Recently,electronic skins and fl exible wearable devices have been developed for widespread applications in medical monitoring,artifi cial intelligence,human–machine interaction,and artifi cial prosthetics.Flexible p...Recently,electronic skins and fl exible wearable devices have been developed for widespread applications in medical monitoring,artifi cial intelligence,human–machine interaction,and artifi cial prosthetics.Flexible proximity sensors can accurately perceive external objects without contact,introducing a new way to achieve an ultrasensitive perception of objects.This article reviews the progress of fl exible capacitive proximity sensors,fl exible triboelectric proximity sensors,and fl exible gate-enhanced proximity sensors,focusing on their applications in the electronic skin fi eld.Herein,their working mechanism,materials,preparation methods,and research progress are discussed in detail.Finally,we summarize the future challenges in developing fl exible proximity sensors.展开更多
Electronic skins can monitor minute physiological signal variations in the human skins and represent the body’s state,showing an emerging trend for alternative medical diagnostics and human-machine interfaces.In this...Electronic skins can monitor minute physiological signal variations in the human skins and represent the body’s state,showing an emerging trend for alternative medical diagnostics and human-machine interfaces.In this study,we designed a bioinspired directional moisture-wicking electronic skin(DMWES)based on the construction of heterogeneous fibrous membranes and the conductive MXene/CNTs electrospraying layer.Unidirectional moisture transfer was successfully realized by surface energy gradient and push-pull effect via the design of distinct hydrophobic-hydrophilic difference,which can spontaneously absorb sweat from the skin.The DMWES membrane showed excellent comprehensive pressure sensing performance,high sensitivity(maximum sensitivity of 548.09 kPa^(−1)),wide linear range,rapid response and recovery time.In addition,the single-electrode triboelectric nanogenerator based on the DMWES can deliver a high areal power density of 21.6μW m^(−2) and good cycling stability in high pressure energy harvesting.Moreover,the superior pressure sensing and triboelectric performance enabled the DMWES for all-range healthcare sensing,including accurate pulse monitoring,voice recognition,and gait recognition.This work will help to boost the development of the next-generation breathable electronic skins in the applications of AI,human-machine interaction,and soft robots.展开更多
Transparent, flexible electronic skin holds a wide range of applications in robotics, humanmachine interfaces, artificial intelligence, prosthetics, and health monitoring. Silver nanowire are mechanically flexible and...Transparent, flexible electronic skin holds a wide range of applications in robotics, humanmachine interfaces, artificial intelligence, prosthetics, and health monitoring. Silver nanowire are mechanically flexible and robust, which exhibit great potential in transparent and electricconducting thin film. Herein, we report on a silver-nanowire spray-coating and electrodemicrostructure replicating strategy to construct a transparent, flexible, and sensitive electronic skin device. The electronic skin device shows highly sensitive piezo-capacitance response to pressure. It is found that micropatterning the surface of dielectric layer polyurethane elastomer by replicating from microstructures of natural-existing surfaces such as lotus leaf, silk, and frosted glass can greatly enhance the piezo-capacitance performance of the device. The microstructured pressure sensors based on silver nanowire exhibit good transparency, excellent flexibility, wide pressure detection range (0-150 kPa), and high sensitivity (1.28 kPa-1).展开更多
User-interactive electronic skin(e-skin) that could convert mechanical stimuli into distinguishable outputs displays tremendous potential for wearable devices and health care applications. However, the existing device...User-interactive electronic skin(e-skin) that could convert mechanical stimuli into distinguishable outputs displays tremendous potential for wearable devices and health care applications. However, the existing devices have the disadvantages such as complex integration procedure and lack of the intuitive signal display function. Here, we present a bioinspired user-interactive e-skin, which is simple in structure and can synchronously achieve digital electrical response and optical visualization upon external mechanical stimulus. The e-skin comprises a conductive layer with a carbon nanotubes/cellulose nanofibers/MXene nanohybrid network featuring remarkable electromechanical behaviors, and a stretchable elastomer layer, which is composed of silicone rubber and thermochromic pigments. Furthermore, the conductive nanohybrid network with outstanding Joule heating performance can generate controllable thermal energy under voltage input and then achieve the dynamic coloration of silicone-based elastomer. Especially, such an innovative fusion strategy of digital data and visual images enables the e-skin to monitor human activities with evermore intuition and accuracy. The simple design philosophy and reliable operation of the demonstrated e-skin are expected to provide an ideal platform for next-generation flexible electronics.展开更多
There is growing recognition that the developments in piezoresistive devices from personal healthcare to artificial intelli-gence,will emerge as de novo translational success in electronic skin.Here,we review the upda...There is growing recognition that the developments in piezoresistive devices from personal healthcare to artificial intelli-gence,will emerge as de novo translational success in electronic skin.Here,we review the updates with regard to piezoresistive sensors including basic fundamentals,design and fabrication,and device performance.We also discuss the prosperous advances in piezoresistive sensor application,which offer perspectives for future electronic skin.展开更多
With the aging of society and the increase in people’s concern for personal health,long-term physiological signal monitoring in daily life is in demand.In recent years,electronic skin(e-skin)for daily health monitori...With the aging of society and the increase in people’s concern for personal health,long-term physiological signal monitoring in daily life is in demand.In recent years,electronic skin(e-skin)for daily health monitoring applications has achieved rapid development due to its advantages in high-quality physiological signals monitoring and suitability for system integrations.Among them,the breathable e-skin has developed rapidly in recent years because it adapts to the long-term and high-comfort wear requirements of monitoring physiological signals in daily life.In this review,the recent achievements of breathable e-skins for daily physiological monitoring are systematically introduced and discussed.By dividing them into breathable e-skin electrodes,breathable e-skin sensors,and breathable e-skin systems,we sort out their design ideas,manufacturing processes,performances,and applications and show their advantages in long-term physiological signal monitoring in daily life.In addition,the development directions and challenges of the breathable e-skin are discussed and prospected.展开更多
Neurological electronic skin(E-skin)can process and transmit information in a distributed manner that achieves effective stimuli perception,holding great promise in neuroprosthetics and soft robotics.Neurological E-sk...Neurological electronic skin(E-skin)can process and transmit information in a distributed manner that achieves effective stimuli perception,holding great promise in neuroprosthetics and soft robotics.Neurological E-skin with multifunctional perception abilities can enable robots to precisely interact with the complex surrounding environment.However,current neurological E-skins that possess tactile,thermal,and visual perception abilities are usually prepared with rigid materials,bringing difficulties in realizing biologically synapse-like softness.Here,we report a soft multifunctional neurological E-skin(SMNE)comprised of a poly(3-hexylthiophene)(P3HT)nanofiber polymer semiconductor-based stretchable synaptic transistor and multiple soft artificial sensory receptors,which is capable of effectively perceiving force,thermal,and light stimuli.The stretchable synaptic transistor can convert electrical signals into transient channel currents analogous to the biological excitatory postsynaptic currents.And it also possesses both short-term and long-term synaptic plasticity that mimics the human memory system.By integrating a stretchable triboelectric nanogenerator,a soft thermoelectric device,and an elastic photodetector as artificial receptors,we further developed an SMNE that enables the robot to make precise actions in response to various surrounding stimuli.Compared with traditional neurological E-skin,our SMNE can maintain the softness and adaptability of biological synapses while perceiving multiple stimuli including force,temperature,and light.This SMNE could promote the advancement of E-skins for intelligent robot applications.展开更多
Language barrier is the main cause of disagreement.Sign language,which is a common language in all the worldwide language families,is difficult to be entirely popularized due to the high cost of learning as well as th...Language barrier is the main cause of disagreement.Sign language,which is a common language in all the worldwide language families,is difficult to be entirely popularized due to the high cost of learning as well as the technical barrier in real-time translation.To solve these problems,here,we constructed a wearable organohydrogel-based electronic skin(e-skin)with fast self-healing,strong adhesion,extraor-dinary anti-freezing and moisturizing properties for sign language recognition under complex environ-ments.The e-skin was obtained by using an acrylic network as the main body,aluminum(III)and bay-berry tannin as the crosslinking agent,water/ethylene glycol as the solvent system,and a polyvinyl al-cohol network to optimize the network performance.Using this e-skin,a smart glove was further built,which could carry out the large-scale data collection of common gestures and sign languages.With the help of the deep learning method,specific recognition and translation for various gestures and sign lan-guages could be achieved.The accuracy was 93.5%,showing the ultra-high classification accuracy of a sign language interpreter.In short,by integrating multiple characteristics and combining deep learning technology with hydrogel materials,the e-skin achieved an important breakthrough in human-computer interaction and artificial intelligence,and provided a feasible strategy for solving the dilemma of mutual exclusion between flexible electronic devices and human bodies.展开更多
As a stretchable seamless device,electronic skin(E-skin)has drawn enormous interest due to its skin-like sensing capability.Besides the basic perception of force and temperature,multiple perception that is beyond exis...As a stretchable seamless device,electronic skin(E-skin)has drawn enormous interest due to its skin-like sensing capability.Besides the basic perception of force and temperature,multiple perception that is beyond existing functions of human skin is becoming an important direction for E-skin developments.However,the present E-skins for multiple perceptions mainly rely on different sensing materials and heterogeneous integration,resulting in a complex device structure.Additionally,their stretchability is usually achieved by the complicated microstructure design of rigid materials.Here,we report an intrinsically stretchable polymer semiconductor based E-skin with a simple structure for multiple perceptions of force,temperature,and visible light.The E-skin is on the basis of poly(3-hexylthiophene)(P3HT)nanofibers percolated polydimethylsiloxane(PDMS)composite polymer semiconductor,which is fabricated by a facile solution method.The E-skin shows reliable sensing capabilities when it is used to perceive strain,pressure,temperature,and visible light.Based on the E-skin,an intelligent robotic hand sensing and controlling system is further demonstrated.Compared with conventional E-skins for multiple perceptions,this E-skin only has a simple monolayer sensing membrane without the need of combining different sensing materials,heterogeneous integration,and complicated microstructure design.Such a strategy of utilizing intrinsically stretchable polymer semiconductor to create simple structured E-skin for multiple perceptions will promote the development of E-skins in a broad application scenario,such as artificial robotic skins,virtual reality,intelligent gloves,and biointegrated electronics.展开更多
Smart fibers are considered as promising materials for the fabrication of wearable electronic skins owing to their features such as superior flexibility,light weight,high specific area,and ease of modification.Besides...Smart fibers are considered as promising materials for the fabrication of wearable electronic skins owing to their features such as superior flexibility,light weight,high specific area,and ease of modification.Besides,piezoelectric or triboelectric electronic skins can respond to mechanical stimulation and directly convert the mechanical energy into electrical power for self-use,thereby providing an attractive method for tactile sensing and motion perception.The incorporation of sensing capabilities into smart fibers could be a powerful approach to the development of self-powered electronic skins.Herein,we review several aspects of the recent advancements in the development of self-powered electronic skins constructed with smart fibers.The summarized aspects include functional material selection,structural design,pressure sensing mechanism,and proof-to-concept demonstration to practical application.In particular,various fabrication strategies and a wide range of practical applications have been systematically introduced.Finally,a critical assessment of the challenges and promising perspectives for the development of fiber-based electronic skins has been presented.展开更多
Conformable and wire-less charging energy storage devices play important roles in enabling the fast development of wearable,non-contact soft electronics.However,current wire-less charging power sources are still restr...Conformable and wire-less charging energy storage devices play important roles in enabling the fast development of wearable,non-contact soft electronics.However,current wire-less charging power sources are still restricted by limited flexural angles and fragile connection of components,resulting in the failure expression of performance and constraining their fur-ther applications in health monitoring wearables and moveable artificial limbs.Herein,we present an ultracompatible skin-like integrated wireless charging micro-supercapacitor,which building blocks(including electrolyte,electrode and substrate)are all evaporated by liquid precursor.Owing to the infiltration and permeation of the liquid,each part of the integrated device attached firmly with each other,forming a compact and all-in-one configuration.In addition,benefitting from the controllable volume of electrode solution precursor,the electrode thickness is easily regulated varying from 11.7 to 112.5μm.This prepared thin IWC-MSC skin can fit well with curving human body,and could be wireless charged to store electricity into high capacitive micro-supercapacitors(11.39 F cm-3)of the integrated device.We believe this work will shed light on the construction of skin-attachable electronics and irregular sensing microrobots.展开更多
Recently,polymer materials have been at the forefront of other materials in building high-performance flexible electronic skin(e-skin)devices due to con-spicuous advantages including excellent mechanical flexibility,g...Recently,polymer materials have been at the forefront of other materials in building high-performance flexible electronic skin(e-skin)devices due to con-spicuous advantages including excellent mechanical flexibility,good compatibil-ity,and high plasticity.However,most research works just paid considerable attention and effort to the design,construction,and possible application of e-skins that reproduce the tactile perception of the human skin sensory system.Compared with tactile sensing devices,e-skins that aim to imitate the non-contact sensing features in the sensory system of human skin tend to avoid undesired issues such as bacteria spreading and mechanical wear.To further promote the development of e-skins to the human skin sensory system where tactile perception and non-contact sensing complement each other,significant progress and advances have been achieved in the field of polymer materials enabled e-skins for both tactile perception and non-contact sensing applications.In this review,the latest progress in polymer material-based e-skins with regard to tactile,non-contact sensing capabilities and their practical applications are introduced.The fabrication strategies of polymer materials and their role in building high-performance e-skins for tactile and non-contact sensing are highlighted.Furthermore,we also review the research works that integrated the polymer-based tactile and non-contact e-skins into robots and prostheses,smart gloves,and VR/AR devices and addressed some representative problems to dem-onstrate their suitability in practical applications in human–machine interac-tions.Finally,the current challenges in the construction of high-performance tactile and non-contact e-skins are highlighted and promising properties in this direction,by taking advantage of the polymer materials,are outlined.展开更多
Skin-attachable electronics have garnered considerable research attention in health monitoring and artificial intelligence domains,whereas susceptibility to elec-tromagnetic interference(EMI),heat accumulation issues,...Skin-attachable electronics have garnered considerable research attention in health monitoring and artificial intelligence domains,whereas susceptibility to elec-tromagnetic interference(EMI),heat accumulation issues,and ultraviolet(UV)-induced aging problems pose significant constraints on their potential applications.Here,an ultra-elas-tic,highly breathable,and thermal-comfortable epidermal sensor with exceptional UV-EMI shielding performance and remarkable thermal conductivity is developed for high-fidelity monitoring of multiple human electrophysiological signals.Via filling the elastomeric microfibers with thermally conductive boron nitride nanoparticles and bridging the insulating fiber interfaces by plating Ag nanoparticles(NPs),an interwoven thermal con-ducting fiber network(0.72 W m^(-1) K^(-1))is constructed benefiting from the seamless thermal interfaces,facilitating unimpeded heat dissipation for comfort skin wearing.More excitingly,the elastomeric fiber substrates simultaneously achieve outstanding UV protection(UPF=143.1)and EMI shielding(SET>65,X-band)capabilities owing to the high electrical conductivity and surface plasmon resonance of Ag NPs.Furthermore,an electronic textile prepared by printing liquid metal on the UV-EMI shielding and thermally conductive nonwoven textile is finally utilized as an advanced epidermal sensor,which succeeds in monitoring different electrophysiological signals under vigorous electromagnetic interference.This research paves the way for developing protective and environmentally adaptive epidermal electronics for next-generation health regulation.展开更多
Neurologic function implemented soft organic electronic skin holds promise for wide range of applications,such as skin prosthetics,neurorobot,bioelectronics,human-robotic interaction(HRI),etc.Here,we report the develo...Neurologic function implemented soft organic electronic skin holds promise for wide range of applications,such as skin prosthetics,neurorobot,bioelectronics,human-robotic interaction(HRI),etc.Here,we report the development of a fully rubbery synaptic transistor which consists of all-organic materials,which shows unique synaptic characteristics existing in biological synapses.These synaptic characteristics retained even under mechanical stretch by 30%.We further developed a neurological electronic skin in a fully rubbery format based on two mechanoreceptors(for synaptic potentiation or depression)of pressure-sensitive rubber and an all-organic synaptic transistor.By converting tactile signals into Morse Code,potentiation and depression of excitatory postsynaptic current(EPSC)signals allow the neurological electronic skin on a human forearm to communicate with a robotic hand.The collective studies on the materials,devices,and their characteristics revealed the fundamental aspects and applicability of the all-organic synaptic transistor and the neurological electronic skin.展开更多
To date,hydrogels have gained increasing attentions as a flexible conductive material in fabricating soft electronics.However,it remains a big challenge to integrate multiple functions into one gel that can be used wi...To date,hydrogels have gained increasing attentions as a flexible conductive material in fabricating soft electronics.However,it remains a big challenge to integrate multiple functions into one gel that can be used widely under various conditions.Herein,a kind of multifunc-tional hydrogel with a combination of desirable characteristics,including remarkable transparency,high conductivity,ultra-stretchability,tough-ness,good fatigue resistance,and strong adhesive ability is presented,which was facilely fabricated through multiple noncovalent crosslinking strategy.The resultant versatile sensors are able to detect both weak and large deformations,which owns a low detection limit of 0.1%strain,high stretchability up to 1586%,ultrahigh sensitivity with a gauge factor up to 18.54,as well as wide pressure sensing range(0-600 kPa).Meanwhile,the fabrication of conductive hydrogel-based sensors is demonstrated for various soft electronic devices,including a flexible human-machine interactive system,the soft tactile switch,an integrated electronic skin for unprecedented nonplanar visualized pressure sensing,and the stretchable triboelectric nanogenerators with excellent biomechanical energy harvesting ability.This work opens up a simple route for multifunctional hydrogel and promises the practical application of soft and self-powered wearable electronics in various complex scenes.展开更多
Objective: The purpose of this study was to present the dosimetric study and evaluation the dose delivered to the skin tumor by using diode detector with total skin electron therapy (TSET). Methods: The total skin...Objective: The purpose of this study was to present the dosimetric study and evaluation the dose delivered to the skin tumor by using diode detector with total skin electron therapy (TSET). Methods: The total skin electron irradiation (TSEI) technique was used to treat ten patients with histological confirmed mycosis fungoides according to the Stanford staging system at the Radiotherapy Department, National Cancer Institute, Cairo University, Egypt. High dose rate electron beams with low electron energy 5 MeV from a Siemens linear accelerator were used for treatment. Diodes were calibrated at TSET distance 300 cm and field size (35 × 35) cm^2. Results: The result of diodes measurements showed the dose to flat surface of the body was within :1:10 % from the prescribed dose. Special areas of the body such as the perineum & eyelid showed large deviation up to 30% variation from the prescription dose. Conclusion: The diode results of this study will be used as a quality assurance check for all new patients treated with TSET and to compare it to the prescribed dose delivered to the patients. It is recommends to evaluate the diodes measurements for all patients throughout the full treatment cycle and to identify individually the boost dose areas.展开更多
Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide respons...Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide response range remains a challenge.Inspired by human skin,we select commercial silicon carbide sandpaper as a template to fabricate carbon nanotube(CNT)/polydimethylsiloxane(PDMS)composite film with a hierarchical structured surface(h-CNT/PDMS)through solution blending and blade coating and then assemble the h-CNT/PDMS composite film with interdigitated electrodes and polyurethane(PU)scotch tape to obtain an h-CNT/PDMS-based flexible pressure sensor.Based on in-situ optical images and finite element analysis,the significant compressive contact effect between the hierarchical structured surface of h-CNT/PDMS and the interdigitated electrode leads to enhanced pressure sensitivity and a wider response range(0.1661 kPa^(-1),0.4574 kPa^(-1)and 0.0989 kPa^(-1)in the pressure range of 0–18 kPa,18–133 kPa and 133–300 kPa)compared with planar CNT/PDMS composite film(0.0066 kPa^(-1)in the pressure range of 0–240 kPa).The prepared pressure sensor displays rapid response/recovery time,excellent stability,durability,and stable response to different loading modes(bending and torsion).In addition,our pressure sensor can be utilized to accurately monitor and discriminate various stimuli ranging from human motions to pressure magnitude and spatial distribution.This study supplies important guidance for the fabrication of flexible pressure sensors with superior sensing performance in next-generation wearable electronic devices.展开更多
Electronic skin and flexible wearable devices have attracted tremendous attention in the fields of human-machine interaction,energy storage,and intelligent robots.As a prevailing flexible pressure sensor with high per...Electronic skin and flexible wearable devices have attracted tremendous attention in the fields of human-machine interaction,energy storage,and intelligent robots.As a prevailing flexible pressure sensor with high performance,the piezoresistive sensor is believed to be one of the fundamental components of intelligent tactile skin.Furthermore,graphene can be used as a building block for highly flexible and wearable piezoresistive sensors owing to its light weight,high electrical conductivity,and excellent mechanical.This review provides a comprehensive summary of recent advances in graphene-based piezoresistive sensors,which we systematically classify as various configurations including one-dimensional fiber,two-dimensional thin film,and threedimensional foam geometries,followed by examples of practical applications for health monitoring,human motion sensing,multifunctional sensing,and system integration.We also present the sensing mechanisms and evaluation parameters of piezoresistive sensors.This review delivers broad insights on existing graphene-based piezoresistive sensors and challenges for the future generation of high-performance,multifunctional sensors in various applications.展开更多
Every year, millions of people incur damage to sensory receptors that interact with the external environment. Two areas of concern are hearing loss (affecting around 430 million) and burns (affecting 11 million annual...Every year, millions of people incur damage to sensory receptors that interact with the external environment. Two areas of concern are hearing loss (affecting around 430 million) and burns (affecting 11 million annually). Current treatments for burns involve skin grafts, which are expensive and prone to rejection by the body. Current treatments for hearing loss involve implants and hearing aids, which have limited sensitivity, need batteries and charging, are expensive, and are prone to infection. Thus, there is a need for a self-powered, flexible, biocompatible, antibacterial, and inexpensive solution that can respond to stimuli at a rate comparable to tissue. Piezoelectric materials convert mechanical energy into electricity, thus replicating touch and hearing by simulating nerve signals. In this study, piezoelectric membranes with varying ratios of polyvinylidene fluoride (PVDF) and zinc oxide (ZnO) were fabricated using electrospinning. These membranes were characterized with scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), stress-strain analysis, and piezoresponse testing. Results showed that increasing the amount of PVDF made the membrane more flexible but reduced its piezoelectric potential (decrease in PVDF β-phase). Increasing the amount of ZnO significantly increased piezoelectric potential (increase in PVDF β-phase) but degraded the flexibility and usability of the membrane. Therefore, a 1:1 w/w ratio of PVDF to ZnO is the optimum ratio for balancing both piezoelectric potential and flexibility. These results support the hypothesis that composites of PVDF and ZnO can help realize self-powered hearing rehab devices and wearable electronic skin.展开更多
Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PA...Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PAD)is the third most prevalent cardiovascular disease,but the means of diagnosing and monitoring this disease are limited because the affected area is usually in the non‐pulsatile area away from the heart.Herein,we report on an ultrathin and ultralight multi‐vital near‐infrared optoelectronic biosensor for the diagnosis and rehabilitation monitoring of regional tissue hemodynamics,which is suitable for mounting on the skin for long‐term measurement.The device can simultaneously detect tissue oxygen saturation,heart rate,arterial blood oxygen,and tissue perfusion and shows potential for various hypoxia monitoring applications.Moreover,the tissue hemodynamics detected by this device showed a highly accordance with the ankle‐brachial index and CT angiography obtained by traditional clinical methods.Therefore,our design was able to accurately diagnose and effectively evaluate PAD patients before and after surgery.The on‐skin optoelectronic biosensor shows potential in biological oxygen‐mediated behavior evaluation,injury‐state monitoring,PAD clinical diagnosis optimization,and after surgery care.展开更多
基金supported by the National Key R&D Program of China(Nos.2022 YFF 1202700 and 2022YFB3203500)National Natural Science Foundation of China(Nos.62225403,62375046,51973024,an d U19A2091)+2 种基金“111”Project(No.B13013)Natur al Sci ence Foundation of Jilin Pro vin ce(No.20230101113JC)the Funding from Jilin Pr ovince(No.20220502002GH).
文摘Recently,electronic skins and fl exible wearable devices have been developed for widespread applications in medical monitoring,artifi cial intelligence,human–machine interaction,and artifi cial prosthetics.Flexible proximity sensors can accurately perceive external objects without contact,introducing a new way to achieve an ultrasensitive perception of objects.This article reviews the progress of fl exible capacitive proximity sensors,fl exible triboelectric proximity sensors,and fl exible gate-enhanced proximity sensors,focusing on their applications in the electronic skin fi eld.Herein,their working mechanism,materials,preparation methods,and research progress are discussed in detail.Finally,we summarize the future challenges in developing fl exible proximity sensors.
基金support from the Contract Research(“Development of Breathable Fabrics with Nano-Electrospun Membrane,”CityU ref.:9231419)the National Natural Science Foundation of China(“Study of Multi-Responsive Shape Memory Polyurethane Nanocomposites Inspired by Natural Fibers,”Grant No.51673162)+1 种基金Startup Grant of CityU(“Laboratory of Wearable Materials for Healthcare,”Grant No.9380116)National Natural Science Foundation of China,Grant No.52073241.
文摘Electronic skins can monitor minute physiological signal variations in the human skins and represent the body’s state,showing an emerging trend for alternative medical diagnostics and human-machine interfaces.In this study,we designed a bioinspired directional moisture-wicking electronic skin(DMWES)based on the construction of heterogeneous fibrous membranes and the conductive MXene/CNTs electrospraying layer.Unidirectional moisture transfer was successfully realized by surface energy gradient and push-pull effect via the design of distinct hydrophobic-hydrophilic difference,which can spontaneously absorb sweat from the skin.The DMWES membrane showed excellent comprehensive pressure sensing performance,high sensitivity(maximum sensitivity of 548.09 kPa^(−1)),wide linear range,rapid response and recovery time.In addition,the single-electrode triboelectric nanogenerator based on the DMWES can deliver a high areal power density of 21.6μW m^(−2) and good cycling stability in high pressure energy harvesting.Moreover,the superior pressure sensing and triboelectric performance enabled the DMWES for all-range healthcare sensing,including accurate pulse monitoring,voice recognition,and gait recognition.This work will help to boost the development of the next-generation breathable electronic skins in the applications of AI,human-machine interaction,and soft robots.
基金This work was supported by the National Natural Science Foundation of China (No.61674078) and Dongrun- Yau Science Silver Award (Chemistry).
文摘Transparent, flexible electronic skin holds a wide range of applications in robotics, humanmachine interfaces, artificial intelligence, prosthetics, and health monitoring. Silver nanowire are mechanically flexible and robust, which exhibit great potential in transparent and electricconducting thin film. Herein, we report on a silver-nanowire spray-coating and electrodemicrostructure replicating strategy to construct a transparent, flexible, and sensitive electronic skin device. The electronic skin device shows highly sensitive piezo-capacitance response to pressure. It is found that micropatterning the surface of dielectric layer polyurethane elastomer by replicating from microstructures of natural-existing surfaces such as lotus leaf, silk, and frosted glass can greatly enhance the piezo-capacitance performance of the device. The microstructured pressure sensors based on silver nanowire exhibit good transparency, excellent flexibility, wide pressure detection range (0-150 kPa), and high sensitivity (1.28 kPa-1).
基金supported by National Key Basic Research Program of China(No.2017YFA0205301)Natural Science Foundation of China(31771081,81921002,and 8202010801)+2 种基金S&T Innovation 2025 Major Special Program of Ningbo(2018B10040)the Fundamental Research Funds for the Central Universities(22120210582)China Postdoctoral Science Foundation(2021TQ0247)。
文摘User-interactive electronic skin(e-skin) that could convert mechanical stimuli into distinguishable outputs displays tremendous potential for wearable devices and health care applications. However, the existing devices have the disadvantages such as complex integration procedure and lack of the intuitive signal display function. Here, we present a bioinspired user-interactive e-skin, which is simple in structure and can synchronously achieve digital electrical response and optical visualization upon external mechanical stimulus. The e-skin comprises a conductive layer with a carbon nanotubes/cellulose nanofibers/MXene nanohybrid network featuring remarkable electromechanical behaviors, and a stretchable elastomer layer, which is composed of silicone rubber and thermochromic pigments. Furthermore, the conductive nanohybrid network with outstanding Joule heating performance can generate controllable thermal energy under voltage input and then achieve the dynamic coloration of silicone-based elastomer. Especially, such an innovative fusion strategy of digital data and visual images enables the e-skin to monitor human activities with evermore intuition and accuracy. The simple design philosophy and reliable operation of the demonstrated e-skin are expected to provide an ideal platform for next-generation flexible electronics.
基金supported by the Hunan Provincial Technology Innovation Platform and Talent Program(2017XK2047)the Outstanding Youth Scientist Foundation of Hunan Province(2020JJ2001)+1 种基金Fundamental Research Funds for the Central Universities of P R China(531107050927)financial support from Hunan University for the Yuelu Young Scholars(JY-Q/008/2016).
文摘There is growing recognition that the developments in piezoresistive devices from personal healthcare to artificial intelli-gence,will emerge as de novo translational success in electronic skin.Here,we review the updates with regard to piezoresistive sensors including basic fundamentals,design and fabrication,and device performance.We also discuss the prosperous advances in piezoresistive sensor application,which offer perspectives for future electronic skin.
基金supported by the National Key R&D Program 2021YFC3002201 of Chinathe National Natural Science Foundation(U20A20168,61874065,51861145202)of ChinaThe authors are also thankful for the support of the Research Fund from the Beijing Innovation Center for Future Chip,the Independent Research Program of Tsinghua University(20193080047).
文摘With the aging of society and the increase in people’s concern for personal health,long-term physiological signal monitoring in daily life is in demand.In recent years,electronic skin(e-skin)for daily health monitoring applications has achieved rapid development due to its advantages in high-quality physiological signals monitoring and suitability for system integrations.Among them,the breathable e-skin has developed rapidly in recent years because it adapts to the long-term and high-comfort wear requirements of monitoring physiological signals in daily life.In this review,the recent achievements of breathable e-skins for daily physiological monitoring are systematically introduced and discussed.By dividing them into breathable e-skin electrodes,breathable e-skin sensors,and breathable e-skin systems,we sort out their design ideas,manufacturing processes,performances,and applications and show their advantages in long-term physiological signal monitoring in daily life.In addition,the development directions and challenges of the breathable e-skin are discussed and prospected.
基金supported by the National Natural Science Foundation of China(No.62074137)the Science and Technology Research and Development Program Joint Fund of Henan(No.232301420033)the China Postdoctoral Science Foundation(Nos.2021TQ0288 and 2022M712852).
文摘Neurological electronic skin(E-skin)can process and transmit information in a distributed manner that achieves effective stimuli perception,holding great promise in neuroprosthetics and soft robotics.Neurological E-skin with multifunctional perception abilities can enable robots to precisely interact with the complex surrounding environment.However,current neurological E-skins that possess tactile,thermal,and visual perception abilities are usually prepared with rigid materials,bringing difficulties in realizing biologically synapse-like softness.Here,we report a soft multifunctional neurological E-skin(SMNE)comprised of a poly(3-hexylthiophene)(P3HT)nanofiber polymer semiconductor-based stretchable synaptic transistor and multiple soft artificial sensory receptors,which is capable of effectively perceiving force,thermal,and light stimuli.The stretchable synaptic transistor can convert electrical signals into transient channel currents analogous to the biological excitatory postsynaptic currents.And it also possesses both short-term and long-term synaptic plasticity that mimics the human memory system.By integrating a stretchable triboelectric nanogenerator,a soft thermoelectric device,and an elastic photodetector as artificial receptors,we further developed an SMNE that enables the robot to make precise actions in response to various surrounding stimuli.Compared with traditional neurological E-skin,our SMNE can maintain the softness and adaptability of biological synapses while perceiving multiple stimuli including force,temperature,and light.This SMNE could promote the advancement of E-skins for intelligent robot applications.
基金supported by the National Natural Science Foundation of China(No.21978180).
文摘Language barrier is the main cause of disagreement.Sign language,which is a common language in all the worldwide language families,is difficult to be entirely popularized due to the high cost of learning as well as the technical barrier in real-time translation.To solve these problems,here,we constructed a wearable organohydrogel-based electronic skin(e-skin)with fast self-healing,strong adhesion,extraor-dinary anti-freezing and moisturizing properties for sign language recognition under complex environ-ments.The e-skin was obtained by using an acrylic network as the main body,aluminum(III)and bay-berry tannin as the crosslinking agent,water/ethylene glycol as the solvent system,and a polyvinyl al-cohol network to optimize the network performance.Using this e-skin,a smart glove was further built,which could carry out the large-scale data collection of common gestures and sign languages.With the help of the deep learning method,specific recognition and translation for various gestures and sign lan-guages could be achieved.The accuracy was 93.5%,showing the ultra-high classification accuracy of a sign language interpreter.In short,by integrating multiple characteristics and combining deep learning technology with hydrogel materials,the e-skin achieved an important breakthrough in human-computer interaction and artificial intelligence,and provided a feasible strategy for solving the dilemma of mutual exclusion between flexible electronic devices and human bodies.
基金This work was supported by the National Natural Science Foundation of China(No.62074137)the Key Research,Development,and Promotion Program of Henan Province(No.202102210004)China Postdoctoral Science Foundation(No.2021TQ0288).
文摘As a stretchable seamless device,electronic skin(E-skin)has drawn enormous interest due to its skin-like sensing capability.Besides the basic perception of force and temperature,multiple perception that is beyond existing functions of human skin is becoming an important direction for E-skin developments.However,the present E-skins for multiple perceptions mainly rely on different sensing materials and heterogeneous integration,resulting in a complex device structure.Additionally,their stretchability is usually achieved by the complicated microstructure design of rigid materials.Here,we report an intrinsically stretchable polymer semiconductor based E-skin with a simple structure for multiple perceptions of force,temperature,and visible light.The E-skin is on the basis of poly(3-hexylthiophene)(P3HT)nanofibers percolated polydimethylsiloxane(PDMS)composite polymer semiconductor,which is fabricated by a facile solution method.The E-skin shows reliable sensing capabilities when it is used to perceive strain,pressure,temperature,and visible light.Based on the E-skin,an intelligent robotic hand sensing and controlling system is further demonstrated.Compared with conventional E-skins for multiple perceptions,this E-skin only has a simple monolayer sensing membrane without the need of combining different sensing materials,heterogeneous integration,and complicated microstructure design.Such a strategy of utilizing intrinsically stretchable polymer semiconductor to create simple structured E-skin for multiple perceptions will promote the development of E-skins in a broad application scenario,such as artificial robotic skins,virtual reality,intelligent gloves,and biointegrated electronics.
基金supported by the National Natural Science Foundation of China(52073051,51925302,and 51873030)Fundamental Research Funds for the Central Universities(2232022 A-04)Shanghai Frontier Science Research Center for Modern Textiles,International Cooperation Fund of Science and Technology Commission of Shanghai Municipality(21130750100).
文摘Smart fibers are considered as promising materials for the fabrication of wearable electronic skins owing to their features such as superior flexibility,light weight,high specific area,and ease of modification.Besides,piezoelectric or triboelectric electronic skins can respond to mechanical stimulation and directly convert the mechanical energy into electrical power for self-use,thereby providing an attractive method for tactile sensing and motion perception.The incorporation of sensing capabilities into smart fibers could be a powerful approach to the development of self-powered electronic skins.Herein,we review several aspects of the recent advancements in the development of self-powered electronic skins constructed with smart fibers.The summarized aspects include functional material selection,structural design,pressure sensing mechanism,and proof-to-concept demonstration to practical application.In particular,various fabrication strategies and a wide range of practical applications have been systematically introduced.Finally,a critical assessment of the challenges and promising perspectives for the development of fiber-based electronic skins has been presented.
基金This work was supported partly by the China Postdoctoral Science Foundation(2023M730201)the Fundamental Research Funds for the Central Universities(2023XKRC027)+1 种基金the Fundamental Research Funds for the 173 project under Grant 2020-JCJQ-ZD-043the project under Grant 22TQ0403ZT07001 and Wei Zhen Limited Liability Company.
文摘Conformable and wire-less charging energy storage devices play important roles in enabling the fast development of wearable,non-contact soft electronics.However,current wire-less charging power sources are still restricted by limited flexural angles and fragile connection of components,resulting in the failure expression of performance and constraining their fur-ther applications in health monitoring wearables and moveable artificial limbs.Herein,we present an ultracompatible skin-like integrated wireless charging micro-supercapacitor,which building blocks(including electrolyte,electrode and substrate)are all evaporated by liquid precursor.Owing to the infiltration and permeation of the liquid,each part of the integrated device attached firmly with each other,forming a compact and all-in-one configuration.In addition,benefitting from the controllable volume of electrode solution precursor,the electrode thickness is easily regulated varying from 11.7 to 112.5μm.This prepared thin IWC-MSC skin can fit well with curving human body,and could be wireless charged to store electricity into high capacitive micro-supercapacitors(11.39 F cm-3)of the integrated device.We believe this work will shed light on the construction of skin-attachable electronics and irregular sensing microrobots.
基金National Research Foundation of Korea,Grant/Award Numbers:2018R1A6A1A03025242,2018R1D1A1A09083353。
文摘Recently,polymer materials have been at the forefront of other materials in building high-performance flexible electronic skin(e-skin)devices due to con-spicuous advantages including excellent mechanical flexibility,good compatibil-ity,and high plasticity.However,most research works just paid considerable attention and effort to the design,construction,and possible application of e-skins that reproduce the tactile perception of the human skin sensory system.Compared with tactile sensing devices,e-skins that aim to imitate the non-contact sensing features in the sensory system of human skin tend to avoid undesired issues such as bacteria spreading and mechanical wear.To further promote the development of e-skins to the human skin sensory system where tactile perception and non-contact sensing complement each other,significant progress and advances have been achieved in the field of polymer materials enabled e-skins for both tactile perception and non-contact sensing applications.In this review,the latest progress in polymer material-based e-skins with regard to tactile,non-contact sensing capabilities and their practical applications are introduced.The fabrication strategies of polymer materials and their role in building high-performance e-skins for tactile and non-contact sensing are highlighted.Furthermore,we also review the research works that integrated the polymer-based tactile and non-contact e-skins into robots and prostheses,smart gloves,and VR/AR devices and addressed some representative problems to dem-onstrate their suitability in practical applications in human–machine interac-tions.Finally,the current challenges in the construction of high-performance tactile and non-contact e-skins are highlighted and promising properties in this direction,by taking advantage of the polymer materials,are outlined.
基金financially supported by the National Natural Science Foundation of China(52373079,52161135302,52233006)the China Postdoctoral Science Foundation(2022M711355)the Natural Science Foundation of Jiangsu Province(BK20221540).
文摘Skin-attachable electronics have garnered considerable research attention in health monitoring and artificial intelligence domains,whereas susceptibility to elec-tromagnetic interference(EMI),heat accumulation issues,and ultraviolet(UV)-induced aging problems pose significant constraints on their potential applications.Here,an ultra-elas-tic,highly breathable,and thermal-comfortable epidermal sensor with exceptional UV-EMI shielding performance and remarkable thermal conductivity is developed for high-fidelity monitoring of multiple human electrophysiological signals.Via filling the elastomeric microfibers with thermally conductive boron nitride nanoparticles and bridging the insulating fiber interfaces by plating Ag nanoparticles(NPs),an interwoven thermal con-ducting fiber network(0.72 W m^(-1) K^(-1))is constructed benefiting from the seamless thermal interfaces,facilitating unimpeded heat dissipation for comfort skin wearing.More excitingly,the elastomeric fiber substrates simultaneously achieve outstanding UV protection(UPF=143.1)and EMI shielding(SET>65,X-band)capabilities owing to the high electrical conductivity and surface plasmon resonance of Ag NPs.Furthermore,an electronic textile prepared by printing liquid metal on the UV-EMI shielding and thermally conductive nonwoven textile is finally utilized as an advanced epidermal sensor,which succeeds in monitoring different electrophysiological signals under vigorous electromagnetic interference.This research paves the way for developing protective and environmentally adaptive epidermal electronics for next-generation health regulation.
基金support by the Office of Naval Research grant(N00014-18-1-2338)under Young Investigator Program,the National Science Foundation grants of CAREER(1554499),EFRI(1935291),and CPS(1931893).
文摘Neurologic function implemented soft organic electronic skin holds promise for wide range of applications,such as skin prosthetics,neurorobot,bioelectronics,human-robotic interaction(HRI),etc.Here,we report the development of a fully rubbery synaptic transistor which consists of all-organic materials,which shows unique synaptic characteristics existing in biological synapses.These synaptic characteristics retained even under mechanical stretch by 30%.We further developed a neurological electronic skin in a fully rubbery format based on two mechanoreceptors(for synaptic potentiation or depression)of pressure-sensitive rubber and an all-organic synaptic transistor.By converting tactile signals into Morse Code,potentiation and depression of excitatory postsynaptic current(EPSC)signals allow the neurological electronic skin on a human forearm to communicate with a robotic hand.The collective studies on the materials,devices,and their characteristics revealed the fundamental aspects and applicability of the all-organic synaptic transistor and the neurological electronic skin.
基金supported by the National Natural Science Foundation of China(51973166)the Key Research and Development Program of Hubei Province(2020BCA079).
文摘To date,hydrogels have gained increasing attentions as a flexible conductive material in fabricating soft electronics.However,it remains a big challenge to integrate multiple functions into one gel that can be used widely under various conditions.Herein,a kind of multifunc-tional hydrogel with a combination of desirable characteristics,including remarkable transparency,high conductivity,ultra-stretchability,tough-ness,good fatigue resistance,and strong adhesive ability is presented,which was facilely fabricated through multiple noncovalent crosslinking strategy.The resultant versatile sensors are able to detect both weak and large deformations,which owns a low detection limit of 0.1%strain,high stretchability up to 1586%,ultrahigh sensitivity with a gauge factor up to 18.54,as well as wide pressure sensing range(0-600 kPa).Meanwhile,the fabrication of conductive hydrogel-based sensors is demonstrated for various soft electronic devices,including a flexible human-machine interactive system,the soft tactile switch,an integrated electronic skin for unprecedented nonplanar visualized pressure sensing,and the stretchable triboelectric nanogenerators with excellent biomechanical energy harvesting ability.This work opens up a simple route for multifunctional hydrogel and promises the practical application of soft and self-powered wearable electronics in various complex scenes.
文摘Objective: The purpose of this study was to present the dosimetric study and evaluation the dose delivered to the skin tumor by using diode detector with total skin electron therapy (TSET). Methods: The total skin electron irradiation (TSEI) technique was used to treat ten patients with histological confirmed mycosis fungoides according to the Stanford staging system at the Radiotherapy Department, National Cancer Institute, Cairo University, Egypt. High dose rate electron beams with low electron energy 5 MeV from a Siemens linear accelerator were used for treatment. Diodes were calibrated at TSET distance 300 cm and field size (35 × 35) cm^2. Results: The result of diodes measurements showed the dose to flat surface of the body was within :1:10 % from the prescribed dose. Special areas of the body such as the perineum & eyelid showed large deviation up to 30% variation from the prescription dose. Conclusion: The diode results of this study will be used as a quality assurance check for all new patients treated with TSET and to compare it to the prescribed dose delivered to the patients. It is recommends to evaluate the diodes measurements for all patients throughout the full treatment cycle and to identify individually the boost dose areas.
基金supported by the National Natural Science Foundation of China(NO:51803191,12072325,52103100)the National Key R&D Program of China(2019YFA0706802)+1 种基金the 111 project(D18023)the Key Scientific and Technological Project of Henan Province(202102210038).
文摘Flexible pressure sensors have attracted wide attention due to their applications to electronic skin,health monitoring,and human-machine interaction.However,the tradeoff between their high sensitivity and wide response range remains a challenge.Inspired by human skin,we select commercial silicon carbide sandpaper as a template to fabricate carbon nanotube(CNT)/polydimethylsiloxane(PDMS)composite film with a hierarchical structured surface(h-CNT/PDMS)through solution blending and blade coating and then assemble the h-CNT/PDMS composite film with interdigitated electrodes and polyurethane(PU)scotch tape to obtain an h-CNT/PDMS-based flexible pressure sensor.Based on in-situ optical images and finite element analysis,the significant compressive contact effect between the hierarchical structured surface of h-CNT/PDMS and the interdigitated electrode leads to enhanced pressure sensitivity and a wider response range(0.1661 kPa^(-1),0.4574 kPa^(-1)and 0.0989 kPa^(-1)in the pressure range of 0–18 kPa,18–133 kPa and 133–300 kPa)compared with planar CNT/PDMS composite film(0.0066 kPa^(-1)in the pressure range of 0–240 kPa).The prepared pressure sensor displays rapid response/recovery time,excellent stability,durability,and stable response to different loading modes(bending and torsion).In addition,our pressure sensor can be utilized to accurately monitor and discriminate various stimuli ranging from human motions to pressure magnitude and spatial distribution.This study supplies important guidance for the fabrication of flexible pressure sensors with superior sensing performance in next-generation wearable electronic devices.
基金This work was supported by the NSFC(22075019,22035005)the Young Talent Program of Henan Agricultural University(30500601).
文摘Electronic skin and flexible wearable devices have attracted tremendous attention in the fields of human-machine interaction,energy storage,and intelligent robots.As a prevailing flexible pressure sensor with high performance,the piezoresistive sensor is believed to be one of the fundamental components of intelligent tactile skin.Furthermore,graphene can be used as a building block for highly flexible and wearable piezoresistive sensors owing to its light weight,high electrical conductivity,and excellent mechanical.This review provides a comprehensive summary of recent advances in graphene-based piezoresistive sensors,which we systematically classify as various configurations including one-dimensional fiber,two-dimensional thin film,and threedimensional foam geometries,followed by examples of practical applications for health monitoring,human motion sensing,multifunctional sensing,and system integration.We also present the sensing mechanisms and evaluation parameters of piezoresistive sensors.This review delivers broad insights on existing graphene-based piezoresistive sensors and challenges for the future generation of high-performance,multifunctional sensors in various applications.
文摘Every year, millions of people incur damage to sensory receptors that interact with the external environment. Two areas of concern are hearing loss (affecting around 430 million) and burns (affecting 11 million annually). Current treatments for burns involve skin grafts, which are expensive and prone to rejection by the body. Current treatments for hearing loss involve implants and hearing aids, which have limited sensitivity, need batteries and charging, are expensive, and are prone to infection. Thus, there is a need for a self-powered, flexible, biocompatible, antibacterial, and inexpensive solution that can respond to stimuli at a rate comparable to tissue. Piezoelectric materials convert mechanical energy into electricity, thus replicating touch and hearing by simulating nerve signals. In this study, piezoelectric membranes with varying ratios of polyvinylidene fluoride (PVDF) and zinc oxide (ZnO) were fabricated using electrospinning. These membranes were characterized with scanning electron microscopy (SEM), X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), stress-strain analysis, and piezoresponse testing. Results showed that increasing the amount of PVDF made the membrane more flexible but reduced its piezoelectric potential (decrease in PVDF β-phase). Increasing the amount of ZnO significantly increased piezoelectric potential (increase in PVDF β-phase) but degraded the flexibility and usability of the membrane. Therefore, a 1:1 w/w ratio of PVDF to ZnO is the optimum ratio for balancing both piezoelectric potential and flexibility. These results support the hypothesis that composites of PVDF and ZnO can help realize self-powered hearing rehab devices and wearable electronic skin.
基金The National Key Research and Development program,Grant/Award Number:2021YFA1401103China National Funds for Distinguished Young Scientists,Grant/Award Number:61825403The National Natural Science Foundation of China,Grant/Award Numbers:61921005,61674078。
文摘Evaluation of the oxygen‐mediated effects of clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously.For example,peripheral arterial disease(PAD)is the third most prevalent cardiovascular disease,but the means of diagnosing and monitoring this disease are limited because the affected area is usually in the non‐pulsatile area away from the heart.Herein,we report on an ultrathin and ultralight multi‐vital near‐infrared optoelectronic biosensor for the diagnosis and rehabilitation monitoring of regional tissue hemodynamics,which is suitable for mounting on the skin for long‐term measurement.The device can simultaneously detect tissue oxygen saturation,heart rate,arterial blood oxygen,and tissue perfusion and shows potential for various hypoxia monitoring applications.Moreover,the tissue hemodynamics detected by this device showed a highly accordance with the ankle‐brachial index and CT angiography obtained by traditional clinical methods.Therefore,our design was able to accurately diagnose and effectively evaluate PAD patients before and after surgery.The on‐skin optoelectronic biosensor shows potential in biological oxygen‐mediated behavior evaluation,injury‐state monitoring,PAD clinical diagnosis optimization,and after surgery care.