It is widely assumed that fetal ischemic brain injury during labor derives almost exclusively from severe, systemic hypoxemia with marked neonatal depression and acidemia. Severe asphyxia, however, is one of several c...It is widely assumed that fetal ischemic brain injury during labor derives almost exclusively from severe, systemic hypoxemia with marked neonatal depression and acidemia. Severe asphyxia, however, is one of several causes of perinatal neurological injury and may not be the most common;most neonates diagnosed with hypoxic-ischemic encephalopathy do not have evidence of severe asphyxia. Sepsis, direct brain trauma, and drug or toxin exposure account for some cases, while mechanical forces of labor and delivery that increase fetal intracranial pressure sufficiently to impair brain perfusion may also contribute. Because of bony compliance and mobile suture lines, the fetal skull changes shape and redistributes cerebrospinal fluid during labor according to constraints imposed by contractions, and bony and soft tissue elements of the birth canal as the head descends. These accommodations, including the increase in intracranial pressure, are adaptive and necessary for efficient descent of the head while safeguarding cerebral blood flow. Autonomic reflexes mediated through central receptors normally provide ample protection of the brain from the considerable pressure exerted on the skull. On occasion, those forces, which are transmitted intracranially, may overcome the various adaptive anatomical, cardiovascular, metabolic, and neurological mechanisms that maintain cerebral perfusion and oxygen availability, resulting in ischemic brain injury. Accepting the notion of a potentially adverse impact of fetal head compression suggests that avoidance of excessive uterine activity and of relentless pushing without steady progress in descent may offer protection for the fetal brain during parturition. Excessive head compression should be considered in the differential diagnosis of ischemic encephalopathy.展开更多
目的探讨Kiwi胎头真空吸引器在阴道助产分娩中的应用价值。方法选取2020年7月至2023年3月于扬州大学临床医学院使用Kiwi胎头真空吸引器实施胎头吸引的初产孕妇30例为胎吸组,同时选取计划阴道分娩而后因特殊原因行剖宫产终止妊娠的孕妇2...目的探讨Kiwi胎头真空吸引器在阴道助产分娩中的应用价值。方法选取2020年7月至2023年3月于扬州大学临床医学院使用Kiwi胎头真空吸引器实施胎头吸引的初产孕妇30例为胎吸组,同时选取计划阴道分娩而后因特殊原因行剖宫产终止妊娠的孕妇23例为剖宫产组。比较2组术中及术后情况及新生儿相关指标。结果2组第二产程时间、产时出血量、产后24 h出血量、产后住院时间及软产道损伤、产后会阴水肿发生情况比较,差异无统计学意义(P>0.05)。2组产后尿潴留发生率比较,差异有统计学意义(P<0.05)。2组新生儿出生体重及头皮血肿、颅内出血发生情况比较,差异无统计学意义(P>0.05)。胎吸组新生儿中,3例娩出后1 min Apgar评分分别为8、9、6分。剖宫产组新生儿中,仅1例娩出后1 min Apgar评分为7分。胎吸组新生儿中,有9例(30.00%)因黄疸、呼吸急促、窒息等原因转至新生儿科;剖宫产组新生儿中,有4例(17.39%)因黄疸、新生儿低血糖、鼻塞等原因转至新生儿科。胎吸组转科新生儿中,2例(15.38%)出现高总胆红素血症,剖宫产组未出现高总胆红素血症。胎吸组、剖宫产组新生儿动脉血pH值分别为(7.38±0.02)、(7.45±0.02),二者比较差异有统计学意义(P<0.05)。结论Kiwi胎头真空吸引器操作简便,适用范围广,其应用于阴道助产中有效缩短产程,降低剖宫产率、产妇及新生儿相关并发症发生率。展开更多
文摘It is widely assumed that fetal ischemic brain injury during labor derives almost exclusively from severe, systemic hypoxemia with marked neonatal depression and acidemia. Severe asphyxia, however, is one of several causes of perinatal neurological injury and may not be the most common;most neonates diagnosed with hypoxic-ischemic encephalopathy do not have evidence of severe asphyxia. Sepsis, direct brain trauma, and drug or toxin exposure account for some cases, while mechanical forces of labor and delivery that increase fetal intracranial pressure sufficiently to impair brain perfusion may also contribute. Because of bony compliance and mobile suture lines, the fetal skull changes shape and redistributes cerebrospinal fluid during labor according to constraints imposed by contractions, and bony and soft tissue elements of the birth canal as the head descends. These accommodations, including the increase in intracranial pressure, are adaptive and necessary for efficient descent of the head while safeguarding cerebral blood flow. Autonomic reflexes mediated through central receptors normally provide ample protection of the brain from the considerable pressure exerted on the skull. On occasion, those forces, which are transmitted intracranially, may overcome the various adaptive anatomical, cardiovascular, metabolic, and neurological mechanisms that maintain cerebral perfusion and oxygen availability, resulting in ischemic brain injury. Accepting the notion of a potentially adverse impact of fetal head compression suggests that avoidance of excessive uterine activity and of relentless pushing without steady progress in descent may offer protection for the fetal brain during parturition. Excessive head compression should be considered in the differential diagnosis of ischemic encephalopathy.
文摘目的探讨Kiwi胎头真空吸引器在阴道助产分娩中的应用价值。方法选取2020年7月至2023年3月于扬州大学临床医学院使用Kiwi胎头真空吸引器实施胎头吸引的初产孕妇30例为胎吸组,同时选取计划阴道分娩而后因特殊原因行剖宫产终止妊娠的孕妇23例为剖宫产组。比较2组术中及术后情况及新生儿相关指标。结果2组第二产程时间、产时出血量、产后24 h出血量、产后住院时间及软产道损伤、产后会阴水肿发生情况比较,差异无统计学意义(P>0.05)。2组产后尿潴留发生率比较,差异有统计学意义(P<0.05)。2组新生儿出生体重及头皮血肿、颅内出血发生情况比较,差异无统计学意义(P>0.05)。胎吸组新生儿中,3例娩出后1 min Apgar评分分别为8、9、6分。剖宫产组新生儿中,仅1例娩出后1 min Apgar评分为7分。胎吸组新生儿中,有9例(30.00%)因黄疸、呼吸急促、窒息等原因转至新生儿科;剖宫产组新生儿中,有4例(17.39%)因黄疸、新生儿低血糖、鼻塞等原因转至新生儿科。胎吸组转科新生儿中,2例(15.38%)出现高总胆红素血症,剖宫产组未出现高总胆红素血症。胎吸组、剖宫产组新生儿动脉血pH值分别为(7.38±0.02)、(7.45±0.02),二者比较差异有统计学意义(P<0.05)。结论Kiwi胎头真空吸引器操作简便,适用范围广,其应用于阴道助产中有效缩短产程,降低剖宫产率、产妇及新生儿相关并发症发生率。
