A novel route for dinitrification of N-phenylbenzenesulfonamide to synthesize N-(2,4-dinitrophenyl)benzenesulfonamide has been developed.The method features convenient operation and good functional group tolerance.Thi...A novel route for dinitrification of N-phenylbenzenesulfonamide to synthesize N-(2,4-dinitrophenyl)benzenesulfonamide has been developed.The method features convenient operation and good functional group tolerance.This reaction may go through a nitrogen dioxide radical(NO_(2)·)intermediate,which is generated by the thermal reaction process of sodium nitrate and ammonium persulfate.In addition,it provides direct approach for the preparation of 2,4-dinitroaniline derivatives which are crucial intermediate for the synthesis of benzimidazoles and quinoxaline derivatives.展开更多
文摘A novel route for dinitrification of N-phenylbenzenesulfonamide to synthesize N-(2,4-dinitrophenyl)benzenesulfonamide has been developed.The method features convenient operation and good functional group tolerance.This reaction may go through a nitrogen dioxide radical(NO_(2)·)intermediate,which is generated by the thermal reaction process of sodium nitrate and ammonium persulfate.In addition,it provides direct approach for the preparation of 2,4-dinitroaniline derivatives which are crucial intermediate for the synthesis of benzimidazoles and quinoxaline derivatives.
