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Determination of Total Flavonoids in Acanthopanax senticosus(Rupr. et Maxim.) Harms by Enzymolysis and Its Technological Optimization
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作者 Li Xinzhi Wang Yudan +4 位作者 Wang Meiliang Liu Tianyang Gao Ruihua Qiu Youwen Zhang Shunjie 《Journal of Northeast Agricultural University(English Edition)》 CAS 2024年第1期53-60,共8页
In order to optimize the ultrasonic extraction technique for the total flavonoid of leaf yellows plus, the contents of 21 leaf yellows plus total flavonoid from four regions in Heilongjiang Province were comparatively... In order to optimize the ultrasonic extraction technique for the total flavonoid of leaf yellows plus, the contents of 21 leaf yellows plus total flavonoid from four regions in Heilongjiang Province were comparatively analyzed. The ultrasonic extraction technology was optimized by Box-Behnken response surface method, and the total flavonoid content of 21 kinds of Acanthopanax senticosus(Rupr. et Maxim.) Harms from different producing areas were analyzed by cluster analysis. The optimal process conditions were determined as ultrasonic time 30 min, solid-liquid ratio 1 : 12 and ultrasonic power 250 W, and the average yield of the total flavonoid was 1.453 mg·g^ (-1). By optimizing the ultrasonic-assisted extraction method, the total flavonoid content from different producing areas was compared in the experiment, which provided certain data support for the optimization of the extraction process in the future and laid a certain theoretical foundation for the quality analysis of Chinese medicinal materials. 展开更多
关键词 Acanthopanax senticosus(Rupr.et Maxim.)harms total flavonoid Box-Behnken response surface test ultrasonic-assisted extraction
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Benefits and harms of screening for hepatocellular carcinoma in high-risk populations: systematic review and meta-analysis
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作者 Jichun Yang Zhirong Yang +4 位作者 Xueyang Zeng Shuqing Yu Le Gao Yu Jiang Feng Sun 《Journal of the National Cancer Center》 2023年第3期175-185,共11页
Objective:The incidence and mortality of hepatocellular carcinoma(HCC)have been increasing around the world.Current guidelines recommend HCC screening in high-risk population.However,the strength of evidence of ben-ef... Objective:The incidence and mortality of hepatocellular carcinoma(HCC)have been increasing around the world.Current guidelines recommend HCC screening in high-risk population.However,the strength of evidence of ben-efits and harms of HCC screening to support the recommendation was unclear.The objective is to systematically synthesize current evidence on the benefits and harms of HCC screening.Methods:We searched PubMed and nine other databases until August 20,2021.We included cohort studies and RCTs that compared the benefits and harms of screening and non-screening in high-risk population of HCC.Case series studies that reported harms of HCC screening were also included.Pooled risk ratio(RR),according to HCC screening status,was calculated for each benefit outcome(e.g.,HCC mortality,survival rate,proportion of early HCC),using head-to-head meta-analysis.The harmful outcomes(e.g.,proportion of physiological harms provided by non-comparative studies were pooled by prevalence of meta-analysis).Analysis on publication bias and quality of life,subgroup analysis,and sensitivity analysis were also conducted.Results:We included 70 studies,including four random clinical trials(RCTs),63 cohort studies,three case se-ries studies.The meta-analysis of RCTs showed HCC screening was significantly associated with reduced HCC mortality(RR[risk ratio],0.73[95%CI,0.56-0.96];I^(2)=75.1%),prolonged overall survival rates(1-year,RR,1.72[95%CI,1.13-2.61];I^(2)=72.5%;3-year,RR,2.86[95%CI,1.78-4.58];I^(2)=10.1%;and 5-year,RR,2.76[95%CI,1.37-5.54];I^(2)=28.3%),increased proportion of early HCC detection(RR,2.68[95%CI,1.77-4.06];I^(2)=50.4%).Similarly,meta-analysis of cohort studies indicated HCC screening was more effective than non-screening.However,pooled proportion of physiological harms was 16.30%(95%CI:8.92%-23.67%)and most harms were of a mild to moderate severity.Conclusion:The existing evidence suggests HCC screening is more effective than non-screening in high-risk pop-ulation.However,harms of screening should not be ignored. 展开更多
关键词 Hepatocellular carcinoma SCREENING BENEFITS harms META-ANALYSIS
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Benefits and harms of endoscopic screening for gastric cancer 被引量:10
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作者 Chisato Hamashima 《World Journal of Gastroenterology》 SCIE CAS 2016年第28期6385-6392,共8页
Gastric cancer has remained a serious burden worldwide, particularly in East Asian countries. However, nationwide prevention and screening programs for gastric cancer have not yet been established in most countries ex... Gastric cancer has remained a serious burden worldwide, particularly in East Asian countries. However, nationwide prevention and screening programs for gastric cancer have not yet been established in most countries except in South Korea and Japan. Although evidence regarding the effectiveness of endoscopic screening for gastric cancer has been increasingly accumulated, such evidence remains weak because it is based on results from studies other than randomized controlled trials. Specifically, evidence was mostly based on the results of cohort and case-control studies mainly conducted in South Korea and Japan. However, the consistent positive results from these studies suggest promising evidence of mortality reduction from gastric cancer by endoscopic screening. The major harms of endoscopic screening include infection, adverse effects, false-positive results, and overdiagnosis. Despite the possible harms of endoscopic screening, information regarding these harms remains insufficient. To provide appropriate cancer screening, a balance of benefits and harms should always be considered when cancer screening is introduced as a public policy. Quality assurance is very important for the implementation of cancer screening to provide high-quality and safe screening and minimize harms. Endoscopic screening for gastric cancer has shown promising results, and thus deserves further evaluation to reliably establish its effectiveness and optimal use. 展开更多
关键词 Gastric cancer Cancer screening Upper gastrointestinal endoscopy Mortality reduction Cohort study Case-control study harms
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Supercritical Fluid Extraction of Total Flavonoids from Leaves of Acanthopanax Senticosus Harms 被引量:13
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作者 LIU Chun-ming ZHAO Ji-min +1 位作者 LI Hong-mei SONG Feng-rui 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2007年第2期233-236,共4页
The herbal plant Acanthopanax Senticosus Harms is natural herb of Changbaishan in Jilin Province of China, which belongs to the Araliaceae family. As the ingredients of folk medicine, it has long been used to treat a ... The herbal plant Acanthopanax Senticosus Harms is natural herb of Changbaishan in Jilin Province of China, which belongs to the Araliaceae family. As the ingredients of folk medicine, it has long been used to treat a variety of human diseases, such as cerebrovascular disease, diabetes, tumor, isochemic heart diseases, hypertension, rheumatic arthritis, etc. E2,33. Flavonoids, a class of constituent compounds, which have a broad distribution in the nature and are found in Acanthopanax Senticosus Harms, have gained particular attention. A number of studies have shown that flavonoid compounds have wide biological activities, such as anti-aging, anticancer, anti-HIV, 展开更多
关键词 Supercritical fluid extraction(SFE) Acarahopanax Senticosus harms FLAVONOIDS
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Three new compounds from the leaves of Acanthopanax senticosus Harms 被引量:7
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作者 Zhi 《Chinese Chemical Letters》 SCIE CAS CSCD 2010年第6期702-705,共4页
Three new compounds named (2E)prenyl benzoate-4-O-α-L-arabinopyranosyl (1→6) β-D-glucopyranoside (1), 7-methoxy-8-O-β-D-glucopyranosyl coumarin (2), and 3,4'-dihydroxy-3'-methoxy benzenepentanoic acid (3) ... Three new compounds named (2E)prenyl benzoate-4-O-α-L-arabinopyranosyl (1→6) β-D-glucopyranoside (1), 7-methoxy-8-O-β-D-glucopyranosyl coumarin (2), and 3,4'-dihydroxy-3'-methoxy benzenepentanoic acid (3) were isolated from the leaves of Acanthopanax senticosus Harms. The structures of new compounds were determined by means of 2D NMR experiments and chemical methods. 展开更多
关键词 Acanthopanax senticosus harms Prenyl benzoate Coumarin Benzenepentanoic acid
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Microwave Assisted-extraction of Flavonols from Acanthopanax Senticosus Harms and High-performance Liquid Chromatography Analysis
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作者 LIU Yan-bo 《Chemical Research in Chinese Universities》 SCIE CAS CSCD 2009年第4期439-442,共4页
Flavonols were extracted from Acanthopanax Senticosus Harms by Soxhlet extraction(SE),atmospheric pressure microwave-assisted extraction(AMAE) and pressurized microwave-assisted extraction(PMAE).The influences o... Flavonols were extracted from Acanthopanax Senticosus Harms by Soxhlet extraction(SE),atmospheric pressure microwave-assisted extraction(AMAE) and pressurized microwave-assisted extraction(PMAE).The influences of experimental conditions,such as concentration of ethanol in the eluent,microwave irradiation time,etc.on the extraction yield were studied.Four flavonols(hyperin,rutin,quercitrin and quercetin) in the extracts were determined quantitatively by HPLC method.The experimental results demonstrate the advantages of PMAE and AMAE over those of conventional SE,that is the extraction time is dramatically reduced,and the yields of flavonols are effective improved.Although the yield of flavonols is higher and the extraction time is shorter by PMAE than those of AMAE,flavonols are easy to be decomposed over a certain time. 展开更多
关键词 Acanthopanax Senticosus harms FLAVONOLS EXTRACTION
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Cooperation Benefits Both Sides While Confrontation Harms——Thoughts on Strategic Positioning of Sino-U.S. Relations
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作者 Ma Zhengang 《China International Studies》 2006年第1期35-54,共20页
关键词 rate Relations Thoughts on Strategic Positioning of Sino-U.S Cooperation Benefits Both Sides While Confrontation harms
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A Novel Method to Fix Type C3 Distal Femur Fractures with Bone Defect Loss Using “Harms Cage”
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作者 Shyam R. Mukhi Poonam Mukhi +1 位作者 Luv Mukhi Kush Mukhi 《Yangtze Medicine》 2017年第2期96-103,共8页
A case of compound C3 distal femur fracture with 12 cm bone defect. After thorough debridement, the Harms cage was used to reconstruct the medial column and the fracture was fixed with the locking distal femur plate l... A case of compound C3 distal femur fracture with 12 cm bone defect. After thorough debridement, the Harms cage was used to reconstruct the medial column and the fracture was fixed with the locking distal femur plate laterally. The Harms cage prevents the cantilever effect and eliminates the need for medial plating. This avoids another medial incision and preserves medial biology. At 18 months’ follow-up, plain radiographs demonstrated full reconstruction of the medial column with good range of motion at the knee joint. This technique avoids the need of dual plating in these fractures with good results. 展开更多
关键词 DISTAL Void DISTAL FEMUR Fracture harms CAGE
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Optimization of Extraction Technology and Determination of Content of Total Phenols of Leaves in Acanthopanax giraldii Harms
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作者 Wei ZHAO Yijun CHEN +1 位作者 Chunlin LIU Yuan LIU 《Medicinal Plant》 2017年第1期35-37,42,共4页
[Objectives] To determine the optimum extraction technology for total phenols of leaves in Acanthopanax giraldii Harms.[Methods]The single factor test and orthogonal design were adopted to study the extraction technol... [Objectives] To determine the optimum extraction technology for total phenols of leaves in Acanthopanax giraldii Harms.[Methods]The single factor test and orthogonal design were adopted to study the extraction technology for total phenols of leaves in Acanthopanax giraldii Harms. [Results]The optimum extraction conditions were determined as follows: extraction solvent( 70% methanol),solid-liquid ratio( 1∶ 35),and reflux extraction time( 60 min). Under these conditions,the yield of crude extract from total phenols of leaves in Acanthopanax giraldii Harms was 38. 67 mg/g.[Conclusions] The technology was simple,and of low cost and high extraction rate,suitable for the extraction of total phenols of leaves in Acanthopanax giraldii Harms. 展开更多
关键词 ACANTHOPANAX giraldii harms LEAVES Content TOTAL PHENOLS Optimization process ORTHOGONAL design
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Harms of Mycotoxins to Animals and Research Progress of Detection Methods
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作者 Guo Shijin Zhang Zhimei +3 位作者 Tang Shiyun Fu Shijun Li Ling Shen Zhiqiang 《Animal Husbandry and Feed Science》 CAS 2022年第4期21-24,共4页
Mycotoxin is widely distributed in various feedstuffs and feeds of animals.Mycotoxin not only causes feed deterioration,but also leads to various diseases of animals,or even results in acute toxic death,causing great ... Mycotoxin is widely distributed in various feedstuffs and feeds of animals.Mycotoxin not only causes feed deterioration,but also leads to various diseases of animals,or even results in acute toxic death,causing great harm to the breeding industry.In this paper,the harm of mycotoxin to animals and its detection methods in feed and animals are summarized and analyzed,so as to provide the reference basis for further improving the detection methods of mycotoxin and reducing the harm of mycotoxin to breeding industry. 展开更多
关键词 MYCOTOXIN HARM Detection method
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CONSORT Harms 2022对中药复方报告的启示
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作者 郑蕊 王爽秋 +3 位作者 陈卓 万思琦 邱瑞瑾 商洪才 《中国循证医学杂志》 CSCD 北大核心 2024年第5期617-620,共4页
高质量的随机对照试验可平衡组间混杂因素,是提供获益与危害综合信息的重要来源。为进一步提高随机对照试验中干预措施危害相关信息的报告质量,试验报告统一标准(consolidated standards of reporting trials,CONSORT)工作组更新发布了C... 高质量的随机对照试验可平衡组间混杂因素,是提供获益与危害综合信息的重要来源。为进一步提高随机对照试验中干预措施危害相关信息的报告质量,试验报告统一标准(consolidated standards of reporting trials,CONSORT)工作组更新发布了CONSORT Harms 2022声明。中药复方在运用中,有配伍禁忌、有毒中药等独特之处。CONSORT Harms 2022提示中药复方危害需要规范报告,研究者应注意提升研究团队专业素养、开发适宜中药复方临床随机对照试验危害报告规范、相关规范纳入杂志发表要求等,为中医药走向世界的普及与推广提供必要基础。 展开更多
关键词 随机对照试验 CONSORT harms 安全性 中医药 方法学
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根据CONSORT HARMs声明评价雷公藤制剂相关肾毒性RCT的报告质量 被引量:11
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作者 冯雪 方赛男 +2 位作者 高雨鑫 刘建平 陈薇 《中国中药杂志》 CAS CSCD 北大核心 2018年第3期440-445,共6页
根据CONSORT HARMs声明评价以雷公藤中成药为干预或对照措施的RCT关于肾毒性的报告情况。根据CONSORT HARMs声明对纳入的雷公藤制剂相关肾毒性RCT研究进行报告质量评价,计算每个研究符合CONSORT HARMs声明的条目,评价雷公藤制剂相关RCT... 根据CONSORT HARMs声明评价以雷公藤中成药为干预或对照措施的RCT关于肾毒性的报告情况。根据CONSORT HARMs声明对纳入的雷公藤制剂相关肾毒性RCT研究进行报告质量评价,计算每个研究符合CONSORT HARMs声明的条目,评价雷公藤制剂相关RCT中其肾毒性相关不良反应的报告质量,总结国内研究肾毒性相关不良反应报告的问题。共纳入16项RCT,平均每个研究符合7个条目,雷公藤制剂相关肾毒性RCT研究的报告质量较差,报告的最不重复的条目为:使用已验证过的工具报告不良反应、提及不良反应的编码采用的标准、在方法中描述如何及何时收集不良反应的数据、描述不良反应是如何归因于雷公藤的、明确的提出是谁报告的不良反应、描述不良反应的分析方法、描述收集复发不良反应数据的方法、描述与危害相关的任何亚组分析和探索性分析。建议将来中药不良反应的相关研究,严格按照CONSORT HARMs建议的条目对研究进行详细报告。此外,也应考虑到中药自身的特点,详细的报告中药的组成、剂量、服用时间、联合用药及研究对象的辨证分型。 展开更多
关键词 CONSORT harms声明 雷公藤制剂 肾毒性 报告质量 随机对照试验
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PRISMA harms清单简介及其对安全性系统评价报告规范的重要性 被引量:2
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作者 廖星 陈薇 +1 位作者 刘雅莉 谢雁鸣 《中国中西医结合杂志》 CAS CSCD 北大核心 2019年第3期350-357,共8页
目前普通系统评价/Meta分析都被要求遵循PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)进行规范报告。PRISMA harms清单是PRISMA报告规范的衍生版,其主要针对安全性系统评价如何进行报告提出条件要求。P... 目前普通系统评价/Meta分析都被要求遵循PRISMA(Preferred Reporting Items for Systematic Reviews and Meta-Analyses)进行规范报告。PRISMA harms清单是PRISMA报告规范的衍生版,其主要针对安全性系统评价如何进行报告提出条件要求。PRISMA harms清单包括标题、摘要、前言、方法、结果、讨论和资助等需要报告的27个条目内容。该规范包括了清单、详尽的解释性文本以方便使用。通过应用PRISMA harms清单,作者、期刊编辑和同行评议者可促进安全性系统评价报告的质量。 展开更多
关键词 PRISMA harms清单 安全性系统评价 报告规范
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The abundance,distribution,and enrichment mechanism of harmful trace elements in coals from Guizhou,Southwestern China
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作者 Hui Hou Wei Cheng +1 位作者 Ruidong Yang Yan Zhang 《Acta Geochimica》 EI CAS CSCD 2024年第5期889-903,共15页
Coal seams can enrich a variety of harmful trace elements under specific geological conditions.The spatial distribution of harmful trace elements in coal is extremely uneven,and the distribution characteristics of eac... Coal seams can enrich a variety of harmful trace elements under specific geological conditions.The spatial distribution of harmful trace elements in coal is extremely uneven,and the distribution characteristics of each element content are different.The harmful elements released in the process of coal mining and utilization will cause serious harm to the environment and the human body.It is of great resource significance to study the geochemistry of coal that affects the enrichment and distribution characteristics of harmful trace elements.Based on the domestic and foreign literature on coal geochemistry in Guizhou published by previous investigators,this study counted 1097 sample data from 23 major coal-producing counties in Guizhou Province,systematically summarized the relevant research results of harmful trace elements in the coal of Guizhou,and revealed the overall distribution and enrichment characteristics of harmful trace elements in the coal of Guizhou.The results show that the average contents of Cd,Pb,Se,Cu,Mo,U,V,As,Hg,and Cr in coal of Guizhou are higher than those in Chinese coal and world coal.A variety of harmful trace elements in the coal of Guizhou have high background values,especially in Liupanshui,Xingyi and Qianbei coalfield.The enrichment of various harmful trace elements in the Late Permian coal in Guizhou is mainly related to the combined action of various geological and geochemical factors.The supply of terrigenous debris and sedimentary environment may be the basic background of the enrichment of harmful elements in western Guizhou,while low-temperature hydrothermal activity and volcanic ash deposition may be the main reasons for the enrichment of harmful elements in southwestern Guizhou. 展开更多
关键词 Harmful trace elements Distribution characteristics Enrichment law Geological and geochemical features GUIZHOU
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Harm of Hail to Crops and Countermeasures of Artificial Hail Suppression in Ulanqab City
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作者 Pei WANG Tengge'er WU Jinhua LIU 《Meteorological and Environmental Research》 2024年第2期62-63,70,共3页
Hail is one of meteorological disasters affecting crop growth in Ulanqab City.It happens frequently from May to September,and this period is also the main growing season of crops.In this period,hail will cause damage ... Hail is one of meteorological disasters affecting crop growth in Ulanqab City.It happens frequently from May to September,and this period is also the main growing season of crops.In this period,hail will cause damage to crops,make farmland soil harden,and bring varying degrees of harm to agricultural production.Artificial hail suppression is an important scientific and technological means for disaster prevention and mitigation.It is necessary to strengthen the monitoring,analysis and forecast of severe convection weather,intensify the release of early warning information of hail weather,provide accurate and reliable real-time information for the implementation of artificial hail suppression operations,strengthen the implementation of artificial weather modification,effectively carry out artificial hail suppression operations,and avoid and reduce the impact of hail disaster. 展开更多
关键词 HAIL CROPS HARM Artificial hail suppression Ulanqab City
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The Evaluation of Social Sharing Nets Users’ Fundamental Principals According to Nickname Usage and Time Spent
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作者 Mehmet Ali Seven Mustafa Çağrı Engin +1 位作者 Mehmet Yıldız Ali Osman Engin 《Advances in Internet of Things》 2023年第2期31-62,共32页
This work;It was made to determine the positive and negative usage information, attitudes and behaviors of social networking networks for users. Today, it is well known how the wide social effects of social networking... This work;It was made to determine the positive and negative usage information, attitudes and behaviors of social networking networks for users. Today, it is well known how the wide social effects of social networking sites are widespread and effective. As far as it can be followed from written and visual media, it causes significant damages for attitudes and behaviors for individuals. Looking at the results of the study, it seems impossible to limit the time and necessity of these networks for people, but it is understood that people force their limits and capacity. It was determined that the general acceptance and rejection areas are mixed and the dominant distinctive effects were weakened. Unable to prevent social dissolution and deterioration was realized by these social networks of networks. However, we cannot only talk about negative effects because their positive effects should be mentioned. Data were obtained in this direction. For example, some segments encourage the users of these sites to have more freedom, to develop democracy and human rights awareness. However, the real problem is when and where to stand. This study;Social networking networks use information, attitudes and behaviors;It was carried out for the purpose of evaluating the use of nicknames and networks for the use of networks. The data of the study were obtained by the application of a questionnaire and the data obtained were analyzed with appropriate statistical analysis methods. In the first part of the study, field study/operational concept scanning is performed and theoretical information is included. In the second part, the purpose of the study, the problem status, the importance of the study, limitations, assumptions, problem question, research method, research universe and sample are specified and informed. In the third section, the data obtained using appropriate statistical methods are analyzed. In the last section, some important suggestions and comments are made in the light of the data obtained. 展开更多
关键词 Psycho-Social Effect of Facebook Facebook and Personal harms Habitual Activity of Using Facebook Nickname Usage and Social Sharing Nets
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Combustion mechanism and control approaches of underground coal fires:a review 被引量:3
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作者 Yuntao Liang Yalan Yang +2 位作者 Sida Guo Fuchao Tian Shaofeng Wang 《International Journal of Coal Science & Technology》 EI CAS CSCD 2023年第2期58-82,共25页
With the large-scale mining of coal resources,the huge economic losses and environmental problems caused by underground coal fires have become increasingly prominent,and the research on the status quo and response str... With the large-scale mining of coal resources,the huge economic losses and environmental problems caused by underground coal fires have become increasingly prominent,and the research on the status quo and response strategies of underground coal fires is of great significance to accelerate the green prevention and control of coal fires,energy conservation and emission reduction.In this paper,we summarized and sorted out the research status of underground coal fires,focused on the theoretical and technical issues such as underground coal fire combustion mechanism,multiphysics coupling effect of coal fire combustion,fire prevention and extinguishing technology for underground coal fires,and beneficial utilization technology,and described the latest research progress of the prevention and control for underground coal fire hazards.Finally,the key research problems in the field of underground coal fire hazards prevention and control were proposed in the direction of the basic theory,technology research,comprehensive management and utilization,with a view to providing ideas and solutions for the management of underground coal fires. 展开更多
关键词 Underground coal fire Combustion mechanism Multiphysics coupling effect Disaster prevention and control Turning harm into benefit Response strategy
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Factors inducing morphological transition in harmful algal bloom-forming species Phaeocystis globosa with emphasis on predator chemical cue
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作者 Xiao YANG Pingping SHEN Ke LI 《Journal of Oceanology and Limnology》 SCIE CAS CSCD 2023年第4期1537-1546,共10页
The microalga Phaeocystis globosa is recognized as a harmful alga and also one of the few keystone phytoplankton genera that shape the structure and function of marine ecosystems.P.globosa possess a complex polymorphi... The microalga Phaeocystis globosa is recognized as a harmful alga and also one of the few keystone phytoplankton genera that shape the structure and function of marine ecosystems.P.globosa possess a complex polymorphic life cycle,exhibiting phase alternation between free-living cells of approximately 3-6μm in diameter and gelatinous colonies(palmelloid stage)reaching several millimeters.The knowledge on the factors that induced the morphological transition of P.globosa in the last two decades was reviewed.Emphasis is given to infochemicals,an additional biological factor induced by predator,with the attempt to reveal a relevant mechanism of induced morphological defense. 展开更多
关键词 Phaeocystis globosa POLYMORPHISMS harmful algal blooms defense strategies INFOCHEMICAL
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Comparison of short-term toxicity of 14 common phycotoxins(alone and in combination)to the survival of brine shrimp Artemia salina
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作者 Yuting Zhang Shanshan Song +7 位作者 Bin Zhang Yang Zhang Miao Tian Ziyi Wu Huorong Chen Guangmao Ding Renyan Liu Jingli Mu 《Acta Oceanologica Sinica》 SCIE CAS CSCD 2023年第2期134-141,共8页
Toxic harmful algal blooms(HABs)can cause deleterious effects in marine organisms,threatening the stability of marine ecosystems.It is well known that different strains,natural populations and growth conditions of the... Toxic harmful algal blooms(HABs)can cause deleterious effects in marine organisms,threatening the stability of marine ecosystems.It is well known that different strains,natural populations and growth conditions of the same toxic algal species may lead to different amount of phycotoxin production and the ensuing toxicity.To fully assess the ecological risk of toxic HABs,it is of great importance to investigate the toxic effects of phycotoxins in marine organisms.In this study,the short-term toxicity of 14 common phycotoxins(alone and in combination)in the marine zooplankton Artemia salina was investigated.The 48 h LC_(50)of the 14 phycotoxins varied from 0.0193µg/mL to 2.415µg/mL.The most potent phycotoxin was azaspiracids-3(AZA3;with a LC_(50)of 0.0193µg/mL),followed by azaspiracids-2(AZA2;0.0226µg/mL),pectenotoxin-2(PTX2;0.0460µg/mL)and dinophysistoxin-1(DTX1;0.0818µg/mL).For the binary exposure,okadaic acid(OA)induced potential additive effects with DTX1,probably due to their similar structure(polyether fatty acid)and mode of action(attacking the serine/threonine phosphoprotein phosphatases).On the other hand,OA showed potential antagonistic effects with PTX2,which might be accounted for by their activation on the detoxification activity of cytochrome P450 activity.In addition,DTX1 induced potential synergetic effects with saxitoxin(STX),yessotoxin(YTX)or PTX2,suggesting the hazard potency of the mixtures of DTX1 and other phycotoxins(like STX,YTX and PTX2)with regard to the ecological risk.These results provide valuable toxicological data for assessing the impact of phycotoxins on marine planktonic species and highlight the potential ecological risk of toxic HABs in marine ecosystems. 展开更多
关键词 LC_(50) harmful algal blooms binary exposure ecological risk
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Artisanal Mining and Soil Quality in the Sudano-Sahelian Climate: Case of the Artisanal Mining Site of Yimiougou in Burkina Faso, West Africa
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作者 Nicolas Kagambega Urbain Sam Mathias Ouedraogo 《Journal of Environmental Protection》 CAS 2023年第1期1-15,共15页
The majority of the population of Burkina Faso lives from agriculture and therefore depends on the land. The main objective of this study is to assess the quality of the soils in the area linked to artisanal mining ac... The majority of the population of Burkina Faso lives from agriculture and therefore depends on the land. The main objective of this study is to assess the quality of the soils in the area linked to artisanal mining activities. The methodology adopted consisted in sampling and characterizing the main types of soil. In order to assess the level of soil pollution by artisanal mining, parameters such as the geo-accumulation index (Igeo) and the contamination factor (CF) are calculated. A prediction of acid mine drainage (AMD) was also carried out on samples of mine tailings which are potential sources of pollution of these soils. The results obtained show that the soils in Yimiougou are of nil to low agronomic interest. The Igeo shows that for lead, copper, zinc and arsenic the levels found in the different morphological units are partly attributable to human action and specifically artisanal mining. The values of the contamination factor indicate contamination. Cobalt presents the lowest contamination. For cadmium, the different types of soil are moderately contaminated except for the FITLC type, which has a CF value of 0.50, therefore synonymous with low or absent contamination. The various morphological units studied are very heavily contaminated with zinc, copper, lead and arsenic. The pH and conductivity values indicate that the mine tailings samples are non-acidogenic, therefore not yet oxidized. As for the sulphide contents, they show that only samples S17, S22, S23 and S24 present values that are strictly above the threshold (0.3%) and therefore potentially acid-generating. The comparative study of the acid potential (AP) and the neutralization potential (NP) reveals that the neutralization potentials of the different samples are clearly higher than the acid potentials even for the samples which present a proven acidification potential (S17, S22, S23 and S24). These results show that the mine tailings have the natural capacity to neutralize any possible mine drainage, given the presence of acid-eating minerals such as the carbonates associated with the mineralization. 展开更多
关键词 Soil Artisanal Mining Environment Heavy Metals Potentially Harmful Elements Burkina Faso
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