Smoothed cepstral peak prominence(CPPs)is a measurement of the distance from the prominent cepstral peak to the linear regression line directly beneath it.Variations of CPPs data acquisition and analysis lead to the c...Smoothed cepstral peak prominence(CPPs)is a measurement of the distance from the prominent cepstral peak to the linear regression line directly beneath it.Variations of CPPs data acquisition and analysis lead to the complexity of the clinical cut-off values,and there are no agreeable values for a specific voice disorder,such as hypokinetic dysarthria associated with Parkinson’s disease(PD).This study examined the CPPs in people with hypokinetic dysarthria associated with PD compared with healthy participants.Results demonstrated significant differences in speech tasks of sustained vowel and connected speech,with CPPs of connected speech more sensitive to dysphonia and gender difference in PD participants.Males in PD participants presented higher CPPs for sustained vowels and lower CPPs for connected speech than females.It is implied that a consistent clinical application protocol is necessary,and multiple acoustic measures are needed to ensure the accuracy of clinical decisions.展开更多
BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation be...BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation between the clinical efficacy of low-frequency electrical stimulation combined with tri-tongue acupuncture in patients with post-stroke dysarthria.AIM To investigate the clinical effects of tri-tongue acupuncture combined with lowfrequency electrical stimulation for treating post-stroke dysarthria.METHODS Ninety patients with post-stroke dysarthria,who were admitted to our hospital from December 2019 to June 2021,were selected and equally divided into two groups(n=45/group)according to the random number table method.Tri-tongue acupuncture was administered in the control group.The treatment group received both tri-tongue acupuncture and low-frequency electrical stimulation.The clinical efficacy,Western Aphasia Battery(WAB)score,general quality of life inventory(GQOLI-74)score,Frenchay Dysarthria Assessment score,and speech function grades were compared and analyzed between both groups.RESULTS The overall efficacy in the treatment group was better than that in the control group(P<0.05).Before treatment,the WAB,Frenchay Dysarthria Assessment,or GQOLI-74 scores(P>0.05)did not differ between the groups.After therapy,the WAB,Frenchay Dysarthria Assessment,and GQOLI-74 scores in both groups increased significantly(P<0.05),and the treatment group exhibited a significantly greater increase than that of the controls(P<0.05).Moreover,the classification of speech function did not differ between the two groups before treatment(P>0.05),whereas significant improvements were observed in both groups after treatment(P<0.05).The degree of improvement in the treatment group was greater than that in the control group(P<0.05).CONCLUSION Low-frequency electrical stimulation,in conjunction with tri-tongue acupuncture,exhibits a good clinical effect on post-stroke dysarthria.展开更多
Distinguishing stroke mimics constitutes a considerable challenge for clinicians in emergency department. Here, we illustrate an extremely rare patient presenting with acute onset isolated dysarthria, who finally rece...Distinguishing stroke mimics constitutes a considerable challenge for clinicians in emergency department. Here, we illustrate an extremely rare patient presenting with acute onset isolated dysarthria, who finally received diagnosis of tardive phenomenon associated with betahistine. Through the presentation of this case, we point out tardive phenomenon as an alternative differential diagnosis of stroke. Furthermore, this case adds substantial data presenting an interesting manifestation of isolated dysarthria as a tardive phenomenon, occurring due to betahistine usage which is extremely rare in literature.展开更多
This article reports a case of dysarthria which was successfully treated by Strannik Light Therapy (SLT). It briefly discusses the known etiology for the condition and illustrates that dysarthria must be a problem of ...This article reports a case of dysarthria which was successfully treated by Strannik Light Therapy (SLT). It briefly discusses the known etiology for the condition and illustrates that dysarthria must be a problem of autonomic dysfunction in which pathological changes can influence the structure and/or subsequent function of the dynamic interplay between the brain and the organs involving the autonomic nervous system and physiological systems. The author reports a particular case in which a patient undertaking SLT fully recovered the ability to speak within 6 days.展开更多
This report describes the case of a patient with dysarthria during the administration of the third cycle of Folfu＇i for the treatment of metastatic colon cancer. After a thorough neurological examination and neuroima...This report describes the case of a patient with dysarthria during the administration of the third cycle of Folfu＇i for the treatment of metastatic colon cancer. After a thorough neurological examination and neuroimaging, structural causes were excluded and thus the dysarthria was attributed to the irinotecan infusion. A slowing down of the infusion rate to 180 min during the 15 subsequent cycles led to the cessation of the episodes of dysarthria. In 2016, it was estimated there will be 134,490 new cases of colorectal cancer with a five-year survival rate of 21% among patients with metastatic disease. As Irinotecan is often part of the therapeutic regimen in such cases, both in the first and second-line setting, there is a need to report rare adverse outcomes in order to fmd out ways to better manage of these events. The mechanism by which Irinotecan causes dysarthria is unknown and further research in this area is warranted.展开更多
Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation g...Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation group （30 cases） was treated with speech therapy and acupuncture at major acupoints Lianquan （廉泉 CV 23）, Jinjin （金津 EX-HN 12）, Yuye （玉夜 EX-HN 13）, Fengchi（风池 GB 20）, Yifeng （翳风 TE 17） and Wangu（完骨 GB 12）, and the control group （31 cases） was treated with speech therapy only. The changes of speech and acoustical indices were evaluated after 9 weeks treatment. Results The word articulation and the correct rate of writings in the two groups were significantly increased after treatment （both P〈0.01）. The total effective rate of 96.7%（29/30） in the observation group was superior to that of 67.7%（21/31） in the control group （P〈0.01）. The maximum phonation time （MPT） tested by a phonolaryngeal aeromechanical analyzer was significantly prolonged in both the observation group （12 cases） and the control group （11 cases） （both P〈0.01）, the improvement in the observation group being more obvious （P〈0.01）. Conclusion Acupuncture combined with speech therapy can improve the speech and acoustic level in the patient of dysarthria.展开更多
目的探讨神经性言语障碍患者单、复韵母构音运动的声学特征。方法在上海市多家医院收集24例40~81岁的神经性言语障碍患者(患者组),在上海市社区收集24例40~80岁的健康成人(对照组),从两组跟读含有不同韵母的语音样本中,提取单韵母/a/、...目的探讨神经性言语障碍患者单、复韵母构音运动的声学特征。方法在上海市多家医院收集24例40~81岁的神经性言语障碍患者(患者组),在上海市社区收集24例40~80岁的健康成人(对照组),从两组跟读含有不同韵母的语音样本中,提取单韵母/a/、/i/、/u/的第一、二共振峰(F1、F2),并计算出下颌距、舌距、元音空间面积(vowel space area,VSA)、元音清晰度指数(vowel articulation index,VAI);提取复韵母/ai/、/ua/、/uai/的第二共振峰并计算其斜率,比较不同语料任务下两组受试者的声学指标。结果单韵母任务下,患者组/a/的F1、/i/的F2、下颌距、舌距、VSA、VAI极显著小于正常对照组(P<0.01),/u/的F2极显著大于正常对照组(P<0.01);复韵母任务下,患者组/ai/、/ua/、/uai/的F2斜率均显著小于正常对照组(P<0.05)。结论神经性言语障碍患者单韵母构音运动范围减小,运动位置呈现集中趋势;复韵母构音运动速度减慢。展开更多
文摘Smoothed cepstral peak prominence(CPPs)is a measurement of the distance from the prominent cepstral peak to the linear regression line directly beneath it.Variations of CPPs data acquisition and analysis lead to the complexity of the clinical cut-off values,and there are no agreeable values for a specific voice disorder,such as hypokinetic dysarthria associated with Parkinson’s disease(PD).This study examined the CPPs in people with hypokinetic dysarthria associated with PD compared with healthy participants.Results demonstrated significant differences in speech tasks of sustained vowel and connected speech,with CPPs of connected speech more sensitive to dysphonia and gender difference in PD participants.Males in PD participants presented higher CPPs for sustained vowels and lower CPPs for connected speech than females.It is implied that a consistent clinical application protocol is necessary,and multiple acoustic measures are needed to ensure the accuracy of clinical decisions.
文摘BACKGROUND Few studies have investigated low-frequency electrical stimulation combined with tri-tongue acupuncture for the treatment of post-stroke dysarthria.This randomized clinical study assessed the correlation between the clinical efficacy of low-frequency electrical stimulation combined with tri-tongue acupuncture in patients with post-stroke dysarthria.AIM To investigate the clinical effects of tri-tongue acupuncture combined with lowfrequency electrical stimulation for treating post-stroke dysarthria.METHODS Ninety patients with post-stroke dysarthria,who were admitted to our hospital from December 2019 to June 2021,were selected and equally divided into two groups(n=45/group)according to the random number table method.Tri-tongue acupuncture was administered in the control group.The treatment group received both tri-tongue acupuncture and low-frequency electrical stimulation.The clinical efficacy,Western Aphasia Battery(WAB)score,general quality of life inventory(GQOLI-74)score,Frenchay Dysarthria Assessment score,and speech function grades were compared and analyzed between both groups.RESULTS The overall efficacy in the treatment group was better than that in the control group(P<0.05).Before treatment,the WAB,Frenchay Dysarthria Assessment,or GQOLI-74 scores(P>0.05)did not differ between the groups.After therapy,the WAB,Frenchay Dysarthria Assessment,and GQOLI-74 scores in both groups increased significantly(P<0.05),and the treatment group exhibited a significantly greater increase than that of the controls(P<0.05).Moreover,the classification of speech function did not differ between the two groups before treatment(P>0.05),whereas significant improvements were observed in both groups after treatment(P<0.05).The degree of improvement in the treatment group was greater than that in the control group(P<0.05).CONCLUSION Low-frequency electrical stimulation,in conjunction with tri-tongue acupuncture,exhibits a good clinical effect on post-stroke dysarthria.
文摘Distinguishing stroke mimics constitutes a considerable challenge for clinicians in emergency department. Here, we illustrate an extremely rare patient presenting with acute onset isolated dysarthria, who finally received diagnosis of tardive phenomenon associated with betahistine. Through the presentation of this case, we point out tardive phenomenon as an alternative differential diagnosis of stroke. Furthermore, this case adds substantial data presenting an interesting manifestation of isolated dysarthria as a tardive phenomenon, occurring due to betahistine usage which is extremely rare in literature.
文摘This article reports a case of dysarthria which was successfully treated by Strannik Light Therapy (SLT). It briefly discusses the known etiology for the condition and illustrates that dysarthria must be a problem of autonomic dysfunction in which pathological changes can influence the structure and/or subsequent function of the dynamic interplay between the brain and the organs involving the autonomic nervous system and physiological systems. The author reports a particular case in which a patient undertaking SLT fully recovered the ability to speak within 6 days.
文摘This report describes the case of a patient with dysarthria during the administration of the third cycle of Folfu＇i for the treatment of metastatic colon cancer. After a thorough neurological examination and neuroimaging, structural causes were excluded and thus the dysarthria was attributed to the irinotecan infusion. A slowing down of the infusion rate to 180 min during the 15 subsequent cycles led to the cessation of the episodes of dysarthria. In 2016, it was estimated there will be 134,490 new cases of colorectal cancer with a five-year survival rate of 21% among patients with metastatic disease. As Irinotecan is often part of the therapeutic regimen in such cases, both in the first and second-line setting, there is a need to report rare adverse outcomes in order to fmd out ways to better manage of these events. The mechanism by which Irinotecan causes dysarthria is unknown and further research in this area is warranted.
基金Supported by Scientific Research Project of China Rehabilitation Research Center:2006-23
文摘Objective To observe the effect of acupuncture combined with speech therapy on dysarthria after stroke or cerebral trauma. Methods Sixty-one cases of dysarthria were randomly divided into two groups. The observation group （30 cases） was treated with speech therapy and acupuncture at major acupoints Lianquan （廉泉 CV 23）, Jinjin （金津 EX-HN 12）, Yuye （玉夜 EX-HN 13）, Fengchi（风池 GB 20）, Yifeng （翳风 TE 17） and Wangu（完骨 GB 12）, and the control group （31 cases） was treated with speech therapy only. The changes of speech and acoustical indices were evaluated after 9 weeks treatment. Results The word articulation and the correct rate of writings in the two groups were significantly increased after treatment （both P〈0.01）. The total effective rate of 96.7%（29/30） in the observation group was superior to that of 67.7%（21/31） in the control group （P〈0.01）. The maximum phonation time （MPT） tested by a phonolaryngeal aeromechanical analyzer was significantly prolonged in both the observation group （12 cases） and the control group （11 cases） （both P〈0.01）, the improvement in the observation group being more obvious （P〈0.01）. Conclusion Acupuncture combined with speech therapy can improve the speech and acoustic level in the patient of dysarthria.
文摘目的探讨神经性言语障碍患者单、复韵母构音运动的声学特征。方法在上海市多家医院收集24例40~81岁的神经性言语障碍患者(患者组),在上海市社区收集24例40~80岁的健康成人(对照组),从两组跟读含有不同韵母的语音样本中,提取单韵母/a/、/i/、/u/的第一、二共振峰(F1、F2),并计算出下颌距、舌距、元音空间面积(vowel space area,VSA)、元音清晰度指数(vowel articulation index,VAI);提取复韵母/ai/、/ua/、/uai/的第二共振峰并计算其斜率,比较不同语料任务下两组受试者的声学指标。结果单韵母任务下,患者组/a/的F1、/i/的F2、下颌距、舌距、VSA、VAI极显著小于正常对照组(P<0.01),/u/的F2极显著大于正常对照组(P<0.01);复韵母任务下,患者组/ai/、/ua/、/uai/的F2斜率均显著小于正常对照组(P<0.05)。结论神经性言语障碍患者单韵母构音运动范围减小,运动位置呈现集中趋势;复韵母构音运动速度减慢。
