open question:“whether Zeeman’s class 30 can be rigorously proved to admit at least two limit cycles by the Hopf theorem and the Poincaré-Bendixson theorem?”This paper provides four systems in Zeeman’s class 30 to admit at least two limit cycles by the Hopf theorem and the Poincaré-Bendixson theorem and gives an answer to the above question.
文摘After 5 years of accumulation, Animal Models and Experimental Medicine(AMEM) has received 396 manuscripts from 46 countries and regions, including Chinese mainland, Iran, the United States, India, Israel, Nigeria, Brazil, Bangladesh, Sri Lanka, the Netherlands, Denmark, Australia, Japan, and Spain. It has become an important international exchange and display platform for innovative research results in the field of laboratory animal science and basic medicine.
基金This work was supported in part by an International Research Partnership“Electrical Engineering-Thai French Research Center(EE-TFRC)”under the project framework of the Lorraine Universited’Excellence(LUE)in cooperation between Universitede Lorraine and King Mongkut’s University of Technology North Bangkok and in part by the National Research Council of Thailand(NRCT)under Senior Research Scholar Program under Grant No.N42A640328.
文摘With the daily expansion of global energy consumption,developing the power grids is of uttermost importance.However,building a new trans-mission line is costly and time-consuming,so utilizing the same lines with possible higher transmission capacity is very cost-effective.In this regard,to increase the capacity of the transmission lines,the flexible alternating current transmission system(FACTS)has been widely used in power grids in recent years by industrialized countries.One of the essential topics in electrical power systems is the reactive power compensation,and the FACTS plays a significant role in controlling the reactive power current in the power grid and the system voltage oscillations and stability.When a static synchronous compensator(STATCOM)is embedded in a power system to increase the bus voltage,a supplementary damping controller can be designed to enhance the system oscillation damping.Given the expansion of the grids in the power system,the complexity of their optimization and the extraordinary ability of the imperialist competitive algorithm(ICA)for solving such problems,in this paper,the ICA has been used to determine the optimal position and size of the FACTS devices.
基金supported by the National Natural Science Foundation of China under Grant Nos.62076225 and 62122093the Open Project of Xiangjiang Laboratory under Grant No 22XJ02003.
文摘This work aims to resolve the distributed heterogeneous permutation flow shop scheduling problem(DHPFSP)with minimizing makespan and total energy consumption(TEC).To solve this NP-hard problem,this work proposed a competitive and cooperative-based strength Pareto evolutionary algorithm(CCSPEA)which contains the following features:1)An initialization based on three heuristic rules is developed to generate a population with great diversity and convergence.2)A comprehensive metric combining convergence and diversity metrics is used to better represent the heuristic information of a solution.3)A competitive selection is designed which divides the population into a winner and a loser swarms based on the comprehensive metric.4)A cooperative evolutionary schema is proposed for winner and loser swarms to accelerate the convergence of global search.5)Five local search strategies based on problem knowledge are designed to improve convergence.6)Aproblem-based energy-saving strategy is presented to reduce TEC.Finally,to evaluate the performance of CCSPEA,it is compared to four state-of-art and run on 22 instances based on the Taillard benchmark.The numerical experiment results demonstrate that 1)the proposed comprehensive metric can efficiently represent the heuristic information of each solution to help the later step divide the population.2)The global search based on the competitive and cooperative schema can accelerate loser solutions convergence and further improve the winner’s exploration.3)The problembased initialization,local search,and energy-saving strategies can efficiently reduce the makespan and TEC.4)The proposed CCSPEA is superior to the state-of-art for solving DHPFSP.
文摘The climate issue has become an environmental concern for all sectors of the world and the low-carbon economy has thus become a new economic development model to combat climate change.With the development of low-carbon economy era,the textile and clothing industry plays an important role in stabilizing the development of low-carbon economy and society,and China has put forward the development requirements of low-carbon transformation for the textile and clothing industry,and also it has an important strategic value to promote the high-quality development of low-carbon economy and society,and the construction of brands’ core competitiveness is an inevitable choice for clothing brands in the face of the new form of international competition.As a result,the evaluation indicator of clothing brands’ core competitiveness in the low-carbon economy is used to measure the core competitiveness of clothing brands.Based on the corresponding verification results obtained by analytic hierarchy process(AHP) analysis,it can guide the low-carbon development of the clothing industry,thus proposing a more reasonable way to build the core competitiveness of clothing brands.It can promote the low-carbon transformation and upgrading of the clothing industry,effectively increase the market share of clothing brands,and promote the high-quality development of clothing brands.
基金supported by the Humanities and Social Sciences Fund for Yunnan Provincial Academy and School Education Cooperation(Grant No.SYSX202107)Scientific Research Fund of Yunnan Provincial Department of Education(Grant No.2022Y630)Science and Technology Innovation Fund of Southwest Forestry University(Grant No.KZ21006)。
文摘Due to the late start of China’s forest health industry,related research is lagging behind,which results in the inability to propose a corresponding path to enhance competitiveness.Based on this,the evaluation index system of provincial forest health industry competitiveness was constructed by using the Porter diamond model,and the Entropy-TOPSIS model is used to evaluate the competitiveness of China’s provincial forest health industry,and the key influencing factors of the forest health industry competitiveness are identified by using the grey correlation analysis method,and the specific promotion path was designed.The empirical results show that the grey correlation degree between related and supporting industries and the competitiveness score of the forest health industry is the highest,which confirms that it is the key influencing factor of the competitiveness of the forest health industry.Therefore,government departments should vigorously promote the integration of cultural tourism,medical care,pension and other related industries with the forest health care industry;enterprises should strengthen the construction of forest health infrastr ucture and supporting facilities to improve the level of forest health services.
文摘From the perspective of wellbeing performance of ecological input,this paper constructs a low-carbon competitiveness evaluation model with wellbeing performance of carbon emissions as the measurement standard,and uses the LMDI factor decomposition method to decompose the total effect of low-carbon competitiveness changes into technology effect and service effect.And then it conducts positive analysis and comparison of the low-carbon competitiveness and its effect contribution of G20 countries from1990 to 2018.The results are as follows:Firstly,in 2018,the UK,France,Argentina,Brazil,and Germany had higher low-carbon competitiveness.From 1990 to 2018,the low-carbon competitiveness of the UK,Turkey,Germany,Italy,and Brazil increase rapidly.Secondly,from 1990 to 2018,the total effect of low-carbon competitiveness of G20 member states was all positive,that is to say,the overall wellbeing performance of carbon emissions increased,technology effect and service effect are positive in 17 countries and negative in 2 countries respectively.Thirdly,China's low-carbon competitiveness is low,lacking static and dynamic advantages,although the technology effect is the highest,but the service effect is the lowest,resulting in a low total effect,which indicates that the wellbeing performance of economic growth is the main bottleneck of China's low-carbon development.Finally,the policy recommendations for China's future low-carbon transition and sustainable development are put forward.
文摘A mong the eight major steps China announced at the Third Belt and Road Forum for International Cooperation to support high-quality Belt and Road cooperation,the cancelation of all restrictions on foreign investment access in the manufacturing sector is the most striking measure,or at least one of the most eye-catching.
文摘With the economic globalization and the increasingly fierce industrial competition at home and abroad, the importance of industrial competitive intelligence service is becoming increasingly prominent. Under the policy background of cooperation and sharing, pluralistic coordination has become a new trend in regional economic development. The multi collaborative online service platform of industrial competitive intelligence is jointly constructed by all service subjects. The platform is guided and promoted by the government. Colleges and universities provide support for industrial competitive intelligence theory and professionals, scientific research institutes provide talent and advanced technology support, industry associations are responsible for dynamic monitoring of industrial development, and profit-making institutions are responsible for supplementing industrial competitive intelligence achievements. All service subjects integrate and explore existing intelligence resources and services through the unified online industrial competitive intelligence sharing platform, so as to realize benign cooperation, collaborative management, resource integration, user integration and service integration among subjects, so as to realize multiple collaborative services of industrial competitive intelligence.
基金Project name:Evolution of Growth Model and Cultivation of Competitive Advantage under Ambidextrous Innovation Strategy-A case study of China’s high-tech enterprises Project no.:JKY106320,Project category:National key project of the“14th Five-Year Plan”of Education and Scientific Research of the Ministry of Education The organization of the project chair:University of Malaya。
文摘This study focuses on the evolution of growth model and cultivation of competitive advantages under the ambidextrous innovation strategy.After a brief introduction of the connotation of ambidextrous innovation strategy,the evolution of growth model of high-tech enterprises under the conventional strategy and the ambidextrous innovation strategy is analyzed.Furthermore,a discussion is made on how to cultivate enterprises’competitive advantages under the ambidextrous innovation strategy,thereby enabling enterprises to stand out from competitors under this new strategic model and truly achieve the goal of sustainable development.
文摘This paper constructs a multiple collaborative service model of industrial competition intelligence with the main purpose of promoting the development of regional industries. The multiple service subjects include enterprises, governments, colleges and universities, scientific research institutes, industry associations and for-profit institutions. This article starts from the overall development of regional industrial economy, weighs the mutual relationship between the elements of the service model, and promotes multiple service subjects such as enterprises, governments, universities, research institutes, industry associations, and profit-making organizations to realize the collaborative service of resource intelligence, demand intelligence and data intelligence provides linkage intelligence service for the development and innovation of regional industries. This service model can improve the efficiency of industrial competitive intelligence services and the overall competitiveness of regional industries.
文摘Objective To analyze the current situation of medicine circulation enterprises and summarize the influence of frequently introduced industry policies on the pharmaceutical field,so as to provide suggestions on improving the competitiveness and maintaining sustainable development of medicine circulation enterprises in China.Methods Industry policy analysis,literature inquiry,expert interview and questionnaire survey were used to study the challenges that medicine circulation faced under the new situation.Then,the key indexes were found out to improve its competitiveness.Results and Conclusion Through the analysis of the current situation of the industry,policy orientation and market demand,some suggestions are put forward for related enterprises to improve their competitiveness.
