期刊文献+
共找到304篇文章
< 1 2 16 >
每页显示 20 50 100
Discoid meniscus:Treatment considerations and updates
1
作者 Waleed Albishi Amjad Albaroudi +3 位作者 Abdulrahman M Alaseem Sarah Aljasser Ibrahim Alshaygy Abdullah Addar 《World Journal of Orthopedics》 2024年第6期520-528,共9页
A discoid meniscus is a morphological abnormality wherein the meniscus loses its normal‘C’shape.Although most patients are asymptomatic,patients might still present with symptoms such as locking,pain,swelling,or giv... A discoid meniscus is a morphological abnormality wherein the meniscus loses its normal‘C’shape.Although most patients are asymptomatic,patients might still present with symptoms such as locking,pain,swelling,or giving way.Magnetic resonance imaging is usually needed for confirmation of diagnosis.Based on a constellation of factors,including clinical and radiological,different approaches are chosen for the management of discoid meniscus.The purpose of this review is to outline the treatment of discoid meniscus,starting from conservative approach,to the different surgical options for this condition.The PubMed and Google Scholar databases were used for this review.Studies discussing the treatment of discoid meniscus from 2018 to 2023 were searched.Initially there were 369 studies retrieved,and after removal of studies using the exclusion criteria,26 studies were included in this review.Factors such as stability,presence of tear,and morphology can help with surgical planning.Many approaches have been used to treat discoid meniscus,where the choice is tailored for each patient individually.Postoperatively,factors that may positively impact patient outcomes include male sex,body mass index<18.5,age at symptom onset<25 years,and duration of symptoms<24 months.The conventional approach is partial meniscectomy with or without repair;however,recently,there has been an increased emphasis on discoid-preserving techniques such as meniscoplasty,meniscopexy,and meniscal allograft transplantation. 展开更多
关键词 discoid meniscus Saucerization Partial meniscectomy Meniscoplasty Meniscopexy Meniscal allograft transplantation ARTHROSCOPY KNEE
下载PDF
Specific Lethal Effects of Trace Neutral Red on Amoeba discoides and Trichodina 被引量:1
2
作者 XIANG Xlan-yuan WU Shao-fang WANG An-tai 《Animal Husbandry and Feed Science》 CAS 2009年第11期29-32,36,共5页
[ Objective] The aim of this study was to provide the reference for the artificial breeding of aquatic animals. [ Method] Amoeba discoides and Trichodina were treated by neutral red solution with different concentrati... [ Objective] The aim of this study was to provide the reference for the artificial breeding of aquatic animals. [ Method] Amoeba discoides and Trichodina were treated by neutral red solution with different concentrations to observe the physiological activities of organelles in their death processes. Effects of neutral red solution on the growth of common aquatic animals such as Paramecium caudatum, Euglena viridis and Brachionus plicatilis were analyzed, and the specific lethal mechanism of trace neutral red to A. discoides and Trichodina was also preliminarily studied. [ Re- suit] The neutral red solution at a concentration of 0.5 mg/L damaged the physiological function of contractile vacuole in Trichodina and also had the specific lethal effect on Tdchodina, but it had no effect on the growth and reproduction of non-parasitic protozoa and B. p/icatilis. Neutral red so- lution with certain concentration led to disorder of the physiological functions of A. discoides, such as assimilation and rejection, which was a main factor that caused the death of A. discoides. [ Conclusion] With the advantages such as targeting, safety and easiness to be oxidized and decom- posed, neutral red is an ideal drug for treating the diseases caused by A. discoides and Trichodina, and its suitable concentration is 0. 5 mg/L. 展开更多
关键词 Neutral red Amoeba discoides Trichodina Specific lethal effect
下载PDF
Discoid medial meniscus of both knees:A case report
3
作者 Zhong-Ren Zheng Hui Ma +4 位作者 Fei Yang Long Yuan Guo-Dong Wang Xiao-Wei Zhao Long-Fei Ma 《World Journal of Clinical Cases》 SCIE 2022年第25期9020-9027,共8页
BACKGROUND Discoid meniscus is a congenital anomaly that typically affects the lateral meniscus.The appearance of the discoid medial meniscus in both knees is extremely rare,with an incidence of only 0.012%.CASE SUMMA... BACKGROUND Discoid meniscus is a congenital anomaly that typically affects the lateral meniscus.The appearance of the discoid medial meniscus in both knees is extremely rare,with an incidence of only 0.012%.CASE SUMMARY Our patient was a 30-year-old female.Under no obvious predisposing causes,she began to experience pain in both knees,which worsened while walking and squatting.The pain was aggravated after exercise,and joint flexion and extension activities were accompanied by knee snapping.Apley’s test was positive on physical examination,and there was a pressing pain in the medial articular space.Plain radiographs of both knees revealed no obvious abnormalities in the bilateral knee joint space.Partial meniscectomy as well as menisci reformation were performed on both knees under arthroscopy.Under the guidance of rehabilitation,the patient’s range of motion in both knees returned to normal without pain and knee snapping.CONCLUSION This study showed that the clinical manifestations of the discoid medial meniscus injury are identical to those of the conventional medial meniscus injury,and arthroscopic surgery is effective. 展开更多
关键词 Medial discoid meniscus ARTHROSCOPY Knee joint Menisci reformation Magnetic resonance imaging Case report
下载PDF
ARTHROSCOPIC TREATMENT FOR DISCOID LATERAL MENISCUS INJURY OF THE KNEE IN CHILDREN
4
作者 蒋垚 赵金忠 +1 位作者 翟伟韬 曾炳芳 《Journal of Shanghai Second Medical University(Foreign Language Edition)》 2001年第1期41-45,共5页
Objective To study the arthroscopic treatment results for discoid lateral meniscus injury of the knee in children. Methods 74 children patients, including 98 knees underwent arthroscopic treatment due to discoid later... Objective To study the arthroscopic treatment results for discoid lateral meniscus injury of the knee in children. Methods 74 children patients, including 98 knees underwent arthroscopic treatment due to discoid lateral meniscus injury were followed up. By Watanabe classification, incomplete discoid menis-cus was seen in 34 knees, complete in 42 and Wrisberg type in 22. The methods of treatment were partial, subtotal or total meniscectomy. The follow-up time ranged from 3 to 24 months, averaged 8 months. The re-sults were analyzed according to Lysholm knee evaluation method. Results By Lysholm evaluation the re-sults were excellent in 68 knees (69. 4%) and good in 30 (30. 6%). Conclusion Arthroscopic treatment is a reliable way for discoid lateral meniscus injury in children. 展开更多
关键词 arthroscopy discoid meniscus children
下载PDF
基于MRI完全型盘状半月板矢状位的形态分析
5
作者 戴祝 陈宇浠 +4 位作者 邬赫 廖瑛 吴彪 黄文 明誉 《实用骨科杂志》 2024年第7期617-620,共4页
目的基于MRI观察完全型外侧盘状半月板(complete discoid lateral meniscus,CDLM)与正常外侧半月板矢状位的形态学差异,探索CDLM破裂的机制。方法收集2017年1月至2020年12月于南华大学附属第一医院行膝关节镜半月板手术的患者资料,选取... 目的基于MRI观察完全型外侧盘状半月板(complete discoid lateral meniscus,CDLM)与正常外侧半月板矢状位的形态学差异,探索CDLM破裂的机制。方法收集2017年1月至2020年12月于南华大学附属第一医院行膝关节镜半月板手术的患者资料,选取符合纳入标准的95例99膝,其中男36例38膝,女59例61膝;年龄18~55岁,平均(45.63±6.81)岁。其中29例30膝CDLM破裂(A组),16例16膝CDLM未破裂(B组),51例53膝正常外侧半月板(C组)。分别测量半月板前后径(anteroposterior diameter,APD)以及外侧胫骨近端前后径(tibial diameter,TD),用组内相关系数(intraclass correlation coefficient,ICC)分析测量者之间的一致性,取两次测量的平均值,计算APD/TD比值,比较各组之间的差异。结果APD和TD测量的ICC值分别为0.782和0.972。A组和B组APD比较差异无统计学意义(P>0.05),但两组均小于C组(P<0.05)。A组和B组TD比较差异无统计学意义(P>0.05),但A组明显小于C组(P<0.05)。A组APD/TD比值大于B组(P<0.05),但与C组比较差异无统计学意义(P>0.05),B组APD/TD比值小于C组(P<0.05)。结论CDLM的APD及TD均较正常半月板小,CDLM破裂后APD增大。 展开更多
关键词 外侧盘状半月板 核磁共振 矢状位
下载PDF
Torn discoid lateral meniscus treated with arthroscopic meniscectomy:observations in 62 knees 被引量:11
6
作者 LU Ying LI Qiang HAO Jie 《Chinese Medical Journal》 SCIE CAS CSCD 2007年第3期211-215,共5页
Background Discoid lateral meniscus of the knee is common in Chinese population. There has been considerable debate about the best treatment for discoid lateral meniscus tears. The purpose of this study was to observe... Background Discoid lateral meniscus of the knee is common in Chinese population. There has been considerable debate about the best treatment for discoid lateral meniscus tears. The purpose of this study was to observe the effect of arthroscopic meniscectomy for the treatment of discoid lateral meniscus tears. Methods Between July 1999 and December 2004, arthroscopic meniscectomy was performed on 62 menisci of 57 patients with discoid lateral meniscus tears (52 unilateral, 5 bilateral). 41 menisci were "complete discoid meniscus", 21 =incomplete". According to the extent of the meniscus tears, partial meniscectomy was performed on 52 knees, total meniscectomy on 7 knees, and partial meniscectomy combined with meniscus suture on 3 knees through an arthroscope After the operations, early rehabilitation training programs, including straight-leg-raising and range-of-motion exercises, were carried out. 51 patients were followed up for 1 year 2 months to 6 years 5 months (mean, 3 years 3 months), 6 patients were lost. Lysholm-Ⅱ scoring system was used to assess the function of the knee joints before the operation and during the follow-up. Results The operations on all the 62 knees were successful without complications. The patients could walk normally after completing the 2-week postoperation rehabilitation program. After 3-4 weeks they could lead a normal life and participate in a moderate amount of sports or other physical activities. The mean Lysholm-Ⅱ score was 89 (60--100) during the follow-up, which was significantly higher than that before the operation (50, range 34-74; P〈0.01). 88% of the patients achieved excellent or good clinical results. Conclusions Arthroscopic meniscectomy is an alternative for treatment of discoid lateral meniscus tears with minimal traumatic effects. It can achieve early mobilization and a low complication rate, as well as the preservation of the meniscus structure and functions to the largest extent. In combination with proper rehabilitation training, the operation can lead to good or excellent results. 展开更多
关键词 knee joint discoid meniscus tear ARTHROSCOPY MENISCECTOMY
原文传递
关节镜下外侧盘状半月板部分切除术结合下肢力线对齐治疗外侧盘状半月板患者的临床效果
7
作者 李勇 尹战海 +5 位作者 边卫国 张军武 李宏伟 高智 贺加明 高磊 《临床医学研究与实践》 2024年第8期39-42,共4页
目的探讨关节镜下外侧盘状半月板部分切除术结合下肢力线对齐治疗外侧盘状半月板患者的临床效果。方法根据1∶1随机数字表法将102例外侧盘状半月板患者分为对照组和研究组,各51例。对照组给予单纯关节镜下外侧盘状半月板部分切除术治疗... 目的探讨关节镜下外侧盘状半月板部分切除术结合下肢力线对齐治疗外侧盘状半月板患者的临床效果。方法根据1∶1随机数字表法将102例外侧盘状半月板患者分为对照组和研究组,各51例。对照组给予单纯关节镜下外侧盘状半月板部分切除术治疗,研究组给予关节镜下外侧盘状半月板部分切除术结合下肢力线对齐治疗。比较两组的治疗效果。结果术后1个月、1年,研究组的下肢力线短于对照组,Lysholm、国际膝关节评分委员会(IKDC)评分高于对照组(P<0.05)。两组的术后住院时间无显著差异(P=0.074)。研究组的并发症总发生率低于对照组(P<0.05)。结论关节镜下外侧盘状半月板部分切除术结合下肢力线对齐治疗外侧盘状半月板患者的效果良好。 展开更多
关键词 外侧盘状半月板 关节镜 下肢力线对齐
下载PDF
儿童盘状半月板损伤手术预后的影响因素和并发症研究进展
8
作者 张海锐 赵志尧 +1 位作者 黄炳哲 刘晓宁 《中国骨伤》 CAS CSCD 2024年第1期98-102,共5页
盘状半月板是一种常见的先天性的半月板畸形,主要在亚洲人中多见,常累及外侧半月板。对于无症状的盘状半月板患者通常采取观察、避免受伤等保守方法治疗,对于有症状和撕裂的患者则需要行手术方法治疗。目前多采取关节镜下半月板成形术... 盘状半月板是一种常见的先天性的半月板畸形,主要在亚洲人中多见,常累及外侧半月板。对于无症状的盘状半月板患者通常采取观察、避免受伤等保守方法治疗,对于有症状和撕裂的患者则需要行手术方法治疗。目前多采取关节镜下半月板成形术联合半月板部分切除术和半月板修复术,并且早期至中期的报告良好。患者的手术年龄、术后随访时间和手术类型都是预后的影响因素。部分患者手术后会出现膝关节长时间疼痛,早期骨关节炎,再撕裂和剥脱性软骨炎等并发症。其中长时间疼痛的发生率较高,剥脱性软骨炎的发生率最低。半月板再撕裂则是患者行二次手术的主要原因。 展开更多
关键词 盘状半月板 手术结果 术后并发症 儿童 综述文献
下载PDF
Lessons Learned from a Case with Valgus Deformity of the Knee Following Partial Removal of Lateral Discoid Meniscus 被引量:3
9
作者 Ming Li Hua Liu +3 位作者 Zhi-Yong He Zheng-Lin Di Jun-Hui Zhang Qun-Hua Jin 《Chinese Medical Journal》 SCIE CAS CSCD 2015年第21期2967-2968,共2页
Few studies have focused on the possible change in the axial alignment of the lower limb after lateral meniscectomy. Here, we present a patient with valgus deformity of the knee following the partial removal of latera... Few studies have focused on the possible change in the axial alignment of the lower limb after lateral meniscectomy. Here, we present a patient with valgus deformity of the knee following the partial removal of lateral discoid meniscus. With the distal femur osteotomy and fixation, this complication was treated successfully. This case suggested that we should pay more attention to the axial alignment of the lower limb in patients with torn discoid lateral meniscus before meniscectomy, as a severe valgus inclination may develop in some of these patients. 展开更多
关键词 Distal Femur Osteotomy Lateral discoid Meniscus MENISCECTOMY Valgus Deformity
原文传递
外侧盘状半月板的中西医治疗新进展
10
作者 林峰 车广伟 +1 位作者 余明琅 黄勇 《实用医院临床杂志》 2024年第3期26-29,共4页
盘状半月板作为半月板的一种先天变异,由Young在1889年首次提出,属中医学“伤筋”范畴。该病的形成机制尚不明确,多存在于外侧半月板,损伤多与活动相关,且在亚洲人群多发。临床上多建议以手术治疗为主,而随着中医治疗的不断研究,也为我... 盘状半月板作为半月板的一种先天变异,由Young在1889年首次提出,属中医学“伤筋”范畴。该病的形成机制尚不明确,多存在于外侧半月板,损伤多与活动相关,且在亚洲人群多发。临床上多建议以手术治疗为主,而随着中医治疗的不断研究,也为我们临床治疗提供了多种方案。本文对当前外侧盘状半月板的中西医治疗情况进行综述,以期为临床工作提供一定的指导作用。 展开更多
关键词 外侧盘状半月板 中西医结合 治疗
下载PDF
关节镜下不同缝合法在膝关节外侧盘状半月板损伤患者治疗中的对比观察
11
作者 占鹏 陈东风 李瑛 《中外医学研究》 2024年第30期46-49,共4页
目的:观察比较关节镜下采用不同缝合法治疗膝关节外侧盘状半月板损伤的临床效果。方法:选取2020年6月—2023年6月龙岩市第一医院治疗的84例膝关节外侧盘状半月板损伤接受关节镜手术治疗患者作为研究对象,采用方便抽样法随机分为全内组... 目的:观察比较关节镜下采用不同缝合法治疗膝关节外侧盘状半月板损伤的临床效果。方法:选取2020年6月—2023年6月龙岩市第一医院治疗的84例膝关节外侧盘状半月板损伤接受关节镜手术治疗患者作为研究对象,采用方便抽样法随机分为全内组和内外组。每组各42例。全内组术中采取全内缝合法,内外组术中采取内外缝合法。观察并比较两组患者的手术情况、术后体征情况、视觉模拟量表(VAS)评分、Lysholm评分及术后并发症情况。结果:全内组术中出血量、手术时间、术后住院时间均显著低于内外组,差异有统计学意义(P<0.05);关节间隙压痛、关节绞索、Mc Murray征阳性率均显著低于内外组,差异有统计学意义(P<0.05);术后1个月、3个月,两组关节VAS评分比术前显著降低,Lysholm评分比术前显著升高,且全内组显著优于内外组,差异有统计学意义(P<0.05);两组均无术后并发症,仅内外组在术后3个月出现膝关节屈伸活动伴有不适、膝关节过紧情况,发生率显著高于全内组,差异有统计学意义(P<0.05)。结论:膝关节外侧盘状半月板损伤患者关节镜术中采取全内缝合法相较于内外缝合法可以有效缩短手术时间,降低术中出血量,减轻关节疼痛,避免神经、血管损伤从而促进膝关节功能恢复,避免术后出现膝关节屈伸活动不适、关节过紧情况。 展开更多
关键词 关节镜手术 全内缝合法 内外缝合法 盘状半月板损伤 膝关节功能
下载PDF
Bilateral complete type discoid medial menisci: an adult patient with tears in both knees 被引量:2
12
作者 LU Ying LIU Feng-qi MENG Hai 《Chinese Medical Journal》 SCIE CAS CSCD 2013年第13期2587-2588,共2页
Adiscoid meniscus, found in 1%-5% of the population, .is a human anatomic variant that usually affects thelateral meniscus of the knee. A discoid meniscus is more prone to injury than a normally shaped meniscus. In 19... Adiscoid meniscus, found in 1%-5% of the population, .is a human anatomic variant that usually affects thelateral meniscus of the knee. A discoid meniscus is more prone to injury than a normally shaped meniscus. In 1941,1 Cave and Staples first reported discoid medial meniscus. A bilateral discoid medial meniscus is extremely rare. The first case of bilateral discoid medial meniscus was reported by Murdoch in 1956.2 Since then, no more than 20 case reports of bilateral discoid medial menisci have been published to date, and most have been single case reports.3 Treatment of a torn discoid medial meniscus is similar to the treatment of a tom lateral meniscus of the knee. In cases where there is a significant disability, surgical excision may be required. Traditionally, the treatment of choice for symptomatic torn discoid meniscus has been open total or partial meniscectomy. Currently, arthroscopic partial meniscectomy is commonly used. Either meniscectomy or conservative method for treatment of a discoid medial meniscus with no tear is a debatable issue.3 A 39-year-old male was admitted to our hospital for intermittent swelling and pain of his right knee in 1999. He had a history of twisting injury on the affected knee 10 years before the admission, but the symptoms were not significant at that time. However, one year ago, on and off swelling with pain had gradually developed in his right knee, worsening with long distance walking and sports activities. Sometimes he felt that the knee was "giving way". Due to increasing discomfort interfering with his daily life, he was referred to us by his doctor. Physical examination of the patient's right knee showed atrophy of the musculus quadriceps femoris compared to the opposite side, medial tibiofemoral joint line tenderness, a range of motion from , and positive McMurray sign. The patient had no complaints on his opposite knee and physical examination did not reveal any abnormalities. MRI scan showed discoid medial meniscus with a horizontal cleavage tear while lateral meniscus appeared normal (Figure IA, B). On 16th August 1999, arthroscopic examination of the right knee confirmed the presence of a complete discoid medial meniscus with horizontal cleavage and longitudinal tears and a normal lateral meniscus, while the tom discoid medial meniscus was reshaped by arthrotomy partial meniscectomy. The patient has been followed up for12 years, and the treatment outcome has been good and satisfactory to date. In 2011, the same patient was admitted again for intermittent swelling, pain and locking of his left knee. The patient experienced symptoms for 6 months with no previous history of injury. Physical examination of the left knee showed effusion of (++) in the joint, atrophy of the musculus quadriceps femoris, medial tibiofemoral joint line tenderness, restriction of mobility, range of motion , and positive McMurray sign. MRI showed discoid medial meniscus with a horizontal cleavage in mid-body and posterior horn while the lateral meniscus appeared normal (Figure 1C, D). Arthroscopic surgery was performed on 20th July 2011. Upon arthroscopic observation, discoid medial meniscus in the left knee was found to be the complete type with a horizontal cleavage in mid-body and longitudinal tears near the peripheral rim, but the lateral meniscus was normal. Discoid medial meniscus was reshaped by partial meniscectomy, using arthroscopic techniques (Figure 1E, F). Discoid meniscus is found in 1%-5% of the population, with a slightly higher incidence in Asians. Discoid meniscus is an uncommon finding that typically affects the lateral meniscus of the knee, and the involvement of the medial meniscus bilaterally is extremely rare. A retrospective study was conducted by Dickason and colleagues in 1982,4 in which 8040 cases of medial menisci were analyzed. Among them, 10 were discoid menisci (0.12%), and only one had bilateral involvement (0.012%). Several studies on findings of bilateral discoid medial menisci have been reported by Asian doctors in recent years.3 To date, as few as 20 cases of bilateral discoid medial menisci have been reported. Interestingly, in the present case, the symptoms of the two knees appeared 12 years apart. We have confirmed the diagnosis of complete discoid medial menisci with tearing in the right knee in 1999 and the left knee in 2011. 展开更多
关键词 bilateral discoid medial meniscimeniscectomy magnetic resonance imaging arthroscopy
原文传递
关节镜修复术联合自体富血小板血浆注射治疗盘状半月板伴撕裂的临床疗效
13
作者 杨芳 刘数敬 +1 位作者 华伟伟 王波 《中国现代手术学杂志》 2024年第1期58-64,共7页
目的 研究关节镜下盘状半月板修复术联合自体富血小板血浆(plate rich plasm, PRP)注射治疗盘状半月板伴撕裂的临床疗效。方法 2020年6月至2022年12月共收治因盘状半月板伴撕裂就诊的患者26例,均为男性,平均年龄21.6(19~25)岁。研究组1... 目的 研究关节镜下盘状半月板修复术联合自体富血小板血浆(plate rich plasm, PRP)注射治疗盘状半月板伴撕裂的临床疗效。方法 2020年6月至2022年12月共收治因盘状半月板伴撕裂就诊的患者26例,均为男性,平均年龄21.6(19~25)岁。研究组13例采取关节镜下半月板修复术联合PRP注射治疗,对照组13例单纯采用关节镜下半月板修复术,在术前、术后3个月、6个月及1年分别评估患者的疼痛视觉模拟评分(visual analogue scale, VAS)、国际膝关节评分委员会(International Knee Documentation Committee, IKDC)评分及膝关节活动度。结果 所有患者均取得了良好的治疗效果,随访过程中未发生不良事件。术后3个月研究组的VAS明显低于对照组(P<0.05),但术后6个月、12个月两组无统计学差异(P>0.05);研究组术后各个阶段IKDC评分均优于对照组(P<0.05);而术后膝关节活动度与对照组相比差异无统计学意义(P>0.05)。结论 关节镜下半月板修复术联合PRP注射治疗对盘状半月板伴撕裂患者疗效较好,能够缓解疼痛,改善膝关节功能,PRP能够促进半月板的愈合。 展开更多
关键词 盘状半月板 半月板损伤 关节镜 半月板修复术 富含血小板血浆
下载PDF
关节镜治疗青少年症状性盘状和非盘状半月板的临床疗效对比研究
14
作者 张海参 张峰 +2 位作者 庄泽民 郝健明 魏厚全 《现代医药卫生》 2024年第4期605-609,共5页
目的 对比分析在青少年患者中采用关节镜治疗症状性盘状半月板(DLM)和非DLM的膝关节功能和临床预后。方法 回顾性分析2015-2021年该院收治的47例关节镜治疗的青少年患者,根据是否为DLM分为DLM组(20例)和非DLM组(27例)。比较分析2组患者... 目的 对比分析在青少年患者中采用关节镜治疗症状性盘状半月板(DLM)和非DLM的膝关节功能和临床预后。方法 回顾性分析2015-2021年该院收治的47例关节镜治疗的青少年患者,根据是否为DLM分为DLM组(20例)和非DLM组(27例)。比较分析2组患者临床特征、手术类型,以及术后6个月,1、2年国际膝关节评分委员会(IKDC)、体力活动问卷(PAQ)评分的差异。结果 DLM组患者年龄、体重指数均较非DML组低,差异均有统计学意义(P<0.05)。2组患者术后6个月,1、2年IKDC、PAQ评分均较术前明显改善,差异均有统计学意义(P<0.05),但2组患者各时间点IKDC、PAQ评分比较,差异均无统计学意义(P>0.05)。不同性别、年龄、手术类型患者IKDC、PAQ评分比较,差异均无统计学意义(P>0.05)。结论 关节镜手术能有效改善DLM和非DLM组患者膝关节功能,而性别、手术类型、年龄均不会影响术后膝关节功能和体力恢复情况。 展开更多
关键词 关节镜 盘状半月板 青少年 治疗结果 对比研究
下载PDF
关节镜下成形缝合术治疗完全型盘状半月板损伤的效果分析
15
作者 陈艳 魏擎 《中国社区医师》 2024年第5期56-58,共3页
目的:分析关节镜下成形缝合术治疗完全型盘状半月板损伤的效果。方法:选取2017年1月—2022年12月北京丰台医院收治的完全型盘状半月板损伤患者96例作为研究对象,依据随机数字表法分为观察组和对照组,各48例。对照组实施关节镜下盘状半... 目的:分析关节镜下成形缝合术治疗完全型盘状半月板损伤的效果。方法:选取2017年1月—2022年12月北京丰台医院收治的完全型盘状半月板损伤患者96例作为研究对象,依据随机数字表法分为观察组和对照组,各48例。对照组实施关节镜下盘状半月板全切除术,观察组实施关节镜下盘状半月板成形缝合术。比较两组膝关节功能、并发症发生情况。结果:术前,两组下蹲、爬楼梯、肿胀、疼痛、不稳定、交锁、支撑、跛行评分及总分比较,差异无统计学意义(P>0.05);术后,两组下蹲、爬楼梯、肿胀、疼痛、不稳定、交锁、支撑、跛行评分及总分高于术前,且观察组高于对照组,差异有统计学意义(P<0.05)。术后3个月,观察组并发症发生率低于对照组,差异有统计学意义(P<0.001)。结论:关节镜下成形缝合术治疗完全型盘状半月板损伤的效果较好,可改善患者膝关节功能,降低并发症发生率。 展开更多
关键词 关节镜 成形缝合术 完全型盘状半月板损伤
下载PDF
酞菁类盘状液晶材料研究进展 被引量:1
16
作者 王桂霞 殷宇通 +3 位作者 王佳伟 张林峰 周超 孔翔飞 《精细化工》 EI CAS CSCD 北大核心 2023年第8期1645-1655,共11页
拥有大环π电子高度共轭结构的酞菁(Pc)核,具备自组装的潜在特征,且在可见光区域具有强吸收。经修饰改性的酞菁衍生物被应用于液晶显示、太阳能电池、非线性光学等光电材料中。其中,液晶相行为影响材料性能方面更引人关注。通过修饰酞... 拥有大环π电子高度共轭结构的酞菁(Pc)核,具备自组装的潜在特征,且在可见光区域具有强吸收。经修饰改性的酞菁衍生物被应用于液晶显示、太阳能电池、非线性光学等光电材料中。其中,液晶相行为影响材料性能方面更引人关注。通过修饰酞菁核可以改变液晶相行为,最具有代表性的修饰是酞菁核中心空腔阳离子配位和外围添加取代基团。经修饰改性的酞菁衍生物柱状自组装趋势明显,盘状中间相易形成,共轭层之间电子的传输能力得到增强,具备了作为光电材料的基本性质。该文综述了近十几年来酞菁衍生物盘状液晶材料的研究进展,总结了酞菁核的结构修饰对其液晶性能影响之间的构效关系,最后对酞菁衍生物盘状液晶在高性能材料合成方面存在的缺陷和研究方向进行了展望。 展开更多
关键词 酞菁核 酞菁衍生物 盘状液晶 修饰 构效关系
原文传递
膝关节盘状半月板损伤患者关节镜术后疼痛的列线图预测模型构建
17
作者 柴晟 蒋杰 +3 位作者 屈宗斌 邓章荣 吕青 曾伟清 《广东医学》 CAS 2023年第3期357-361,共5页
目的分析膝关节盘状半月板(DLM)损伤患者关节镜术后疼痛的危险因素,并构建列线图预测模型。方法收集2017年1月至2021年12月行关节镜手术治疗的217例DLM损伤患者临床资料。依照NRS数字分级法评估术侧膝关节及髌周疼痛情况,将患者分为疼痛... 目的分析膝关节盘状半月板(DLM)损伤患者关节镜术后疼痛的危险因素,并构建列线图预测模型。方法收集2017年1月至2021年12月行关节镜手术治疗的217例DLM损伤患者临床资料。依照NRS数字分级法评估术侧膝关节及髌周疼痛情况,将患者分为疼痛组(≤4分,n=26)和非疼痛组(≥4分,n=191)。采用受试者工作特征(ROC)曲线分析获取有统计学意义的连续性变量的最佳截断值。采用多因素logistic回归模型分析DLM损伤患者关节镜术后疼痛的危险因素。构建预测DLM损伤患者关节镜术后疼痛的列线图预测模型,采用校正曲线对列线图预测模型进行内部验证和性能评价,决策曲线对列线图预测模型的预测效能进行临床净收益评估。结果疼痛组患者年龄、关节软骨损伤比例、术后无冷敷比例均高于非疼痛组(P<0.05),术后负重时间早于非疼痛组(P<0.05)。ROC曲线分析显示:年龄、术后负重时间的AUC分别为0.767、0.774;最佳截断值分别为54岁、7 d。年龄(>54岁)、关节软骨损伤(有)、术后负重时间(≤7 d)是DLM损伤患者关节镜术后疼痛的独立危险因素,术后冷敷(有)是DLM损伤患者关节镜术后疼痛的保护因素。内部验证结果显示,列线图模型预测DLM损伤患者关节镜术后疼痛的C-index为0.758(95%CI:0.657~0.949)。校准曲线显示观测值与预测值之间保持较好一致性。列线图模型预测DLM损伤患者关节镜术后疼痛的阈值>0.12,列线图预测模型提供临床净收益;此外,列线图预测模型临床净收益均高于年龄、关节软骨损伤、术后负重时间、术后冷敷。结论本研究基于年龄、关节软骨损伤、术后负重时间、术后冷敷,构建了预测DLM损伤患者关节镜术后疼痛的列线图模型,该模型对于DLM损伤患者关节镜术后疼痛有较好的预测价值,可用于识别术后疼痛发生的高危患者。 展开更多
关键词 盘状半月板 损伤 关节镜 术后疼痛 列线图
下载PDF
DDR1对结直肠癌侵袭和上皮细胞间质转化的影响
18
作者 任清霞 田斌 +1 位作者 苏彤 孙良臣 《分子诊断与治疗杂志》 2023年第7期1182-1186,共5页
目的探究盘状结构域受体1(DDR1)对结直肠癌侵袭、上皮间质转化(EMT)的影响及机制。方法收集2018年1月至2021年1月在日照市人民医院进行外科手术肿瘤切除治疗的60例结直肠癌癌组织及其癌旁组织。免疫组化检测结直肠癌组织和癌旁组织中DDR... 目的探究盘状结构域受体1(DDR1)对结直肠癌侵袭、上皮间质转化(EMT)的影响及机制。方法收集2018年1月至2021年1月在日照市人民医院进行外科手术肿瘤切除治疗的60例结直肠癌癌组织及其癌旁组织。免疫组化检测结直肠癌组织和癌旁组织中DDR1蛋白表达水平。体外培养人结肠上皮细胞和结直肠癌细胞,Western blot检测DDR1蛋白表达水平。随后结直肠癌上皮细胞分为转染DDR1阴性干扰片段组(DDR1⁃NC)、转染DDR1干扰片段组(DDR1⁃siRNA)、过表达DDR1无关片段组(OVE⁃NC)和过表达DDR1组(OVE⁃DDR1),Western blot检测DDR1、IL⁃6、p⁃STAT3和EMT相关蛋白表达变化。Trasnswell检测结直肠癌细胞侵袭情况。结果与癌旁组织相比,结直肠癌组织DDR1蛋白阳性表达率明显增加,差异有统计学意义(χ^(2)=20.979,P<0.05)。与人结肠上皮细胞相比,结直肠癌细胞DDR1蛋白表达明显增加差异有统计学意义(t=2.970、8.398、4.977、5.253,P<0.05)。与DDR1⁃NC组相比,DDR1⁃siRNA组细胞DDR1、IL⁃6、p⁃STAT3蛋白表达降低,差异有统计学意义(t=3.533、4.021、3.864,P<0.05),结直肠癌细胞侵袭能力降低,差异有统计学意义(t=6.695,P<0.05)、EMT进程被抑制。与OVE⁃NC组相比,OVE⁃DDR1组细胞DDR1、IL⁃6、p⁃STAT3蛋白表达升高,差异有统计学意义(t=4.752、6.759、4.896,P<0.05),结直肠癌细胞侵袭能力增加,差异有统计学意义(t=4.181,P<0.05),促进EMT进程。结论DDR1在结直肠癌细胞中表达升高,其能够通过调控IL⁃6/STAT3信号促进结直肠癌细胞侵袭和EMT。 展开更多
关键词 结直肠癌 盘状结构域受体1 侵袭 上皮间质转化 IL⁃6/STAT3信号
下载PDF
内外双针缝合法与全内缝合法在关节镜手术治疗膝关节外侧盘状半月板损伤中的效果比较 被引量:6
19
作者 王尉霖 王超 +1 位作者 王雷弟 张大刚 《实用医院临床杂志》 2023年第3期47-50,共4页
目的探讨内外双针缝合法与全内缝合法在关节镜手术治疗膝关节外侧盘状半月板损伤中的效果。方法我院收治的153例膝关节外侧盘状半月板损伤患者,其中74例采用全内缝合法为研究组,79例采用内外双针缝合法为对照组。比较两组膝关节功能Lysh... 目的探讨内外双针缝合法与全内缝合法在关节镜手术治疗膝关节外侧盘状半月板损伤中的效果。方法我院收治的153例膝关节外侧盘状半月板损伤患者,其中74例采用全内缝合法为研究组,79例采用内外双针缝合法为对照组。比较两组膝关节功能Lysholm评分、AKS评分、VAS疼痛评分、手术时间、医疗费用、并发症。结果与术前比较,术后1、3、6个月两组Lysholm评分、AKS评分升高,VAS评分降低,且研究组的Lysholm评分、AKS评分高于对照组,VAS评分低于对照组(P<0.05)。与对照组比较,研究组手术时间更短,医疗费用更高,并发症发生率更低(P<0.05)。结论相比内外双针缝合法,全内缝合法操作更加简单,膝关节功能恢复更好。 展开更多
关键词 膝关节 盘状半月板 关节镜手术 内外双针缝合法 全内缝合法
下载PDF
全外显子测序盘状半月板的病因学分析 被引量:2
20
作者 张键 林坚平 +2 位作者 周钢 王本超 吴永昌 《中国组织工程研究》 CAS 北大核心 2023年第2期192-199,共8页
背景:盘状半月板是一种半月板形态学改变,至今发病机制不明,目前尚无关于盘状半月板的基因组学研究。目的:通过外显子测序结合生物信息学分析筛选盘状半月板可疑致病基因。方法:提取7例盘状半月板患者的外周血DNA,分别建库后进行全外显... 背景:盘状半月板是一种半月板形态学改变,至今发病机制不明,目前尚无关于盘状半月板的基因组学研究。目的:通过外显子测序结合生物信息学分析筛选盘状半月板可疑致病基因。方法:提取7例盘状半月板患者的外周血DNA,分别建库后进行全外显子测序,测序数据与公共基因组数据库对比筛选变异位点,并进行可疑致病突变注释及解读。结果与结论:①7例患者共筛选出变异位点6943个,其中错义突变3620个,同义突变732个,剪接位点附近的突变488个,剪接位点突变45个,外显子重复20个,外显子缺失84个,非移码突变136个,截断突变54个,延长突变5个,起始位点突变8个;②基于共有突变基因和公共基因数据库筛选出可疑致病基因6个,分别为PADI4、FLNB、SYNE1、COL11A2、COL2A1、MYO9A,包含变异位点15个,结合突变频率数据库、蛋白危害性分析结果和国内外相关研究确定盘状半月板可疑基因为PADI4、FLNB、SYNE1、COL11A2、COL2A1。 展开更多
关键词 盘状半月板 全外显子测序 病因学 发病机制 基因组学
下载PDF
上一页 1 2 16 下一页 到第
使用帮助 返回顶部