Medical education is an important cornerstone for the development of healthcare,and medical humanities education,as an integral part of medical education,plays an irreplaceable role in cultivating people’s health gua...Medical education is an important cornerstone for the development of healthcare,and medical humanities education,as an integral part of medical education,plays an irreplaceable role in cultivating people’s health guardians with high medical ethics.We adopted the method of stratified random sampling to select 309 students and 107 faculty members from three independent medical colleges in Sichuan province as the research subjects and distributed questionnaire surveys investigating in three dimensions:overall cognition of medical humanities,evaluation of medical humanistic qualities,and the current situation of medical humanities education,supplemented by an in-depth literature review and interviews with subject matter experts.We found that“tech-centrism”still has a great influence,the self-evaluation of medical students’humanistic quality is generally not high,the educational concept of“emphasizing professional skills over morality”of faculty and staff is still quite prevalent,and there is still the“last mile”phenomenon in medical humanities education.In order to promote the integrated development of“new medicine”and“new liberal arts”and break the barriers of“tech-centrism”and“instrumental rationality,”it is necessary to change the educational concept and strengthen the education of all employees,break through the bottleneck of internships and strengthen the whole process of education,integrate educational resources and strengthen all-round education,improve the incentive mechanisms,strengthen the assessment methods,and provide Chinese wisdom and Chinese solutions for the development of medical humanities education.展开更多
The present paper takes the English translation of the introduction of Xianda College of Economics and Humanities,SISU as an example to explore the translation problems of proper nouns and differences in English and C...The present paper takes the English translation of the introduction of Xianda College of Economics and Humanities,SISU as an example to explore the translation problems of proper nouns and differences in English and Chinese language expressions in the construction of English introductions in Chinese institutions of higher education with the intention to propose corresponding solutions.It is hoped that this paper will provide some tips for the English translation of international publicity materials for other institutions of higher education.展开更多
Humanities and Social Sciences(HSS) are undergoing the transformation of spatialization and quantification. Geo-computation, with geoinformatics(including RS: Remote Sensing;GIS: Geographical Information System;GNSS: ...Humanities and Social Sciences(HSS) are undergoing the transformation of spatialization and quantification. Geo-computation, with geoinformatics(including RS: Remote Sensing;GIS: Geographical Information System;GNSS: Global Navigation Satellite System), provides effective computational and spatialization methods and tools for HSS. Spatial Humanities and Geo-computation for Social Sciences(SH&GSS) is a field coupling geo-computation, and geoinformatics, with HSS. This special issue accepted a set of contributions highlighting recent advances in methodologies and applications of SH&GSS, which are related to sentiment spatial analysis from social media data, emotional change spatial analysis from news data, spatial analysis of social media related to COVID-19, crime spatiotemporal analysis, “double evaluation” for Land Use/Land Cover(LUCC), Specially Protected Natural Areas(SPNA) analysis, editing behavior analysis of Volunteered Geographic Information(VGI), electricity consumption anomaly detection, First and Last Mile Problem(FLMP) of public transport, and spatial interaction network analysis for crude oil trade network. Based on these related researches, we aim to present an overview of SH&GSS, and propose some future research directions for SH&HSS.展开更多
At this point in time,the importance of medical humanities education has not been fully understood during the standardized training of residents in China.The study of medical humanities is an important facet of ophtha...At this point in time,the importance of medical humanities education has not been fully understood during the standardized training of residents in China.The study of medical humanities is an important facet of ophthalmology residency that needs to be strengthened.During the standardized training of ophthalmology residents,not only the medical sciences should be strengthened,but also the nature and practice of medical humanities knowledge should be enhanced in multiple aspects.Offering medically-relevant literature,history,philosophy and other courses,simulating real medical activities,being enthusiastic in popular medical science and increasing the contents of the examination in medical humanities would all be areas that would further advance the ophthalmology residency.Along with medical science education,residents will be led and trained on medical humanities as to build good medical humanistic spirit of patient care so that they may better serve patients.展开更多
The coronavirus disease 2019 pandemic represents an enduring transformation in health care and education with the advancement of smart universities,telehealth,adaptive research protocols,personalized medicine,and self...The coronavirus disease 2019 pandemic represents an enduring transformation in health care and education with the advancement of smart universities,telehealth,adaptive research protocols,personalized medicine,and self-controlled or artificial intelligence-controlled learning.These changes,of course,also cover mental health and long-term realignment of coronavirus disease 2019 survivors.Fatigue or anxiety,as the most prominent psychiatric“long coronavirus disease 2019”symptoms,need a theory-based and empirically-sound procedure that would help us grasp the complexity of the condition in research and treatment.Considering the systemic character of the condition,such strategies have to take the whole individual and their sociocultural context into consideration.Still,at the moment,attempts to build an integrative framework for providing meaning and understanding for the patients of how to cope with anxiety when they are confronted with empirically reduced parameters(e.g.,severe acute respiratory syndrome coronavirus type 2)or biomarkers(e.g.,the FK506 binding protein 5)are rare.In this context,multidisciplinary efforts are necessary.We therefore join in a plea for an establishment of‘translational medical humanities’that would allow a more straightforward intervention of humanities(e.g.,the importance of the therapist variable,continuity,the social environment,etc)into the disciplinary,medial,political,and popular cultural debates around health,health-care provision,research(e.g.,computer scientists for simulation studies),and wellbeing.展开更多
To improve high quality and/or retain achieved high quality of an academic program, time to time evaluation for quality of each covered course is often an integrated aspect considered in reputed institutions, however,...To improve high quality and/or retain achieved high quality of an academic program, time to time evaluation for quality of each covered course is often an integrated aspect considered in reputed institutions, however, there has been little effort regarding humanities courses. This research article deals with analysis of evaluation data collected regarding humanities course from a College of Commerce & Economics, Mumbai, Maharashtra, India, on Likert type items. Appropriateness of one parametric measure and three non-parametric measures are discussed and used in this regard which could provide useful clues for educational policy planners. Keeping in view of the analytical results using these four measures, regardless of the threshold regarding satisfaction among students, overall performance of almost every subject has been un-satisfactory. There is a need to make a focused approach to take every course at the level of high performance. The inconsistency noticed under every threshold further revealed that under such poorly performing subjects globally, one needs to analyze merely at the global level item. Once the global level analysis reveals high performance of a course, then only item specific analysis may need to be focused to find out the items requiring further improvements.展开更多
The move identification of the present study followed the four-move model of V.K.Bhatia who is the representative personage of ESP.It is composed of four moves(1993):Introducing purpose,Describing methodology,Summariz...The move identification of the present study followed the four-move model of V.K.Bhatia who is the representative personage of ESP.It is composed of four moves(1993):Introducing purpose,Describing methodology,Summarizing results and Presenting conclusions.According to the above theory,Principles of the scientific method of sampling suggested by Nwogu(1997:121)as to the selection of journal were adopted in the study—representativity,reputation,accessibility.The focus is the analysis of move structures of abstract sections of them and contrastive studies between Economics and Humanities&Social Sciences of Lanzhou Jiaotong University in different moves of abstract sections.We find there are some similarities and differences between them.In general,the abstracts of Humanities&Social Sciences are more standard than Economics,which suggested English abstract sections of some Economics bachelor’s degree thesis need to be improved.展开更多
This action research which situates itself in the context of Digital Humanities focuses on engaging students of Introductory Chinese course with an assignment to create podcasts in the form of an interview.Requiring s...This action research which situates itself in the context of Digital Humanities focuses on engaging students of Introductory Chinese course with an assignment to create podcasts in the form of an interview.Requiring students to integrate the aural,oral,and textural information via technology so as to carry a conversation with an interlocutor challenges them to convey their thoughts from the language they think in into meaningful ideas using the target language.In this way,students are“pushed”to convert their listening,speaking,and writing from being isolated components into a more dynamic and cohesive mode of communicating.As they explore expressing their ideas in the language they are learning,they develop the skills and sensibility needed to critically analyze their own work.Although limited in scale,the podcast format urges students to transform what they need to learn into a familiar product.展开更多
Among modern Chinese philosophers,Feng Youlan surpasses others in theoretical clarity,but he is also the most controversial. is paper tries to reveal the tension in Feng Youlan’s philosophizing through the lens of hi...Among modern Chinese philosophers,Feng Youlan surpasses others in theoretical clarity,but he is also the most controversial. is paper tries to reveal the tension in Feng Youlan’s philosophizing through the lens of his awkward position in the changing system of humanities education.It points out some misunderstandings in contemporary research on Feng’s philosophy and further discusses solutions to that problem.展开更多
Dickens, a great realist novelist in his time, captured the popularity as no other novelist had done. And Oliver Twist,one of his successful works, greatly displays his genius in the novel. Oliver is a perfect figure ...Dickens, a great realist novelist in his time, captured the popularity as no other novelist had done. And Oliver Twist,one of his successful works, greatly displays his genius in the novel. Oliver is a perfect figure created by Dickens. In this paper, we will discuss the humanities by analyzing Oliver's personality and thus build a better understanding of the novel and the great writer Dickens.展开更多
With the reform of China’s educational undertakings,in the daily teaching activities,various universities and colleges in China have gradually begun to attach importance to the cultivation of literature education and...With the reform of China’s educational undertakings,in the daily teaching activities,various universities and colleges in China have gradually begun to attach importance to the cultivation of literature education and the cultivation of university and college students’Humanities quality.As a kind of discipline integrating art and humanity,literature education plays an important role in the cultivation of university and college students’humanities quality.Based on this,this paper conducts a simple analysis of the role of literature education in the quality cultivation and university college students,the current situation of China’s literature education in universities and colleges and the cultivation of university and college students’humanities quality and related optimization measures.It is hoped that there will be inspiration and help for improving the humanities quality of university and college students in China and giving play to the role of literature education.展开更多
As the special activity to commemorate the 11^th UN Chinese Language Day,Beijing Language and Culture University hosted the International Humanities Forum of"Spreading of Sinology and Chinese Language during the ...As the special activity to commemorate the 11^th UN Chinese Language Day,Beijing Language and Culture University hosted the International Humanities Forum of"Spreading of Sinology and Chinese Language during the Epidemic"on April 19,2020.展开更多
With its rising number of publications and expanding international collaborations,China's humanities and social sciences(HSS)research is displaying its potential for global prominence.Researchers have been explori...With its rising number of publications and expanding international collaborations,China's humanities and social sciences(HSS)research is displaying its potential for global prominence.Researchers have been exploring the development of China's HSS from different perspectives.However,the examinations from the perspective of sentiment analysis are scanty.Our aim is then to examine the sentiment features in Chinese HSS academic writing,by analyzing a large-scale corpus with over 275 million characters and with a time span from 2000 to 2020.Considering that most studies only focused on abstracts,we examined both the abstracts and the full texts,as well as a direct comparison between them.We found that Chinese HSS academic writing has evolved to be more positively biased in the past two decades,showing an upward trend in the use of positive words and a slight downward trend in the use of negative words.However,the upward trend of positive words in the full texts is not that clear,resembling a fluctuating pattern.Regarding the comparison,the abstracts are more likely to use positive words while the full texts tend to use more negative words.These phenomena can be explained with the social cognitive theory,in that they may be shaped by a joint force of the nature of human beings,the nature of language,the particular socio-cultural background in China and the features of the academic genre.展开更多
The spatial information of literature refers to the representation of physical or conscious space in literary works,including position,shape,structure,features,and relationships.The spatial information organization an...The spatial information of literature refers to the representation of physical or conscious space in literary works,including position,shape,structure,features,and relationships.The spatial information organization and its method are essential to the whole process of literature production,circulation,acceptance,and reproduction,which is conducive to a deeper exploration of the aesthetic essence of literature in the information era.Taking the organization of spatial information in science fiction as an example,this paper investigates the way of interaction between informatics and literature,explores the function of spatial information in the narrative of science fiction,and discovers digital humanistic laws of literary information organization.This study finds that the spatial information of early science fiction is organized in horizontal,vertical,axial,and causal modes;in the era of digital humanities,influenced by information technology such as the internet,virtual reality,and artificial intelligence,literary space has experienced revolutions characteristic of time-space integration,boundary dissolution,dimensional change,and virtualization;the spatial information organization of contemporary science fiction adopts nested,reticulated,parallel,interactive,and reverse patterns;on the whole,it is featured with fluidity,chaos,correlation,and mutation,creating a unique digital humanistic spectacle.展开更多
Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not...Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not well understood.Type-ⅡBMP receptor(BMPRⅡ),the cognate receptor,is expressed by neural precursor cells during embryogenesis;however,an in vitro method of enriching BMPRⅡ^(+)human neural precursor cells(hNPCs)from the fetal spinal cord is absent.Immunofluorescence was undertaken on intact second-trimester human fetal spinal cord using antibodies to BMPRⅡand leukemia inhibitory factor(LIF).Regions of highest BMPRⅡ^(+)immunofluorescence localized to sensory columns.Parenchymal and meningeal-associated BMPRⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage markers,CD34/CD39.LIF immunostaining identified a population of somas concentrated in dorsal and ventral horn interneurons,mirroring the expression of LIF receptor/CD118.A combination of LIF supplementation and high-density culture maintained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,cytoarchitecture.These neurospheres were characterized by BMPRⅡ^(+)/MAP2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vimentin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vimentin^(+)/GFAP^(+)/MAP2ab^(–)/NeuN^(–)multipotent precursors.Dissociated cultures from tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage cells.Fluorescence-activated cell sorting-sorted BMPRⅡ^(+)hNPCs were MAP2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in culture.This is the first isolation of BMPRⅡ^(+)hNPCs identified and characterized in human fetal spinal cords.Our data show that LIF combines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterized by surface BMPRⅡ^(+)hNPCs.Our study has provided a new methodology for an in vitro model capable of amplifying human fetal spinal cord cell numbers for>10 passages.Investigations of the role BMPRⅡplays in spinal cord development have primarily relied upon mouse and rat models,with interpolations to human development being derived through inference.Because of significant species differences between murine biology and human,including anatomical dissimilarities in central nervous system(CNS)structure,the findings made in murine models cannot be presumed to apply to human spinal cord development.For these reasons,our human in vitro model offers a novel tool to better understand neurodevelopmental pathways,including BMP signaling,as well as spinal cord injury research and testing drug therapies.展开更多
We present our approach for constructing a federated searching system for Japanese humanities digital libraries using automatic metadata mapping.We discuss some achievements in the ongoing research to construct a fede...We present our approach for constructing a federated searching system for Japanese humanities digital libraries using automatic metadata mapping.We discuss some achievements in the ongoing research to construct a federated searching system. The goals of this system are(1) to perform metadata mapping automatically for Japanese heterogeneous humanities digital libraries and(2) to let users access multiple humanities digital libraries by using only one query input.The proposed automatic metadata mapping method produced the average mapping precision of 94.9%.We also address the metadata-related challenges facing Japanese humanities databases.展开更多
Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECM) interactions leading to assembly of integrin a...Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECM) interactions leading to assembly of integrin adhesion complexes(IACs) that initiate many signaling functions both at the membrane and deeper within the cytoplasm to coordinate processes including cell adhesion, migration, proliferation, survival, differentiation, and metabolism. All metazoan organisms possess integrins, and it is generally agreed that integrins were associated with the evolution of multicellularity, being essential for the association of cells with their neighbors and surroundings, during embryonic development and many aspects of cellular and molecular biology. Integrins have important roles in many aspects of embryonic development, normal physiology, and disease processes with a multitude of functions discovered and elucidated for integrins that directly influence many areas of biology and medicine, including mammalian pregnancy, in particular implantation of the blastocyst to the uterine wall, subsequent placentation and conceptus(embryo/fetus and associated placental membranes) development. This review provides a succinct overview of integrin structure, ligand binding, and signaling followed with a concise overview of embryonic development, implantation, and early placentation in pigs, sheep, humans, and mice as an example for rodents. A brief timeline of the initial localization of integrin subunits to the uterine luminal epithelium(LE) and conceptus trophoblast is then presented, followed by sequential summaries of integrin expression and function during gestation in pigs, sheep, humans, and rodents. As appropriate for this journal, summaries of integrin expression and function during gestation in pigs and sheep are in depth, whereas summaries for humans and rodents are brief. Because similar models to those illustrated in Fig. 1, 2, 3, 4, 5 and 6 are present throughout the scientific literature, the illustrations in this manuscript are drafted as Viking imagery for entertainment purposes.展开更多
Objective:To determine the relationship between teratozoospermia and sperm DNA fragmentation(SDF)in the human ejaculate.Methods:This retrospective study included 100 normozoospermic men as a control cohort(abnormal fo...Objective:To determine the relationship between teratozoospermia and sperm DNA fragmentation(SDF)in the human ejaculate.Methods:This retrospective study included 100 normozoospermic men as a control cohort(abnormal forms>14%),210 patients with a high level of abnormal forms(≤4%)and 65 patients presenting with a moderate level of abnormal forms(>4%to≤14%)based on the World Health Organization definitions.Sperm morphology was assessed using bright field microscopy.Sperm DNA fragmentation was assessed using the sperm chromatin dispersion assay.Non-parametric analyses were conducted to examine the relationship between abnormal sperm morphology and sperm DNA fragmentation;receiver operating characteristic(ROC)analyses were conducted to assess sensitivity and specificity of this relationship.Results:A correlation analysis revealed that the higher the proportion of abnormal spermatozoa in the ejaculate,the higher the level of SDF(Spearman's Rho=-0.230;P<0.001).Significant differences in the proportion of SDF were found when all cohorts were compared(P<0.001);these significant differences were also retained when the different cohorts were compared pairwise.ROC analysis showed a moderate but significant predictive value for SDF to differentiate patients with different levels of teratozoospemia.Conclusions:Although analysis of a more continuous range of values for teratozoospermia would help further clarify any causal relationship with SDF,there is clearly a synergistic or coincident affiliation between these variables that needs to be acknowledged by the clinician when interpreting the spermiogram.展开更多
基金funded by the Ministry of Education Demonstration Excellent Teaching and Research Team Construction Project:Research on the Effectiveness Improvement of Ideological and Political Theory Courses in Medical Universities(19JDSZK008)the Education Work Committee of Sichuan Provincial Committee of the Communist Party of China“All-staff,Whole-process,and All-round Education”Comprehensive Reform Pilot Colleges(Majors)Project:“Research and Practice on the Collaborative Education Mechanism of the Integration of Medical Humanistic Spirit and Ideological and Political Courses.”。
文摘Medical education is an important cornerstone for the development of healthcare,and medical humanities education,as an integral part of medical education,plays an irreplaceable role in cultivating people’s health guardians with high medical ethics.We adopted the method of stratified random sampling to select 309 students and 107 faculty members from three independent medical colleges in Sichuan province as the research subjects and distributed questionnaire surveys investigating in three dimensions:overall cognition of medical humanities,evaluation of medical humanistic qualities,and the current situation of medical humanities education,supplemented by an in-depth literature review and interviews with subject matter experts.We found that“tech-centrism”still has a great influence,the self-evaluation of medical students’humanistic quality is generally not high,the educational concept of“emphasizing professional skills over morality”of faculty and staff is still quite prevalent,and there is still the“last mile”phenomenon in medical humanities education.In order to promote the integrated development of“new medicine”and“new liberal arts”and break the barriers of“tech-centrism”and“instrumental rationality,”it is necessary to change the educational concept and strengthen the education of all employees,break through the bottleneck of internships and strengthen the whole process of education,integrate educational resources and strengthen all-round education,improve the incentive mechanisms,strengthen the assessment methods,and provide Chinese wisdom and Chinese solutions for the development of medical humanities education.
文摘The present paper takes the English translation of the introduction of Xianda College of Economics and Humanities,SISU as an example to explore the translation problems of proper nouns and differences in English and Chinese language expressions in the construction of English introductions in Chinese institutions of higher education with the intention to propose corresponding solutions.It is hoped that this paper will provide some tips for the English translation of international publicity materials for other institutions of higher education.
基金National Natural Science Foundation of China(No.42171448)。
文摘Humanities and Social Sciences(HSS) are undergoing the transformation of spatialization and quantification. Geo-computation, with geoinformatics(including RS: Remote Sensing;GIS: Geographical Information System;GNSS: Global Navigation Satellite System), provides effective computational and spatialization methods and tools for HSS. Spatial Humanities and Geo-computation for Social Sciences(SH&GSS) is a field coupling geo-computation, and geoinformatics, with HSS. This special issue accepted a set of contributions highlighting recent advances in methodologies and applications of SH&GSS, which are related to sentiment spatial analysis from social media data, emotional change spatial analysis from news data, spatial analysis of social media related to COVID-19, crime spatiotemporal analysis, “double evaluation” for Land Use/Land Cover(LUCC), Specially Protected Natural Areas(SPNA) analysis, editing behavior analysis of Volunteered Geographic Information(VGI), electricity consumption anomaly detection, First and Last Mile Problem(FLMP) of public transport, and spatial interaction network analysis for crude oil trade network. Based on these related researches, we aim to present an overview of SH&GSS, and propose some future research directions for SH&HSS.
文摘At this point in time,the importance of medical humanities education has not been fully understood during the standardized training of residents in China.The study of medical humanities is an important facet of ophthalmology residency that needs to be strengthened.During the standardized training of ophthalmology residents,not only the medical sciences should be strengthened,but also the nature and practice of medical humanities knowledge should be enhanced in multiple aspects.Offering medically-relevant literature,history,philosophy and other courses,simulating real medical activities,being enthusiastic in popular medical science and increasing the contents of the examination in medical humanities would all be areas that would further advance the ophthalmology residency.Along with medical science education,residents will be led and trained on medical humanities as to build good medical humanistic spirit of patient care so that they may better serve patients.
文摘The coronavirus disease 2019 pandemic represents an enduring transformation in health care and education with the advancement of smart universities,telehealth,adaptive research protocols,personalized medicine,and self-controlled or artificial intelligence-controlled learning.These changes,of course,also cover mental health and long-term realignment of coronavirus disease 2019 survivors.Fatigue or anxiety,as the most prominent psychiatric“long coronavirus disease 2019”symptoms,need a theory-based and empirically-sound procedure that would help us grasp the complexity of the condition in research and treatment.Considering the systemic character of the condition,such strategies have to take the whole individual and their sociocultural context into consideration.Still,at the moment,attempts to build an integrative framework for providing meaning and understanding for the patients of how to cope with anxiety when they are confronted with empirically reduced parameters(e.g.,severe acute respiratory syndrome coronavirus type 2)or biomarkers(e.g.,the FK506 binding protein 5)are rare.In this context,multidisciplinary efforts are necessary.We therefore join in a plea for an establishment of‘translational medical humanities’that would allow a more straightforward intervention of humanities(e.g.,the importance of the therapist variable,continuity,the social environment,etc)into the disciplinary,medial,political,and popular cultural debates around health,health-care provision,research(e.g.,computer scientists for simulation studies),and wellbeing.
文摘To improve high quality and/or retain achieved high quality of an academic program, time to time evaluation for quality of each covered course is often an integrated aspect considered in reputed institutions, however, there has been little effort regarding humanities courses. This research article deals with analysis of evaluation data collected regarding humanities course from a College of Commerce & Economics, Mumbai, Maharashtra, India, on Likert type items. Appropriateness of one parametric measure and three non-parametric measures are discussed and used in this regard which could provide useful clues for educational policy planners. Keeping in view of the analytical results using these four measures, regardless of the threshold regarding satisfaction among students, overall performance of almost every subject has been un-satisfactory. There is a need to make a focused approach to take every course at the level of high performance. The inconsistency noticed under every threshold further revealed that under such poorly performing subjects globally, one needs to analyze merely at the global level item. Once the global level analysis reveals high performance of a course, then only item specific analysis may need to be focused to find out the items requiring further improvements.
文摘The move identification of the present study followed the four-move model of V.K.Bhatia who is the representative personage of ESP.It is composed of four moves(1993):Introducing purpose,Describing methodology,Summarizing results and Presenting conclusions.According to the above theory,Principles of the scientific method of sampling suggested by Nwogu(1997:121)as to the selection of journal were adopted in the study—representativity,reputation,accessibility.The focus is the analysis of move structures of abstract sections of them and contrastive studies between Economics and Humanities&Social Sciences of Lanzhou Jiaotong University in different moves of abstract sections.We find there are some similarities and differences between them.In general,the abstracts of Humanities&Social Sciences are more standard than Economics,which suggested English abstract sections of some Economics bachelor’s degree thesis need to be improved.
文摘This action research which situates itself in the context of Digital Humanities focuses on engaging students of Introductory Chinese course with an assignment to create podcasts in the form of an interview.Requiring students to integrate the aural,oral,and textural information via technology so as to carry a conversation with an interlocutor challenges them to convey their thoughts from the language they think in into meaningful ideas using the target language.In this way,students are“pushed”to convert their listening,speaking,and writing from being isolated components into a more dynamic and cohesive mode of communicating.As they explore expressing their ideas in the language they are learning,they develop the skills and sensibility needed to critically analyze their own work.Although limited in scale,the podcast format urges students to transform what they need to learn into a familiar product.
基金This paper is a preliminary result of Studies on the Creative Transformation and Innovative Development of Traditional Chinese Culture[中华优秀传统文化的创造性转化与创新性发展研究]supported by a major project of the National Social Science Fund of China(Project No.2015MZD014)of Studies on Modernity and Contemporary Chinese Philosophy[现代性与中国当代哲学研究]supported by a key program of the National Social Sciences Fund of China(Project No.13AZX012).
文摘Among modern Chinese philosophers,Feng Youlan surpasses others in theoretical clarity,but he is also the most controversial. is paper tries to reveal the tension in Feng Youlan’s philosophizing through the lens of his awkward position in the changing system of humanities education.It points out some misunderstandings in contemporary research on Feng’s philosophy and further discusses solutions to that problem.
文摘Dickens, a great realist novelist in his time, captured the popularity as no other novelist had done. And Oliver Twist,one of his successful works, greatly displays his genius in the novel. Oliver is a perfect figure created by Dickens. In this paper, we will discuss the humanities by analyzing Oliver's personality and thus build a better understanding of the novel and the great writer Dickens.
文摘With the reform of China’s educational undertakings,in the daily teaching activities,various universities and colleges in China have gradually begun to attach importance to the cultivation of literature education and the cultivation of university and college students’Humanities quality.As a kind of discipline integrating art and humanity,literature education plays an important role in the cultivation of university and college students’humanities quality.Based on this,this paper conducts a simple analysis of the role of literature education in the quality cultivation and university college students,the current situation of China’s literature education in universities and colleges and the cultivation of university and college students’humanities quality and related optimization measures.It is hoped that there will be inspiration and help for improving the humanities quality of university and college students in China and giving play to the role of literature education.
文摘As the special activity to commemorate the 11^th UN Chinese Language Day,Beijing Language and Culture University hosted the International Humanities Forum of"Spreading of Sinology and Chinese Language during the Epidemic"on April 19,2020.
基金supported by the Social Science Foundation of Chongqing[Grant Number 2019QNYY51]the Science Foundation of Chongqing[Grant Number cstc2020jcyj-msxmX0554]+2 种基金the Fund of the Interdisciplinary Supervisor Team for Graduates Programs of Chongqing Municipal Education Commission[Grant Number YDSTD1923]the Fundamental Research Funds for the Central Universities[Grant Number 2021CDJSKZX07]the Graduate Research Innovation Program of Chongqing[Grant Number CYS22081].
文摘With its rising number of publications and expanding international collaborations,China's humanities and social sciences(HSS)research is displaying its potential for global prominence.Researchers have been exploring the development of China's HSS from different perspectives.However,the examinations from the perspective of sentiment analysis are scanty.Our aim is then to examine the sentiment features in Chinese HSS academic writing,by analyzing a large-scale corpus with over 275 million characters and with a time span from 2000 to 2020.Considering that most studies only focused on abstracts,we examined both the abstracts and the full texts,as well as a direct comparison between them.We found that Chinese HSS academic writing has evolved to be more positively biased in the past two decades,showing an upward trend in the use of positive words and a slight downward trend in the use of negative words.However,the upward trend of positive words in the full texts is not that clear,resembling a fluctuating pattern.Regarding the comparison,the abstracts are more likely to use positive words while the full texts tend to use more negative words.These phenomena can be explained with the social cognitive theory,in that they may be shaped by a joint force of the nature of human beings,the nature of language,the particular socio-cultural background in China and the features of the academic genre.
文摘The spatial information of literature refers to the representation of physical or conscious space in literary works,including position,shape,structure,features,and relationships.The spatial information organization and its method are essential to the whole process of literature production,circulation,acceptance,and reproduction,which is conducive to a deeper exploration of the aesthetic essence of literature in the information era.Taking the organization of spatial information in science fiction as an example,this paper investigates the way of interaction between informatics and literature,explores the function of spatial information in the narrative of science fiction,and discovers digital humanistic laws of literary information organization.This study finds that the spatial information of early science fiction is organized in horizontal,vertical,axial,and causal modes;in the era of digital humanities,influenced by information technology such as the internet,virtual reality,and artificial intelligence,literary space has experienced revolutions characteristic of time-space integration,boundary dissolution,dimensional change,and virtualization;the spatial information organization of contemporary science fiction adopts nested,reticulated,parallel,interactive,and reverse patterns;on the whole,it is featured with fluidity,chaos,correlation,and mutation,creating a unique digital humanistic spectacle.
基金supported by grants from the National Health and Medical Research Council(NHMRC)of Australia(Nos.571100 and 1048082)the Baxter Charitable Foundation(to TCL)+1 种基金Medical Research grants from the Rebecca L.Cooper Medical Research Foundation(to MWW,TCL,and MDL)supported by a Charles D.Kelman,M.D.Postdoctoral Award(2010)from the International Retinal Research Foundation(USA)。
文摘Roof plate secretion of bone morphogenetic proteins(BMPs)directs the cellular fate of sensory neurons during spinal cord development,including the formation of the ascending sensory columns,though their biology is not well understood.Type-ⅡBMP receptor(BMPRⅡ),the cognate receptor,is expressed by neural precursor cells during embryogenesis;however,an in vitro method of enriching BMPRⅡ^(+)human neural precursor cells(hNPCs)from the fetal spinal cord is absent.Immunofluorescence was undertaken on intact second-trimester human fetal spinal cord using antibodies to BMPRⅡand leukemia inhibitory factor(LIF).Regions of highest BMPRⅡ^(+)immunofluorescence localized to sensory columns.Parenchymal and meningeal-associated BMPRⅡ^(+)vascular cells were identified in both intact fetal spinal cord and cortex by co-positivity with vascular lineage markers,CD34/CD39.LIF immunostaining identified a population of somas concentrated in dorsal and ventral horn interneurons,mirroring the expression of LIF receptor/CD118.A combination of LIF supplementation and high-density culture maintained culture growth beyond 10 passages,while synergistically increasing the proportion of neurospheres with a stratified,cytoarchitecture.These neurospheres were characterized by BMPRⅡ^(+)/MAP2ab^(+/–)/βⅢ-tubulin^(+)/nestin^(–)/vimentin^(–)/GFAP^(–)/NeuN^(–)surface hNPCs surrounding a heterogeneous core ofβⅢ-tubulin^(+)/nestin^(+)/vimentin^(+)/GFAP^(+)/MAP2ab^(–)/NeuN^(–)multipotent precursors.Dissociated cultures from tripotential neurospheres contained neuronal(βⅢ-tubulin^(+)),astrocytic(GFAP+),and oligodendrocytic(O4+)lineage cells.Fluorescence-activated cell sorting-sorted BMPRⅡ^(+)hNPCs were MAP2ab^(+/–)/βⅢ-tubulin^(+)/GFAP^(–)/O4^(–)in culture.This is the first isolation of BMPRⅡ^(+)hNPCs identified and characterized in human fetal spinal cords.Our data show that LIF combines synergistically with high-density reaggregate cultures to support the organotypic reorganization of neurospheres,characterized by surface BMPRⅡ^(+)hNPCs.Our study has provided a new methodology for an in vitro model capable of amplifying human fetal spinal cord cell numbers for>10 passages.Investigations of the role BMPRⅡplays in spinal cord development have primarily relied upon mouse and rat models,with interpolations to human development being derived through inference.Because of significant species differences between murine biology and human,including anatomical dissimilarities in central nervous system(CNS)structure,the findings made in murine models cannot be presumed to apply to human spinal cord development.For these reasons,our human in vitro model offers a novel tool to better understand neurodevelopmental pathways,including BMP signaling,as well as spinal cord injury research and testing drug therapies.
基金Project supported by the Grant-in-Aid for the Global COE Program from the Ministry of Education,Culture,Sports,Science and Technology (MEXT) of Japan,and MEXT Grant-in-Aid for Strategic Formation of Research Infrastructure for Private University,Japan
文摘We present our approach for constructing a federated searching system for Japanese humanities digital libraries using automatic metadata mapping.We discuss some achievements in the ongoing research to construct a federated searching system. The goals of this system are(1) to perform metadata mapping automatically for Japanese heterogeneous humanities digital libraries and(2) to let users access multiple humanities digital libraries by using only one query input.The proposed automatic metadata mapping method produced the average mapping precision of 94.9%.We also address the metadata-related challenges facing Japanese humanities databases.
基金supported by USDA-NRICGP 98-35203-6337 to FWB.and RCB,NRSA DHHS/NIH 1-F32-HDO 8501 O1A1 to GAJ,USDA-NRI 2006-35203-17199 to GAJ and Kayla J.BaylessUSDA National Institute of Food and Agriculture Research Initiative Competitive Fellowship Grant no.2012-67011-19892 to James W.Frank and GAJ+1 种基金Agriculture and Food Research Initiative Competitive Grant no.2016-67015-24955 from the USDA National Institute of Food and Agriculture to GAJ and FWBNational Institutes of Health Grant 1R21HD071468-01 to GAJ and KJB。
文摘Integrins are a highly complex family of receptors that, when expressed on the surface of cells, can mediate reciprocal cell-to-cell and cell-to-extracellular matrix(ECM) interactions leading to assembly of integrin adhesion complexes(IACs) that initiate many signaling functions both at the membrane and deeper within the cytoplasm to coordinate processes including cell adhesion, migration, proliferation, survival, differentiation, and metabolism. All metazoan organisms possess integrins, and it is generally agreed that integrins were associated with the evolution of multicellularity, being essential for the association of cells with their neighbors and surroundings, during embryonic development and many aspects of cellular and molecular biology. Integrins have important roles in many aspects of embryonic development, normal physiology, and disease processes with a multitude of functions discovered and elucidated for integrins that directly influence many areas of biology and medicine, including mammalian pregnancy, in particular implantation of the blastocyst to the uterine wall, subsequent placentation and conceptus(embryo/fetus and associated placental membranes) development. This review provides a succinct overview of integrin structure, ligand binding, and signaling followed with a concise overview of embryonic development, implantation, and early placentation in pigs, sheep, humans, and mice as an example for rodents. A brief timeline of the initial localization of integrin subunits to the uterine luminal epithelium(LE) and conceptus trophoblast is then presented, followed by sequential summaries of integrin expression and function during gestation in pigs, sheep, humans, and rodents. As appropriate for this journal, summaries of integrin expression and function during gestation in pigs and sheep are in depth, whereas summaries for humans and rodents are brief. Because similar models to those illustrated in Fig. 1, 2, 3, 4, 5 and 6 are present throughout the scientific literature, the illustrations in this manuscript are drafted as Viking imagery for entertainment purposes.
文摘Objective:To determine the relationship between teratozoospermia and sperm DNA fragmentation(SDF)in the human ejaculate.Methods:This retrospective study included 100 normozoospermic men as a control cohort(abnormal forms>14%),210 patients with a high level of abnormal forms(≤4%)and 65 patients presenting with a moderate level of abnormal forms(>4%to≤14%)based on the World Health Organization definitions.Sperm morphology was assessed using bright field microscopy.Sperm DNA fragmentation was assessed using the sperm chromatin dispersion assay.Non-parametric analyses were conducted to examine the relationship between abnormal sperm morphology and sperm DNA fragmentation;receiver operating characteristic(ROC)analyses were conducted to assess sensitivity and specificity of this relationship.Results:A correlation analysis revealed that the higher the proportion of abnormal spermatozoa in the ejaculate,the higher the level of SDF(Spearman's Rho=-0.230;P<0.001).Significant differences in the proportion of SDF were found when all cohorts were compared(P<0.001);these significant differences were also retained when the different cohorts were compared pairwise.ROC analysis showed a moderate but significant predictive value for SDF to differentiate patients with different levels of teratozoospemia.Conclusions:Although analysis of a more continuous range of values for teratozoospermia would help further clarify any causal relationship with SDF,there is clearly a synergistic or coincident affiliation between these variables that needs to be acknowledged by the clinician when interpreting the spermiogram.
