Many unique properties of complex networks result from heterogeneity. The measure and analysis of heterogeneity are important and desirable to the research of the properties and functions of complex networks. In this ...Many unique properties of complex networks result from heterogeneity. The measure and analysis of heterogeneity are important and desirable to the research of the properties and functions of complex networks. In this paper, the rank distribution is proposed as a new statistic feature of complex networks. Based on the rank distribution, a novel measure of the heterogeneity called a normalized entropy of rank distribution （NERD） is proposed. The NERD accords with the normal meaning of heterogeneity within the context of complex networks compared with conventional measures. The heterogeneity of scale-free networks is studied using the NERD. It is shown that scale-free networks become more heterogeneous as the scaling exponent decreases and the NERD of scale-free networks is independent of the number of vertices, which indicates that the NERD is a suitable and effective measure of heterogeneity for networks with different sizes.展开更多
The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional meth...The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional method and presents an extended wet sieving method.The extended method uses both the steel sieves and the nylon filter cloth sieves.The apertures of the cloth sieves are smaller than 0.063 mm and equal 0.048 mm,0.038 mm,0.014 mm,0.012 mm,0.0063 mm,0.004 mm,0.003 mm,0.002 mm,and 0.001 mm,respectively.The extended method uses five steps to separate the general soil into many material sub-groups of gravel,sand,silt and clay with known particle size ranges.The complete PSD of the general soil is then calculated from the dry masses of the individual material sub-groups.The extended method is demonstrated with a general soil of completely decomposed granite(CDG)in Hong Kong,China.The silt and clay materials with different particle size ranges are further examined,checked and verified using stereomicroscopic observation,physical and chemical property tests.The results further confirm the correctness of the extended wet sieving method.展开更多
A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas detector.To address the issue of long process...A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas detector.To address the issue of long processing times in traditional offline position reconstruction methods,this paper proposes a field programmable gate array based online position reconstruction method utilizing the micro-time projection chamber principle.This method encapsulates key technical aspects:a self-adaptive serial link technique built upon the dynamical adjustment of the delay chain length,fast sorting,a coordinate-matching technique based on the mapping between signal timestamps and random access memory(RAM)addresses,and a precise start point-merging technique utilizing a circular combined RAM.The performance test of the selfadaptive serial link shows that the bit error rate of the link is better than 10-12 at a confidence level of 99%,ensuring reliable data transmission.The experiment utilizing the readout electronics and Micromegas detector shows a spatial resolution of approximately 1.4 mm,surpassing the current method’s resolution level of 5 mm.The beam experiment confirms that the readout electronics system can obtain the flux spatial distribution of neutron beams online,thus validating the feasibility of the position reconstruction method.The online position reconstruction method avoids traditional methods,such as bubble sorting and traversal searching,simplifies the design of the logic firmware,and reduces the time complexity from O(n2)to O(n).This study contributes to the advancement in measuring neutron beam flux for BNCT.展开更多
In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie distribution.The traditional approach to obtaining ...In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie distribution.The traditional approach to obtaining the Tweedie regression model involves training on a centralized dataset,when the data is provided by multiple parties,training a privacy-preserving Tweedie regression model without exchanging raw data becomes a challenge.To address this issue,this study introduces a novel vertical federated learning-based Tweedie regression algorithm for multi-party auto insurance rate setting in data silos.The algorithm can keep sensitive data locally and uses privacy-preserving techniques to achieve intersection operations between the two parties holding the data.After determining which entities are shared,the participants train the model locally using the shared entity data to obtain the local generalized linear model intermediate parameters.The homomorphic encryption algorithms are introduced to interact with and update the model intermediate parameters to collaboratively complete the joint training of the car insurance rate-setting model.Performance tests on two publicly available datasets show that the proposed federated Tweedie regression algorithm can effectively generate Tweedie regression models that leverage the value of data fromboth partieswithout exchanging data.The assessment results of the scheme approach those of the Tweedie regressionmodel learned fromcentralized data,and outperformthe Tweedie regressionmodel learned independently by a single party.展开更多
Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheime...Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheimer’s disease affects the entire brain,further research is needed to elucidate alterations in mitochondrial metabolism in the brain as a whole.Here,we investigated the expression of several important mitochondrial biogenesis-related cytokines in multiple brain regions after treatment with neural stem cell-derived exosomes and used a combination of whole brain clearing,immunostaining,and lightsheet imaging to clarify their spatial distribution.Additionally,to clarify whether the sirtuin 1(SIRT1)-related pathway plays a regulatory role in neural stem cell-de rived exosomes interfering with mitochondrial functional changes,we generated a novel nervous system-SIRT1 conditional knoc kout AP P/PS1mouse model.Our findings demonstrate that neural stem cell-de rived exosomes significantly increase SIRT1 levels,enhance the production of mitochondrial biogenesis-related fa ctors,and inhibit astrocyte activation,but do not suppress amyloid-βproduction.Thus,neural stem cell-derived exosomes may be a useful therapeutic strategy for Alzheimer’s disease that activates the SIRT1-PGC1αsignaling pathway and increases NRF1 and COXIV synthesis to improve mitochondrial biogenesis.In addition,we showed that the spatial distribution of mitochondrial biogenesis-related factors is disrupted in Alzheimer’s disease,and that neural stem cell-derived exosome treatment can reverse this effect,indicating that neural stem cell-derived exosomes promote mitochondrial biogenesis.展开更多
Based on the situation and progress of marine oil/gas exploration in the Sichuan Basin,SW China,the whole petroleum system is divided for marine carbonate rocks of the basin according to the combinations of hydrocarbo...Based on the situation and progress of marine oil/gas exploration in the Sichuan Basin,SW China,the whole petroleum system is divided for marine carbonate rocks of the basin according to the combinations of hydrocarbon accumulation elements,especially the source rock.The hydrocarbon accumulation characteristics of each whole petroleum system are analyzed,the patterns of integrated conventional and unconventional hydrocarbon accumulation are summarized,and the favorable exploration targets are proposed.Under the control of multiple extensional-convergent tectonic cycles,the marine carbonate rocks of the Sichuan Basin contain three sets of regional source rocks and three sets of regional cap rocks,and can be divided into the Cambrian,Silurian and Permian whole petroleum systems.These whole petroleum systems present mainly independent hydrocarbon accumulation,containing natural gas of affinity individually.Locally,large fault zones run through multiple whole petroleum systems,forming a fault-controlled complex whole petroleum system.The hydrocarbon accumulation sequence of continental shelf facies shale gas accumulation,marginal platform facies-controlled gas reservoirs,and intra-platform fault-and facies-controlled gas reservoirs is common in the whole petroleum system,with a stereoscopic accumulation and orderly distribution pattern.High-quality source rock is fundamental to the formation of large gas fields,and natural gas in a whole petroleum system is generally enriched near and within the source rocks.The development and maintenance of large-scale reservoirs are essential for natural gas enrichment,multiple sources,oil and gas transformation,and dynamic adjustment are the characteristics of marine petroleum accumulation,and good preservation conditions are critical to natural gas accumulation.Large-scale marginal-platform reef-bank facies zones,deep shale gas,and large-scale lithological complexes related to source-connected faults are future marine hydrocarbon exploration targets in the Sichuan Basin.展开更多
The integration of distributed generation brings in new challenges for the operation of distribution networks,including out-of-limit voltage and power flow control.Soft open points(SOP)are new power electronic devices...The integration of distributed generation brings in new challenges for the operation of distribution networks,including out-of-limit voltage and power flow control.Soft open points(SOP)are new power electronic devices that can flexibly control active and reactive power flows.With the exception of active power output,photovoltaic(PV)devices can provide reactive power compensation through an inverter.Thus,a synergetic optimization operation method for SOP and PV in a distribution network is proposed.A synergetic optimization model was developed.The voltage deviation,network loss,and ratio of photovoltaic abandonment were selected as the objective functions.The PV model was improved by considering the three reactive power output modes of the PV inverter.Both the load fluctuation and loss of the SOP were considered.Three multi-objective optimization algorithms were used,and a compromise optimal solution was calculated.Case studies were conducted using an IEEE 33-node system.The simulation results indicated that the SOP and PVs complemented each other in terms of active power transmission and reactive power compensation.Synergetic optimization improves power control capability and flexibility,providing better power quality and PV consumption rate.展开更多
On February 6,2023,a devastating earthquake with a moment magnitude of M_(W)7.8 struck the town of Pazarcik in south-central Türkiye,followed by another powerful earthquake with a moment magnitude of M_(W)7.6 tha...On February 6,2023,a devastating earthquake with a moment magnitude of M_(W)7.8 struck the town of Pazarcik in south-central Türkiye,followed by another powerful earthquake with a moment magnitude of M_(W)7.6 that struck the nearby city of Elbistan 9 h later.To study the characteristics of surface deformation caused by this event and the influence of fault rupture,this study calculated the static coseismic deformation of 56 stations and dynamic displacement waveforms of 15 stations using data from the Turkish national fixed global navigation satellite system(GNSS)network.A maximum static coseismic displacement of 0.38 m for the M_(W)7.8 Kahramanmaras earthquake was observed at station ANTE,36 km from the epicenter,and a maximum dynamic coseismic displacement of 4.4 m for the M_(W)7.6 Elbistan earthquake was observed at station EKZ1,5 km from the epicenter.The rupture-slip distributions of the two earthquakes were inverted using GNSS coseismic deformation as a constraint.The results showed that the Kahramanmaras earthquake rupture segment was distinct and exposed on the ground,resulting in significant rupture slip along the Amanos and Pazarcik fault segments of the East Anatolian Fault.The maximum slip in the Pazarcik fault segment was 10.7 m,and rupture occurred at depths of 0–15 km.In the Cardak fault region,the Elbistan earthquake caused significant ruptures at depths of 0–12 km,with the largest amount of slip reaching 11.6 m.The Coulomb stress change caused by the Kahramanmaras earthquake rupture along the Cardak fault segment was approximately 2 bars,and the area of increased Coulomb stress corresponded to the subsequent rupture region of the M_(W)7.6 earthquake.Thus,it is likely that the M_(W)7.8 earthquake triggered or promoted the M_(W)7.6 earthquake.Based on the cumulative stress impact of the M_(W)7.8 and M_(W)7.6 events,the southwestern segment of the East Anatolian Fault,specifically the Amanos fault segment,experienced a Coulomb rupture stress change exceeding 2 bars,warranting further attention to assess its future seismic hazard risk.展开更多
DEAR EDITOR,Biogeography is a scientific field dedicated to the investigation of the origins and distribution patterns of organisms,as well as predicting future alterations in their geographical distributions(Cox&...DEAR EDITOR,Biogeography is a scientific field dedicated to the investigation of the origins and distribution patterns of organisms,as well as predicting future alterations in their geographical distributions(Cox&Moore,2005).However,the majority of conclusions drawn within the field of biogeography are hypothetical.Rigorous testing of these biogeographic hypotheses remains a considerable challenge.This paper presents the concept of“integrative biogeography”,which emphasizes the experimental testing of biogeographic hypotheses through studies on geological history,as well as biotic and abiotic factors(Figure 1).展开更多
A wide survey was conducted to study plant-parasitic nematodes(PPNs)associated with Prunus groves in Spain.This research aimed to determine the prevalence and distribution of PPNs in Prunus groves,as well as the influ...A wide survey was conducted to study plant-parasitic nematodes(PPNs)associated with Prunus groves in Spain.This research aimed to determine the prevalence and distribution of PPNs in Prunus groves,as well as the influence of explanatory variables describing soil,climate and agricultural management in structuring the variation of PPNs community composition.A total of 218 sampling sites were surveyed and 84 PPN species belonging to 32 genera were identified based of an integrative taxonomic approach.PPN species considered as potential limiting factors in Prunus production,such as Meloidogyne arenaria,M.incognita,M.javanica,Pratylenchus penetrans and P.vulnus,were identified in this survey.Seven soil physico-chemical(C,Mg,N,Na,OM,P,pH and clay,loamy sand and sandy loam texture classes),four climate(Bio04,Bio05,Bio13 and Bio14)and four agricultural management variables(grove-use history less than 10 years,irrigation,apricot seedling rootstock,and Montclar rootstock)were identified as the most influential variables driving spatial patterns of PPNs communities.In particular,younger plantations showed higher values for species richness and diversity indices than groves cultivated for more than 20 years with Prunus spp.Our study increases the knowledge of the distribution and prevalence of PPNs associated with Prunus rhizosphere,as well as on the influence of explanatory variables driving the spatial structure PPNs communities,which has important implications for the successful design of sustainable management strategies in the future in this agricultural system.展开更多
Ten rock samples consisting of one pyroclastic density current(PDC1)deposit,seven lava flows(LF1–7),and two summit lava domes(LD1,2)were studied to understand the petrogenesis and magma dynamics at Mt.Sumbing.The str...Ten rock samples consisting of one pyroclastic density current(PDC1)deposit,seven lava flows(LF1–7),and two summit lava domes(LD1,2)were studied to understand the petrogenesis and magma dynamics at Mt.Sumbing.The stratigraphy is arranged as LF1,PDC1,LF2,LF3,LF4,LF5,LF6,LF7,LD1,and LD2;furthermore,these rocks were divided into two types.TypeⅠ,observed in the oldest(LF1)sample,has poor MgO and high Ba/Nb,Th/Yb and Sr.The remaining samples(PDC1–LD2)represent typeⅡ,characterized by high MgO and low Ba/Nb,Th/Yb and Sr values.We suggest that type I is derived from AOC(altered oceanic crust)-rich melts that underwent significant crustal assimilation,while typeⅡoriginates from mantle-rich melts with less significant crustal assimilation.The early stage of typeⅡmagma(PDC1–LF3)was considered a closed system,evolving basaltic andesite into andesite(55.0–60.2 wt%SiO_(2))with a progressively increasing phenocryst(0.30–0.48φ_(PC))and decreasing crystal size distribution(CSD)slope(from-3.9 to-2.9).The evidence of fluctuating silica and phenocryst contents(between 55.9–59.7 wt%and 0.25–0.41φ_(PC),respectively),coupled with the kinked and steep(from-5.0 to-3.3)CSD curves imply the interchanging condition between open(i.e.,magma mixing)and closed magmatic systems during the middle stage(LF4–LF6).Finally,it underwent to closed system again during the final stage(LF7–LD2)because the magma reached dacitic composition(at most 68.9 wt%SiO_(2))with abundant phenocryst(0.38–0.45φ_(PC))and gentle CSD slope(from-4.1 to-1.2).展开更多
Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechan...Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechanical properties of the culm are mainly determined by lignin,which is affected by the light environment.However,little is known about whether the light environment can be sufficiently improved by changing the population distribution to inhibit culm lodging.Therefore,in this study,we used the wheat cultivar“Xinong 979”to establish a low-density homogeneous distribution treatment(LD),high-density homogeneous distribution treatment(HD),and high-density heterogeneous distribution treatment(HD-h)to study the regulatory effects and mechanism responsible for differences in the lodging resistance of wheat culms under different population distributions.Compared with LD,HD significantly reduced the light transmittance in the middle and basal layers of the canopy,the net photosynthetic rate in the middle and lower leaves of plants,the accumulation of lignin in the culm,and the breaking resistance of the culm,and thus the lodging index values increased significantly,with lodging rates of 67.5%in 2020–2021 and 59.3%in 2021–2022.Under HD-h,the light transmittance and other indicators in the middle and basal canopy layers were significantly higher than those under HD,and the lodging index decreased to the point that no lodging occurred.Compared with LD,the activities of phenylalanine ammonia-Lyase(PAL),4-coumarate:coenzyme A ligase(4CL),catechol-O-methyltransferase(COMT),and cinnamyl-alcohol dehydrogenase(CAD)in the lignin synthesis pathway were significantly reduced in the culms under HD during the critical period for culm formation,and the relative expression levels of TaPAL,Ta4CL,TaCOMT,and TaCAD were significantly downregulated.However,the activities of lignin synthesis-related enzymes and their gene expression levels were significantly increased under HD-h compared with HD.A partial least squares path modeling analysis found significant positive effects between the canopy light environment,the photosynthetic capacity of the middle and lower leaves of plants,lignin synthesis and accumulation,and lodging resistance in the culms.Thus,under conventional high-density planting,the risk of wheat lodging was significantly higher.Accordingly,the canopy light environment can be optimized by changing the heterogeneity of the population distribution to improve the photosynthetic capacity of the middle and lower leaves of plants,promote lignin accumulation in the culm,and enhance lodging resistance in wheat.These findings provide a basis for understanding the mechanism responsible for the lower mechanical strength of the culm under high-yield wheat cultivation,and a theoretical basis and for developing technical measures to enhance lodging resistance.展开更多
The secure and normal operation of distributed networks is crucial for accurate parameter estimation.However,distributed networks are frequently susceptible to Byzantine attacks.Considering real-life scenarios,this pa...The secure and normal operation of distributed networks is crucial for accurate parameter estimation.However,distributed networks are frequently susceptible to Byzantine attacks.Considering real-life scenarios,this paper investigates a probability Byzantine(PB)attack,utilizing a Bernoulli distribution to simulate the attack probability.Historically,additional detection mechanisms are used to mitigate such attacks,leading to increased energy consumption and burdens on distributed nodes,consequently diminishing operational efficiency.Differing from these approaches,an adaptive updating distributed estimation algorithm is proposed to mitigate the impact of PB attacks.In the proposed algorithm,a penalty strategy is initially incorporated during data updates to weaken the influence of the attack.Subsequently,an adaptive fusion weight is employed during data fusion to merge the estimations.Additionally,the reason why this penalty term weakens the attack has been analyzed,and the performance of the proposed algorithm is validated through simulation experiments.展开更多
The elemental distribution and microstructure near the surface of high-Mn/Al austenitic low-density steel were investigated after isothermal holding at temperatures of 900-1200℃ in different atmospheres,including air...The elemental distribution and microstructure near the surface of high-Mn/Al austenitic low-density steel were investigated after isothermal holding at temperatures of 900-1200℃ in different atmospheres,including air,N_(2),and N_(2)+CO_(2).No ferrite was formed near the surface of the experimental steel during isothermal holding at 900 and 1000℃ in air,while ferrite was formed near the steel sur-face at holding temperatures of 1100 and 1200℃.The ferrite fraction was larger at 1200℃ because more C and Mn diffused to the sur-face,exuded from the steel,and then reacted with N and O to form oxidation products.The thickness of the compound scale increased owing to the higher diffusion rate at higher temperatures.In addition,after isothermal holding at 1100℃ in N_(2),the Al content near the surface slightly decreased,while the C and Mn contents did not change.Therefore,no ferrite was formed near the surface.However,the near-surface C and Al contents decreased after holding at 1100℃in the N_(2)+CO_(2)mixed atmosphere,resulting in the formation of a small amount of ferrite.The compound scale was thickest in N_(2),followed by the N_(2)+CO_(2)mixed atmosphere,and thinnest in air.Overall,the element loss and ferrite fraction were largest after holding in air at the same temperature.The differences in element loss and ferrite frac-tion between in N_(2) and N_(2)+CO_(2)atmospheres were small,but the compound scale formed in N_(2) was significantly thicker.According to these results,N_(2)+CO_(2)is the ideal heating atmosphere for the industrial production of high-Mn/Al austenitic low-density steel.展开更多
Crude oil scheduling optimization is an effective method to enhance the economic benefits of oil refining.But uncertainties,including uncertain demands of crude distillation units(CDUs),might make the production plans...Crude oil scheduling optimization is an effective method to enhance the economic benefits of oil refining.But uncertainties,including uncertain demands of crude distillation units(CDUs),might make the production plans made by the traditional deterministic optimization models infeasible.A data-driven Wasserstein distributionally robust chance-constrained(WDRCC)optimization approach is proposed in this paper to deal with demand uncertainty in crude oil scheduling.First,a new deterministic crude oil scheduling optimization model is developed as the basis of this approach.The Wasserstein distance is then used to build ambiguity sets from historical data to describe the possible realizations of probability distributions of uncertain demands.A cross-validation method is advanced to choose suitable radii for these ambiguity sets.The deterministic model is reformulated as a WDRCC optimization model for crude oil scheduling to guarantee the demand constraints hold with a desired high probability even in the worst situation in ambiguity sets.The proposed WDRCC model is transferred into an equivalent conditional value-at-risk representation and further derived as a mixed-integer nonlinear programming counterpart.Industrial case studies from a real-world refinery are conducted to show the effectiveness of the proposed method.Out-of-sample tests demonstrate that the solution of the WDRCC model is more robust than those of the deterministic model and the chance-constrained model.展开更多
The Hotan Prefecture of Xinjiang Uygur Autonomous Region,China belongs to arid desert climate,with significant soil salinization issues.The study selected six rivers in Hotan Prefecture(Pishan,Qaraqash,Yurungqash,Cell...The Hotan Prefecture of Xinjiang Uygur Autonomous Region,China belongs to arid desert climate,with significant soil salinization issues.The study selected six rivers in Hotan Prefecture(Pishan,Qaraqash,Yurungqash,Celle,Kriya,and Niya rivers)to explore the spatial distribution of soil salinization in this area and its underlying mechanisms.Sampling was conducted along each river's watershed,from the Gobi in the upper reaches,through the anthropogenic impact area in the middle reaches,to the desert area in the lower reaches.Soil physical-chemical indicators,including total soluble salts,pH,K+,Na+,Ca2+,Mg2+,SO42-,Cl-,CO32-,HCO3-,organic matter,available nitrogen,available phosphorus,and available potassium,were tested,along with the total dissolved solids of surface water and groundwater.The results revealed that the soil water and nutrient contents in anthropogenic impact area were higher than those in Gobi and desert areas,while the pH and total soluble salts were lower than those in Gobi and desert areas.The ions in the soil of the study area were primarily Cl-,SO42-,K+,and Na+,and the ion concentration of soil salt were positively correlated with surface water and groundwater.Overall,the study area exhibited low soil water content,low clay content,infertile soil,and high soil salinization,dominated by weak to moderate chloride-sulfate types.Compared with Gobi and desert areas,the soil in anthropogenic impact area had higher soil water content,lower pH,lower soluble salts,and higher nutrients,indicating that human farming activities help mitigate salinization.These findings have practical implications for guiding the scientific prevention and control of soil salinization in the arid areas and for promoting sustainable agricultural development.展开更多
Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in vivo.Methods Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body w...Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in vivo.Methods Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body weight).The fluorescence intensity(FI)in observed organs was measured using the IVIS Spectrum at 0.5,1,2,and 4 h after administration.Histopathology was performed to corroborate these findings.Results In the 100 nm group,the FI of the stomach and small intestine were highest at 0.5 h,and the FI of the large intestine,excrement,lung,kidney,liver,and skeletal muscles were highest at 4 h compared with the control group(P<0.05).In the 3μm group,the FI only increased in the lung at 2 h(P<0.05).In the 10μm group,the FI increased in the large intestine and excrement at 2 h,and in the kidney at 4 h(P<0.05).The presence of nano-/microplastics in tissues was further verified by histopathology.The peak time of nanoplastic absorption in blood was confirmed.Conclusion Nanoplastics translocated rapidly to observed organs/tissues through blood circulation;however,only small amounts of MPs could penetrate the organs.展开更多
Vegetable fields are often contaminated by heavy metals,and Spodoptera exigua is a major vegetable pest which is stressed by heavy metals mainly by feeding.In this study,cadmium accumulation in the tissues of S.exigua...Vegetable fields are often contaminated by heavy metals,and Spodoptera exigua is a major vegetable pest which is stressed by heavy metals mainly by feeding.In this study,cadmium accumulation in the tissues of S.exigua exposed to cadmium and its effects on the growth and development of the parents and the offspring were investigated.Under the stress of different concentrations of cadmium(0.2,3.2,and 51.2 mg kg^(-1)),the cadmium content in each tissue of S.exigua increased in a dose-dependent manner.At the larval stage,the highest cadmium accumulation was found in midgut in all three cadmium treatments,but at the adult stage,the highest cadmium content was found in fat body.In addition,the cadmium content in ovaries was much higher than in testes.When F1S.exigua was stressed by cadmium and the F_(2)generation was not fed a cadmium-containing diet,the larval survival,pupation rate,emergence rate and fecundity of the F_(2)generation were significantly reduced in the 51.2 mg kg^(-1)treatment compared to the corresponding F1generation.Even in the F_(2)generation of the 3.2 mg kg^(-1)treatment,the fecundity was significantly lower than in the parental generation.The fecundity of the only-female stressed treatment was significantly lower than that of the only-male stressed treatment at the 3.2 and 51.2 mg kg^(-1)cadmium exposure levels.When only mothers were stressed at the larval stage,the fecundity of the F_(2)generation was significantly lower than that of the F1generation in the 51.2 mg kg^(-1)treatment,and it was also significantly lower than in the 3.2 and 0.2 mg kg^(-1)treatments.The results of our study can provide useful information for forecasting the population increase trends under different heavy metal stress conditions and for the reliable environmental risk assessment of heavy metal pollution.展开更多
Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneuro...Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.展开更多
The generation and propagation mechanism of strong nonlinear waves in the South China Sea is an essential research area. In this study, the third-generation wave model WAVEWATCH Ⅲ is employed to simulate wave fields ...The generation and propagation mechanism of strong nonlinear waves in the South China Sea is an essential research area. In this study, the third-generation wave model WAVEWATCH Ⅲ is employed to simulate wave fields under extreme sea states. The model, integrating the ST6 source term, is validated against observed data, demonstrating its credibility. The spatial distribution of the occurrence probability of strong nonlinear waves during typhoons is shown, and the waves in the straits and the northeastern part of the South China Sea show strong nonlinear characteristics. The high-order spectral model HOS-ocean is employed to simulate the random wave surface series beneath five different platform areas. The waves during the typhoon exhibit strong nonlinear characteristics, and freak waves exist. The space-varying probability model is established to describe the short-term probability distribution of nonlinear wave series. The exceedance probability distributions of the wave surface beneath different platform areas are compared and analyzed. The results show that with an increase in the platform area, the probability of a strong nonlinear wave beneath the platform increases.展开更多
基金Project supported by the National Natural Science Foundation of China （Grant No 70501032）.
文摘Many unique properties of complex networks result from heterogeneity. The measure and analysis of heterogeneity are important and desirable to the research of the properties and functions of complex networks. In this paper, the rank distribution is proposed as a new statistic feature of complex networks. Based on the rank distribution, a novel measure of the heterogeneity called a normalized entropy of rank distribution （NERD） is proposed. The NERD accords with the normal meaning of heterogeneity within the context of complex networks compared with conventional measures. The heterogeneity of scale-free networks is studied using the NERD. It is shown that scale-free networks become more heterogeneous as the scaling exponent decreases and the NERD of scale-free networks is independent of the number of vertices, which indicates that the NERD is a suitable and effective measure of heterogeneity for networks with different sizes.
基金The work described in this paper was partially supported by grants from the Research Grant Council of the Hong Kong Special Administrative Region,China(Project Nos.HKU 17207518 and R5037-18).
文摘The traditional standard wet sieving method uses steel sieves with aperture?0.063 mm and can only determine the particle size distribution(PSD)of gravel and sand in general soil.This paper extends the traditional method and presents an extended wet sieving method.The extended method uses both the steel sieves and the nylon filter cloth sieves.The apertures of the cloth sieves are smaller than 0.063 mm and equal 0.048 mm,0.038 mm,0.014 mm,0.012 mm,0.0063 mm,0.004 mm,0.003 mm,0.002 mm,and 0.001 mm,respectively.The extended method uses five steps to separate the general soil into many material sub-groups of gravel,sand,silt and clay with known particle size ranges.The complete PSD of the general soil is then calculated from the dry masses of the individual material sub-groups.The extended method is demonstrated with a general soil of completely decomposed granite(CDG)in Hong Kong,China.The silt and clay materials with different particle size ranges are further examined,checked and verified using stereomicroscopic observation,physical and chemical property tests.The results further confirm the correctness of the extended wet sieving method.
基金supported by the National Natural Science Foundation of China(No.12075237)。
文摘A new measurement method for the spatial distribution of neutron beam flux in boron neutron capture therapy(BNCT)is being developed based on the two-dimensional Micromegas detector.To address the issue of long processing times in traditional offline position reconstruction methods,this paper proposes a field programmable gate array based online position reconstruction method utilizing the micro-time projection chamber principle.This method encapsulates key technical aspects:a self-adaptive serial link technique built upon the dynamical adjustment of the delay chain length,fast sorting,a coordinate-matching technique based on the mapping between signal timestamps and random access memory(RAM)addresses,and a precise start point-merging technique utilizing a circular combined RAM.The performance test of the selfadaptive serial link shows that the bit error rate of the link is better than 10-12 at a confidence level of 99%,ensuring reliable data transmission.The experiment utilizing the readout electronics and Micromegas detector shows a spatial resolution of approximately 1.4 mm,surpassing the current method’s resolution level of 5 mm.The beam experiment confirms that the readout electronics system can obtain the flux spatial distribution of neutron beams online,thus validating the feasibility of the position reconstruction method.The online position reconstruction method avoids traditional methods,such as bubble sorting and traversal searching,simplifies the design of the logic firmware,and reduces the time complexity from O(n2)to O(n).This study contributes to the advancement in measuring neutron beam flux for BNCT.
基金This research was funded by the National Natural Science Foundation of China(No.62272124)the National Key Research and Development Program of China(No.2022YFB2701401)+3 种基金Guizhou Province Science and Technology Plan Project(Grant Nos.Qiankehe Paltform Talent[2020]5017)The Research Project of Guizhou University for Talent Introduction(No.[2020]61)the Cultivation Project of Guizhou University(No.[2019]56)the Open Fund of Key Laboratory of Advanced Manufacturing Technology,Ministry of Education(GZUAMT2021KF[01]).
文摘In the assessment of car insurance claims,the claim rate for car insurance presents a highly skewed probability distribution,which is typically modeled using Tweedie distribution.The traditional approach to obtaining the Tweedie regression model involves training on a centralized dataset,when the data is provided by multiple parties,training a privacy-preserving Tweedie regression model without exchanging raw data becomes a challenge.To address this issue,this study introduces a novel vertical federated learning-based Tweedie regression algorithm for multi-party auto insurance rate setting in data silos.The algorithm can keep sensitive data locally and uses privacy-preserving techniques to achieve intersection operations between the two parties holding the data.After determining which entities are shared,the participants train the model locally using the shared entity data to obtain the local generalized linear model intermediate parameters.The homomorphic encryption algorithms are introduced to interact with and update the model intermediate parameters to collaboratively complete the joint training of the car insurance rate-setting model.Performance tests on two publicly available datasets show that the proposed federated Tweedie regression algorithm can effectively generate Tweedie regression models that leverage the value of data fromboth partieswithout exchanging data.The assessment results of the scheme approach those of the Tweedie regressionmodel learned fromcentralized data,and outperformthe Tweedie regressionmodel learned independently by a single party.
基金supported by the National Natural Science Foundation of China,Nos.82171194 and 81974155(both to JL)the Shanghai Municipal Science and Technology Commission Medical Guide Project,No.16411969200(to WZ)Shanghai Municipal Science and Technology Commission Biomedical Science and Technology Project,No.22S31902600(to JL)。
文摘Mitochondrial dysfunction is a hallmark of Alzheimer’s disease.We previously showed that neural stem cell-derived extracellular vesicles improved mitochondrial function in the cortex of AP P/PS1 mice.Because Alzheimer’s disease affects the entire brain,further research is needed to elucidate alterations in mitochondrial metabolism in the brain as a whole.Here,we investigated the expression of several important mitochondrial biogenesis-related cytokines in multiple brain regions after treatment with neural stem cell-derived exosomes and used a combination of whole brain clearing,immunostaining,and lightsheet imaging to clarify their spatial distribution.Additionally,to clarify whether the sirtuin 1(SIRT1)-related pathway plays a regulatory role in neural stem cell-de rived exosomes interfering with mitochondrial functional changes,we generated a novel nervous system-SIRT1 conditional knoc kout AP P/PS1mouse model.Our findings demonstrate that neural stem cell-de rived exosomes significantly increase SIRT1 levels,enhance the production of mitochondrial biogenesis-related fa ctors,and inhibit astrocyte activation,but do not suppress amyloid-βproduction.Thus,neural stem cell-derived exosomes may be a useful therapeutic strategy for Alzheimer’s disease that activates the SIRT1-PGC1αsignaling pathway and increases NRF1 and COXIV synthesis to improve mitochondrial biogenesis.In addition,we showed that the spatial distribution of mitochondrial biogenesis-related factors is disrupted in Alzheimer’s disease,and that neural stem cell-derived exosome treatment can reverse this effect,indicating that neural stem cell-derived exosomes promote mitochondrial biogenesis.
基金Supported by the National Natural Science Foundation of China(42090022)。
文摘Based on the situation and progress of marine oil/gas exploration in the Sichuan Basin,SW China,the whole petroleum system is divided for marine carbonate rocks of the basin according to the combinations of hydrocarbon accumulation elements,especially the source rock.The hydrocarbon accumulation characteristics of each whole petroleum system are analyzed,the patterns of integrated conventional and unconventional hydrocarbon accumulation are summarized,and the favorable exploration targets are proposed.Under the control of multiple extensional-convergent tectonic cycles,the marine carbonate rocks of the Sichuan Basin contain three sets of regional source rocks and three sets of regional cap rocks,and can be divided into the Cambrian,Silurian and Permian whole petroleum systems.These whole petroleum systems present mainly independent hydrocarbon accumulation,containing natural gas of affinity individually.Locally,large fault zones run through multiple whole petroleum systems,forming a fault-controlled complex whole petroleum system.The hydrocarbon accumulation sequence of continental shelf facies shale gas accumulation,marginal platform facies-controlled gas reservoirs,and intra-platform fault-and facies-controlled gas reservoirs is common in the whole petroleum system,with a stereoscopic accumulation and orderly distribution pattern.High-quality source rock is fundamental to the formation of large gas fields,and natural gas in a whole petroleum system is generally enriched near and within the source rocks.The development and maintenance of large-scale reservoirs are essential for natural gas enrichment,multiple sources,oil and gas transformation,and dynamic adjustment are the characteristics of marine petroleum accumulation,and good preservation conditions are critical to natural gas accumulation.Large-scale marginal-platform reef-bank facies zones,deep shale gas,and large-scale lithological complexes related to source-connected faults are future marine hydrocarbon exploration targets in the Sichuan Basin.
基金supported by the Science and Technology Project of SGCC(kj2022-075).
文摘The integration of distributed generation brings in new challenges for the operation of distribution networks,including out-of-limit voltage and power flow control.Soft open points(SOP)are new power electronic devices that can flexibly control active and reactive power flows.With the exception of active power output,photovoltaic(PV)devices can provide reactive power compensation through an inverter.Thus,a synergetic optimization operation method for SOP and PV in a distribution network is proposed.A synergetic optimization model was developed.The voltage deviation,network loss,and ratio of photovoltaic abandonment were selected as the objective functions.The PV model was improved by considering the three reactive power output modes of the PV inverter.Both the load fluctuation and loss of the SOP were considered.Three multi-objective optimization algorithms were used,and a compromise optimal solution was calculated.Case studies were conducted using an IEEE 33-node system.The simulation results indicated that the SOP and PVs complemented each other in terms of active power transmission and reactive power compensation.Synergetic optimization improves power control capability and flexibility,providing better power quality and PV consumption rate.
基金Science and Technology Development Fund of Wuhan Institute of Earth Observation,China Earthquake Administration(No.302021-21)Open Fund of Wuhan,Gravitation and Solid Earth Tides,National Observation and Research Station(WHYWZ202218).
文摘On February 6,2023,a devastating earthquake with a moment magnitude of M_(W)7.8 struck the town of Pazarcik in south-central Türkiye,followed by another powerful earthquake with a moment magnitude of M_(W)7.6 that struck the nearby city of Elbistan 9 h later.To study the characteristics of surface deformation caused by this event and the influence of fault rupture,this study calculated the static coseismic deformation of 56 stations and dynamic displacement waveforms of 15 stations using data from the Turkish national fixed global navigation satellite system(GNSS)network.A maximum static coseismic displacement of 0.38 m for the M_(W)7.8 Kahramanmaras earthquake was observed at station ANTE,36 km from the epicenter,and a maximum dynamic coseismic displacement of 4.4 m for the M_(W)7.6 Elbistan earthquake was observed at station EKZ1,5 km from the epicenter.The rupture-slip distributions of the two earthquakes were inverted using GNSS coseismic deformation as a constraint.The results showed that the Kahramanmaras earthquake rupture segment was distinct and exposed on the ground,resulting in significant rupture slip along the Amanos and Pazarcik fault segments of the East Anatolian Fault.The maximum slip in the Pazarcik fault segment was 10.7 m,and rupture occurred at depths of 0–15 km.In the Cardak fault region,the Elbistan earthquake caused significant ruptures at depths of 0–12 km,with the largest amount of slip reaching 11.6 m.The Coulomb stress change caused by the Kahramanmaras earthquake rupture along the Cardak fault segment was approximately 2 bars,and the area of increased Coulomb stress corresponded to the subsequent rupture region of the M_(W)7.6 earthquake.Thus,it is likely that the M_(W)7.8 earthquake triggered or promoted the M_(W)7.6 earthquake.Based on the cumulative stress impact of the M_(W)7.8 and M_(W)7.6 events,the southwestern segment of the East Anatolian Fault,specifically the Amanos fault segment,experienced a Coulomb rupture stress change exceeding 2 bars,warranting further attention to assess its future seismic hazard risk.
基金supported by the National Natural Science Foundation of China(32070423)Third Xinjiang Scientific Expedition Program(2021xjkk0600)。
文摘DEAR EDITOR,Biogeography is a scientific field dedicated to the investigation of the origins and distribution patterns of organisms,as well as predicting future alterations in their geographical distributions(Cox&Moore,2005).However,the majority of conclusions drawn within the field of biogeography are hypothetical.Rigorous testing of these biogeographic hypotheses remains a considerable challenge.This paper presents the concept of“integrative biogeography”,which emphasizes the experimental testing of biogeographic hypotheses through studies on geological history,as well as biotic and abiotic factors(Figure 1).
基金supported by the grant RTI2018-095925-A-100,“Interactions among soil microorganisms as a tool for the sustainability of the resistance of rootstocks fruit trees against plant-parasitic nematodes”funded by Ministry of Science and Innovation(MCIN)and by European Regional Development Fund(ERDF)“A way of making Europe”The first author is a recipient of grant(PRE2019-090206)funded by European Social Fund(ESF)“Investing in your future”。
文摘A wide survey was conducted to study plant-parasitic nematodes(PPNs)associated with Prunus groves in Spain.This research aimed to determine the prevalence and distribution of PPNs in Prunus groves,as well as the influence of explanatory variables describing soil,climate and agricultural management in structuring the variation of PPNs community composition.A total of 218 sampling sites were surveyed and 84 PPN species belonging to 32 genera were identified based of an integrative taxonomic approach.PPN species considered as potential limiting factors in Prunus production,such as Meloidogyne arenaria,M.incognita,M.javanica,Pratylenchus penetrans and P.vulnus,were identified in this survey.Seven soil physico-chemical(C,Mg,N,Na,OM,P,pH and clay,loamy sand and sandy loam texture classes),four climate(Bio04,Bio05,Bio13 and Bio14)and four agricultural management variables(grove-use history less than 10 years,irrigation,apricot seedling rootstock,and Montclar rootstock)were identified as the most influential variables driving spatial patterns of PPNs communities.In particular,younger plantations showed higher values for species richness and diversity indices than groves cultivated for more than 20 years with Prunus spp.Our study increases the knowledge of the distribution and prevalence of PPNs associated with Prunus rhizosphere,as well as on the influence of explanatory variables driving the spatial structure PPNs communities,which has important implications for the successful design of sustainable management strategies in the future in this agricultural system.
基金funded by the Faculty of Geography under the scheme of“Dana Hibah Penelitian Mandiri Dosen Tahun 2023 Tahap 1”。
文摘Ten rock samples consisting of one pyroclastic density current(PDC1)deposit,seven lava flows(LF1–7),and two summit lava domes(LD1,2)were studied to understand the petrogenesis and magma dynamics at Mt.Sumbing.The stratigraphy is arranged as LF1,PDC1,LF2,LF3,LF4,LF5,LF6,LF7,LD1,and LD2;furthermore,these rocks were divided into two types.TypeⅠ,observed in the oldest(LF1)sample,has poor MgO and high Ba/Nb,Th/Yb and Sr.The remaining samples(PDC1–LD2)represent typeⅡ,characterized by high MgO and low Ba/Nb,Th/Yb and Sr values.We suggest that type I is derived from AOC(altered oceanic crust)-rich melts that underwent significant crustal assimilation,while typeⅡoriginates from mantle-rich melts with less significant crustal assimilation.The early stage of typeⅡmagma(PDC1–LF3)was considered a closed system,evolving basaltic andesite into andesite(55.0–60.2 wt%SiO_(2))with a progressively increasing phenocryst(0.30–0.48φ_(PC))and decreasing crystal size distribution(CSD)slope(from-3.9 to-2.9).The evidence of fluctuating silica and phenocryst contents(between 55.9–59.7 wt%and 0.25–0.41φ_(PC),respectively),coupled with the kinked and steep(from-5.0 to-3.3)CSD curves imply the interchanging condition between open(i.e.,magma mixing)and closed magmatic systems during the middle stage(LF4–LF6).Finally,it underwent to closed system again during the final stage(LF7–LD2)because the magma reached dacitic composition(at most 68.9 wt%SiO_(2))with abundant phenocryst(0.38–0.45φ_(PC))and gentle CSD slope(from-4.1 to-1.2).
基金the National Natural Science Foundation of China(32071955)the Natural Science Foundation of Shaanxi Province,China(2018JQ3061).
文摘Lodging is still the key factor that limits continuous increases in wheat yields today,because the mechanical strength of culms is reduced due to low-light stress in populations under high-yield cultivation.The mechanical properties of the culm are mainly determined by lignin,which is affected by the light environment.However,little is known about whether the light environment can be sufficiently improved by changing the population distribution to inhibit culm lodging.Therefore,in this study,we used the wheat cultivar“Xinong 979”to establish a low-density homogeneous distribution treatment(LD),high-density homogeneous distribution treatment(HD),and high-density heterogeneous distribution treatment(HD-h)to study the regulatory effects and mechanism responsible for differences in the lodging resistance of wheat culms under different population distributions.Compared with LD,HD significantly reduced the light transmittance in the middle and basal layers of the canopy,the net photosynthetic rate in the middle and lower leaves of plants,the accumulation of lignin in the culm,and the breaking resistance of the culm,and thus the lodging index values increased significantly,with lodging rates of 67.5%in 2020–2021 and 59.3%in 2021–2022.Under HD-h,the light transmittance and other indicators in the middle and basal canopy layers were significantly higher than those under HD,and the lodging index decreased to the point that no lodging occurred.Compared with LD,the activities of phenylalanine ammonia-Lyase(PAL),4-coumarate:coenzyme A ligase(4CL),catechol-O-methyltransferase(COMT),and cinnamyl-alcohol dehydrogenase(CAD)in the lignin synthesis pathway were significantly reduced in the culms under HD during the critical period for culm formation,and the relative expression levels of TaPAL,Ta4CL,TaCOMT,and TaCAD were significantly downregulated.However,the activities of lignin synthesis-related enzymes and their gene expression levels were significantly increased under HD-h compared with HD.A partial least squares path modeling analysis found significant positive effects between the canopy light environment,the photosynthetic capacity of the middle and lower leaves of plants,lignin synthesis and accumulation,and lodging resistance in the culms.Thus,under conventional high-density planting,the risk of wheat lodging was significantly higher.Accordingly,the canopy light environment can be optimized by changing the heterogeneity of the population distribution to improve the photosynthetic capacity of the middle and lower leaves of plants,promote lignin accumulation in the culm,and enhance lodging resistance in wheat.These findings provide a basis for understanding the mechanism responsible for the lower mechanical strength of the culm under high-yield wheat cultivation,and a theoretical basis and for developing technical measures to enhance lodging resistance.
文摘The secure and normal operation of distributed networks is crucial for accurate parameter estimation.However,distributed networks are frequently susceptible to Byzantine attacks.Considering real-life scenarios,this paper investigates a probability Byzantine(PB)attack,utilizing a Bernoulli distribution to simulate the attack probability.Historically,additional detection mechanisms are used to mitigate such attacks,leading to increased energy consumption and burdens on distributed nodes,consequently diminishing operational efficiency.Differing from these approaches,an adaptive updating distributed estimation algorithm is proposed to mitigate the impact of PB attacks.In the proposed algorithm,a penalty strategy is initially incorporated during data updates to weaken the influence of the attack.Subsequently,an adaptive fusion weight is employed during data fusion to merge the estimations.Additionally,the reason why this penalty term weakens the attack has been analyzed,and the performance of the proposed algorithm is validated through simulation experiments.
基金gratefully acknowledge the financial support from the National Natural Science Foundation of China(No.U20A20270)China Postdoctoral Science Foundation(No.2022M722486).We would like to thank Dr.Wei Yuan at the Analytical&Testing Center of Wuhan University of Science and Technology for the help on EPMA analyses.
文摘The elemental distribution and microstructure near the surface of high-Mn/Al austenitic low-density steel were investigated after isothermal holding at temperatures of 900-1200℃ in different atmospheres,including air,N_(2),and N_(2)+CO_(2).No ferrite was formed near the surface of the experimental steel during isothermal holding at 900 and 1000℃ in air,while ferrite was formed near the steel sur-face at holding temperatures of 1100 and 1200℃.The ferrite fraction was larger at 1200℃ because more C and Mn diffused to the sur-face,exuded from the steel,and then reacted with N and O to form oxidation products.The thickness of the compound scale increased owing to the higher diffusion rate at higher temperatures.In addition,after isothermal holding at 1100℃ in N_(2),the Al content near the surface slightly decreased,while the C and Mn contents did not change.Therefore,no ferrite was formed near the surface.However,the near-surface C and Al contents decreased after holding at 1100℃in the N_(2)+CO_(2)mixed atmosphere,resulting in the formation of a small amount of ferrite.The compound scale was thickest in N_(2),followed by the N_(2)+CO_(2)mixed atmosphere,and thinnest in air.Overall,the element loss and ferrite fraction were largest after holding in air at the same temperature.The differences in element loss and ferrite frac-tion between in N_(2) and N_(2)+CO_(2)atmospheres were small,but the compound scale formed in N_(2) was significantly thicker.According to these results,N_(2)+CO_(2)is the ideal heating atmosphere for the industrial production of high-Mn/Al austenitic low-density steel.
基金the supports from National Natural Science Foundation of China(61988101,62073142,22178103)National Natural Science Fund for Distinguished Young Scholars(61925305)International(Regional)Cooperation and Exchange Project(61720106008)。
文摘Crude oil scheduling optimization is an effective method to enhance the economic benefits of oil refining.But uncertainties,including uncertain demands of crude distillation units(CDUs),might make the production plans made by the traditional deterministic optimization models infeasible.A data-driven Wasserstein distributionally robust chance-constrained(WDRCC)optimization approach is proposed in this paper to deal with demand uncertainty in crude oil scheduling.First,a new deterministic crude oil scheduling optimization model is developed as the basis of this approach.The Wasserstein distance is then used to build ambiguity sets from historical data to describe the possible realizations of probability distributions of uncertain demands.A cross-validation method is advanced to choose suitable radii for these ambiguity sets.The deterministic model is reformulated as a WDRCC optimization model for crude oil scheduling to guarantee the demand constraints hold with a desired high probability even in the worst situation in ambiguity sets.The proposed WDRCC model is transferred into an equivalent conditional value-at-risk representation and further derived as a mixed-integer nonlinear programming counterpart.Industrial case studies from a real-world refinery are conducted to show the effectiveness of the proposed method.Out-of-sample tests demonstrate that the solution of the WDRCC model is more robust than those of the deterministic model and the chance-constrained model.
基金This research was supported by the Tianfu Yongxing Laboratory Organized Research Project Funding(2023KJGG05)the Geological Survey Project of Xinjiang Uygur Autonomous Region Geology and Mineral Exploration and Development Bureau(XGMB202356).
文摘The Hotan Prefecture of Xinjiang Uygur Autonomous Region,China belongs to arid desert climate,with significant soil salinization issues.The study selected six rivers in Hotan Prefecture(Pishan,Qaraqash,Yurungqash,Celle,Kriya,and Niya rivers)to explore the spatial distribution of soil salinization in this area and its underlying mechanisms.Sampling was conducted along each river's watershed,from the Gobi in the upper reaches,through the anthropogenic impact area in the middle reaches,to the desert area in the lower reaches.Soil physical-chemical indicators,including total soluble salts,pH,K+,Na+,Ca2+,Mg2+,SO42-,Cl-,CO32-,HCO3-,organic matter,available nitrogen,available phosphorus,and available potassium,were tested,along with the total dissolved solids of surface water and groundwater.The results revealed that the soil water and nutrient contents in anthropogenic impact area were higher than those in Gobi and desert areas,while the pH and total soluble salts were lower than those in Gobi and desert areas.The ions in the soil of the study area were primarily Cl-,SO42-,K+,and Na+,and the ion concentration of soil salt were positively correlated with surface water and groundwater.Overall,the study area exhibited low soil water content,low clay content,infertile soil,and high soil salinization,dominated by weak to moderate chloride-sulfate types.Compared with Gobi and desert areas,the soil in anthropogenic impact area had higher soil water content,lower pH,lower soluble salts,and higher nutrients,indicating that human farming activities help mitigate salinization.These findings have practical implications for guiding the scientific prevention and control of soil salinization in the arid areas and for promoting sustainable agricultural development.
基金supported by National Natural Science Foundation of China[grant number U21A20399]Liaoning Revitalization Talents Program[grant number XLYC1802059]+2 种基金the Key R&D Program of Liaoning Province[grant number2019JH2/10300044]the Key Laboratory Program of Liaoning Province[grant number 2018225113]the Key Laboratory Program of Shenyang City[grant number 21-103-0-16]。
文摘Objective Tissue uptake and distribution of nano-/microplastics was studied at a single high dose by gavage in vivo.Methods Fluorescent microspheres(100 nm,3μm,and 10μm)were given once at a dose of 200 mg/(kg∙body weight).The fluorescence intensity(FI)in observed organs was measured using the IVIS Spectrum at 0.5,1,2,and 4 h after administration.Histopathology was performed to corroborate these findings.Results In the 100 nm group,the FI of the stomach and small intestine were highest at 0.5 h,and the FI of the large intestine,excrement,lung,kidney,liver,and skeletal muscles were highest at 4 h compared with the control group(P<0.05).In the 3μm group,the FI only increased in the lung at 2 h(P<0.05).In the 10μm group,the FI increased in the large intestine and excrement at 2 h,and in the kidney at 4 h(P<0.05).The presence of nano-/microplastics in tissues was further verified by histopathology.The peak time of nanoplastic absorption in blood was confirmed.Conclusion Nanoplastics translocated rapidly to observed organs/tissues through blood circulation;however,only small amounts of MPs could penetrate the organs.
基金partially supported by the Open Project Program from the Key Laboratory of South Subtropical Fruit Biology and Genetic Resource Utilization(Ministry of Agriculture and Rural Affairs),China(212103)。
文摘Vegetable fields are often contaminated by heavy metals,and Spodoptera exigua is a major vegetable pest which is stressed by heavy metals mainly by feeding.In this study,cadmium accumulation in the tissues of S.exigua exposed to cadmium and its effects on the growth and development of the parents and the offspring were investigated.Under the stress of different concentrations of cadmium(0.2,3.2,and 51.2 mg kg^(-1)),the cadmium content in each tissue of S.exigua increased in a dose-dependent manner.At the larval stage,the highest cadmium accumulation was found in midgut in all three cadmium treatments,but at the adult stage,the highest cadmium content was found in fat body.In addition,the cadmium content in ovaries was much higher than in testes.When F1S.exigua was stressed by cadmium and the F_(2)generation was not fed a cadmium-containing diet,the larval survival,pupation rate,emergence rate and fecundity of the F_(2)generation were significantly reduced in the 51.2 mg kg^(-1)treatment compared to the corresponding F1generation.Even in the F_(2)generation of the 3.2 mg kg^(-1)treatment,the fecundity was significantly lower than in the parental generation.The fecundity of the only-female stressed treatment was significantly lower than that of the only-male stressed treatment at the 3.2 and 51.2 mg kg^(-1)cadmium exposure levels.When only mothers were stressed at the larval stage,the fecundity of the F_(2)generation was significantly lower than that of the F1generation in the 51.2 mg kg^(-1)treatment,and it was also significantly lower than in the 3.2 and 0.2 mg kg^(-1)treatments.The results of our study can provide useful information for forecasting the population increase trends under different heavy metal stress conditions and for the reliable environmental risk assessment of heavy metal pollution.
基金supported by the Chinese National General Program of the National Natural Science Foundation of China,No.82072162(to XY)。
文摘Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneuro ns.Howeve r,current research on the spatial location of the spinal motoneurons innervating differe nt muscles is limited.In this study,we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs,which were innervated by the obturator nerve,femoral nerve,inferior gluteal nerve,deep pe roneal nerve,and tibial nerve.Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared o rgans(3DISCO)and 3-D imaging technology based on lightsheet fluorescence microscopy(LSFM).Additionally,we propose the hypothesis that"messenger zones"exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups.We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons.Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse.Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles,but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.
基金financially supported by the National Key R&D Program of China(No.2022YFC3104205)the National Natural Science Foundation of China(No.42377457).
文摘The generation and propagation mechanism of strong nonlinear waves in the South China Sea is an essential research area. In this study, the third-generation wave model WAVEWATCH Ⅲ is employed to simulate wave fields under extreme sea states. The model, integrating the ST6 source term, is validated against observed data, demonstrating its credibility. The spatial distribution of the occurrence probability of strong nonlinear waves during typhoons is shown, and the waves in the straits and the northeastern part of the South China Sea show strong nonlinear characteristics. The high-order spectral model HOS-ocean is employed to simulate the random wave surface series beneath five different platform areas. The waves during the typhoon exhibit strong nonlinear characteristics, and freak waves exist. The space-varying probability model is established to describe the short-term probability distribution of nonlinear wave series. The exceedance probability distributions of the wave surface beneath different platform areas are compared and analyzed. The results show that with an increase in the platform area, the probability of a strong nonlinear wave beneath the platform increases.
