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Research on Cyber-Physical Modeling for Smart Distribution Grid
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作者 Xiaohong Guo Shuyi Guo +1 位作者 Gang Li Yu Song 《Energy and Power Engineering》 2017年第4期544-551,共8页
Smart distribution network will achieve the optimal operation of the distribution network, provide high-quality and reliable power, guarantee the development of modern social economy. The deep integration of cyber sys... Smart distribution network will achieve the optimal operation of the distribution network, provide high-quality and reliable power, guarantee the development of modern social economy. The deep integration of cyber system and power physical system is the key to smart distribution network. The emergence of cyber-physical system (CPS) provides a new way to solve this problem, the cyber-physical model for smart distribution grid becomes an urgent problem to be solved. In this paper, the content and method of cyber-physical model for smart distribution grid are analyzed by combining with the coupling of information flow and power flow of smart distribution network from the perspective of cyber-physical model. At last, taking 110 kV typical substation as an example, the coupling mechanism and function of power flow and information flow is studied. 展开更多
关键词 SMART distribution NETWORK SMART SUBSTATION Cyber-Physical MODELING
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Grid tie inverter energy stabilizing in smart distribution grid with energy storage
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作者 孙秋野 李大双 +1 位作者 褚恩辉 张艺缤 《Journal of Central South University》 SCIE EI CAS 2014年第6期2298-2305,共8页
With the growing deployment of smart distribution grid,it has become urgent to investigate the smart distribution grid behavior during transient faults and improve the system stability.The feasibility of segmenting la... With the growing deployment of smart distribution grid,it has become urgent to investigate the smart distribution grid behavior during transient faults and improve the system stability.The feasibility of segmenting large power grids and multiple smart distribution grids interconnections using energy storage technology for improving the system dynamic stability was studied.The segmentation validity of the large power grids and smart distribution grid inverter output interconnections power system using energy storage technology was proved in terms of theoretical analysis.Then,the influences of the energy storage device location and capacity on the proposed method were discussed in detail.The conclusion is obtained that the ESD optimal locations are allocated at the tie line terminal buses in the interconnected grid,respectively.The effectiveness of the proposed method was verified by simulations in an actual power system. 展开更多
关键词 动态稳定性 储能技术 配电网 逆变器 智能 互连系统 最佳位置 瞬态故障
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Combining Market-Based Control with Distribution Grid Constraints when Coordinating Electric Vehicle Charging
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作者 Geert Deconinck Klaas De Craemer Bert Claessens 《Engineering》 SCIE EI 2015年第4期453-465,共13页
The charging of electric vehicles(EVs) impacts the distribution grid, and its cost depends on the price of electricity when charging. An aggregator that is responsible for a large fleet of EVs can use a market-based c... The charging of electric vehicles(EVs) impacts the distribution grid, and its cost depends on the price of electricity when charging. An aggregator that is responsible for a large fleet of EVs can use a market-based control algorithm to coordinate the charging of these vehicles, in order to minimize the costs. In such an optimization, the operational parameters of the distribution grid, to which the EVs are connected, are not considered. This can lead to violations of the technical constraints of the grid(e.g., undervoltage, phase unbalances); for example, because many vehicles start charging simultaneously when the price is low. An optimization that simultaneously takes the economic and technical aspects into account is complex, because it has to combine time-driven control at the market level with eventdriven control at the operational level. Diff erent case studies investigate under which circumstances the market-based control, which coordinates EV charging, conflicts with the operational constraints of the distribution grid. Especially in weak grids, phase unbalance and voltage issues arise with a high share of EVs. A low-level voltage droop controller at the charging point of the EV can be used to avoid many grid constraint violations, by reducing the charge power if the local voltage is too low. While this action implies a deviation from the cost-optimal operating point, it is shown that this has a very limited impact on the business case of an aggregator, and is able to comply with the technical distribution grid constraints, even in weak distribution grids with many EVs. 展开更多
关键词 电动汽车 充电电源 控制算法 配电网 市场 三相不平衡 驱动控制 违规行为
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Research and Design of Inverter Applied in Solar PV Systems Connected to Distribution Grid
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作者 Nguyen Duc Minh Trinh Trong Chuong +2 位作者 Bui Van Huy Quach Duc Cuong Bui Dinh Thanh 《Journal of Electrical Engineering》 2019年第1期28-38,共11页
This paper presents the results of research on the application of inverter in the grid connected solar photovoltaics (PV) system. The main content of the article is to control the three-phase grid connected inverter t... This paper presents the results of research on the application of inverter in the grid connected solar photovoltaics (PV) system. The main content of the article is to control the three-phase grid connected inverter to meet the requirement of controlling the reactive power to zero at a node of the distribution network while maximizing the active power transmitted to the grid. The control circuits are synthesized on the dq coordinate system and verified on the simulation model by Matlab/Simulink. Both simulation and experimental prototype on 5 kW inverter, being connected to low voltage grid, have been built to show the good results and the practical readiness for implementation. 展开更多
关键词 SVPWM REACTIVE power SOLAR PV grid CONNECTED INVERTER
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Power Quality Issues Concerning Photovoltaic Generation and Electrical Vehicle Loads in Distribution Grids
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作者 Jaan Niitsoo Paul Taklaja +1 位作者 Ivo Palu Joni Klüss 《Smart Grid and Renewable Energy》 2015年第6期164-177,共14页
The high utilization level of renewable generation including residential photovoltaic (PV) systems together with the uncontrolled charging of electric vehicles (EVs) can have a significant impact on load characteristi... The high utilization level of renewable generation including residential photovoltaic (PV) systems together with the uncontrolled charging of electric vehicles (EVs) can have a significant impact on load characteristics in distribution networks. Harmonic content of PV generation, EV charging loads, and their influence on power quality indicators in residential distribution networks are discussed in this paper. For investigating likely power quality scenarios, PV generation and EV charging measurement results including current harmonic amplitude and phase angle values are used and compared with present load characteristics. Different modelling scenarios are analysed and a simplified model of harmonics in PVs and EVs is offered. The results of the study show moderate additional harmonic distortion in residential load current and voltage distortion at the substation’s busbar when PV generation and EV loading are added. The scenarios presented in this paper can be further used for modelling the actual harmonic loads of the PVs and EVs in distribution networks. 展开更多
关键词 Current Measurement Distributed Generation Electric VEHICLES Load Modelling PHOTO Voltaic POWER Quality POWER System HARMONICS
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Research on IPv6 Transition Evolvement and Security Architecture of Smart Distribution Grid Data Communication System
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作者 Xin Miao Xi Chen 《Journal of Energy and Power Engineering》 2012年第1期146-149,共4页
关键词 数据通信系统 配电网设备 安全体系结构 IPV6 智能 演变 数据通信网络 IPV4协议
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Effects of Flicker in a Distribution Grid with High PV Penetration
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作者 Andreas Spring Georg Wirth +2 位作者 Gerd Becker Robert Pardatscher Rolf Witzmann 《Journal of Energy and Power Engineering》 2014年第12期2001-2011,共11页
关键词 配电网 渗透效应 光伏系统 网具 闪变 装机容量 内部连接 电网规划
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Generic Modeling and Control Framework for Power Systems Dominated by Power Converters Connected Through a Passive Transmission and Distribution Grid
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作者 Qing-Chang Zhong Marcio Stefanello 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2024年第1期292-301,共10页
In this paper,a compact mathematical model having an elegant structure,together with a generic control framework,are proposed for generic power systems dominated by power converters that are interconnected through a p... In this paper,a compact mathematical model having an elegant structure,together with a generic control framework,are proposed for generic power systems dominated by power converters that are interconnected through a passive transmission and distribution(T&D)grid,by adopting the port-Hamiltonian(pH)systems theory and the fundamental circuit theory.The models of generic T&D lines are developed and then the model of a generic T&D grid is established.With the proposed control framework,the controlled converters are proven to be passive and Input-to-State Stable(ISS).The compact mathematical model is scalable and can be applied to power systems with multiple power electronic converters with generic passive controllers,passive local loads,and different types of passive T&D lines connected in a meshed configuration without self-loops,so it is very generic.Moreover,the resulting power system is proven to be ISS as well.The analysis is carried out without assumptions on constant frequency/voltage,constant loads,and/or lossless networks,except the need of passivity for all parts involved,and without using the Clarke/Park transformations or the graph theory.To simplify the presentation,three-phase balanced systems are adopted but the results can be easily adapted for single-phase or unbalanced three-phase systems. 展开更多
关键词 Input-to-State Stable(ISS) passivity portHamiltonian(pH)systems Power electronic converters dominated power systems Synchronized and Democratized(SYNDEM)grid architecture
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Data-driven Detection and Identification of Line Parameters with PMU and Unsynchronized SCADA Measurements in Distribution Grids
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作者 Jinping Sun Qifang Chen Mingchao Xia 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2024年第1期261-271,共11页
Line parameters play an important role in the control and management of distribution systems.Currently,phasor measurement unit(PMU)systems and supervisory control and data acquisition(SCADA)systems coexist in distribu... Line parameters play an important role in the control and management of distribution systems.Currently,phasor measurement unit(PMU)systems and supervisory control and data acquisition(SCADA)systems coexist in distribution systems.Unfortunately,SCADA and PMU measurements usually do not match each other,resulting in inaccurate detection and identification of line parameters based on measurements.To solve this problem,a data-driven method is proposed.SCADA measurements are taken as samples and PMU measurements as the population.A probability parameter identification index(PPII)is derived to detect the whole line parameter based on the probability density function(PDF)parameters of the measurements.For parameter identification,a power-loss PDF with the PMU time stamps and a power-loss chronological PDF are derived via kernel density estimation(KDE)and a conditional PDF.Then,the power-loss samples with the PMU time stamps and chronological correlations are generated by the two PDFs of the power loss via the Metropolis-Hastings(MH)algorithm.Finally,using the power-loss samples and PMU current measurements,the line parameters are identified using the total least squares(TLS)algorithm.Hardware simulations demonstrate the effectiveness of the proposed method for distribution network line parameter detection and identification. 展开更多
关键词 distribution systems line parameter detection and identification probability density function sampling algorithm the time skew of PMU and SCADA measurements
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Soft Open Point Planning in Renewable-dominated Distribution Grids with Building Thermal Storage 被引量:3
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作者 Tiance Zhang Jianxiao Wang +3 位作者 Haiwang Zhong Gengyin Li Ming Zhou Dejie Zhao 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2023年第1期244-253,共10页
With an increasing integration of intermittent distributed energy resources(DERs),the consequent voltage excursion and thermal overloading issues limit the self-sufficiency of distribution networks(DNs).The concept of... With an increasing integration of intermittent distributed energy resources(DERs),the consequent voltage excursion and thermal overloading issues limit the self-sufficiency of distribution networks(DNs).The concept of soft open point(SOP)has been proposed as a promising solution to improve the hosting capacity of DNs.In this paper,considering the ability of building thermal storage(BTS)to increase the penetration of renewable energy in DNs,we provide an optimal planning framework for SOP and DER.The optimal planning model is aimed at minimizing the investment and operational costs while respecting various constraints,including the self-sufficiency requirement of the DN,SOP,building thermal storage capacity and DER operations,etc.A steady-state SOP model is formulated and linearized to be incorporated into the planning framework.To make full use of the BTS flexibility provided by ubiquitous buildings,a differential equation model for building thermal dynamics is formulated.A hybrid stochastic/robust optimization approach is adopted to depict the uncertainties in renewable energy and market prices.IEEE 33-bus feeder and a realistic DN in the metropolitan area of Caracas are tested to validate the effectiveness of the proposed framework and method.Case studies show that SOP/BTS plays a complementary and coordinated coupling role in the thermo-electric system,thereby effectively improving the hosting capacity and self-sufficiency of DNs. 展开更多
关键词 Building thermal storage distributed generation planning soft open point thermos-electric system
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Cyber-physical Test Case for Distribution Grid Operation and Control
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作者 Ying Liang Muke Bai +7 位作者 Keyan Liu Dong Liu Donglian Qi Qinglai Guo Xueshun Ye Tianyuan Kang Hui He Bo Chai 《CSEE Journal of Power and Energy Systems》 SCIE EI CSCD 2023年第2期707-721,共15页
In the CPS-oriented power distribution system,a large number of the existing test cases cannot be accessed and reused.That is not conducive to the continuity of the CPS research of the distribution network.In response... In the CPS-oriented power distribution system,a large number of the existing test cases cannot be accessed and reused.That is not conducive to the continuity of the CPS research of the distribution network.In response to above problem,based on an actual distribution network and considering the mapping relationship between cyber systems and physical systems,a computation test case that covers multiple power sources,and multiple types of load is proposed in this paper,and it is suitable for the simulation of multiple types of information system scenarios.In order to satisfy the specific needs of researchers for system topology and data,how to perform cyber contingency analysis,vulnerability assessment and distributed control are also discussed based on the existing topology and data.Researchers can utilize the test case presented in this paper to test their innovative methods in operational analysis,optimization control,and safety analysis for distribution networks.They can also utilize the published topologies and data to design their own test cases based on the methods in this paper. 展开更多
关键词 Cyber contingency analysis cyber-physical test case distributed control vulnerability assessment
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Research on Grid Planning of Dual Power Distribution Network Based on Parallel Ant Colony Optimization Algorithm
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作者 Shuaixiang Wang 《Journal of Electronic Research and Application》 2023年第1期32-41,共10页
A distribution network plays an extremely important role in the safe and efficient operation of a power grid.As the core part of a power grid’s operation,a distribution network will have a significant impact on the s... A distribution network plays an extremely important role in the safe and efficient operation of a power grid.As the core part of a power grid’s operation,a distribution network will have a significant impact on the safety and reliability of residential electricity consumption.it is necessary to actively plan and modify the distribution network’s structure in the power grid,improve the quality of the distribution network,and optimize the planning of the distribution network,so that the network can be fully utilized to meet the needs of electricity consumption.In this paper,a distribution network grid planning algorithm based on the reliability of electricity consumption was completed using ant colony algorithm.For the distribution network structure planning of dual power sources,the parallel ant colony algorithm was used to prove that the premise of parallelism is the interactive process of ant colonies,and the dual power distribution network structure model is established based on the principle of the lowest cost.The artificial ants in the algorithm were compared with real ants in nature,and the basic steps and working principle of the ant colony optimization algorithm was studied with the help of the travelling salesman problem(TSP).Then,the limitations of the ant colony algorithm were analyzed,and an improvement strategy was proposed by using python for digital simulation.The results demonstrated the reliability of model-building and algorithm improvement. 展开更多
关键词 Parallel ant colony optimization algorithm Dual power sources distribution network grid planning
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Grid System Analysis of Urban Flora of Bukhara City (Uzbekistan)
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作者 Abdulla M. Umedov Husniddin K. Esanov 《American Journal of Plant Sciences》 CAS 2024年第2期139-144,共6页
This article presents information on the study of the flora of Uzbekistan based on grid system mapping. The urban flora of the city of Bukhara was researched in it. As a result of research, the territory of Bukhara ci... This article presents information on the study of the flora of Uzbekistan based on grid system mapping. The urban flora of the city of Bukhara was researched in it. As a result of research, the territory of Bukhara city was divided into 85 indexes based on 1 × 1 km<sup>2</sup> grid mapping system. The diversity and density of species in the indexes are determined. The influence of anthropogenic factors on the diversity of species in the indexes is determined. 展开更多
关键词 Bukhara City Urban Flora INDEX grid Map System HERBARIUM Geoinformation
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Influence of Topography on the Distribution and Structure of Woody Plants in the Senegalese Sahel (Sandy Ferlo)
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作者 Moustapha Bassimbe Sagna Aïssatou Ndong Thiam +5 位作者 Khoudia Niang Oumar Sarr Aly Diallo Sekouna Diatta Daouda Ngom Aliou Guissé 《American Journal of Plant Sciences》 CAS 2024年第1期14-28,共15页
This study describes the floristic composition and structure of a woody stand in the Senegalese Sahel, paying particular attention to the edaphic factors of its floristic composition. A stratified inventory considerin... This study describes the floristic composition and structure of a woody stand in the Senegalese Sahel, paying particular attention to the edaphic factors of its floristic composition. A stratified inventory considering the different relief units was adopted. Woody vegetation was surveyed using a dendrometric approach. The results obtained show that the flora is dominated by a few species adapted to drought, such as Balanites aegyptiaca (L.) Del., Calotropis procera Ait. and Boscia senegalensis (Pers.). The distribution of this flora and the structure of the ligneous plants are linked to the topography. In the lowlands, the flora is more diversified and the ligneous plants reach their optimum level of development compared with the higher relief areas. In the lowlands, there are a few woody species which, in the past, were indicative of better climatic conditions. These are Anogeissus leiocarpus (DC.), Commiphora africana (A. Rich.), Feretia apodanthera Del., Loeseneriella africana (A. Smith), Mitragyna inermis (Willd.) and Sclerocarya birrea (A. Rich). It is important that their reintroduction into reforestation projects takes account of their edaphic preference. 展开更多
关键词 Woody Plants distribution TOPOGRAPHY Ferlo Senegal
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Boosting Adversarial Training with Learnable Distribution
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作者 Kai Chen Jinwei Wang +2 位作者 James Msughter Adeke Guangjie Liu Yuewei Dai 《Computers, Materials & Continua》 SCIE EI 2024年第3期3247-3265,共19页
In recent years,various adversarial defense methods have been proposed to improve the robustness of deep neural networks.Adversarial training is one of the most potent methods to defend against adversarial attacks.How... In recent years,various adversarial defense methods have been proposed to improve the robustness of deep neural networks.Adversarial training is one of the most potent methods to defend against adversarial attacks.However,the difference in the feature space between natural and adversarial examples hinders the accuracy and robustness of the model in adversarial training.This paper proposes a learnable distribution adversarial training method,aiming to construct the same distribution for training data utilizing the Gaussian mixture model.The distribution centroid is built to classify samples and constrain the distribution of the sample features.The natural and adversarial examples are pushed to the same distribution centroid to improve the accuracy and robustness of the model.The proposed method generates adversarial examples to close the distribution gap between the natural and adversarial examples through an attack algorithm explicitly designed for adversarial training.This algorithm gradually increases the accuracy and robustness of the model by scaling perturbation.Finally,the proposed method outputs the predicted labels and the distance between the sample and the distribution centroid.The distribution characteristics of the samples can be utilized to detect adversarial cases that can potentially evade the model defense.The effectiveness of the proposed method is demonstrated through comprehensive experiments. 展开更多
关键词 Adversarial training feature space learnable distribution distribution centroid
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A Long-Time-Step-Permitting Tracer Transport Model on the Regular Latitude–Longitude Grid
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作者 Jianghao LI Li DONG 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第3期493-508,共16页
If an explicit time scheme is used in a numerical model, the size of the integration time step is typically limited by the spatial resolution. This study develops a regular latitude–longitude grid-based global three-... If an explicit time scheme is used in a numerical model, the size of the integration time step is typically limited by the spatial resolution. This study develops a regular latitude–longitude grid-based global three-dimensional tracer transport model that is computationally stable at large time-step sizes. The tracer model employs a finite-volume flux-form semiLagrangian transport scheme in the horizontal and an adaptively implicit algorithm in the vertical. The horizontal and vertical solvers are coupled via a straightforward operator-splitting technique. Both the finite-volume scheme's onedimensional slope-limiter and the adaptively implicit vertical solver's first-order upwind scheme enforce monotonicity. The tracer model permits a large time-step size and is inherently conservative and monotonic. Idealized advection test cases demonstrate that the three-dimensional transport model performs very well in terms of accuracy, stability, and efficiency. It is possible to use this robust transport model in a global atmospheric dynamical core. 展开更多
关键词 tracer transport numerical stability latitude–longitude grid
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Simulation of Haloxylon Ammodendron Stand Basic Diameter Structure Based on Fuzzy Distribution Function
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作者 Shaohua Wang Chuanqiang Liu Ting Yang 《Agricultural Sciences》 2024年第1期132-145,共14页
Based on the investigation data of 12 Haloxylon ammodendron plots in the south edge of Gurbantunggut Desert, Fuzzy distribution was introduced into the study of Haloxylon ammodendron base diameter structure fitting ac... Based on the investigation data of 12 Haloxylon ammodendron plots in the south edge of Gurbantunggut Desert, Fuzzy distribution was introduced into the study of Haloxylon ammodendron base diameter structure fitting according to the consistency between the characteristics of Fuzzy distribution function and the distribution series of cumulative percentage of stand base diameter, and the fitting precision and effect of Fuzzy distribution function were discussed. The root mean square error RMSE and determination coefficient R<sup>2</sup> values showed that Fuzzy-Γ<sub>1</sub>, Fuzzy-Γ<sub>2</sub>, Fuzzy-Γ<sub>3</sub>, Fuzzy-Γ<sub>4</sub> had good fitting performance, among which Fuzzy-Γ<sub>1</sub> had relatively high fitting precision, and its parameters were closely related to stand age and density, Fuzzy-Γ<sub>2</sub> distribution function was the second, and Fuzzy-Γ<sub>4</sub> distribution function had the worst fitting effect. By introducing a parameter c from the similarity of four distribution function formulas, a generalized Fuzzy distribution function Fuzzy-Γ<sub>5</sub> is obtained. This function shows the highest fitting accuracy. Most of the values of parameter c are near 1 or 2, which shows that the diameter distribution is mainly approximate to Fuzzy-Γ<sub>1</sub> and Fuzzy-Γ<sub>2</sub>. 展开更多
关键词 Fuzzy distribution Function Haloxylon Ammodendron Base Diameter distribution Stand Factor
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Assessment of Crop Yield in China Simulated by Thirteen Global Gridded Crop Models
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作者 Dezhen YIN Fang LI +3 位作者 Yaqiong LU Xiaodong ZENG Zhongda LIN Yanqing ZHOU 《Advances in Atmospheric Sciences》 SCIE CAS CSCD 2024年第3期420-434,共15页
Global gridded crop models(GGCMs) have been broadly applied to assess the impacts of climate and environmental change and adaptation on agricultural production. China is a major grain producing country, but thus far o... Global gridded crop models(GGCMs) have been broadly applied to assess the impacts of climate and environmental change and adaptation on agricultural production. China is a major grain producing country, but thus far only a few studies have assessed the performance of GGCMs in China, and these studies mainly focused on the average and interannual variability of national and regional yields. Here, a systematic national-and provincial-scale evaluation of the simulations by13 GGCMs [12 from the GGCM Intercomparison(GGCMI) project, phase 1, and CLM5-crop] of the yields of four crops(wheat, maize, rice, and soybean) in China during 1980–2009 was carried out through comparison with crop yield statistics collected from the National Bureau of Statistics of China. Results showed that GGCMI models generally underestimate the national yield of rice but overestimate it for the other three crops, while CLM5-crop can reproduce the national yields of wheat, maize, and rice well. Most GGCMs struggle to simulate the spatial patterns of crop yields. In terms of temporal variability, GGCMI models generally fail to capture the observed significant increases, but some can skillfully simulate the interannual variability. Conversely, CLM5-crop can represent the increases in wheat, maize, and rice, but works less well in simulating the interannual variability. At least one model can skillfully reproduce the temporal variability of yields in the top-10 producing provinces in China, albeit with a few exceptions. This study, for the first time, provides a complete picture of GGCM performance in China, which is important for GGCM development and understanding the reliability and uncertainty of national-and provincial-scale crop yield prediction in China. 展开更多
关键词 global gridded crop model historical crop yield China multi-model evaluation
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Virtual Power Plants for Grid Resilience: A Concise Overview of Research and Applications
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作者 Yijing Xie Yichen Zhang +2 位作者 Wei-Jen Lee Zongli Lin Yacov A.Shamash 《IEEE/CAA Journal of Automatica Sinica》 SCIE EI CSCD 2024年第2期329-343,共15页
The power grid is undergoing a transformation from synchronous generators(SGs) toward inverter-based resources(IBRs). The stochasticity, asynchronicity, and limited-inertia characteristics of IBRs bring about challeng... The power grid is undergoing a transformation from synchronous generators(SGs) toward inverter-based resources(IBRs). The stochasticity, asynchronicity, and limited-inertia characteristics of IBRs bring about challenges to grid resilience. Virtual power plants(VPPs) are emerging technologies to improve the grid resilience and advance the transformation. By judiciously aggregating geographically distributed energy resources(DERs) as individual electrical entities, VPPs can provide capacity and ancillary services to grid operations and participate in electricity wholesale markets. This paper aims to provide a concise overview of the concept and development of VPPs and the latest progresses in VPP operation, with the focus on VPP scheduling and control. Based on this overview, we identify a few potential challenges in VPP operation and discuss the opportunities of integrating the multi-agent system(MAS)-based strategy into the VPP operation to enhance its scalability, performance and resilience. 展开更多
关键词 Climate change renewable energy resources RESILIENCE smart grids virtual power plants(VPPs)
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Red cell distribution width/platelet ratio estimates the 3-year risk of decompensation in Metabolic Dysfunction-Associated Steatotic Liver Disease-induced cirrhosis
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作者 Marcello Dallio Mario Romeo +8 位作者 Paolo Vaia Salvatore Auletta Simone Mammone Marina Cipullo Luigi Sapio Angela Ragone Marco Niosi Silvio Naviglio Alessandro Federico 《World Journal of Gastroenterology》 SCIE CAS 2024年第7期685-704,共20页
BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to deco... BACKGROUND For compensated advanced chronic liver disease(cACLD)patients,the first decompensation represents a dramatically worsening prognostic event.Based on the first decompensation event(DE),the transition to decompensated advanced chronic liver disease(dACLD)can occur through two modalities referred to as acute decompensation(AD)and non-AD(NAD),respectively.Clinically Significant Portal Hypertension(CSPH)is considered the strongest predictor of decompensation in these patients.However,due to its invasiveness and costs,CSPH is almost never evaluated in clinical practice.Therefore,recognizing noninvasively predicting tools still have more appeal across healthcare systems.The red cell distribution width to platelet ratio(RPR)has been reported to be an indicator of hepatic fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease(MASLD).However,its predictive role for the decompensation has never been explored.AIM In this observational study,we investigated the clinical usage of RPR in predicting DEs in MASLD-related cACLD patients.METHODS Fourty controls and 150 MASLD-cACLD patients were consecutively enrolled and followed up(FUP)semiannually for 3 years.At baseline,biochemical,clinical,and Liver Stiffness Measurement(LSM),Child-Pugh(CP),Model for End-Stage Liver Disease(MELD),aspartate aminotransferase/platelet count ratio index(APRI),Fibrosis-4(FIB-4),Albumin-Bilirubin(ALBI),ALBI-FIB-4,and RPR were collected.During FUP,DEs(timing and modaities)were recorded.CSPH was assessed at the baseline and on DE occurrence according to the available Clinical Practice Guidelines.RESULTS Of 150 MASLD-related cACLD patients,43(28.6%)progressed to dACLD at a median time of 28.9 months(29 NAD and 14 AD).Baseline RPR values were significantly higher in cACLD in comparison to controls,as well as MELD,CP,APRI,FIB-4,ALBI,ALBI-FIB-4,and LSM in dACLD-progressing compared to cACLD individuals[all P<0.0001,except for FIB-4(P:0.007)and ALBI(P:0.011)].Receiving operator curve analysis revealed RPR>0.472 and>0.894 as the best cut-offs in the prediction respectively of 3-year first DE,as well as its superiority compared to the other non-invasive tools examined.RPR(P:0.02)and the presence of baseline-CSPH(P:0.04)were significantly and independently associated with the DE.Patients presenting baseline-CSPH and RPR>0.472 showed higher risk of decompensation(P:0.0023).CONCLUSION Altogether these findings suggest the RPR as a valid and potentially applicable non-invasive tool in the prediction of timing and modalities of decompensation in MASLD-related cACLD patients. 展开更多
关键词 Liver cirrhosis Red blood cell distribution width Red blood cell distribution width to platelet ratio Translational Medicine Prognostic biomarker
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